Jérôme R. Lechien, Carlos M. Chiesa‐Estomba, Luigi Angelo Vaira, Giacomo De Riu, Giovanni Cammaroto, Younès Chekkoury‐Idrissi, Marta P. Circiu, Léa Distinguin, Fabrice Journé, Christophe de Terwangne, Shahram Machayekhi, Maria Rosaria Barillari, Christian Calvo‐Henríquez, Stéphane Hans, Sven Saussez,
To investigate prevalence and epidemiological and clinical factors associated with olfactory dysfunction (OD) and gustatory dysfunction (GD) in COVID-19 patients according to the disease severity.Cross-sectional study.A total of 2579 patients with a positive diagnosis of COVID-19 were identified between March 22 and June 3, 2020 from 18 European hospitals. Epidemiological and clinical data were extracted. Otolaryngological symptoms, including OD and GD, were collected through patient-reported outcome ...
Tópico(s): Biochemical Analysis and Sensing Techniques
2021 - Springer Science+Business Media | European Archives of Oto-Rhino-Laryngology
Jérôme R. Lechien, Carlos M. Chiesa‐Estomba, Luigi Angelo Vaira, Giacomo De Riu, Giovanni Cammaroto, Younès Chekkoury‐Idrissi, Marta P. Circiu, Léa Distinguin, Fabrice Journé, Christophe de Terwangne, Shahram Machayekhi, Maria Rosaria Barillari, Christian Calvo‐Henríquez, Stéphane Hans, Sven Saussez,
In the original publication of the article, one of the co-author's name was published incorrectly as "Liugi A. Varia". The correct name should read as "Luigi A. Vaira".
Tópico(s): Biochemical Analysis and Sensing Techniques
2021 - Springer Science+Business Media | European Archives of Oto-Rhino-Laryngology
Luigi Angelo Vaira, Jérôme R. Lechien, Vincenzo Abbate, Fabiana Allevi, Giovanni Audino, Giada Anna Beltramini, Michela Bergonzani, Paolo Boscolo‐Rizzo, Gianluigi Califano, Giovanni Cammaroto, Carlos M. Chiesa‐Estomba, Umberto Committeri, Salvatore Crimi, Nicholas R. Curran, Francesco Di Bello, Arianna Di Stadio, Andrea Frosolini, Guido Gabriele, Isabelle Gengler, F. Lonardi, Fabio Maglitto, Miguel Mayo‐Yáñez, Marzia Petrocelli, Resi Pucci, Alberto Maria Saibene, Gianmarco Saponaro, Alessandro Tel, Franco Trabalzini, Eleonora M. C. Trecca, Valentino Vellone, Giovanni Salzano, Giacomo De Riu,
The widespread diffusion of Artificial Intelligence (AI) platforms is revolutionizing how health-related information is disseminated, thereby highlighting the need for tools to evaluate the quality of such information. This study aimed to propose and validate the Quality Assessment of Medical Artificial Intelligence (QAMAI), a tool specifically designed to assess the quality of health information provided by AI platforms.
Tópico(s): Patient-Provider Communication in Healthcare
2024 - Springer Science+Business Media | European Archives of Oto-Rhino-Laryngology
Luigi Angelo Vaira, Jérôme R. Lechien, Vincenzo Abbate, Fabiana Allevi, Giovanni Audino, Giada Anna Beltramini, Michela Bergonzani, Alessandro Bolzoni, Umberto Committeri, Salvatore Crimi, Guido Gabriele, F. Lonardi, Fabio Maglitto, Marzia Petrocelli, Resi Pucci, Gianmarco Saponaro, Alessandro Tel, Valentino Vellone, Carlos M. Chiesa‐Estomba, Paolo Boscolo‐Rizzo, Giovanni Salzano, Giacomo De Riu,
Abstract Objective To investigate the accuracy of Chat‐Based Generative Pre‐trained Transformer (ChatGPT) in answering questions and solving clinical scenarios of head and neck surgery. Study Design Observational and valuative study. Setting Eighteen surgeons from 14 Italian head and neck surgery units. Methods A total of 144 clinical questions encompassing different subspecialities of head and neck surgery and 15 comprehensive clinical scenarios were developed. Questions and scenarios were inputted ...
Tópico(s): Clinical Reasoning and Diagnostic Skills
2023 - Wiley | Otolaryngology
Luigi Angelo Vaira, Giovanni Salzano, Giacomo De Riu,
Early detection and isolation of pauci-symptomatic patients with coronavirus disease 19 (COVID-19) is proving to be a key factor in the fight against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The first European case series are reporting a high frequency of olfactory and gustatory dysfunctions in COVID-19 patients.1Vaira L.A. Salzano G. Deiana G. et al.Ageusia and anosmia: common findings in COVID-19 patients.Laryngoscope. 2020; https://doi.org/10.1002/lary.28692Crossref PubMed ...
Tópico(s): Essential Oils and Antimicrobial Activity
2020 - Elsevier BV | British Journal of Oral and Maxillofacial Surgery
Luigi Angelo Vaira, Giovanna Deiana, Alessandro G. Fois, Pietro Pirina, Giordano Madeddu, Andrea De Vito, Sergio Babudieri, Marzia Petrocelli, Antonello Serra, Francesco Bussu, Enrica Ligas, Giovanni Salzano, Giacomo De Riu,
Abstract Background The first European case series are detecting a very high frequency of chemosensitive disorders in COVID‐19 patients, ranging between 19.4% and 88%. Methods Olfactory and gustatory function was objectively tested in 72 COVID‐19 patients treated at University Hospital of Sassari. Results Overall, 73.6% of the patients reported having or having had chemosensitive disorders. Olfactory assessment showed variable degree hyposmia in 60 cases and anosmia in two patients. Gustatory assessment ...
Tópico(s): Essential Oils and Antimicrobial Activity
2020 - Wiley | Head & Neck
GianPietro Sechi, Pierluigi De Riu, O. Mameli, Giovanni Deiana, Giovanni Antonio Cocco, Giulio Rosati,
The objective of this study was to document the convulsant properties of thiocolchicoside in rats, and to characterise the electroclinical pattern of epileptic seizures. Experiments were carried out in three groups of male Wistar rats: in group A, thiocolchicoside was applied topically to the pia, or given by microinjection to the cerebral cortex (2 microg/microl); in group B, the drug was administered parenterally (6 mg/kg) to rats with minimal lesions of the dura and arachnoid membranes; in group ...
Tópico(s): Epilepsy research and treatment
2003 - Elsevier BV | Seizure
Giacomo De Riu, Nicola De Riu, Giovanni Spanó, Angelo Pizzigallo, Giovanna Petrone, Antonio Tullio,
Objective The mechanisms for integrating titanium implants in recipient bone are still not well defined, and it is not known whether the process of bone formation around implants inserted into grafts is the same as that described for titanium implants in nongrafted cortical bone. This study compared the histology, stability, and osseointegration of titanium implants inserted in cortical bone with and without a simultaneous autologous cortical bone graft in an experimental animal model. Methods Thirty ...
Tópico(s): Orthopaedic implants and arthroplasty
2007 - Elsevier BV | Oral Surgery Oral Medicine Oral Pathology Oral Radiology and Endodontology
Luigi Angelo Vaira, Giovanni Salzano, Giovanna Deiana, Giacomo De Riu,
... for more papers by this authorGiovanni Salzano MD, Giovanni Salzano MD Maxillofacial Surgery Unit, University Hospital of Naples "Federico II", Naples, ItalySearch for more papers by this authorGiovanna Deiana MD, Giovanna Deiana MD Hygiene and Hospital Infection Control Operative Unit, University Hospital of Sassari, Sassari, ItalySearch for more papers by this authorGiacomo De Riu MD, FEBOMFS, Giacomo De Riu MD, FEBOMFS Maxillofacial ... for more papers by this authorGiovanni Salzano MD, Giovanni Salzano MD Maxillofacial Surgery Unit, University Hospital of Naples "Federico II", Naples, ItalySearch for more papers by this authorGiovanna Deiana MD, Giovanna Deiana MD Hygiene and Hospital Infection Control Operative Unit, University Hospital of Sassari, Sassari, ItalySearch for more papers by this authorGiacomo De Riu MD, FEBOMFS, Giacomo De Riu MD, FEBOMFS Maxillofacial ...
Tópico(s): Lymphatic System and Diseases
2020 - Wiley | The Laryngoscope
Olindo Massarelli, Luigi Angelo Vaira, Andrea Biglio, Roberta Gobbi, Giovanni Dell’Aversana Orabona, Giacomo De Riu,
Abstract Background Sensory restoration of the oral cavity is a primary aim of reconstructive surgery in posttraumatic or postablative defects. Sensitivity plays a key role in oral function, whose impairment strongly affects the patient's quality of life. Cheek myomucosal flaps provide a reliable and tissue‐like reconstruction of these regions but their sensitive recovery, which we still know little about, deserves thorough assessment. Methods In this retrospective study, the myomucosal cheek flaps ...
Tópico(s): Reconstructive Facial Surgery Techniques
2017 - Wiley | Head & Neck
Olindo Massarelli, Luigi Angelo Vaira, Roberta Gobbi, Andrea Biglio, Giovanni Dell’Aversana Orabona, Giacomo De Riu,
Oropharyngeal reconstruction after ablative surgery is a challenge. The results of a retrospective study of 17 patients who underwent total or sub-total soft palate reconstruction with a buccinator myomucosal island flap, between 2008 and 2016, are reported herein. An analysis of flap type and size, harvesting time, and postoperative complications was performed. Patients underwent standardized tests to assess the recovery of sensitivity, deglutition, quality of life (QoL), and donor site morbidity, ...
Tópico(s): Tracheal and airway disorders
2017 - Elsevier BV | International Journal of Oral and Maxillofacial Surgery
Luigi Angelo Vaira, Giovanni Salzano, Giovanna Deiana, Giacomo De Riu,
In a not negligible number of patients affected by COVID-19 (coronavirus disease 2019), especially if paucisymptomatic, anosmia and ageusia can represent the first or only symptomatology present. Laryngoscope, 130:1787-1787, 2020.
Tópico(s): Neurological Disorders and Treatments
2020 - Wiley | The Laryngoscope
Giovanni Piccolo, Fulvia Bovera, Nicola De Riu, S. Marono, Fulvio Salati, Roberto Cappuccinelli, Giuseppe Moniello,
The aim of this study was to evaluate the effect of two diets with different protein/fat ratios (P/F) (diet A: P/F 2.26; diet B: P/F 3.36) on the chemical composition, fatty acid profile and some somatic indexes of meagre (Argyrosomus regius). The trial was carried out on two groups of meagre raised in two different sea cages during 15 months. At the end of the production cycle biometric measures as well as chemical-nutritional analysis of the fillets were conducted on 25 fishes per group. Diet A, ...
Tópico(s): Reproductive biology and impacts on aquatic species
2008 - Taylor & Francis | Italian Journal of Animal Science
Luigi Angelo Vaira, Giacomo De Riu, Giovanni Salzano, Fabio Maglitto, Paolo Boscolo‐Rizzo, Jérôme R. Lechien,
Smell Taste Taste dysfunction Maxillo-
Tópico(s): Allergic Rhinitis and Sensitization
2022 - Elsevier BV | American Journal of Otolaryngology
Giuseppe Moniello, Fulvia Bovera, Nicola De Riu, Giovanni Piccolo, Walter Pinna, Carmelo Di Meo,
In order to better define the effect of the sex on the metabolic profile of young ostriches (Struthio camelus domesticus), forty birds were divided into two groups by sex (20 males vs 20 females). The animals were fed ad libitum natural pasture and corn silage. The daily ration was completed by administering 1200 g/head of a commercial concentrate with the following chemical composition expressed as a percentage of dry matter: crude protein 18.8, crude fibre 8.4, ether extract 3.6, ash 7.5. After ...
Tópico(s): Pharmacological Effects and Assays
2006 - Taylor & Francis | Italian Journal of Animal Science
Luigi Angelo Vaira, Maria Teresa Raho, Damiano Soma, Giovanni Salzano, Giovanni Dell’Aversana Orabona, Pasquale Piombino, Giacomo De Riu,
Objective: To evaluate intraoperative complications and postsurgical sequelae associated with arthrocentesis of the TMJ, including injection of Sodium Hyaluronate. Methods: This retrospective study evaluated 433 arthrocentesis procedures performed in 315 patients between January 2009 and August 2016. The authors reviewed the complications identified during the procedure and the follow-up period. Results: Temporary swelling of the periarticular tissues (95.1%) or the external auditory canal (23.5%), ...
Tópico(s): Oropharyngeal Anatomy and Pathologies
2017 - Taylor & Francis | CRANIO®
Luigi Angelo Vaira, Damiano Soma, Silvio Mario Meloni, Giovanni Dell’Aversana Orabona, Pasquale Piombino, Giacomo De Riu,
Tópico(s): Vestibular and auditory disorders
2016 - Springer Science+Business Media | Oral and Maxillofacial Surgery
Luigi Angelo Vaira, Giovanni Salzano, Giovanna Deiana, Francesco Antonio Salzano, Giacomo De Riu,
... by this authorGiacomo De Riu MD, FEBOMFS, Giacomo De Riu MD, FEBOMFS Maxillofacial Surgery Unit, University Hospital of Sassari, Sassari, ItalySearch for more papers by this author Luigi A. Vaira MD, Corresponding Author Luigi A. Vaira MD [email protected] orcid.org/0000-0002-7789-145X Maxillofacial Surgery Unit, University Hospital of Sassari, Sassari, ItalySearch for more papers by this authorGiovanni Salzano MD, Giovanni Salzano MD Maxillofacial Surgery Unit, University Hospital of ...
Tópico(s): Olfactory and Sensory Function Studies
2020 - Wiley | The Laryngoscope
Sven Saussez, Luigi Angelo Vaira, Carlos M. Chiesa‐Estomba, Serge Le Bon, Mihaéla Horoi, Giovanna Deiana, Marzia Petrocelli, Philippe Boelpaep, Giovanni Salzano, Mohamad Khalifé, Stéphane Hans, Giacomo De Riu, Claire Hopkins, Jérôme R. Lechien,
Background: The objective of this study was to investigate the efficacy and safety of early administration of oral corticosteroids (OC) or nasal corticosteroids (NC) as an add-on to olfactory training (OT) versus OT alone in patients with olfactory dysfunction (OD) related to coronavirus disease 2019 (COVID-19). Methods: Patients with a positive diagnosis of COVID-19 and OD were prospectively recruited from March 22 to December 15, 2020 from 4 European hospitals. Patients had confirmed OD on psychophysical ...
Tópico(s): Sinusitis and nasal conditions
2021 - Multidisciplinary Digital Publishing Institute | Pathogens
Luigi Angelo Vaira, Claire Hopkins, Ann Sandison, Alessia Manca, Nikolaos Machouchas, D Turilli, Jérôme R. Lechien, Maria Rosaria Barillari, Giovanni Salzano, Andrea Cossu, Sven Saussez, Giacomo De Riu,
Olfactory dysfunction represents one of the most frequent symptoms of coronavirus disease 2019, affecting about 70 per cent of patients. However, the pathogenesis of the olfactory dysfunction in coronavirus disease 2019 has not yet been elucidated.This report presents the radiological and histopathological findings of a patient who presented with anosmia persisting for more than three months after infection with severe acute respiratory syndrome coronavirus-2.The biopsy demonstrated significant ...
Tópico(s): Essential Oils and Antimicrobial Activity
2020 - Cambridge University Press | The Journal of Laryngology & Otology
Luigi Angelo Vaira, Claire Hopkins, Marzia Petrocelli, Jérôme R. Lechien, Damiano Soma, Federica Giovanditto, Davide Rizzo, Giovanni Salzano, Pasquale Piombino, Sven Saussez, Giacomo De Riu,
The lack of objective data makes it difficult to establish the prognostic value of chemosensitive disorders in coronavirus disease 2019 (COVID-19) patients. We aimed to prospectively monitor patients diagnosed with COVID-19 to see if the severity of olfactory and gustatory dysfunction associates with subsequent disease severity.Multicentre prospective study that recruited 106 COVID-19 subjects at diagnosis. Chemosensitive functions were assessed with psychophysical tests within 4 days of clinical ...
Tópico(s): Essential Oils and Antimicrobial Activity
2020 - BioMed Central | Journal of Otolaryngology - Head and Neck Surgery
Umberto Committeri, Antonio Arena, Emanuele Carraturo, Martina Austoni, Cristiana Germano, Giovanni Salzano, Giacomo De Riu, Francesco Giovacchini, Fabio Maglitto, Vincenzo Abbate, Paola Bonavolontà, Luigi Califano, Pasquale Piombino,
Zygomaticomaxillary complex and isolated orbital walls fractures are one of the most common fractures of the midface, often presenting orbital symptoms and complications. Our study was born with the aim of understanding the trend in the incidence of orbital presurgical symptoms, specifically diplopia, enophthalmos and exophthalmos, in the Campania Region in southern Italy. We conducted a retrospective, monocentric observational study at the Maxillofacial Surgery Unit of the Federico II University ...
Tópico(s): Dental Radiography and Imaging
2023 - Multidisciplinary Digital Publishing Institute | Journal of Clinical Medicine
Luigi Angelo Vaira, Giovanni Salzano, Alessandro G. Fois, Pasquale Piombino, Giacomo De Riu,
To the Editor, The rapid spread of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in Europe and America is enabling researchers to acquire a large amount of clinical data. Interestingly, some of these findings differ significantly from those reported in Chinese case studies. In particular, the presence of taste and smell alterations seems to be a frequent clinical feature of the coronavirus disease 19 (COVID-19), with a frequency ranging from 19.4% to 88% of patients.1-4 The exact ...
Tópico(s): Advanced Chemical Sensor Technologies
2020 - Wiley | International Forum of Allergy & Rhinology
Luigi Angelo Vaira, Andrea Biglio, A Favro, Giovanni Salzano, Vincenzo Abbate, Jérôme R. Lechien, Giacomo De Riu,
The aim of this study was to retrospectively analyse a series of patients with posterior mandibular atrophy rehabilitated with custom-made subperiosteal implants. The study included patients with severe posterior mandibular atrophy who had undergone rehabilitation with subperiosteal implants between September 2018 and August 2022 in the Maxillofacial Surgery Operative Unit of the University Hospital of Sassari. Complications and the success rate were reviewed. Data from 30 implants placed in 17 ...
Tópico(s): Temporomandibular Joint Disorders
2024 - Elsevier BV | International Journal of Oral and Maxillofacial Surgery
Luigi Angelo Vaira, Claire Hopkins, Marzia Petrocelli, Jérôme R. Lechien, Sebastiano Cutrupi, Giovanni Salzano, Carlos M. Chiesa‐Estomba, Sven Saussez, Giacomo De Riu,
BACKGROUND: The growing number of COVID-19 patients with long-lasting olfactory disorders makes it necessary to identify effective treatments that enhance the spontaneous recovery of olfactory function. METHODS: Multicentre randomised case-control study that involved 18 patients with COVID-19 related anosmia or severe hyposmia for more than 30 days. Nine patients were prescribed systemic prednisone and nasal irrigation with betamethasone, ambroxol and rinazine for 15 days. The other 9, untreated, ...
Tópico(s): Allergic Rhinitis and Sensitization
2020 - European Rhinologic Society | Rhinology Journal
Luigi Angelo Vaira, Olindo Massarelli, Roberta Gobbi, Damiano Soma, Giovanni Dell’Aversana Orabona, Pasquale Piombino, Giacomo De Riu,
Tópico(s): Cleft Lip and Palate Research
2017 - Springer Science+Business Media | European Journal of Plastic Surgery
Federica Giovanditto, Damiano Soma, Luigi Angelo Vaira, Alberto Pispero, Niccolò Lombardi, Federico Ristoldo, Umberto Mariani, Silvia Pizzi, Antonio Isola, Pierantonio Smania, Massimo Albanese, Antonio D’Agostino, Paolo Appendino, Ernesto Scatà, Maria Teresa Raho, Roberta Gobbi, Elena Carta, Olindo Massarelli, Aurea Immacolata Lumbau, Giovanni Spanó, Giacomo De Riu,
Among healthcare workers, oral and maxillofacial surgeons are some of the most exposed to coronavirus disease (COVID-19). The aim of this retrospective study was to develop suggestions for continuing the work of oral and maxillofacial surgeons using a safe protocol for elective and urgent aerosol-generating procedures that could prevent the onset of new clusters. Based on the results obtained and a guidelines review of those Asian countries that had promptly managed the current pandemic, the following ...
Tópico(s): Infection Control and Ventilation
2022 - Elsevier BV | Journal of Cranio-Maxillofacial Surgery
Giovanni Salzano, Fabio Maglitto, A. Bisogno, Luigi Angelo Vaira, Giacomo De Riu, Matteo Cavaliere, Arianna Di Stadio, Massimo Mesolella, Gaetano Motta, Franco Ionna, Luigi Califano, Francesco Antonio Salzano,
La sindrome da apnee notturne: correlazione con l’obesità e gestione del paziente obeso.
Tópico(s): Regulation of Appetite and Obesity
2021 - Pacini Editore Medicina | Acta Otorhinolaryngologica Italica
Luigi Angelo Vaira, Giovanni Salzano, Marzia Petrocelli, Giovanna Deiana, Francesco Antonio Salzano, Giacomo De Riu,
Chemosensitive disorders are very frequent in the early stages of COVID-19 and in paucisymptomatic cases. These patients are typically placed in home quarantine. This study has the aim of validating a new olfactory and gustatory objective evaluation test in these patients.Thirty-three home-quarantined COVID-19 patients have undergone a self-administered chemosensitive test the day before the control swab. On this occasion, the patients underwent operator-administered already validated tests. The ...
Tópico(s): Neurobiology and Insect Physiology Research
2020 - Wiley | Head & Neck
Luigi Angelo Vaira, Jérôme R. Lechien, Giovanni Salzano, Francesco Antonio Salzano, Fabio Maglitto, Sven Saussez, Giacomo De Riu,
Chemosensitive dysfunctions are now considered as frequent and early symptoms of coronavirus disease 2019 (COVID-19). In the last few weeks, researchers' greatest efforts have been focusing mainly on the analysis of olfactory disorders, neglecting taste dysfunctions. According to our psychophysical evaluations, it can be inferred that the pathogenesis of taste disorders in COVID-19 patients is largely smell-independent. Moreover, isolated gustatory disorders are highly specific of SARS-CoV-2 infection. ...
Tópico(s): Biochemical Analysis and Sensing Techniques
2020 - Springer Nature | Indian Journal of Otolaryngology and Head & Neck Surgery