Hans Lecher, Fritz Graf, Claus Heuck, Karl Köberle, Fritz Gnädinger, Fritz Heydweiller,
... for more papers by this authorKarl Köberle, Karl Köberle Chemisches Laboratorium der Universität Freiburg I. B.Search for more papers by this authorFritz Gnädinger, Fritz Gnädinger Chemisches Laboratorium der Universität Freiburg I. B. ... for more papers by this authorKarl Köberle, Karl Köberle Chemisches Laboratorium der Universität Freiburg I. B.Search for more papers by this authorFritz Gnädinger, Fritz Gnädinger Chemisches Laboratorium der Universität Freiburg I. B. ...
Tópico(s): History and advancements in chemistry
1925 - Wiley | Justus Liebig s Annalen der Chemie
Anamaria Brozović, Lidija Vuković, Darija Stupin Polančac, István Arany, Beate Köberle, Gerhard Fritz, Željka Fiket, Dragomira Majhen, Andreja Ambriović‐Ristov, Maja Osmak,
The major obstacle of successful tumor treatment with carboplatin (CBP) is the development of drug resistance. In the present study, we found that following treatment with CBP the amount of platinum which enters the human laryngeal carcinoma (HEp2)-derived CBP-resistant (7T) cells is reduced relative to the parental HEp2. As a consequence, the formation of reactive oxidative species (ROS) is reduced, the induction of endoplasmic reticulum (ER) stress is diminished, the amount of inter- and intrastrand ...
Tópico(s): Autophagy in Disease and Therapy
2013 - Public Library of Science | PLoS ONE

... studies on denervation conducted in Ribeirão Preto by Fritz Köberle starting in the 1950 decade led to a ...
Tópico(s): Trypanosoma species research and implications
1999 - Instituto Oswaldo Cruz, Ministério da Saúde | Memórias do Instituto Oswaldo Cruz

Tópico(s): Medical History and Research
2025 - Brazilian Society of Tropical Medicine | Revista da Sociedade Brasileira de Medicina Tropical
Tópico(s): Public Administration and Political Analysis
1998 - Karlsruhe Institute of Technology, Institute for Technology Assessment and Systems Analysis (ITAS) | TATuP Zeitschrift für Technikfolgenabschätzung in Theorie und Praxis
René Spiegel, Fritz Huber, S. Köberle,
A long‐term clinical comparison of the effects of ergoloid mesylates and placebo on 148 healthy elderly volunteers of both sexes was analyzed after three years of study. At that point, 99 subjects (53 receiving ergoloid mesylates and 46, placebo) were still being treated under double‐blind conditions, while the remainder either had dropped out or continued to participate under open conditions. Many subjects in both groups were healthier after the three years than they had been at the onset of the ...
Tópico(s): Cholinesterase and Neurodegenerative Diseases
1983 - Wiley | Journal of the American Geriatrics Society
Martin Köberle, Annegret Klein-Günther, Monika Schütz, Michaela Fritz, Susanne Berchtold, Eva Tolosa, Ingo B. Autenrieth, Erwin Bohn,
Yersinia enterocolitica (Ye) evades the immune system of the host by injection of Yersinia outer proteins (Yops) via a type three secretion system into host cells. In this study, a reporter system comprising a YopE-beta-lactamase hybrid protein and a fluorescent staining sensitive to beta-lactamase cleavage was used to track Yop injection in cell culture and in an experimental Ye mouse infection model. Experiments with GD25, GD25-beta1A, and HeLa cells demonstrated that beta1-integrins and RhoGTPases ...
Tópico(s): Plant-based Medicinal Research
2009 - Public Library of Science | PLoS Pathogens
Lars Helbig, Julia Damrot, Johannes Hülsenbeck, Beate Köberle, Anamaria Brozović, Maja Osmak, Željka Fiket, Bernd Kaina, Gerhard Fritz,
Although stress-activated protein kinases/c-Jun N-terminal kinases (SAPK/JNK) are rapidly activated by genotoxins, the role of DNA damage in this response is not well defined. Here we show that the SEK1/MKK4-mediated dual phosphorylation of SAPK/JNK (Thr-183/Tyr-185) correlates with the level of cisplatin-DNA adducts at late times (16-24 h) after drug treatment in both human and mouse cells. Transfection of platinated plasmid DNA also caused SAPK/JNK activation. A defect in transcription-coupled nucleotide ...
Tópico(s): Effects of Radiation Exposure
2011 - Elsevier BV | Journal of Biological Chemistry
Hans Lecher, F. W. Holschneider, Karl Köberle, Walter Speer, Paul Stöcklin,
... Search for more papers by this authorFritz Holschneider, Fritz Holschneider Chem. Laborat. d. Universität Freiburg i. B.Search for more papers by this authorKarl Köberle, Karl Köberle Chem. Laborat. d. Universität Freiburg i. ... Search for more papers by this authorFritz Holschneider, Fritz Holschneider Chem. Laborat. d. Universität Freiburg i. B.Search for more papers by this authorKarl Köberle, Karl Köberle Chem. Laborat. d. Universität Freiburg i. ...
Tópico(s): Axial and Atropisomeric Chirality Synthesis
1925 - Wiley | Berichte der Deutschen Chemischen Gesellschaft. Abteilung B, Abhandlungen
Thomas M. Rünger, Steffen Emmert, Dirk Schadendorf, Caroline Diem, Bernd Epe, Doris Hellfritsch,
... group A protein in testicular germ cell tumors (Koberle et al., 1999Koberle B. Masters J.R. Hartley ...
Tópico(s): Cancer Genomics and Diagnostics
2000 - Elsevier BV | Journal of Investigative Dermatology
Deborah M. Anderson, Nancy Ciletti, Hanni Lee-Lewis, Derek Elli, Joshua Segal, Kristin L. DeBord, Katie A. Overheim, Maria Tretiakova, Robert R. Brubaker, Olaf Schneewind,
... 5131Crossref PubMed Scopus (61) Google Scholar, 34Adkins I Koberle M Grobner S Bohn E Autenrieth I Borgmann ...
Tópico(s): Zoonotic diseases and public health
2009 - Elsevier BV | American Journal Of Pathology
... 5: 1428-1432PubMed Google Scholar), cirrhosis (13Waidmann O. Koberle V. Brunner F. Zeuzem S. Piiper A. Kronenberger ...
Tópico(s): RNA modifications and cancer
2013 - Elsevier BV | Journal of Lipid Research
... today offer religious interpretation is shown by Adolf Köberle’s Bach, Beethoven, Bruckner (Tübingen, 1947). Also the ... Profundis, p. 373.Jochen Klepper, Gedichte, ed. by Fritz Wenzel (Berlin, 1947), p. 21.Published in a ...
Tópico(s): Literature and Cultural Memory
1949 - Routledge | The Germanic Review Literature Culture Theory