Giles Smith, Andrew Robson, Amanda Andrews, Rosemary Righter, Robert Cole, Alexandra Frean, Gary Duncan, Peter Lansley, Richard Hobson, Alexandra Frean Education Editor, Michael Evans Defence Editor, Jhonti Bird, Philip Howard, Jonny Wilkinson, David Chater, Jeremy Kingston, James Bone, Nigel Sudborough, Penny Wark, Elizabeth Judge, Will Pavia, Sam Marlowe, Marcus Oscarsson, Wendy Ide, Joe Joseph, Andrew Norfolk, Robin Pagnamenta, Richard Kimber, Janie Darling, Ben Webster Transport Correspondent, Pat Gibson, Richard Smith, Donald Hutera, Siobhan Kennedy, Stewart Tendler Crime Correspondent, Feargus O'sullivan, Jack Malvern, Dominic Walsh, Shirley English, Gary Jacob, Dalya Alberge Arts Correspondent, Richard Ford Home Correspondent, Alan Hamilton, Dick Badami, Anatole Kaletsky, Phil Gordon, David Hands, Charles Bremner, Kevin Miller, Adam Sherwin Media Correspondent, Stefanie Marsh, W. Meyer, Matt Dickinson Chief Football Correspondent, Tim Teeman, David Charter, Hugo Rifkind, Derwent May, Russell Kempson, Gary Duncan Economics Editor, Bob Nardelli, Lisa Murphy-O'reilly, Oliver Kay, Gerard Baker, Carola Long, David Lister, Mark Henderson Science Editor, Neil Harman, Christopher Martin-Jenkins, Simon de Bruxelles, Rob Wright, Bernard Lagan, Neil Harman Tennis Correspondent, Raymond Keene, Adam Sage, Christine Buckley, Sean MacAulay, Peter Riddell Political Briefing, Matt Hughes, Rebecca O'Connor, Sarah Birke, Mark Gardner, Christine Buckley Industrial Editor, Chris Campling, Bronwen Maddox, Pam Stockwell, Christopher Martin-Jenkins Chief Cricket Correspondent, Damian Whitworth, Robert Cole Business Commentary, Fran Yeoman Political Reporter, Judith Rowbotham, Roger Boyes, Nick Hasell, Ned Parker, David Hands Rugby Correspondent, Owen Slot Chief Sports Reporter, Kevin Maher, Julian Muscat, Paul Simons, Michael Herman, Nick Szczepanik, James Doran, Tosin Sulaiman, Jane Shilling, Ian Johns, Anthony Browne Chief Political Correspondent, Alice Fordham, Matthew Parris, Mark Bridge, Graham Searjeant Financial Editor, Russell Jenkins, Alan Lee, Joe Eszterhas, Tony Dawe, Allen Robertson, Tom Hennigan, Lucia van der Post, Martin Waller, Catherine Philp, Chris Ayres, Kenneth Williams, Lewis Smith Environment Reporter, Carl Mortished International Business Editor, Peter Janson-Smith, Nigel Hawkes Health Editor, Sarah Butler, Ashling O'Connor, Benedict Nightingale, Oliver Kamm, Angus Batey, Dr Thomas Stuttaford, Stephen Dalton, Walt Gardner, James Christopher, Anthony Clark, Mike Seabrook, Olav Bjortomt, Ross Anderson, Joe Bolger, Bill Frindall, Keith Roberts, Peter Inson,
... Catherine Philp meets the Puerto Rican pin-up Freddy Rodriguez Babel This year it's the march of ...
2007 - Gale Group | TDA
Massimo Volpe, Junren Zhu, Thomas Maxwell, Aldo Rodríguez, Raúl Gamboa, Pablo Gómez-Fernández, Ginés Ortega-Gonzalez, Norberta Matadamas, Freddy Rodríguez, Badal Dass, C.J. Kyle, Laurent Clarysse, Alfonso Bryce, Ernesto Moreno-Heredia, Giuseppe Germanò, Leen Gilles, Ronald D. Smith, John E. Sanderson,
Tópico(s): Sodium Intake and Health
2003 - Elsevier BV | Clinical Therapeutics
Andrew Robson, david wallis, Russell Jenkins, Arthur Leathley and Valerie Elliott, David Adams, Noakes, Richard Whitehead, Nick Nuttall, Portia Colwell, Catherine Riley, Andrew Pierce, James Moore, Patricia Davies, Grace Bradberry, Frances Gibb Legal Editor, Simon Barnes, Gary Neville, Philip Webster and James Landale, Dominic Kennedy and Russell Jenkins, John Morgan, Christopher Somerville, Paul Hoggart, Brian C. Robinson, Mark Souster, R. E. Hodgett, Richard Hobson, Emma Haughton, David Batchelor, Ivo Tennant, Vaugham Freeman, G. s. Keay, Cormac Murphy-O'connor, James Bone, Hugh McGavock, Carl Mortished, Yvonne Thomas, Alian Lee Racing Correspondent, Sharon Linnard, Tony Patrick, Kevin Eason, Sam Lister, Clare Stewart, Thunderer, Andrew Norfolk, Giles Coren, Antonia Senior, Richard Archer, Pat Gibson, David McVay, David McVay and Oliver Kay, Stephen McClarence, Henry Harris, D. R., Steve Keenan, Thrasy Petropoulos, Melanie Tringham, Stewart Tendler Crime Correspondent, David Charter Education Correspondent, Dominic Walsh, Ruth Gledhill, Jerome Boyd Maunsell, Shirley English, Jennal Cox, Bobby Robson, Alix Ramsay Tennis Correspondent, Marianne Walter, Martin Barrow, Brian Roberts, Mark Lunn, June Knowles, Alan Hamilton, Oliver Wright, Mark Inglefield, Rodney Milnes, Michael Backman, Peter Millar, Jenny MacArthur, Andy Enwright, T. P., Nicola Pittam, Lynne O'Donnell, David Hands, P. B., Charles Bremner, Philip Hail, John Fletcher, Peter Barnard, Mile Pattenden, Mark Court, James Urquhart, Russell Kempson, John Nalsh, Mary Gold, Nigel Williamson, Miguel Monjardino, Stephen Anderton, Paul McCann, Amber Cowan, Philip Hall, Patrick Arbuthnot, Mark Henderson Science Correspondent, Christopher Martin-Jenkins, Sally Baker, Suzy Crabtree, Simon de Bruxelles, Jasper rees, Geoffrey Dean, Rob Wright, Christina Koning, Adrian Potts, Raymond Keene, Adam Sage, David Robinson, Ray Mullaney, Clive Mathieson, Matthew Pryor, Matt Dickinson, Roy C. Allison, Lucy Pinney, James Allcock, Christine Buckley Industrial Editor, G. S., Francis Gilbert, Min Cooper, Nigel Hawkes, Christopher Walker Chief Ireland Correspondent, Chris Ayres Media Business Correspondent, Richard Owen, Shane Warne, William Heard, Damian Whitworth, Helen Nugent, Marcel Berlins, Sarah Litvinoff, John Stern, Oliver August, Nick Hasell, Tom Baldwin and Philip Webster, Stewart Tendler, John King, David Hands Rugby Correspondent, Charles Pinney, Martin Fletcher European Correspondent, Suzanne Marriott, Mark Court and Roland Watson, Anne Ashworth, John Goodbody, James Doran, Giles Whittell, Danny Lee, Michael Bennett, Alex O'Connell, Paul McCann Media Correspondent, Matthew Parris, Della Mannix, Jennai Cox, Adrian potts, Chloe Bryan-Brown and Steve Keenan, Mark Hodkinson, Chris McGrath, Melissa Kite Political Reporter, Tim Wapshott, Michael Austin, Alan Lee, Denis Cashman, Jane Owen, Walter Gammie, Ben MacIntyre, Giulio Sica, Jeremy Hart, Sasha Slater, Michael Dynes, Richard Miles, John Naish, Marcus Braybrooke, Geoffrey Rowell, Tim Jones, D. Rowe, Mark Henderson, Martin Waller, Chris Ayres, Danny Baker, Lesley MacDONAGH, Fran Littlewood, Stewart Tendler Crime Correspondent and Andrew Norfolk, David Powell, Jack Bailey, Sam Kiley, Tom Chesshyre, Elizabeth Buchan, Valerie Grove, John Phillips, Jan Godfrey, Sally Patten, Susie Steiner, Penny Perrick, Conal Gregory, Nick Baty, jo henderson, Scott Bradfield, Edward Gorman Sailing Correspondent, Walter Ellis, Alan Wild, Patience Wheatcroft, Christopher Irvine, Chloe Bryan-Brown, Susan Emmett,
... Advertising Items Classical Earthly Delights Alexander Chaushian and Freddy Kempf Dorothea Roschmann and Akademie Fur Alte Musik… ...
2000 - Gale Group | TDA
Josep Domingo‐Ferrer, Anna Oganian, Ángel Freddy Rodríguez Torres, Josep M. Mateo‐Sanz,
Microaggregation is a statistical disclosure control technique. Raw microdata (i.e. individual records) are grouped into small aggregates prior to publication. With fixed-size groups, each aggregate contains k records to prevent disclosure of individual information. Individual ranking is a usual criterion to reduce multivariate microaggregation to univariate case: the idea is to perform microaggregation independently for each variable in the record. Using distributional assumptions, we show in this ...
Tópico(s): Privacy-Preserving Technologies in Data
2002 - World Scientific | International Journal of Uncertainty Fuzziness and Knowledge-Based Systems
Carl Henrik Langebaek Rueda, Alejandra Gonzales, Lucero Aristizábal, Marcela Bernal Arévalo, María Antonieta Corcione, Luisa Fernanda Mendoza, L.E. Altamirano Pérez, Freddy Rodríguez, Catalina Zorro,
This paper studies the relation between feasts and other issues that are traditionally related the power of Muisca chiefs in their communities. The research question deals with the linkage between different dimensions of the social stratification in the the Muisca site of Tibanica, including: feasting itself, health, kinship and nutrition. It is argued that there is no lineal relation between such variables, and that Muisca social organization is best understood from a multidimensional and comparative ...
Tópico(s): History and Politics in Latin America
2015 - Colombian Institute of Anthropology and History | Revista Colombiana de Antropología
Wei Chen, Anupama Tuladhar, Shantelle Rolle, Yanhao Lai, Freddy Rodriguez del Rey, Cristian Zavala, Yuan Liu, Kathleen S. Rein,
Karenia brevis, the Florida red tide dinoflagellate produces a suite of neurotoxins known as the brevetoxins. The most abundant of the brevetoxins PbTx-2, was found to inhibit the thioredoxin-thioredoxin reductase system, whereas the PbTx-3 has no effect on this system. On the other hand, PbTx-2 activates the reduction of small disulfides such as 5,5′-dithio-bis-(2-nitrobenzoic acid) by thioredoxin reductase. PbTx-2 has an α, β-unsaturated aldehyde moiety which functions as an efficient electrophile ...
Tópico(s): Electron Spin Resonance Studies
2017 - Elsevier BV | Toxicology and Applied Pharmacology
Richar Jacobo Posso Pacheco, Laura Cristina Barba Miranda, Ángel Freddy Rodríguez Torres, Luis Fernando Xavier Núñez Sotomayor, Carlos Efrén Ávila-Quinga, Pablo Anthony Rendón Morales,
This article aimed to describe a microcurricular learning model of Physical Education; the description was based on a bibliographic review of 33 academic texts resulting from the process of inclusion and exclusion criteria. This process was framed in a publication period corresponding to 1994 until 2020, from the Dialnet, Google Scholar databases, and the platform of the Ministry of Education of Ecuador. Four dimensions were analyzed: Ecuadorian Physical Education Curriculum, curricular approaches, ...
Tópico(s): Various Academic Research Studies
2020 - National University, Costa Rica | Revista Electrónica Educare
Norman Toro, Freddy Rodríguez, Anyelo Rojas, Pedro Robles, Yousef Ghorbani,
The accelerated growth in global demand for Manganese coincides with the continuing depletion of high-grade ores on the earth's surface. This element is essential for diverse markets such as steel production, dietary additives, fertilizers, cells, fine chemicals, and some chemical reagents. Interestingly, there are large mineral reserves in the ocean's depths, where marine nodules are an attractive option due to their high manganese content (between 16 and 24%). The dissolution of MnO2 from manganese ...
Tópico(s): Radioactive element chemistry and processing
2021 - Elsevier BV | Minerals Engineering
Freddy Rodríguez, C. Moraga, Jonathan Castillo, Edelmira D. Gálvez, Pedro Robles, Norman Toro,
This review aims to understand the environmental impact that tailings produce on the land and marine ecosystem. Issues related to flora, fauna, and the environment are revised. In the first instance, the origin of the treatment and disposal of marine mining waste in Chile and other countries is studied. The importance of tailings’ valuable elements is analyzed through mineralogy, chemical composition, and oceanographic interactions. Several tailings’ treatments seek to recover valuable minerals ...
Tópico(s): Mine drainage and remediation techniques
2021 - Multidisciplinary Digital Publishing Institute | Metals
Produção Nacional
Revisado por pares
Ángel Freddy Rodríguez Torres, Margarita Angélica Medina Nicolalde, Daniel Alejandro Tapia Medina, Joselyn Carolina Rodríguez Alvear,
El objetivo del estudio fue realizar una revisión bibliográfica sobre el impacto que tiene la formación docente en el proceso de cambio e innovación en la educación. Esta investigación se fundamentó en la técnica de análisis documental para lo cual se utilizó varias bases de datos como Google Académico, Dialnet, Redalyc y Scielo guiados con las palabras clave Innovación educativa, cambio, innovación y educational innovation, educational change, innovation, donde se revisaron y seleccionaron 150 ...
Tópico(s): Educational Methods and Psychological Studies
2022 - University of Zulia | Revista Venezolana de Gerencia
Wei Chen, Ricardo Colon, J. William Louda, Freddy Rodriguez del Rey, Michaella Durham, Kathleen S. Rein,
The Florida red tide dinoflagellate, Karenia brevis, is the major harmful algal bloom dinoflagellate of the Gulf of Mexico and plays a destructive role in the region. Blooms of K. brevis can produce brevetoxins: ladder-shaped polyether (LSP) compounds, which can lead to adverse human health effects, such as reduced respiratory function through inhalation exposure, or neurotoxic shellfish poisoning through consumption of contaminated shellfish. The endogenous role of the brevetoxins remains uncertain. ...
Tópico(s): Environmental Toxicology and Ecotoxicology
2018 - Elsevier BV | Harmful Algae
Ángel Freddy Rodríguez Torres, Margarita Angélica Medina Nicolalde, Daniel Alejandro Tapia Medina,
El docente es un factor fundamental en la calidad de la educación y responsable de lograr un aprendizaje auténtico en los estudiantes. El profesorado novel universitario que ingresa a trabajar en la institución de educación superior cuenta con una sólida formación académica, por lo requiere apoyo en lo personal y profesional y brinde una enseñanza de calidad. El objetivo del estudio es analizar la incidencia de la inducción del profesorado novel en la mejora de su desempeño profesional, para lo ...
Tópico(s): Educational Methods and Psychological Studies
2020 - | Revista EDUCARE - UPEL-IPB - Segunda Nueva Etapa 2 0
Gunnar Boysen, Rashi Arora, Amanda Degner, Karin R. Vevang, Christopher Chao, Freddys Rodriguez, Scott J. Walmsley, Luke Erber, Natalia Tretyakova, Lisa A. Peterson,
Smoking is a leading cause of lung cancer, accounting for 81% of lung cancer cases. Tobacco smoke contains over 5000 compounds, of which more than 70 have been classified as human carcinogens. Of the many tobacco smoke constituents, 1,3-butadiene (BD) has a high cancer risk index due to its tumorigenic potency and its abundance in cigarette smoke. The carcinogenicity of BD has been attributed to the formation of several epoxide metabolites, of which 1,2,3,4-diepoxybutane (DEB) is the most toxic and ...
Tópico(s): Genomics, phytochemicals, and oxidative stress
2020 - American Chemical Society | Chemical Research in Toxicology
Griangsak Chairote, Freddy Gutiérrez Rodríguez, J. Crouzet,
ABSTRACT The volatile components of apricot variety “Rouge du Roussillon” were isolated by vacuum distillation and fractionated on silica gel. Analysis by combined gas chromatography‐mass spectrometry led to identification of several compounds identified for the first time from this product. These compounds included p‐hydroxybenzaldehyde, p‐methoxybenzaldehyde, (3‐phenyl propyl)‐propyl or isopropyl ketone, 3‐nonene‐2‐one, damascenone, β‐ionone, dihydroactinidiolide, 2‐phenylethanol, cis rose oxide ...
Tópico(s): Advanced Chemical Sensor Technologies
1981 - Wiley | Journal of Food Science
Yenny Martínez Díaz, Gina Vanegas Laverde, Luis Reina Gamba, Humberto Mayorga, Catalina Arévalo-Ferro, Freddy Ramos Rodríguez, Carmenza Duque Beltrán, Leonardo Castellanos,
Biofilm has a primary role in the pathogenesis of diseases and in the attachment of multicellular organisms to a fouled surface. Because of that, the control of bacterial biofilms has been identified as an important target. In the present study, five lipid compounds isolated from soft coral Eunicea sp. and three terpenoids together with a mixture of sterols from Eunicea fusca collected at the Colombian Caribbean Sea showed different effectiveness against biofilm formation by three marine bacteria ...
Tópico(s): Bacterial biofilms and quorum sensing
2015 - Springer Science+Business Media | Revista Brasileira de Farmacognosia
Rob Driessen, Oscar M. J. A. Stassen, Marika Sjöqvist, Freddy Suarez Rodriguez, Janine Grolleman, Carlijn V. C. Bouten, Cecilia Sahlgren,
Shear stress induces a ligand specific Jagged1 response and enhanced signal sending potential in endothelial cells.
Tópico(s): Hippo pathway signaling and YAP/TAZ
2018 - Oxford University Press | Integrative Biology
Je-Ruei Wen, Benjamin J. Roman, Freddy A. Rodríguez Ortiz, Noel Mireles Villegas, Nicholas Porcellino, Matthew Sheldon,
Lack of detailed understanding of the growth mechanism of CsPbBr3 nanocrystals has hindered sophisticated morphological and chemical control of this important emerging optoelectronic material. Here, we have elucidated the growth mechanism by slowing the reaction kinetics. When 1-bromohexane is used as an alternative halide source, bromide is slowly released into the reaction mixture, extending the reaction time from ∼3 s to greater than 20 min. This enables us to monitor the phase evolution of products ...
Tópico(s): Solid-state spectroscopy and crystallography
2019 - American Chemical Society | Chemistry of Materials
Nicole C. A. van Engeland, Freddy Suarez Rodriguez, Adolfo Rivero‐Müller, Tommaso Ristori, Camille L. Duran, Oscar M. J. A. Stassen, Daniel Antfolk, Rob Driessen, Saku Ruohonen, Suvi T. Ruohonen, Salla Nuutinen, Eriika Savontaus, Sandra Loerakker, Kayla J. Bayless, Marika Sjöqvist, Carlijn V. C. Bouten, John Eriksson, Cecilia Sahlgren,
Abstract The intermediate filament (IF) cytoskeleton has been proposed to regulate morphogenic processes by integrating the cell fate signaling machinery with mechanical cues. Signaling between endothelial cells (ECs) and vascular smooth muscle cells (VSMCs) through the Notch pathway regulates arterial remodeling in response to changes in blood flow. Here we show that the IF-protein vimentin regulates Notch signaling strength and arterial remodeling in response to hemodynamic forces. Vimentin is important ...
Tópico(s): Skin and Cellular Biology Research
2019 - Nature Portfolio | Scientific Reports
Freddy A. Rodríguez Ortiz, Benjamin J. Roman, Je-Ruei Wen, Noel Mireles Villegas, David F. Dacres, Matthew Sheldon,
Here, we report that the oxidation state of gold plays a dominant role in determining the reaction products when gold halide salts are mixed with all-inorganic lead halide perovskite nanocrystals. When CsPbX3 nanocrystals react with Au(i) halide salts, Au nanoparticles are deposited on the surface of the perovskites through the reduction of Au1+ ions by the surfactant ligand shell, to produce Au-CsPbX3 heterostructures. These heterostructures preserve comparably high photoluminescence quantum yield ( ...
Tópico(s): Chalcogenide Semiconductor Thin Films
2019 - Royal Society of Chemistry | Nanoscale
Marika Sjöqvist, Daniel Antfolk, Freddy Suarez Rodriguez, Cecilia Sahlgren,
During the last decades intermediate filaments (IFs) have emerged as important regulators of cellular signaling events, ascribing IFs with functions beyond the structural support they provide. The organ and developmental stage-specific expression of IFs regulate cell differentiation within developing or remodeling tissues. Lack of IFs causes perturbed stem cell differentiation in vasculature, intestine, nervous system, and mammary gland, in transgenic mouse models. The aberrant cell fate decisions ...
Tópico(s): Wnt/β-catenin signaling in development and cancer
2020 - Wiley | The FASEB Journal
Jenna L. Miller, Jean‐Marc Lawrence, Freddy O. Rodriguez del Rey, Paul E. Floreancig,
Organic oxidants, including quinones, oxoammonium ions, and trityl cations, abstract hydride ions to form carbocations. This review describes the mechanistic foundations for these processes and the vast array of their applications in synthesis.
Tópico(s): Catalytic Cross-Coupling Reactions
2022 - Royal Society of Chemistry | Chemical Society Reviews
Je-Ruei Wen, Freddy A. Rodríguez Ortiz, Anna Champ, Matthew Sheldon,
The fast kinetics of all-inorganic CsPbX3 (X = Cl, Br, or I) nanocrystal growth entail that many synthetic strategies for structural control established in other semiconductor systems do not apply. Rather, products are often determined by thermodynamic factors, limiting the range of synthetic outcomes and functionality. In this study, we show how reaction kinetics are significantly slowed if nanocrystals are prepared using a dual injection strategy that moderates the crucial interaction between cesium ...
Tópico(s): Chalcogenide Semiconductor Thin Films
2022 - American Chemical Society | ACS Nano
Miguel Delgado, Freddy Rodríguez, Kalina Kassadjikova, Lars Fehren‐Schmitz,
On the basis of distinct lines of evidence, detailed reconstructions of the Holocene population history of the Sabana de Bogotá (SB) region, Northern South America, have been performed. Currently, there exist two competing models that support temporal continuity or, alternatively, divergence. Despite recent bioarchaeological and isotopic research that lends support to the population discontinuity model, several discrepancies remain, calling for other kinds of evidences to be explored for a more detailed ...
Tópico(s): Archaeology and ancient environmental studies
2020 - Elsevier BV | Quaternary International
Freddy Suarez Rodriguez, Sami Şanlıdağ, Cecilia Sahlgren,
The mechanical regulation of Notch signaling is an emerging area of interest in cell biology. Notch is essential in many physiological processes in which mechanical stress plays an important role. This review provides an overview of the mechanoregulation of Notch signaling in multiple steps of the pathway. First, we discuss the current knowledge on the direct mechanoregulation of Notch receptor maturation and localization to the membrane and the effect of mechanical stress on the Notch components. ...
Tópico(s): RNA Research and Splicing
2023 - Elsevier BV | Current Opinion in Cell Biology
Manuel Saldaña, Freddy Rodríguez, Anyelo Rojas, Kevin Pérez, Palma Angulo,
Multivariate models are a useful tool when studying the effects of independent variables on one or more dependent variables, since this approach allows modeling of the dynamics of complex systems based on simple analytical models with considerable certainty. Due to the decrease in the copper oxide mineral grades, leaching of copper sulfide minerals (secondary sulfides) has positioned itself as a benchmark of operation for the Chilean mining industry. The present work proposes the study of the effects ...
Tópico(s): Mineral Processing and Grinding
2020 - Association of Chemical Engineers of Serbia | Hemijska industrija
Lina Mariana Tovar, Carlos F. Burgos, Gonzalo E. Yévenes, Gustavo Moraga‐Cid, Jorge Fuentealba, Claudio Coddou, Luisa Bascuñán‐Godoy, Claudio Catrupay, Ángel Freddy Rodríguez Torres, Patricio A. Castro,
Neurulation is a crucial process in the formation of the central nervous system (CNS), which begins with the folding and fusion of the neural plate, leading to the generation of the neural tube and subsequent development of the brain and spinal cord. Environmental and genetic factors that interfere with the neurulation process promote neural tube defects (NTDs). Connexins (Cxs) are transmembrane proteins that form gap junctions (GJs) and hemichannels (HCs) in vertebrates, allowing cell-cell (GJ) or paracrine ( ...
Tópico(s): Neuroscience of respiration and sleep
2023 - Multidisciplinary Digital Publishing Institute | International Journal of Molecular Sciences
María Carmen Pegalajar Palomino, Ángel Freddy Rodríguez Torres,
<p>En la actualidad es importante el desarrollo de competencias digitales en el estudiante universitario que se prepara para docente y pueda participar en una sociedad digital. El estudio analiza el nivel de dominio de las competencias digitales del estudiante universitario de Ecuador. La investigación es de tipo descriptivo y se administró un cuestionario (n=778). Los resultados revelan que el estudiante da prioridad a la investigación y el manejo de información, presentando dificultades en ...
Tópico(s): Education and Teacher Training
2023 - | Campus Virtuales
Jenna Thomforde, Iwen Fu, Freddys Rodriguez, Suresh S. Pujari, Suse Broyde, Natalia Tretyakova,
DNA–protein cross-links (DPCs) are unusually bulky DNA lesions that form when cellular proteins become trapped on DNA following exposure to ultraviolet light, free radicals, aldehydes, and transition metals. DPCs can also form endogenously when naturally occurring epigenetic marks [5-formyl cytosine (5fC)] in DNA react with lysine and arginine residues of histones to form Schiff base conjugates. Our previous studies revealed that DPCs inhibit DNA replication and transcription but can undergo proteolytic ...
Tópico(s): Epigenetics and DNA Methylation
2021 - American Chemical Society | Biochemistry
Freddy O. Rodriguez del Rey, Paul E. Floreancig,
Re2O7 in hexafluoroisopropyl alcohol provides access to cationic intermediates from alcohols through the intermediacy of perrhenate esters. This manuscript describes the application of the system to the formation of a number of weakly basic heterocyclic systems through dehydration reactions and intramolecular nucleophilic addition. The influence of the substrate structure on the reaction rates and stereocontrol is discussed with respect to intermediate ion pairs.
Tópico(s): Asymmetric Synthesis and Catalysis
2020 - American Chemical Society | Organic Letters
Ana Cristina Chirinos Martínez, Rubén Ulises Perozo Martín, Freddy Rodríguez Acasio,
Recibido: 19 de diciembre del 2018Aprobado: 01 de febrero del 2019Se analizan los perfiles gerenciales de las organizaciones vinculadas a un entorno dinámico, competitivo bajo un clima de incertidumbre. La investigación documental-descriptiva refleja la teoría de las organizaciones, comportamientos y conductas resultado de la interacción entre los individuos de las mismas. Los perfiles son alusivos a imágenes organizacionales con modos lineales y mecánicos de pensar, sentir y actuar. Así como, a ...
Tópico(s): Diverse Applied Research Studies
2019 - | Revista Arbitrada Interdisciplinaria Koinonía