Árpád Pusztai, J.F.J.G. Koninkx, Henno Hendriks, Wouter Kok, Saskia Hulscher, Els J. M. Van Damme, Willy J. Peumans, George Grant, Susan Bardócz,
... assess whether the presently most favored insecticidal lectin, Galanthus nivalis agglutinin, would be harmful for mammals. Effects of Galanthus nivalis agglutinin on gut and brush border enzymes were ... did not reduce the growth of young rats, Galanthus nivalis agglutinin had negligible effects on the weight and ... in gut metabolism caused by the incorporation of Galanthus nivalis agglutinin in the diet were less extensive than ... to establish whether it is safe to use Galanthus nivalis agglutinin in transgenic plants destined for human consumption.
Tópico(s): Plant tissue culture and regeneration
1996 - Elsevier BV | The Journal of Nutritional Biochemistry
Florian Tribl, Manfred Gerlach, Katrin Marcus, Esther Asan, Thomas Tatschner, Thomas Arzberger, Helmut E. Meyer, Gerhard Bringmann, Peter Riederer,
... one-dimensional; LAMP, lysosome-associated membrane glycoprotein; GNA, Galanthus nivalis agglutinin; LIMP, lysosome membrane protein; ER, endoplasmic reticulum; ... one-dimensional; LAMP, lysosome-associated membrane glycoprotein; GNA, Galanthus nivalis agglutinin; LIMP, lysosome membrane protein; ER, endoplasmic reticulum; ... and cathepsin B were purchased from Calbiochem. Biotinylated Galanthus nivalis agglutinin (GNA) and horseradish peroxidase-linked streptavidin were ... of a mannose-specific lectin from the snowdrop (Galanthus nivalis) bulb.J. Biol. Chem. 1988; 263: 728-734Google ...
Tópico(s): Connexins and lens biology
2005 - Elsevier BV | Molecular & Cellular Proteomics
Keiko Fukushima, Katsuko Yamashita,
... IL-2 receptor α subunit was stained with Galanthus nivalis agglutinin which specifically recognizes high-mannose type glycans. ... IL-2 receptor α subunit was stained with Galanthus nivalis agglutinin which specifically recognizes high-mannose type glycans. ... N-acetylglucosaminidase H endo-β-N-acetylglucosaminidase D Galanthus nivalis agglutinin recombinant human interleukin-2 polyacrylamide gel electrophoresis ... only the IL-2Rα subunit was stained with Galanthus nivalis agglutinin (GNA) which specifically recognizes high-mannose type ...
Tópico(s): Fungal Infections and Studies
2001 - Elsevier BV | Journal of Biological Chemistry
... Effect of diets containing genetically modified potatoes expressing Galanthus nivalis lectin on rat small intestineDiets containing genetically modified (GM) potatoes expressing the lectin Galanthus nivalis agglutinin (GNA) had variable effects on different parts ... potential risks to human health of the lectin Galanthus nivalis agglutinin (GNA), a compound that may be useful ...
Tópico(s): Nutrition, Genetics, and Disease
1999 - Elsevier BV | The Lancet
Els J. M. Van Damme, Irwin Goldstein, Willy J. Peumans,
... Narcissus pseudonarcissus and Clivia miniata) or tetramers (in Galanthus nivalis, Hippeastrum hybrid, Allium cepa and A. porrum. Most ... Alliaceae bulbs. Antisera raised in rabbits against the Galanthus nivalis and the Narcissus cv Carlton lectins gave, upon ... same assay was carried out with antiserum against Galanthus nivalis lectin, one line cross-reacting with the Amaryllidaceae ...
Tópico(s): Biochemical and Structural Characterization
1991 - Elsevier BV | Phytochemistry
Aneta Liwosz, Tianlei Lei, Maria A. Kukuruzinska,
... Darby canine kidney; DSA, Datura stramonium agglutinin; GNA, Galanthus nivalis agglutinin; SNA, Sambucus nigra agglutinin.2The abbreviations used ... Darby canine kidney; DSA, Datura stramonium agglutinin; GNA, Galanthus nivalis agglutinin; SNA, Sambucus nigra agglutinin. (4Jamora C. Fuchs ... incubated for 1 h with digoxigenin-labeled lectins Galanthus nivalis agglutinin (GNA), Sambucas nigra agglutinin (SNA), and Datura ...
Tópico(s): Wnt/β-catenin signaling in development and cancer
2006 - Elsevier BV | Journal of Biological Chemistry
Yann Guérardel, Emmanuel Maes, Elisabeth Elass, Y. Leroy, Philippe Timmerman, Gurdyal S. Besra, Camille Locht, Gérard Strecker, Laurent Kremer,
... motif, which reacted specifically with the lectin from Galanthus nivalis, was found to be unique among a panel ... motif, which reacted specifically with the lectin from Galanthus nivalis, was found to be unique among a panel ... impact gas chromatography/mass spectrometry glycerol lectin from Galanthus nivalis Heteronuclear multiple bound correlation heteronuclear multiple quantum coherence ...
Tópico(s): Tuberculosis Research and Epidemiology
2002 - Elsevier BV | Journal of Biological Chemistry
... Carbohydrates of the foliage Leaf of the Snowdrop (Galanthus nivalis, L.), and their bearing on the first Sugar ... Carbohydrates of the foliage Leaf of the Snowdrop (Galanthus nivalis, L.), and their bearing on the first Sugar ...
Tópico(s): Plant nutrient uptake and metabolism
1912 - Portland Press | Biochemical Journal
Strahil Berkov, Jaume Bastida, Boriana Sidjimova, Françesc Viladomat, Carles Codina,
The alkaloid patterns of two occasionally sympatric Galanthus nivalis and Galanthus elwesii populations were studied by GC/MS. Thirty-seven alkaloids were detected, 25 for G. nivalis and 17 for G. elwesii. ... to occur in both species. The populations of Galanthus differed in their alkaloid biosynthetic pathways. Thus, the alkaloid pattern of G. nivalis was dominated by compounds coming from a para– ...
Tópico(s): Psychedelics and Drug Studies
2008 - Elsevier BV | Biochemical Systematics and Ecology
İbrahim Bulduk, Yasemin Karafakıoglu,
... and antioxidant activities in Galanthus species (Gaalanthus woronowii, Galanthus nivalis, and Galanthus elwesii) indigenous to Turkey. Study Design: ... Galanthus elwesii samples were collected in Antalya province, Galanthus nivalis samples were collected in Istanbul province, and Galanthus woronowii samples were collected in Çaykara, Trabzon province ...
Tópico(s): Alkaloids: synthesis and pharmacology
2019 - Sciencedomain International | International Journal of Biochemistry Research & Review
Rosângela P. da Silva, Siamon GORDON,
... binding of agglutinins from peanut, Amaranthus caudatus and Galanthus nivalis, whereas binding of the sialic-acid-specific Maakia ... abolishes the incorporation of [3H]mannose label and Galanthus nivalis agglutinin binding activity, but preserves the incorporation of ...
Tópico(s): Cellular transport and secretion
1999 - Portland Press | Biochemical Journal
Rosângela P. da Silva, Siamon GORDON,
... binding of agglutinins from peanut, Amaranthus caudatus and Galanthus nivalis, whereas binding of the sialic-acid-specific Maakia ... abolishes the incorporation of [3H]mannose label and Galanthus nivalis agglutinin binding activity, but preserves the incorporation of ...
Tópico(s): Complement system in diseases
1999 - Portland Press | Biochemical Journal
... Effects of diets containing genetically modified potatoes expressing Galanthus nivalis lectin on rat small intestine..Lancet. 1999; 354: ... Scholar raise intriguing questions about the potential of Galanthus nivalis agglutinin (GNA) to cause morphological alterations in the ...
Tópico(s): Transgenic Plants and Applications
1999 - Elsevier BV | The Lancet
Akira Maeda, Takehisa Ueno, Shino Nakatsu, Dandan Wang, Noriaki Usui, Shunsaku Takeishi, Teru Okitsu, Masafumi Goto, Hiroshi Nagashima, Shuji Miyagawa,
... for Lotus tetragonolobus, Aleuria aurantia, Narcissus pseudonarcissus, and Galanthus nivalis, suggesting that APIs contain high levels of high- ... than the others in Lotus tetragonolobus, Narcissus pseudonarcissus, Galanthus nivalis, and Urtica dioica, implying the presence of high- ...
Tópico(s): Animal Genetics and Reproduction
2013 - Elsevier BV | Journal of Surgical Research
Strahil Berkov, Jaume Bastida, Boriana Sidjimova, Françesc Viladomat, Carles Codina,
... GC/MS in 25 Galanthus elwesii and seven Galanthus nivalis populations, collected from different locations in Bulgaria. Intraspecies ... galanthamine‐type alkaloids. The alkaloid profiles of G. nivalis were dominated by narciclasine‐, galanthamine‐, lycorine‐, haemanthamine‐, or tazettine‐type compounds. Geographical distribution of chemotypes indicated a relationship between populations, since adjacent populations often displayed similar alkaloid profiles. The results from year‐to‐year sampling and transplantation experiments imply genetic determination of alkaloid synthesis in the two studied species of Galanthus.
Tópico(s): Cholinesterase and Neurodegenerative Diseases
2011 - Wiley | Chemistry & Biodiversity
Pierre Sibille, A. Avrameas, A. Moraillon, Jennifer Richardson, P. Sonigo, G. Pancino, A.D. Strosberg,
... radio-immunoprecipitation assay. A sandwich-ELISA test using Galanthus nivalis agglutinin, a lectin that specifically binds terminal mannose ... to feline immunodeficiency virus, and moreover that the Galanthus nivalis ELISA could be useful in equivocal cases as ...
Tópico(s): Virology and Viral Diseases
1995 - Elsevier BV | Veterinary Microbiology
Daniela Benedec, Ilioara Oniga, Daniela Hanganu, Ana Maria Gheldiu, Cristina Puşcaş, Radu Silaghi‐Dumitrescu, Mihaela Duma, Brînduşa Tiperciuc, Rodica Vârban, Laurian Vlase,
Although Galanthus nivalis L. (snowdrop) is known for the galanthamine content, used in the treatment of Alzheimer disease, the polyphenolic ... of four selected Amaryllidaceae species harvested from Romania (Galanthus nivalis L., Narcissus pseudonarcissus L., N. poeticus L. and Leucojum vernum L.) was determined by spectrophotometric methods; the ...
Tópico(s): Botanical Research and Applications
2018 - BioMed Central | BMC Complementary and Alternative Medicine
Nur Afiqah Sukiran, Prashant Pyati, Caitlin E. Willis, Adrian P. Brown, Jennifer J. Readshaw, Elaine Fitches,
... whether fusion of the peptide to snowdrop lectin, (Galanthus nivalis agglutinin; GNA) enhances the efficacy of this venom ...
Tópico(s): Entomopathogenic Microorganisms in Pest Control
2022 - Wiley | Pest Management Science
Zarel Martinez, Kristof De Schutter, Els J. M. Van Damme, Elise Vogel, Niels Wynant, Jozef Vanden Broeck, Olivier Christiaens, Guy Smagghe,
... evaluated. First, a fusion protein consisting of the Galanthus nivalis agglutinin (GNA) and a dsRNA binding domain was ...
Tópico(s): CRISPR and Genetic Engineering
2021 - Elsevier BV | Pesticide Biochemistry and Physiology
Kritsada Pruksaphon, Akarin Intaramat, Pavinee Simsiriwong, Skorn Mongkolsuk, Kavi Ratanabanangkoon, Joshua D. Nosanchuk, Anna Kaltsas, Sirida Youngchim,
... nanoparticle was used as a specific signal reporter. Galanthus nivalis Agglutinin (GNA) was adsorbed onto nitrocellulose membrane to ...
Tópico(s): Antifungal resistance and susceptibility
2021 - Public Library of Science | PLoS neglected tropical diseases
Majid Rahimi Khonakdari, Mohammad Hossein Mirjalili, Abbas Gholipour, Hassan Rezadoost, Mahdi Moridi Farimani,
... In the present study, a total of six Galanthus nivalis populations (GNPs) and 11 Narcissus tazetta populations (NTPs) ...
Tópico(s): Psychedelics and Drug Studies
2017 - Cambridge University Press | Plant Genetic Resources
Xiaoxiao Mi, Xue Liu, Haolu Yan, Lina Liang, Xiangyan Zhou, Jiangwei Yang, Huaijun Si, Ning Zhang,
... health. In this study, transgenic potato plants expressing Galanthus nivalis agglutinin (GNA) gene were developed using CaMV 35S ...
Tópico(s): Insect-Plant Interactions and Control
2016 - Elsevier BV | Comptes Rendus Biologies
Elżbieta Weryszko‐Chmielewska, Mirosława Chwil,
In Poland <em>Galanthus nivalis</em> L. is partially protected. The flowers of this species are one of the first sources of nectar and ...
Tópico(s): Plant Parasitism and Resistance
2016 - Polish Botanical Society | Acta Societatis Botanicorum Poloniae
Saber Delpasand Khabbazi, Allah Bakhsh, Cengiz Sancak, Sebahattin Özcan,
... plant lectin gene GNA. The lectin, present in Galanthus nivalis (snowdrop), is an agglutinin toxic to hemiptera. The ... National Centrer for Biotechnology Information database), trGNA from Galanthus nivalis is most similar to the previously reported lectin ...
Tópico(s): Plant and animal studies
2016 - Czech Academy of Agricultural Sciences | Czech Journal of Genetics and Plant Breeding
Bodan Hu, Tao Du, Chang Li, Sukun Luo, Yalan Liu, Xin Huang, Qinxue Hu,
... CBAs) griffithsin (GRFT), cyanovirin-N (CV-N) and Galanthus nivalis agglutinin (GNA), showing that T/F Envs demonstrated ...
Tópico(s): Transgenic Plants and Applications
2015 - Microbiology Society | Journal of General Virology
Rosemary J. Newton, Fiona R. Hay, R. H. Ellis,
... in the winter-flowering, moist temperate woodland species Galanthus nivalis and Narcissus pseudonarcissus are complex and poorly understood. ...
Tópico(s): Botanical Research and Applications
2015 - Oxford University Press | Botanical Journal of the Linnean Society
Rosemary J. Newton, Fiona R. Hay, R. H. Ellis,
Seeds of the moist temperate woodland species Galanthus nivalis and Narcissus pseudonarcissus, dispersed during spring or early summer, germinated poorly in laboratory tests. Seed development and maturation were studied to better understand ...
Tópico(s): Plant tissue culture and regeneration
2013 - Oxford University Press | Annals of Botany
Elżbieta Weryszko‐Chmielewska, Mirosława Chwil,
The structure of the flowers of <i>Galanthus nivalis</i> shows adaptations to early spring flowering conditions as well as adaptations to entomogamy. The tepals produce colour marks and odorous substances. The ...
Tópico(s): Plant Diversity and Evolution
2012 - Polish Botanical Society | Acta Agrobotanica
Simon Blank, C. Richard Neu, Daniel Hasche, Frank I. Bantleon, Thilo Jakob, Edzard Spillner,
... reactivity of European and American PV. We utilized Galanthus nivalis agglutinin, which indicates the general presence of N- ... Scopus (141) Google Scholar of insect venoms. Applying Galanthus nivalis agglutinin in AlaBlots (Siemens Healthcare Diagnostics, Los Angeles, ...
Tópico(s): Viral Infectious Diseases and Gene Expression in Insects
2012 - Elsevier BV | Journal of Allergy and Clinical Immunology
Bart Hoorelbeke, Els J. M. Van Damme, Pierre Rougé, Dominique Schols, Kristel Van Laethem, Elke Fouquaert, Jan Balzarini,
... the carbohydrate-binding specificities of the plant lectins Galanthus nivalis (GNA) and the closely related lectin from Zea ...
Tópico(s): Transgenic Plants and Applications
2011 - BioMed Central | Retrovirology