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Artigo Acesso aberto Revisado por pares

R. Cameron Craddock, Sharad Sikka, Cheung Brian, Ranjeet Khanuja, Ghosh Satrajit, Yan Chaogan, Qingyang Li, Lurie Daniel, Vogelstein Joshua, Burns Randal, Colcombe Stanley, Mennes Maarten, Kelly Clare, Di Martino Adriana, F. Xavier Castellanos, Milham Michael,

... Stanley Colcombe Maarten Mennes Clare Kelly Adriana Di Martino Francisco X Castellanos Michael Milham Google Cameron Craddock Sharad ... Stanley Colcombe Maarten Mennes Clare Kelly Adriana Di Martino Francisco X Castellanos Michael Milham Google Scholar Cameron Craddock ... Stanley Colcombe Maarten Mennes Clare Kelly Adriana Di Martino Francisco X Castellanos Michael Milham PubMed Cameron Craddock Sharad ... Stanley Colcombe Maarten Mennes Clare Kelly Adriana Di Martino Francisco X Castellanos Michael Milham Related Article in Frontiers ...

Tópico(s): Advanced MRI Techniques and Applications

2013 - Frontiers Media | Frontiers in Neuroinformatics

Artigo

FRANCISCO MARTINO SAVING,

... PYELOGRAPHIC TEST FOR RENAL FIXITY DURING RESPIRATION FRANCISCO MARTINO SAVING, FRANCISCO MARTINO SAVING MadridSearch for more papers by this author FRANCISCO MARTINO SAVING, FRANCISCO MARTINO SAVING MadridSearch for more papers by this author ...

Tópico(s): Pediatric Urology and Nephrology Studies

1947 - Wiley | British Journal of Urology

Artigo Acesso aberto Revisado por pares

Negusse Kitaba, Gerd Toril Mørkve Knudsen, Ane Johannessen, Faisal I. Rezwan, Andreï Malinovschi, Anna Oudin, Bryndís Benediktsdóttir, David Martino, Francisco Javier Callejas González, Leopoldo Palacios Gómez, Mathias Holm, Nils Oskar Jõgi, Shyamali C. Dharmage, Svein Magne Skulstad, Sarah Watkins, Matthew Suderman, Francisco Gómez Real, Vivi Schlünssen, Cecilie Svanes, John W. Holloway,

Abstract Background Experimental studies suggest that exposures may impact respiratory health across generations via epigenetic changes transmitted specifically through male germ cells. Studies in humans are, however, limited. We aim to identify epigenetic marks in offspring associated with father’s preconception smoking. Methods We conducted epigenome-wide association studies (EWAS) in the RHINESSA cohort (7–50 years) on father’s any preconception smoking ( n = 875 offspring) and father’s pubertal onset ...

Tópico(s): Child and Adolescent Health

2023 - BioMed Central | Clinical Epigenetics

Artigo Brasil Produção Nacional Revisado por pares

Rodrigo Mologni Gonçalves dos Santos, José Mario De Martino, Francisco Haiter‐Neto, Luís Augusto Pásseri,

The Frankfort horizontal (FH) is a plane that intersects both porions and the left orbitale. However, other combinations of points have also been used to define this plane in 3-dimensional cephalometry. These variations are based on the hypothesis that they do not affect the cephalometric analysis. We investigated the validity of this hypothesis.The material included cone-beam computed tomography data sets of 82 adult subjects with Class I molar relationship. A third-party method of cone-beam computed ...

Tópico(s): Dental Implant Techniques and Outcomes

2017 - Elsevier BV | American Journal of Orthodontics and Dentofacial Orthopedics

Artigo Acesso aberto Brasil Produção Nacional Revisado por pares

Luca Martino, Francisco Louzada,

The Multiple Try Metropolis (MTM) algorithm is an advanced MCMC technique based on drawing and testing several candidates at each iteration of the algorithm. One of them is selected according to certain weights and then it is tested according to a suitable acceptance probability. Clearly, since the computational cost increases as the employed number of tries grows, one expects that the performance of an MTM scheme improves as the number of tries increases, as well. However, there are scenarios where ...

Tópico(s): Integrated Circuits and Semiconductor Failure Analysis

2016 - Springer Science+Business Media | Computational Statistics

Artigo Acesso aberto Revisado por pares

J. Delgado, Jesús Garrido, Luca Lenti, Carlos López Casado, Salvatore Martino, Francisco Javier Cadavid Sierra,

A novel unconventional pseudostatic analysis is proposed here to infer on the sensitivity of a landslide to earthquakes characterized by different physical properties. Several sine waves with different amplitudes, frequencies and phases were applied to the landslide mass assuming limit equilibrium conditions. The unconventional approach was used for the Diezma landslide case study. The landslide is located 25 km from the city of Granada (Spain). Although the slope had repeatedly suffered small-scale ...

Tópico(s): Geotechnical Engineering and Analysis

2014 - Elsevier BV | Engineering Geology

Artigo Brasil Produção Nacional Revisado por pares

Rodrigo Mologni Gonçalves dos Santos, José Mario De Martino, Francisco Haiter‐Neto, Luís Augusto Pásseri,

This article introduces a method that extends the McNamara cephalometric analysis to produce 3-dimensional (3D) measurement values from cone-beam computed tomography images. In the extended method, the cephalometric landmarks are represented by 3D points; the bilateral cephalometric landmarks are identified on both sides of the skull; the cephalometric lines, with the exception of the facial axis, are represented by 3D lines; the cephalometric planes, with the exception of the facial plane, are represented ...

Tópico(s): Temporomandibular Joint Disorders

2018 - Lippincott Williams & Wilkins | Journal of Craniofacial Surgery

Artigo Brasil Produção Nacional Revisado por pares

Rodrigo Mologni Gonçalves dos Santos, José Mario De Martino, Francisco Haiter‐Neto, Luís Augusto Pásseri,

Abstract This study established cone beam computed tomography (CBCT)-based cephalometric norms for Brazilian adults, including the assessment of sexual dimorphism. An observer performed McNamara's cephalometric analysis twice on 60 CBCT datasets acquired from patients with a normal dental occlusion, divided equally into two groups by sex. Welch's t -test was applied to assess differences between the sexes in hard tissue cephalometric measurements, and Dahlberg's formula was used to calculate measurement error ...

Tópico(s): Temporomandibular Joint Disorders

2017 - Elsevier BV | International Journal of Oral and Maxillofacial Surgery

Artigo Revisado por pares

Francesca Martino, Luis Francisco Ávila, José Luis Encinas, A. Luís, Pedro R. Olivares, Luis Lassaletta, Manuel Nistal, Juan A. Tovar,

Tópico(s): Head and Neck Anomalies

2006 - Springer Science+Business Media | Pediatric Surgery International

Artigo Acesso aberto Revisado por pares

Román Martino, Francisco García Ciani, A. R. Paterson, M. Piva,

The effect of lateral confinement due to very close side walls, on erosion caused by a water jet issuing from a rectangular sluice aperture, has been studied experimentally in a narrow laboratory flume. Velocimetry (PIV) in presence of a smooth, no erodible bottom, revealed self-similar velocity profiles with the structure of a wall jet, but upward-shifted with respect to the classical two-dimensional profile. The classical definition of the Shields number was modified, to include the influence of ...

Tópico(s): Soil erosion and sediment transport

2018 - Elsevier BV | European Journal of Mechanics - B/Fluids

Artigo Acesso aberto Brasil Produção Nacional Revisado por pares

Luca Martino, Francisco Louzada,

The adaptive rejection sampling (ARS) algorithm is a universal random generator for drawing samples efficiently from a univariate log-concave target probability density function (pdf). ARS generates independent samples from the target via rejection sampling with high acceptance rates. Indeed, ARS yields a sequence of proposal functions that converge toward the target pdf, so that the probability of accepting a sample approaches one. However, sampling from the proposal pdf becomes more computational ...

Tópico(s): Bayesian Methods and Mixture Models

2017 - Taylor & Francis | Communications in Statistics - Simulation and Computation

Artigo Acesso aberto Revisado por pares

Grzegorz Bilo, Lorenzo Acone, Cecilia Anza‐Ramirez, José Luis Macarlupú, Davide Soranna, Antonella Zambon, Gustavo Vizcardo‐Galindo, Martino F. Pengo, Francisco C. Villafuerte, Gianfranco Parati,

Millions of people worldwide live at high altitude, being chronically exposed to hypobaric hypoxia. Hypertension is a major cardiovascular risk factor but data on its prevalence and determinants in highlanders are limited, and systematic studies with ambulatory blood pressure monitoring are not available. Aim of this study was to assess the prevalence of clinic and ambulatory hypertension and the associated factors in a sample of Andean highlanders. Hypertension prevalence and phenotypes were assessed ...

Tópico(s): Heart Rate Variability and Autonomic Control

2020 - Lippincott Williams & Wilkins | Hypertension

Artigo Brasil Produção Nacional Revisado por pares

Roberto Costa, Kátia Regina da Silva, Roberto Del Valhe Abi Rached, Martino Martinelli Filho, Francisco César Carnevale, Luíz Felipe Pinho Moreira, Noedir Antônio Groppo Stolf,

Background: The incidence of venous lesions following transvenous cardiac device implantation is high. Previous implantation of temporary leads ipsilateral to the permanent devices, and a depressed left ventricular ejection fraction have been associated with an increased risk of venous lesions, though the effects of preventive strategies remain controversial. This randomized trial examined the effects of warfarin in the prevention of these complications in high‐risk patients. Method: Between February ...

Tópico(s): Cardiac Arrhythmias and Treatments

2009 - Wiley | Pacing and Clinical Electrophysiology

Artigo Acesso aberto Brasil Produção Nacional Revisado por pares

Caio Marcos de Moraes Albertini, Katia Regina da Silva, Joaquim Maurício da Motta-Leal-Filho, Elizabeth Sartori Crevelari, Martino Martinelli Filho, Francisco César Carnevale, Roberto Costa,

Background: Venous obstructions are common in patients with transvenous cardiac implantable electronic devices, but they rarely cause immediate clinical problems. The main consequence of these lesions is the difficulty in obtaining venous access for additional leads implantation. Objectives: We aimed to assess the prevalence and predictor factors of venous lesions in patients referred to lead reoperations, and to define the role of preoperative venography in the planning of these procedures. Methods: ...

Tópico(s): Mechanical Circulatory Support Devices

2018 - Sociedade Brasileira de Cardiologia (SBC) | Arquivos Brasileiros de Cardiologia

Artigo Acesso aberto Brasil Produção Nacional Revisado por pares

Afonso Akio Shiozaki, Tiago Senra, Edmundo Arteaga, Cristiane Guedes Pita, Martino Martinelli Filho, Luis Francisco Ávila, José Rodrigues Parga Filho, Charles Mady, Carlos Eduardo Rochitte,

The stratification of risk for sudden death in hypertrophic cardiomyopathy (HCM) continues to be a true challenge due to the great heterogeneity of this disease's presentation, as most individuals remain asymptomatic during their entire lives and others present sudden death as first symptom. Recent studies have suggested that myocardial fibrosis may represent an important substrate for the malignant ventricular arrhythmias, that are responsible for the cases of sudden death related to this disease. ...

Tópico(s): Viral Infections and Immunology Research

2010 - Sociedade Brasileira de Cardiologia (SBC) | Arquivos Brasileiros de Cardiologia

Artigo Acesso aberto Revisado por pares

Francisco Jáñez-Martino, Rocío Aláiz-Rodríguez, V́ıctor González-Castro, Eduardo Fidalgo, Enrique Alegre,

Spam emails are unsolicited, annoying and sometimes harmful messages which may contain malware, phishing or hoaxes. Unlike most studies that address the design of efficient anti-spam filters, we approach the spam email problem from a different and novel perspective. Focusing on the needs of cybersecurity units, we follow a topic-based approach for addressing the classification of spam email into multiple categories. We propose SPEMC-15K-E and SPEMC-15K-S, two novel datasets with approximately 15K ...

Tópico(s): Web Data Mining and Analysis

2023 - Elsevier BV | Applied Soft Computing

Revisão Acesso aberto Revisado por pares

Francisco Jáñez-Martino, Rocío Aláiz-Rodríguez, V́ıctor González-Castro, Eduardo Fidalgo, Enrique Alegre,

Abstract Spam emails have been traditionally seen as just annoying and unsolicited emails containing advertisements, but they increasingly include scams, malware or phishing. In order to ensure the security and integrity for the users, organisations and researchers aim to develop robust filters for spam email detection. Recently, most spam filters based on machine learning algorithms published in academic journals report very high performance, but users are still reporting a rising number of frauds ...

Tópico(s): Internet Traffic Analysis and Secure E-voting

2022 - Springer Science+Business Media | Artificial Intelligence Review

Artigo Acesso aberto Revisado por pares

Deisy Chaves, Eduardo Fidalgo, Enrique Alegre, Rocío Aláiz-Rodríguez, Francisco Jáñez-Martino, George Azzopardi,

Face recognition is a valuable forensic tool for criminal investigators since it certainly helps in identifying individuals in scenarios of criminal activity like fugitives or child sexual abuse. It is, however, a very challenging task as it must be able to handle low-quality images of real world settings and fulfill real time requirements. Deep learning approaches for face detection have proven to be very successful but they require large computation power and processing time. In this work, we ...

Tópico(s): Face and Expression Recognition

2020 - Multidisciplinary Digital Publishing Institute | Sensors

Artigo Acesso aberto Brasil Produção Nacional Revisado por pares

Luca Martino, V́ıctor Elvira, Francisco Louzada,

The Effective Sample Size (ESS) is an important measure of efficiency of Monte Carlo methods such as Markov Chain Monte Carlo (MCMC) and Importance Sampling (IS) techniques. In the IS context, an approximation $\widehat{ESS}$ of the theoretical ESS definition is widely applied, involving the inverse of the sum of the squares of the normalized importance weights. This formula, $\widehat{ESS}$, has become an essential piece within Sequential Monte Carlo (SMC) methods, to assess the convenience of a resampling ...

Tópico(s): Bayesian Methods and Mixture Models

2016 - Elsevier BV | Signal Processing

Artigo Acesso aberto Revisado por pares

Daniel Heestermans Svendsen, Luca Martino, Manuel Campos‐Taberner, Francisco Javier Garcı́a-Haro, Gustau Camps‐Valls,

Solving inverse problems is central in geosciences and remote sensing. The radiative transfer models (RTMs) represent mathematically the physical laws that rule the phenomena in remote sensing applications (forward models). The numerical inversion of the RTM equations is a challenging and computationally demanding problem. For this reason, often the application of a simpler statistical regression is preferred. In general, the regression models predict the biophysical parameter of interest from the ...

Tópico(s): Gaussian Processes and Bayesian Inference

2017 - Institute of Electrical and Electronics Engineers | IEEE Transactions on Geoscience and Remote Sensing

Artigo Acesso aberto

Nicolaus Kröger, José Antonio Pérez‐Simón, Han Myint, Hans Klingemann, Avichai Shimoni, Arnon Nagler, Rodrigo Martino, Adrián Alegre, José Francisco Tomás, Rainer Schwerdtfeger, Michael Kiehl, Axel A. Fauser, Herbert G. Sayer, Ángel León, J. Beyer, Tatjana Zabelina, Francis Ayuk, Jesús F. San Miguel, Ronald Brand, Axel R. Zander,

We evaluated prognostic factors of melphalan/fludarabine-based dose-reduced allografts in patients with multiple myeloma. From 1998 to 2002, 120 patients with multiple myeloma were treated with melphalan/fludarabine followed by allogeneic stem cell transplantation. The cumulative risk at 1 year for treatment-related mortality (TRM) was 18% (95% confidence interval [CI], 12%-28%). In a multivariate analysis, relapse after prior high-dose chemotherapy was the most significant risk factor for TRM (hazard ...

Tópico(s): PI3K/AKT/mTOR signaling in cancer

2004 - Elsevier BV | Biology of Blood and Marrow Transplantation

Artigo Acesso aberto Revisado por pares

José Antonio Pérez‐Simón, Rodrigo Martino, Adrián Alegre, José Francisco Tomás, Ángel León, Dolores Caballero, Ana Sureda, Jordi Sierra, Jesús F. San Miguel,

Summary. The outcome of 29 multiple myeloma patients receiving fludarabine and melphalan‐based non‐myeloablative allogeneic transplant (NMT) was evaluated. Event‐free survival (EFS) at 24 months was 33%, being significantly higher for patients who developed chronic graft‐versus‐host disease (cGVHD) when compared with those who did not [51% vs 0% respectively, P = 0·02; hazard rate = 3·16 (95% confidence interval = 1·09–9·15, P = 0·03)] as well as for patients transplanted in complete remission/partial response ( ...

Tópico(s): PI3K/AKT/mTOR signaling in cancer

2003 - Wiley | British Journal of Haematology

Artigo Acesso aberto Revisado por pares

Joan Gené Badía, Joan Carles Contel Segura, Antonio Hidalgo García, Alícia Borràs-Santos, Montserrat Porta Borges, Anna Oliver Olius, Montse Saus Arus, Carlos Ascaso, Martiño Piñeiro González, Francisco Cegri Lombardo, Esther Limón Ramírez, Antonio Aranzana Martínez, Antonio Heras, Ramón Noguera Rodríguez, Roser Pedret Llaberia, Manuel Borrell Muñoz, Maria Dolors Camprubí Casellas, Jacinto Ortiz Molina, Jaume Martín‐Royo, Susana González Martínez,

To identify which social and health variables are associated with receiving social services in patients included in home care programmes with the implementation of the Dependence Law.Cross-sectional study.72 primary health care teams in Catalonia.Patients over 64 years old with chronic diseases in home care programmes in Catalonia.Health status variables: Charlson, Barthel, Pfeiffer, Braden and Gijon, data from their carer (Zarit), self perception of health (SF-12), health professional visits, as ...

Tópico(s): Geriatric Care and Nursing Homes

2009 - Elsevier BV | Atención Primaria

Artigo Acesso aberto Revisado por pares

Pablo Blanco‐Medina, Eduardo Fidalgo, Enrique Alegre, Roberto A. Vasco-Carofilis, Francisco Jáñez-Martino, Víctor Fidalgo Villar,

Industrial control systems depend heavily on security and monitoring protocols. Several tools are available for this purpose, which scout vulnerabilities and take screenshots of various control panels for later analysis. However, they do not adequately classify images into specific control groups, which is crucial for security-based tasks performed by manual operators. To solve this problem, we propose a pipeline based on deep learning to classify snapshots of industrial control panels into three ...

Tópico(s): Smart Grid Security and Resilience

2021 - Multidisciplinary Digital Publishing Institute | Applied Sciences

Artigo Acesso aberto Revisado por pares

Martino Bardelli, Francisco Zárate-Pérez, Leticia Agúndez, Nelly Jolinon, R. Michael Linden, Carlos Escalante, Els Henckaerts,

Adeno-associated virus (AAV) is a small single-stranded DNA virus that requires the presence of a helper virus, such as adenovirus or herpes virus, to efficiently replicate its genome. AAV DNA is replicated by a rolling-hairpin mechanism (Ward, 2006), and during replication several DNA intermediates can be detected. This detailed protocol describes how to analyze the AAV DNA intermediates formed during AAV replication using a modified Hirt extract (Hirt, 1967) procedure and Southern blotting (Southern, ...

Tópico(s): CRISPR and Genetic Engineering

2017 - American Academy of Arts and Sciences | BIO-PROTOCOL

Artigo Acesso aberto Revisado por pares

Martino Bardelli, Francisco Zárate-Pérez, Leticia Agúndez, R. Michael Linden, Carlos Escalante, Els Henckaerts,

ABSTRACT The life cycle of the human parvovirus adeno-associated virus (AAV) is orchestrated by four Rep proteins. The large Rep proteins, Rep78 and Rep68, are remarkably multifunctional and display a range of biochemical activities, including DNA binding, nicking, and unwinding. Functionally, Rep78 and Rep68 are involved in transcriptional regulation, DNA replication, and genomic integration. Structurally, the Rep proteins share an AAA + domain characteristic of superfamily 3 helicases, with the large ...

Tópico(s): Parvovirus B19 Infection Studies

2016 - American Society for Microbiology | Journal of Virology

Artigo Acesso aberto Brasil Produção Nacional Revisado por pares

Whyara Karoline Almeida da Costa, Larissa Ramalho Brandão, Maria Elena Martino, Estefânia Fernandes Garcia, Adriano Francisco Alves, Evandro Leite de Souza, Jailane de Souza Aquino, Maria Saarela, François Leulier, Hubert Vidal, Marciane Magnani,

Tropical fruit and their industrial processing byproducts have been considered sources of probiotic Lactobacillus. Sixteen tropical fruit-derived Lactobacillus strains were assessed for growth-promoting effects using a host-commensal nutrient scarcity model with Drosophila melanogaster (Dm). Two Lactobacillus strains (L. plantarum 49 and L. plantarum 201) presenting the most significant effects (p ≤ .005) on Dm growth were selected and evaluated for their safety and beneficial effects in adult male Wistar ...

Tópico(s): Enzyme Production and Characterization

2018 - Elsevier BV | Food Research International

Artigo Revisado por pares

Estefanía Martino‐Echarri, Rubén Fernández‐Rodríguez, Francisco Javier Rodríguez‐Baena, Antonio Barrientos‐Durán, Antoni X. Torres‐Collado, María del Carmen Plaza‐Calonge, Suyapa Amador‐Cubero, Javier Cortés, Louise E. Reynolds, Kairbaan Hodivala‐Dilke, Juan Carlos Rodrı́guez-Manzaneque,

The extracellular protease ADAMTS1 (A disintegrin and metalloprotease with thrombospondin repeats 1) has been described as an anti-angiogenic molecule and its role as a putative tumor protective molecule has also been suggested. Here, we have used a tumor xenograft model to determine the role of ADAMTS1 in tumor growth and angiogenesis. Increasing levels of the protease led to the complete inhibition of tumor growth. In an attempt to elucidate the mechanism of action of this protease, we focused ...

Tópico(s): Protease and Inhibitor Mechanisms

2013 - Wiley | International Journal of Cancer