Muneyoshi Kimura, Yuki Asano‐Mori, Takashi Sakoh, Masahiro Abe, Keigo Ueno, Yasutaka Hoshino, Shigeki Nakamura, Takashi Umeyama, Satoshi Yamagoe, Yoshitsugu Miyazaki, Masaru Baba, Chikako Okada, Sho Ogura, Takashi Mitsuki, Kyosuke Yamaguchi, Mitsuhiro Yuasa, Daisuke Kaji, Kosei Kageyama, Aya Nishida, Yuki Taya, Kazuya Ishiwata, Shinsuke Takagi, Hisashi Yamamoto, Go Yamamoto, Naoyuki Uchida, Atsushi Wake, Shuichi Taniguchi, Hideki Araoka,
Limited data are available on breakthrough fungemia, defined as fungemia that develops on administration of antifungal agents, in patients with hematological disorders. We reviewed the medical and microbiological records ... adult patients with hematological diseases who had breakthrough fungemia between January 2008 and July 2019 at Toranomon ... Japan. A total of 121 cases of breakthrough fungemia were identified. Of the 121 involved patients, 83, ... The crude 14-day mortality rate of breakthrough fungemia was 36%. Significant independent factors associated with the ...
Tópico(s): Pharmacological Effects of Natural Compounds
2022 - American Society for Microbiology | Antimicrobial Agents and Chemotherapy
Abd Elazeez Shabaan, Lobna Mahmoud Elbaz, Wafaa Elemshaty, Basma Shouman,
... d-glucan level for early diagnosis of invasive fungemia in high-risk infants admitted to a neonatal ... based on blood culture into three groups: no fungemia (41 neonates with proven bacterial sepsis), suspected fungemia (25 neonates with negative blood culture), and definite fungemia group (11 neonates with culture-proven Candida). The ... glucan concentration was significantly lower in the no fungemia group when compared with the definite fungemia group. The best cut-off value of (1, ... D-glucano no soro para diagnóstico precoce de fungemia invasiva em neonatos de alto risco internados em ...
Tópico(s): Infections and bacterial resistance
2017 - Elsevier BV | Jornal de Pediatria
Yi‐Ming Fan, Wenming Huang, Yanping Yang, Wen Li, LI Shun-fan,
... definite clinicopathologic evidence except for the patient with fungemia reported by Gunn et al,5Gunn S.R. ... H. Use of DNA sequencing analysis to confirm fungemia due to Trichosporon dermatis in a pediatric patient. ... Scopus (119) Google Scholar The first case of fungemia caused by T dermatis was observed in a ... H. Use of DNA sequencing analysis to confirm fungemia due to Trichosporon dermatis in a pediatric patient. ... H. Use of DNA sequencing analysis to confirm fungemia due to Trichosporon dermatis in a pediatric patient. ...
Tópico(s): Mycobacterium research and diagnosis
2011 - Elsevier BV | Journal of the American Academy of Dermatology
Yves Cohen, Philippe Karoubi, Christophe Adrie, R. Gauzit, T Marsepoil, Daniel Zarka, Christophe Clec’h,
... easy-to-identify risk factors for C. glabrata fungemia likely to guide and improve initial antifungal therapy. ... known Candida colonization who had blood culture-confirmed fungemia over a 4-yr period.None.A total ... hundred fifty-four patients with blood culture-confirmed fungemia constituted the cohort, of whom 48 had C. glabrata fungemia and 106 had nonglabrata fungemia. Patients' baseline characteristics and in-intensive care unit events potentially related to C. glabrata fungemia were systematically recorded. Compared with patients with nonglabrata ...
Tópico(s): Pneumonia and Respiratory Infections
2010 - Lippincott Williams & Wilkins | Critical Care Medicine
Hee Kyoung Choi, Su Jin Jeong, Han Sung Lee, Bum Sik Chin, Suk Hoon Choi, Sang Hoon Han, Myoung Soo Kim, Chang Oh Kim, Jun Yong Choi, Young Goo Song, June Myung Kim,
... factors associated with C. glabrata and C. krusei fungemia with Candida albicans fungemia and examined the clinical manifestations and prognostic factors ... outcomes associated with C. glabrata and C. krusei fungemia at a tertiary-care teaching hospital during a ... 2006.During the study period, there were 497 fungemia episodes. C. glabrata fungemia accounted for 23 episodes and C. krusei fungemia accounted for 8. Complete medical records were available ... study. Compared to 54 episodes of C. albicans fungemia, renal insufficiency and prior fluconazole prophylaxis were associated ...
Tópico(s): Antibiotic Use and Resistance
2009 - Korean Association of Internal Medicine | The Korean Journal of Internal Medicine
Alexandria Garavaglia Wilson, Scott T. Micek, David J. Ritchie,
... an alternative option for treatment of C glabrata fungemia.The main objective of this study was to ... fluconazole retrospectively as a treatment for C glabrata fungemia.Data were collected through a database that stores ... of these patients followed. The primary outcomes were fungemia eradication and in-hospital mortality.Of the total 124 cases of C glabrata fungemia identified, 54 patient charts were evaluable. Chart review ... no association was found between fluconazole dose and fungemia eradication in the entire study population, higher doses ...
Tópico(s): Neutropenia and Cancer Infections
2005 - Elsevier BV | Clinical Therapeutics
Nurşen Belet, Nazan Dalg, Selim ncel, Ergin Cift i, Erdal nce, Haluk G riz, Meral Barlas, lker Do ru,
... central venous catheters.2 We report catheter-related fungemia caused by S. cerevisiae in a newborn despite ... abdomen showed no evidence of localized infection. Because fungemia persisted during amphotericin B treatment, the umbilical catheter ... induced diarrhea. Recently several reports of S. cerevisiae fungemia associated with the use of S. boulardii have been published.2–4 In addition, fungemia by S. cerevisiae can occur in patients who ... as our case. Cesaro et al3 reported Saccharomyces fungemia in an 8-month-old infant with acute ...
Tópico(s): Actinomycetales infections and treatment
2005 - Lippincott Williams & Wilkins | The Pediatric Infectious Disease Journal
... investigation to determine the species of yeasts causing fungemia in a university hospital in Saudi Arabia during ... 1991-2000. A total of 189 episodes of fungemia were encountered, of which 121 (64%) occurred during ... and Trichosporon beigelii. The percentage of episodes of fungemia caused by C. albicans ranged from 36.4% ... recent years. The incidence of non-C. albicans fungemia decreased from 63 (33.3%) during the first ... episodes during the second 5 years. Moreover, no fungemia due to C. glabrata and C. krusei were ...
Tópico(s): Enterobacteriaceae and Cronobacter Research
2003 - Wiley | Mycoses
V. Petrocheilou-Paschou, Helen Prifti, Evangelos Kostis, Constantine S. Papadimitriou, Meletios Α. Dimopoulos, S. Stamatelopoulos,
... of infection, with only 12 culture-proven rhodotorula fungemia cases reported prior to 1984 [2Kiehn TE Gorey ... Scholar], and since then another five patients with fungemia have been reported in the English-language literature [ ... Fabbri A Nicoletti P Amphotericin B treatment of fungemia due to unusual pathogens in neutropenic patients: report ... Szabadosova V Brandeburova O Krcmery VJ Rhodotorula spp fungemia in an immunocompromised boy after neurosurgery successfully treated ... lipid complexin an AIDS patient with Rhodotorula rubra fungemia.Clin Infect Dis. 1998; 27: 892-893Crossref PubMed ...
Tópico(s): Plant Pathogens and Fungal Diseases
2001 - Elsevier BV | Clinical Microbiology and Infection
Jalal Abbas, Gerald P. Bodey, Hend Hanna, Masoud Mardani, Essam Girgawy, Dima Abi-Said, Estella Whimbey, Ray Hachem, Issam Raad,
... and is emerging as a frequent cause of fungemia in patients with hematologic malignant neoplasms.To determine ... risk and prognostic factors associated with C krusei fungemia in comparison with Candida albicans fungemia in patients with cancer.Retrospective study of 57 cases of C krusei fungemia occurring at the M. D. Anderson Cancer Center, ... were compared with 57 cases of C albicans fungemia with respect to demographics, underlying cancer, Acute Physiology ... during 1993 through 1996. Patients with C krusei fungemia more often had leukemia than patients with C ...
Tópico(s): Neutropenia and Cancer Infections
2000 - American Medical Association | Archives of Internal Medicine
Lisa-Gaye Robinson, Lucky Jain, Athena P. Kourtis,
... changed again at that time (Day 7 of fungemia). On the tenth day of fungemia the infant's antifungal therapy was changed to ... for 1 week. On the 15th day of fungemia the Abelcet dose was increased to 7.5 ... albicans blood isolate from the tenth day of fungemia was susceptible to amphotericin (MIC 0.25, 58 ... of therapeutic interventions in a VLBW infant with fungemia. abs, abscess.Discussion. Disseminated systemic candidiasis has become ... demonstrated successful treatment of 25 episodes of neonatal fungemia with fluconazole monotherapy.5 In our patient amphotericin ...
Tópico(s): Pneumocystis jirovecii pneumonia detection and treatment
1999 - Lippincott Williams & Wilkins | The Pediatric Infectious Disease Journal
A.T.A.E. Eltahawy, Ragaa M. F. Khalaf,
Case ReportsRhodotorula Rubra Fungemia in an Immunocompromised Patient Ahmed T.A. El-Tahawy and MD, PhD Ragaa M.F. KhalafMD, PhD Ahmed T. ... total and differential white blood cells before the fungemia were within normal limits.Figure 1. Gram-stained ... all of which are known risk factors for fungemia. The digestive tract could have been the source of R. rubra fungemia in this patient, and this may have been ... Marinova et al. reported a case of Rhodotorula fungemia in a 13-year-old boy after neurosurgery. ...
Tópico(s): Neutropenia and Cancer Infections
1999 - King Faisal Specialist Hospital and Research Centre | Annals of Saudi Medicine
Thomas J. Walsh, William G. Merz, James W. Lee, Robert L. Schaufele, Tin Sein, Patricia Whitcomb, M Ruddel, William R. Burns, John R. Wingard, Arthur C. Switchenko, Thomas C. Goodman, Philip A. Pizzo,
... in 31 (74%) of all 42 cases of fungemia and 25 (83%) of the 30 cases of the subset of persistent fungemia. Elevated DA/Cr was detected in 4 (40%) ... empirical amphotericin B. Among 26 assessable cases of fungemia, abnormally elevated DA/Cr values were detected in ... 8%) simultaneously with the first microbiologic report of fungemia. The trends of serial DA/Cr values correlated ... 85%) of 34 patients with assessable cases of fungemia, decreasing in 8 (89%) of 9 patients with clearance of fungemia and increasing in 21 (84%) of 25 patients ...
Tópico(s): Leprosy Research and Treatment
1995 - Elsevier BV | The American Journal of Medicine
F. Meunier–Carpentier, Timothy E. Kiehn, Donald Armstrong,
... Cancer Center (MSKCC). The incidence of Candida tropicalis fungemia increased each year. Seventy-six percent of the patients with C. tropicalis fungemia and 32.5 percent of those with C. albicans fungemia had either leukemia or lymphoma. Seventy-seven percent ... seven percent of the patients with C. albicans fungemia were receiving oral prophylactic nystatin therapy. The source of fungemia was often difficult to determine: in 60 percent ... in 50.9 percent of 57 patients with fungemia who were tested and may be a valid ...
Tópico(s): Neutropenia and Cancer Infections
1981 - Elsevier BV | The American Journal of Medicine
Jeffrey J. Klein, Chatrchai Watanakunakorn,
Eighty-five episodes of hospital-acquired fungemia in 77 adult patients were reviewed. The predominant risk factors associated with fungemia were prior antibiotic therapy (100 per cent), indwelling intravenous ( ... of four clinical courses: (1) spontaneous resolution of fungemia (42.8 per cent), (2) endophthalmitis after apparent spontaneous resolution of fungemia (5.1 per cent), (3) illness of a ... or (4) no antifungal therapy and death from fungemia (20.7 per cent). Endophthalmitis was documented in 14 per cent of the patients with fungemia. The over-all mortality was 56 per cent ...
Tópico(s): Ocular Diseases and Behçet’s Syndrome
1979 - Elsevier BV | The American Journal of Medicine
G. Kovačičová, Marcela Lovaszova, J. Hanzen, A. Roidová, F Mateička, Michal Lesay, V. Krčméry,
... risk factors and mortality in patients with persistent fungemia (PF). Cases of persistent fungemia, defined as positive blood culture for at least ... antifungal therapy were selected. Forty cases of persistent fungemia (lasting more than 3 days) were compared with ... 37.5%) died, 7 of whom due to fungemia. Nineteen cases had one known risk factor (10 ... and one had 4 risk factors for persistent fungemia. Artificial ventilation, C. glabrata etiology, non-Candida spp. ... and prior surgery were significantly associated with persistent fungemia in univariate, whereas only C. glabrata etiology in ...
Tópico(s): Cardiovascular Syncope and Autonomic Disorders
2001 - Taylor & Francis | Journal of Chemotherapy
Mario Fernández-Ruiz, Jesús Guinea, Mireia Puig‐Asensio, Óscar Zaragoza, Benito Almirante, Manuel Cuenca‐Estrella, José María Aguado,
Fungemia due to rare yeasts constitutes an emerging but poorly investigated condition. Data on risk factors, clinical features, therapy, and outcome of episodes of fungemia due to rare (non-Candida, non-Cryptococcus) yeasts ... centrally performed. Fourteen out of 767 episodes of fungemia (1.8%) were due to rare yeasts: Trichosporon ... local laboratories was observed in two isolates. Breakthrough fungemia occurred in two episodes due to M. capitatus ... 1 mg/l to amphotericin B. Patients with fungemia due to rare yeasts were more likely to ...
Tópico(s): Yeasts and Rust Fungi Studies
2016 - Oxford University Press | Medical Mycology
Benito Almirante, Dolors Rodríguez-Pardo, Manuel Cuenca‐Estrella, Manel Almela, F Sánchez, Josefina Ayats, Carles Alonso-Tarrés, Juan L. Rodríguez‐Tudela, Albert Pahissa,
... has emerged as an important yeast species causing fungemia. We describe the incidence and epidemiology of C. parapsilosis fungemia. Data from active population-based surveillance in Barcelona, ... We focused on 78 episodes of C. parapsilosis fungemia, and we compared them with 175 Candida albicans ... Forty-two episodes (51%) were considered catheter-related fungemia, 35 (45%) were considered primary fungemia, and 3 (4%) were considered secondary fungemia. Risk factors for candidemia were vascular catheterization (97%), ...
Tópico(s): Nail Diseases and Treatments
2006 - American Society for Microbiology | Journal of Clinical Microbiology
Alexander T. Kessler, Athena P. Kourtis, Neal P. Simon,
Malassezia furfur fungemia can cause sepsis in low birth weight neonates receiving parenteral lipids through central intravenous catheters. Its presentation has ... without evidence of endocarditis associated with M. furfur fungemia, an association not previously described. Malassezia furfur (also ... in immunocompromised or seriously ill adults. 3M. furfur fungemia causes a spectrum of presenting signs, ranging from ... neonate with peripheral thromboembolism associated with M. furfur fungemia which resolved completely after the central venous catheter ...
Tópico(s): Fungal Infections and Studies
2002 - Lippincott Williams & Wilkins | The Pediatric Infectious Disease Journal
Dimitrios P. Kontoyiannis, Irfan Vaziri, Hend Hanna, Maha Boktour, Jack Thornby, Ray Hachem, Gerald P. Bodey, Issam Raad,
... risk factors for and presentation of Candida tropicalis fungemia, in comparison with those of Candida albicans, have ... characterized. We compared 43 cases of C. tropicalis fungemia with 148 cases of C. albicans fungemia. In univariate analysis, patients with C. tropicalis fungemia were more likely to have leukemia (P = .0006), ... Evaluation (APACHE) II score, frequency of catheter-associated fungemia, or response to antifungals. In multivariate analysis, patients with C. tropicalis fungemia were more likely to have leukemia (P = .02), ...
Tópico(s): Fungal Infections and Studies
2001 - Oxford University Press | Clinical Infectious Diseases
Jong Hee Shin, Dong-Hyeon Shin, Jeong Won Song, Seung Jung Kee, Soon‐Pal Suh, Dong Wook Ryang,
... isolates of Candida parapsilosis during persistent or recurrent fungemia and the effect of central venous catheter (CVC) ... obtained from 17 patients with persistent or recurrent fungemia over periods of up to 5 months. Forty- ... sequentially isolated from each of seven patients whose fungemia resolved following CVC removal had the same karyotype. Two patients with fungemia that cleared without CVC removal each had two ... In six (75%) of the eight patients whose fungemia was recurrent even after CVC removal, the karyotypes ...
Tópico(s): Streptococcal Infections and Treatments
2001 - American Society for Microbiology | Journal of Clinical Microbiology
Pietro Martino, Corrado Girmenia, Alessandra Micozzi, Ruggero Raccah, Giuseppe Gentile, Mario Venditti, Franco Mandelli,
A nine-year retrospective study on fungemia in patients with leukemia was conducted. A total of 79 episodes of fungemia in 77 patients with leukemia were documented. Candida parapsilosis fungemia was associated more frequently with the presence of ... Candida albicans and in 89% of Candida tropicalis fungemia (p < 0.01 and p = 0.02, respectively). ... was 21% (p = 0.000059). In patients with fungemia, related or unrelated to the presence of a ... catheter as predisposing factors in the development of fungemia in patients with leukemia. The prognosis of patients ...
Tópico(s): Complementary and Alternative Medicine Studies
1993 - Elsevier BV | The American Journal of the Medical Sciences
... With better understanding of the predisposing factors for fungemia in critically ill patients, interest now centers on ... therapy, prior to the progression of colonization to fungemia. Recent prospective trials have identified persistence of Candida ... as an essential if not necessary precursor for fungemia. Treatment for patients requiring prolonged intensivecare-unit residence ... the frequency with which such patients progress to fungemia. The efficacy of such treatment is undocumented, and ... With better understanding of the predisposing factors for fungemia in critically ill patients, interest now centers on ...
Tópico(s): Antibiotic Use and Resistance
1996 - Elsevier BV | The American Journal of Surgery
Teresa K. F. Wang, Kwok‐Yung Yuen, Samson S. Y. Wong,
... report the first case of asymptomatic P. marneffei fungemia in an HIV-infected patient. A 47-year- ... he remained asymptomatic despite the episode of documented fungemia. The isolation of P. marneffei should be considered as genuine fungemia as the fungus has never been known to cause contamination of blood cultures. Secondly, the fungemia appeared to be transient as the fungus was ... This case suggests that transient asymptomatic P. marneffei fungemia is also possible. From a previously reported serological ...
Tópico(s): Plant-Microbe Interactions and Immunity
2007 - Elsevier BV | International Journal of Infectious Diseases
Ting-Yu Tseng, Tsung‐Chia Chen, Cheng‐Mao Ho, Po‐Chang Lin, Chia-Huei Chou, Chia-Ta Tsai, Jen-Hsien Wang, Francesco Bianchi-Demicheli, Mao‐Wang Ho,
... is rarely isolated from clinical specimen. C. guilliermondii fungemia is seldom reported in the literature. The aims ... susceptibility, and outcomes of patients with C. guilliermondii fungemia. From 2003 to 2015, we retrospectively analyzed the ... and laboratory data of patients with C. guilliermondii fungemia in a tertiary hospital in mid-Taiwan. We ... study, we identified 36 patients with C. guilliermondii fungemia. The median age of patients was 50.5 ... 56%) were male. The incidence of C. guilliermondii fungemia was 0.05 per 1000 admissions. Malignancy was ...
Tópico(s): Antimicrobial Resistance in Staphylococcus
2017 - Elsevier BV | Journal of Microbiology Immunology and Infection
Jiwon Jung, Young Sook Moon, Jung A. Yoo, Ji‐Hun Lim, Joseph Jeong, Jae‐Bum Jun,
Candida pelliculosa is a rare pathogen of fungemia. There have been a few nosocomial outbreaks of C. pelliculosa fungemia in nurseries and pediatric intensive care units (ICU), hematologic units, and surgical ... outbreak investigation, including case findings of C. pelliculosa fungemia in South Korea.This outbreak investigation conducted in ... unit (ICU) with multiple trauma developed C. pelliculosa fungemia, and 10 patients in the trauma ICU, medical ... and 2 general wards subsequently contracted C. pelliculosa fungemia during the next 24 days (November 16 and ...
Tópico(s): Oral microbiology and periodontitis research
2017 - Elsevier BV | Journal of Microbiology Immunology and Infection
J. Jensen, Patricia Muñóz, Jesús Guinea, Marta Rodríguez‐Créixems, Teresa Peláez, Emilio Bouza,
Fungemia has been historically considered to be a disease caused by a single Candida species; the detection ... traditional microbiological procedures. We describe episodes of mixed fungemia (MF), detected between 1985 and 2006, in a ... been identified. Overall, we documented 747 cases of fungemia. During the first period (1985-1994), we identified 217 episodes of fungemia and no single episode of MF; during the ... of MF were detected among 530 episodes of fungemia (2.8%). Candida albicans was isolated in 13 ...
Tópico(s): Cystic Fibrosis Research Advances
2007 - Oxford University Press | Clinical Infectious Diseases
Siew Fah Yeo, Sharon Huie, André N. Sofair, Sheldon Campbell, Amanda Durante, Brian Wong,
... 30 healthy adults, 100 hospitalized controls without Candida fungemia, and 83 patients from a study of all ... were less frequent in patients with cancer or fungemia caused by the DA nonproducer Candida glabrata than in patients with cancer or fungemia caused by a DA producer, C. albicans , C. ... for 30 (36%), 22 (27%), and 11 (13%) fungemia patients, respectively. Mortality did not differ significantly among ... 3 or more days after the onset of fungemia (18/27 versus 4/24 patients, respectively; P < ... useful both for the initial diagnosis of Candida fungemia and for prognostic purposes for unselected patients with ...
Tópico(s): Fungal Infections and Studies
2006 - American Society for Microbiology | Journal of Clinical Microbiology
N. F. Fiore, James H. Conway, Karen W. West, Martin B. Kleiman,
... old.12 Only 9 cases were associated with fungemia, with 4 patients surviving.3, 5, 6, 8, ... 17 We describe 3 children with S. cerevisiae fungemia, of whom 2 survived, review previously reported fungemia cases and summarize recommendations for management. Case reports. ... only with the aid of a guide wire. Fungemia persisted for the entire course of amphotericin B. ... patients; 19 of the samples were from sputum. Fungemia was not reported. In instances in which S. ... and amphotericin B and/or ketoconazole.11, 12 Fungemia with S. cerevisiae was reported in 9 patients, ...
Tópico(s): Milk Quality and Mastitis in Dairy Cows
1998 - Lippincott Williams & Wilkins | The Pediatric Infectious Disease Journal
Brita Bruun, Henrik Westh, Jørgen Stenderup,
OBJECTIVE: To present data on episodes of fungemia in a Danish tertiary-care university hospital admitting all types of patients and to compare the data with previous findings from the same hospital. METHODS: Retrospective identification of episodes of fungemia from 1989 to 1994 and collection of data ... Laboratory at Statens Seruminstitut. RESULTS: The incidence of fungemia increased gradually from 19 episodes in 1989 to ... same hospital showed 20 to 25 episodes of fungemia per year between 1984 and 1988. Candida albicans ...
Tópico(s): Respiratory and Cough-Related Research
1995 - Elsevier BV | Clinical Microbiology and Infection