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Jornais Acesso aberto

Jeremy Rundall, Alex Finer, Leslie Field, D McLaughlin, Brian Walkden, Jon Swain, Harold Hobson, Rob Hughes, Michael Manning, Edmund Crispin, Peter Marson, John Lambert, David Wilson, Stanley Devon, Peter Harland, Paul Jennings, Kenneth Pearson, Harold Frayman, John Howkins, James Poole, Gliff Temple, James Joint, Philip Oakes, Terry O'neill, Henry Brandon, John Russell, Richard Milner, Deryk Brown, J H Patterson, (Mrs) Christine Clark, Derek Jewell, Phnom Penh, Patrick Campbell, Peter Watson, W. R. Fogg Chairman, Norman Harris, James Gleeson, David Blundy, John R. Harris, Paul Eddy, Peter Ackroyd, David Rubinstein, Peter Kellner, Robin Marlar, Hugh Somerville, Cyril Connolly, Malcolm Crawford Economics Editor, Roger Eglin, Franklyn Wood, Jose da Fonseca, Marjorie Wallace, Maxwell Boyd, Tony Geraghty, John Fryer Labour Correspondent, Nicholas Carroll, Stanely Devon, John Hopkins, Keith Richardson Industrial Editor, Celia Haddon, Denis Herbstein, Robert Lacey, Peter Wilsher, Malcolm Winton, J K Liddle, John Raymond, (Mrs) Elaine Lever, David May, Desmond Shawe-Taylor, Pamela MacGregor-Morris, (Mrs) E. Eagles, Alan Brien, Gwen Nuttall, Michael Bateman, John Bell, Patrick Rowley, Dilys Powell, Russell Miller, Brough Scott, Tony Rocca, Oliver Gillie, Mike Bartholomew, Hugo Young, Don Anthony, Jack Ashley, Dudley Doust, Joseph Curtin, Ian Jack, Graham Searjeant Financial Editor, Stephen Fay, James Margach Political Correspondent, Antonia Fisher, Christopher Reed, Derek Humphry, Brian Glanville, Malcolm Muggeridge, Keith Richardson, Pamela Ure, Graham Searjeant, Anthony Holden, Peter Dunn, Dr. B. D. Gomperts, Maureen Walker, J Kenneth Jones, P W Fawcett, C. H. O'd. Alexander, Maurice Wiggin, Jacquetta Hawkes, Tim Rice, Allan Hall, Christopher Matthew, Philip Jacobson, John Hallows, Roland Adburgham, (Mrs) Jane Howell, Tom Shaw, Boris Schapiro, Nicholas Tomalin,

... The Horse of Mustapha Pasha, by Antoine-Jean Gros, France, 1806. Musee des ... May 3rd, 1808, by Francisco-Jose Goya y Lucientes, Spain, 1814. The Prado, ...

1973 - Gale Group | Sunday Times HA GDA

Artigo Acesso aberto Revisado por pares

E. Márquez Contreras, Vicente Gil-Guillén, J.J. Casado Martínez, Nieves Martel Claros, Mariano de la Figuera von Wichmann, J.L. Martín de Pablos, Francisco Atienza Martín, Teresa Gros García, Jacinto Espinosa García,

Analizar el incumplimiento farmacológico de la hipertensión arterial (HTA) en España, a partir de una revisión de estudios publicados entre 1984 y 2005. Revisión sistemática. Se realizó una búsqueda mediante internet (Medline e índice español de tesis doctorales), búsqueda manual de diferentes revistas españolas y referencias bibliográficas de artículos detectados sobre cumplimiento y contacto personalizado de expertos. Los descriptores fueron: hypertension and patient compliance, or compliance, or ...

Tópico(s): Cardiovascular Syncope and Autonomic Disorders

2006 - Elsevier BV | Atención Primaria

Jornais Acesso aberto

Anthony Harris, Jon Ashworth, David Adams, Freud, Gillian Bowditch Scotland Correspondent, Andrew Pierce, Simon Barnes, Jill Sherman Political Correspondent, Martin Fletcher and Ian Brodie, Alexandra Frean, Media Correspondent, Ronald Faux, Patricia Grayburn Arts Administator, Edward Kelleit-Bowman, Ross Tieman, Industrial Correspondent, Philip Howard, Michael Binyon, Jeremy Kingston, Malcolm Weller (Chairman), Richard Eaton, Simon Wilde, Colin Narbrough, Geoff Brown, Gerald Davies, Philip Bassett Industrial Editor, Joe Joseph, Bernard Levin, Jeremy Laurance, Health Services Correspondent, Ruth Gledhill, Religion Correspondent, Tom Shearer, John O'leary Education Editor, Kris Anderson, Peter Ball, Alan Johnson General Secretary, Raymond Keene Chess Correspondent, Peter Mandelson, Matthew May, Libby Purves, Alan Hamilton, Michael Clark, Philip Robinson, John Young, Christopher Apps, Charles Bremner, Jon Ashowth, Edward Gorman, John Hennessy, Robert Weale, Patricia Tehan, Banking Correspondent, Susan Gilchrist, Wolfgang M?nchau, Ian D. Lang, Malcolm Taylor, Jack Harris, Christopher Edgcombe, George Brock, Sydney Friskin, John Hopkins, Lin Jenkins, David Toop, Peter B. Baker, J. B. Kerr, Tim Jones, Transport Correspondent, Marcus Binney, Raymond Keene, Peter Davalle, Emma Wilkins, Lawrence Freedman, Dominic Haslam, Rodney Masters, Oliver Holt, Alex Hammond-Chambers, Barry Pickthall, Sir Alan Peacock, Solomon Malcolm, Roger Boyes, Nigel Hawkes, Science Editor, Robert Ballantyne, Ron Gribble, Kevin Eason and Vaughan Freeman, Kate Alderson, Julian Muscat, Adam Fresco, Richard Duce, Tim Judah, Balkans Correspondent, and our Foreign Staff, John Goodbody, Giles Whittell, G. S. Brazier, Edward Leigh, Caitlin Moran, Alan Lee, Walter Gammie, Philip Webster and Jill Sherman, Ben MacIntyre, Ian Brodie, Alan Lee Cricket Correspondent, Richard Beeston, Philip Pangalos, Stephen Pettitt, Lord Nelson, Doris Hollander Secretary, Michael Horsnell, Nicholas George, Tom Rhodes, Marianne Curphey, David Powell, Chris Moore, Patricia Tehan Banking Correspondent, Valerie Grove, Michael Henderson, Alan Jackson, Robert Ballantyne and Jon Ashworth, David Hands, Rugby Correspondent, Alan Gibson Deputy Director, Christopher Irvine, Sarah Bagnall Insurance Correspondent, Nick Nuttall and Michael Hornsby,

... ratings system to protect children, says Matthew May Gros International Limited Higginson & Partners International Federation of Air ... fab stirs again in the heart of San Francisco Seven Days What's out & about Council cannot ...

1994 - Gale Group | TDA

Artigo

A. M. Porto, Francisco E. Baralle, Eduardo G. Gros,

The biosynthesis of bufadienolides in Bufo paracnemis toads has been studied in different seasons of the year using [2-14C]mevalonic acid, [20-14C]pregnenolone, and [20-14C]cholesterol as precursors. The results showed that the doubly unsaturated δ-lactone ring of the bufadieno-lides is directly derived from the cholesterol side chain without the compound's prior conversion into pregnenolone. The probable sequence in which the different bufadienolides are formed is discussed.

Tópico(s): Steroid Chemistry and Biochemistry

1972 - Pergamon Press | Journal of Steroid Biochemistry

Jornais Acesso aberto

C. P. Bacon, G. S. Harwood, Dr. J. S. Murphy, Ed. Gros, Dr. O. W. Green,

... Sciatica, Dr. C. Morrosa, 1045 Mission St., San Francisco, Cal., Says, Famale Neurotics—Their Treatment, Suprarenal Extract ...

1901 - Gale Group | NCCO-STM 1of2

Artigo Acesso aberto Revisado por pares

Terje Sundstrøm, Lars Prestegarden, Francisco Azuaje, Synnøve Nymark Aasen, Gro Vatne Røsland, Jobin K. Varughese, Marzieh Bahador, Simon Bernatz, Yannick Braun, Patrick N. Harter, Kai Ove Skaftnesmo, Elizabeth S. Ingham, Lisa M. Mahakian, Sarah Tam, Clifford G. Tepper, Kjell Petersen, Katherine W. Ferrara, Karl Johan Tronstad, Morten Lund‐Johansen, Rudi Beschorner, Rolf Bjerkvig, Frits Thorsen,

Melanoma patients carry a high risk of developing brain metastases, and improvements in survival are still measured in weeks or months. Durable disease control within the brain is impeded by poor drug penetration across the blood-brain barrier, as well as intrinsic and acquired drug resistance. Augmented mitochondrial respiration is a key resistance mechanism in BRAF-mutant melanomas but, as we show in this study, this dependence on mitochondrial respiration may also be exploited therapeutically. ...

Tópico(s): Computational Drug Discovery Methods

2019 - Springer Science+Business Media | Acta Neuropathologica Communications

Artigo Acesso aberto Revisado por pares

Sara Pistone, Francisco M. Goycoolea, Alix Young, Gro Smistad, Marianne Hiorth,

The efficacy of treatments for oral ailments is often challenged by a low residence time of the conventional pharmaceutical formulations in the oral cavity. The residence time in the oral cavity could be improved by using bioadhesive formulations, such as preparations based on polysaccharides. This study describes the formulation and the evaluation of polysaccharide-based nanosystems as drug delivery systems addressed to the oral cavity. Nanoparticles based on chitosan, alginate or pectin were prepared ...

Tópico(s): Hydrogels: synthesis, properties, applications

2016 - Elsevier BV | European Journal of Pharmaceutical Sciences

Artigo Acesso aberto Revisado por pares

Krishna M. Talasila, Gro Vatne Røsland, Hanne R. Hagland, Eskil Eskilsson, Irene H. Flønes, Sabrina Fritah, Francisco Azuaje, Nadia A. Atai, Patrick N. Harter, Michel Mittelbronn, Michael Asger Andersen, Justin V. Joseph, Jubayer A. Hossain, Laurent Vallar, Cornelis J.F. Van Noorden, Simone P. Niclou, Frits Thorsen, Karl Johan Tronstad, Charalampos Tzoulis, Rolf Bjerkvig, Hrvoje Miletić,

Invasion and angiogenesis are major hallmarks of glioblastoma (GBM) growth. While invasive tumor cells grow adjacent to blood vessels in normal brain tissue, tumor cells within neovascularized regions exhibit hypoxic stress and promote angiogenesis. The distinct microenvironments likely differentially affect metabolic processes within the tumor cells.In the present study, we analyzed gene expression and metabolic changes in a human GBM xenograft model that displayed invasive and angiogenic phenotypes. ...

Tópico(s): Mitochondrial Function and Pathology

2016 - Oxford University Press | Neuro-Oncology

Artigo Acesso aberto Revisado por pares

C. Pérez-Rico, E. García-Romo, Juan Gros-Otero, Isabel Roldán‐Díaz, Juan Arévalo‐Serrano, Francisco Germaín, Román Blanco,

Purpose To evaluate visual function and its relationship to structure in adult amblyopic subjects. Methods This observational, cross-sectional study included 24 adult amblyopes and 19 healthy subjects. The amblyopes were separated into three groups: anisometropic amblyopes (n = 15), strabismic amblyopes (n = 5), and strabismic amblyopes with anisometropia (n = 4). The relationships of the multifocal visual evoked potential (VEP) results with the clinical findings and psychophysical (Humphrey visual field) ...

Tópico(s): Ophthalmology and Visual Impairment Studies

2014 - Lippincott Williams & Wilkins | Optometry and Vision Science

Artigo Acesso aberto Revisado por pares

D. Z. Wen, Aaron Rowland, Rik Derynck,

... Article1 June 1989free access Expression and secretion of gro/MGSA by stimulated human endothelial cells. D. Z. Wen D. Z. Wen Department of Developmental Biology, Genentech, Inc., South San Francisco, CA 94080. Search for more papers by this ...

Tópico(s): S100 Proteins and Annexins

1989 - Springer Nature | The EMBO Journal

Artigo Revisado por pares

Stéphane Brézillon, Jean‐Marie Zahm, Denis Pierrot, Dominique Gaillard, Jocelyne Hinnrasky, Hervé Millart, Jean‐Michel Klossek, Burkhard Tümmler, Édith Puchelle,

... rabbit anti-connexin 43 (dilution 1:50, Dr. Gros, University of Sciences of Luminy, Marseille, France), mouse anti-β1-integrin (dilution 1:20, Dr. Sheppard, Lung Biology Center, University of California, San Francisco, CA), rabbit anti-β-catenin (dilution 1:500, ...

Tópico(s): Neuroscience of respiration and sleep

1997 - Elsevier BV | Journal of Biological Chemistry

Artigo Acesso aberto Revisado por pares

Martha Enríquez Díaz, Jean‐Marie Volland, José Francisco Chávez Villegas, Dalila Aldana-Aranda, Olivier Gros,

The organogenesis, histogenesis and growth of larvae of the fighting conch Strombus pugilis (Linné, 1758) were studied over a period of 30 d after hatching in laboratory culture. Early development of S. pugilis was examined by light and scanning electron microscopy. Rearing was conducted at 27 ± 1 °C. Veligers were reared at 200 larvae l−1 in 4-l containers. Larvae were fed with the microalgae Isochrysis galbana and Nanochloropsis oculata at a concentration of 1,000 cell l−1. The protoconch at hatching ...

Tópico(s): Marine Biology and Ecology Research

2015 - Oxford University Press | Journal of Molluscan Studies

Artigo Revisado por pares

Francisco E. Baralle, Eduardo G. Gros,

Tópico(s): Plant biochemistry and biosynthesis

1969 - Elsevier BV | Phytochemistry

Editorial Revisado por pares

Pamela I. Erickson,

... abstract is available for this article. References Brundtland, Gro Harlem 2001 The Future of the World's Health. In Critical Issues in Global Health. C. Everett Koop, E. Pearson Clarence, and M. Roy Schwartz, eds. pp. 3– 11. San Francisco : Jossey-Bass. Hyder, Adnan Ali, and Richard H. ...

Tópico(s): Race, Genetics, and Society

2003 - Wiley | Medical Anthropology Quarterly

Artigo

David Wilsford,

... I Enrico Berlinger and Bettino Craxi Willy Brandt Gro Harlem Bruntland Santiago Carrillo Jacques Chirac AndRE Cools Alcide De Gaspari Charles de Gaulle Eaman de Valera Michel DebRE Joop den Uyl Willem Drees Ludwig Erhard Tage Erlander Thorbjorn Falldin Garret FitzGerald Harilaos Florakis Francisco Franco Hans-Dietrich Genscher Einar Gerhardsen Valery Giscard ...

Tópico(s): Eastern European Communism and Reforms

1995 - Association of College and Research Libraries | Choice Reviews Online

Artigo Acesso aberto Revisado por pares

Rosario Medina-Medina, E Iglesias-Flores, J M Benítez, Sandra Marín-Pedrosa, I Salgueiro, Gustavo Ferrín, Clara I. Linares, Sandra González‐Rubio, Pablo Jesús López‐Soto, Beatriz Gros, Cristina Villalba Moral, Francisco J. Álvarez, Manuel Rodríguez‐Perálvarez, E Chicano-Gálvez, Ignacio Ortea, Valle García-Sánchez, Patricia Aguilar‐Melero,

Therapy with anti-TNF has improved notably the management of Crohn's disease (CD).1 However, 25–40% of patients treated with these drugs lose response long-term.2 In addition, these treatments are expensive and not without risk of adverse events. Therefore, it is essential to identify reliable markers that will select those patients who can benefit of anti-TNF drugs, thus improving their efficacy and safety A consecutive cohort of CD patients, who were naïve to anti-TNF therapy, were enrolled and ...

Tópico(s): Chronic Lymphocytic Leukemia Research

2019 - Oxford University Press | Journal of Crohn s and Colitis

Artigo Acesso aberto

M. Alventosa-Zaidin, Guillem Pera, Carme Roca Saumell, N. Mengual Miralles, Miguel Sanchez, T. Gros Garcia, L. Guix Font, Mència Benítez, Jaume Francisco‐Pascual, Josep Brugada Terradellas,

Right bundle branch block is one of the most common electrocardiographic abnormalities. Most cases of right bundle branch block are detected in asymptomatic patients in primary care, so a correct interpretation of electrocardiograms (ECGs) at this level is necessary. The objective of this research is to determine the degree of concordance in the diagnosis of incomplete and complete right bundle branch block between four primary care researchers and a cardiologist. The research design is a retrospective ...

Tópico(s): Cardiovascular Syncope and Autonomic Disorders

2019 - Springer Science+Business Media | BMC Family Practice

Artigo Acesso aberto Revisado por pares

William A. Boisvert, David M. Rose, Kristen Johnson, María E. Fuentes, Sérgio A. Lira, Linda K. Curtiss, Robert Terkeltaub,

... lesions. In contrast, our results also reveal that GRO-α and CXCR2 may not be essential for monocyte ingress into early atherosclerotic lesions. LDLR−/− mice backcrossed onto the C57BL/6 background were initially obtained from Jackson Laboratories (Bar Harbor, ME) and were bred at the Scripps Research Institute Animal Facility. Breeding pairs of the CXCR2+/− animals were initially obtained from Genentech (South San Francisco, CA) and bred to generate the CXCR2−/− and ... for detection of leukocyte CXCR2; and anti-KC/GRO-α (R&D Systems, Minneapolis, MN) and anti-mouse MCP-1 (R&D Systems) for the detection of specific murine chemokines. The frozen tissue sections were blocked with 5% normal sera and incubated overnight at 4°C with the primary antibody (1 to 10 μg/ml). The sections were blocked for endogenous peroxidase activity with Peroxo-Block (Zymed, South San Francisco, CA) and incubated with the appropriate secondary antibody ( ...

Tópico(s): Cell Adhesion Molecules Research

2006 - Elsevier BV | American Journal Of Pathology

Revisão Acesso aberto Revisado por pares

Beatriz Gros, Alberto Gómez Pérez, M. Pleguezuelo, Francisco Ruiz, Manuel de la Mata, Manuel Rodríguez‐Perálvarez,

Helicobacter species may cause chronic inflammation of the biliary tract, but its relationship with cancer is controversial. We performed a systematic review and meta-analysis to evaluate the association between Helicobacter species and hepatobiliary tract malignancies. Twenty-six studies (4083 patients) were included in qualitative synthesis, and 18 studies (n = 1895 qualified for meta-analysis. All studies were at high-intermediate risk of bias. Most studies combined several direct microbiological ...

Tópico(s): Cholangiocarcinoma and Gallbladder Cancer Studies

2023 - Multidisciplinary Digital Publishing Institute | Cancers

Artigo Revisado por pares

Víctor Dumar Quintero Castaño, Luís A. Bello‐Pérez, Cristina I. Álvarez‐Barreto, Francisco Javier Castellanos Galeano, Mario E. Rodriguez‐García,

Abstract Banana is a food crop produced extensively in Colombia for fresh consumption. This fruit in the green state has a large amount of starch, which—unlike other Musaceae—has a small granule size that makes it attractive for use in the food industry. This work characterizes physicochemically, morphologically, structurally, and functionally isolated and modified starches from Gros Michel banana. This characterization uses techniques like SEM, XRD, FTIR, DSC, RVA, and HPLC. The results show a ...

Tópico(s): Polysaccharides Composition and Applications

2020 - Wiley | Starch - Stärke

Artigo Revisado por pares

Víctor Dumar Quintero Castaño, JOSE FERNANDO VASCO LEAL, Liceth Cuellar‐Nuñez, Iván Luzardo‐Ocampo, Francisco Javier Castellanos Galeano, Cristina I. Álvarez‐Barreto, Luís A. Bello‐Pérez, Misael Cortés Rodríguez,

Abstract Chemically modified starches from underutilized food sources such as Colombian Musaceae can be combined with additives and proper transformation procedures, as wall materials preserving bioactive compounds. This work aims to find the best conditions for encapsulating blackberry concentrate (BBC) using octenyl succinic anhydride (OSA)‐modified starch from Gros Michel banana (GMB). Experimental designs are conducted to optimize the BBC emulsion and the spray‐drying process. The solubility is ...

Tópico(s): Food composition and properties

2020 - Wiley | Starch - Stärke

Artigo Acesso aberto Revisado por pares

Roch Houot, Emmanuel Bachy, Guillaume Cartron, François‐Xavier Gros, Franck Morschhauser, Lucie Oberic, Thomas Gastinne, Pierre Feugier, Rémy Duléry, Catherine Thiéblemont, Magalie Joris, Francisco Llamas‐Gutierrez, Emmanuel Itti, Cédric Menard, Yassine Al-Tabaa, Clément Bailly, Marie-Hélène Delfau, Camille Laurent, François Lemonnier,

Background Patients with relapsed or refractory (R/R) large B-cell lymphoma (LBCL) after first-line treatment who are unable to undergo high-dose chemotherapy (HDCT) and hematopoietic stem cell transplantation (HSCT) have poor outcomes and limited treatment options. Axicabtagene ciloleucel (axi-cel) has recently demonstrated superiority over standard of care (SOC; salvage chemotherapy followed by HDCT/HSCT in responders) as second-line therapy in patients intended for transplant in the phase 3, ZUMA-7 ...

Tópico(s): Lymphoma Diagnosis and Treatment

2022 - Elsevier BV | Blood

Artigo Acesso aberto Revisado por pares

Roch Houot, Emmanuel Bachy, Guillaume Cartron, François‐Xavier Gros, Franck Morschhauser, Lucie Obéric, Thomas Gastinne, Pierre Feugier, Rémy Duléry, Catherine Thiéblemont, Magalie Joris, Fabrice Jardin, Sylvain Choquet, Olivier Casasnovas, Gabriel Brisou, Morgane Cheminant, Jacques‐Olivier Bay, Francisco Llamas Gutierrez, Cédric Menard, Karin Tarte, Marie-Hélène Delfau, Cédric Portugues, Emmanuel Itti, Xavier Palard-Novello, Paul Blanc‐Durand, Yassine Al Tabaa, Clément Bailly, Camille Laurent, François Lemonnier,

Abstract Axicabtagene ciloleucel (axi-cel) demonstrated superior efficacy compared to standard of care as second-line therapy in patients with high-risk relapsed/refractory (R/R) large B cell lymphoma (LBCL) considered eligible for autologous stem cell transplantation (ASCT); however, in clinical practice, roughly half of patients with R/R LBCL are deemed unsuitable candidates for ASCT. The efficacy of axi-cel remains to be ascertained in transplant-ineligible patients. ALYCANTE, an open-label, phase ...

Tópico(s): Immune Cell Function and Interaction

2023 - Nature Portfolio | Nature Medicine

Artigo Acesso aberto Revisado por pares

Gro Tjalvin, Øistein Svanes, Jannicke Igland, Randi Jacobsen Bertelsen, Bryndís Benediktsdóttir, Shyamali C. Dharmage, Bertil Forsberg, Mathias Holm, Christer Janson, Nils Oskar Jõgi, Ane Johannessen, Andreï Malinovschi, Kathrine Pape, Francisco Gómez Real, Torben Sigsgaard, Kjell Torén, Hilde Kristin Vindenes, Jan‐Paul Zock, Vivi Schlünssen, Cecilie Svanes,

BackgroundEmerging research suggests health effects in offspring after parental chemical exposures before conception. Many future mothers are exposed to potent chemicals at work, but potential offspring health effects are hardly investigated.ObjectiveWe sought to investigate childhood asthma in relation to mother's occupational exposure to cleaning products and disinfectants before conception.MethodsThe multicenter Respiratory Health In Northern Europe/Respiratory Health In Northern Europe, Spain ...

Tópico(s): Asthma and respiratory diseases

2021 - Elsevier BV | Journal of Allergy and Clinical Immunology

Artigo Revisado por pares

Francisco E. Baralle, Eduardo G. Gros,

Tópico(s): Plant Gene Expression Analysis

1969 - Elsevier BV | Phytochemistry

Artigo Acesso aberto

Cristina Tejera Pérez, Ana Chico, Sharona Azriel-Mira, Beatriz Lardiés‐Sánchez, Fernando Gómez-Peralta, Amor Fernández Antonio Jesús, Bartual Rodrigo Amparo, Virginia Bellido, Bellido Guerrero Diego, Botana López Manuel Antonio, Brito Sanfiel Miguel, C. Gloria, Cepero Garcia Daniel, C. Ana, Conget Donlo Ignacio, de Luis Román Daniel Antonio, Durán Martínez María, Duran Rodriguez-Hervada Alejandra, Javier Escaned, F. Carlos, Fernández García Diego, García Fernández Elena, García Jiménez Custodia, Gargallo Fernández Manuel, Gómez Peralta Fernando, González Blanco Cintia, González Clemente José Miguel, González Pérez De Villar Noemí, Gros Herguido Noelia, Hernandez Martinez Antonio Miguel, Herranz Antolin Sandra, Esteban Jódar, Lardiés Sánchez Beatriz, Lecumberri Pascual Edurne, L Martin, López Fernández Judith, López Gallardo Gema, Marco Martinez Amparo, Márquez Pardo Rosa, Merino Torres Juan Francisco, Mezquita Raya Pedro, Mira Sharona, Morales Portillo Cristóbal, M Oscar, Muñoz Torres Manuel, Pablos Velasco Pedro Luis De, Pinés Corrales Pedro José, Quílez Toboso Rosa Pilar, Reyes García Rebeca, Rozas Moreno Pedro, Rodríguez Carnero María Gemma, Tejera Pérez Cristina,

Undoubtedly, technological advances have revolutionised diabetes management in recent years. The development of advanced closed hybrid loop insulin pumps or continuous glucose monitoring (CGM) systems, among others, have increased the quality of life and improved glycaemic control of people with diabetes. However, only some patients have access to such technology, and only some want to use it. CGM has become much more widespread, but in terms of insulin delivery, most people with type 1 diabetes ( ...

Tópico(s): Pancreatic function and diabetes

2023 - Adis, Springer Healthcare | Diabetes Therapy

Artigo Revisado por pares

María José Casanova, Óscar Nantes, Pilar Varela, M Vela-González, Montserrat Rivero, Olivia Sierra‐Gabarda, Sabino Riestra, Manuel Barreiro–de Acosta, M D M Martín-Rodríguez, Carla J. Gargallo-Puyuelo, Cristina Reygosa, Roser Muñoz, Irene García de la Filia‐Molina, Andrea Núñez‐Ortiz, Lilyan Kolle, Margalida Calafat, José María Huguet, E Iglesias-Flores, Teresa Martínez-Pérez, Orencio Bosch, José María Duque‐Alcorta, Santiago Frago‐Larramona, Manuel Van Domselaar, Víctor Manuel González‐Cosano, Luís Bujanda, S Rubio, Alejo Mancebo Mata, Beatriz Castro, Santiago García‐López, Ruth de Francisco, Laura Nieto‐García, Viviana Laredo, Ana Gutiérrez, Francisco Mesonero, Eduardo Leo‐Carnerero, Fiorella Cañete, Lucía Ruiz, Beatriz Gros, María del Moral‐Martínez, Cristina Rodríguez, María Chaparro, Javier P. Gisbert,

Summary Background and Aims Data on the outcomes after switching from adalimumab (ADA) originator to ADA biosimilar are limited. The aim was to compare the treatment persistence, clinical efficacy, and safety outcomes in inflammatory bowel disease patients who maintained ADA originator vs. those who switched to ADA biosimilar. Methods Patients receiving ADA originator who were in clinical remission at standard dose of ADA originator were included. Patients who maintained ADA originator formed the ...

Tópico(s): Microscopic Colitis

2023 - Wiley | Alimentary Pharmacology & Therapeutics

Artigo Acesso aberto Brasil Produção Nacional

Ben M. Sadd, Seth M. Barribeau, Guy Bloch, Dirk C. de Graaf, Peter K. Dearden, Christine G. Elsik, Jürgen Gadau, Cornelis J.P. Grimmelikhuijzen, Martin Hasselmann, Jeffrey D. Lozier, Hugh M. Robertson, Guy Smagghe, Eckart Stolle, Matthias Van Vaerenbergh, Robert M. Waterhouse, Erich Bornberg‐Bauer, Steffen Klasberg, Anna K. Bennett, Francisco Câmara, Roderic Guigó, Katharina J. Hoff, Marco Mariotti, Monica Muñoz‐Torres, Terence D. Murphy, Didac Santesmasses, Gro V. Amdam, Matthew Beckers, Martin Beye, Matthias Biewer, Márcia Maria Gentile Bitondi, Mark Blaxter, Andrew F. G. Bourke, Mark J. F. Brown, Séverine D. Buechel, Rosannah C. Cameron, Kaat Cappelle, James C. Carolan, Olivier Christiaens, Kate L. Ciborowski, David F. Clarke, Thomas J. Colgan, David H. Collins, Andrew G. Cridge, Tamás Dalmay, Stephanie Dreier, Louis du Plessis, Elizabeth J. Duncan, Silvio Erler, Jay D. Evans, Tiago Falcón, Kevin Flores, Flávia Cristina de Paula Freitas, Taro Fuchikawa, Tanja Gempe, Klaus Hartfelder, Frank Hauser, Sophie Helbing, Fernanda C. Humann, Frano Irvine, Lars S. Jermiin, Claire E. Johnson, Reed M. Johnson, Andrew K. Jones, Tatsuhiko Kadowaki, Jonathan Kidner, Vasco Koch, Arian Köhler, Frank Bernhard Kraus, H. Michael G. Lattorff, Megan Leask, Gabrielle A. Lockett, Eamonn B. Mallon, David Santos Marco Antônio, Monika Marxer, Ivan Meeus, Robin F. A. Moritz, Ajay Nair, Kathrin Näpflin, Inga Nissen, Jinzhi Niu, Francis de Morais Franco Nunes, John G. Oakeshott, Amy J. Osborne, Marianne Otte, Daniel Guariz Pinheiro, Nina Rossié, Olav Rueppell, Carolina Gonçalves Santos, Regula Schmid‐Hempel, Björn D. Schmitt, Christina Schulte, Zilá Luz Paulino Simões, Michelle Soares, Luc Swevers, Eva C. Winnebeck, Florian Wolschin, Na Yu, Evgeny M. Zdobnov, Peshtewani Aqrawi, Kerstin P. Blankenburg, Marcus Coyle, Liezl E. Francisco, Álvaro González Hernández, Michael Holder, Matthew E. Hudson, LaRonda Jackson, Joy C. Jayaseelan, Vandita Joshi, Christie Kovar, Sandra L. Lee, Robert Mata, Tittu Mathew, Irene Newsham, Robin Ngo, Geoffrey Okwuonu, Christopher Pham, Ling-Ling Pu, Nehad Saada, Jireh Santibanez, DeNard Simmons, Rebecca Thornton, Aarti Venkat, Kimberly K. O. Walden, Yuanqing Wu, Griet Debyser, Bart Devreese, Claire Asher, Julie Blommaert, Ariel D. Chipman, Lars Chittka, Bertrand Fouks, Jisheng Liu, Meaghan O’Neill, Seirian Sumner, Daniela Puiu, Jiaxin Qu, Steven L. Salzberg, Steven E. Scherer, Donna M. Muzny, Stephen Richards, Gene E. Robinson, Richard A. Gibbs, Paul Schmid‐Hempel, Kim C. Worley,

The shift from solitary to social behavior is one of the major evolutionary transitions. Primitively eusocial bumblebees are uniquely placed to illuminate the evolution of highly eusocial insect societies. Bumblebees are also invaluable natural and agricultural pollinators, and there is widespread concern over recent population declines in some species. High-quality genomic data will inform key aspects of bumblebee biology, including susceptibility to implicated population viability threats.We report ...

Tópico(s): Plant and animal studies

2015 - Springer Science+Business Media | Genome Biology

Artigo Revisado por pares

Ana María Wielandt, C. Milena Villarroel, Elea Gros, Mauricio A. Moreno, Claudia Hurtado, Udo Kronberg, Francisco López-Köstner,

... Citation Format: Ana Maria Wielandt, Cyntia Villarroel, Elea Gros, Mauricio Moreno, Claudia Hurtado, Udo Kronberg, Francisco Lopez-Kostner. Effect of Honokiol and Indol-3- ...

Tópico(s): Free Radicals and Antioxidants

2018 - American Association for Cancer Research | Cancer Research