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Artigo Revisado por pares

M. Manzolaro, A. Andrighetto, Giovanni Meneghetti, M. Rossignoli, S. Corradetti, Lisa Biasetto, D. Scarpa, A. Monetti, S. Carturan, G. Maggioni,

Ion sources play a crucial role in ISOL (Isotope Separation On Line) facilities determining, with the target production system, the ion beam types available for experiments. In the framework of the SPES (Selective Production of Exotic Species) INFN (Istituto Nazionale di Fisica Nucleare) project, a preliminary study of the alkali metal isotopes ionization process was performed, by means of a surface ion source prototype. In particular, taking into consideration the specific SPES in-target isotope production, ...

Tópico(s): Fusion materials and technologies

2013 - Elsevier BV | Nuclear Instruments and Methods in Physics Research Section B Beam Interactions with Materials and Atoms

Artigo Revisado por pares

Giada Rossignoli, Alessandro Grottesi, Giovanni Bisello, Riccardo Montioli, Carla Borri Voltattorni, Alessandro Paiardini, Mariarita Bertoldi,

Histidine decarboxylase is a pyridoxal 5′-phosphate enzyme catalyzing the conversion of histidine to histamine, a bioactive molecule exerting its role in many modulatory processes. The human enzyme is involved in many physiological functions, such as neurotransmission, gastrointestinal track function, cell growth, and differentiation. Here, we studied the functional properties of the human enzyme and, in particular, the effects exerted at the protein level by two cysteine residues: Cys-180 and Cys- ...

Tópico(s): Enzyme Structure and Function

2018 - American Chemical Society | Biochemistry

Artigo Acesso aberto Revisado por pares

Riccardo Montioli, Giovanni Bisello, Mirco Dindo, Giada Rossignoli, Carla Borri Voltattorni, Mariarita Bertoldi,

AADC deficiency is a rare genetic disease caused by mutations in the gene of aromatic amino acid decarboxylase, the pyridoxal 5'-phosphate dependent enzyme responsible for the synthesis of dopamine and serotonin. Here, following a biochemical approach together with an in silico bioinformatic analysis, we present a structural and functional characterization of 13 new variants of AADC. The amino acid substitutions are spread over the entire protein from the N-terminal (V60A), to its loop1 (H70Y and ...

Tópico(s): Pancreatic function and diabetes

2020 - Elsevier BV | Archives of Biochemistry and Biophysics

Revisão Acesso aberto Revisado por pares

Giovanni Bisello, Carmen Longo, Giada Rossignoli, Robert S. Phillips, Mariarita Bertoldi,

Abstract The versatility of reactions catalyzed by pyridoxal 5′-phosphate (PLP) enzymes is largely due to the chemistry of their extraordinary catalyst. PLP is necessary for many reactions involving amino acids. Reaction specificity is controlled by the orientation of the external aldimine intermediate that is formed upon addition of the amino acidic substrate to the coenzyme. The breakage of a specific bond of the external aldimine gives rise to a carbanionic intermediate. From this point, the different ...

Tópico(s): Biochemical Acid Research Studies

2020 - Springer Science+Business Media | Amino Acids

Artigo Acesso aberto Revisado por pares

A. Andrighetto, M. Manzolaro, S. Corradetti, D. Scarpa, A. Monetti, M. Rossignoli, Michele Ballan, Francesca Borgna, F. D’Agostini, F. Gramegna, G. Prete, Giovanni Meneghetti, Matteo Ferrari, A. Zenoni,

The Isotope Separation On-Line (ISOL) method for the production of Radioactive Ion Beams (RIB) is attracting significant interest in the worldwide nuclear physics community. Within this context the SPES (Selective Production of Exotic Species) RIB facility is now under construction at INFN LNL (Istituto Nazionale di Fisica Nucleare Laboratori Nazionali di Legnaro). This technique is established as one of the main techniques for high intensity and high quality beams production. The SPES facility will ...

Tópico(s): Boron Compounds in Chemistry

2018 - IOP Publishing | Journal of Physics Conference Series

Artigo Revisado por pares

M. Manzolaro, A. Andrighetto, Giovanni Meneghetti, A. Monetti, D. Scarpa, M. Rossignoli, J. Vásquez, S. Corradetti, M. Calderolla, G. Prete,

An intense research and development activity to finalize the design of the target ion source system for the selective production of exotic species (SPES) facility (operating according to the isotope separation on line technique) is at present ongoing at Legnaro National Laboratories. In particular, the characterization of ion sources in terms of ionization efficiency and transversal emittance is currently in progress, and a preliminary set of data is already available. In this work, the off-line ionization ...

Tópico(s): Muon and positron interactions and applications

2014 - American Institute of Physics | Review of Scientific Instruments

Artigo Acesso aberto Revisado por pares

A. Galatà, C. Roncolato, G. Bisoffi, P Francescon, Luca Bellan, J. Bermudez, D. Bortolato, M. Comunian, A. Conte, M. De Lazzari, Fabio Gelain, Davide Marcato, M Miglioranza, M.F. Moisio, Enrico Munaron, Stefano Pavinato, D. Pedretti, A. Pisent, M. Rossignoli, M Roetta, Giovanni Savarese, M. Bellato, J. Angot, D. Bondoux, T. Thuillier, Vladimir Andreev,

Abstract The ADIGE (Acceleratore Di Ioni a Grande carica Esotici) injector of the SPES (Selective Production of Exotic Species) project is now in an advanced phase of installation. Its main components have been designed following particular needs of the project: first, an Electron Cyclotron Resonance (ECR)-based Charge Breeder (SPES-CB), to boost the charge states of the radioactive ions produced at SPES and allow their post-acceleration. Then, a stable 1+ source and a complete electrostatic beam line ...

Tópico(s): Nuclear Physics and Applications

2019 - IOP Publishing | Journal of Physics Conference Series

Artigo Revisado por pares

A. Galatà, C. Roncolato, P Francescon, G. Bisoffi, Luca Bellan, M. Bellato, J. Bermudez, D. Bortolato, M. Comunian, A. Conte, M. De Lazzari, Fabio Gelain, Davide Marcato, M Miglioranza, M.F. Moisio, Enrico Munaron, Stefano Pavinato, D. Pedretti, A. Pisent, M. Rossignoli, M Roetta, Giovanni Savarese, Vladimir Andreev,

Since fall 2017, the ADIGE (Acceleratore Di Ioni a Grande carica Esotici) injector of the SPES (Selective Production of Exotic Species) project entered the installation phase. The injector includes an Electron Cyclotron Resonance (ECR)-based Charge Breeder (SPES-CB) and its complete beam line, as well as a newly designed RFQ, to allow the post-acceleration of the radioactive ions produced in the so-called target-ion source-system. The injector has different peculiarities, deriving from particular needs ...

Tópico(s): Nuclear Physics and Applications

2018 - Institute of Physics | Journal of Instrumentation

Artigo Acesso aberto Revisado por pares

Giada Rossignoli, Karolin Krämer, Eleonora Lugarà, Haya Alrashidi, Simon Pope, Carmen De La Fuente Barrigon, Katy Barwick, Giovanni Bisello, Joanne Ng, John R. Counsell, Gabriele Lignani, Simon J.R. Heales, Mariarita Bertoldi, Serena Barral, Manju A. Kurian,

Aromatic l-amino acid decarboxylase (AADC) deficiency is a complex inherited neurological disorder of monoamine synthesis which results in dopamine and serotonin deficiency. The majority of affected individuals have variable, though often severe cognitive and motor delay, with a complex movement disorder and high risk of premature mortality. For most, standard pharmacological treatment provides only limited clinical benefit. Promising gene therapy approaches are emerging, though may not be either ...

Tópico(s): Pluripotent Stem Cells Research

2021 - Oxford University Press | Brain

Artigo Acesso aberto Revisado por pares

A. Monetti, A. Andrighetto, Carlo Petrovich, M. Manzolaro, S. Corradetti, D. Scarpa, Francesco Rossetto, Fernando Martinez Dominguez, Jesus Vásquez, M. Rossignoli, M. Calderolla, R. Silingardi, Aldo Mozzi, Francesca Borgna, G.A. Vivian, Enrico Boratto, Michele Ballan, G. Prete, Giovanni Meneghetti,

Facilities making use of the Isotope Separator On-Line (ISOL) method for the production of Radioactive Ion Beams (RIB) attract interest because they can be used for nuclear structure and reaction studies, astrophysics research and interdisciplinary applications. The ISOL technique is based on the fast release of the nuclear reaction products from the chosen target material together with their ionization into short-lived nuclei beams. Within this context, the SPES (Selective Production of Exotic Species) ...

Tópico(s): Nuclear reactor physics and engineering

2015 - Springer Science+Business Media | The European Physical Journal A

Artigo Acesso aberto Revisado por pares

Giorgio Gargari, Giacomo Mantegazza, Valentina Taverniti, Claudio Gardana, Alice Valenza, Federico Rossignoli, Maria Raffaella Barbaro, Giovanni Marasco, Cesare Cremon, Giovanni Barbara, Simone Guglielmetti,

The gut microbiota is believed to be a critical factor in the pathogenesis of IBS, and its metabolic byproducts, such as short-chain fatty acids (SCFAs), are known to influence gut function and host health. Despite this, the precise role of SCFAs in IBS remains a topic of debate. In this study, we examined the bacterial community structure by 16S rRNA gene profiling and SCFA levels by UPLC-MS/MS in fecal samples from healthy controls (HC; n = 100) and non-constipated patients (IBS-D and IBS-M; NC-IBS; ...

Tópico(s): Diet and metabolism studies

2023 - Landes Bioscience | Gut Microbes

Artigo Acesso aberto Revisado por pares

A. Adami, L. Fregonese, Daniela Lattanzi, Antonio Giovanni Mazzeri, Olga Rossignoli, Barbara Scala,

The “Palazzo Ducale” museum complex in Mantua has been the object of intermittent interventions, which have not represented, over the last 30 years, a consistent strategy in terms of conservation. In the light of new financial and technological possibilities, a renewed management synergy has been activated: better operative decisions and the application of innovative tools are the core of this attitude. The article illustrates the path of knowledge activated in the museum’s “Cortile della Cavallerizza”: ...

Tópico(s): Conservation Techniques and Studies

2019 - Multidisciplinary Digital Publishing Institute | Heritage

Artigo Acesso aberto Revisado por pares

A. Galatà, P Francescon, C. Roncolato, G. Bisoffi, Michele Ballan, Luca Bellan, J. Bermudez, D. Bortolato, M. Comunian, A. Conte, M. De Lazzari, E. Fagotti, Fabio Gelain, M. Manzolaro, Davide Marcato, Valentina Martinelli, M Miglioranza, M.F. Moisio, A. Monetti, Enrico Munaron, A. Pisent, M. Rossignoli, M Roetta, Giovanni Savarese, D. Scarpa,

Abstract The ADIGE (Acceleratore Di Ioni a Grande carica Esotici) injector consists of an electrostatic 1+ beam line, equipped with ion sources able to produce a wide variety of beams, coupled to a magnetic beam line, where charge multiplication is accomplished by implementing an Electron Cyclotron Resonance (ECR) based charge breeder. The injector is totally integrated in the SPES (Selective Production of Exotic Species) beam line, to allow the post-acceleration of radioactive ions and is now in an ...

Tópico(s): Muon and positron interactions and applications

2022 - IOP Publishing | Journal of Physics Conference Series

Artigo Acesso aberto Brasil Produção Nacional Revisado por pares

Marilza Vieira Cunha Rudge, Fátima Pereira de Souza, Joélcio Francisco Abbade, Raghavendra L. S. Hallur, J. P. C. Marcondes, Fernanda Pículo, G Marini, Giovana Vesentini, Lehana Thabane, Steven S. Witkin, Iracema de Mattos Paranhos Calderon, Angélica Mércia Pascon Barbosa, Marilza Vieira Cunha Rudge, Angélica Mércia Pascon Barbosa, Iracema de Mattos Paranhos Calderon, Fátima Pereira de Souza, Joélcio Francisco Abbade, L. S. R. Hallur, Fernanda Pículo, G Marini, Giovana Vesentini, Lehana Thabane, Marica Palma, Carlos F. O. Graeff, R. K. Arni, Rondinelli Donizetti Herculano, Daisy Maria Fávero Salvadori, Silvia Helena Rondina Mateus, Maeli Dal‐Pai‐Silva, Cláudia Garcia Magalhães, Roberto Costa, Silvana Andréa Molina Lima, Sérgio Luís Felisbino, W. Barbosa, Álvaro Nagib Atallah, Manoel Joâo Batista Castello Girão, Z. Di Bella, Silvana Maria de Macêdo Uchôa, Spencer Luíz Marques Payão, A. Hijas, B. Berghman, Rob A. de Bie, Luis Sobrevía, Baerbel Junginger, Fernanda Cristina Bérgamo Alves, Patrícia de Souza Rossignoli, Caroline Baldini Prudêncio, M. I. G. Orlandi, Maria Inês Rebelo Gonçalves, Sthefanie K. Nunes, B. B. Catinelli, Stephanie Mishell López Quiroz, Barbara Vaz Sarmento, Fabiane A. Pinheiro, C. I. Sartorão, R. R. Lucas, David Rafael Abreu Reyes, S. B. C. V. Quiroz, E. M. A. Enriquez, Rafael Guilen de Oliveira, Juliana Ferreira Floriano, J. P. C. Marcondes, S. Barneze, T. D. Dangió, T. Pascon, Patrícia de Souza Rossignoli, Juliana Vasconcellos de Freitas, Luiz Takano, F. V. D. S. Reis, T. D. Caldeirão, J. N. Fernandes, A. M. Carr, Maria Victoria Candida Gaitero, José Eduardo Corrente, Hilario Nunès, A. F. Candido, Sarah Maria Barneze Costa, T. D. Dangió, T. Pascon, Janyne Vilarinho Melo, Luiz Takano, F. V. D. S. Reis, T. D. Caldeirão, A. M. Carr, G. A. Garcia, G. B. Rabadan, H. C. M. Bassin, K Suyama, L. N. Damasceno, Maíra Libertad Soligo Takemoto, Mariane de Oliveira Menezes, Diego Girotto Bussaneli, V. K. C. Nogueira, Patrícia Rodrigues de Lima, I. O. Lourenço, Jéssica Maróstica de Sá, R. A. Megid, Ícaro Putinhon Caruso, L.‐T. RASMUSSEN, Giovanni Prata, Fernanda Pículo, Giovana Vesentini, Mariana Alvarez Arantes, Guilherme Augusto Rago Ferraz, Luciane Pires de Camargo, Meline Rossetto Kron Rodrigues, José Eduardo Corrente, Hilario Nunès,

Pelvic floor muscles (PFM) and rectus abdominis muscles (RAM) of pregnant diabetic rats exhibit atrophy, co-localization of fast and slow fibers and an increased collagen type I/III ratio. However, the role of similar PFM or RAM hyperglycemic-related myopathy in women with gestational diabetes mellitus (GDM) remains poorly investigated. This study aims to assess the frequency of pelvic floor muscle disorders and pregnancy-specific urinary incontinence (PS-UI) 12 months after the Cesarean (C) section ...

Tópico(s): Pregnancy-related medical research

2020 - BioMed Central | BMC Pregnancy and Childbirth

Artigo Acesso aberto Revisado por pares

Giovanni Bisello, Giada Rossignoli, Sarah Choi, Robert S. Phillips, Mariarita Bertoldi,

Aromatic amino acid decarboxylase is a pyridoxal 5'-phosphate-dependent enzyme responsible for the synthesis of the neurotransmitters, dopamine and serotonin. Here, by a combination of bioinformatic predictions and analyses, phosphorylation assays, spectroscopic investigations and activity measurements, we determined that Ser-193, a conserved residue located at the active site, can be phosphorylated, increasing catalytic efficiency. In order to determine the molecular basis for this functional improvement, ...

Tópico(s): Biotin and Related Studies

2023 - Elsevier BV | Biochemical and Biophysical Research Communications

Artigo Acesso aberto Brasil Produção Nacional Revisado por pares

David Rafael Abreu Reyes, Angélica Mércia Pascon Barbosa, Juliana Ferreira Floriano, Quiroz B. C. V. Sofia, Sarah Maria Barneze Costa, Raghavendra L. S. Hallur, E. M. A. Enriquez, Rafael Guilen de Oliveira, Patricia de Souza Rossignolli, Cristiane Rodrigues Pedroni, Fernanda Cristina Bérgamo Alves, G. A. Garcia, Joélcio Francisco Abbade, C. N. F. Carvalho, Luis Sobrevía, Marilza Vieira Cunha Rudge, Iracema I. M. P. Calderon, Fátima Pereira de Souza, T. Lehana, Carlos F. O. Graeff, Cláudia Garcia Magalhães, Roberto Costa, Silvana Andréa Molina Lima, Meline Rossetto Kron Rodrigues, Sérgio Luís Felisbino, W. F. Barbosa, F. J. Campos, G. Bossolan, José Eduardo Corrente, Hilario Nunès, Patrícia de Souza Rossignoli, Á. N. Atallah, Z. I. Jármy-Di Bella, Silvana Maria de Macêdo Uchôa, Marco Antônio Húngaro Duarte, Edson Assunção Mareco, M. E. Sakalem, Natália Martinho, Diego Girotto Bussaneli, M. I. G. Orlandi, C. Pascon, T. D. Dangió, Fernanda Pículo, Giovanni Prata, Raíssa Escandiusi Avramidis, A. B. M. Magyori, G. T. A. Nava, T. C. D. Caldeirão, R. H. L. Shetty, J. P. C. Marcondes, M.L.S. Takemoto, Caroline Baldini Prudêncio, Fabiane A. Pinheiro, Carlos Izaias Sartorão Filho, S. B. C. V. Quiroz, T. Pascon, Sthefanie K. Nunes, B. B. Catinelli, F. V. D. S. Reis, Mariane de Oliveira Menezes, N. J. Santos, Luiz Takano, A. M. Carr, L. F. Iamundo, H. C. M. Bassin, V. P. Barbosa, M. Jacomin, A. J. B. Silva, I. O. Lourenço, J. Marosticadesá, Ícaro Putinhon Caruso, L.‐T. RASMUSSEN, V. K. C. Nogueira, J. T. Ribeiro-Paes, Danielle Cristina Honório França, H. V. M. Bastos, M. L. A. Heliodoro, M. N. Kuroda, H. L. Carvalho,

Ex-vivo myography enables the assessment of muscle electrical activity response. This study explored the viability of determining the physiological responses in muscles without tendon, as rectus abdominis muscle (RAM), through ex-vivo myography to assess its potential as a diagnostic tool.All tested RAM samples (five different samples) show patterns of electrical activity. A positive response was observed in 100% of the programmed stimulation. RAM 3 showed greater weight (0.47 g), length (1.66 cm), ...

Tópico(s): Peripheral Nerve Disorders

2022 - BioMed Central | BioMedical Engineering OnLine

Artigo Brasil Produção Nacional Revisado por pares

Caroline Baldini Prudêncio, Sthefanie K. Nunes, Fabiane A. Pinheiro, C Isaias Sartorão Filho, Flávia Ignácio Antônio, Guilherme Thomaz de Aquino Nava, Marilza Vieira Cunha Rudge, Angélica Mércia Pascon Barbosa, Iracema de Mattos Paranhos Calderon, Fátima Pereira de Souza, Bary Berghmans, Rob A. de Bie, Lehana Thabane, Baerbel Junginger, Carlos F. O. Graeff, Cláudia Garcia Magalhães, Sarah Maria Barneze Costa, Silvana Andréa Molina Lima, M. R. Kron-Rodrigues, Sérgio Luís Felisbino, W. Barbosa, F. J. Campos, G. Bossolan, José Eduardo Corrente, Hilario Nunès, Joélcio Francisco Abbade, Patrícia de Souza Rossignoli, Cristiane Rodrigues Pedroni, Álvaro Nagib Atallah, Z. I. K. J. Di Bella, Silvana Maria de Macêdo Uchôa, M. A. Hungaro, Edson Assunção Mareco, M. E. Sakalem, Natália Martinho, L. S. R. Hallur, David Rafael Abreu Reyes, Fernanda Cristina Bérgamo Alves, J. P. C. Marcondes, S. B. C. V. Quiroz, T. Pascon, B. B. Catinelli, F. V. D. S. Reis, Rafael Guilen de Oliveira, S. Barneze, E. M. A. Enriquez, Luiz Takano, A. M. Carr, A. B. M. Magyori, L. F. Iamundo, C. N. F. Carvalho, M. Jacomin, Raíssa Escandiusi Avramidis, A. J. B. Silva, M. I. G. Orlandi, T. D. Dangió, H. C. M. Bassin, Janyne Vilarinho Melo, M.L.S. Takemoto, Mariane de Oliveira Menezes, T. D. Caldeirão, N. J. Santos, I. O. Lourenço, J. de Sá Marostica, Ícaro Putinhon Caruso, L.‐T. RASMUSSEN, G. A. Garcia, C. Pascon, Diego Girotto Bussaneli, V. K. C. Nogueira, Cibele Vieira Cunha Rudge, Fernanda Pículo, Giovanni Prata, V. P. Barbosa,

Tópico(s): Pelvic and Acetabular Injuries

2022 - Springer Science+Business Media | International Urogynecology Journal

Artigo Acesso aberto Brasil Produção Nacional Revisado por pares

B. B. Catinelli, Patrícia de Souza Rossignoli, Juliana Ferreira Floriano, A. M. Carr, Rafael Guilen de Oliveira, N. J. Santos, Lara Cristina Casadei Úbeda, Maria Angélica Spadella, Raghavendra L. S. Hallur, Luis Sobrevía, Sérgio Luís Felisbino, Iracema de Mattos Paranhos Calderon, Angélica Mércia Pascon Barbosa, Marilza V. C. Rudge, Marilza Vieira Cunha Rudge, Angélica Mércia Pascon Barbosa, Iracema de Mattos Paranhos Calderon, Luis Sobrevía, Fátima Pereira de Souza, Bary Berghmans, Lehana Thabane, Baerbel Junginger, Carlos F. O. Graeff, Cláudia Garcia Magalhães, Sarah Maria Barneze Costa, Silvana Andréa Molina Lima, M. R. Kron-Rodrigues, Sérgio Luís Felisbino, Walnei Fernandes Barbosa, F. J. Campos, G. Bossolan, José Eduardo Corrente, Hélio Rubens de Carvalho Nunes, Joélcio Francisco Abbade, Patrícia de Souza Rossignoli, Cristiane Rodrigues Pedroni, Álvaro Nagib Atallah, Z. I. K. J. Di Bella, Silvana Maria de Macêdo Uchôa, Marco Antônio Húngaro Duarte, Edson Assunção Mareco, M. E. Sakalem, Natália Martinho, L. S. R. Hallur, David Rafael Abreu Reyes, Fernanda Cristina Bérgamo Alves, J. P. C. Marcondes, Caroline Baldini Prudêncio, Fabiane A. Pinheiro, Carlos Izaias Sartorão Filho, S. B. C. V. Quiroz, T. Pascon, Sthefanie K. Nunes, B. B. Catinelli, F. V. D. S. Reis, Rafael Guilen de Oliveira, S. Barneze, E. M. A. Enriquez, Luiz Takano, A. M. Carr, A. B. M. Magyori, L. F. Iamundo, C. N. F. Carvalho, M. Jacomin, Raíssa Escandiusi Avramidis, A. J. B. Silva, M. I. G. Orlandi, T. D. Dangió, H. C. M. Bassin, Maíra Libertad Soligo Takemoto, T. D. Caldeirão, N. J. Santos, I. O. Lourenço, Jéssica Maróstica de Sá, Ícaro Putinhon Caruso, L.‐T. RASMUSSEN, G. A. Garcia, G. T. A. Nava, Catarina Marques, Diego Girotto Bussaneli, V. K. C. Nogueira, Cibele Vieira Cunha Rudge, Fernanda Pículo, Giovanni Prata, V. P. Barbosa,

Gestational diabetes mellitus (GDM) plus rectus abdominis muscle (RAM) myopathy predicts long-term urinary incontinence (UI). Atrophic and stiff RAM are characteristics of diabetes-induced myopathy (DiM) in pregnant rats. This study aimed to determine whether swimming exercise (SE) has a therapeutic effect in mild hyperglycemic pregnant rats model. We hypothesized that SE training might help to reverse RAM DiM. Mild hyperglycemic pregnant rats model was obtained by a unique subcutaneous injection of ...

Tópico(s): Pregnancy-related medical research

2022 - Nature Portfolio | Scientific Reports

Artigo Acesso aberto Revisado por pares

Michela Lo Conte, Valeria Lucchino, Stefania Scalise, Clara Zannino, Desirèe Valente, Giada Rossignoli, Maria Stella Murfuni, Chiara Cicconetti, Luana Scaramuzzino, Danilo Swann Matassa, Anna Procopio, Graziano Martello, Giovanni Cuda, Elvira Immacolata Parrotta,

Embryonic stem cells (ESCs) are defined as stem cells with self-renewing and differentiation capabilities. These unique properties are tightly regulated and controlled by complex genetic and molecular mechanisms, whose understanding is essential for both basic and translational research. A large number of studies have mostly focused on understanding the molecular mechanisms governing pluripotency and differentiation of ESCs, while the regulation of proliferation has received comparably less attention. ...

Tópico(s): Renal and related cancers

2024 - Elsevier BV | Stem Cell Reports

Artigo Acesso aberto Brasil Produção Nacional Revisado por pares

C. N. F. Carvalho, David Rafael Abreu Reyes, Juliana Ferreira Floriano, Stephanie Mishell López Quiroz, Rafael Guilen de Oliveira, Fernanda Cristina Bérgamo Alves, G. A. Garcia, L. F. Iamundo, A. B. M. Magyori, Caroline Baldini Prudêncio, Patrícia de Souza Rossignoli, Cristiane Rodrigues Pedroni, Raghavendra L. S. Hallur, Iracema de Mattos Paranhos Calderon, Angélica Mércia Pascon Barbosa, Marilza Vieira Cunha Rudge, Marilza Vieira Cunha Rudge, Angélica Mércia Pascon Barbosa, Iracema de Mattos Paranhos Calderon, Fátima Pereira de Souza, T Lehana, Carlos F. O. Graeff, Spencer Luíz Marques Payão, Meline Rossetto Kron Rodrigues, Sérgio Luís Felisbino, W. F. Barbosa, G. Bossolan, José Eduardo Corrente, Hélio Rubens de Carvalho Nunes, Joélcio Francisco Abbade, Patrícia de Souza Rossignoli, Cristiane Rodrigues Pedroni, Z. I. Jármy-Di Bella, Silvana Maria de Macêdo Uchôa, Marco Antônio Húngaro Duarte, Edson Assunção Mareco, M. E. Sakalem, Natália Martinho, Diego Girotto Bussaneli, M. I. G. Orlandi, C. Pascon, T. D. Dangió, Cibele Vieira Cunha Rudge, Fernanda Pículo, Giovanni Prata, Raíssa Escandiusi Avramidis, C. N. F. Carvalho, A. B. M. Magyori, G. T. A. Nava, T. D. Caldeirão, R. H. L. Shetty, David Rafael Abreu Reyes, Fernanda Cristina Bérgamo Alves, J. P. C. Marcondes, M.L.S. Takemoto, Caroline Baldini Prudêncio, Fabiane A. Pinheiro, Carlos Izaias Sartorão Filho, S. B. C. V. Quiroz, T. Pascon, Sthefanie K. Nunes, B. B. Catinelli, F. V. D. S. Reis, Rafael Guilen de Oliveira, Sarah Maria Barneze Costa, Mariane de Oliveira Menezes, N. J. Santos, E. M. A. Enriquez, Luiz Takano, A. M. Carr, G. A. Garcia, L. F. Iamundo, H. C. M. Bassin, V. P. Barbosa, M. Jacomin, A. J. B. Silva, I. O. Lourenço, Sá J Marostica, Ícaro Putinhon Caruso, L.‐T. RASMUSSEN, V. K. C. Nogueira, J. T. Ribeiro-Paes, Danielle Cristina Honório França, H. V. M. Bastos, M. L. A. Heliodoro, M. N. Kuroda, H. L. Carvalho, Francielle C. Mosele, M. A. Oliveira, Maria Raynara Pereira Chaves, Eduardo E. Laverde, Bruna Soares de Oliveira, T. C. T. Ciconi,

Tópico(s): Pregnancy-related medical research

2025 - BioMed Central | BioMedical Engineering OnLine

Artigo Acesso aberto Brasil Produção Nacional Revisado por pares

Fabiana Vieira Duarte de Souza Reis, Carlos Izaias Sartorão Filho, Luis Sobrevía, Caroline Baldini Prudêncio, Bruna Bologna, L. F. Iamundo, Adriely Bittencourt Morgenstern Magyori, Luiz Takano, Raissa Escandiussi Avramidis, Rafael Guilen de Oliveira, Marilza Vieira Cunha Rudge, Caroline Baldini Prudêncio, Iracema de Mattos Paranhos Calderon, Fátima Pereira de Souza, T. Lehana, Carlos F. O. Graeff, Cláudia Garcia Magalhães, Roberto Costa, Silvana Andréa Molina Lima, Meline Rossetto Kron Rodrigues, Sérgio Luís Felisbino, W. F. Barbosa, F. J. Campos, G. Bossolan, José Eduardo Corrente, Hélio Rubens de Carvalho Nunes, Joélcio Francisco Abbade, Patrícia de Souza Rossignoli, Cristiane Rodrigues Pedroni, Á. N. Atallah, Z. I. Jármy-Di Bella, Silvana Maria de Macêdo Uchôa, Marco Antônio Húngaro Duarte, Edson Assunção Mareco, M. E. Sakalem, Natália Martinho, Diego Girotto Bussaneli, M. I. G. Orlandi, C. Pascon, T. D. Dangió, Cibele Vieira Cunha Rudge, Fernanda Pículo, Giovanni Prata, C. N. F. Carvalho, A. B. M. Magyori, G. T. A. Nava, T. C. D. Caldeirão, R. H. L. Shetty, David Rafael Abreu Reyes, Fernanda Cristina Bérgamo Alves, J. P. C. Marcondes, M.L.S. Takemoto, Fabiane A. Pinheiro, S. B. C. V. Quiroz, T. Pascon, Sthefanie K. Nunes, B. B. Catinelli, F. V. D. S. Reis, Sarah Maria Barneze Costa, Mariane de Oliveira Menezes, N. J. Santos, E. M. A. Enriquez, A. M. Carr, G. A. Garcia, H. C. M. Bassin, V. P. Barbosa, M. Jacomin, A. J. B. Silva, I. O. Lourenço, Jéssica Maróstica de Sá, Ícaro Putinhon Caruso, L.‐T. RASMUSSEN, V. K. C. Nogueira, J. T. Ribeiro-Paes, Danielle Cristina Honório França, H. V. M. Bastos, M. L. A. Heliodoro, M. N. Kuroda, H. L. Carvalho,

The literature has been evolving to standardize gestational diabetes mellitus (GDM) diagnosis and terminology. The significance of timing in diagnosing hyperglycemia during pregnancy is underlined by evidence that women diagnosed at 24 weeks of gestation or earlier are at a higher risk of developing postpartum prediabetes, but its association with adverse outcomes for the newborn is controversial. We aimed to investigate the association between early-onset GDM and adverse outcomes in newborns and ...

Tópico(s): Birth, Development, and Health

2024 - BioMed Central | Clinical Diabetes and Endocrinology