Natsumi Takamaru, Hiroyuki Nagai, Go Ohe, Tetsuya Tamatani, Kaori Sumida, S Kitamura, Yoshihiro Miyamoto,
The zygomaticus implant was developed for patients with severe bone resorption of the posterior maxilla. These may eliminate or minimize the need for bone grafting. Although the zygomaticus implant has shown a remarkable success rate in this difficult-to-treat patient population, the method requires an advanced surgical technique and carries an increased risk of complications. There have been few anatomical studies on the zygomatic bone in relation to the insertion of zygomaticus implants. The height ...
Tópico(s): Bone Tissue Engineering Materials
2015 - Elsevier BV | International Journal of Oral and Maxillofacial Surgery
Leila Basti, Satoshi Nagai, Jiyoji Go, Sho Okano, Kiyohito Nagai, Ryuichi Watanabe, Toshiyuki Suzuki, Yuji Tanaka,
The effects of four harmful and potentially harmful dinoflagellates, Alexandrium affine, Alexandrium catenella, Karenia mikimotoi and Karenia papilionacea, on the early-life development of Japanese pearl oyster, Pinctada fucata martensii, were assessed. Density- and time-dependent, mild to severe effects on cleavage, hatching, D-larvae, and pre-settling larvae of pearl oysters were found. The non-PST-producer A. affine was highly toxic to both cleavage and hatching with potent lytic activity at ...
Tópico(s): Protist diversity and phylogeny
2015 - Elsevier BV | Harmful Algae
Leila Basti, Kiyohito Nagai, Jiyoji Go, Sho Okano, Tatsuya Oda, Yuji Tanaka, Satoshi Nagai,
The inimical effects of the ichthyotoxic harmful algal bloom (HAB)-forming raphidophytes Heterosigma akashiwo, Chattonella marina, and Chattonella antiqua on the early-life stages of the Japanese pearl oyster Pinctada fucata martensii were studied. Fertilized eggs and developing embryos were not affected following exposure to the harmful raphidophytes; however, all three algal species severely affected trochophores and D-larvae, early-stage D-larvae, and late-stage pre-settling larvae. Exposure to ...
Tópico(s): Marine Bivalve and Aquaculture Studies
2016 - Elsevier BV | Harmful Algae
Hiroshi Mochimaru, Norihiro Nagai, Go Hasegawa, Chie Kudo‐Saito, Tomonori Yaguchi, Yoshihiko Usui, Toshihide Kurihara, Takashi Koto, Shingo Satofuka, Hajime Shinoda, Yoko Ozawa, Kazuo Tsubota, Yutaka Kawakami, Susumu Ishida,
To investigate whether the induction of cellular immunity against vascular endothelial growth factor receptor (VEGFR) 2 inhibits the development of choroidal neovascularization (CNV).H-2Db-restricted peptide corresponding to amino acids 400 to 408 of VEGFR2 was used as an epitope peptide. Dendritic cells (DCs) were harvested from bone marrow progenitors of C57BL/6 mice. Six-week-old C57BL/6 mice received subcutaneous injections of the epitope peptide-pulsed mature DCs three times at 6-day intervals. ...
Tópico(s): Angiogenesis and VEGF in Cancer
2007 - Cadmus Press | Investigative Ophthalmology & Visual Science
Tsutomu Konno, Jungha Chae, Masashi Kanda, Go Nagai, Kazushige Tamura, Takashi Ishihara, Hiroki Yamanaka,
Tópico(s): Inorganic Fluorides and Related Compounds
2003 - Elsevier BV | Tetrahedron
Kotohiro Nomura, Mari Oshima, Takato Mitsudome, Hitoshi Harakawa, Hao Peng, Ken Tsutsumi, Go Nagai, Toshiaki Ina, Hikaru Takaya, Wen‐Hua Sun, Seiji Yamazoe,
(Imido)vanadium(V) dichloride complexes containing 2-(2′-benzimidazolyl)-6-methylpyridine ligand (L) of type V(NR)Cl2(L) [R = 1-adamantyl (Ad, 1), C6H5 (2), and 2,6-Me2C6H3 (3)] have been prepared, and their structures were determined by X-ray crystallography as distorted trigonal bipyramidal structures around vanadium. Reactions with ethylene using 1–3 in the presence of methylaluminoxane (MAO) afforded a mixture of oligomer and polymers, and the compositions were affected by the imido ligand employed. ...
Tópico(s): Carbon dioxide utilization in catalysis
2017 - American Chemical Society | ACS Omega
Go Nagai, Takato Mitsudome, Ken Tsutsumi, Shunsuke Sueki, Toshiaki Ina, Matthias Tamm, Kotohiro Nomura,
Effect of Al cocatalyst in ethylene polymerization using (imido)vanadium(V) complexes containing anionic N-heterocyclic carbenes with a weakly coordinating borate moiety in 4-position (WCA-NHC), [V(N-2,6-Me2C6H3)Cl2(WCA-NHC)] [1; NHC=1,3-bis(2,6-dimethylphenyl)-imidazolin-2-ylidene], have been explored. The activities by 1 upon presence of AliBu3 in ethylene polymerization and in the copolymerization with norbornene (NBE) were higher than those in the presence of MAO, and the resultant poly(ethylene- ...
Tópico(s): Carbon dioxide utilization in catalysis
2017 - Japan Petroleum Institute | Journal of the Japan Petroleum Institute
Kotohiro Nomura, Takato Mitsudome, Atsushi Igarashi, Go Nagai, Ken Tsutsumi, Toshiaki Ina, Takuya Omiya, Hikaru Takaya, Seiji Yamazoe,
V(NAd)Me2(L) [2a, L = 2-ArNCH2(C5H4N), Ar = 2,6-Me2C6H3], prepared from V(NAd)Cl2(L) (1) by reaction with LiMe (2.0 equiv), exhibited remarkable catalytic activities for ethylene dimerization in the presence of MAO affording 1-butene with high selectivity [TOF = 1 120 000–1 530 000 h–1 (311–425 s–1), C4′ = 97.1–98.4%], and the catalyst performances (activity, selectivity) were similar to those by the dichloride analogue (1) under the same conditions. The dimethyl complex (2a) reacted with 1.0 equiv of R′OH to yield ...
Tópico(s): Polyoxometalates: Synthesis and Applications
2017 - American Chemical Society | Organometallics
Noriyuki Ogawa, Takehide Kimura, Fumi Umehara, Yuki Katayama, Go Nagai, Keiko Suzuki, Kazuo Aisaka, Yukie Maruyama, Takafumi Itoh, Wataru Hashimoto, Kousaku Murata, Michio Ichimura,
The currently available haemoglobin A1c (HbA1c) enzymatic assay consists of two specific steps: proteolysis of HbA1c and oxidation of the liberated fructosyl peptide by fructosyl peptide oxidase (FPOX). To develop a more convenient and high throughput assay, we devised novel protease-free assay system employing modified FPOX with HbA1c oxidation activity, namely HbA1c direct oxidase (HbA1cOX). AnFPOX-15, a modified FPOX from Aspergillus nidulans, was selected for conversion to HbA1cOX. As deduced from ...
Tópico(s): Enzyme Catalysis and Immobilization
2019 - Nature Portfolio | Scientific Reports
Kotohiro Nomura, Go Nagai, Itsuki Izawa, Takato Mitsudome, Matthias Tamm, Seiji Yamazoe,
(Arylimido)vanadium(V) dichloride complexes containing anionic N-heterocyclic carbene (NHC) ligands that contain weakly coordinating B(C6F5)3 moieties (WCA-NHC) of the type [V(NAr)Cl2(WCA-NHC-Ar′)] (5, Ar = 2,6-Me2C6H3, Ar′ = 2,6-iPr2C6H3) showed significant catalytic activity for ethylene polymerization in the presence of Al cocatalysts (MAO and AliBu3); the activity by the 5–MAO catalyst (19 500 kg-PE/mol-V·h; TOF 11 600 min–1) is the highest among those reported using the other (imido)vanadium(V) complexes ...
Tópico(s): Carbon dioxide utilization in catalysis
2019 - American Chemical Society | ACS Omega
Kotohiro Nomura, Go Nagai, Alexandre Nasr, Ken Tsutsumi, Yuta Kawamoto, Koji Koide, Matthias Tamm,
Synthesis and structural analysis of half-titanocenes containing anionic N-heterocyclic carbenes with a weakly coordinating borate [B(C6F5)3] moiety (WCA-NHC) of the type, [Cp′TiX2(WCA-NHC)] [Cp′ = C5H5, tBuC5H4; X = Cl, Me; NHC = 1,3-bis(2,6-dimethylphenyl)imidazolin-2-ylidene], have been explored. The Ti–C bond distances between titanium and the N-heterocyclic carbene carbon atoms [Ti–CNHC = 2.214(3)–2.246(3) Å] are longer than the Ti–methyl bond distances in the dimethyl complexes [2.063(5)–2.122(9) Å]; the ...
Tópico(s): Synthetic Organic Chemistry Methods
2019 - American Chemical Society | Organometallics
Kiyohito Nagai, Jyoji Go, Susumu Segawa, Tsuneo Honjo,
In this study, we prove that the mass die-offs occurring in conjunction with red adductor disease in pearl oysters are caused by an infection. Our research also reveals the influence of water temperature on the onset of the disease and its progress, and we propose measures that are effective in mitigating harm from the disease. To analyze the effect of water temperature on the onset and progress of the disease, laboratory infection experiments were performed over a range of water temperatures (13 ° ...
Tópico(s): Parasite Biology and Host Interactions
2006 - Elsevier BV | Aquaculture
Kotohiro Nomura, Ken Tsutsumi, Go Nagai, Takuya Omiya, Toshiaki Ina, Seiji Yamazoe, Takato Mitsudome,
Effects of ligand and ligand substituents in a series of (imido)vanadium(V) complexes containing monodentate anionic ancillary donor ligands of the type, V(NAr)Cl2(L) [Ar = 2,6-Me2C6H3; L = OAr, O-2,6-Ph2C6H3, N = CtBu2, 1,3-tBu2(CHN)2C = N, WCA-NHC (anionic N-heterocyclic carbenes with a weakly coordinating borate moiety)] and V(NAd)Cl2(OAr) (Ad = 1-adamantyl), were explored by the solution V K-edge XANES (pre-edge and edge region) spectra. No significant differences in the pre-edge (and the edge) peaks were observed ...
Tópico(s): Catalytic Alkyne Reactions
2018 - Japan Petroleum Institute | Journal of the Japan Petroleum Institute
Hirokazu Nagai, Kunihiko Terada, Go Watanabe, Yasuharu Ueno, Namiko Aiba, Tomomi Shibuya, Masami Kawagoe, Takashi Kameda, Mitsuru Sato, Haruki Senoo, Toshihiro Sugiyama,
The liver is believed to contain stem cells that can differentiate into either hepatocytes or biliary epithelial cells. In the present study, we established a nonhepatocytic epithelial cell line from the normal livers of adult rats. The established cells, designated HSL cells, were immunoreactive against α-fetoprotein, but neither albumin nor cytokeratin 19. To demonstrate the differentiation potential of HSL cells in vitro, the cells were cocultured with hepatic stellate cells as a mixture or separately ...
Tópico(s): Pancreatic function and diabetes
2002 - Elsevier BV | Biochemical and Biophysical Research Communications
... Japanese Spiderman TV series of the 1970s, and Go Nagai's spoof Kekkō Kamen, the busty, underwear-clad ...
Tópico(s): Chinese history and philosophy
2014 - Routledge | Japan Forum
Kiyohito Nagai, Tsuneo Honjo, Jyoji Go, Hiroyasu Yamashita, Seok Jin Oh,
We developed a system for the early detection of noxious dinoflagellate Heterocapsa circularisquama blooms by utilizing the response of Akoya pearl oysters (Pinctada fucata) to H. circularisquama cells. The system is based on valve movement activity in bivalves. The movements were measured by means of a magnet on one valve to a Hall element sensor on the other valve connected by thin cables to a recording device. In filtered sea water, valve movement activity of pearl oysters as displayed on the ...
Tópico(s): Marine Biology and Ecology Research
2006 - Elsevier BV | Aquaculture
Suguru Inoue, Yuji Oshima, Kiyohito Nagai, Takashi Yamamoto, Jyoji Go, Norihisa Kai, Tsuneo Honjo,
Abstract We examined the effect of tributyltin (TBT) on reproduction of the pearl oyster ( Pinctada fucata martensii ). In a maternal exposure test, five female pearl oysters were exposed to TBT at measured concentrations of 0 (control), 0.092, or 0.191 μg/L at 25°C for one week, and the embryo developmental success (the ratio of normal D‐larvae to all larvae) was measured. The embryo developmental success was significantly decreased in the 0.191‐μg/L treatment group (65.5%) compared to that in the control ...
Tópico(s): Marine Bivalve and Aquaculture Studies
2004 - Wiley | Environmental Toxicology and Chemistry
Tsutomu Konno, Go Nagai, Takashi Ishihara,
Tópico(s): Catalytic Alkyne Reactions
2006 - Elsevier BV | Journal of Fluorine Chemistry
S. Nagai, Go Hirano, Takeru Bessho, Khalid Satori,
The state of dye adsorption on TiO2 electrodes in dye-sensitized solar-cell (DSSC) systems is important for its power-conversion efficiency (PCE). We propose a non-destructive and quantitative method to evaluate the amount of adsorbed dye on TiO2 electrodes by using micro-Raman spectroscopy. The Raman peak intensity ratio of adsorbed dye to TiO2, Id/It, is defined as a dye adsorption parameter. Based on a comparison between Id/It and the amount of dye evaluated from UV–vis absorption, the quantitativity ...
Tópico(s): Quantum Dots Synthesis And Properties
2014 - Elsevier BV | Vibrational Spectroscopy
Tomohiro Takaya, Kiyoshi Niwa, Motoki Muraoka, Ikuo Ogita, Nagai Noriko, Ryo-ichi Yano, Go Kimura, Yukako Yoshikawa, Hiroshi Yoshikawa, Kanji Takada,
The relationship between in vitro drug release characteristics from colon delivery systems and in vivo drug absorption was investigated using three kinds of delayed-release systems. 5-aminosalicylic acid (5-ASA), tegafur (FT) and carbamazepine (CBZ) were selected as model drugs. Pressure-controlled colon delivery capsules (PCC) for liquid preparations, time-controlled colon delivery capsules (TCC) for liquid and solid preparations and Eudragit S coated tablets for solid preparations were used in this ...
Tópico(s): Advanced Drug Delivery Systems
1998 - Elsevier BV | Journal of Controlled Release
Yasuhiko Watarai, Haruaki Satoh, Miyuki Matubara, Kazue Asakawa, Harumi Kamaguchi, Sachiko Nagai, Yukihiro Murase, Munehiro Yokoyama, Go Kimura, Koichi Tamura, Yuichi Sugisaki,
To compare the cytomorphologic features of urine obtained from two different kinds of urinary diversions constructed after total bladder resection.The smears of urine from 11 ileal conduits and 6 Indiana pouches were evaluated. All patients underwent total bladder resection due to transitional cell carcinoma (TCC) or other kinds of cancer before urine diversion.The cytologic features of Indiana pouch urine include degenerated, small, round cells without columnar cells derived from intestinal epithelium. ...
Tópico(s): Colorectal Cancer Screening and Detection
2000 - Karger Publishers | Acta Cytologica
Carol S. Weissert, Jack H. Knott,
... of Foundations, 29 . Crossref, Medline, Google Scholar 6. Nagai , et al. ., Giving for Social Change; and Go to the article, Google Scholar Iglehart J.K. , “ ...
Tópico(s): Nonprofit Sector and Volunteering
1995 - Project HOPE | Health Affairs
Masako Fujioka‐Kobayashi, Kanji Tsuru, Hirokazu Nagai, Kenji Fujisawa, Takaharu Kudoh, Go Ohe, Kunio Ishikawa, Youji Miyamoto,
Carbonate apatite-coated calcium carbonate (CO3 Ap/CaCO3 ) was fabricated through a dissolution-precipitation reaction using CaCO3 granules as a precursor to accelerate bone replacement based on superior osteoconductivity of the CO3 Ap shell, along with Ca2+ release from the CaCO3 core and quicker resorption of the CaCO3 core. In the present study, CaCO3 , 10% CO3 Ap/CaCO3 , 30% CO3 Ap/CaCO3 , and CO3 Ap granules were fabricated and examined histologically to evaluate their potential as bone substitutes. ...
Tópico(s): Dental Implant Techniques and Outcomes
2018 - Wiley | Journal of Tissue Engineering and Regenerative Medicine
Ryu‐ichiro Ohyama, M. Sakamoto, A Nagai,
2009 - Institute of Physics | Journal of Physics D Applied Physics
... of suffering, the author evaluates narratives such as Nagai Takashi’s providence ( go-setsuri ご摂理) and interpretation of the bombing as ...
Tópico(s): Korean Peninsula Historical and Political Studies
2016 - Brill | Journal of Religion in Japan
Hirokazu Nagai, Masako Kobayashi-Fujioka, Kenji Fujisawa, Go Ohe, Natsumi Takamaru, Kanae Hara, Daisuke Uchida, Tetsuya Tamatani, Kunio Ishikawa, Youji Miyamoto,
Tópico(s): 3D Printing in Biomedical Research
2015 - Springer Science+Business Media | Journal of Materials Science Materials in Medicine
Koumei Shirasuna, Takashi Shimizu, Ken‐Go Hayashi, K Nagai, Motozumi Matsui, Akio Miyamoto,
Luteolysis is caused by a pulsatile release of prostaglandin F(2alpha) (PGF(2alpha)) from the uterus in ruminants, and a positive feedback between endometrial PGF(2alpha) and luteal oxytocin (OXT) has a physiologic role in the promotion of luteolysis. The bovine corpus luteum (CL) produces vasoactive substances, such as endothelin 1 (EDN1) and angiotensin II (Ang II), that mediate and progress luteolysis. We hypothesized that luteal OXT has an additive function to ensure the CL regression with EDN1 and ...
Tópico(s): Veterinary Equine Medical Research
2007 - Oxford University Press | Biology of Reproduction
Go Harada, Toshitaka Nagai, Takasi Senba, Takashi Suzuki,
We study a system of parabolic equations introduced by E.F. Keller and L.A. Segel to describe the chemotactic feature of slime molds. Concentration toward the boundary is shown for the blowup solution with the total mass less than $8\pi$. For this purpose, a variant of the concentration lemma of Chang and Yang's type, and also a parabolic version of an inequality due to Brezis and Merle, are provided.
Tópico(s): Advanced Mathematical Modeling in Engineering
2001 - | Advances in Differential Equations
Go Ogiya, Daisuke Nagai, Tomoaki Ishiyama,
Primordial dark matter (DM) haloes are the smallest gravitationally bound DM structures from which the first stars, black holes, and galaxies form and grow in the early universe. However, their structures are sensitive to the free streaming scale of DM, which in turn depends on the nature of DM particles. In this work, we test the hypothesis that the slope of the central cusps in primordial DM haloes near the free streaming scale depends on the nature of merging process. By combining and analysing ...
Tópico(s): Dark Matter and Cosmic Phenomena
2016 - Oxford University Press | Monthly Notices of the Royal Astronomical Society
Kenichi Watanabe, Yuki Saito, Meilei Ma, Mir Imam Ibne Wahed, Yuichi Abe, Kenichi Hirabayashi, Gurusamy Narasimman, Juan Wen, Palaniyandi Suresh, Fadia E. Ali, Ken Shirai, Mayako Soga, Yusuke Nagai, Mikio Nakazawa, Go Hasegawa, Makoto Naito, Hitoshi Tachikawa, Makoto Kodama, Yoshifusa Aizawa, Kenichi Yamaguchi, Toshihiro Takahashi,
Angiotensin-converting enzyme inhibitors have been shown to reduce morbidity and mortality in patients with heart failure. The angiotensin type-1 blocking and cardioprotective properties of perindopril and enalapril were studied in a rat model of dilated cardiomyopathy after autoimmune myocarditis. Enalapril at 20 mg/kg showed the same angiotensin type-1 blocking action as perindopril at 2 mg/kg in rats with heart failure. Twenty-eight days after immunization, surviving Lewis rats (90/120 = 75%) were ...
Tópico(s): Viral Infections and Immunology Research
2003 - Lippincott Williams & Wilkins | Journal of Cardiovascular Pharmacology