Sara Varela Amaral, Teresa Forte, João Ramalho‐Santos, M. Teresa Girão da Cruz,
Although science and technology impact every aspect of modern societies, there is still an extensive gap between science and society, which impairs the full exercise of citizenship. In the particular case of biomedical research increased investment should be accompanied by parallel efforts in terms of public information and engagement. We have carried out a project involving the production and evaluation of educational contents focused on stem cells - illustrated newspaper chronicles, radio interviews, ...
Tópico(s): Science, Research, and Medicine
2015 - Public Library of Science | PLoS ONE
Gildàsio S. De Oliveira, Walter Girao, Paul C. Fitzgerald, Robert J. McCarthy,
To compare the incidence of upper airway morbidity with sevoflurane versus desflurane in patients undergoing general anesthesia with a Laryngeal Mask Airway (LMA). Systematic review and meta-analysis of randomized controlled trials (RCTs). Operating room of an academic medical center. A systematic review of RCTs of patients receiving general anesthesia with a LMA was performed. Sevoflurane and desflurane were used for maintenance of anesthesia in the RCTs. A wide search was performed to identify RCTs ...
Tópico(s): Respiratory Support and Mechanisms
2013 - Elsevier BV | Journal of Clinical Anesthesia

Levi Lopes de Lima, Frederico Girão,
We establish versions of the positive mass and Penrose inequalities for a class of asymptotically hyperbolic hypersurfaces. In particular, under the usual dominant energy condition, we prove in all dimensions $$n\ge 3$$ an optimal Penrose inequality for certain graphs in hyperbolic space $$\mathbb {H}^{n+1}$$ whose boundary has constant mean curvature $$n-1$$ . This settles, for this class of manifolds, an inequality first conjectured by Wang (J Differ Geom 57(2):273–299, 2001).
Tópico(s): Geometry and complex manifolds
2015 - Springer Science+Business Media | General Relativity and Gravitation

Luís Fernando Aranha Camargo, Alexandre R. Marra, Antônio Carlos Campos Pignatari, Teresa Sukiennik, P.P.P. Behar, Eduardo Alexandrino Medeiros, Julival Ribeiro, Evelyne Santana Girão, Luci Corrêa, Carla Morales Guerra, Carlos Brites, Carlos Alberto Pereira, Irna Carla do Rosário Souza Carneiro, Marise Auxiliadora de Barros Reis, Marta Antunes de Souza, Cristina U. Barata, Michael B. Edmond,
Abstract Background The incidence of bloodstream infection ( BSI ) varies according to the transplanted organ. Mortality can be as high as 24%, with a significant impact on graft survival. Transplantation is a risk factor for multidrug‐resistant ( MDR ) organisms, but comparison with a non‐transplanted population in a single large cohort has not been described. Methods This is a prospective nationwide study (16 centers) reporting data on 2364 monomicrobial nosocomial BSI s, comparing 83 episodes in solid ...
Tópico(s): Mycobacterium research and diagnosis
2015 - Wiley | Transplant Infectious Disease
Jorge M. Alves-Silva, Mónica Zuzarte, Henrique Girão, Lı́gia Salgueiro,
... or by acting on related targets, or exerting general cellular protection. In general, monoterpenic compounds are the most studied regarding hypotensive ...
Tópico(s): Pharmacological Effects of Natural Compounds
2021 - Multidisciplinary Digital Publishing Institute | Molecules

Paula Cotrin, Amelia Cristine Bahls, Daniella de Oliveira da Silva, Valquiria Mendes Pereira Girão, Célia Regina Maio Pinzan‐Vercelino, Ricardo César Gobbi de Oliveira, Renata Cristina Gobbi de Oliveira, Maria Dalva de Barros Carvalho, Sandra Marisa Pelloso, Fabrício Pinelli Valarelli, Karina Maria Salvatore de Freitas,
... reducing the spread of the virus when the general population's compliance is high. Some factors that ...
Tópico(s): Body Image and Dysmorphia Studies
2020 - Dove Medical Press | Journal of Multidisciplinary Healthcare

Vanessa Apfel, Cláudia Cristina Takano, Gisele Vissoci Marquini, Zsuzsanna Ilona Katalin de Jármy Di Bella, Manoel Joâo Batista Castello Girão, Marair Grácio Ferreira Sartori,
... a follow‐up including medical history, physical examination, general satisfaction, clinical aspect of the vagina, Female Sexual ...
Tópico(s): Gynecological conditions and treatments
2021 - Elsevier BV | International Journal of Gynecology & Obstetrics

Paulo D’Amora, Thiago Trovati Maciel, Rodrigo Tambellini, Marcelo A. Mori, João Bosco Pesquero, Hélio Sato, Manoel Joâo Batista Castello Girão, Ismael Dale Cotrim Guerreiro da Silva, Eduardo Schor,
... proliferation9Schor E Silva IDCG Sato H Baracat EC Girão MJBC Freitas V P27Kip1 is down-regulated in ... da Silva ID Baracat EC de Lima GR Girao MJ The progesterone receptor gene polymorphism. PROGINS, may ... De-Souza NC Massad-Costa AM Baracat EC Girão MJBC D'Amora P Schor E Silva IDCG ... De-Souza NC Massad-Costa AM Baracat EC Girão MJBC D'Amora P Schor E Silva IDCG ...
Tópico(s): Uterine Myomas and Treatments
2009 - Elsevier BV | American Journal Of Pathology

José Huygens Parente Garcia, Tarciso Daniel Santos Rocha, Cyntia Ferreira Gomes Viana, Bronner P. Gonçalves, Evelyne Santana Girão, J.B.M. Vasconcelos, Gustavo Coelho, Dirk Schreen, Paulo Everton Garcia Costa, Ivelise Regina Canito Brasil,
... G. Viana Bronner P.A. Gonçalves Evelyne S. Girão João B.M. Vasconcelos Gustavo R. Coelho Dirk ...
Tópico(s): Malaria Research and Control
2006 - Wolters Kluwer | Transplantation

Michael Hortsch, Nii Koney‐Kwaku Koney, Aswathy Maria Oommen, Doris George Yohannan, Yan Li, Ana Caroline Rocha de Melo Leite, Virgínia Cláudia Carneiro Girão‐Carmona,
... as developing areas of the globe. We identify general and local roadblocks to the introduction of this ...
Tópico(s): Genetics, Bioinformatics, and Biomedical Research
2023 - Springer Nature | Advances in experimental medicine and biology
Alyne Lamy-Mendes, Rafael B. Torres, João P. Vareda, David Lopes, Marco Ferreira, Vanessa Valente, Ana V. Girão, Artur J. M. Valente, Luísa Durães,
Serious environmental and health problems arise from the everyday release of industrial wastewater effluents. A wide range of pollutants, such as volatile organic compounds, heavy metals or textile dyes, may be efficiently removed by silica materials advanced solutions such as aerogels. This option is related to their exceptional characteristics that favors the adsorption of different contaminants. The aerogels performance can be selectively tuned by an appropriate chemical or physical modification ...
Tópico(s): Mesoporous Materials and Catalysis
2019 - Multidisciplinary Digital Publishing Institute | Molecules
Naomi A. Carne, Steven Bell, Adrian P. Brown, Arto Määttå, Michael J. Flagler, Adam M. Benham,
... T. Anjo S.I. Pereira P. Manadas B. Girao H. Interacting network of the gap junction (GJ) ...
Tópico(s): melanin and skin pigmentation
2019 - Elsevier BV | Molecular & Cellular Proteomics
Gerbrand A. Zoet, Laura Benschop, Eric Boersma, Ricardo P.J. Budde, Bart C.J.M. Fauser, Yolanda van der Graaf, Christianne J.M. de Groot, Angela H.E.M. Maas, Jeanine E. Roeters van Lennep, Eric A.P. Steegers, Frank L.J. Visseren, Bas B. van Rijn, Birgitta K. Velthuis, Arie Franx, Yolande E. Appelman, Sara J. Baart, Laura Brouwers, Suzanne C. Cannegieter, Veerle Dam, Marianne Eijkemans, Michel D. Ferrari, Marlise N. Gunning, Annemieke Hoek, Hendrik Koffijberg, Maria P.H. Koster, Mark C. Kruit, Giske R. Lagerwij, Cornelis B. Lambalk, Joop S.E. Laven, Katie M. Linstra, Aad van der Lugt, Antoinette MaassenVanDenBrink, Cindy Meun, Saskia Middeldorp, Karel G.M. Moons, Jolien W. Roos‐Hesselink, Luuk J.J. Scheres, Régine P.M. Steegers‐Theunissen, Gisela M. Terwindt, Marieke J.H. Wermer,
... S, den Ruijter H, Engel F, Gerdts E, Girao H, Gyöngyösi M, Hausenloy D, Lecour S, Madonna ...
Tópico(s): Cardiovascular Health and Disease Prevention
2018 - Lippincott Williams & Wilkins | Circulation
Gerd Heusch, Andreas Skyschally, Petra Kleinbongard,
... I, Ferdinandy P, Galatou E, Garcia-Sosa A, Girao H, Giricz Z, Gyongyosi M, Hausenloy D, Healy ...
Tópico(s): Cardiac electrophysiology and arrhythmias
2018 - Lippincott Williams & Wilkins | Circulation Research

Luciana Oliveira Bruno, Ricardo Santos Simões, Manuel de Jesus Simões, Manoel Joâo Batista Castello Girão, Oliver Grundmann,
The indiscriminate use of herbal medicines to prevent or to heal diseases or even the use for questionable purposes such as weight loss has received both interest and scrutiny from the scientific community and general public alike. An increasing number of women put their own and the unborn child's health at risk due to a lack of knowledge about the phytochemical properties and adequate use of herbal medicine (phytomedicines or herbal supplements) and lack of communication with their healthcare provider. ...
Tópico(s): Pregnancy and Medication Impact
2018 - Wiley | Phytotherapy Research

P.F.C.B.C. Fernandes, Reed André Siqueira, Evelyne Santana Girão, Rainne André Siqueira, Márcia Uchoa Mota, Leyla Castelo Branco Fernandes Marques, Silvana Cristina Albuquerque Andrade, Wilson Mendes Barroso, Sônia Leite Silva, Bruno Gomes Rodrigues dos Santos, Cláudia Maria Costa de Oliveira,
To present clinical characteristics from renal transplant recipients with dengue fever and its impact on graft function.We retrospectively evaluated 11 renal transplant recipients (RTR) with dengue infection confirmed by laboratory test, between January 2007 and July 2012, transplanted in the Renal Transplant Center of Walter Cantídio University Hospital from Federal University of Ceará.Positive dengue serology (IgM) was found in all patients. The mean time between transplant and dengue infection ...
Tópico(s): Malaria Research and Control
2017 - Baishideng Publishing Group | World Journal of Transplantation

Evelyne Santana Girão, Bruno Gomes Rodrigues dos Santos, E.S. do Amaral, Paulo Everton Garcia Costa, Karla Brandão Pereira, Antônio Haroldo de Araújo Filho, Elodie Bomfim Hyppólito, Márcia Uchoa Mota, Leyla Castelo Branco Fernandes Marques, Cláudia Maria Costa de Oliveira, S.L. da Silva, José Huygens Parente Garcia, P.F.C.B.C. Fernandes,
Chikungunya virus (CHIKV) is an emerging mosquito-borne disease that causes acute febrile polyarthralgia and arthritis. CHIKV has spread rapidly to the Americas and, in Brazil, autochthonous cases are increasingly been reported. Solid organ transplant (SOT) recipients who travel to or live in CHIKV endemic areas are under high risk of acquiring the disease. Few data exist regarding the clinical characteristics of CHIKV infections in this population. We report the first case series of CHIKV infection ...
Tópico(s): Viral Infections and Vectors
2017 - Elsevier BV | Transplantation Proceedings

Maíta Poli de Araújo, Marair Grácio Ferreira Sartori, Manoel Joâo Batista Castello Girão,
In 1896, Baron Pierre de Coubertin inaugurated the first modern era Olympic Games. At that time, women could not participate in the competitions, as sports in general were considered dangerous for women's health. At the Paris Olympics (1900), of the 997 enrolled athletes, 22 were women who competed in sailing, tennis and golf.[1] Women's participation increased considerably, and in the 2016 Olympic Games, which were held in the city of Rio de Janeiro, almost half of the athletes were women.[2]
Tópico(s): Male Reproductive Health Studies
2017 - Thieme Medical Publishers (Germany) | Revista Brasileira Ginecologia e Obstetrícia
Sandra Cruz, André F. Girão, Gil Gonçalves, Paula A. A. P. Marques,
This paper reviews recent advances in graphene-based biosensors development in order to obtain smaller and more portable devices with better performance for earlier cancer detection. In fact, the potential of Graphene for sensitive detection and chemical/biological free-label applications results from its exceptional physicochemical properties such as high electrical and thermal conductivity, aspect-ratio, optical transparency and remarkable mechanical and chemical stability. Herein we start by ...
Tópico(s): Carbon and Quantum Dots Applications
2016 - Multidisciplinary Digital Publishing Institute | Sensors
Xavier Rosselló, Derek M. Yellon,
... Batista-Almeida D, Van Campenhout R, Vinken M, Girao H and Kwak B (2020) Canonical and Non- ...
Tópico(s): Acute Myocardial Infarction Research
2016 - Lippincott Williams & Wilkins | Circulation
Ana M. Girão Coelho, J. Toby Mottram, Kent A. Harries,
The results of a three-dimensional finite element study of the net section dominated failure behaviour of pultruded open-hole specimens are presented. Computer models are developed using the general-purpose software Abaqus. Several issues are addressed in the study with respect to the notched plate geometry: (i) thickness of plate, (ii) transverse centre-to-centre spacing of holes (gauge), and (iii) distance from the centre of the hole to the nearest edge. The analytical results provide information ...
Tópico(s): Structural Behavior of Reinforced Concrete
2015 - Elsevier BV | Composite Structures
João L. Costa, Pedro M. Girão, José Natário, Jorge Drumond Silva,
This paper is the second part of a trilogy dedicated to the following problem: given spherically symmetric characteristic initial data for the Einstein–Maxwell-scalar field system with a cosmological constant $${\Lambda}$$ , with the data on the outgoing initial null hypersurface given by a subextremal Reissner–Nordström black hole event horizon, study the future extendibility of the corresponding maximal globally hyperbolic development as a "suitably regular" Lorentzian manifold. In the first paper of ...
Tópico(s): Advanced Mathematical Physics Problems
2015 - Springer Science+Business Media | Communications in Mathematical Physics
Ana M. Girão Coelho, J. Toby Mottram, Kent A. Harries,
This paper presents a finite element modelling methodology to predict the initiation and damage progression in notched composite laminated plates subjected to increasing in-plane tension load. An important feature of the methodology is it does not rely on customized user-subroutines but solely on the analysis capabilities of the general purpose software Abaqus; thus ensuring that the numerical results can be universally reproduced. The methodology presented copes with intralaminar failure modes ...
Tópico(s): Structural Load-Bearing Analysis
2015 - Elsevier BV | Composite Structures
The focus of this paper is on the computational modelling of progressive damage in composite structures of fibre reinforced laminae. A general review of modelling approaches to failure in the context of the finite element method is first presented, with an emphasis on models based on continuum damage mechanics. The way in which delamination and matrix splitting (that may or may not interact with fibre-tension damage) should be addressed in the framework of a commercial finite element code is considered ...
Tópico(s): Structural Analysis and Optimization
2015 - Springer Science+Business Media | Archives of Computational Methods in Engineering

Joana Balça-Silva, Diana Matias, Anália do Carmo, Henrique Girão, Vivaldo Moura‐Neto, Ana Bela Sarmento‐Ribeiro, María Celeste Lopes,
Glioblastoma (GBM) is a highly proliferative, angiogenic grade IV astrocytoma that develops resistance to the alkylating agents used in chemotherapy, such as temozolomide (TMZ), which is considered the gold standard. The mean survival time for GBM patients is approximately 12 months, increasing to 14.6 months after TMZ treatment. The resistance of GBM to chemotherapy seems to be associated to genetic alterations and to the constitutive activation of several signaling pathways. Therefore, the combination ...
Tópico(s): Microtubule and mitosis dynamics
2014 - Elsevier BV | Biochimica et Biophysica Acta (BBA) - General Subjects

André Luiz Amarante Mesquita, Alexandre Luiz Amarante Mesquita, Felipe Coutinho Palheta, Jerson Rogério Pinheiro Vaz, Marcus Vinícius Girão de Morais, Carmo Gonçalves,
In recent years, increasing attention is being given to the study of hydrokinetic turbines for power generation due to the use of clean energy by using renewable sources. This paper aims to present a general methodology for the efficient design of horizontal axis hydrokinetic turbines with variable rotation. The approach uses the Blade Element Method (BEM) for determining the power coefficient of the turbine. The modeling of the hydrokinetic rotor is coupled with the model of the drive line of the ...
Tópico(s): Electric Motor Design and Analysis
2014 - Elsevier BV | Energy Conversion and Management

W.T. Clemente, E. Vidal, Evelyne Santana Girão, A.S.D. Ramos, F. Govedic, Esperanza Merino, Patricia Muñóz, Núria Sabé, Carlos Cervera, Gláucia Cota, Elisa Cordero, Álvaro Mena, Miguel Montejo, Francisco López‐Medrano, José María Aguado, Paula Frassinetti Castelo Branco Camurça Fernandes, Maricela Valerio, Jordi Carratalà, Asunción Moreno, João Antônio de Queiroz Oliveira, Paulo Henrique Orlandi Mourão, Julián Torre-Cisneros,
Visceral leishmaniasis (VL) is a rare disease in solid-organ transplant (SOT) recipients. Therefore, little is known about the risk factors and disease behavior in the transplant setting. This multicenter, matched case-control study (1:2 ratio) was designed to determine the risk factors, clinical features and outcomes of VL among this population. Control and case subjects were matched by center, transplant type and timing. Thirty-six VL cases were identified among 25 139 SOT recipients (0.1%). VL occurred ...
Tópico(s): Parasites and Host Interactions
2014 - Elsevier BV | Clinical Microbiology and Infection

José Tadeu Nunes Tamanini, Renata Cristina de Oliveira Souza Castro, Juliana Milhomem Tamanini, Paulo Cezar Feldner, Rodrigo Aquino Castro, Marair Grácio Ferreira Sartori, Manoel Joâo Batista Castello Girão,
Objective To compare the effects of two surgical procedures for the correction of anterior vaginal wall prolapse (AVWP) on the lower urinary tract symptoms (LUTS) using symptom questionnaires and quality of life (QoL). Materials and Methods One hundred women with Pelvic Organ Prolapse Quantification stage (POP-Q) ≥ 2 were randomly distributed in two preoperatory groups. The first group (mesh) (n = 45) received a polypropylene mesh (PM) implant and the control group (n = 55) was submitted to anterior colporraphy ...
Tópico(s): Anorectal Disease Treatments and Outcomes
2013 - Sociedade Brasileira de Urologia | International braz j urol

Antônio Thadeu Medeiros de Barros, T. M. Saueressig, Alberto Gomes, W. W. Koller, John Furlong, Eneide Santiago Girão, Alfredo da Cunha Pinheiro, F. de P. J. Alves-Branco, M. de F. M. Sapper, Ramayana Menezes Braga, Amaury Apolonio de Oliveira,
Since horn fly populations became established throughout Brazil, complaints regarding control failure have increased around the country. A broad survey to evaluate the susceptibility of horn flies to both organophosphate (OP) and pyrethroid insecticides was conducted from October 2000 to April 2003. Bioassays using filter papers impregnated with cypermethrin, permethrin or diazinon were conducted on 154 horn fly populations in 14 states and 78 municipalities. Resistance to cypermethrin, the active ...
Tópico(s): Insect behavior and control techniques
2012 - Colégio Brasileiro de Parasitologia Veterinaria | Revista Brasileira de Parasitologia Veterinária/Brazilian Journal of Veterinary Parasitology
Steven Baroletti, Heather Dell’Orfano,
... 1-Jul-2021. Alves-Silva J, Zuzarte M, Girão H and Salgueiro L (2021) The Role of ...
Tópico(s): Pharmaceutical Economics and Policy
2010 - Lippincott Williams & Wilkins | Circulation