Andrew Robson, Richard Bullick, Gabriele Marcotti, Simon Rushworth, Neil Johnston, Gary Duncan, Peter Lansley, Mark Souster, Richard Hobson, Ian Winrow, Michael Evans Defence Editor, Simon Cambers, Philip Howard, David Lister Scotland Correspondent, David Chater, Joanna Bale, James Ducker, J. a. Rutherford, Carl Mortished, Alison Wilcockson, James Hider, Geoff Brown, Lucy Bannerman, Gemma Clarke, Joe Joseph, Ben Webster Transport Correspondent, Pat Gibson, Valerie Elliott Countryside Editor, John Pentney, Donald Hutera, Dominic Walsh, Steve Bird, James Doran Wall Street Correspondent, Debra Craine, Richard Miller, Fiona Woolf, Tim Reid, Mike Turner, Toby Moore, Tom Gatti, David Hands, Adam LeBor, Mark Giles, Norman Hammond Archaeology Correspondent, Catherine Stihler, Edward Gorman, Angela Jameson, Charlie Rapple, Russell Kempson, Daniel McGrory, Dan Subbagh, Raj Kothari, David Lister, Mark Henderson Science Editor, Neil Harman, Linda Woolley, Rick Broadbent, Tom Baldwin, Brian Winterflood, Edward Gorman Motor Racing Correspondent, Gabriel Rozenberg, Bernard Lagan, R. V. Taylor, Neil Harman Tennis Correspondent, Lewis Smith, Matthew Pryor, Matt Dickinson, Matt Hughes, Dr Tanya Byron, Kaveh Solhekol, Marcus Binney Architecture Correspondent, Ian Kelcey, Jeremy Page, Peta Bee, Bronwen Maddox, Patrick Hosking, Dr Susannah Tomkins, Roger Boyes, Lucy Powell, David Hands Rugby Correspondent, Owen Slot Chief Sports Reporter, Tom Dart, Paul Simons, Philip Webster and Bronwen Maddox, Michael Herman, Mike Mulvihill, William Rees-Mogg, Nick Szczepanik, Philip Webster Political Editor, Tosin Sulaiman, Tim Hames, Deborah Mattinson, Professor David Leon, Michele Kirsch, Dominic Maxwell, Alice Fordham, Thomas Catan, Anjana Ahuja, Michael Smith, Caitlin Moran, Alan Lee, Walter Gammie, Josh Ball, Professor Martin McKee, Tony Dawe, Valerie Elliott Consumer Editor and David Sanderson, Denny Cullip, David Sinclair, Catherine Philp, Martin Waller, Danny Baker, Carl Mortished International Business Editor, Sarah Butler, Benedict Nightingale, Alex Horne, Dr Thomas Stuttaford, Stephen Dalton, Nicola Woolcock, Ben Hoyle, Richard Morrison, Bill Edgar, Alyson Rudd, James Christopher, Tony Halpin, Michael Evans, Franklin Sinclair, Alan Lee Racing Correspondent, Alexandra Blair Education Correspondent, Phllip Webster Political Editor, David Robertson, Jamie Forrester, Christopher Irvine, Tricia Holly Davis, Stephen Pollard,
... Genuine recipe for a Bombay mix arts Marianela Nunez The radicals' reward The Samuel Beckett Prize is ... She may be Argentinian, but the bubbly Marianela Nuñez is the Royal Ballet's best English dancer, ...
2006 - Gale Group | TDA
Simone Lipinski, Steffen Pfeuffer, Philipp Arnold, Christian Treitz, Konrad Aden, Henriette Ebsen, Maren Falk‐Paulsen, Nicolas Gisch, Antonella Fazio, J. W. Kuiper, Anne Luzius, Susanne Billmann-Born, Stefan Schreiber, Gabriel Núñez, Hans‐Dietmar Beer, Till Strowig, Mohamed Lamkanfi, Andreas Tholey, Philip Rosenstiel,
... Search for more papers by this author Gabriel Nuñez Gabriel Nuñez Department of Pathology, School of Medicine, University ... Search for more papers by this author Gabriel Nuñez Gabriel Nuñez Department of Pathology, School of Medicine, University of ...
Tópico(s): interferon and immune responses
2019 - Springer Nature | The EMBO Journal
Dominica Roberts, Phil Yates, Arthur Leathley, Transport Correspondent, Tunku Varadarajan, Jon Ashworth, Jason Niss? and Lucy McDonald, Peter Fairley, Nick Nuttall Environment Correspondent, Michael Aylwin, Brian Greer, Fred Redwood, Kevin Ferrie, D. Politi, Adrian Lee, Jane MacQuitty, Simon Barnes, david gregory, Magnus Linklater, John Morgan, Paul Hoggart, jonathan meades, Mark Souster, Richard Hobson, David Rhys Jones, Mike Lawrence, Gavin Lumsden, Philip Howard, Nick Cave, James Bone and Michael Binyon, Diplomatic Editor, Patrick Collinson, Joanna Bale, James Bone, Rachel Campbell-Johnston, Clive Davis, Oliver Holt Football Correspondent, Lynne Truss, Carl Mortished, Toby Heelis, heath brown, Jeremy Whittle, Tony Patrick, Kevin Eason, john diamond, Geoff Brown, John Major, Gillian Harris and Andrew Pierce, Gerald Davies, Clare Stewart, Louise Godfrey, Jennifer Phillips, Lawrence Dallaglio, Martin Fletcher, Carl Evans, Simon Watney, Director, Pat Gibson, Sam Jary, Robert Sheehan, D. R., zanna, Helen Johnstone and Adrian Lee, Dominic Walsh, Ruth Gledhill, Shirley English, Patrick Humphries, John O'leary, Education Editor, Rita Kleppmann, Carol Price, Ruth Gledhill Religion Correspondent, Helen Castell and Paul Ramsbottom, Alexander Frean and Dominic Kennedy, Candida Crewe, Stephen Farrell, Robin Young, Peter Millar, Rodney Milnes, richard burns, Peter Proudlove, Richard Dawood, Marianne Curphey and Gavin Lumsden, T. P., Humphry Wakefield, Massive Attack, Sue Corbett, Sorrel Downer, Frances Bissell, Mike Bradley, David Hands, P. B., David Long and Les Evans, Michael Cable, Helen Rumbelow, Adrian Lee and Helen Johnstone, Peter Barnard, Anthea Lawson, Victoria Fletcher, Susan Emmett, Jasper Gerard, Russell Kempson, Lizanne Rose, Michael Freedland, Mary Gold, Stephen Anderton, Sarah Johnson, Lisa Grainger, Michael Theodoulou, Sydney Friskin, Stuart Sanders, Frank Leboeuf, John Hopkins, Judith Wilson, L. G., alan jackson, John Hopkins Golf Correspondent, Richard Miles, Banking Correspondent, Ruth Livingstone, Andrew Purkis, Sara Williams, John Whitley, Marcus Binney, Raymond Keene, Vaughan Freeman, David Robinson, Oliver Impey, John Russell Taylor, David Graham, P. W., Lucy Pinney, James Allcock, Martin Fletcher and Philip Webster, Kate Stronach, Sean Hignett, Min Cooper, Nigel Hawkes, Caroline Merrell, Robin Neillands, Heather Kirby, Cathy Harris, Jo Carlowe, Michael Arditti, Howard G. Woodall, Richard Owen, Oliver Holt, David Powell, Athletics Correspondent, E. A. J. Parry, Erica Wagner, Cris Whetton, Michael J. Forbes, D. J. Lane, Mary Ann Percy, Elizabeth Anson, Neil Fullbrook, Stephanie Billen, David Hands Rugby Correspondent, John Haldane, BN, Nick Szczepanik, david adams, Dominic Kennedy, Jane Macquitty, Giles Whittell, Alan Copps, Jason Nisse, Christopher Walker, Jane Shilling, Carol Midgley and Guy Walters, Jason Nissé, Philip Delves Broughton, Deborah King, Kevin McCarra, Richard Evans Racing Correspondent, Mark Hodkinson, Tim Wapshott, John Hopewell, Russell Jenkins, janine di giovanni, Jane Owen, C. S., Helen Pridham, Brian Hunt, Ian Brodie, Brian Glanville, Philip Webster, David Bowker, Graham Searjeant, Simon Jenkins, Tony O'Brien, Michael Fabricant, Chris Ayres, Danny Baker, Lottie Moggach, Mary London, Benedict Nightingale, Antoinette Hart, Marianne Curphey, Damian Thompson, Jill Crawshaw, Stephen Farrell and Kathryn Knight, David Powell, Joe Warwick, Tom Chesshyre, Robin Lodge, David Maddock, Michael Evans, Charlie Porter, Robert Whymant, Horace Mitchell, N. F. Crabb, Christopher Irvine, Jacques Santer, Marianne Curphey Personal Finance Deputy Editor,
... Picture Gallery Tower Great Night in: Director Victor Nunez Short cuts Clive King sees youth crime on ...
1998 - Gale Group | TDA
Mizuho Hasegawa, Yukari Fujimoto, Peter C. Lucas, Hiroyasu Nakano, Koichi Fukase, Gabriel Núñez, Naohiro Inohara,
... Search for more papers by this author Gabriel Núñez Gabriel Núñez Department of Pathology, The University of Michigan ... Search for more papers by this author Gabriel Núñez Gabriel Núñez Department of Pathology, The University of Michigan Medical ...
Tópico(s): Amoebic Infections and Treatments
2007 - Springer Nature | The EMBO Journal
Andrew Robson, David Adams, DJM, Alan Hamilton and Steve Bird, Phlllp Webster, Zahid Hussain, Tanya Byron, Adam Sherwin Media Reporter, Frances Gibb Legal Editor, Gary Duncan, Peter Lansley, Hamish Hardie, Stewart Tendler and Sean O'Neill, Ivo Tennant, Philip Howard, Lucia Van der Post, David Chater, James Bone, James Ducker, Roy Turner, Nic Hopkins, Clive Davis, Richard Irving, Catherine Riley Property Editor, Rajeev Syal and Tom Hennigan, Daniel McGrory and Adam Luck, James Hider, Geoff Brown, David Sharrock, Pat Gibson, Valerie Elliott, James Doran Wall Street Correspondent, Debra Craine, Jill Dupleix, Andrew V. Cooper, Tim Slinger, Ruth Gledhill Religion Correspondent, Dan Sabbagh, Jenny MacArthur, Phil Gordon, Olive Kay, David Hands, Tom Andrews, Stewart Tendler, Sean O'Neill and Daniel McGrory, Tony Combes, Daniel Murdoch, Gary Duncan Economics Editor, Amber Cowan, Robin Wade, Mark Henderson Science Correspondent, Pete Paphides, Simon de Bruxelles, John Hopkins Golf Correspondent, Rob Wright, Anselm Eldergill, David Powell Athletics Correspondent, Marcus Binney, Raymond Keene, Alexandra Frean Social Affairs correspondent, Esmond Birnie, Christine Buckley Industrial Editor, Sean O'Neill, Richard Lloyd Parry Asia Editor, Nigel Hawkes, Jeremy Page, Rick Jones, David Hoursden, Richard Owen, Christopher Martin-Jenkins Chief Cricket Correspondent, Mick Hume, Roger Boyes, Gabriel Rozenberg Economics Reporter, Dalya Alberge, Issandr El Amrani and Stephen Farrell, Tom Dart, Julian Muscat, Paul Simons, Mike Mulvihill, Nick Szczepanik, Mary Ann Sieghart, Jonathan Clayton, Jane Shilling, Bill Wright, Craig Lord, Ian Johns, David Sharrock and Tim Reid, Russell Jenkins, Terry Maher Chairman, Michael Austin, Alan Lee, Neil Fisher, Michael Evans Defence Editor and David Sharrock, Peter Riddell, Ben MacIntyre, Pete Taylor, Peter Fullerton, Rajeev Syal, Lucia van der Post, Jack Malvern Arts Reporter, Jacqui Goddard, David Sinclair, Mark Henderson, Catherine Philp, Martin Waller, Sean O'Neill and Daniel McGrory, Carl Mortished International Business Editor, Ashling O'Connor, Benedict Nightingale, Stephen Dalton, Ben Hoyle, Tim Luckhurst, Leo Lewis, Bill Edgar, David Parsley, Alexandra Blair Education Correspondent, Peter Robinson, Christipher Irvine, Sam Lister Health Correspondent, Patience Wheatcroft, Lisa Verrico, Elizabeth Judge Telecoms Correspondent, Jonathan Hulme,
... into the Hat Beckham hits out at schedule Nuñez goes home Going, Going, Gone Portsmouth boost McCann ...
2005 - Gale Group | TDA
Peter Šťastný, Edward J. Ball, Pamela Jan Dry, Gabriel Núñez,
... USA.Search for more papers by this authorGabriel Nunez, Gabriel Nunez Department of Internal Medicine, The University of ... USA.Search for more papers by this authorGabriel Nunez, Gabriel Nunez Department of Internal Medicine, The University of Texas ...
Tópico(s): Asthma and respiratory diseases
1983 - Wiley | Immunological Reviews
Nina Fukunaga-Johnson, James J. Rayn, Max S. Wicha, Gabriel Nuñez, Michael F. Clarke,
... author on: Oxford Academic PubMed Google Scholar Gabriel Nuñez, Gabriel Nuñez 2Pathology, University of Michigan Medical CenterAnn Arbor, Michigan ...
Tópico(s): PARP inhibition in cancer therapy
1995 - Oxford University Press | Carcinogenesis
Alexander Gottschalk, Carol L. McShan, Ramón Merino, Gabriel Núñez, J Quintáns,
... author on: Oxford Academic PubMed Google Scholar Gabriel Nuñez, Gabriel Nuñez 1Department of Pathology, The University of Michigan Medical ...
Tópico(s): Immunotherapy and Immune Responses
1994 - Oxford University Press | International Immunology
Ilio Vitale, Federico Pietrocola, Emma Guilbaud, Stuart A. Aaronson, John Abrams, Dieter Adam, Massimiliano Agostini, Patrizia Agostinis, Emad S. Alnemri, Lucia Altucci, Ivano Amelio, David W. Andrews, Rami I. Aqeilan, Eli Arama, Eric H. Baehrecke, Siddharth Balachandran, Daniele Bano, Nickolai A. Barlev, Jiří Bártek, Nicolás G. Bazán, Christoph Becker, Francesca Bernassola, Mathieu J.M. Bertrand, Marco E. Bianchi, Mikhail V. Blagosklonny, J. Magarian Blander, Giovanni Blandino, Klas Blomgren, Christoph Borner, Carl D. Bortner, Pierluigi Bove, Patricia Boya, Catherine Brenner, Petr Brož, Thomas Brunner, Rune Busk Damgaard, George A. Calin, Michelangelo Campanella, Eleonora Candi, Michele Carbone, Didac Carmona‐Gutiérrez, Francesco Cecconi, Francis Ka-Ming Chan, Guoqiang Chen, Quan Chen, Youhai H. Chen, Emily H. Cheng, Jerry E. Chipuk, John A. Cidlowski, Aaron Ciechanover, Gennaro Ciliberto, Marcus Conrad, Juan R. Cubillos‐Ruiz, Peter E. Czabotar, Vincenzo D’Angiolella, Mads Daugaard, Ted M. Dawson, Valina L. Dawson, Ruggero De Maria, Bart De Strooper, Klaus‐Michael Debatin, Ralph J. DeBerardinis, Alexei Degterev, Giannino Del Sal, Mohanish Deshmukh, Francesco Di Virgilio, Marc Diederich, Scott J. Dixon, Brian David Dynlacht, Wafik S. El‐Deiry, John W. Elrod, Kurt Engeland, Gian María Fimia, Claudia Galassi, Carlo Ganini, Ana J. García‐Sáez, Abhishek D. Garg, Carmen Garrido, Evripidis Gavathiotis, Motti Gerlic, Sourav Ghosh, Douglas R. Green, Lloyd A. Greene, Hinrich Gronemeyer, Georg Häcker, György Hajnóczky, J. Marie Hardwick, Ygal Haupt, Sudan He, David M. Heery, Michael O. Hengartner, Claudio Hetz, David A. Hildeman, Hidenori Ichijo, Satoshi Inoue, Marja Jäättelä, Ana Janic, Bertrand Joseph, Philipp J. Jost, Thirumala‐Devi Kanneganti, Michael Karin, Hamid Kashkar, Thomas Kaufmann, Gemma L. Kelly, Oliver Kepp, Adi Kimchi, Richard N. Kitsis, Daniel J. Klionsky, Ruth M. Kluck, Dmitri V. Krysko, Dagmar Kulms, Sharad Kumar, Sergio Lavandero, Inna N. Lavrik, John J. Lemasters, Gianmaria Liccardi, Andreas Linkermann, Stuart A. Lipton, Richard A. Lockshin, Carlos López-Otı́n, Tom Luedde, Marion MacFarlane, Frank Madeo, Walter Malorni, Gwenola Manic, Roberto Mantovani, Saverio Marchi, Jean‐Christophe Marine, Séamus J. Martin, Jean‐Claude Martinou, Pier G. Mastroberardino, Jan Paul Medema, Patrick Mehlen, Pascal Meier, Gerry Melino, Sonia Melino, Edward A. Miao, Ute M. Moll, Cristina Muñoz‐Pinedo, Daniel J. Murphy, Maria Victoria Niklison-Chirou, Flavia Novelli, Gabriel Núñez, Andrew Oberst, Dimitry Ofengeim, Joseph T. Opferman, Moshe Oren, Michele Pagano, Theocharis Panaretakis, Manolis Pasparakis, Josef Penninger, Francesca Pentimalli, David M. Pereira, Shazib Pervaiz, Marcus E. Peter, Paolo Pinton, Giovanni Porta, Jochen H.M. Prehn, Hamsa Puthalakath, Gabriel A. Rabinovich, Krishnaraj Rajalingam, Kodi S. Ravichandran, Markus Rehm, Jean‐Ehrland Ricci, Rosario Rizzuto, Nirmal Robinson, Cecília M. P. Rodrigues, Barak Rotblat, Carla V. Rothlin, David C. Rubinsztein, Thomas Rudel, Alessandro Rufini, Kevin M. Ryan, Kristopher A. Sarosiek, Akira Sawa, A. Emre Sayan, Kate Schroder, Luca Scorrano, Federico Sesti, Feng Shao, Yufang Shi, Giuseppe Sica, John Silke, Hans‐Uwe Simon, Antonella Sistigu, Anastasis Stephanou, Brent R. Stockwell, Flavie Strapazzon, Andreas Strasser, Liming Sun, Erwei Sun, Qiang Sun, György Szabadkai, Stephen W. G. Tait, Daolin Tang, Nektarios Tavernarakis, Carol M. Troy, Boris Turk, Nicoletta Urbano, Peter Vandenabeele, Tom Vanden Berghe, Matthew G. Vander Heiden, Jacqueline L. Vanderluit, Alexei Verkhratsky, Andreas Villunger, Silvia von Karstedt, Anne K. Voss, Karen H. Vousden, Domagoj Vucic, Daniela Vuri, Erwin F. Wagner, Henning Walczak, David Wallach, Ruoning Wang, Ying Wang, Achim Weber, Will Wood, Takahiro Yamazaki, Huang‐Tian Yang, Zahra Zakeri, Joanna Zawacka‐Pankau, Lin Zhang, Haibing Zhang, Boris Zhivotovsky, Wenzhao Zhou, Mauro Piacentini, Guido Kroemer, Lorenzo Galluzzi,
Apoptosis is a form of regulated cell death (RCD) that involves proteases of the caspase family. Pharmacological and genetic strategies that experimentally inhibit or delay apoptosis in mammalian systems have elucidated the key contribution of this process not only to (post-)embryonic development and adult tissue homeostasis, but also to the etiology of multiple human disorders. Consistent with this notion, while defects in the molecular machinery for apoptotic cell death impair organismal development ...
Tópico(s): Chemotherapy-induced organ toxicity mitigation
2023 - Springer Nature | Cell Death and Differentiation
Bernard C. Lo, Ilona Kryczek, Jiali Yu, Linda Vatan, Roberta Caruso, Masanori Matsumoto, Yosuke Sato, Michael H. Shaw, Naohiro Inohara, Yuying Xie, Yu L. Lei, Weiping Zou, Gabriel Núñez,
Immune checkpoint inhibitors can stimulate antitumor immunity but can also induce toxicities termed immune-related adverse events (irAEs). Colitis is a common and severe irAE that can lead to treatment discontinuation. Mechanistic understanding of gut irAEs has been hampered because robust colitis is not observed in laboratory mice treated with checkpoint inhibitors. We report here that this limitation can be overcome by using mice harboring the microbiota of wild-caught mice, which develop overt ...
Tópico(s): Cancer Immunotherapy and Biomarkers
2024 - American Association for the Advancement of Science | Science
Clara Eugenia Núñez y Gabriel Tortella (eds.), La maldición divina. Ignorancia y atraso económico en perspectiva histórica, Madrid, Alianza Universidad, 1993, 425 pp. ...
Tópico(s): Medieval and Early Modern Iberia
1995 - Centro de Estudios Constitucionales | Revista de Historia Económica / Journal of Iberian and Latin American Economic History
... Search for more papers by this author Gabriel Núñez Corresponding Author Gabriel Núñez Department of Pathology and Comprehensive Cancer Center, ... Search for more papers by this author Gabriel Núñez Corresponding Author Gabriel Núñez Department of Pathology and Comprehensive Cancer Center, The ... Information Naohiro Inohara1, Liyun Ding1, Shu Chen1 and Gabriel Núñez 1 1Department of Pathology and Comprehensive Cancer Center, ...
Tópico(s): Signaling Pathways in Disease
1997 - Springer Nature | The EMBO Journal
... Search for more papers by this author Gabriel Núñez Corresponding Author Gabriel Núñez Department of Pathology and Comprehensive Cancer Center, ... Search for more papers by this author Gabriel Núñez Corresponding Author Gabriel Núñez Department of Pathology and Comprehensive Cancer Center, The ... Inohara1, Takeyoshi Koseki1, Shu Chen1, Xiaoyu Wu1 and Gabriel Núñez 1 1Department of Pathology and Comprehensive Cancer Center, ...
Tópico(s): Cancer therapeutics and mechanisms
1998 - Springer Nature | The EMBO Journal
Jie Xu, Joseph M. Pickard, Gabriel Núñez,
The NLRP3 inflammasome is dysregulated in autoinflammatory disorders caused by inherited mutations and contributes to the pathogenesis of several chronic inflammatory diseases. In this study, we discovered that disulfiram, a safe US Food and Drug Administration (FDA)-approved drug, specifically inhibits the NLRP3 inflammasome but not the NLRC4 or AIM2 inflammasomes. Disulfiram suppresses caspase-1 activation, ASC speck formation, and pyroptosis induced by several stimuli that activate NLRP3. Mechanistically, ...
Tópico(s): Heme Oxygenase-1 and Carbon Monoxide
2024 - Cell Press | Cell Reports
Galen B. Toews, Vincent Lem, Jonathan C. Weissler, GABRIEL NUNEZ‐OLLERO, Edward J. Ball, Peter Šťastný, Mary F. Lipscomb,
... Texas 75235Search for more papers by this authorGABRIEL NUNEZ-OLLERO, GABRIEL NUNEZ-OLLERO Department of Internal Medicine University of ... Texas 75235Search for more papers by this authorGABRIEL NUNEZ-OLLERO, GABRIEL NUNEZ-OLLERO Department of Internal Medicine University of Texas ...
Tópico(s): Amyloidosis: Diagnosis, Treatment, Outcomes
1986 - Wiley | Annals of the New York Academy of Sciences
Juan Esteban Oyarzún, Marcelo E. Andía, Sergio Uribe, Paula Núñez Pizarro, Gabriel Núñez, Gloria Montenegro, Raquel Bridi,
Nonalcoholic fatty liver disease (NAFLD) is a major cause of morbidity and mortality worldwide. Additional therapies using functional foods and dietary supplements have been investigated and used in clinical practice, showing them to be beneficial. Honeybee pollen from Chile has shown a large concentration of phenolic compounds and high antioxidant activity. In this work, we characterized twenty-eight bee pollen extracts from the central zone of Chile according to botanical origin, phenolic profile, ...
Tópico(s): Antioxidant Activity and Oxidative Stress
2020 - Multidisciplinary Digital Publishing Institute | Molecules
Yuan He, Melody Yue Zeng, Dahai Yang, Benny Motro, Gabriel Núñez,
... to NLRP3 oligomerization and activation remains elusive. Here Gabriel Núñez and colleagues identify a member of the family ...
Tópico(s): Heme Oxygenase-1 and Carbon Monoxide
2016 - Nature Portfolio | Nature
Yuumi Nakamura, Jon Oscherwitz, Kemp B. Cease, Susana M. Chan, Raúl Muñoz-Planillo, Mizuho Hasegawa, Amer E. Villaruz, Gordon Y. C. Cheung, Martin J. McGavin, Jeffrey B. Travers, Michaël Otto, Naohiro Inohara, Gabriel Núñez,
... link between S. aureus and allergic skin disease. Gabriel Nüñez and colleagues show that δ-toxin produced by ...
Tópico(s): Allergic Rhinitis and Sensitization
2013 - Nature Portfolio | Nature
Young-Jae Nam, Kartik Mani, Lily I. Wu, Chang-Fu Peng, John W. Calvert, Roger Foo, Barath Krishnamurthy, Wenfeng Miao, Anthony W. Ashton, David J. Lefer, Richard N. Kitsis,
... procaspase-8 and ubiquitin were obtained from Drs. Gabriel Nunez and Wei Gu, respectively. Mutants derived from pcDNA3. ... We thank Drs. Michael Crow, Wei Gu, and Gabriel Nunez for reagents and Allis Chee for help with ...
Tópico(s): Mitochondrial Function and Pathology
2006 - Elsevier BV | Journal of Biological Chemistry
Chih-Cheng Yang, Ho-Pi Lin, Chang‐Shi Chen, Ya-Ting Yang, Ping‐Hui Tseng, Vivek M. Rangnekar, Ching-Shih Chen,
... forming virus (SFFV) promoter was kindly provided by Gabriel Nunez (University of Michigan, Ann Arbor, MI). LNCaP cells ... under investigation in this laboratory. We thank Dr. Gabriel Nunez (University of Michigan, Ann Arbor, MI) for providing ...
Tópico(s): Cancer-related Molecular Pathways
2003 - Elsevier BV | Journal of Biological Chemistry
Dong-Hyun Kim, Melody Y. Zeng, Gabriel Núñez,
... immune system and our ability to resist infections. Gabriel Núñez at the University of Michigan, USA, and co- ...
Tópico(s): Probiotics and Fermented Foods
2017 - Springer Nature | Experimental & Molecular Medicine
Julio Núñez, Gabriel A. Rabinovich, Justo Sandino, Luis Mainar, Patricia Palau, Enrique Santas, María Pilar Villanueva, Eduardo Núñez, Vicent Bodı́, Francisco J. Chorro, Gema Miñana, Juan Sanchís,
Aims Galectin-3 (Gal-3) and carbohydrate antigen 125 (CA125) have emerged as robust prognostic biomarkers in heart failure. Experimental data have also suggested a potential molecular interaction between CA125 and Gal-3; however, the biological and clinical relevance of this interaction is still uncertain. We sought to evaluate, in patients admitted for acute heart failure, the association between plasma Gal-3 with all-cause mortality and the risk for rehospitalizations among high and low levels of ...
Tópico(s): Signaling Pathways in Disease
2015 - Public Library of Science | PLoS ONE
Omar D Hudson, Martha Nuñez, Gabriel Q. Shaibi,
To examine the influence of ethnicity on liver transaminases among adolescents with type 2 diabetes mellitus (T2DM).A retrospective medical chart review of 57 (30 males and 27 females) newly diagnosed patients with T2DM. Ethnicity was determined by self-report and height, weight, body mass index (BMI) and glycosylated hemoglobin (HbA1c) were obtained using standard clinical procedures. Fasting levels of alanine aminotransaminase (ALT) and aspartate aminotransferase (AST) were collected prior to the initiation ...
Tópico(s): Diabetes Management and Research
2012 - BioMed Central | BMC Pediatrics
Phuong K. Morrow, Gerburg M. Wulf, Joe Ensor, Daniel J. Booser, Julia Ann Moore, P. R. Flores, Yan Xiong, Siyuan Zhang, Ian E. Krop, Eric P. Winer, David W. Kindelberger, Jeanna Coviello, Ayşegül A. Şahin, Rodolfo Núñez, Gabriel N. Hortobágyi, Dihua Yu, Francisco J. Esteva,
Purpose Trastuzumab resistance has been linked to activation of the phosphoinositol 3-kinase (PI3K) pathway. Phosphatase and tensin homolog (PTEN) is a dual phosphatase that counteracts the PI3K function; PTEN loss leads to activation of the Akt cascade and the downstream mammalian target of rapamycin (mTOR). Preclinical studies demonstrated that mTOR inhibition sensitized the response to trastuzumab in mice with HER2 overexpressing and PTEN-deficient breast xenografts. Our trial evaluated the safety ...
Tópico(s): Peptidase Inhibition and Analysis
2011 - Lippincott Williams & Wilkins | Journal of Clinical Oncology
Bilal Alkhaffaf, Aleksandra Metryka, Jane Blazeby, Anne‐Marie Glenny, Ademola Adeyeye, Paulo Costa, Ismael Díez del Val, Suzanne S. Gisbertz, Ali Güner, Simon Law, Hyuk‐Joon Lee, Zongyi Li, Koji Nakada, Daniel Reim, Peter Vorwald, Gian Luca Baiocchi, William Allum, M. Asif Chaudry, Ewen A. Griffiths, Paula Williamson, Iain Bruce, Shasha Li, Yingli He, Zhengfeng Xu, Yingwei Xue, Hailun Liang, Guanghe Li, Enfeng Zhao, PJ Neumann, Linda O’Neill, Emer Guinan, Daniela Zanotti, Giovanni De Manzoni, Eliza Hagens, Mark I. van Berge Henegouwen, P. Lages, Susana Onofre, Rafael Mauricio Restrepo Nuñez, Gabriel Salcedo Cabañas, M Posada Gonzalez, C Marin Campos, Bernard Candas, Birdoğan Baki, Muhammed Selim Bodur, Reyyan Yıldırım, Arif Burak Çekiç, Julia Brown, Kenneth A. Hayes, Iyad N. Daher, R H Gianchandani Moorjani, Ademola Adeyeye, Agodirin Olayide, Alberto M. León-Takahashi, A. Pueyo Rabanal, Andrea Peri, Alex Boddy, Alexander Novotny, Alexandros Charalabopoulos, Ali Alemdar, Amine Souadka, A M Rodrigues Gomes, André Lázaro, A Maciel Da Silva, A do Rosário da Conceição Silva e Santos, Alessandro Guidi, A J Silva Bernardes, Aoife Quinn, Arda Işık, A A Slipek, Bernard Candas, Altinbaş, Bamidele Johnson Alegbeleye, Bang Wool Eom, Barbara Frittoli, B Lonsdale, Benedict D. Rogers, Basil J. Ammori, Beate Rau, Beatrice Molteni, Ben Byrne, B A Villacís-Bermeo, B E Villacís Gallardo, Beyza Köse, C J Sampedro Nogueira, Cláudia Chaves Loureiro, C M Oliveira de Sousa, Chris Collins, CN Ekwunife, Chukwuemeka Osuagwu, C L.-Y Wong, C. Winkler, Daniel Reim, Daniel Willy Kjær, D. James Cooper, Daniel Horner, D Irvine, David J. Bowrey, D. Chuter, Diane L. Elliot, Damon McGhee, Dániel Tóth, Dietmar Öfner, Dimitrios K. Manatakis, D R Silveira Martins, Eric J.T. Belt, Elena Cattaneo, Elgun Samadov, Elif Çolak, Elio Treppiedi, Elisa Guglielmi, Elisabeth Redondo-Villahoz, Enrico Ciferri, E Tiemens-de Graaf, Eugenio Cocozza, E. Pape, E. S. Drozdov, Fiorenza Enrico, Fouzia Rashid, Fabiano Di Marco, F. Gómez De la Rosa, F Mingol Navarro, Fabio Perrotta, Feng-Tse Chan, Flávio Daniel Saavedra Tomasich, Flávio Roberto Takeda, Francis X. Farrell, FunmilolaOlanike Wuraola, G. Rosero, Generoso Bevilacqua, G Baronio, Giorgio Mura, Giovanni De Manzoni, G D'Eugenio, Gloria Ortega‐Pérez, G Tilt, Grant Sutcliffe, Gian Francesco Mureddu, Greeshma Jacob, Giovanni Daneri, H Olufemi Gbenga, Hiroshi Okabe, Ingrid Smith, I Olawale Lateef, I. Garosio, İrem Hatipoglu, Ines Gockel, Ionuț Negoi, Insoon Min, I M M Mesquita, Ismael Díez del Val, Janna Leemhuis, James Gossage, J Weindelmayer, Jakob R. Izbicki, J McKenzie Manson, J Kelly, J H M B Stoot, Jan-Willem Haveman, Jonathan Brown, J Sultan, J Hassall, Johanna van Sandick, Jimmy Saunders, J.K. Clarke, J Heisterkamp, Jayalakshmi .R, J M Couselo Villanueva, Julie Ingmire, J. McEwen, Julián Álvarez, Jane Turner, Juan Peng, Kim Roberts, K G Brandon, Kristina Mitchell, K. C. McCarthy, Khurshid Akhtar, Katja Mikhailovich, Laura Corbelli, Leonardo Medeiros Milhomem, L Solaini, L Fengyuan, Xinchun Li, L Timmermans, Lord Porritt, Lucio Taglietti, Luigi Bonavina, L.F. Pinheiro, Marta Ossorio, Massimo Schiavo, M Marchesiello, Maurilo Leite, M DeMois, M Posada Gonzalez, M T Di Felice, Mark I. van Berge Henegouwen, M D de Sousa, Masato Takahashi, M Forshaw, Mattia Berselli, M.M. Kardum Paro, M A Usta, M.-H Yan, M Pinchin, M. Caprioli, M Rubbini, Mark E. Cowen, M A Herrera Servin, Michael Li, Mitsuru Sasako, Mohammad Shukri Jahit, Morris Muhinga, M A Tareen, M F Ahmad, Muhammed Selim Bodur, Mia Audia Br Kaban, Naheed Farooq, Natalie G. Coburn, Nichola Cooper, Natalie Blencowe, N Loria, Nathalie de Vries, NA Andreollo, Nurhan Köksal, Nicola Zanini, Nicole Kreuser, Nuri Okkabaz, O Damiana, OludolapoO Afuwape, O Kayode Fasiku, O Comensoli, Oyintonbra Koroye, P Capener, Paolo Morgagni, P. Lages, Paul M Wilkerson, Paul Turner, Peter Dutton, Paul D. Hayes, Peter Vorwald, Prashant Singh, Qihong Gan, Rajkumar Kottayasamy Seenivasagam, Ramakrishnan Ayloor Seshadri, R Guevara Castro, Robert Douglas, R. Koshy, Ruken Yıldırım, Richard J.E. Skipworth, Rob Gould, R C Wetherill, Rajib Shaw, Ryan Burley, R Palatucci, R Racalbuto, Rui Casaca, Sjoerd M. Lagarde, Simone Gana, Sara Marietti, Samera Azeem Qureshi, Salvador Morales‐Conde, Sarah Molfino, Savio George Barreto, Serdar Türkyılmaz, S Turan-Trabzon, Suzy Frisch, Simone Castoldi, Silvia Belloni, Sara Flisi, Stacey Galloway, Suzy Maria, Simon Royston, T Boyle, Taylan Özgür Sezer, Valentina Mengardo, V Concepción Martín, Vanessa Wills, Vikki Owen-Holt, Viviana Casagrande, Waleed Al‐Khyatt, Wilma Jansen, Wei Wang, Wietse J. Eshuis, Wojciech Polkowski, Xi Huang, Xiaodong Wang, Xueyin Chen, Y Gonzalez Dominguez, Alex Wang, Y K S Viswanath, Yingli He, Zeynep Demir, Z Na,
Abstract Background Surgery is the primary treatment that can offer potential cure for gastric cancer, but is associated with significant risks. Identifying optimal surgical approaches should be based on comparing outcomes from well designed trials. Currently, trials report different outcomes, making synthesis of evidence difficult. To address this, the aim of this study was to develop a core outcome set (COS)—a standardized group of outcomes important to key international stakeholders—that should ...
Oxford University Press
Produção Nacional
Revisado por pares
William Fedrigo, Washington Peres Núñez, Gabriel Grassioli Schreinert, Thaís Radünz Kleinert, Matheus Ferreira Matuella, Mario Castaneda-Lopez, Jorge Augusto Pereira Ceratti,
This paper evaluates the flexural static and cyclic behaviour of cement-treated mixtures of reclaimed asphalt pavement (RAP) and lateritic soil (LS). Flexural strength and resilient modulus increased with RAP percentage. Strain at break increased with higher RAP and lower cement amounts, increasing mixtures flexibility. Higher cement contents led to stronger and stiffer mixtures. Strain-based fatigue relationships were obtained. Mechanistic analyses showed that the fatigue life of cement-treated recycled ...
Tópico(s): Geotechnical Engineering and Underground Structures
2019 - Taylor & Francis | Road Materials and Pavement Design
Guadalupe Palacios-Núñez, Gabriel Vélez Cuartas, Juan D. Botero,
Intellectual property became a relevant academic cross-disciplinary field in an international context with the demand for the global governance of knowledge. However, the degree of consolidation of cross-disciplinary academic communities is not clear. To determine how closely related are these communities, this paper proposes a mixed methodology to find invisible colleges in the production of intellectual property. Scientific articles from 1994 to 2016 were extracted from web of science, taking ...
Tópico(s): Innovation Policy and R&D
2018 - Springer Nature (Netherlands) | Scientometrics
Produção Nacional
Revisado por pares
Andrés Mauricio Pinzón-Núñez, Gabriel Alfonso Alvarez Rodríguez, Fernando Pereira Monteiro, Amanda Flausino de Faria, Júlio Carlos Pereira da Silva, Ana Cristina Andrade Monteiro, Carolina Valeriano de Carvalho, Luíz Antônio Augusto Gomes, Ricardo Magela de Souza, Jorge Teodoro de Souza, Flávio Henrique Vasconcelos de Medeiros,
Black rot of crucifers, (Xanthomonas campestris pv. campestris) is the principal yield-limiting and destructive pathogen of cruciferous crop worldwide. In order to validate a bio-based control alternative for this disease, whey, lime sulfur, biofertilizer, Bordeaux mixture or raw milk were applied to kale (Brassica oleracea var. acephala) plants. The disease control was achieved by most of the tested products. Milk-based products (raw milk and whey) and biofertilizer reduced the severity by 44 and ...
Tópico(s): Agronomic Practices and Intercropping Systems
2018 - Nature Portfolio | Scientific Reports
Carlos Nava-Zuazo, Fabiola Chávez-Silva, Rosa Moo‐Puc, Manuel Jesús Chan-Bacab, Benjamín Otto Ortega-Morales, Hermenegilda Moreno‐Díaz, Daniel Dı́az-Coutiño, Emanuel Hernández‐Núñez, Gabriel Navarrete‐Vázquez,
The 2-acylamino-5-nitro-1,3-thiazole derivatives (1–14) were prepared using a one step reaction. All compounds were tested in vitro against four neglected protozoan parasites (Giardia intestinalis, Trichomonas vaginalis, Leishmania amazonensis and Trypanosoma cruzi). Acetamide (9), valeroylamide (10), benzamide (12), methylcarbamate (13) and ethyloxamate (14) derivatives were the most active compounds against G. intestinalis and T. vaginalis, showing nanomolar inhibition. Compound 13 (IC50 = 10 nM), was 536- ...
Tópico(s): Coccidia and coccidiosis research
2014 - Elsevier BV | Bioorganic & Medicinal Chemistry
Manuel Jesús Chan-Bacab, Emanuel Hernández‐Núñez, Gabriel Navarrete‐Vázquez,
Sir, Parasitic diseases such as leishmaniasis and trypanosomiasis, both caused by protozoan parasites of the Kinetoplastida order, represent a serious problem to the health and the economy of many developing countries. The Leishmania species cause a variety of diseases, from self-healing cutaneous lesions to lifethreatening visceral infections. Clinical manifestations depend on the species of the infecting parasites. There are an estimated annual 1.5–2.0 million new cases of leishmaniasis, of which ...
Tópico(s): Trypanosoma species research and implications
2009 - Oxford University Press | Journal of Antimicrobial Chemotherapy