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Artigo

Hans Lecher, Fritz Graf, Claus Heuck, Karl Köberle, Fritz Gnädinger, Fritz Heydweiller,

... for more papers by this authorKarl Köberle, Karl Köberle Chemisches Laboratorium der Universität Freiburg I. B.Search for more papers by this authorFritz Gnädinger, Fritz Gnädinger Chemisches Laboratorium der Universität Freiburg I. B. ... for more papers by this authorKarl Köberle, Karl Köberle Chemisches Laboratorium der Universität Freiburg I. B.Search for more papers by this authorFritz Gnädinger, Fritz Gnädinger Chemisches Laboratorium der Universität Freiburg I. B. ...

Tópico(s): History and advancements in chemistry

1925 - Wiley | Justus Liebig s Annalen der Chemie

Artigo Acesso aberto Revisado por pares

Anamaria Brozović, Lidija Vuković, Darija Stupin Polančac, István Arany, Beate Köberle, Gerhard Fritz, Željka Fiket, Dragomira Majhen, Andreja Ambriović‐Ristov, Maja Osmak,

The major obstacle of successful tumor treatment with carboplatin (CBP) is the development of drug resistance. In the present study, we found that following treatment with CBP the amount of platinum which enters the human laryngeal carcinoma (HEp2)-derived CBP-resistant (7T) cells is reduced relative to the parental HEp2. As a consequence, the formation of reactive oxidative species (ROS) is reduced, the induction of endoplasmic reticulum (ER) stress is diminished, the amount of inter- and intrastrand ...

Tópico(s): Autophagy in Disease and Therapy

2013 - Public Library of Science | PLoS ONE

Artigo Acesso aberto Brasil Produção Nacional Revisado por pares

Áluízio Prata,

... studies on denervation conducted in Ribeirão Preto by Fritz Köberle starting in the 1950 decade led to a ...

Tópico(s): Trypanosoma species research and implications

1999 - Instituto Oswaldo Cruz, Ministério da Saúde | Memórias do Instituto Oswaldo Cruz

Carta Acesso aberto Brasil Produção Nacional Revisado por pares

Luiz Eduardo Correia Miranda,

Tópico(s): Medical History and Research

2025 - Brazilian Society of Tropical Medicine | Revista da Sociedade Brasileira de Medicina Tropical

Artigo Acesso aberto

TATuP Redaktion,

Tópico(s): Public Administration and Political Analysis

1998 - Karlsruhe Institute of Technology, Institute for Technology Assessment and Systems Analysis (ITAS) | TATuP Zeitschrift für Technikfolgenabschätzung in Theorie und Praxis

Artigo Revisado por pares

René Spiegel, Fritz Huber, S. Köberle,

A long‐term clinical comparison of the effects of ergoloid mesylates and placebo on 148 healthy elderly volunteers of both sexes was analyzed after three years of study. At that point, 99 subjects (53 receiving ergoloid mesylates and 46, placebo) were still being treated under double‐blind conditions, while the remainder either had dropped out or continued to participate under open conditions. Many subjects in both groups were healthier after the three years than they had been at the onset of the ...

Tópico(s): Cholinesterase and Neurodegenerative Diseases

1983 - Wiley | Journal of the American Geriatrics Society

Artigo Acesso aberto Revisado por pares

Martin Köberle, Annegret Klein-Günther, Monika Schütz, Michaela Fritz, Susanne Berchtold, Eva Tolosa, Ingo B. Autenrieth, Erwin Bohn,

Yersinia enterocolitica (Ye) evades the immune system of the host by injection of Yersinia outer proteins (Yops) via a type three secretion system into host cells. In this study, a reporter system comprising a YopE-beta-lactamase hybrid protein and a fluorescent staining sensitive to beta-lactamase cleavage was used to track Yop injection in cell culture and in an experimental Ye mouse infection model. Experiments with GD25, GD25-beta1A, and HeLa cells demonstrated that beta1-integrins and RhoGTPases ...

Tópico(s): Plant-based Medicinal Research

2009 - Public Library of Science | PLoS Pathogens

Artigo Acesso aberto Revisado por pares

Lars Helbig, Julia Damrot, Johannes Hülsenbeck, Beate Köberle, Anamaria Brozović, Maja Osmak, Željka Fiket, Bernd Kaina, Gerhard Fritz,

Although stress-activated protein kinases/c-Jun N-terminal kinases (SAPK/JNK) are rapidly activated by genotoxins, the role of DNA damage in this response is not well defined. Here we show that the SEK1/MKK4-mediated dual phosphorylation of SAPK/JNK (Thr-183/Tyr-185) correlates with the level of cisplatin-DNA adducts at late times (16-24 h) after drug treatment in both human and mouse cells. Transfection of platinated plasmid DNA also caused SAPK/JNK activation. A defect in transcription-coupled nucleotide ...

Tópico(s): Effects of Radiation Exposure

2011 - Elsevier BV | Journal of Biological Chemistry

Artigo

Hans Lecher, F. W. Holschneider, Karl Köberle, Walter Speer, Paul Stöcklin,

... Search for more papers by this authorFritz Holschneider, Fritz Holschneider Chem. Laborat. d. Universität Freiburg i. B.Search for more papers by this authorKarl Köberle, Karl Köberle Chem. Laborat. d. Universität Freiburg i. ... Search for more papers by this authorFritz Holschneider, Fritz Holschneider Chem. Laborat. d. Universität Freiburg i. B.Search for more papers by this authorKarl Köberle, Karl Köberle Chem. Laborat. d. Universität Freiburg i. ...

Tópico(s): Axial and Atropisomeric Chirality Synthesis

1925 - Wiley | Berichte der Deutschen Chemischen Gesellschaft. Abteilung B, Abhandlungen

Artigo Acesso aberto Revisado por pares

Thomas M. Rünger, Steffen Emmert, Dirk Schadendorf, Caroline Diem, Bernd Epe, Doris Hellfritsch,

... group A protein in testicular germ cell tumors (Koberle et al., 1999Koberle B. Masters J.R. Hartley ...

Tópico(s): Cancer Genomics and Diagnostics

2000 - Elsevier BV | Journal of Investigative Dermatology

Artigo Acesso aberto Revisado por pares

Deborah M. Anderson, Nancy Ciletti, Hanni Lee-Lewis, Derek Elli, Joshua Segal, Kristin L. DeBord, Katie A. Overheim, Maria Tretiakova, Robert R. Brubaker, Olaf Schneewind,

... 5131Crossref PubMed Scopus (61) Google Scholar, 34Adkins I Koberle M Grobner S Bohn E Autenrieth I Borgmann ...

Tópico(s): Zoonotic diseases and public health

2009 - Elsevier BV | American Journal Of Pathology

Revisão Acesso aberto Revisado por pares

Praveen Sethupathy,

... 5: 1428-1432PubMed Google Scholar), cirrhosis (13Waidmann O. Koberle V. Brunner F. Zeuzem S. Piiper A. Kronenberger ...

Tópico(s): RNA modifications and cancer

2013 - Elsevier BV | Journal of Lipid Research

Artigo Revisado por pares

Eva C. Wunderlich,

... today offer religious interpretation is shown by Adolf Köberle’s Bach, Beethoven, Bruckner (Tübingen, 1947). Also the ... Profundis, p. 373.Jochen Klepper, Gedichte, ed. by Fritz Wenzel (Berlin, 1947), p. 21.Published in a ...

Tópico(s): Literature and Cultural Memory

1949 - Routledge | The Germanic Review Literature Culture Theory