Gibran Benítez-García, Lidia Prudente-Tixteco, Luis Carlos Castro-Madrid, Rocío Toscano-Medina, Jesús Olivares-Mercado, Gabriel Sánchez-Pérez, Luis Javier García Villalba,
Hand gesture recognition (HGR) takes a central role in human–computer interaction, covering a wide range of applications in the automotive sector, consumer electronics, home automation, and others. In recent years, accurate and efficient deep learning models have been proposed for real-time applications. However, the most accurate approaches tend to employ multiple modalities derived from RGB input frames, such as optical flow. This practice limits real-time performance due to intense extra computational ...
Tópico(s): Hearing Impairment and Communication
2021 - Multidisciplinary Digital Publishing Institute | Sensors
Leonel Rosas-Arias, Gibran Benítez-García, José Portillo-Portillo, Jesús Olivares-Mercado, Gabriel Sánchez-Pérez, Keiji Yanai,
Recent works of real-time semantic segmentation, remove or make use of light decoders from dense deep neural networks to achieve fast inference speed. This strategy helps to achieve real-time performance; however, the accuracy is significantly compromised in comparison to non-real-time methods. In this paper, we introduce two key modules aimed to design a high-performance decoder for real-time semantic segmentation, which also reduces the accuracy gap between real-time and non-real-time networks. ...
Tópico(s): Anomaly Detection Techniques and Applications
2021 - Institute of Electrical and Electronics Engineers | IEEE Transactions on Intelligent Transportation Systems
Demetrio Sierra‐Mercado, Gabriel Lázaro‐Muñoz,
This article refers to:Beyond Consent: Building Trusting Relationships With Diverse Populations in Precision Medicine Research
Tópico(s): Healthcare cost, quality, practices
2018 - Taylor & Francis | The American Journal of Bioethics
Peter Zuk, Laura Torgerson, Demetrio Sierra‐Mercado, Gabriel Lázaro‐Muñoz,
This article reviews neuroethics issues that arise with the development, translation, and use of technologies for neuromodulation. Three electronic databases (PubMed, Embase, and PhilPapers) were searched for relevant articles published between 1/1/16–6/26/18. We focus on pressing ethical issues related to the use of deep brain stimulation (DBS), adaptive DBS (aDBS), transcranial magnetic stimulation (TMS), transcranial direct current stimulation (tDCS), and associated technologies. The neuroethics issues ...
Tópico(s): Psychosomatic Disorders and Their Treatments
2018 - Elsevier BV | Current Opinion in Biomedical Engineering
Elmer Zapata-Mercado, Gabriel Biener, Daniel M. McKenzie, William C. Wimley, Elena B. Pasquale, Valericǎ Raicu, Kalina Hristova,
The receptor tyrosine kinase (RTK) EphA2 is expressed in epithelial and endothelial cells and controls the assembly of cell-cell junctions. EphA2 has also been implicated in many diseases, including cancer. Unlike most RTKs, which signal predominantly as dimers, EphA2 readily forms high-order oligomers upon ligand binding. Here, we investigated if a correlation exists between EphA2 signaling properties and the size of the EphA2 oligomers induced by multiple ligands, including the widely used ephrinA1- ...
Tópico(s): Hippo pathway signaling and YAP/TAZ
2022 - Elsevier BV | Journal of Biological Chemistry
Gibran Benítez-García, Jesús Olivares-Mercado, Gabriel Sánchez-Pérez, Mariko Nakano-Miyatake, Héctor Pérez-Meana,
Several algorithms have been proposed for constrained face recognition applications. Among them the eigenphases algorithm and some variations of it using sub-block processing, appears to be desirable alternatives because they achieves high face recognition rate, under controlled conditions. However, their performance degrades when the face images under analysis present variations in the illumination conditions as well as partial occlusions. To overcome these problems, this paper derives the optimal ...
Tópico(s): Image Processing Techniques and Applications
2012 - Elsevier BV | Knowledge-Based Systems
Leonel Rosas-Arias, José Portillo-Portillo, Aldo Hernandez-Suarez, Jesús Olivares-Mercado, Gabriel Sanchez-Perez, Karina Toscano, Héctor Pérez-Meana, Ana Lucila Sandoval Orozco, Luis Javier García Villalba,
The counting of vehicles plays an important role in measuring the behavior patterns of traffic flow in cities, as streets and avenues can get crowded easily. To address this problem, some Intelligent Transport Systems (ITSs) have been implemented in order to count vehicles with already established video surveillance infrastructure. With this in mind, in this paper, we present an on-line learning methodology for counting vehicles in video sequences based on Incremental Principal Component Analysis ( ...
Tópico(s): Autonomous Vehicle Technology and Safety
2019 - Multidisciplinary Digital Publishing Institute | Sensors
Ingrid Fetter-Pruneda, Helga Geovannini Acuña, Cecilia Santiago, Ana Sofía Ibarrarán-Viniegra, Eduardo Martínez‐Martínez, Marcela Sandoval‐Velasco, Laura Uribe-Figueroa, Patricia Padilla-Cortés, Gabriela Mercado, Gabriel Gutiérrez‐Ospina,
Birth-enucleated rodents display enlarged representations of whiskers (i.e., barrels of the posteromedial subfield) in the primary somatosensory cortex. Although the historical view maintains that barrel expansion is due to incremental increases in neuronal activity along the trigeminal pathway during postnatal development, recent evidence obtained in experimental models of intramodal plasticity challenges this view. Here, we re-evaluate the role of experience-dependent neuronal activity on barrel ...
Tópico(s): Sleep and Wakefulness Research
2013 - Public Library of Science | PLoS ONE
Lifeng Yang, Tyler J. Moss, Lingegowda S. Mangala, Juan C. Marini, Hongyun Zhao, Stephen Wahlig, Guillermo N. Armaiz-Peña, Dahai Jiang, Abhinav Achreja, Julia Win, R Roopaimoole, Cristian Rodriguez‐Aguayo, Imelda Mercado‐Uribe, Gabriel López-Berestein, Jinsong Liu, Takashi Tsukamoto, Anil K. Sood, Prahlad T. Ram, Deepak Nagrath,
Abstract Glutamine can play a critical role in cellular growth in multiple cancers. Glutamine‐addicted cancer cells are dependent on glutamine for viability, and their metabolism is reprogrammed for glutamine utilization through the tricarboxylic acid ( TCA ) cycle. Here, we have uncovered a missing link between cancer invasiveness and glutamine dependence. Using isotope tracer and bioenergetic analysis, we found that low‐invasive ovarian cancer ( OVCA ) cells are glutamine independent, whereas high‐invasive ...
Tópico(s): Immune cells in cancer
2014 - Springer Nature | Molecular Systems Biology
J.M. Hsieh, Gabriel Mercado Besserer, M. Gregor Madej, Ha‐Quyen Bui, Seunghyug Kwon, Jeff Abramson,
Low expression and instability during isolation are major obstacles preventing adequate structure-function characterization of membrane proteins (MPs). To increase the likelihood of generating large quantities of protein, C-terminally fused green fluorescent protein (GFP) is commonly used as a reporter for monitoring expression and evaluating purification. This technique has mainly been restricted to MPs with intracellular C-termini (C(in)) due to GFP's inability to fluoresce in the Escherichia coli ...
Tópico(s): Glycosylation and Glycoproteins Research
2010 - Wiley | Protein Science
James E. Wappes, Julieta Ledezma Arias, Eugenio H. Nearns,
The 144 Coleoptera holotypes in the Museo de Historia Natural, Noel Kempff Mercado, Santa Cruz, Bolivia are listed alphabetically within their respective family. Full literature citations for the original descriptions of listed holotypes are included in the Literature Cited section.
Tópico(s): Coleoptera Taxonomy and Distribution
2009 - Center for Systematic Entomology | Insecta mundi
Vincent Chaptal, Michela Ottolia, Gabriel mercado‐besserer, Debora A. Nicoll, Kenneth D. Philipson, Jeff Abramson,
Tópico(s): Ion Transport and Channel Regulation
2009 - Elsevier BV | Journal of Biological Chemistry
Salem Faham, Akira Watanabe, Gabriel Mercado Besserer, Duilio Cascio, Alexandre Specht, Bruce A. Hirayama, Ernest M. Wright, Jeff Abramson,
Membrane transporters that use energy stored in sodium gradients to drive nutrients into cells constitute a major class of proteins. We report the crystal structure of a member of the solute sodium symporters (SSS), the Vibrio parahaemolyticus sodium/galactose symporter (vSGLT). The ∼3.0 angstrom structure contains 14 transmembrane (TM) helices in an inward-facing conformation with a core structure of inverted repeats of 5 TM helices (TM2 to TM6 and TM7 to TM11). Galactose is bound in the center of the ...
Tópico(s): Pancreatic function and diabetes
2008 - American Association for the Advancement of Science | Science
Gabriel Mercado Besserer, Michela Ottolia, Debora A. Nicoll, Vincent Chaptal, Duilio Cascio, Kenneth D. Philipson, Jeff Abramson,
The Na(+)-Ca(2+) exchanger plays a central role in cardiac contractility by maintaining Ca(2+) homeostasis. Two Ca(2+)-binding domains, CBD1 and CBD2, located in a large intracellular loop, regulate activity of the exchanger. Ca(2+) binding to these regulatory domains activates the transport of Ca(2+) across the plasma membrane. Previously, we solved the structure of CBD1, revealing four Ca(2+) ions arranged in a tight planar cluster. Here, we present structures of CBD2 in the Ca(2+)-bound (1.7-A ...
Tópico(s): Aluminum toxicity and tolerance in plants and animals
2007 - National Academy of Sciences | Proceedings of the National Academy of Sciences
Gabriel Mercado-Vásquez, Denis Boyer, Satya N. Majumdar,
Abstract During a random search, resetting the searcher’s position from time to time to the starting point often reduces the mean completion time of the process. Although many different resetting models have been studied over the past ten years, only a few can be physically implemented. Here we study theoretically a protocol that can be realised experimentally and which exhibits unusual optimization properties. A Brownian particle is subject to an arbitrary confining potential v ( x ) that is switched ...
Tópico(s): Animal Behavior and Reproduction
2022 - Institute of Physics | Journal of Statistical Mechanics Theory and Experiment
Gabriel Mercado-Vásquez, Denis Boyer,
The effects of Poissonian resetting at a constant rate $r$ on the reaction time between a Brownian particle and a stochastically gated target are studied. The target switches between a reactive state and a non-reactive one. We calculate the mean time at which the particle subject to resetting hits the target for the first time, while the latter is in the reactive state. The search time is minimum at a resetting rate that depends on the target transition rates. When the target relaxation rate is much ...
Tópico(s): Mathematical and Theoretical Epidemiology and Ecology Models
2021 - Institute of Physics | Journal of Physics A Mathematical and Theoretical
Gabriel Mercado-Vásquez, Denis Boyer, Satya N. Majumdar, Grégory Schehr,
Abstract We study the non-equilibrium steady states (NESS) and first passage properties of a Brownian particle with position X subject to an external confining potential of the form V ( X ) = μ | X |, and that is switched on and off stochastically. Applying the potential intermittently generates a physically realistic diffusion process with stochastic resetting toward the origin, a topic which has recently attracted a considerable interest in a variety of theoretical contexts but has remained challenging to ...
Tópico(s): Mathematical and Theoretical Epidemiology and Ecology Models
2020 - Institute of Physics | Journal of Statistical Mechanics Theory and Experiment
Lumariz Hernandez Rosario, Juan O. Rodríguez Padilla, Desiree Ramos Martínez, Alejandra Morales Grajales, Joel A. Mercado Reyes, Gabriel J. Veintidós Feliu, Benjamin W. van Ee, Dimuth Siritunga,
The Solanaceae family is one of the largest and well-distributed plant families in the world. It contains species of agricultural and economical importance, such as Solanum tuberosum , Solanum melongena , Solanum lycopersicum , Nicotiana tabacum , and Capsicum annuum . In Puerto Rico, there are ≈46 species of Solanaceae of which six are endemic: Brunfelsia densifolia, Brunfelsia lactea, Brunfelsia portoricensis, Goetzea elegans, Solanum ensifolium , and Solanum woodburyi. Our objective was to use DNA barcoding ...
Tópico(s): Plant and Fungal Species Descriptions
2019 - American Society for Horticultural Science | Journal of the American Society for Horticultural Science
Elizabeth Donohue, Sina Khorsand, Gabriel Mercado, Kristen M. Varney, Paul T. Wilder, Wenbo Yu, Alexander D. MacKerell, Patrick Alexander, Que N. Van, Ben Moree, Andrew G. Stephen, David J. Weber, Joshua Salafsky, Frank McCormick,
Significance KRas is the most frequently mutated oncogene in human cancer, and its critical role in tumorigenesis is well established. Historical challenges in targeting KRas have led to its characterization as an “undruggable” target, but recent advances in drug discovery approaches have revealed promising avenues toward the development of small molecule Ras inhibitors. This study describes the successful implementation of second harmonic generation (SHG) as a screening platform to identify a conformational ...
Tópico(s): Spectroscopy and Quantum Chemical Studies
2019 - National Academy of Sciences | Proceedings of the National Academy of Sciences
Gabriel Mercado-Vásquez, Denis Boyer,
In noisy environments such as the cell, many processes involve target sites that are often hidden or inactive, and thus not always available for reaction with diffusing entities. To understand reaction kinetics in these situations, we study the first hitting time statistics of a one-dimensional Brownian particle searching for a target site that switches stochastically between visible and hidden phases. At high crypticity, an unexpected rate limited power-law regime emerges for the first hitting ...
Tópico(s): Stochastic processes and statistical mechanics
2019 - American Physical Society | Physical Review Letters
Noreen F. Rizvi, John A. Howe, Ali Nahvi, Daniel J. Klein, Thierry Fischmann, Hai‐Young Kim, Mark A. McCoy, Scott S. Walker, Alan Hruza, Matthew P. Richards, Chad Chamberlin, P Saradjian, Margaret T. Butko, Gabriel Mercado, Julja Burchard, Corey Strickland, Peter J. Dandliker, G. Smith, Elliott Nickbarg,
Recent advances in understanding the relevance of noncoding RNA (ncRNA) to disease have increased interest in drugging ncRNA with small molecules. The recent discovery of ribocil, a structurally distinct synthetic mimic of the natural ligand of the flavin mononucleotide (FMN) riboswitch, has revealed the potential chemical diversity of small molecules that target ncRNA. Affinity-selection mass spectrometry (AS-MS) is theoretically applicable to high-throughput screening (HTS) of small molecules binding ...
Tópico(s): RNA modifications and cancer
2018 - American Chemical Society | ACS Chemical Biology
Lifeng Yang, Abhinav Achreja, Tsz-Lun Yeung, Lingegowda S. Mangala, Dahai Jiang, Cecil Han, Joelle Baddour, Juan C. Marini, Joseph Ni, Ryuichi Nakahara, Stephen Wahlig, Lisa Chiba, Sun Hye Kim, Joshua Morse, Sunila Pradeep, Archana S. Nagaraja, Monika Haemmerle, Noh Kyunghee, Mathew Derichsweiler, Thomas Plackemeier, Imelda Mercado‐Uribe, Gabriel López-Berestein, Tyler J. Moss, Prahlad T. Ram, Jinsong Liu, Xiongbin Lu, Samuel C. Mok, Anil K. Sood, Deepak Nagrath,
Summary Reactive stromal cells are an integral part of tumor microenvironment (TME) and interact with cancer cells to regulate their growth. Although targeting stromal cells could be a viable therapy to regulate the communication between TME and cancer cells, identification of stromal targets that make cancer cells vulnerable has remained challenging and elusive. Here, we identify a previously unrecognized mechanism whereby metabolism of reactive stromal cells is reprogrammed through an upregulated glutamine ...
Tópico(s): Cancer Cells and Metastasis
2016 - Cell Press | Cell Metabolism
Eugenia J. Olguín, Gloria Sánchez‐Galván, Gabriel Mercado,
Tópico(s): Wastewater Treatment and Nitrogen Removal
2004 - Elsevier BV | Ocean & Coastal Management
Eugenia J. Olguín, Sonia Galicia, Gabriel Mercado, Teresa Pérez,
Tópico(s): Aquaculture Nutrition and Growth
2003 - Springer Science+Business Media | Journal of Applied Phycology
Gloria Sánchez‐Galván, Eugenia J. Olguín, Gabriel Mercado,
Tópico(s): Agriculture Sustainability and Environmental Impact
1999 - Springer Science+Business Media | Biodegradation
Eugenia J. Olguín, Sonia Galicia, Ruth Camacho, Gabriel Mercado, T. J. Pérez,
Tópico(s): Nematode management and characterization studies
1997 - Springer Science+Business Media | Applied Microbiology and Biotechnology
Eugenia J. Olguín, Horst W. Doelel, Gabriel Mercado,
Tópico(s): Biofuel production and bioconversion
1995 - Elsevier BV | Resources Conservation and Recycling
Eugenia J. Olguín, Benjamín Hernández, Alejandro Araus, Ruth Camacho, Rubén González, Ma. Eugenia Ramírez, Sonia Galicia, Gabriel Mercado,
Tópico(s): Wastewater Treatment and Nitrogen Removal
1994 - Springer Science+Business Media | World Journal of Microbiology and Biotechnology
Benjamin L. Van Duuren, B. M. Goldschmidt, Chen Katz, L. Langseth, Gabriel Mercado, Andrew Sivak,
(1968). Alpha-Haloethers: A New Type of Alkylating Carcinogen. Archives of Environmental Health: An International Journal: Vol. 16, No. 4, pp. 472-476.
Tópico(s): Carcinogens and Genotoxicity Assessment
1968 - Heldref Publications | Archives of Environmental Health An International Journal
Miguel Rubio, Germán Muñoz‐Córdova, Mario Garduño-Lugo, Martha Salazar‐Ulloa, Gabriel Mercado-Vidal,
Gyrodactylids (Monogenea) are ectoparasites of fish, some of which negatively affect commercially valuable fishes. Temperature strongly regulates population dynamics of these viviparous flatworms in farmed and wild fish populations, with most gyrodactylid species showing positive temperature-abundance associations. In agreement with epidemiological theory, numerous laboratory studies demonstrate that these parasites cannot persist in confined fish populations without periodic introduction of susceptible ...
Tópico(s): Parasites and Host Interactions
2011 - Elsevier BV | Veterinary Parasitology