Árpád Pusztai, J.F.J.G. Koninkx, Henno Hendriks, Wouter Kok, Saskia Hulscher, Els J. M. Van Damme, Willy J. Peumans, George Grant, Susan Bardócz,
... assess whether the presently most favored insecticidal lectin, Galanthus nivalis agglutinin, would be harmful for mammals. Effects of Galanthus nivalis agglutinin on gut and brush border enzymes were ... did not reduce the growth of young rats, Galanthus nivalis agglutinin had negligible effects on the weight and ... in gut metabolism caused by the incorporation of Galanthus nivalis agglutinin in the diet were less extensive than ... to establish whether it is safe to use Galanthus nivalis agglutinin in transgenic plants destined for human consumption.
Tópico(s): Plant tissue culture and regeneration
1996 - Elsevier BV | The Journal of Nutritional Biochemistry
Florian Tribl, Manfred Gerlach, Katrin Marcus, Esther Asan, Thomas Tatschner, Thomas Arzberger, Helmut E. Meyer, Gerhard Bringmann, Peter Riederer,
... one-dimensional; LAMP, lysosome-associated membrane glycoprotein; GNA, Galanthus nivalis agglutinin; LIMP, lysosome membrane protein; ER, endoplasmic reticulum; ... one-dimensional; LAMP, lysosome-associated membrane glycoprotein; GNA, Galanthus nivalis agglutinin; LIMP, lysosome membrane protein; ER, endoplasmic reticulum; ... and cathepsin B were purchased from Calbiochem. Biotinylated Galanthus nivalis agglutinin (GNA) and horseradish peroxidase-linked streptavidin were ... of a mannose-specific lectin from the snowdrop (Galanthus nivalis) bulb.J. Biol. Chem. 1988; 263: 728-734Google ...
Tópico(s): Connexins and lens biology
2005 - Elsevier BV | Molecular & Cellular Proteomics
Keiko Fukushima, Katsuko Yamashita,
... IL-2 receptor α subunit was stained with Galanthus nivalis agglutinin which specifically recognizes high-mannose type glycans. ... IL-2 receptor α subunit was stained with Galanthus nivalis agglutinin which specifically recognizes high-mannose type glycans. ... N-acetylglucosaminidase H endo-β-N-acetylglucosaminidase D Galanthus nivalis agglutinin recombinant human interleukin-2 polyacrylamide gel electrophoresis ... only the IL-2Rα subunit was stained with Galanthus nivalis agglutinin (GNA) which specifically recognizes high-mannose type ...
Tópico(s): Fungal Infections and Studies
2001 - Elsevier BV | Journal of Biological Chemistry
... Effect of diets containing genetically modified potatoes expressing Galanthus nivalis lectin on rat small intestineDiets containing genetically modified (GM) potatoes expressing the lectin Galanthus nivalis agglutinin (GNA) had variable effects on different parts ... potential risks to human health of the lectin Galanthus nivalis agglutinin (GNA), a compound that may be useful ...
Tópico(s): Nutrition, Genetics, and Disease
1999 - Elsevier BV | The Lancet
Els J. M. Van Damme, Irwin Goldstein, Willy J. Peumans,
... Narcissus pseudonarcissus and Clivia miniata) or tetramers (in Galanthus nivalis, Hippeastrum hybrid, Allium cepa and A. porrum. Most ... Alliaceae bulbs. Antisera raised in rabbits against the Galanthus nivalis and the Narcissus cv Carlton lectins gave, upon ... same assay was carried out with antiserum against Galanthus nivalis lectin, one line cross-reacting with the Amaryllidaceae ...
Tópico(s): Biochemical and Structural Characterization
1991 - Elsevier BV | Phytochemistry
Aneta Liwosz, Tianlei Lei, Maria A. Kukuruzinska,
... Darby canine kidney; DSA, Datura stramonium agglutinin; GNA, Galanthus nivalis agglutinin; SNA, Sambucus nigra agglutinin.2The abbreviations used ... Darby canine kidney; DSA, Datura stramonium agglutinin; GNA, Galanthus nivalis agglutinin; SNA, Sambucus nigra agglutinin. (4Jamora C. Fuchs ... incubated for 1 h with digoxigenin-labeled lectins Galanthus nivalis agglutinin (GNA), Sambucas nigra agglutinin (SNA), and Datura ...
Tópico(s): Wnt/β-catenin signaling in development and cancer
2006 - Elsevier BV | Journal of Biological Chemistry
... Carbohydrates of the foliage Leaf of the Snowdrop (Galanthus nivalis, L.), and their bearing on the first Sugar ... Carbohydrates of the foliage Leaf of the Snowdrop (Galanthus nivalis, L.), and their bearing on the first Sugar ...
Tópico(s): Plant nutrient uptake and metabolism
1912 - Portland Press | Biochemical Journal
Yann Guérardel, Emmanuel Maes, Elisabeth Elass, Y. Leroy, Philippe Timmerman, Gurdyal S. Besra, Camille Locht, Gérard Strecker, Laurent Kremer,
... motif, which reacted specifically with the lectin from Galanthus nivalis, was found to be unique among a panel ... motif, which reacted specifically with the lectin from Galanthus nivalis, was found to be unique among a panel ... impact gas chromatography/mass spectrometry glycerol lectin from Galanthus nivalis Heteronuclear multiple bound correlation heteronuclear multiple quantum coherence ...
Tópico(s): Tuberculosis Research and Epidemiology
2002 - Elsevier BV | Journal of Biological Chemistry
Strahil Berkov, Jaume Bastida, Boriana Sidjimova, Françesc Viladomat, Carles Codina,
The alkaloid patterns of two occasionally sympatric Galanthus nivalis and Galanthus elwesii populations were studied by GC/MS. Thirty-seven alkaloids were detected, 25 for G. nivalis and 17 for G. elwesii. ... to occur in both species. The populations of Galanthus differed in their alkaloid biosynthetic pathways. Thus, the alkaloid pattern of G. nivalis was dominated by compounds coming from a para– ...
Tópico(s): Psychedelics and Drug Studies
2008 - Elsevier BV | Biochemical Systematics and Ecology
İbrahim Bulduk, Yasemin Karafakıoglu,
... and antioxidant activities in Galanthus species (Gaalanthus woronowii, Galanthus nivalis, and Galanthus elwesii) indigenous to Turkey. Study Design: ... Galanthus elwesii samples were collected in Antalya province, Galanthus nivalis samples were collected in Istanbul province, and Galanthus woronowii samples were collected in Çaykara, Trabzon province ...
Tópico(s): Alkaloids: synthesis and pharmacology
2019 - Sciencedomain International | International Journal of Biochemistry Research & Review
Rosângela P. da Silva, Siamon GORDON,
... binding of agglutinins from peanut, Amaranthus caudatus and Galanthus nivalis, whereas binding of the sialic-acid-specific Maakia ... abolishes the incorporation of [3H]mannose label and Galanthus nivalis agglutinin binding activity, but preserves the incorporation of ...
Tópico(s): Complement system in diseases
1999 - Portland Press | Biochemical Journal
Rosângela P. da Silva, Siamon GORDON,
... binding of agglutinins from peanut, Amaranthus caudatus and Galanthus nivalis, whereas binding of the sialic-acid-specific Maakia ... abolishes the incorporation of [3H]mannose label and Galanthus nivalis agglutinin binding activity, but preserves the incorporation of ...
Tópico(s): Cellular transport and secretion
1999 - Portland Press | Biochemical Journal
... Effects of diets containing genetically modified potatoes expressing Galanthus nivalis lectin on rat small intestine..Lancet. 1999; 354: ... Scholar raise intriguing questions about the potential of Galanthus nivalis agglutinin (GNA) to cause morphological alterations in the ...
Tópico(s): Transgenic Plants and Applications
1999 - Elsevier BV | The Lancet
Akira Maeda, Takehisa Ueno, Shino Nakatsu, Dandan Wang, Noriaki Usui, Shunsaku Takeishi, Teru Okitsu, Masafumi Goto, Hiroshi Nagashima, Shuji Miyagawa,
... for Lotus tetragonolobus, Aleuria aurantia, Narcissus pseudonarcissus, and Galanthus nivalis, suggesting that APIs contain high levels of high- ... than the others in Lotus tetragonolobus, Narcissus pseudonarcissus, Galanthus nivalis, and Urtica dioica, implying the presence of high- ...
Tópico(s): Animal Genetics and Reproduction
2013 - Elsevier BV | Journal of Surgical Research
Strahil Berkov, Jaume Bastida, Boriana Sidjimova, Françesc Viladomat, Carles Codina,
... GC/MS in 25 Galanthus elwesii and seven Galanthus nivalis populations, collected from different locations in Bulgaria. Intraspecies ... galanthamine‐type alkaloids. The alkaloid profiles of G. nivalis were dominated by narciclasine‐, galanthamine‐, lycorine‐, haemanthamine‐, or tazettine‐type compounds. Geographical distribution of chemotypes indicated a relationship between populations, since adjacent populations often displayed similar alkaloid profiles. The results from year‐to‐year sampling and transplantation experiments imply genetic determination of alkaloid synthesis in the two studied species of Galanthus.
Tópico(s): Cholinesterase and Neurodegenerative Diseases
2011 - Wiley | Chemistry & Biodiversity
Pierre Sibille, A. Avrameas, A. Moraillon, Jennifer Richardson, P. Sonigo, G. Pancino, A.D. Strosberg,
... radio-immunoprecipitation assay. A sandwich-ELISA test using Galanthus nivalis agglutinin, a lectin that specifically binds terminal mannose ... to feline immunodeficiency virus, and moreover that the Galanthus nivalis ELISA could be useful in equivocal cases as ...
Tópico(s): Virology and Viral Diseases
1995 - Elsevier BV | Veterinary Microbiology
Daniela Benedec, Ilioara Oniga, Daniela Hanganu, Ana Maria Gheldiu, Cristina Pușcaș, Radu Silaghi‐Dumitrescu, Mihaela Duma, Brînduşa Tiperciuc, Rodica Vârban, Laurian Vlase,
Although Galanthus nivalis L. (snowdrop) is known for the galanthamine content, used in the treatment of Alzheimer disease, the polyphenolic ... of four selected Amaryllidaceae species harvested from Romania (Galanthus nivalis L., Narcissus pseudonarcissus L., N. poeticus L. and Leucojum vernum L.) was determined by spectrophotometric methods; the ...
Tópico(s): Botanical Research and Applications
2018 - BioMed Central | BMC Complementary and Alternative Medicine
Abstract Aus Zwiebeln von Galanthus nivalis werden Tazettin und Spuren von Lycorin isoliert.
Tópico(s): Botanical Research and Chemistry
1954 - Wiley | Chemische Berichte
... Issue 4 p. 344-356 XVI.—MITOSIS IN GALANTHUS NIVALIS* With special reference to chromosome structure, and the ...
Tópico(s): Lichen and fungal ecology
1932 - Royal Microscopical Society | Journal of the Royal Microscopical Society
Andreas Plaitakis, Roger C. Duvoisin,
... hypothesis that “moly” might have been the snowdrop, Galanthus nivalis, which contains galanthamine, a centrally acting anticholinesterase. Thus ...
Tópico(s): Cholinesterase and Neurodegenerative Diseases
1983 - Lippincott Williams & Wilkins | Clinical Neuropharmacology
Catherine Wright, Hanae Kaku, Irwin Goldstein,
... grown for a mannose-specific lectin from snowdrop (Galanthus nivalis) bulbs in the presence of methyl-alpha-D- ...
Tópico(s): Hemoglobin structure and function
1990 - Elsevier BV | Journal of Biological Chemistry
Els J. M. Van Damme, Anthony K. Allen, Willy J. Peumans,
A lectin was isolated from snowdrop ( Galanthus nivalis ) bulbs by affinity chromatography on mannoseagarose. It is a tetrameric protein composed of 4 identical subunits of 13 kDa which are not ...
Tópico(s): Polysaccharides and Plant Cell Walls
1987 - Wiley | FEBS Letters
Els J. M. Van Damme, Willy J. Peumans,
The biosynthesis and processing of the Galanthus nivalis agglutinin were studied in vivo in ripening snowdrop ovaries. Using labeling and pulse chase labeling experiments it could be demonstrated that the ...
Tópico(s): Phytochemical compounds biological activities
1988 - Oxford University Press | PLANT PHYSIOLOGY
Bo Liu, Bo Zhang, Mingwei Min, He-jiao Bian, Longfei Chen, Qian Liu, Jinku Bao,
The Galanthus nivalis agglutinin (GNA)-related lectins have been reported to bear antiproliferative and apoptosis-inducing activities in cancer cells; ... for further understanding cell death mechanisms of the Galanthus nivalis agglutinin (GNA)-related lectins in future cancer investigations.
Tópico(s): Phytochemical Studies and Bioactivities
2009 - Elsevier BV | Biochimica et Biophysica Acta (BBA) - General Subjects
Chunyang Li, Meng Liang, Bo Liu, Jinku Bao,
Galanthus nivalis agglutinin (GNA)-related lectin family, a superfamily of strictly mannose-binding specific lectins widespread among monotyledonous ...
Tópico(s): Chemical Synthesis and Analysis
2009 - Bentham Science Publishers | Current Chemical Biology
Piotr Trębicki, R. M. Harding, K.S. Powell,
... 1 p. 99-105 Anti-metabolic effects of Galanthus nivalis agglutinin and wheat germ agglutinin on nymphal stages ...
Tópico(s): Insect Pest Control Strategies
2009 - Wiley | Entomologia Experimentalis et Applicata
Els J. M. Van Damme, Hanae Kaku, Fulvio Perini, Irwin Goldstein, Ben Peeters, Fumio Yagi, B. Decock, Willy J. Peumans,
... rich RNA isolated from ripening ovaries of snowdrop ( Galanthus nivalis L.) yielded a single 17‐kDa lectin polypeptide ...
Tópico(s): Glycosylation and Glycoproteins Research
1991 - Wiley | European Journal of Biochemistry
... receptor digoxigenin neuraminidase horseradish peroxidase Vicia villosa agglutinin Galanthus nivalis agglutinin Datura stramonium agglutinin peanut agglutinin Maackia amurensis ... MuSK (Fig. 1 A). Other lectins, such as Galanthus nivalis agglutinin (GNA), which recognizes high-mannose structures inN- ...
Tópico(s): Muscle Physiology and Disorders
2002 - Elsevier BV | Journal of Biological Chemistry
Mamoudou Sétamou, Julio S. Bernal, Jesusa C. Legaspi, T. Erik Mirkov,
Journal Article Effects of Snowdrop Lectin (Galanthus nivalis Agglutinin) Expressed in Transgenic Sugarcane on Fitness of Cotesia flavipes (Hymenoptera: Braconidae), a Parasitoid of the Nontarget Pest Diatraea saccharalis (Lepidoptera: Crambidae) ...
Tópico(s): Insect Pest Control Strategies
2002 - Oxford University Press | Annals of the Entomological Society of America
Christophe Ripoll, Bruno Favery, Philippe Lecomte, Els J. M. Van Damme, Willy J. Peumans, Pierre Abad, Lise Jouanin,
... expressing the mannose binding lectin GNA from snowdrop (Galanthus nivalis), under the control of the constitutive 35S promoter ...
Tópico(s): Plant tissue culture and regeneration
2003 - Elsevier BV | Plant Science