Katherine Esposito, Miryam Ciotola, Francesco Giugliano, Maria Ida Maiorino, Riccardo Autorino, Marco De Sio, Giovanni Giugliano, Gianfranco Nicoletti, Francesco D’Andrea, Dario Giugliano,
Tópico(s): Urinary Bladder and Prostate Research
2008 - Elsevier BV | The Journal of Sexual Medicine
Katherine Esposito, Miryam Ciotola, F Giugliano, Marco De Sio, Giovanni Giugliano, Massimo D’Armiento, Dario Giugliano,
Men with the metabolic syndrome demonstrate an increased prevalence of erectile dysfunction (ED). In the present study, we tested the effect of a Mediterranean-style diet on ED in men with the metabolic syndrome. Men were identified in our database of subjects participating in controlled trials evaluating the effect of lifestyle changes and were included if they had a diagnosis of ED associated with a diagnosis of metabolic syndrome, complete follow-up in the study trial, and intervention focused ...
Tópico(s): Eating Disorders and Behaviors
2006 - Springer Nature | International Journal of Impotence Research
M Polito, Daniele Minardi, Alberto Recchioni, I Giannulis, Giuseppina De Sio, Giovanni Muzzonigro,
BACKGROUND Serum TPS (tissue polypeptide-specific antigen) has been observed to be characteristic of carcinoma proliferation, and increased levels of TPS seem to be closely related to tumor progression. In this study we wanted to evaluate the importance of the tumor-marker TPS in the diagnosis and follow-up of patients with prostatic carcinoma, and to compare it with prostate-specific antigen (PSA). METHODS We considered 39 patients with clinically confined disease, who underwent neoadjuvant hormonal ...
Tópico(s): Urologic and reproductive health conditions
1997 - Wiley | The Prostate
Antonio Vitarelli, Silvia Lai, Maria Teresa Petrucci, Carlo Gaudio, Lidia Capotosto, Enrico Mangieri, Serafino Ricci, Giuseppe Germanò, Simone De Sio, Giovanni Truscelli, Federico Vozella, Mario Pergolini, M. Giordano,
Abstract Background Given that in patients with cardiac amyloidosis (CA), deposition of amyloid protein is not restricted to the left ventricular (LV) myocardium, it can be hypothesized that the diagnostic value of deformation mechanics would be enhanced by considering right ventricular (RV) strain measures. The aim of the present study was to examine the potential utility of left ventricular (LV) and right ventricular (RV) deformation and rotational parameters derived from three-dimensional speckle-tracking ...
Tópico(s): Cardiomyopathy and Myosin Studies
2018 - Elsevier BV | International Journal of Cardiology
V. Tioukov, A. Alexandrov, C. Bozza, L. Consiglio, N. D’Ambrosio, G. De Lellis, Chiara De Sio, Flora Giudicepietro, Giovanni Macedonio, Seigo Miyamoto, Ryuichi Nishiyama, M. Orazi, Rosario Peluso, A. Sheshukov, C. Sirignano, Simona Maria Stellacci, Paolo Strolin, Hiroyuki Tanaka,
Abstract Muography consists in observing the differential absorption of muons – elementary particles produced through cosmic-ray interactions in the Earth atmosphere – going through the volcano and can attain a spatial resolution of tens of meters. We present here the first experiment of nuclear emulsion muography at the Stromboli volcano. Muons have been recorded during a period of five months by a detector of 0.96 m 2 area. The emulsion films were prepared at the Gran Sasso underground laboratory ...
Tópico(s): Astrophysics and Cosmic Phenomena
2019 - Nature Portfolio | Scientific Reports
Giuseppe Quero, Nicolò Pecorelli, Salvatore Paiella, Claudio Fiorillo, Maria Chiara Petrone, Giovanni Capretti, Vito Laterza, Davide De Sio, Roberta Menghi, Emanuele F. Kauffmann, Sara Nobile, Giovanni Butturini, Giovanni Ferrari, Fausto Rosa, Andrea Coratti, Riccardo Casadei, Vincenzo Mazzaferro, Ugo Boggi, Alessandro Zerbi, Roberto Salvia, Massimo Falconi, Sergio Alfieri,
With the prolongation of life expectancy, an increasing number of elderly patients are evaluated for pancreatic surgery. However, the influence of increasing age on outcomes after pancreaticoduodenectomy (PD) is still unclear, especially in octogenarians. Aim of this study is to evaluate the perioperative characteristics and outcomes of octogenarians undergoing PD.Data for 812 patients undergoing PD between 2019 and 2020 in 10 referral centers in Italy were reviewed. Patients aged 80 years or older ...
Tópico(s): Pancreatitis Pathology and Treatment
2021 - Elsevier BV | Surgical Oncology
Cristina Satriano, Giovanni Marletta, B. Kasemo,
Abstract Atomically flat films of poly(hydroxymethyl)siloxane (PHMS) were modified at surfaces by oxygen‐plasma treatments and characterized by several surface sensitive techniques. The purpose was to develop well‐characterized films with SiO x surface properties for various applications. The unmodified and plasma‐treated PHMS films were investigated by angular resolved XPS (ARXPS in situ in the plasma equipment), Fourier transformed infrared spectroscopy (FTIR), atomic force microscopy (AFM), and contact ...
Tópico(s): Diamond and Carbon-based Materials Research
2008 - Wiley | Surface and Interface Analysis
Giovanni Gilardi, Luciano De Sio, Romeo Beccherelli, Rita Asquini, Antonio d’Alessandro, Cesare Umeton,
We report on the investigation and characterization of an optically tunable filtering effect, observed in a waveguide grating made of alternated strips of photocurable polymer and a mixture of azo-dye-doped liquid crystal. The grating is sandwiched between two borosilicate glasses, one of which includes an ion-exchanged channel waveguide, which confines the optical signal to be filtered. Exposure to a low power visible light beam modifies the azo-dye molecular configuration, thus allowing the filtered ...
Tópico(s): Photonic Crystals and Applications
2011 - Optica Publishing Group | Optics Letters
Renato Franco, Silvia Zappavigna, Vincenzo Gigantino, Amalia Luce, Monica Cantile, Margherita Cerrone, Gaetano Facchini, Sisto Perdonà, Sandro Pignata, Giuseppe Di Lorenzo, Sergio Chieffi, Giovanni Vitale, Marco De Sio, Alessandro Sgambato, Gerardo Botti, Ali Munaim Yousif, Ettore Novellino, Paolo Grieco, Michele Caraglia,
Non Muscle Invasive Bladder Transitional Cancer (NMIBC) and Muscle Invasive Bladder Transitional Cancer (MIBC)/invasive have different gene profile and clinical course. NMIBC prognosis is not completely predictable, since the relapse rate is higher than 20%, even in the form of MIBC. The aim of this study is to evaluate if UTR expression can discriminate between NMIBC and MIBC and predict the risk of relapses in NMIBCs. We have investigated upon urotensin-II (UII) receptor (UTR) expression in vivo in ...
Tópico(s): Hormonal Regulation and Hypertension
2014 - BioMed Central | Journal of Experimental & Clinical Cancer Research
Simona Concilio, Valeria Bugatti, H. C. Neitzert, Giovanni Landi, Antonietta De Sio, Jürgen Parisi, Stefano Piotto, Pio Iannelli,
Tópico(s): Organic Light-Emitting Diodes Research
2014 - Elsevier BV | Thin Solid Films
C. Barone, Giovanni Landi, Antonietta De Sio, H. C. Neitzert, S. Pagano,
Tópico(s): Force Microscopy Techniques and Applications
2013 - Elsevier BV | Solar Energy Materials and Solar Cells
Alexa Guglielmelli, Paolo Rosa, Marco Contardi, Mirko Prato, Giorgio Mangino, Selenia Miglietta, Vincenzo Petrozza, R. Pani, Antonella Calogero, Athanassia Athanassiou, Giovanni Perotto, Luciano De Sio,
Aim: To realize and characterize a new generation of keratin-coated gold nanoparticles (Ker-AuNPs) as highly efficient photosensitive nanosized therapeutics for plasmonic photothermal (PPT) therapy. Materials & methods: The chemical, physical, morphological and photothermal properties of Ker-AuNPs are investigated using dynamic light scattering, ζ-potential, UV-Visible, Fourier transform infrared spectroscopy, x-ray photoelectron spectroscopy, transmission electron microscopy and high-resolution thermography. ...
Tópico(s): Nanoplatforms for cancer theranostics
2021 - Future Medicine | Nanomedicine
Viviana Frantellizzi, Vanessa Verrina, Clelia Raso, Mariano Pontico, Francesca Petronella, V. Bertana, Alberto Ballesio, Simone Luigi Marasso, Selenia Miglietta, Paolo Rosa, Sofia Scibetta, Vincenzo Petrozza, Maria Silvia De Feo, Giuseppe De Vincentis, Antonella Calogero, R. Pani, Giovanni Perotto, Luciano De Sio,
Biocompatible gold nanoparticles (AuNPs) are particularly interesting for photo-thermal therapy (PTT) of cancer treatment because of their ability to convert light into heating efficiently. Nevertheless, the random accumulation of AuNPs in tissues, mainly determined by their retention time in the bloodstream, is one of the main limiting factors for their use in PTT applications. For this reason, efficient targeting and monitoring of AuNPs in the selected tissues is of paramount importance. This manuscript ...
Tópico(s): Gold and Silver Nanoparticles Synthesis and Applications
2022 - Elsevier BV | Materials Today Advances
Giuseppe La Torre, Alberto Firenze, Corrado Colaprico, Eleonora Ricci, Luciano Pio Di Gioia, Dorotea Serò, G Perri, Manuela Soncin, Dario Cremonesi, Nadia De Camillis, Sara Guidolin, Giulia Evangelista, Mattia Marte, Nicola Giovanni Fedele, Simone De Sio, Alice Mannocci, Sabina Sernia, Silvio Brusaferro,
This cross-sectional study aims to evaluate the prevalence and socio-demographic factors associated with workplace bullying, sexual harassment and racial harassment among Italian health workers.We recruited 3129 participants using an online Italian translation of the 'Workplace Violence in the Health Sector Country Case Studies Research Instruments Survey' (WVHS) questionnaire. Data were analyzed with univariate (chi-square) and multivariate (multiple logistic regression) analysis.Univariate analysis ...
Tópico(s): Healthcare professionals’ stress and burnout
2022 - Multidisciplinary Digital Publishing Institute | International Journal of Environmental Research and Public Health
Savio Domenico Pandolfo, Francesco Del Giudice, Benjamin I. Chung, Celeste Manfredi, Marco De Sio, Rocco Damiano, Edward E. Cherullo, Cosimo De Nunzio, Giovanni Cacciamani, Luca Cindolo, Francesco Porpiglia, Vincenzo Mirone, Ciro Imbimbo, Riccardo Autorino, Fabio Crocerossa,
Tópico(s): Urological Disorders and Treatments
2022 - Springer Nature | Prostate Cancer and Prostatic Diseases
Produção Nacional
Revisado por pares
Federica Zito Marino, Rosalaura Sabetta, Francesca Pagliuca, Matteo Brunelli, Gabriella Aquino, Sisto Perdonà, Gerardo Botti, Gaetano Facchini, Francesco Fiorentino, Giovanni Di Lauro, Marco De Sio, Ferdinando De Vita, Giorgio Toni, Rodolfo Borges dos Reis, Luciano Neder, Renato Franco,
Abstract Background The high-risk human papillomavirus (HPV) infection represents one of the main etiologic pathways of penile carcinogenesis in approximately 30–50 % of cases. Several techniques for the detection of HPV are currently available including Polymerase chain reaction-based techniques, DNA and RNA in situ hybridization (ISH), p16 immunohistochemistry (IHC). The multiplex HPV RNA ISH/p16 IHC is a novel technique for the simultaneous detection of HPV E6/E7 transcripts and p16INK4a overexpression ...
Tópico(s): Urologic and reproductive health conditions
2021 - BioMed Central | Infectious Agents and Cancer
Produção Nacional
Layla Martin‐Samos, Giovanni Bussi, Alice Ruini, Elisa Molinari, Marília Caldas,
We present a first-principles systematic study of the electronic structure of ${\text{SiO}}_{2}$ including the crystalline polymorphs $\ensuremath{\alpha}$ quartz and $\ensuremath{\beta}$ cristobalite, and different types of disorder leading to the amorphous phase. We start from calculations within density functional theory and proceed to more sophisticated quasiparticle calculations according to the $GW$ scheme. Our results show that different origins of disorder have also different impact on atomic and ...
Tópico(s): Advanced Condensed Matter Physics
2010 - American Physical Society | Physical Review B
Gianfranco Ulian, Giovanni Valdrè,
In this work, we modeled the structure, the compressional behavior and the physical properties of topaz over six different fluorine contents and a wide range of pressure, using a quantum mechanical approach based on periodic boundary conditions. We adopted the density functional theory using the B3LYP functional and all-electron Gaussian-type orbitals basis sets. An atomic level description of the athermal (T = 0 K) pressure-induced structural modification of topaz is provided. From the compression ...
Tópico(s): Archaeology and Rock Art Studies
2017 - Mineralogical Society of America | American Mineralogist
F. Della Valle, Giovanni Comelli, Franco Zanini, R. Rosei, G. Paolucci,
We compare transitions observed in photoabsorption spectra above the oxygen and nitrogen K edges in several compounds and chemisorption systems with transitions excited by the process of electron-energy loss detected in the reflection mode. We find few but significant discrepancies between the two, mainly attributable to quadrupole transitions and double inelastic scattering in the electron-energy-loss spectra. The problem of the extraction of structural information from the measurements is considered.
Tópico(s): Analytical Chemistry and Sensors
1988 - American Physical Society | Physical review. B, Condensed matter
Produção Nacional
Revisado por pares
Layla Martin‐Samos, Giovanni Bussi, Alice Ruini, Elisa Molinari, Marília Caldas,
Abstract We present the first‐principle electronic structure calculation on an amorphous material including many‐body corrections within the GW approximation. We show that the inclusion of the local field effects in the exchange–correlation potential is crucial to quantitatively describe amorphous systems and defect states. We show that the mobility gap of amorphous silica coincides with the band gap of quartz, contrary to the traditional picture and the densityfunctional theory results.
Tópico(s): Advanced Condensed Matter Physics
2010 - Wiley | physica status solidi (b)
Modesto Carli, Andrea Ferrari, Adrian Mattke, Ilaria Zanetti, Michela Casanova, Gianni Bisogno, Giovanni Cecchetto, Rita Alaggio, Luigi De Sio, E. Koscielniak, Guido Sotti, J. Treuner,
Purpose To assess the value of chemotherapy and radiotherapy in children with malignant peripheral nerve sheath tumors (MPNSTs) and to identify risk factors associated with outcome. Patients and Methods A total of 167 untreated eligible patients enrolled onto the Italian and German studies between 1975 and 1998 entered this analysis. Seventeen percent of patients had neurofibromatosis type 1 (NF1). Chemotherapy was administered to 74% of patients; radiotherapy was administered to 38% of patients. ...
Tópico(s): Soft tissue tumors and treatment
2005 - Lippincott Williams & Wilkins | Journal of Clinical Oncology
Giovanni Landi, C. Barone, Antonietta De Sio, S. Pagano, H. C. Neitzert,
A detailed electric noise investigation of polymer:fullerene solar cells, at 300 K under dark conditions, is reported. The experimental noise results are interpreted in terms of a model taking into account the device capacitance and recombination resistance. Relevant parameters of the solar cells can be computed through fluctuation spectroscopy, and the results have been compared with those obtained by alternative techniques. After a thermal treatment at 340 K, a modification of the voltage-spectral ...
Tópico(s): Semiconductor materials and interfaces
2013 - American Institute of Physics | Applied Physics Letters
Giovanni Deb, Alessandro Jenkner, Luigi De Sio, Renata Boldrini, C. Bosman, Nicola Standoli, Alberto Donfrancesco,
A two-month-old infant developed a vascular tumor of the right flank which upon biopsy proved to be a spindle cell hemangioendothelioma. The increased capillary bed characterizing the neoplasm caused a severe thrombocytopenia together with a consumption coagulopathy (Kasabach-Merritt syndrome). The patient, who was dependent on platelet transfusions, improved quickly after interferon alpha-2a was given at the dosage of 3,000,000 U/m2, with resolution of the Kasabach-Merritt syndrome after three weeks ...
Tópico(s): Tuberous Sclerosis Complex Research
1997 - Alan R. Liss, Inc. | Medical and Pediatric Oncology
Giovanna Palermo, Luca Barberi, Giovanni Perotto, Roberto Caputo, Luciano De Sio, Cesare Umeton, Fiorenzo G. Omenetto,
The use of biomaterials as optical components has recently attracted attention because of their ease of functionalization and fabrication, along with their potential use when integrated with biological materials. We present here an observation of the optical properties of a silk-azobenzene material (Azosilk) and demonstrate the operation of an Azosilk/PDMS composite structure that serves as a conformable and switchable optical diffractive structure. Characterization of thermal and isomeric properties ...
Tópico(s): Advanced Materials and Mechanics
2017 - American Chemical Society | ACS Applied Materials & Interfaces
Massimiliano Creta, Nicola Longo, Davide Arcaniolo, Riccardo Giannella, Tommaso Cai, Annarita Cicalese, Cosimo De Nunzio, Giovanni Grimaldi, Virgilio Cicalese, Marco De Sio, Riccardo Autorino, Estêvão Lima, Paolo Fedelini, Mariano Marmo, Marco Capece, Roberto La Rocca, Andrea Tubaro, Ciro Imbimbo, Vincenzo Mirone, Ferdinando Fusco,
BACKGROUND: Evidence about the clinical benefits of Hyperbaric Oxygen Therapy (HBOT) in patients with Fournier's Gangrene (FG) is controversial and inconclusive. We aimed to compare the mortality related to FG between patients undergoing surgical debridement and/or standard antibiotic therapy alone or in combination with HBOT.METHODS: We performed a retrospective multi-institutional observational case-control study. All patients admitted with diagnosis of FG from June 2009 to June 2019 were included ...
Tópico(s): Antimicrobial Resistance in Staphylococcus
2020 - Edizioni Minerva Medica | Minerva Urologica e Nefrologica
Maila Chirivì, Claudia Bearzi, Paolo Rosa, Selenia Miglietta, Francesca Petronella, Elena De Falco, Antonella Calogero, R. Pani, Vincenzo Petrozza, Giovanni Perotto, Roberto Rizzi, Luciano De Sio,
Before entering human clinical studies to evaluate their safety and effectiveness, new drugs and novel medical treatments are subject to extensive animal testing that are expensive and time-consuming. By contrast, advanced technologies enable the development of animal-free models that allow the efficacy of innovative therapies to be studied without sacrificing animals, while providing helpful information and details. We report on the powerful combination of 3D bioprinting (3DB) and photo-thermal ...
Tópico(s): 3D Printing in Biomedical Research
2022 - Multidisciplinary Digital Publishing Institute | International Journal of Molecular Sciences
Feng Wang, Giovanni M. Pauletti, Juntao Wang, Jiaming Zhang, Rodney C. Ewing, Yilong Wang, Donglu Shi,
Folic acid (FA) and doxorubicin (DOX) are coupled separately onto Fe3O4@SiO2 and polystyrene surfaces of a unique polystyrene/Fe3O4@SiO2 Janus structure. This super-paramagnetic, dual-functionalized Janus nanocomposite enables effective tumor cell targeting and internalization via the folate receptor, and induces significant cancer cell death by controlled, stimulus-induced drug release under acidic conditions in endosomal compartments. As a service to our authors and readers, this journal provides ...
Tópico(s): Micro and Nano Robotics
2013 - | Advanced Materials
R. Alfonsetti, Giovanni de Simone, L. Lozzi, M. Passacantando, P. Picozzi, S. Santucci,
Abstract The surface stoichiometry of SiO x thin films ( x = 1,…, 2) has been determined by means of x‐ray photoelectron spectroscopy using: (a) two well established methods involving the determination of the area of the O 1s and Si 2p core level peaks and the analysis of the Si 2p line shape, respectively, and (b) the method of the modified Auger parameter recently suggested. The agreement between the different approaches for determination of the stoichiometry of the films indicates the modified Auger ...
Tópico(s): Ga2O3 and related materials
1994 - Wiley | Surface and Interface Analysis
Gianni Bisogno, Andrea Ferrari, Arcangelo Prete, Chiara Messina, Eleonora Basso, Giovanni Cecchetto, Paolo Indolfi, Giovanni Scarzello, Paolo D’Angelo, Luigi De Sio, Andrea Di Cataldo, Modesto Carli,
Aim The RMS4.99 study was designed to explore the role of multiple sequential high-dose chemotherapy cycles administered early in the treatment of children with metastatic rhabdomyosarcoma. Patients and methods Seventy patients were enrolled and received three cycles of initial standard chemotherapy, followed by a course of cyclophosphamide and etoposide to obtain peripheral blood stem cells (PBSC), then three consecutive high-dose combinations followed by PBSC rescue. This was followed by surgery ...
Tópico(s): Neuroblastoma Research and Treatments
2009 - Elsevier BV | European Journal of Cancer
Giampiero Francica, Maria Franca Meloni, Ilario de Sio, Fulvia Terracciano, Eugenio Caturelli, Laura Riccardi, Paola Roselli, Maddalena Iadevaia, Mariano Scaglione, Giovanni Lenna, Jason Chiang, Maurizio Pompili,
Abstract Purpose To retrospectively characterize the prevalence and impact of contrast-enhanced ultrasound (CEUS) as a guidance technique for the biopsy of liver target lesions (LTLs) at six interventional ultrasound centers. Materials and Methods The six participating centers retrospectively selected all patients in whom biopsy needles were positioned in LTLs during CEUS. The prevalence of CEUS-guided biopsies at each center between 2005 and 2016, contrast agent consumption, procedure indications, ...
Tópico(s): Hepatitis B Virus Studies
2017 - Georg Thieme Verlag | Ultraschall in der Medizin - European Journal of Ultrasound