Paola Losi, Enrica Briganti, Cesare Errico, A. Lisella, Elena Sanguinetti, Emo Chiellini, Giorgio Soldani,
Diabetic skin ulcers are difficult to heal spontaneously due to the reduced levels and activity of endogenous growth factors. Recombinant human vascular endothelial growth factor (VEGF) and basic fibroblast growth factor (bFGF) are known to stimulate cell proliferation and accelerate wound healing. Direct delivery of VEGF and bFGF at the wound site in a sustained and controllable way without loss of bioactivity would enhance their biological effects. The aim of this study was to develop a poly(ether) ...
Tópico(s): Pressure Ulcer Prevention and Management
2013 - Elsevier BV | Acta Biomaterialia
G. Natta, Giuseppe Allegra, I. W. Bassi, C. Carlini, Emo Chiellini, Giorgio Montagnoli,
ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTIsomorphism Phenomena in Isotactic Poly(4-methyl-substituted α-olefins) and in Isotactic Poly(alkyl vinyl ethers)G. Natta, G. Allegra, I. W. Bassi, C. Carlini, E. Chiellini, and G. MontagnoliCite this: Macromolecules 1969, 2, 4, 311–315Publication Date (Print):July 1, 1969Publication History Published online1 May 2002Published inissue 1 July 1969https://pubs.acs.org/doi/10.1021/ma60010a001https://doi.org/10.1021/ma60010a001research-articleACS PublicationsRequest ...
Tópico(s): Inorganic and Organometallic Chemistry
1969 - American Chemical Society | Macromolecules
Emo Chiellini, Giorgio Montagnoli, P. Pino,
Journal of Polymer Science Part B: Polymer LettersVolume 7, Issue 2 p. 121-127 Article Stereoselectivity in vinylethers polymerization E. Chiellini, E. Chiellini Instituto di Chimica Organica Industriale, Centro Nazionale di Chimica delle Macromolecole, del Consiglio Nazionale delle Ricerche, Sezione IV, Università di Pisa, ItalySearch for more papers by this authorG. Montagnoli, G. Montagnoli Instituto di Chimica Organica Industriale, Centro Nazionale di Chimica delle Macromolecole, del Consiglio ...
Tópico(s): biodegradable polymer synthesis and properties
1969 - Inderscience Publishers | Journal of Polymer Science Part B Polymer Letters
Ferri Marcella, Emo Chiellini, Pili Giorgio, Grimaldi Luca, Elena Tiziana Florio, Pili Stefania, Cucci Francesco, Latini Giuseppe,
Irradiation with 20-25 kGy is a process commonly used for sterilizing poly(vinyl chloride) (PVC) medical devices. Moreover, whole blood and blood components undergo additional irradiation with 25-50 Gy to inhibit the proliferative capacity of lymphocytes and reduce the risk of transfusion-associated graft-vs-host disease (GVHD). Di-(2-ethylhexyl)-phthalate (DEHP) plasticized PVC is extensively used for the production of flexible medical devices including blood bags, but since DEHP is not covalently ...
Tópico(s): Polymer Science and PVC
2012 - Elsevier BV | International Journal of Pharmaceutics
Verena Burk, Christoph G. Grimmer,
Im Beitrag wird untersucht, ob und mit welchen Strategien Athleten sowie Sportorganisationen in Krisen des Sports Soziale Medien in ihrer Krisenkommunikation verwenden. Ausgehend von der Theorie der situationsbezogenen Krisenkommunikation (SCCT) nach Coombs (1995; 2010), der bei verschiedenen Krisentypen spezifische Kommunikationsstrategien empfiehlt, werden Facebook-Posts und Tweets/Retweets von Spielern und Verbänden bei zwei ausgewählten Krisen während der Fußball-WM 2014 (Ausscheiden Spaniens in ...
Tópico(s): Social Media and Politics
2016 - De Gruyter | Sport und Gesellschaft
Carlo Pretti, Matteo Oliva, Roberta Di Pietro, Gianfranca Monni, Giorgio Cevasco, Emo Chiellini, Christian Silvio Pomelli, Cinzia Chiappe,
The ecotoxicity of pristine graphene nanoparticles (GNC1, PGMF) in model marine organisms was investigated. PGMF resulted more toxic than GNC1 to the bioluminescent bacterium Vibrio fischeri and the unicellular alga Dunaliella tertiolecta on the basis of EC50 values (end-points: inhibition of bioluminescence and growth, respectively). No acute toxicity was demonstrated with respect to the crustacean Artemia salina although light microscope images showed the presence of PGMF and GNC1 aggregates into ...
Tópico(s): Carbon and Quantum Dots Applications
2014 - Elsevier BV | Ecotoxicology and Environmental Safety
Verena Burk, Christoph G. Grimmer,
Tópico(s): Public Relations and Crisis Communication
2016 - De Gruyter | Sport und Gesellschaft
M Barsotti, Tamer Al Kayal, Lorena Tedeschi, Dinuccio Dinucci, Paola Losi, Silverio Sbrana, Enrica Briganti, Rodorico Giorgi, Emo Chiellini, Rossella Di Stefano, Giorgio Soldani,
As the endothelium still represents the ideal surface for cardiovascular devices, different endothelialization strategies have been attempted for biocompatibility and nonthrombogenicity enhancement. Since endothelial progenitor cells (EPCs) could accelerate endothelialization, preventing thrombosis and restenosis, the aim of this study was to use oligonucleotides (ONs) to biofunctionalize stents for EPC binding. In order to optimize the functionalization procedure before its application to cobalt- ...
Tópico(s): Electrospun Nanofibers in Biomedical Applications
2015 - Wiley | Journal of Biomedical Materials Research Part A
Mario Giuffrida, Pietro Maravigna, Giorgio Montaudo, Emo Chiellini,
Abstract Some bipolyesters consisting of 1,2‐propene glycol residue (P) and symmetric aromatic diacid residue constituted by two p ‐oxybenzoyl groups coupled by a terephthaloyl (HTH), phthaloyl (HOH) and isophthaloyl (HIH) group, and a nonsymmetric diacid residue constituted by a p ‐oxybenzoyl and a terephthaloyl group (HT), have been investigated by direct pyrolysis–mass spectrometry. The results show that intramolecular exchange reactions occurring at the pyrolysis stage cause a reorganization of the ...
Tópico(s): Polymer Nanocomposites and Properties
1986 - Wiley | Journal of Polymer Science Part A Polymer Chemistry
M Barsotti, A. Magera, Chiara Armani, Emo Chiellini, Francesca Felice, D. Dinucci, Anna Maria Piras, A. Minnocci, Roberto Solaro, Giorgio Soldani, Alberto Balbarini, R. Di Stefano,
Objectives: Transplantation of endothelial progenitor cells (EPCs) is a promising approach for revascularization of tissue. We have used a natural and biocompatible biopolymer, fibrin, to induce cell population growth, differentiation and functional activity of EPCs. Materials and methods: Peripheral blood mononuclear cells were cultured for 1 week to obtain early EPCs. Fibrin was characterized for stiffness and capability to sustain cell population expansion at different fibrinogen–thrombin ratios. ...
Tópico(s): Platelet Disorders and Treatments
2010 - Wiley | Cell Proliferation
Alberto Dessy, Anna Maria Piras, Giorgio Schirò, Matteo Levantino, Antonio Cupane, Emo Chiellini,
In the present work polymeric nanoparticles based on Poly (maleic anhydride-alt-butyl vinyl ether) 5% grafted with m-PEG (2000) and 95% grafted with 2-methoxyethanol (VAM41-PEG) were loaded with human hemoglobin (Hb) and characterized from a physicochemical point of view. The assessment of structural and functional features of the loaded Hb was performed and the effect of the introduction of different reducing agents as aimed at minimizing Hb oxidation during the nanoparticles formulation process, was ...
Tópico(s): Nanoparticle-Based Drug Delivery
2011 - Elsevier BV | European Journal of Pharmaceutical Sciences
Marcella Ferri, Emo Chiellini, Giorgio Pili, Luca Grimaldi, Elena Tiziana Florio, Stefania Pili, F. Cucci, Giuseppe Latini,
Laboratory of Bioactive Polymeric Materials for Biomedical and Environmental Applications (BIOlab), Department Chemistry & Ind. Chemistry, University of Pisa, Pisa, Italy Medical Physics Department, Perrino Hospital, Brindisi, Italy School of Medicine, Catholic University, Rome, Italy Division of Neonatology, Perrino Hospital, Brindisi, Italy Clinical Physiology Institute, National Research Council of Italy (IFC-CNR), Italy
Tópico(s): Electrospun Nanofibers in Biomedical Applications
2012 - Elsevier BV | International Journal of Pharmaceutics
Di Stefano Rossella, Enrica Briganti, Chiara Mirtelli, Silvia Kull, Dario Spiller, Michela Balderi, M Barsotti, A. Magera, Roberta Arici, Elisa Simonetti, Barbara Battolla, O Dinucci, Chiara Ristori, Emo Chiellini, Giorgio Soldani, Alberto Balbarini,
Tópico(s): Bone Tissue Engineering Materials
2008 - Italian Society of Cardiac Surgery | Giornale italiano di cardiologia
M Barsotti, Emo Chiellini, A. Lisella, C Errico, Silvia Burchielli, Giorgio Soldani, R. Di Stefano,
Tópico(s): Inflammatory Biomarkers in Disease Prognosis
2012 - Italian Society of Cardiac Surgery | Giornale italiano di cardiologia
A. Magera, R. Di Stefano, M Barsotti, M. Lemmi, Ramazan ARICI, E Simonetti, D. Dinucci, Emo Chiellini, A. Minnocci, Michele Alderighi, Roberto Solaro, Giorgio Soldani, Alberto Balbarini,
Tópico(s): Blood properties and coagulation
2008 - Italian Society of Cardiac Surgery | Giornale italiano di cardiologia
Roberto Francischello, Salvatore Claudio Fanni, Martina Chiellini, Maria Febi, Giorgio Pomara, Claudio Bandini, Lorenzo Faggioni, Riccardo Lencioni, Emanuele Neri, Dania Cioni,
Tópico(s): Advanced X-ray and CT Imaging
2024 - Elsevier BV | European Journal of Radiology Open
M Barsotti, R. Di Stefano, Emo Chiellini, A. Lisella, C Errico, Roberto Feriani, Silvia Burchielli, Alberto Balbarini, Giorgio Soldani,
Purpose: Platelet lysate (PL) contains growth factors, cytokines and chemokines useful for angiogenesis and tissue repair. Polymer-based nanoparticles (NP) could be used as PL carriers for a controlled release in ischemia. Our aim was to characterize the in vitro (viability, tissue repair and inflammatory response activation) and in vivo (injection in rat ischemic hindlimb and Laser Doppler Perfusion Imaging, LDPI) effect of PL-loaded NP. Methods: Human umbilical vein endothelial cells (HUVEC) were obtained ...
Tópico(s): Periodontal Regeneration and Treatments
2013 - Oxford University Press | European Heart Journal