Antonio Miceli, Egidio Varone, Danyiar Gilmanov, Michele Murzi, Simone Simeoni, Giovanni Concistrè, F Marchi, Marco Solinas, Mattia Glauber,
Background Pulmonary hypertension (PH) is a well-known independent risk factor for mortality and morbidity after cardiac surgery. However, no weight is given to PH in the current guidelines for the management of patients with aortic stenosis (AS) undergoing aortic valve replacement (AVR). The aim of our study was to evaluate the impact of preoperative PH on early and five-year survival in patients with severe AS undergoing isolated AVR. Methods From January 2005 to July 2010, 422 consecutive patients ...
Tópico(s): Cardiovascular Function and Risk Factors
2013 - Elsevier BV | International Journal of Cardiology
E. Burattini, Elsa Cossu, C. Di Maggio, M. Gambaccini, Paola Indovina, M. Marziani, M Pocek, S. Simeoni, Giovanni Simonetti,
PURPOSE: To determine the feasibility of using synchrotron radiation (SR) in diagnostic mammography. MATERIALS AND METHODS: Monochromatic SR of x-ray beams of selected energies of 14-20 keV were used to obtain mammograms of surgically removed breast specimens that contained tumor nodules. For comparison, conventional mammograms of the same specimens were also obtained. RESULTS: The mammograms obtained with SR had higher contrast and better resolution than did traditional mammograms and demonstrated ...
Tópico(s): Medical Imaging Techniques and Applications
1995 - Radiological Society of North America | Radiology
Lisa Monoscalco, Rossella Simeoni, Giovanni Maccioni, Daniele Giansanti,
Cybersecurity is becoming an increasingly important aspect to investigate for the adoption and use of care robots, in term of both patients' safety, and the availability, integrity and privacy of their data. This study focuses on opinions about cybersecurity relevance and related skills for physiotherapists involved in rehabilitation and assistance thanks to the aid of robotics. The goal was to investigate the awareness among insiders about some facets of cybersecurity concerning human-robot interactions. ...
Tópico(s): Robotics and Automated Systems
2022 - Multidisciplinary Digital Publishing Institute | Healthcare
Flavia Grignaffini, Francesco Barbuto, Lorenzo Piazzo, Maurizio Troiano, Patrizio Simeoni, Fabio Mangini, Giovanni Pellacani, Carmen Cantisani, Fabrizio Frezza,
Skin cancer (SC) is one of the most prevalent cancers worldwide. Clinical evaluation of skin lesions is necessary to assess the characteristics of the disease; however, it is limited by long timelines and variety in interpretation. As early and accurate diagnosis of SC is crucial to increase patient survival rates, machine-learning (ML) and deep-learning (DL) approaches have been developed to overcome these issues and support dermatologists. We present a systematic literature review of recent research ...
Tópico(s): AI in cancer detection
2022 - Multidisciplinary Digital Publishing Institute | Algorithms
Umberto Simeoni, Giovanni Calderoni, Umberto Tessari, E. Mazzini,
A study was carried out on the coast applying an extension of the System Theory methodology, investigating the relationships which exist between agents and processes in the beach-foredune system. For this purpose 14 parameters were chosen which are believed to define the system: 4 to describe the meteorogical and oceanographic characteristics, 1 for the evolutionary ones, 2 for the sedimentological ones, 5 for the morphological ones and 2 for the biological ones. Their interaction intensity and ...
Tópico(s): Coastal and Marine Management
1999 - Coastal Education and Research Foundation | Journal of Coastal Research
Rossella Simeoni, Giovanni Maccioni, Daniele Giansanti,
The vaccination against the COVID-19, finally available, has the potential to represent an important defence against the pandemic. The identification of both obstacles and tools to combat them are, at this moment, of strategic importance. Previous experiences on vaccinations have shown solutions and paths to take, also based on the behavioural sciences. The objective of the opinion is to face how mobile technology can help us both to fight these problems and to optimize the vaccination process. ...
Tópico(s): COVID-19 epidemiological studies
2021 - Multidisciplinary Digital Publishing Institute | Healthcare
Francesca Del Signore, Stefania De Dominicis, Giovanni Mastromatteo, Francesco Simeoni, P. A. Scapolo, Roberto Tamburro, Massimo Vignoli,
Abstract Shear wave elastography (SWE) is a feasible and newly developed ultrasonographic technique which is able to assess elasticity of tissues. The aim of this work was to assess the feasibility of SWE on the normal canine common calcaneal tendon (CCT) evaluating the intra-operator repeatability and reproducibility of single measurements and stiffness of different anatomic CCT portions was examined. Tendons were first evaluated with B-mode ultrasound with a linear probe 8.5 to 10 MHz in longitudinal ...
Tópico(s): Orthopedic Surgery and Rehabilitation
2020 - Schattauer Verlag | Veterinary and Comparative Orthopaedics and Traumatology
Francesco Simeoni, Francesca Del Signore, Giovanni Aste, Paolo Bargellini, Giuseppe Rubini, Rossella Terragni, Roberto Tamburro, Ilaria Falerno, Francesco de Pasquale, Marco Russo, Massimo Vignoli,
Canine gastric disorders are common in veterinary clinical practice and among these neoplasms require rapid identification and characterization. Standard ultrasound (US) is the imaging modality of choice for gastric wall assessment. The aim of this prospective study is to describe the specific B-mode and contrast enhanced US (CEUS) features of normal, inflammatory, and neoplastic gastric wall in dogs. B-mode US and CEUS of the stomach were performed in anesthetized dogs with or without gastric disorders. ...
Tópico(s): Salivary Gland Tumors Diagnosis and Treatment
2021 - Multidisciplinary Digital Publishing Institute | Animals
Marco Solinas, Giacomo Bianchi, Francesca Chiaramonti, Rafik Margaryan, Enkel Kallushi, Tommaso Gasbarri, Filippo Santarelli, Michele Murzi, Pierandrea Farneti, Alessandro Leone, Simone Simeoni, Egidio Varone, F Marchi, Mattia Glauber, Giovanni Concistrè,
Background: A minimally invasive approach (MIA) reduces mortality and morbidity in patients referred for aortic valve replacement (AVR). Sutureless technology facilitates a MIA. We describe our experience with the sutureless Perceval (LivaNova, Italy) aortic bioprosthesis through a right anterior mini-thoracotomy (RAMT) approach. Methods: Between March 2011 and October 2019, 1,049 patients underwent AVR with Perceval bioprosthesis. Five hundred and three patients (48%) were operated through a RAMT approach ...
Tópico(s): Aortic Disease and Treatment Approaches
2020 - AME Publishing Company | Annals of Cardiothoracic Surgery
Giuseppina D’Onofrio, Mariadelina Simeoni, Paolo Rizza, Mariarita Caroleo, Maria Capria, Giovanni Mazzitello, Tiziana Sacco, Elena Mazzuca, Maria Teresa Panzino, Annamaria Cerantonio, Cristina Segura‐García, Michele Andreucci, Pasquale De Fazio, Giorgio Fuíano,
Rational: Our aim was to investigate the quality of life (QoL) in 103 patients undergoing chronic hemodialysis (HD) in an integrated assessment of clinical, personological, and adaptation parameters, also in a non-urban context.Objectives: We collected data from all chronic HD patients attending four HD units. Clinical status was assessed by Kidney Disease Outcomes Quality Initiative (KDOQI) guidelines and by Age-adjusted Charlson Comorbidity Index (ACCI). Patients completed the following questionnaires: ...
Tópico(s): Restless Legs Syndrome Research
2016 - Taylor & Francis | Renal Failure
Antonello Mai, Marino Artico, Dante Rotili, Domenico Tarantino, Imma Clotet‐Codina, Mercedes Armand‐Ugón, Rino Ragno, Silvia Simeoni, Gianluca Sbardella, Maxim B. Nawrozkij, Alberta Samuele, Giovanni Maga, José A. Esté,
Following the disclosure of dihydro-alkoxy-, dihydro-alkylthio-, and dihydro-alkylamino-benzyl-oxopyrimidines (DABOs, S-DABOs, and NH-DABOs) as potent and selective anti-HIV-1 agents belonging to the non-nucleoside reverse transcriptase inhibitor (NNRTI) class, we report here the synthesis and biological evaluation of a novel series of DABOs bearing a N,N-disubstituted amino group or a cyclic amine at the pyrimidine-C2 position, a hydrogen atom or a small alkyl group at C5 and/or at the benzylic position, ...
Tópico(s): Tuberculosis Research and Epidemiology
2007 - American Chemical Society | Journal of Medicinal Chemistry
Laura Manuto, Marco Grazioli, Andrea Spitaleri, Paolo Fontana, Luca Bianco, Luigi Bertolotti, Martina Bado, Giorgia Mazzotti, Federico Bianca, Francesco Onelia, Giovanni Lorenzin, Fabio Simeoni, Dejan Lazarević, Elisa Franchin, Claudia Del Vecchio, Ilaria Dorigatti, Giovanni Tonon, Daniela María Cirillo, Enrico Lavezzo, Andrea Crisanti, Stefano Toppo,
In February 2020, the municipality of Vo’, a small town near Padua (Italy) was quarantined due to the first coronavirus disease 19 (COVID-19)-related death detected in Italy. To investigate the viral prevalence and clinical features, the entire population was swab tested in two sequential surveys. Here we report the analysis of 87 viral genomes, which revealed that the unique ancestor haplotype introduced in Vo’ belongs to lineage B, carrying the mutations G11083T and G26144T. The viral sequences ...
Tópico(s): COVID-19 epidemiological studies
2022 - Multidisciplinary Digital Publishing Institute | Viruses
Michelangela Barbieri, Paolo Chiodini, Piergiacomo Di Gennaro, Gaye Hafez, Sophie Liabeuf, Jolanta Małyszko, Laila‐Yasmin Mani, Francesco Mattace‐Raso, Marion Pépin, Norberto Perico, Mariadelina Simeoni, Carmine Zoccali, Giovanni Tortorella, Annalisa Capuano, Giuseppe Remuzzi, Giovambattista Capasso, Giuseppe Paolisso,
Patients with chronic kidney disease (CKD) often experience mild cognitive impairment and other neurocognitive disorders. Studies have shown that erythropoietin (EPO) and its receptor have neuroprotective effects in cell and animal models of nervous system disorders. Recombinant human EPO (rHuEPO), commonly used to treat anemia in CKD patients, could be a neuroprotective agent. In this systematic review, we aimed to assess the published studies investigating the cognitive benefits of rHuEPO treatment ...
Tópico(s): Dialysis and Renal Disease Management
2024 - Elsevier BV | Pharmacological Research
Valérie A. Luyckx, Norberto Perico, Marco Somaschini, Dario Manfellotto, Herbert Valensise, Irene Cetin, Umberto Siméoni, Karel Allegaert, Bjørn Egil Vikse, Eric A.P. Steegers, Dwomoa Adu, Giovanni Montini, Giuseppe Remuzzi, Barry M. Brenner, Dwomoa Adu, Karel Allegaert, Chiara Benedetto, Barry M. Brenner, Irene Cetin, Jennifer R. Charlton, Robert L. Chevalier, Monica Cortinovis, Rosario D’Anna, Johannes J. Duvekot, Joaquín Escribano, Vassilios Fanos, E. Ferrazzi, T. Frusca, Richard J. Glassock, Wilfried Gyselaers, Valérie A. Luyckx, Dario Manfellotto, Federico Mecacci, Giovanni Montini, Clive Osmond, Norberto Perico, Luca A. Ramenghi, Giuseppe Remuzzi, Paola Romagnani, Antonio Santoro, Umberto Siméoni, Marco Somaschini, Eric A.P. Steegers, Herbert Valensise, Bjørn Egil Vikse,
Tópico(s): Child Nutrition and Water Access
2017 - Elsevier BV | The Lancet
Produção Nacional
Revisado por pares
Alexandre Borin, Laís D. Coimbra, Karina Bispo-dos-Santos, Fabrício F. Naciuk, Marina Alves Fontoura, Camila L. Simeoni, Giovanni Freitas Gomes, Mariene R. Amorim, Humberto Doriguêtto Gravina, Jacqueline Farinha Shimizu, Amanda Stephane Cruz dos Passos, Isadora M. de Oliveira, Ana Carolina de Carvalho, Alisson C. Cardoso, Pierina Lorencini Parise, Daniel A. Toledo-Teixeira, Giuliana E. Sotorilli, Gabriela Félix Persinoti, Ingra Morales Claro, Éster Cerdeira Sabino, Marcos Rodrigo Alborghetti, Silvana A. Rocco, Kleber G. Franchini, William Marciel de Souza, Paulo Sérgio Lopes de Oliveira, Thiago M. Cunha, Fabiana Granja, José Luiz Proença‐Módena, Daniela Barretto Barbosa Trivella, Marjorie Bruder, Artur T. Cordeiro, Rafael Elias Marques,
The ongoing COVID-19 pandemic caused a significant loss of human lives and a worldwide decline in quality of life. Treatment of COVID-19 patients is challenging, and specific treatments to reduce COVID-19 aggravation and mortality are still necessary. Here, we describe the discovery of a novel class of epiandrosterone steroidal compounds with cationic amphiphilic properties that present antiviral activity against SARS-CoV-2 in the low micromolar range. Compounds were identified in screening campaigns ...
Tópico(s): Influenza Virus Research Studies
2022 - Taylor & Francis | Virulence
Francesco Simeoni, Francesca Del Signore, Rossella Terragni, Roberto Tamburro, Giovanni Aste, Massimo Vignoli,
Gastrointestinal tract tumours in dogs and cats are characterized by non-specific clinical presentation and laboratory abnormalities, but require fast identification, characterization and staging. Imaging techniques play a key role in the diagnostic process of these diseases in routine veterinary practice. Survey and contrast radiography may indicate primary or secondary signs of gastric or intestinal neoplasia such as a wall mass, functional alterations and stenosis points, but they have low sensibility ...
Tópico(s): Cancer Research and Treatments
2020 - | American Journal of Animal and Veterinary Sciences
Giuseppe Arbia, Giovanni Lafratta, Carla Simeoni,
A spatial sampling strategy is proposed for monitoring the exceedances of soil pollutants over a given regulatory threshold in a discretized three-dimensional (3-D) portion of space. In each site of the study area, an indicator variable is defined assuming a value of 1 if the threshold is exceeded and 0 otherwise. The spatial distribution of such variables represents an expected probability map of exceeding the threshold, characterized by a certain degree of spatial dependence. The first and second ...
Tópico(s): Economic and Environmental Valuation
2007 - Elsevier BV | Computational Statistics & Data Analysis
S. Simeoni, Roberto Biselli, Raffaele D’Amelio, Bianca Rocca, Stefano Lattanzio, Luciana Mucci, Giovanni Davı̀, Francesca Romana Patacchioli,
Few studies have assessed the effects of stress on in vivo platelet activation. In the present study, hypobaric hypoxia induced by rapid decompression during high-altitude simulated flight in a hypobaric chamber was used to evaluate the effects of environmental stress on salivary cortisol and urinary thromboxane metabolite (TXM) excretion, a noninvasive marker of in vivo platelet function. Twenty-one male aviators (mean ± SD age = 36 ± 7 years) experiencing hypoxia by removing their oxygen mask for 4–5 ...
Tópico(s): Heart Rate Variability and Autonomic Control
2011 - Informa | Stress
Paolo Di Giorgio, Giovanni Di Ilio, Gabriele Scarpati, Giovanni Erme, Elio Simeoni, Elio Jannelli,
Hydrogen-powered vehicles are emerging as a key source for a clean and sustainable mobility scenario. In particular, hydrogen technologies have a great potential for light mobility in urban areas, where traffic congestion may cause very high levels of local pollution. In this context, hybrid fuel cell/battery vehicles represent a promising solution, since they allow for extended driving range and short recharge time, which are two of the major concerns related to electric propulsion, in general. ...
Tópico(s): Advanced Battery Technologies Research
2022 - EDP Sciences | E3S Web of Conferences
Giovanni Di Cristina, Nicholas S. Skowronski, Albert Simeoni, Ali S. Rangwala, Seong-kyun Im,
The forced flow driven flame spread behavior along an array of discrete wooden fuel elements was experimentally investigated, which could be an important step to understanding the flow-flame interactions that govern fire spread. Fuel arrays with five different spacings (0.75, 0.875. 1.00, 1.125, and 1.25 cm) were subject to flow speeds ranging from 2.2 to 4.3 m/s at approximately 0.2 m/s intervals. For spacing-flow speed conditions tested in the current study, the flame spread behavior was categorized ...
Tópico(s): Wind and Air Flow Studies
2020 - Elsevier BV | Proceedings of the Combustion Institute
Giovanni Di Cristina, Nicholas S. Skowronski, Albert Simeoni, Ali S. Rangwala, Seong-kyun Im,
A stagnation-point flow model based in part on the mass transfer B-number was adapted to approximate the heat flux and time to ignition of dowel arrays subject to forced convection flame spread. Previous work on forced flow flame spread along a dowel array has characterized the existence of discretized flame behavior. In deployment-scale wildland fire models, small fuels are smaller than the grid resolution. Sub-grid modeling then relies on empirical relationships, such as Nusselt number–Reynolds ...
Tópico(s): Wind and Air Flow Studies
2021 - Elsevier BV | Combustion and Flame
Giovanni Di Cristina, Shijin P. Kozhumal, Albert Simeoni, Nicholas S. Skowronski, Ali S. Rangwala, Seong-kyun Im,
The effects of freestream flow on fire spread behaviors of a discrete wooden fuel array were studied. The spacing between fuel elements was varied, and the flame spread behavior under 1, 2, and 3 m/s forced flow velocities was investigated. The fastest spread rate was not observed for the smallest spacing. Furthermore, increasing spacing did not necessarily lead to a slower spread, as seen with the flame spread along the 0.75 cm spaced array which was as fast or faster than the 0.5 cm spacing condition. ...
Tópico(s): Wind and Air Flow Studies
2020 - Elsevier BV | Fire Safety Journal
Giovanni Cappelletti, Diego Caratelli, Renato Cicchetti, Massimiliano Simeoni,
A class of printed antipodal drop-shaped dipole antennas for wideband wireless communication systems is presented. A suitable shaping of the feeding lines and radiating arms is adopted to achieve an operating bandwidth larger than 10 GHz useful to meet the requirements of several wireless communication standards. A thin, low permittivity dielectric substrate is used to reduce the excitation of surface waves which are responsible for a degradation of the radiative characteristics. The proposed antenna ...
Tópico(s): Microwave Engineering and Waveguides
2011 - IEEE Antennas & Propagation Society | IEEE Transactions on Antennas and Propagation
Francesco Collivignarelli, Roberto Tamburro, Giovanni Aste, Ilaria Falerno, Francesca Del Signore, Francesco Simeoni, Michail Patsikas, Jacopo Gianfelici, Rossella Terragni, Valeria Attorri, Augusto Carluccio, Massimo Vignoli,
Mammary gland tumors are the most common canine neoplasms. They account for 25–50% of all tumors diagnosed in bitches. Metastases and recurrences develop in about 35–70% of bitches following excision. The presence of regional lymph node metastases is a relevant factor affecting prognosis and treatment in cases of mammary gland tumors. The sentinel lymph node (SLN) is the first lymph node (or nodes) in the regional lymphatic basin that receives lymphatic flow from the primary neoplasm. The aim of this ...
Tópico(s): Infectious Diseases and Mycology
2021 - Multidisciplinary Digital Publishing Institute | Animals
Franck Schürhoff, Giovanni Stévanin, Yvon Trottier, Frank Bellivier, Marie Christine Mouren-Siméoni, Alexis Brice, Marion Leboyer,
Genetic factors are of major aetiological importance in bipolar disorder and schizophrenia. The exact mode of inheritance is unknown, but recent arguments in favor of genetic anticipation in those two disorders suggest that dynamic mutations could be involved. Using a new antibody, we thus explored the implication of large expanded polyglutamine tract, in a sample of very early onset schizophrenic and bipolar patients. No evidence for a specific protein with polyglutamine expansion was found in ...
Tópico(s): Neurological disorders and treatments
1997 - Elsevier BV | Psychiatry Research
Mario Giovanni Terzano, Liborio Parrino, Maria Cristina Spaggiari, Roberta Barusi, S. Simeoni,
Summary: Twenty epileptic patients (10 male and 10 female) were polygraphically recorded during nocturnal sleep. Ten subjects, with a wide age range, were affected by focal lesional epilepsy, and 10 were children affected by benign epilepsy with rolandic spikes (BERS). In five cases a bihemispheric expression of the focal lesional bursts emerged occasionally during the night recordings. The behavior of interictal electroencephalographic (EEG) paroxysms were analyzed with respect to the two arousal ...
Tópico(s): Sleep and Wakefulness Research
1991 - Wiley | Epilepsia
Michele Equestre, Cinzia Marcantonio, Nadia Marascio, Federica Centofanti, Antonio Martina, Matteo Simeoni, Elisabetta Suffredini, Giuseppina La Rosa, Giusy Bonanno Ferraro, Pamela Mancini, Carolina Veneri, Giovanni Matera, Angela Quirino, Angela Costantino, Stefania Taffon, Elena Tritarelli, Carmelo Campanella, Giulio Pisani, Roberto Nisini, Enea Spada, Paola Verde, Anna Rita Ciccaglione, Roberto Bruni,
We investigated SARS-CoV-2 variants circulating, from November 2020 to March 2022, among military and civilian personnel at an Air Force airport in Italy in order to classify viral isolates in a potential hotspot for virus spread. Positive samples were subjected to Next-Generation Sequencing (NGS) of the whole viral genome and Sanger sequencing of the spike coding region. Phylogenetic analysis classified viral isolates and traced their evolutionary relationships. Clusters were identified using 70% ...
Tópico(s): vaccines and immunoinformatics approaches
2023 - Multidisciplinary Digital Publishing Institute | Microorganisms
Giovanni Bosco, Lucia Simeoni, Mattia Dalpiaz,
This study aims to understand in what manner a change from grassland to irrigated apple orchards can produce significant changes on the atmospheric soil–water exchange and in turn on the pore water pressure distribution with depth. Both changes may affect slope stability, as a result of infiltration, a rising water table and modified suction profiles. Pore pressure distributions were determined over an average of a 1-year period. The water balance considers infiltration due to precipitation and ...
Tópico(s): Landslides and related hazards
2016 - ICE Publishing | Environmental Geotechnics
... some bishops, the prefect of Propaganda Fide, Cardinal Giovanni Simeoni, had asked the Archbishop of Baltimore, Cardinal James ...
Tópico(s): Catholicism and Religious Studies
2008 - The Catholic University of America Press | The Jurist/The jurist
Rachel M. Gittelman, Enrico Lavezzo, Thomas M. Snyder, H. Jabran Zahid, Cara L. Carty, Rebecca Elyanow, Sudeb C. Dalai, Ilan R. Kirsch, Lance Baldo, Laura Manuto, Elisa Franchin, Claudia Del Vecchio, Monia Pacenti, Caterina Boldrin, Margherita Cattai, Francesca Saluzzo, Andrea Padoan, Mario Plebani, Fabio Simeoni, Jessica Bordini, Nicola Ivan Lorè, Dejan Lazarević, Daniela María Cirillo, Paolo Ghia, Stefano Toppo, Jonathan M. Carlson, Harlan Robins, Andrea Crisanti, Giovanni Tonon,
T cells play a prominent role in orchestrating the immune response to viral diseases, but their role in the clinical presentation and subsequent immunity to SARS-CoV-2 infection remains poorly understood. As part of a population-based survey of the municipality of Vo', Italy, conducted after the initial SARS-CoV-2 outbreak, we sampled the T cell receptor (TCR) repertoires of the population 2 months after the initial PCR survey and followed up positive cases 9 and 15 months later. At 2 months, we ...
Tópico(s): vaccines and immunoinformatics approaches
2022 - American Society for Clinical Investigation | JCI Insight