Francesco Girardi, Gaetano De Gennaro, Lucio Colizzi, Vito Nicola Convertini,
New types of patient health records aim to help physicians shift from a medical practice, often based on their personal experience, towards one of evidence based medicine, thus improving the communication among patients and care providers and increasing the availability of personal medical information. These new records, allowing patients and care providers to share medical data and clinical information, and access them whenever they need, can be considered enabling Ambient Assisted Living technologies. ...
Tópico(s): Artificial Intelligence in Healthcare and Education
2020 - Multidisciplinary Digital Publishing Institute | Electronics
Stefania Staibano, Massimo Mascolo, Francesco Paolo Mancini, Annamaria Kisslinger, Gaetano Salvatore, Maria Benedetto, Paolo Chieffi, Vincenzo Altieri, Domenico Prezioso, Gennaro Ilardi, Gaetano De Rosa, Donatella Tramontano,
Prostatic cancer may remain organ-confined indefinitely; in a number of patients, however it gives rise to clinical symptoms and death. The biological behaviour of this tumour mostly remains difficult to predict. A promising tool for diagnosis and prognosis of some human tumours is the chromatin assembly factor-1 (CAF-1), involved in the control of higher order chromatin organization. The aim was to explore the role of CAF-1/p60 protein as a new prognostic marker for prostatic cancer.The expression ...
Tópico(s): Cancer, Lipids, and Metabolism
2009 - Wiley | Histopathology
Lorenzo Lo Muzio, Michele Davide Mignogna, Giuseppe Pannone, Corrado Rubini, Felice Roberto Grassi, Pier Francesco Nocini, Filomena Ferrari, R Serpico, Gennaro Favia, Gaetano De Rosa, Eugenio Maiorano,
Apoptosis is a genetically determined process playing an active role in tissue size regulation, morphogenesis and removing damaged cells that could be potentially dangerous for their host. Several agents involved in apoptosis regulation, such as the bcl-2 family components, act as oncogenes and are involved in oral carcinogenesis. Aim of this study is to explore bcl-2 immunoreactivity in oral cancers and to assess its potential clinico-pathological implications. Ninety oral squamous cell carcinoma ...
Tópico(s): RNA Interference and Gene Delivery
2003 - Elsevier BV | Oncology Reports
Libuse Tauchmanovà, Bianca Serio, Antonio Del Puente, Antonio M. Risitano, Antonella Esposito, Gennaro De Rosa, Gaetano Lombardi, Annamaria Colao, Bruno Rotoli, Carmine Selleri,
Bone complications after allogeneic stem cell transplant (allo-SCT) include osteoporosis, fractures, and osteonecrosis. We investigated bone abnormalities in long-term survivors after busulfan cyclophosphamide-conditioning regimen, followed by human leukocyte antigen-identical sibling SCT. Bone density was measured by dual-energy x-ray absorptiometry at lumbar spine (LS) and femoral neck (FN) and phalangeal osteosonogrammetry (OSG) in 41 patients 1–10 yr after allo-SCT. Using colony-forming units-fibroblast ( ...
Tópico(s): Hemoglobinopathies and Related Disorders
2002 - Oxford University Press | The Journal of Clinical Endocrinology & Metabolism
L. Palleschi, Francesco Vetta, E. De Gennaro, Gaetano Idone, G. Sottosanti, Walter Gianni, Vincenzo Marigliano,
Tópico(s): Dementia and Cognitive Impairment Research
1996 - Elsevier BV | Archives of Gerontology and Geriatrics
Augusto Di Castelnuovo, Raffaele De Caterina, Giovanni de Gaetano, Licia Iacoviello,
... C, Crosta F, Danzi G, D'Ardes D, de Gaetano Donati K, Di Gennaro F, Di Tano G, D'Offizi G, Fantoni ... Dal Pra C, Danzi G, D'Ardes D, de Gaetano Donati K, Di Gennaro F, Di Tano G, D'Offizi G, Filippini ... A, Crosta F, Danzi G, D'Ardes D, de Gaetano Donati K, Di Gennaro F, Di Tano G, D'Offizi G, Fusco ...
Tópico(s): COVID-19 Impact on Reproduction
2020 - Lippincott Williams & Wilkins | Hypertension
Stefania Staibano, Massimo Mascolo, Gennaro Ilardi, Maria Siano, Gaetano De Rosa,
FKBP51 is a FK506-binding immunophilin involved in the regulation of several fundamental biological processes. A growing body of data indicates that this protein has also a role in the abnormal cell growth of cancers, and could be considered as a promising new marker of tumor progression and response to radio/chemotherapy. However, the data concerning the expression of FKBP51 in cancer are not conclusive, and partially contradictory. They delineate a very complex scenario, in which many molecular ...
Tópico(s): Toxin Mechanisms and Immunotoxins
2011 - Elsevier BV | Current Opinion in Pharmacology
Marco Favaro, Stefano Agnoli, Mattia Cattelan, Alessandro Moretto, Christian Durante, Silvia Leonardi, Julia Kunze‐Liebhäuser, Oliver Schneider, Armando Gennaro, Gaetano Granozzi,
The ability to control the three-dimensional architecture of graphene-based materials following a rational design is essential for technological applications. Here we demonstrate that the electrochemical etching can be used as a surgical tool to tailor the morphology of graphene electrodes and to impart special features, like micrometric channels and controlled mesoporosity (foams). The final materials, thanks to the high surface area, can represent a promising class of carbon-based supercapacitors. ...
Tópico(s): Supercapacitor Materials and Fabrication
2014 - Elsevier BV | Carbon
Angela De Palma, Mirko Girolamo Cantatore, Francesco Di Gennaro, Francesca Del Signore, Teodora Panza, Debora Brascia, Giulia De Iaco, Doroty Sampietro, Rosatea Quercia, Marcella Genualdo, Ondina Pizzuto, Giuseppe Garofalo, Fabio Signorile, Davide Fiore Bavaro, Gaetano Brindicci, Nicolò De Gennaro, Annalisa Saracino, Nicola Quaranta, Gianfranco Favia, Giuseppe Marulli,
Descending necrotizing mediastinitis (DNM) is an acute, rare, severe condition with high mortality, but the optimal management protocol is still controversial. We retrospectively analyzed the results of multidisciplinary management in patients treated for DNM at our center over the last twenty years. Fifteen male patients, mean age 49.07 ± 14.92 years, were treated: 9 with cervico-pharyngeal etiopathogenesis, 3 peri-tonsillar/tonsillar, 2 odontogenic, 1 post-surgical; 6 with DNM type I, 6 with type ...
Tópico(s): Infectious Diseases and Tuberculosis
2022 - Multidisciplinary Digital Publishing Institute | Antibiotics
Domenico Luca Grieco, Gabriele Pintaudi, Filippo Bongiovanni, Gian Marco Anzellotti, Luca S. Menga, Melania Cesarano, Antonio Maria Dell’Anna, Tommaso Rosà, Luca Delle Cese, Giuseppe Bello, Valentina Giammatteo, Veronica Gennenzi, Eloisa Sofia Tanzarella, Salvatore Lucio Cutuli, Gennaro De Pascale, Andrea De Gaetano, Salvatore Maurizio Maggiore, Massimo Antonelli,
Background Positive end-expiratory pressure (PEEP) benefits in acute respiratory distress syndrome are driven by lung dynamic strain reduction. This depends on the variable extent of alveolar recruitment. The recruitment-to-inflation ratio estimates recruitability across a 10–cm H2O PEEP range through a simplified maneuver. Whether recruitability is uniform or not across this range is unknown. The hypotheses of this study are that the recruitment-to-inflation ratio represents an accurate estimate ...
Tópico(s): Mechanical Circulatory Support Devices
2023 - Lippincott Williams & Wilkins | Anesthesiology
Davide Fiore Bavaro, Roberta Papagni, Alessandra Belati, Lucia Diella, Antonio De Luca, Gaetano Brindicci, Nicolò De Gennaro, Francesco Di Gennaro, Federica Romanelli, Stefania Stolfa, Luigi Ronga, Adriana Mosca, Francesco Pomarico, Maria Dell’Aera, Monica Stufano, Lidia Dalfino, Salvatore Grasso, Annalisa Saracino,
Bloodstream infections (BSI) caused by carbapenem-resistant Acinetobacter baumannii (CRAB) are associated with high mortality with limited treatment. The aim of this study is to compare effectiveness and safety of colistin-based versus cefiderocol-based therapies for CRAB-BSI.This is a retrospective observational study enrolling patients with monomicrobial CRAB-BSIs treated with colistin or cefiderocol from 1 January 2020, to 31 December 2022. The 30-day all-cause mortality rate was the primary outcome. ...
Tópico(s): Pneumonia and Respiratory Infections
2023 - Adis, Springer Healthcare | Infectious Diseases and Therapy
Michele Zanatta, Laura Calvillo, Jian Zheng, Gian Andrea Rizzi, Christian Durante, Giuseppe Giallongo, Dymitrov Chirkov, Luciano Colazzo, Carla Marega, Armando Gennaro, Gaetano Granozzi,
Cu2O nanoparticles have been grown by pulse-electrochemical deposition on a Digital Versatile Disk (DVD) which acts as a nanostructured electrode. Prior to Cu2O deposition, the silver-coated rectangular-shaped grooves of the disassembled DVD were coated with a TiO2 thin film by a modified sol–gel method, where oxalic acid is used in place of the usual mineral acids to peptize the precipitated hydrous titania formed from the hydrolysis of titanium iso-propoxide. This procedure leaves no inorganic ...
Tópico(s): ZnO doping and properties
2016 - Elsevier BV | Thin Solid Films
Gennaro Galasso, Gaetano Santulli, Federico Piscione, Roberta De Rosa, Valentina Trimarco, Raffaele Piccolo, Salvatore Cassese, Guido Iaccarino, Bruno Trimarco, Massimo Chiariello,
The clinical impact of PlA2 polymorphism has been investigated in several diseases, but the definition of its specific role on thrombotic cardiovascular complications has been challenging. We aimed to explore the effect of PlA2 polymorphism on outcome in patients with atherosclerosis.We studied 400 consecutive patients with coronary artery disease (CAD) undergoing percutaneous coronary intervention. A replication study was conducted in 74 hypertensive patients with cerebrovascular events while a ...
Tópico(s): Cardiovascular Function and Risk Factors
2010 - BioMed Central | BMC Cardiovascular Disorders
Massimo Mascolo, Maria Siano, Gennaro Ilardi, Daniela Russo, Francesco Merolla, Gaetano De Rosa, Stefania Staibano,
Squamous cell carcinoma of the oral region (OSCC) is one of the most common and highly aggressive malignancies worldwide, despite the fact that significant results have been achieved during the last decades in its detection, prevention and treatment. Although many efforts have been made to define the molecular signatures that identify the clinical outcome of oral cancers, OSCC still lacks reliable prognostic molecular markers. Scientific evidence indicates that transition from normal epithelium to ...
Tópico(s): RNA modifications and cancer
2012 - Multidisciplinary Digital Publishing Institute | International Journal of Molecular Sciences
G. Russo, Gaetano Alessandro Vivaldi, Bernardo De Gennaro, Salvatore Camposeo,
Recent olive cultivation in Mediterranean Countries is characterised by the strong diffusion of high-density cropping systems and by the most environmentally conscious management regarding all the agronomic practices and the waste disposal as well. This research has investigated the possibility of the use of De-Oiled Pomace (DOP) as an eco-friendly tool for weed control in a high-density olive orchard providing an environmental comparison with other soil management techniques. Five methods of weed ...
Tópico(s): Edible Oils Quality and Analysis
2014 - Elsevier BV | Journal of Cleaner Production
Natale Daniele Brunetti, Lucia Bisceglia, Giulia Dellegrottaglie, Angela Ivana Bruno, Gaetano Di Pietro, Luisa De Gennaro, Matteo Di Biase,
The extension of necrotic zone and event-free survival in patients with acute myocardial infarction (AMI) is significantly driven by time to reperfusion [ 1 Francone M. Bucciarelli-Ducci C. Carbone I. Canali E. Scardala R. Calabrese F.A. Sardella G. Mancone M. Catalano C. Fedele F. Passariello R. Bogaert J. Agati L. Impact of primary coronary angioplasty delay on myocardial salvage, infarct size, and microvascular damage in patients with ST-segment elevation myocardial infarction: insight from cardiovascular ...
Tópico(s): Cardiac Imaging and Diagnostics
2015 - Elsevier BV | International Journal of Cardiology
Stanislovas S. Jankauskas, Pasquale Mone, Roberta Avvisato, Fahimeh Varzideh, Stefano De Gennaro, Luigi Salemme, Gaetano Macina, Urna Kansakar, Angelo Cioppa, Salvatore Frullone, Jessica Gambardella, Marco Di Mauro, Tullio Tesorio, Gaetano Santulli,
Cardiac fibrosis represents a key element in the pathophysiology of heart failure with preserved ejection fraction (HFpEF), a condition highly prevalent amongst geriatric patients, especially if diabetic. The microRNA 181c (miR-181c) has been shown to be associated with the response to exercise training in HFpEF patients and has been also linked to diabetic cardiovascular complications. However, the underlying mechanisms have not been fully elucidated. To measure circulating miR-181c in elderly patients ...
Tópico(s): Cardiac Fibrosis and Remodeling
2023 - Elsevier BV | Mechanisms of Ageing and Development
Pasquale Mone, Angela Lombardi, Urna Kansakar, Fahimeh Varzideh, Stanislovas S. Jankauskas, Antonella Pansini, Stefania Marzocco, Stefano De Gennaro, Michele Famiglietti, Gaetano Macina, Salvatore Frullone, Gaetano Santulli,
Endothelial dysfunction represents a key mechanism underlying heart failure with preserved ejection fraction (HFpEF), diabetes mellitus (DM), and frailty. However, reliable biomarkers to monitor endothelial dysfunction in these patients are lacking. In this study, we evaluated the expression of a panel of circulating microRNAs (miRs) involved in the regulation of endothelial function in frail older adults with HFpEF and DM that were treated for 3 months with empagliflozin, metformin, or insulin. We ...
Tópico(s): MicroRNA in disease regulation
2022 - American Society for Pharmacology and Experimental Therapeutics | Journal of Pharmacology and Experimental Therapeutics
Vincenzo Patella, Gennaro de Crescenzo, B Lamparter-Schummert, Gaetano De Rosa, M. Adt, Giancarlo Marone,
Tópico(s): Cardiac Fibrosis and Remodeling
1997 - Springer Science+Business Media | Inflammation Research
Andrea Conversano, Francesco Melillo, Antonio Napolano, Evgeny Fominskiy, Marzia Spessot, Fabio Ciceri, Eustachio Agricola,
... A, Crosta F, Danzi G, D'Ardes D, de Gaetano Donati K, Di Gennaro F, Di Tano G, D'Offizi G, Fusco ...
Tópico(s): Long-Term Effects of COVID-19
2020 - Lippincott Williams & Wilkins | Hypertension
Walter Ageno, Erica De Candia, Licia Iacoviello, Augusto Di Castelnuovo,
... Crosta, 30Gian Battista Danzi, 11Damiano D'Ardes, 6Katleen de Gaetano Donati, 31Francesco Di Gennaro, 30Giuseppe Di Tano,32Gianpiero D'Offizi, 6,7Massimo ...
Tópico(s): Atrial Fibrillation Management and Outcomes
2021 - Elsevier BV | Thrombosis Research
Filomena de Nigris, Licciana Zanella, Francesco Cacciatore, A. Chiara, Flavio Fazioli, Gennaro Chiappetta, Gaetano Apice, Teresa Infante, Mario Monaco, Raffaele Rossiello, Gaetano De Rosa, Marco Alberghini, Claudio Napoli,
Abstract Background The polycomb transcription factor Yin Yang 1 (YY1) overexpression can be causally implicated in experimental tumor growth and metastasization. To date, there is no clinical evidence of YY1 involvement in outcome of patients with osteosarcoma. Prognosis of osteosarcoma is still severe and only few patients survive beyond five years. We performed a prospective immunohistochemistry analysis to correlate YY1 immunostaining with metastatic development and survival in a selected homogeneous ...
Tópico(s): Multiple Myeloma Research and Treatments
2011 - BioMed Central | BMC Cancer
Antonio Giorgio, Pietro Amoroso, P Fico, Gennaro Lettieri, L. Finelli, Ciorgio de Stefano, Gaetano Pesce, Vincenzo Scala, Paola Pierri, G Pierri,
Abstract Seven hundred ninety‐one consecutive patients with acute viral hepatitis, 17 of whom had liver failure, and 97 healthy volunteers were examined by ultrasound. No specific patterns were found in either the uncomplicated or the complicated forms. Only 19 subjects showed a typical “bright liver” pattern, which is correlated with significant vacuolar hepatocellular degeneration. The increased brightness and clear visualization of portal vein radicle walls, previously described in this disease, ...
Tópico(s): Animal Virus Infections Studies
1986 - Wiley | Journal of Clinical Ultrasound
Libuse Tauchmanovà, Carmine Selleri, Gennaro De Rosa, Loredana Pagano, Francesco Orio, Gaetano Lombardi, Bruno Rotoli, Annamaria Colao,
The progressively increasing number of long-term survivors after allogeneic bone marrow transplantation (allo-BMT) led researchers to focus on the early and late complications of this procedure. Endocrine dysfunction occurred mostly in patients who had undergone total body irradiation (TBI) as part of pretransplantation treatment. The extent to which chemotherapy and immune system derangement affect endocrine function in allo-BMT recipients is still unclear.Forty consecutive patients (21 women, 19 ...
Tópico(s): Childhood Cancer Survivors' Quality of Life
2002 - Wiley | Cancer
L. Tauchmanovà, Giuseppe Matarese, Carlo Carella, Gennaro De Rosa, Bianca Serio, Patrizia Ricci, Gaetano Lombardi, Bruno Rotoli, Annamaria Colao, Carmine Selleri,
Background. Increased serum leptin has been described after various organ transplants, with a mechanism that is still unclear. Methods. We measured serum leptin in 60 patients before and after allogeneic (allo) or autologous (auto) stem cell transplant (SCT) and in 60 healthy controls, matched for age and body mass index (BMI). Results. Serum leptin was higher in patients after SCT than before and in controls. Leptin production was higher after allo- than after auto-SCT; the presence of chronic graft- ...
Tópico(s): Biochemical Analysis and Sensing Techniques
2004 - Wolters Kluwer | Transplantation
Giuseppe Giallongo, Roberto Pilot, Christian Durante, Gian Andrea Rizzi, Raffaella Signorini, Renato Bozio, Armando Gennaro, Gaetano Granozzi,
Tópico(s): Quantum Dots Synthesis And Properties
2011 - Springer Science+Business Media | Plasmonics
Augusto Di Castelnuovo, Simona Costanzo, Andrea Antinori, Nausicaa Berselli, Lorenzo Blandi, Marialaura Bonaccio, Roberto Cauda, Alessandro Gialluisi, Giovanni Guaraldi, Lorenzo Menicanti, Marco Mennuni, Roberta Mussinelli, Ilaria My, Giustino Parruti, Giuseppe Patti, Stefano Perlini, Francesca Santilli, Carlo Signorelli, Giulio Stefanini, Alessandra Vergori, Pasquale Abete, Walter Ageno, Piergiuseppe Agostoni, Luca Maria Aiello, Samir Al Moghazi, Rosa Arboretti, Filippo Aucella, Greta Barbieri, Martina Barchitta, Alessandro Bartoloni, Paolo Bonfanti, Francesco Cacciatore, Lucia Caiano, Laura Carrozzi, Antonio Cascio, Giacomo Castiglione, Stefania Cianfrone, Arturo Ciccullo, Antonella Cingolani, Francesco Cipollone, Claudia Colomba, Cristina Colombo, Ottavia Cozzi, Annalisa Crisetti, Francesca Crosta, Gian Battista Danzi, Damiano D’Ardes, Katleen de Gaetano Donati, Francesco Di Gennaro, Giuseppe Di Tano, Gianpiero D’Offizi, Francesco Maria Fusco, Ivan Gentile, Emauele Graziani, Gabriella Guarnieri, Giovanni Larizza, Armando Leone, Veronica Lio, Mothanje Barbara Lucia, Gloria Maccagni, Ferruccio Madaro, Stefano Maitan, Sandro Mancarella, Rosa Manuele, Massimo Mapelli, Riccardo Maragna, Rossella Marcucci, Giulio Maresca, Silvia Marongiu, Claudia Marotta, Lorenzo Marra, Franco Mastroianni, Maria Mazzitelli, Alessandro Mengozzi, Francesco Menichetti, Marianna Meschiari, Jovana Milić, Filippo Minutolo, Béatrice Molena, Cristina Mussini, Maria Musso, Anna Odone, Marco Olivieri, Antonella Palimodde, Emanuela Pasi, Raffaele Pesavento, Francesco Petri, Biagio Pinchera, Carlo Andrea Pivato, Venerino Poletti, Claudia Ravaglia, Marco Rossato, Marianna Rossi, Anna Sabena, Francesco Salinaro, Vincenzo Sangiovanni, Carlo Sanrocco, Giancarlo Scoppettuolo, Laura Scorzolini, Raffaella Sgariglia, Paola Simeone, Enrico Maria Trecarichi, Roberto Vettor, Andrea Vianello, Marco Vinceti, Alexandra Virano, Laura Vocciante, Raffaele De Caterina, Licia Iacoviello,
The hypothesis that been set forward that use of Renin Angiotensin Aldosterone System (RAAS) inhibitors is associated with COVID−19 severity. We set-up a multicenter Italian collaboration (CORIST Project, ClinicalTrials.gov ID: NCT04318418) to retrospectively investigate the relationship between RAAS inhibitors and COVID−19 in-hospital mortality. We also carried out an updated meta-analysis on the relevant studies. We analyzed 4069 unselected patients with laboratory-confirmed SARS-CoV-2 infection ...
Tópico(s): COVID-19 and Mental Health
2020 - Elsevier BV | Vascular Pharmacology
Augusto Di Castelnuovo, Marialaura Bonaccio, Simona Costanzo, Alessandro Gialluisi, Andrea Antinori, Nausicaa Berselli, Lorenzo Blandi, Raffaele Bruno, Roberto Cauda, Giovanni Guaraldi, Ilaria My, Lorenzo Menicanti, Giustino Parruti, Giuseppe Patti, Stefano Perlini, Francesca Santilli, Carlo Signorelli, Giulio Stefanini, Alessandra Vergori, Amina Abdeddaim, Walter Ageno, Antonella Agodi, Piergiuseppe Agostoni, Luca Maria Aiello, Samir Al Moghazi, Filippo Aucella, Greta Barbieri, Alessandro Bartoloni, Carolina Bologna, Paolo Bonfanti, Serena Brancati, Francesco Cacciatore, Lucia Caiano, F. Cannata, Laura Carrozzi, Antonio Cascio, Antonella Cingolani, Francesco Cipollone, Claudia Colomba, Annalisa Crisetti, Francesca Crosta, Gian Battista Danzi, Damiano D’Ardes, Katleen de Gaetano Donati, Francesco Di Gennaro, Gisella Di Palma, Giuseppe Di Tano, Massimo Fantoni, Tommaso Filippini, Paola Fioretto, Francesco Maria Fusco, Ivan Gentile, Leonardo Grisafi, Gabriella Guarnieri, Francesco Landi, Giovanni Larizza, Armando Leone, Gloria Maccagni, Sandro Maccarella, Massimo Mapelli, Riccardo Maragna, Rossella Marcucci, Giulio Maresca, Claudia Marotta, Lorenzo Marra, Franco Mastroianni, Alessandro Mengozzi, Francesco Menichetti, Jovana Milić, Rita Murri, Arturo Montineri, Roberta Mussinelli, Cristina Mussini, Maria Musso, Anna Odone, Marco Olivieri, Emanuela Pasi, Francesco Petri, Biagio Pinchera, Carlo Andrea Pivato, Roberto Pizzi, Venerino Poletti, Francesca Raffaelli, Claudia Ravaglia, Giulia Righetti, Andrea Rognoni, Marco Rossato, Marianna Rossi, Anna Sabena, Francesco Salinaro, Vincenzo Sangiovanni, Carlo Sanrocco, Antonio Scarafino, Laura Scorzolini, Raffaella Sgariglia, Paola Simeone, Enrico Guido Spinoni, Carlo Torti, Enrico Maria Trecarichi, Francesca Vezzani, Giovanni Veronesi, Roberto Vettor, Andrea Vianello, Marco Vinceti, Raffaele De Caterina, Licia Iacoviello,
Background and aimsThere is poor knowledge on characteristics, comorbidities and laboratory measures associated with risk for adverse outcomes and in-hospital mortality in European Countries. We aimed at identifying baseline characteristics predisposing COVID-19 patients to in-hospital death.Methods and resultsRetrospective observational study on 3894 patients with SARS-CoV-2 infection hospitalized from February 19th to May 23rd, 2020 and recruited in 30 clinical centres distributed throughout Italy. ...
Tópico(s): Long-Term Effects of COVID-19
2020 - Elsevier BV | Nutrition Metabolism and Cardiovascular Diseases
Augusto Di Castelnuovo, Simona Costanzo, Andrea Antinori, Nausicaa Berselli, Lorenzo Blandi, Marialaura Bonaccio, Roberto Cauda, Giovanni Guaraldi, Lorenzo Menicanti, Marco Mennuni, Giustino Parruti, Giuseppe Patti, Francesca Santilli, Carlo Signorelli, Alessandra Vergori, Pasquale Abete, Walter Ageno, Antonella Agodi, Piergiuseppe Agostoni, Luca Maria Aiello, Samir Al Moghazi, Rosa Arboretti, Marinella Astuto, Filippo Aucella, Greta Barbieri, Alessandro Bartoloni, Paolo Bonfanti, Francesco Cacciatore, Lucia Caiano, Laura Carrozzi, Antonio Cascio, Arturo Ciccullo, Antonella Cingolani, Francesco Cipollone, Claudia Colomba, Cristina Colombo, Francesca Crosta, Gian Battista Danzi, Damiano D’Ardes, Katleen de Gaetano Donati, Francesco Di Gennaro, Giuseppe Di Tano, Gianpiero D’Offizi, Massimo Fantoni, Francesco Maria Fusco, Ivan Gentile, Francesco Gianfagna, Elvira Grandone, Emauele Graziani, Leonardo Grisafi, Gabriella Guarnieri, Giovanni Larizza, Armando Leone, Gloria Maccagni, Ferruccio Madaro, Stefano Maitan, Sandro Mancarella, Massimo Mapelli, Riccardo Maragna, Rossella Marcucci, Giulio Maresca, Silvia Marongiu, Claudia Marotta, Lorenzo Marra, Franco Mastroianni, Maria Mazzitelli, Alessandro Mengozzi, Francesco Menichetti, Marianna Meschiari, Jovana Milić, Filippo Minutolo, Béatrice Molena, Arturo Montineri, Cristina Mussini, Maria Musso, Daniela Niola, Anna Odone, Marco Olivieri, Antonella Palimodde, Roberta Parisi, Emanuela Pasi, Raffaele Pesavento, Francesco Petri, Biagio Pinchera, Venerino Poletti, Claudia Ravaglia, Andrea Rognoni, Marco Rossato, Marianna Rossi, Vincenzo Sangiovanni, Carlo Sanrocco, Laura Scorzolini, Raffaella Sgariglia, Paola Simeone, Eleonora Taddei, Carlo Torti, Roberto Vettor, Andrea Vianello, Marco Vinceti, Alexandra Virano, Laura Vocciante, Raffaele De Caterina, Licia Iacoviello,
Abstract Introduction A hypercoagulable condition was described in patients with coronavirus disease 2019 (COVID-19) and proposed as a possible pathogenic mechanism contributing to disease progression and lethality. Aim We evaluated if in-hospital administration of heparin improved survival in a large cohort of Italian COVID-19 patients. Methods In a retrospective observational study, 2,574 unselected patients hospitalized in 30 clinical centers in Italy from February 19, 2020 to June 5, 2020 with ...
Tópico(s): Long-Term Effects of COVID-19
2021 - Thieme Medical Publishers (Germany) | Thrombosis and Haemostasis
Augusto Di Castelnuovo, Simona Costanzo, Andrea Antinori, Nausicaa Berselli, Lorenzo Blandi, Marialaura Bonaccio, Raffaele Bruno, Roberto Cauda, Alessandro Gialluisi, Giovanni Guaraldi, Lorenzo Menicanti, Marco Mennuni, Ilaria My, Agostino Parruti, Giuseppe Patti, Stefano Perlini, Francesca Santilli, Carlo Signorelli, Giulio Stefanini, Alessandra Vergori, Walter Ageno, Luca Maria Aiello, Piergiuseppe Agostoni, Samir Al Moghazi, Rosa Arboretti, Filippo Aucella, Greta Barbieri, Martina Barchitta, Alessandro Bartoloni, Carolina Bologna, Paolo Bonfanti, Lucia Caiano, Laura Carrozzi, Antonio Cascio, Giacomo Castiglione, Mauro Chiarito, Arturo Ciccullo, Antonella Cingolani, Francesco Cipollone, Claudia Colomba, Cristina Colombo, Francesco Crosta, Giovanni Dalena, Chiara Dal Prà, Gian Battista Danzi, Damiano D’Ardes, Katleen de Gaetano Donati, Francesco Di Gennaro, Giuseppe Di Tano, Gianpiero D’Offizi, Tommaso Filippini, Francesco Maria Fusco, Carlo Gaudiosi, Ivan Gentile, Giancarlo Gini, Elvira Grandone, Gabriella Guarnieri, Gennaro L. F. Lamanna, Giovanni Larizza, Armando Leone, Veronica Lio, Angela Raffaella Losito, Gloria Maccagni, Stefano Maitan, Sandro Mancarella, Rosa Manuele, Massimo Mapelli, Riccardo Maragna, Lorenzo Marra, Giulio Maresca, Claudia Marotta, Franco Mastroianni, Maria Mazzitelli, Alessandro Mengozzi, Francesco Menichetti, Jovana Milić, Filippo Minutolo, Béatrice Molena, Roberta Mussinelli, Cristina Mussini, Maria Musso, Anna Odone, Marco Olivieri, Emanuela Pasi, Annalisa Perroni, Francesco Petri, Biagio Pinchera, Carlo Andrea Pivato, Venerino Poletti, Claudia Ravaglia, Marco Rossato, Marianna Rossi, Anna Sabena, Francesco Salinaro, Vincenzo Sangiovanni, Carlo Sanrocco, Laura Scorzolini, Raffaella Sgariglia, Paola Simeone, Michele Spinicci, Enrico Maria Trecarichi, Giovanni Veronesi, Roberto Vettor, Andrea Vianello, Marco Vinceti, Elena Visconti, Laura Vocciante, Raffaele De Caterina, Licia Iacoviello,
Background: Protease inhibitors have been considered as possible therapeutic agents for COVID-19 patients. Objectives: To describe the association between lopinavir/ritonavir (LPV/r) or darunavir/cobicistat (DRV/c) use and in-hospital mortality in COVID-19 patients. Study Design: Multicenter observational study of COVID-19 patients admitted in 33 Italian hospitals. Medications, preexisting conditions, clinical measures, and outcomes were extracted from medical records. Patients were retrospectively ...
Tópico(s): Long-Term Effects of COVID-19
2021 - Frontiers Media | Frontiers in Medicine