E.A. Heredia, Gonzalo R. Arce,
The continuous threshold decomposition is a segmentation operator used to split a signal into a set of multilevel components. This decomposition method can be used to represent continuous multivariate piecewise linear (PWL) functions and, therefore, can be employed to describe PWL systems defined over a rectangular lattice. The resulting filters are canonical and have a multichannel structure that can be exploited for the development of rapidly convergent algorithms. The optimum design of the class ...
Tópico(s): Advanced Adaptive Filtering Techniques
1996 - Institute of Electrical and Electronics Engineers | IEEE Transactions on Signal Processing
Álvaro Fernández-Heredia, Gonzalo Fernández‐Sánchez,
The quality of urban life is based on sustainable mobility plans, and the bicycle is becoming increasingly important. This way of transport and its use result from a combination of urban policies, local movements, singularities of the context and social configurations. This article shows the extent to which mobility policy development and implementation models give room to pro-bike urban movements and to those who influence its promotion. It also shows the importance of citizen participation in ...
Tópico(s): Transportation Planning and Optimization
2019 - Elsevier BV | Case Studies on Transport Policy
S. Vila-Luna, S. Cabrera-Isidoro, L. Vila-Luna, Ismael Juárez, José L. Bata-García, Fernando J. Álvarez-Cervera, Rita Esther Zapata-Vázquez, Gloria Arankowsky‐Sandoval, Francisco J. Heredia-López, Gonzalo Flores, José L. Góngora‐Alfaro,
Chronic caffeine consumption has been inversely associated with the risk of developing dementia and Alzheimer's disease. Here we assessed whether chronic caffeine treatment prevents the behavioral and cognitive decline that male Wistar rats experience from young (≈3 months) to middle age (≈10 months). When animals were young they were evaluated at weekly intervals in three tests: motor activity habituation in the open field (30-min sessions at the same time on consecutive days), continuous spontaneous ...
Tópico(s): Tryptophan and brain disorders
2011 - Elsevier BV | Neuroscience
J. Linares‐Flores, José Antonio Juárez-Abad, Arturo Hernández‐Méndez, Omar Castro-Heredia, J. Fermi Guerrero‐Castellanos, Rubén Heredia-Barba, Gonzalo Curiel‐Olivares,
This article presents a new control strategy merging a sliding mode control (SMC) with a linear extended state observer (LESO) to regulate the output voltage of the buck–boost power converter system affected by matched and mismatched disturbances. The SMC–LESO schema uses the input–output linearization approach and the equivalent control method to determine the boundary layer around the sliding surface. This boundary layer depends on the sliding surface and the equivalent control value, depending ...
Tópico(s): Multilevel Inverters and Converters
2021 - Institute of Electrical and Electronics Engineers | IEEE Transactions on Industry Applications
Jorge Heredia, Cathy Rubiños, William Gonzalo Vega Salas, Walter Heredia, Alejandro Flores,
Organizations need to develop their resilience to foster future success to survive complex environments. This research conducts a comparative analysis to understand firms’ strategies in a “black swan” event. We use the “strategy tripod” to operationalize resilience theory and explain the configurations or pathways that lead to high organizational resilience in a crisis context. The data correspond to 1936 firms drawn from the “Enterprise Survey 2020 for Innovation and Entrepreneurship in China (ESIEC)”, ...
Tópico(s): Economic and Technological Innovation
2022 - Multidisciplinary Digital Publishing Institute | Sustainability
E.A. Heredia, Gonzalo R. Arce,
When nonlinear filters are designed based on input-output observations, the descriptive nonlinear transformation between the input and the output signals is often unknown. Filters with generalized models are therefore required for a good characterization of these cases. In this paper, we introduce a class of filters obtained from the additive combination of multiple kernels. Each kernel constitutes a localized model for the desired nonlinear mapping and is defined as a multivariate continuous piecewise ...
Tópico(s): Blind Source Separation Techniques
2000 - Institute of Electrical and Electronics Engineers | IEEE Transactions on Signal Processing
Natalia Quijada‐Morín, Ignacio García‐Estévez, Julio Nogales‐Bueno, Francisco J. Rodríguez‐Pulido, Francisco J. Heredia, Julián C. Rivas‐Gonzalo, M. Teresa Escribano-Bailón, José Miguel Hernández‐Hierro,
Grape seeds were collected in ten different dates and classified in seven groups according to their individual hyperspectral imaging characteristics. Proanthocyanidin composition was studied using HPLC-MS for oligomers and acid catalyzed cleavage for polymers characterization. The combination of both analysis provided a complete description of the flavanols. Chemometric analysis was performed to summarize the analytical results. None of the considered variables presented statistical differences ...
Tópico(s): Phytochemicals and Antioxidant Activities
2016 - Elsevier BV | Talanta
Cosme Alvarado‐Esquivel, Luis Francisco Sánchez-Anguiano, Jesús Hernández‐Tinoco, Agar Ramos-Nevárez, Sergio Estrada-Martínez, Sandra Margarita Cerrillo-Soto, Gonzalo Elías Medina-Heredia, Carlos Alberto Guido-Arreola, Araceli Alejandra Soto-Quintero, Isabel Beristáin-García,
Objectives This study was performed to determine the association between seropositivity to Toxoplasma gondii and a history of blood transfusion. Methods Patients who had undergone blood transfusion (n = 410) and age- and sex-matched controls who had not undergone blood transfusion (n = 1230) were examined for anti- T. gondii IgG and IgM antibodies using enzyme-linked immunoassays. Results Anti- T. gondii IgG antibodies were detected in 57 (13.9%) patients and in 129 (10.5%) controls with a borderline difference [ ...
Tópico(s): Travel-related health issues
2018 - SAGE Publishing | Journal of International Medical Research
Esther Luna Heredia, Gonzalo Peña, Julián Ruiz‐Galiana,
Tópico(s): Mechanics and Biomechanics Studies
2004 - Arán Ediciones | Nutrición Hospitalaria
Einar Thor Godínez Salas, Martha Guevara‐Cruz, Priscila Villanueva‐Luna, Maria del Rocio Guizar‐Heredia, Gonzalo M. Torres Villalobos, Edgar Pichardo Ontiveros, Guillermo Ordaz Nava, Ivan Torres Villalvazo, Nimbe Torres, Armando R. Tovar,
Background Obesity is a public health problem that has been linked to the development of insulin resistance (IR), which is defined as the inability of tissues to respond to the action of this hormone. The presence of IR is associated with lipotoxicity and a greater metabolic inflexibility. Experimental studies in rodents in our laboratory have shown that bioactive compounds (Resveratrol (R), Genistein (G)) can improve insulin sensitivity by the activation of AMPK in skeletal muscle (SM), increasing fatty ...
Tópico(s): Sirtuins and Resveratrol in Medicine
2017 - Wiley | The FASEB Journal
J.G. Gonzalez, E.A. Heredia, Tariq Rahman, Kenneth E. Barner, Gonzalo R. Arce,
Remote manually operated tasks such as those found in teleoperation, virtual reality, or joystick-based computer access, require the generation of an intermediate electrical signal which is transmitted to the controlled subsystem (robot arm, virtual environment, or a cursor in a computer screen). When human movements are distorted, for instance, by tremor, performance can be improved by digitally filtering the intermediate signal before it reaches the controlled device. This paper introduces a novel ...
Tópico(s): Teleoperation and Haptic Systems
2000 - Institute of Electrical and Electronics Engineers | IEEE Transactions on Biomedical Engineering
M. Teresa Escribano-Bailón, Marta Álvarez‐García, Julián C. Rivas‐Gonzalo, Francisco J. Heredia, Celestino Santos‐Buelga,
A pigment derived from the acetaldehyde-mediated condensation between (+)-catechin and malvidin 3-O-glucoside has been prepared and isolated by semipreparative HPLC, and its characteristics of color and stability have been studied and compared with that of malvidin glucoside in aqueous solutions. When the pH was increased from 2.2 to 5.5, the solution of the pigment became progressively more violet (lambda(max) = 560 nm at pH 5.5), whereas similar solutions of the anthocyanin were almost colorless at pH ...
Tópico(s): Tea Polyphenols and Effects
2001 - American Chemical Society | Journal of Agricultural and Food Chemistry
Matilde García-Marino, M. Luisa Escudero-Gilete, Francisco J. Heredia, M. Teresa Escribano-Bailón, Julián C. Rivas‐Gonzalo,
A study of the changes of copigmentation phenomenon in wines elaborated from different varieties has been undertaken. Colorimetric measurement of Tempranillo (T) and Graciano (G) monovarietal wines, and two 80:20 blend wines: M, (grape blending T and G, co-maceration) and W (wine blending T and G, co-vinification) was performed by spectrophotometry. Significant differences (p < 0.05) were found among the color of the wines. The Graciano cv. afforded somewhat darker and more colorful wines than the other ...
Tópico(s): Phytochemicals and Antioxidant Activities
2012 - Elsevier BV | Food Research International
Francisco J. Heredia, E. M. Francia-Aricha, Julián C. Rivas‐Gonzalo, Isabel M. Vicario, Celestino Santos‐Buelga,
Five anthocyanins (the 3-monoglucoside of delphinidin, cyanidin, petunidin, peonidin and malvidin), isolated from red grape skins, were subjected to a spectroscopic study to characterize their chromatic properties in a model solution imitating wine in the pH range 1.5–7.0. Tristimulus colorimetry (CIEXYZ, CIELUV and CIELAB colour spaces) proved to be a useful tool for the chromatic characterization of these anthocyanins. Significant colour differences were found among them, related to the number and ...
Tópico(s): Horticultural and Viticultural Research
1998 - Elsevier BV | Food Chemistry
Pedro Martínez-Paz, M. Fernandez Aragon, Esther Gómez‐Sánchez, Mario Lorenzo‐López, Estefanía Gómez‐Pesquera, R. López Herrero, Belén Sánchez-Quirós, Olga de la Varga-Martínez, Álvaro Tamayo-Velasco, Christian Ortega-Loubón, Emilio García‐Morán, Hugo Gonzalo‐Benito, María Heredia‐Rodríguez, Eduardo Tamayo,
Nowadays, mortality rates in intensive care units are the highest of all hospital units. However, there is not a reliable prognostic system to predict the likelihood of death in patients with postsurgical shock. Thus, the aim of the present work is to obtain a gene expression signature to distinguish the low and high risk of death in postsurgical shock patients. In this sense, mRNA levels were evaluated by microarray on a discovery cohort to select the most differentially expressed genes between ...
Tópico(s): Hemodynamic Monitoring and Therapy
2020 - Multidisciplinary Digital Publishing Institute | Journal of Clinical Medicine
... los más relevantes linajes del reino de Aragón, Gonzalo Fernández de Heredia se erigió como un personaje clave en su ...
Tópico(s): Historical Studies on Spain
2018 - University of Zaragoza | Aragón en la Edad Media
Huw Aled Lewis, Ian MacPherson, Ralph Penny,
... Coronica de los Conquiridores de Juan Fernandez de Heredia - problemas codilogicos y ecdoticos the theatricality of Celestina the language of Gonzalo de Berceo, in the context of peninsular dialectal ...
Tópico(s): Early Modern Spanish Literature
1999 - Modern Humanities Research Association | The Modern Language Review
Marta Martín-Fernández, R. Aller, María Heredia‐Rodríguez, Esther Gómez‐Sánchez, Pedro Martínez-Paz, Hugo Gonzalo‐Benito, Laura Sánchez-de Prada, Óscar Gorgojo, Irene Carnicero-Frutos, Eduardo Tamayo, Álvaro Tamayo-Velasco,
Oxidative stress may be a key player in COVID-19 pathogenesis due to its significant role in response to infections. A defective redox balance has been related to viral pathogenesis developing a massive induction of cell death provoked by oxidative stress. The aim of this study is to perform a complete oxidative stress profile evaluation regarding antioxidant enzymes, total antioxidant capacity and oxidative cell damage in order to characterize its role in diagnosis and severity of this disease.
Tópico(s): Long-Term Effects of COVID-19
2021 - Elsevier BV | Redox Biology
Gonzalo Fernández‐Sánchez, Álvaro Fernández-Heredia,
The sustainable mobility of the future comes about through sustainable ways of transport, such as walking, cycling, or collective transport. This includes the bus, the underground, and trains in big cities. This article reviews bus-related policies and initiatives worldwide. It also analyses ten cities looking at medium and long-term strategies for the urban bus service. The main ideas are: the forecasts for the use of the urban bus system indicate a significant increase in demand, therefore, there ...
Tópico(s): Urban Transport and Accessibility
2018 - Multidisciplinary Digital Publishing Institute | Sustainability
Tópico(s): Spanish Philosophy and Literature
2018 - Ediciones Universidad de Salamanca | Azafea Revista de Filosofía
Tópico(s): Cultural and Mythological Studies
2018 - Fondo de Cultura Económica | Revista de hispanismo filosófico
Tópico(s): Social Sciences and Policies
2018 - Ediciones Universidad de Salamanca | Azafea Revista de Filosofía
Ignacio Jausoro, Iván Mestres, Gonzalo Quassollo, Luján Masseroni, Florencia Heredia, Alfredo Cáceres,
IQGAP1 is a scaffolding protein that regulates spine number. We now show a differential role for IQGAP1 domains in spine morphogenesis, in which a region of the N-terminus that promotes Arp2/3-mediated actin polymerization and branching stimulates spine head formation while a region that binds to Cdc42 and Rac is required for stalk extension. Conversely, IQGAP1 rescues spine deficiency induced by expression of dominant negative Cdc42 by stimulating formation of stubby spines. Together, our observations ...
Tópico(s): Developmental Biology and Gene Regulation
2013 - Public Library of Science | PLoS ONE
María Jesús Cejudo‐Bastante, Bruno Rodríguez-Morgado, M. José Jara-Palacios, Julián C. Rivas‐Gonzalo, Juan Parrado, Francisco J. Heredia,
The effect of adding an enzymatic hydrolysate of grape seeds (EH-GS) during Syrah wine fermentation in a warm climate has been evaluated. We focused on the polyphenolic composition as well as the application of differential and tristimulus colorimetry to colour data. This is the first attempt at using this oenological alternative to avoid common colour losses of red wines elaborated in a warm climate. The addition of 250 g (simple dose, SW) of EH-GS to 120 kg of fermentation material promoted a significant ( ...
Tópico(s): Phytochemicals and Antioxidant Activities
2016 - Elsevier BV | Food Chemistry
Gema Miñana, Rafael de la Espriella, Patricia Palau, Pau Llácer, Eduardo Núñez, Enrique Santas, Ernesto Valero, Miguel Lorenzo, Gonzalo Núñez, Vicente Bodı́, Raquel Heredia, Juan Sanchís, Antoni Bayés‐Genís, Francisco J. Chorro, Julio Núñez,
We aimed to assess the association between CA125 and the long-term risk of total acute heart failure (AHF) admissions in patients with an index hospitalization with AHF and preserved ejection fraction (HFpEF). We prospectively included 2369 patients between 2008 and 2019 in three centers. CA125 and NT-proBNP were measured during early hospitalization and evaluated as continuous and categorized in quartiles (Q). Negative binomial regressions were used to assess the association with the risk of recurrent ...
Tópico(s): Diabetes Treatment and Management
2022 - Nature Portfolio | Scientific Reports
... principals”: Rafael Serra, José Martí, Sotero Figueroa, Gertrudis Heredia de Serra, Manuela Aguayo de Figueroa, Juan Gualberto Gómez, Juan and Gerónimo Bonilla, and Francisco Gonzalo “Pachín” Marín, Puerto Ricans and Cubans all and, ...
Tópico(s): Spanish Literature and Culture Studies
2020 - Duke University Press | Hispanic American Historical Review
J.G. Gonzalez, E.A. Heredia, Tariq Rahman, Kenneth E. Barner, Gonzalo R. Arce,
Remote manually operated tasks such as those found in teleoperation, virtual reality, or joystick-based computer access, require the generation of an intermediate signal which is transmitted to the controlled subsystem (robot arm, virtual environment or cursor). When man-machine movements are distorted by tremor, performance can be improved by digitally filtering the intermediate signal before it reaches the controlled device. This paper introduces a novel filtering framework in which digital equalizers ...
Tópico(s): Advanced Memory and Neural Computing
1995 - SPIE | Proceedings of SPIE, the International Society for Optical Engineering/Proceedings of SPIE
Belén Gordillo, Francisco J. Rodríguez‐Pulido, M. Lourdes Gonzalez‐Miret, Natalia Quijada‐Morín, Julián C. Rivas‐Gonzalo, Ignacio García‐Estévez, Francisco J. Heredia, M. Teresa Escribano-Bailón,
The combined effect of anthocyanin-flavanol-flavonol ternary interactions on the colorimetric and chemical stability of malvidin-3-glucoside has been studied. Model solutions with fixed malvidin-3-glucoside/(+)-catechin ratio (MC) and variable quercetin-3-β-d-glucoside concentration (MC+Q) and solutions with fixed malvidin-3-glucoside/quercetin-3-β-d-glucoside ratio (MQ) and variable (+)-catechin concentration (MQ+C) were tested at levels closer to those existing in wines. Color variations during storage ...
Tópico(s): Food Quality and Safety Studies
2015 - American Chemical Society | Journal of Agricultural and Food Chemistry
Enrique Santas, Patricia Palau, Pau Llácer, Rafael de la Espriella, Gema Miñana, Gonzalo Núñez‐Marín, Miguel Lorenzo, Raquel Heredia, Juan Sanchís, Francisco J. Chorro, Antoni Bayés‐Genís, Julio Núñez,
Background Following a heart failure (HF)‐decompensation, there is scarce data about sex‐related prognostic differences across left ventricular ejection fraction (LVEF) status. We sought to evaluate sex‐related differences in 6‐month mortality risk across LVEF following admission for acute HF. Methods and Results We retrospectively evaluated 4812 patients consecutively admitted for acute HF in a multicenter registry from 3 hospitals. Study end points were all‐cause, cardiovascular, and HF‐related ...
Tópico(s): Cardiac pacing and defibrillation studies
2021 - Wiley | Journal of the American Heart Association
Pedro Martínez-Paz, M. Fernandez Aragon, Esther Gómez‐Sánchez, Mario Lorenzo‐López, Estefanía Gómez‐Pesquera, A. Fadrique Fuentes, Pilar Liu, Álvaro Tamayo-Velasco, Christian Ortega-Loubón, Marta Martín-Fernández, Hugo Gonzalo‐Benito, Emilio García‐Morán, María Heredia‐Rodríguez, Eduardo Tamayo,
Objectives To obtain a gene expression signature to distinguish between septic shock and non-septic shock in postoperative patients, since patients with both conditions show similar signs and symptoms. Methods Differentially expressed genes were selected by microarray analysis in the discovery cohort. These genes were evaluated by quantitative real time polymerase chain reactions in the validation cohort to determine their reliability and predictive capacity by receiver operating characteristic ...
Tópico(s): Immune Response and Inflammation
2021 - Elsevier BV | Journal of Infection