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Artigo Acesso aberto Brasil Produção Nacional Revisado por pares

Gel Roberto Marmitt Berardi, Cármen Lúcia Kuniyoshi Rebelatto, Heloísa F. Tavares, Max Ingberman, Patrícia Shigunov, Fabiane Barchiki, Alessandra Melo de Aguiar, Nelson Itiro Miyague, Júlio César Francisco, Alejandro Correa, Alexandra Cristina Senegaglia, Paula Hansen Suss, J. Moutinho, Vanessa Santos Sotomaior, Lia S. Nakao, Paulo Brofman,

Stem cell therapy has been considered a promise for damaged myocardial tissue. We have previously shown that S-nitroso-N-acetyl-D,L-penicillamine (SNAP) increases the expression of several muscular markers and VEGF in mesenchymal stem cells, indicating that transplantation of SNAP-treated cells could provide better functional outcomes. Here, we transplanted SNAP-treated adipose tissue-derived stem cells (ADSCs) in rat infarcted myocardium. After 30days, we observed a significant improvement of the ...

Tópico(s): Tissue Engineering and Regenerative Medicine

2010 - Elsevier BV | Experimental and Molecular Pathology

Artigo Brasil Produção Nacional Revisado por pares

Jordana Andrioli Salgado, Sthefany Kamile dos Santos, Jesséa de Fátima França Biz, Matheus Borges de Carvalho, Fernanda Rigo, Breno Castello Branco Beirão, Alessandro Francisco Talamini do Amarante, Leandro Batista Costa, Cristina Santos Sotomaior,

This study aimed to evaluate salivary, serum, and abomasal mucus IgA levels in lambs naturally infected with Haemonchus contortus. Thirty-seven crossbred lambs (½ Texel or ½ Ile de France) with an average age of 193 days were evaluated for 56 days after grazing on a contaminated pasture. Fecal samples were collected every 7 days to evaluate the EPG. Blood and saliva samples were collected for IgA measurement every 14 days. On D56, 29 animals were killed for parasite counting and IgA quantification ...

Tópico(s): Parasite Biology and Host Interactions

2022 - Elsevier BV | Research in Veterinary Science

Artigo Acesso aberto Brasil Produção Nacional Revisado por pares

Salmo Raskin, Nasser Allan, Hélio A.G. Teive, Francisco Cardoso, Mônica Santoro Haddad, GILBERTO LEVI, Raquel Boy, JUAN LERENA, Vanessa Santos Sotomaior, M. Janzen-Dück, Laura Bannach Jardim, FLÁVIO R. FELLANDER, LUIZ AUGUSTO FRANCO ANDRADE,

Huntington disease (HD) is associated with expansions of a CAG trinucleotide repeat in the HD gene. Accurate measurement of a specific CAG repeat sequence in the HD gene in 92 Brazilian controls without HD, 44 Brazilian subjects with clinical findings suggestive of HD and 40 individuals from 6 putative HD families, showed a range from 7 to 33 repeats in normal subjects and 39 to 88 repeats in affected subjects. A trend between early age at onset of first symptoms and increasing number of repeats ...

Tópico(s): DNA Repair Mechanisms

2000 - Thieme Medical Publishers (Germany) | Arquivos de Neuro-Psiquiatria