Julie Tomasina, Laurent Poulain, Edwige Abeilard, Florence Giffard, E. Brotin, Ludovic Carduner, Franck Carreiras, Pascal Gauduchon, S. Rault, Aurélie Malzert‐Freon,
We report the development of folate-functionalized nanoparticles able to target folate receptors, and to deliver a poorly water soluble cytotoxic agent, a tripentone, in ovarian carcinoma. The stability under incubation of lipid nanoparticles formulated by a low-energy phase inversion temperature method was investigated. Thanks to the presence of Labrasol(®), a macrogolglyceride into the composition of the nanocarriers, the conjugation of different quantities of a folate derivate (folic acid-polyethylene ...
Tópico(s): Advanced biosensing and bioanalysis techniques
2013 - Elsevier BV | International Journal of Pharmaceutics
... The static dielectric constant of water and the freon R22 (CHClF2) is shown in some detail. Examples ...
Tópico(s): Chemical Thermodynamics and Molecular Structure
1983 - Elsevier BV | Fluid Phase Equilibria