Kathryn M. Harper, Darin J. Knapp, Ryan K. Butler, Cory A. Cook, Hugh E. Criswell, Garret D. Stuber, George R. Breese,
Background Chronic ethanol (EtOH) exposure induces neurobehavioral maladaptations in the brain though the precise changes have not been fully explored. The central nucleus of the amygdala ( CEA ) regulates anxiety‐like behavior induced by withdrawal from chronic intermittent EtOH ( CIE ) exposure, and the arginine vasopressin ( AVP ) system within the CEA regulates many anxiety‐like behaviors. Thus, adaptations occur in the CEA AVP system due to chronic EtOH exposure, which lead to anxiety‐like behaviors in ...
Tópico(s): Stress Responses and Cortisol
2019 - Wiley | Alcoholism Clinical and Experimental Research
William T. Hale, Matthew E. Wilhelm, Kyle A. Palmer, Matthew D. Stuber, George M. Bollas,
The increasing uncertainty due to advances in modern systems has negatively impacted system health and safety. System health and safety problems associated with uncertainty can be attributed to (1) inadequate system design, (2) ill-suited controller and operating envelope, and (3) lack of robustness in system diagnostics. The latter issue (3) is the main focus of this paper. This work presents an algorithm for the design of active fault detection and isolation (FDI) tests that provide rigorous guarantees ...
Tópico(s): Reliability and Maintenance Optimization
2019 - Elsevier BV | Computers & Chemical Engineering
William T. Branch, Calvin L. Chou, Neil J. Farber, David Hatem, Craig R. Keenan, Gregory Makoul, Mariah A. Quinn, William Salazar, Jane S. Sillman, Margaret L. Stuber, LuAnn Wilkerson, George Mathew, Michael Fost,
There is increased emphasis on practicing humanism in medicine but explicit methods for faculty development in humanism are rare. We sought to demonstrate improved faculty teaching and role modeling of humanistic and professional values by participants in a multi-institutional faculty development program as rated by their learners in clinical settings compared to contemporaneous controls. Blinded learners in clinical settings rated their clinical teachers, either participants or controls, on the ...
Tópico(s): Reflective Practices in Education
2014 - Springer Science+Business Media | Journal of General Internal Medicine
Banu Aygün, Adam Lane, Luke R. Smart, Brígida Santos, Léon Tshilolo, Thomas N. Williams, Peter Olupot‐Olupot, Susan E. Stuber, George Tomlinson, Teresa S. Latham, Russell E. Ware,
Realizing Effectiveness Across Continents with Hydroxyurea (REACH) is an open-label non-randomised trial of hydroxyurea (hydroxycarbamide) in children with sickle cell anaemia in sub-Saharan Africa. The short-term results of REACH on safety, feasibility, and effectiveness of hydroxyurea were published previously. In this paper we report results from extended hydroxyurea treatment in the REACH cohort up to 8 years.
Tópico(s): Myeloproliferative Neoplasms: Diagnosis and Treatment
2024 - Elsevier BV | The Lancet Haematology
Rex E. Wiederanders, Roscoe V. Stuber, Carlos Bolli Mota, Daniel J. O’Connell, George J. Haslam,
... Grading Prostatic Carcinoma Rex E. Wiederanders, Roscoe V. Stuber, Carlos Mota, Daniel O’Connell, and George J. Haslam Rex E. WiederandersRex E. Wiederanders More articles by this author , Roscoe V. StuberRoscoe V. Stuber More articles by this author , Carlos MotaCarlos Mota ... Wiederanders More articles by this author Roscoe V. Stuber More articles by this author Carlos Mota More articles by this author Daniel O’Connell More articles by this author George J. Haslam More articles by this author Expand ...
Tópico(s): AI in cancer detection
1963 - Lippincott Williams & Wilkins | The Journal of Urology
Friederike Petzold, Katy Billot, Xiaoyi Chen, C. Henry, Emilie Filhol, Yoann Martin, Marina Avramescu, Maxime Douillet, Vincent Morinière, Pauline Krug, Marc Jeanpierre, Kálmán Tory, Olivia Boyer, Anita Burgun, Aude Servais, Rémi Salomon, Alexandre Benmerah, Laurence Heidet, Nicolas Garcelon, Corinne Antignac, Mohamad Zaidan, Sophie Saunier, Tania Attié‐Bitach, Valerie Comier-Daire, Jean‐Michel Rozet, Yaacov Frishberg, Brigitte Llanas, M. Broyer, Nabil Mohsin, Marie‐Alice Macher, Nicole Philip, Véronique Baudouin, D. Brackman, Chantal Loirat, Marina Charbit, Maud Dehennault, C. Guyot, Pierre Bataille, Mariet Elting, Georges Deschênes, Andrea Gropman, Geneviève Guest, Marie‐France Gagnadoux, Philippe Nicoud, Pierre Cochat, Bruno Ranchin, A Bensman, Anne‐Marie Guerrot, Bertrand Knebelmann, İlmay Bilge, Bruno Daniele, Stéphane Burtey, Caroline Rousset Rouvière, Valérie Caudwell, Denis Morin, Hélène Dollfus, Anne Maisin, Christian Hamel, Éric Bieth, Sophie Gié, Judith Goodship, G. Roussey, Hermine La Selve, Hubert Nivet, Lucie Bessenay, Mathilde Caillez, Jean Bernard Palcoux, Stéphane L. Benoit, Philippe Dubot, Marc Fila, Fabienne Giuliano, Daouya Iftene, M. Kessler, Thérèsa Kwon, A. Lahoche, Audrey Laurent, Anne-Laure Leclerc, David V. Milford, Thomas J. Neuhaus, Sylvie Odent, Philippe Eckart, Dominique Chauveau, Patrick Niaudet, Horacio A. Repetto, Sophie Taque, Alexandra Bruel, Alexandra Noel-Botte, Emma Allain Launay, Lisa Allard, Dany Anlicheau, Anne-Laure Adra, Arnaud Garnier, Arvind Nagra, Remy Baatard, Justine Bacchetta, Banu Sadıkoğlu, Christine Barnérias, Anne Barthélémy, Lina Basel, Nader Bassilios, Hédi Ben Maïz, Fatma Ben Moussa, Faïza Benmati, Romain Berthaud, Aurélia Bertholet, Dominique Blanchier, J.J. Boffa, Karim Bouchireb, Ihab Bouhabel, Zakaria Boukerroucha, Guylhène Bourdat-Michel, Odile Boute, Karine Brochard, Roseline Caumes, Siham Chafai Elalaoui, B Chamontin, Marie Caroline Chastang, Christine Piètrement, Christine Richer, Christophe Legendre, Karin Dahan, Fabienne Dalla‐Vale, Damien Thibaudin, M. Dauvergne, Salandre Davourie, Martin M. DeBeukelaer, Jean‐Daniel Delbet, Constantinos Deltas, Denis Graber, Nadège Devillars, Boucar Diouf, Martine Doco Fenzy, Jean-Luc André, Dominique Joly, Alan Fryer, Laetitia Albano, Élisabeth Cassuto, A. Pinçon, Ana Medeira, Annabelle Chaussenot, Anne Mensire-Marinier, François Bouissou, Stéphane Decramer, Armand Bottani, Aurélie Hummel, Alexandre Karras, A. Katz, Christine Azéma, Bénédicte Janbon, Bernard Roussel, Claude Bonniol, Christiophe Mariat, Gérard Champion, Deborah Chantreuil, Nicolas Chassaing, Christiane Mousson, Christine Baudeau, Delphine Hafdar Cuntz, Cyril Mignot, Laurène Dehoux, Didier Lacombe, Thierry Hannedouche, Élodie Merieau, Emmanuelle Charlin, Eric Gauthier, Florent Plasse, Stanislas Faguer, Fanny Lebas, Florence Démurger, Francesco Emma, François Cartault, Geneviève Dumont, Nathalie Godefroid, Vincent Guigonis, Sophie Hillaire, Jaap W. Groothoff, Jan Dudley, Noémie Jourde‐Chiche, Khalil El Karoui, Saoussen Krid, Krier Coudert, Larbi Bencheick, L Yver, Marie‐Pierre Lavocat, Le Monies De Sagazan, Valériane Leroy, Lise Thibaudin, Liz Ingulli, Lorraine Gwanmesia, Lydie Bürglen, Marie-Hélène Saïd-Menthon, Marta Carrera, Mathilde Nizon, Catherine Melander, M Foulard, Monique Blayo, J Prinseau, Nadine Jay, Nathalie Brun, Nicolas Camille, François Nobili, Olivier Devuyst, Ouafa Ben Brahim, Paloma Parvex, Laurence Perrin Sabourin, Philippe Blanc, Philippe Vanhille, Pierre Galichon, Sophie Pierrepont, Vincent Planquois, Gwenaelle Poussard, Claire Pouteil Noble, Radia Allal, Raphaelle Bernard, Raynaud Mounet, R. Cahen, Renaud Touraine, Claire Rigothier, Amélie Ryckewaert, M. Sacquépée, Salima El Chehadeh, Charlotte Samaille, Shuman Haq, Ari M. Simckes, S. Lanoiselée, Stéphanie Tellier, Jean-François Subra, Sylvie Cloarec, Julie Tenenbam, T. Lamy, Valérie Drouin Garraud, H. Valette, Vanina Meyssonnier, Rosa Vargas‐Poussou, Yves Snajer, Sandrine Durault, Emmanuelle Plaisier, E. Bérard, Fádi Fakhouri, Férielle Louillet, P. Finielz, Michel Fischbach, B. Foliguet, Hélène Francois-Pradier, Florentine Garaix, Marion Gérard, Gianfranco Rizzoni, Brigitte Gilbert, Denis Glotz, Astrid Godron Dubrasquet, Jean‐Pierre Grünfeld, Guillaume Bollée, Michelle Hall, Sverker Hansson, Damien Haye, Hélène Taffin, Friedhelm Hildebrandt, Maryvonne Hourmand, Hümya Kayserili, Ivan Tack, Marie Line Jacquemont, Jennifer Fabre-Teste, Cliff Kashtan, K Van Hoeck, Alexandre Klein, Yannick Knefati, Nine V.A.M. Knoers, Martin Konrad, Alain Lachaux, Isabelle Landru, Gilbert Landthaler, Philippe Lang, P. Le Pogamp, Tristan Legris, Catherine Didailler, T. Lobbedez, L de Parscau, Lucile Pinson, H. Maheut, Marc Duval-Arnould, Marlène Rio, Marie‐Claire Gubler, Pierre Merville, Guillaume Mestrallet, M. Meunier, Karine Moreau, Jérôme Harambat, Graeme Morgan, Georges Mourad, Niksic Stuber, Odile Boespflug‐Tanguy, Olivier Dunand, Olivier Niel, Nacéra Ouali, Paolo Malvezzi, Pauline Abou Jaoude,
Nephronophthisis (NPH) is an autosomal-recessive ciliopathy representing one of the most frequent causes of kidney failure in childhood characterized by a broad clinical and genetic heterogeneity. Applied to one of the worldwide largest cohorts of patients with NPH, genetic analysis encompassing targeted and whole exome sequencing identified disease-causing variants in 600 patients from 496 families with a detection rate of 71%. Of 788 pathogenic variants, 40 known ciliopathy genes were identified. ...
Elsevier BV
Patrick T. McGann, Léon Tshilolo, Brígida Santos, George Tomlinson, Susan E. Stuber, Teresa S. Latham, Banu Aygün, Stephen Obaro, Peter Olupot‐Olupot, Thomas N. Williams, Isaac Odame, Russell E. Ware,
Background Sickle cell anemia (SCA) is an inherited hematological disorder that causes a large but neglected global health burden, particularly in Africa. Hydroxyurea represents the only available disease‐modifying therapy for SCA, and has proven safety and efficacy in high‐resource countries. In sub‐Saharan Africa, there is minimal use of hydroxyurea, due to lack of data, absence of evidence‐based guidelines, and inexperience among healthcare providers. Procedure A partnership was established between ...
Tópico(s): Epigenetics and DNA Methylation
2015 - Wiley | Pediatric Blood & Cancer
Philip Robinson, Denise Stuber, François Deryckère, Philip R. Tedbury, Magali Lagrange, Georges Orfanoudakis,
‘High-risk’ human papilloma viruses (HPVs) cause cervical tumours. In order to treat these tumours therapeutic approaches must be developed that efficiently target the tumour cells. Using phage display, we selected tumour-targeting peptides from a library of constrained nonamer peptides presented multivalently on pVIII of M13. Three different consensus peptide sequences were isolated by biopanning on HPV16-transformed SiHa cells. The corresponding phage-peptides targeted and were internalized in ...
Tópico(s): Virus-based gene therapy research
2004 - Wiley | Journal of Molecular Recognition
A.M. Fisher, John K. Harting, George F. Martin, M.I. Stuber,
Details of the corticospinal tract of the armadillo, a representative of order Edentata, are described for the first time in this study. Corticospinal fibers arise both rostral and caudal to the supraorbital sulcus. In the spinal cord they travel within the dorsal part of the ventral funiculus and within the lateral funiculus. Most of the fibers crossed at the pyramidal decussation. A few fascicles cross more caudally within the cord and a very few terminate on their side of origin. Corticospinal ...
Tópico(s): Veterinary Equine Medical Research
1969 - Elsevier BV | Journal of the Neurological Sciences
György Stuber, Joakim Dillner, Susanne Modrow, Hans Wolf, László Székely, George Klein, Eva Klein,
B lymphocytes immortalized with EBV in vitro, lymphoblastoid cell lines (LCL), express eight EBV-encoded proteins, EBV nuclear antigens -1 to -6 (EBNA-1 to -6), and latent membrane proteins 1 and 2 (LMP 1 and 2). After appropriate stimulations of blood lymphocytes from seroposltive individuals, MHC-restricted cytotoxic T cells (CTL), which lyse LCL cells, can be generated in vitro.Such CTLs can recognize EBNA-2 to -6, and LMP 1 and 2, but not EBNA-1-derived peptides presented on the cell surfaces. We posed ...
Tópico(s): Immunotherapy and Immune Responses
1995 - Oxford University Press | International Immunology
Recension
Tópico(s): Historical and Literary Studies
2001 - University of Bern | Swiss Journal of Educational Research
Gitsios Gitsioudis, Yiannis S. Chatzizisis, P.J. van der Wolf, Anna Missiou, Antonios Antoniadis, Dimitrios Mitsouras, Sönke Bartling, Zeynep Arica, Matthias Stuber, Frank J. Rybicki, Max Nunninger, Christian Erbel, Peter Libby, George D. Giannoglou, Hugo A. Katus, Grigorios Korosoglou,
To evaluate the incremental value of low endothelial shear stress (ESS) combined with high-resolution magnetic resonance imaging (MRI)- and computed tomography angiography (CTA)-based imaging for the prediction of inflamed plaque. Twelve hereditary hyperlipidaemic rabbits underwent quantitative analysis of plaque in the thoracic aorta with 256-slice CTA and USPIO-enhanced (ultra-small superparamagnetic nanoparticles, P904) 1.5-T MRI at baseline and at 6-month follow-up. Computational fluid dynamics ...
Tópico(s): Aortic Thrombus and Embolism
2016 - Oxford University Press | European Heart Journal - Cardiovascular Imaging
György Stuber, Karin Mattsson, Emilie Flaberg, Emrah Kati, László Márkász, Julie Sheldon, George Klein, Thomas F. Schulz, László Székely,
Abstract The latency-associated nuclear antigen (LANA-1) of Human Herpes Virus 8 (HHV-8), alternatively called Kaposi Sarcoma Herpes Virus (KSHV) is constitutively expressed in all HHV-8 infected cells. LANA-1 accumulates in well-defined foci that co-localize with the viral episomes. We have previously shown that these foci are tightly associated with the borders of heterochromatin [1]. We have also shown that exogenously expressed LANA-1 causes an extensive re-organization of Hoechst 33248 DNA staining ...
Tópico(s): Herpesvirus Infections and Treatments
2007 - BioMed Central | Molecular Cancer
Patrick T. McGann, Thomas N. Williams, Peter Olupot‐Olupot, George Tomlinson, Adam Lane, José Luís Reis da Fonseca, Robert Kitenge, George Mochamah, Ham Wabwire, Susan E. Stuber, Thad A. Howard, Kathryn E. McElhinney, Banu Aygün, Teresa S. Latham, Brígida Santos, Léon Tshilolo, Russell E. Ware,
Despite its well-described safety and efficacy in the treatment of sickle cell anemia (SCA) in high-income settings, hydroxyurea remains largely unavailable in sub-Saharan Africa, where more than 75% of annual SCA births occur and many comorbidities exist. Realizing Effectiveness Across Continents with Hydroxyurea (REACH, ClinicalTrials.gov NCT01966731) is a prospective, Phase I/II open-label trial of hydroxyurea designed to evaluate the feasibility, safety, and benefits of hydroxyurea treatment for ...
Tópico(s): Iron Metabolism and Disorders
2018 - Wiley | American Journal of Hematology
Rachel A. Annunziato, John C. Bucuvalas, Wanrong Yin, Ravinder Arnand, Estella M. Alonso, George Mazariegos, Robert S. Venick, Margaret L. Stuber, Benjamin L. Shneider, Eyal Shemesh,
To further refine a measure of self-management, the Responsibility and Familiarity with Illness Survey (REFILS), and to determine if this score predicts medication adherence and, thus, fewer instances of allograft rejection among pediatric liver transplant recipients.Participants were 400 liver transplant recipients and their parents recruited for the Medication Adherence in Children Who Had a Liver Transplant study, from 5 US pediatric transplant centers. The REFILS was administered to participants ( ...
Tópico(s): Family Support in Illness
2017 - Elsevier BV | The Journal of Pediatrics
György Stuber, Susanne Modrow, Petter Höglund, Lars Franksson, John Elvin, Hans Wolf, Klas Kärre, George Klein,
Abstract Earlier findings indicate that peptides can affect the expression of major histocompatibility complex (MHC) class I molecules on the surface of cells with defective peptide loading mechanism. We have used peptide induced increase of class I antigen expression to assess peptide interaction with MHC class I molecules. A panel of 41 overlapping synthetic peptides derived from the human immunodeficiency virus‐1 (HIV‐1) gag protein and 33 nonoverlapping peptides from Epstein‐Barr virus (EBV) proteins ...
Tópico(s): HIV Research and Treatment
1992 - Wiley | European Journal of Immunology
Rachel A. Annunziato, Margaret L. Stuber, Christina Supelana, Claire Dunphy, Ravinder Anand, Jinson Erinjeri, Estella M. Alonso, George Mazariegos, Robert S. Venick, John C. Bucuvalas, Eyal Shemesh,
Abstract PTSS as well as symptoms of depression have been reported in children who experience a serious medical adversity as well as their caretakers. The adverse effects of PTSS, when experienced by the patients, on medical outcomes have been clearly documented. However, the impact of those symptoms, if any, when experienced by the caretakers on child outcomes has not been investigated prospectively. We evaluated whether caregiver PTSS and depression symptoms predict adherence to medications and ...
Tópico(s): Family and Patient Care in Intensive Care Units
2019 - Wiley | Pediatric Transplantation
Courtney West, Lori Graham, Ryan Palmer, Marissa Fuqua Miller, Erin K. Thayer, Margaret L. Stuber, Linda Awdishu, Rachel Umoren, Maria Wamsley, Elizabeth A. Nelson, Pablo Joo, James W. Tysinger, Paul George, Patricia A. Carney,
Enhanced patient outcomes and accreditation criteria have led schools to integrate interprofessional education (IPE). While several studies describe IPE curricula at individual institutions, few examine practices across multiple institutions. To examine the IPE integration at different institutions and determine gaps where there is potential for improvement. In this mixed methods study, we obtained survey results from 16 U.S. medical schools, 14 of which reported IPE activities. The most common collaboration ...
Tópico(s): Healthcare Systems and Technology
2016 - Elsevier BV | Journal of Interprofessional Education & Practice
György Stuber, Gerhard Leder, Walter J. Storkus, Michael T. Lotze, Susanne Modrow, László Székely, Hans Wolf, Eva Klein, Klas Kärre, George Klein,
Abstract Mutations of the p53 gene are the most frequently observed genetic changes in human cancers; often leading to an overexpression of the wild‐type (wt) p53 protein. Demonstrable T cell reactivity against tumor cells overexpressing wt or mutant p53‐derived peptides could support the application of such epitopes in cancer immunotherapies. As the binding of peptide to MHC class I molecules is a prerequisite for antigen‐specific T cell recognition, we evaluated the ability of wt and mutant p53 ...
Tópico(s): Cancer Immunotherapy and Biomarkers
1994 - Wiley | European Journal of Immunology
Emilie Flaberg, László Márkász, Gabor Petrányi, György Stuber, F. Dicső, Nidal Alchihabi, Éva Oláh, István Csízy, Tamás Józsa, Ove Andrén, Jan‐Erik Johansson, Swen‐Olof Andersson, George Klein, László Székely,
Increasing evidence indicates that cancer development requires changes both in the precancerous cells and in their microenvironment. To study one aspect of the microenvironmental control, we departed from Michael Stoker's observation (Stroker et al, J Cell Sci 1966;1:297-310) that normal fibroblasts can inhibit the growth of admixed cancer cells (neighbour suppression). We have developed a high-throughput microscopy and image analysis system permitting the examination of live mixed cell cultures growing ...
Tópico(s): 3D Printing in Biomedical Research
2010 - Wiley | International Journal of Cancer
Peter J. Whitman, Floro F. Frulla, George H. Temme, F. A. Stuber,
Contrary to earlier reports, the formation of bis(aminophenyl) methanes in the acid-catalyzed condensation of aniline and formaldehyde can result in carbon—carbon bond cleavage proceeding via an ipso protodealkylation mechanism.
Tópico(s): Fluorine in Organic Chemistry
1986 - Elsevier BV | Tetrahedron Letters
György Stuber, Emilie Flaberg, Gabor Petrányi, Rita Ötvös, Nina Rökaeus, Elena Kashuba, Klas G. Wiman, George Klein, László Székely,
The low molecular weight compound, PRIMA-1MET restores the transcriptional transactivation function of certain p53 mutants in tumor cells. We have previously shown that PRIMA-1MET induces nucleolar translocation of p53, PML, CBP and Hsp70. The Epstein-Barr virus encoded, latency associated antigen EBNA-5 (also known as EBNA-LP) is required for the efficient transformation of human B lymphocytes by EBV. EBNA-5 associates with p53-hMDM2-p14ARF complexes. EBNA-5 is a nuclear protein that translocates ...
Tópico(s): Cancer-related Molecular Pathways
2009 - BioMed Central | Molecular Cancer
Léon Tshilolo, George Tomlinson, Thomas N. Williams, Brígida Santos, Peter Olupot‐Olupot, Adam Lane, Banu Aygün, Susan E. Stuber, Teresa S. Latham, Patrick T. McGann, Russell E. Ware,
Hydroxyurea is an effective treatment for sickle cell anemia, but few studies have been conducted in sub-Saharan Africa, where the burden is greatest. Coexisting conditions such as malnutrition and malaria may affect the feasibility, safety, and benefits of hydroxyurea in low-resource settings.
Tópico(s): Myeloproliferative Neoplasms: Diagnosis and Treatment
2018 - Massachusetts Medical Society | New England Journal of Medicine
Brígida Santos, Maria Nakafeero, Adam Lane, Léon Tshilolo, Thomas N. Williams, Peter Olupot‐Olupot, Janet M. Adams, Banu Aygün, Susan E. Stuber, George Tomlinson, Teresa S. Latham, Patrick T. McGann, Russell E. Ware,
Introduction: Transcranial Doppler (TCD) screening data from Uganda, Tanzania, and Nigeria have documented elevated velocities in >20% of children with sickle cell anemia (SCA) not receiving hydroxyurea treatment. Realizing Effectiveness Across Continents with Hydroxyurea (REACH, NCT01966731) has demonstrated the safety, feasibility, and benefits of hydroxyurea for children with SCA living in sub-Saharan Africa, especially when escalated to maximum tolerated dose (MTD). Whether hydroxyurea also confers ...
Tópico(s): Bone and Joint Diseases
2020 - Elsevier BV | Blood
Banu Aygün, Adam Lane, Luke R. Smart, Léon Tshilolo, Thomas N. Williams, Peter Olupot‐Olupot, Brígida Santos, Susan E. Stuber, George Tomlinson, Teresa S. Latham, Russell E. Ware,
Introduction: Realizing Effectiveness Across Continents with Hydroxyurea (REACH, NCT01966731) is an open-label multi-country prospective trial of hydroxyurea for children with sickle cell anemia (SCA) in sub-Saharan Africa (Angola, Democratic Republic of Congo, Kenya, and Uganda). Initial results documented the feasibility, safety, and benefits of hydroxyurea treatment with dose escalation to maximum tolerated dose (MTD), but further hydroxyurea dose optimization data are needed to assess long-term ...
Tópico(s): Iron Metabolism and Disorders
2023 - Elsevier BV | Blood
Dawn L. Rymer, Theresa A. Good,
... E. Hawkins J. Christie G. Davis J.B. George A. Karran E.H. Howlett D.R. Biochem. J. 2000; 348: 137-144Crossref PubMed Scopus (151) Google Scholar, 15Seilheimer B. Bohrmann B. Bondolfi L. Muller F. Stuber D. Dobeli H. J. Struct. Biol. 1997; 119: ...
Tópico(s): Endoplasmic Reticulum Stress and Disease
2001 - Elsevier BV | Journal of Biological Chemistry
Peter Olupot‐Olupot, George Tomlinson, Thomas N. Williams, Léon Tshilolo, Brígida Santos, Luke R. Smart, Kathryn E. McElhinney, Thad A. Howard, Banu Aygün, Susan E. Stuber, Adam Lane, Teresa S. Latham, Russell E. Ware,
Abstract Realizing Effectiveness Across Continents with Hydroxyurea (REACH, NCT01966731) provides hydroxyurea at maximum tolerated dose (MTD) for children with sickle cell anemia (SCA) in sub-Saharan Africa. Beyond reducing SCA-related clinical events, documented treatment benefits include ∼50% reduction in malaria incidence. To identify associations and propose mechanisms by which hydroxyurea could be associated with lower malaria rates, infections were recorded across all clinical sites (Angola, Democratic ...
Tópico(s): Myeloproliferative Neoplasms: Diagnosis and Treatment
2022 - Elsevier BV | Blood
... 2009;119(3):e182.] Crossref, Medline, Google Scholar2 Stuber M, Weiss RG. Coronary magnetic resonance angiography. J ... 23(5):752–756. Crossref, Medline, Google Scholar21 Stuber M, Botnar RM, Fischer SE, et al.. Preliminary ... 3):751–758. Link, Google Scholar27 Kim WY, Stuber M, Kissinger KV, Andersen NT, Manning WJ, Botnar ... 409. Link, Google Scholar30 Kim WY, Danias PG, Stuber M, et al.. Coronary magnetic resonance angiography for ... 345(26):1863–1869. Crossref, Medline, Google Scholar31 Stuber M, Botnar RM, Danias PG, et al.. Double- ...
Tópico(s): Advanced X-ray and CT Imaging
2011 - Radiological Society of North America | Radiology
Jin Ryoun Kim, Todd J. Gibson, Regina M. Murphy,
... 5Seilheimer B. Bohrman B. Bondolfi L. Muller F. Stuber D. Dobeli H. J. Struct. Biol. 1997; 119: ... 5Seilheimer B. Bohrman B. Bondolfi L. Muller F. Stuber D. Dobeli H. J. Struct. Biol. 1997; 119: ... E. Hawkins J. Christie G. Davis J.B. George A. Karran E.H. Howlett D.R. Biochem. ...
Tópico(s): Supramolecular Self-Assembly in Materials
2003 - Elsevier BV | Journal of Biological Chemistry
Nora D. Volkow, Marisela Morales,
... et al., 2009Owesson-White C.A. Ariansen J. Stuber G.D. Cleaveland N.A. Cheer J.F. ... involves the stria terminals and the ventral pallidum (Georges and Aston-Jones, 2001Georges F. Aston-Jones G. ... S. Moutkine I. Gardoni F. Huganir R.L. Georges F. Mameli M. Cocaine-evoked negative symptoms require ... involves the stria terminals and the ventral pallidum (Georges and Aston-Jones, 2001Georges F. Aston-Jones G. ... S. Moutkine I. Gardoni F. Huganir R.L. Georges F. Mameli M. Cocaine-evoked negative symptoms require ...
Tópico(s): Neuroscience and Neuropharmacology Research
2015 - Cell Press | Cell