Julián Aliste, Sebastián Layera, Daniela Bravo, Álvaro Jara, Gonzalo Muñoz, Cristián Barrientos, Rodrigo Wulf, Julián Brañez, Roderick J. Finlayson, De Q.H. Tran,
Background This randomized trial compared ultrasound-guided pericapsular nerve group block and suprainguinal fascia iliaca block in patients undergoing primary total hip arthroplasty. We selected the postoperative incidence of quadriceps motor block (defined as paresis or paralysis of knee extension) at 6 hours as the primary outcome. We hypothesized that, compared with suprainguinal fascia iliaca block, pericapsular nerve group block would decrease its occurrence from 70% to 20%. Methods Forty patients ...
Tópico(s): Nausea and vomiting management
2021 - BMJ | Regional Anesthesia & Pain Medicine
Constantino D. Dragicevic, Cristián Aedo, Alex León, Macarena Bowen, Natalia Cisterna Jara, Gonzalo Terreros, Luis Robles, Paul H. Délano,
In mammals, efferent projections to the cochlear receptor are constituted by olivocochlear (OC) fibers that originate in the superior olivary complex. Medial and lateral OC neurons make synapses with outer hair cells and with auditory nerve fibers, respectively. In addition to the OC system, there are also descending projections from the auditory cortex that are directed towards the thalamus, inferior colliculus, cochlear nucleus, and superior olivary complex. Olivocochlear function can be assessed ...
Tópico(s): Marine animal studies overview
2015 - Springer Science+Business Media | Journal of the Association for Research in Otolaryngology
Victoria B. Velásquez, Gabriel Zamorano, Jonathan Martínez-Pinto, Christian Bonansco, Pablo Jara, Gonzalo E. Torres, Georgina M. Renard, Ramón Sotomayor‐Zárate,
Neonatal programming with sex hormones produces long-term functional changes in various tissues, including the brain. Previously, we demonstrated a higher content of dopamine and an increase in potassium-induced dopamine release in the nucleus accumbens of adult rats exposed to estradiol valerate. On the other hand, sex hormones also affect the opioid system increasing the expression of the μ opioid receptor and β-endorphins. Here, we investigated if neonatal programming with sex hormones alters ...
Tópico(s): Neurotransmitter Receptor Influence on Behavior
2019 - Frontiers Media | Frontiers in Pharmacology
Alejandro Jara, Eduardo A. Undurraga, M. Cecilia Gonzalez Corcia, Fabio Paredes, Tomás Fontecilla, Gonzalo Jara, Alejandra Pizarro, Johanna Acevedo, Katherinne Leo, Francisco Cázares de León, Carlos Sans, Paulina Leighton, Pamela Suárez, Heriberto García-Escorza, Rafael Araos,
Mass vaccination campaigns to prevent coronavirus disease 2019 (Covid-19) are occurring in many countries; estimates of vaccine effectiveness are urgently needed to support decision making. A countrywide mass vaccination campaign with the use of an inactivated severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccine (CoronaVac) was conducted in Chile starting on February 2, 2021.We used a prospective national cohort, including participants 16 years of age or older who were affiliated with ...
Tópico(s): Vaccine Coverage and Hesitancy
2021 - Massachusetts Medical Society | New England Journal of Medicine
Julio Labra, Marcos Zúñiga, Javier Rebolledo, Mohamed A. Ahmed, Rodrigo Carvajal, Nicolás Jara, Gonzalo Carvajal,
Tópico(s): Identification and Quantification in Food
2023 - Elsevier BV | Aquacultural Engineering
Петер Келлер, John I. Koivula, Gonzalo Jara,
Tópico(s): Mineralogy and Gemology Studies
1985 - Gemological Institute of America | Gems & Gemology
Sergio Matarraz, Carlos Fernández, Manuel Albors, Cristina Teodósio, Antonio López, María Jara‐Acevedo, Carlos Cerveró, Gonzalo Caballero, Oliver Gutiérrez, Alberto Órfão,
Abstract Limited information is currently available about the proliferation activity and cell‐cycle distribution of different bone marrow (BM) cell subsets defined according to their lineage and maturation stage in normal versus cytopenia‐associated reactive BM samples. Here, we report a three‐color flow cytometry approach to investigate the cell‐cycle distribution of different BM cell compartments—CD34 + hematopoietic progenitor and precursor cells (HPC), maturing neutrophils and monocytic cells, mature ...
Tópico(s): Hematological disorders and diagnostics
2011 - Wiley | Cytometry Part B Clinical Cytometry
María Jesús Cejudo‐Bastante, Bruno Rodríguez-Morgado, M. José Jara-Palacios, Julián C. Rivas‐Gonzalo, Juan Parrado, Francisco J. Heredia,
The effect of adding an enzymatic hydrolysate of grape seeds (EH-GS) during Syrah wine fermentation in a warm climate has been evaluated. We focused on the polyphenolic composition as well as the application of differential and tristimulus colorimetry to colour data. This is the first attempt at using this oenological alternative to avoid common colour losses of red wines elaborated in a warm climate. The addition of 250 g (simple dose, SW) of EH-GS to 120 kg of fermentation material promoted a significant ( ...
Tópico(s): Phytochemicals and Antioxidant Activities
2016 - Elsevier BV | Food Chemistry
Patricio González‐Hormazábal, Álex Arenas, Carolina Serrano, Margarita Pizarro, Eduardo Fuentes‐López, Jorge Arnold, Zoltán Berger, Maher Musleh, H Valladares, Enrique Lanzarini, Lilian Jara, V. Gonzalo Castro, M. Constanza Camargo, Arnoldo Riquelme,
Treatments for Helicobacter pylori (H. pylori) eradication include the use of antibiotics and a proton-pump inhibitor. Antibiotic resistance is a major concern for two drugs: levofloxacin and clarithromycin. The aim was to determine the prevalence of levofloxacin resistance (LevoR) and clarithromycin resistance (ClaR) in an urban population in Santiago, Chile.Gastric mucosa biopsies were obtained for DNA isolation from 143 H. pylori-positive individuals aged 18-80 years. Direct sequencing of the quinolone- ...
Tópico(s): Microscopic Colitis
2021 - Elsevier BV | Archives of Medical Research
José Granell, Javier Gavilanes, Javier Herrero, Juan L. Sánchez-Jara, María José Martín Velasco, Gonzalo Martín,
Cost-effectivity of universal newborn hearing screening programmes is under constant review. In this context, the aim of the present study is to evaluate the performance of brainstem response audiometry (BERA) compared to otoacoustic emissions (OAE) as screening tools.Observational and retrospective study on a universal screening programme started in 1998. We perform a comparative analysis between two groups of newborns evaluated in consecutive periods of time. We analyze outcome measures of the programme ...
Tópico(s): Ear Surgery and Otitis Media
2008 - Elsevier BV | Acta Otorrinolaringologica (English Edition)
Produção Nacional
Revisado por pares
Mário Guevara, Guillermo F. Olmedo, Emma Stell, Yusuf Yiğini, Yameli Aguilar, Carlos Arellano Hernández, Gloria E. Arévalo, Carlos Eduardo Arroyo-Cruz, Adriana Bolívar, Sally Bunning, Nelson Bustamante Cañas, Carlos Omar Cruz-Gaistardo, Fabián Dávila, Martin Dell Acqua, Arnulfo Encina, Hernán Figueredo Tacona, F. C. Fontes, José Antonio Hernández-Herrera, Alejandro Navarro, Verónica Loayza, Alexandra M. Manueles, Fernando Mendoza Jara, Carolina Olivera, Rodrigo Osorio Hermosilla, Gonzalo Pereira, Pablo Viany Prieto, Iván A. Ramos, J.C. Rey Brina, Rafael Rivera, Javier Rodríguez‐Rodríguez, Ronald Roopnarine, Albán Rosales Ibarra, Kenset Amaury Rosales Riveiro, Guillermo Schulz, Adrian Spence, Gustavo M. Vasques, Rodrigo Vargas, Rodrigo Vargas,
Abstract. Country-specific soil organic carbon (SOC) estimates are the baseline for the Global SOC Map of the Global Soil Partnership (GSOCmap-GSP). This endeavor is key to explaining the uncertainty of global SOC estimates but requires harmonizing heterogeneous datasets and building country-specific capacities for digital soil mapping (DSM). We identified country-specific predictors for SOC and tested the performance of five predictive algorithms for mapping SOC across Latin America. The algorithms ...
Tópico(s): Soil Carbon and Nitrogen Dynamics
2018 - Copernicus Publications | SOIL
Ricardo Abejón, Jara Laso, María Margallo, Rubén Aldaco, Gonzalo Blanca-Alcubilla, Alba Bala, Pere Fullana–i–Palmer,
Food and beverage packaging represent a relevant fraction of municipal solid waste, and its adequate management is critical. Selective waste collection by an authorized organization according to an Extended Producer Responsibility System (EPRS) is the current option implemented in Spain for packaging. Other European countries have selected an alternative or a complement: a Deposit-Refund System (DRS) for certain type of beverage packaging. The selection of an EPRS or a DRS is a complex task and this ...
Tópico(s): Microplastics and Plastic Pollution
2020 - Elsevier BV | The Science of The Total Environment
Mohamed A. Ahmed, Jose Luis Gallardo, Marcos Zúñiga, Manuel A. Pedraza, Gonzalo Carvajal, Nicolás Jara, Rodrigo Carvajal,
Nowadays, conventional agriculture farms lack high-level automated management due to the limited number of installed sensor nodes and measuring devices. Recent progress of the Internet of Things (IoT) technologies will play an essential role in future smart farming by enabling automated operations with minimum human intervention. The main objective of this work is to design and implement a flexible IoT-based platform for remote monitoring of agriculture farms of different scales, enabling continuous ...
Tópico(s): IoT-based Smart Home Systems
2022 - Multidisciplinary Digital Publishing Institute | Sensors
Blanca Urzúa, Carolina Martínez, Ana Ortega‐Pinto, Daniela Adorno-Farías, Irene Morales‐Bozo, Gonzalo Riadi, Lilian Jara, Anita Plaza, Claudia Lefimil, Carla Lozano, Monserrat Reyes,
Amelogenesis imperfecta (AI) is a group of clinically and genetically heterogeneous inherited conditions, causing alterations in the structure of enamel and chemical composition of enamel matrix during development. The objective of this study was to compare the clinical, radiographic, histological and immunohistochemical phenotypes of subjects affected with hypocalcified AI from three Chilean families and identify causal mutations in the FAM83H gene.The diagnosis was made using clinical, radiographic, ...
Tópico(s): Periodontal Regeneration and Treatments
2015 - Elsevier BV | Archives of Oral Biology
Patricio González‐Hormazábal, Maher Musleh, Susana Escandar, H Valladares, Enrique Lanzarini, V. Gonzalo Castro, Lilian Jara, Zoltán Berger,
Current available treatments for Helicobacter pylori eradication are chosen according to local clarithromycin and metronidazole resistance prevalence. The aim of this study was to estimate, by means of molecular methods, both clarithromycin and metronidazole resistance in gastric mucosa from patients infected with H.pylori. A total of 191 DNA samples were analyzed. DNA was purified from gastric mucosa obtained from patients who underwent an upper gastrointestinal endoscopy at an university hospital ...
Tópico(s): Gastrointestinal disorders and treatments
2018 - BioMed Central | BMC Gastroenterology
Sandra Romero, Maher Musleh, Marco Bustamante, Juan Stambuk, R Pisano, Enrique Lanzarini, H Chiong, Jorge Rojas, V. Gonzalo Castro, Lilian Jara, Zoltán Berger, Patricio González‐Hormazábal,
Epithelial-mesenchymal transition (EMT) program has been linked as a driver of metastatic dissemination by conferring migratory and invasive capacity to cancer cells. Gastric cancer (GC) patients with tumors expressing altered levels of EMT markers have low survival. This study aimed to assess if polymorphisms of CDH1, TWIST1, SNAIL2, ZEB1 and ZEB2 genes are associated with survival in GC patients.A total of 153 individuals with diagnosis of GC were recruited in Santiago, Chile. All patients were ...
Tópico(s): Epigenetics and DNA Methylation
2018 - International Institute of Anticancer Research (IIAR) Conferences 1997. Athens, Greece. Abstracts | Anticancer Research
Patricio González‐Hormazábal, Maher Musleh, Marco Bustamante, Juan Stambuk, R Pisano, H Valladares, Enrique Lanzarini, H Chiong, Jorge Rojas, José Suazo, V. Gonzalo Castro, Lilian Jara, Zoltán Berger,
The RAS/RAF/MEK/ERK pathway regulates certain cellular functions, including cell proliferation, differentiation, survival, and apoptosis. Dysregulation of this pathway leads to the occurrence and progression of cancers mainly by somatic mutations. This study aimed to assess if polymorphisms of the RAS/RAF/MEK/ERK pathway are associated with gastric cancer. A case-control study of 242 gastric cancer patients and 242 controls was performed to assess the association of 27 single nucleotide polymorphisms ( ...
Tópico(s): Cancer Mechanisms and Therapy
2018 - Multidisciplinary Digital Publishing Institute | Genes
Patricio González‐Hormazábal, Sandra Romero, Maher Musleh, Marco Bustamante, Juan Stambuk, R Pisano, Enrique Lanzarini, H Chiong, Jorge Rojas, V. Gonzalo Castro, Lilian Jara, Zoltán Berger,
Inflammation is a key process in gastric carcinogenesis. Cytokines are mediators of inflammation and are involved in metastasis and tumorigenicity. We previously assessed the role of cytokine gene polymorphisms in gastric cancer risk in Chile. In the present study, we aimed to analyze whether these polymorphisms are associated with overall survival (OS) in gastric cancer (GC) patients.A total of 153 individuals with GC diagnosis were followed-up for at least 2 years. Hazard ratios (HR) were estimated ...
Tópico(s): Helicobacter pylori-related gastroenterology studies
2018 - International Institute of Anticancer Research (IIAR) Conferences 1997. Athens, Greece. Abstracts | Anticancer Research
Paolo Saona Hoffmann, Mauricio Jara‐Bertín, Gonzalo Moreno Warleta,
We analyze the extent to which firm size determines the relationship between growth opportunities and bank debt in the Chilean corporate sector. Using generalized method of moments (GMM) system estimator techniques in an unbalanced panel data of quoted firms, we provide evidence of a U-shaped relationship between growth opportunities and bank debt, which has a different behavior depending on the firm's size. Smaller firms seek private debt sooner than larger firms do when growth opportunities increase. ...
Tópico(s): Firm Innovation and Growth
2014 - Taylor & Francis | Emerging Markets Finance and Trade
Lilian Jara, Mónica L. Acevedo, Rafael Blanco, V. Gonzalo Castro, Teresa Bravo, Fernando Gómez, Enrique Waugh, O Peralta, Elsa Cabrera, José M. Reyes, Sandra Ampuero, Patricio González‐Hormazábal,
Tópico(s): Genetic factors in colorectal cancer
2007 - Elsevier BV | Cancer Genetics and Cytogenetics
Cristina Jiménez, María Jara‐Acevedo, Luís A. Corchete, David Castillo, Gonzalo R. Ordóñez, María Eugenia Sarasquete, Noemí Puig, Joaquín Martínez‐López, Isabel Prieto-Conde, María García‐Álvarez, Carmen Chillón, Ana Balanzategui, Miguel Alcoceba, Albert Oriol, Laura Rosiñol, Luis Palomera, Ana Isabel Teruel, Juan José Lahuerta, Joan Bladé, María‐Victoria Mateos, Alberto Órfão, Jesús F. San Miguel, Marcos González, Norma C. Gutiérrez, Ramón García‐Sánz,
Identification and characterization of genetic alterations are essential for diagnosis of multiple myeloma and may guide therapeutic decisions. Currently, genomic analysis of myeloma to cover the diverse range of alterations with prognostic impact requires fluorescence in situ hybridization (FISH), single nucleotide polymorphism arrays, and sequencing techniques, which are costly and labor intensive and require large numbers of plasma cells. To overcome these limitations, we designed a targeted-capture ...
Tópico(s): Glycosylation and Glycoproteins Research
2016 - Elsevier BV | Journal of Molecular Diagnostics
María C. García‐Hidalgo, Jessica González, Iván D. Benítez, Paola Carmona, Sally Santisteve, Manel Perez‐Pons, Anna Moncusí‐Moix, Clara Gort‐Paniello, Fátima Rodríguez‐Jara, Marta Molinero, Thalía Belmonte, Gerard Torres, Gonzalo Labarca, Estefanía Nova‐Lamperti, Jesús Caballero, Jesús F. Bermejo-Martín, Adrián Ceccato, Laia Fernández‐Barat, Ricard Ferrer, Dario García-Gasulla, Rosario Menéndez, Ana Motos, Óscar Peñuelas, Jordi Riera, Antoní Torres, Ferrán Barbé, David de Gonzalo‐Calvo,
There is a limited understanding of the pathophysiology of postacute pulmonary sequelae in severe COVID-19. The aim of current study was to define the circulating microRNA (miRNA) profiles associated with pulmonary function and radiologic features in survivors of SARS-CoV-2-induced ARDS. The study included patients who developed ARDS secondary to SARS-CoV-2 infection (n = 167) and a group of infected patients who did not develop ARDS (n = 33). Patients were evaluated 3 months after hospital discharge. ...
Tópico(s): COVID-19 Clinical Research Studies
2022 - Taylor & Francis | Emerging Microbes & Infections
Manuel López‐Santamaría, L Martínez, Loreto Hierro, M Gámez, J Murcia, C. Camarena, A. de la Vega, E. Frauca, Paloma Jara, M. Díaz, Teresa Berrocal, C. Prieto, Gonzalo Garzón, Juan A. Tovar,
The aim of this study was to review the biliary complications occurring in late follow-up after liver transplantation in children.The medical records of 135 children who received orthotopic liver transplantations (OLT) and had graft survival of more than 1 year were reviewed. Technical variants using a reduced-size graft were applied in 32 (23.7%). For biliary reconstruction, 15 patients had choledochocholedochostomy and 120 a Roux-en-Y loop. Biliary reoperation in the early post-OLT period was needed ...
Tópico(s): Congenital Anomalies and Fetal Surgery
1999 - Elsevier BV | Journal of Pediatric Surgery
Daniela Bravo, Sebastián Layera, Julián Aliste, Álvaro Jara, Diego Fernández, Cristián Barrientos, Rodrigo Wulf, Gonzalo Muñoz, Roderick J. Finlayson, De Q.H. Tran,
Comparison of ultrasound-guided lumbar plexus block (LPB) and suprainguinal fascia iliaca block (SIFIB) in patients undergoing total hip arthroplasty (THA). Randomized equivalence trial. University Hospital. Sixty patients undergoing primary THA. Patients were randomly allocated to receive ultrasound-guided LPB (n = 30) or SIFIB (n = 30). The local anesthetic agent (40 mL of levobupivacaine 0.25% with epinephrine 5 μg/mL) and block adjuvant (4 mg of intravenous dexamethasone) were identical in all subjects. ...
Tópico(s): Anesthesia and Sedative Agents
2020 - Elsevier BV | Journal of Clinical Anesthesia
Reseña del libro: Berríos, Claudio; Gonzalo Jara (eds.). Contrapuntos Latinoamericanos II: ensayos sobre una perspectiva continental. Valparaíso: Inubicalistas/Voces Opuestas, 2022
Tópico(s): Cultural and Social Studies in Latin America
2023 - CIG Media Group | Latinoamérica Revista de Estudios Latinoamericanos
Pablo Fresia, Ronald Jara, Rafael Tojo Sierra, Ignacio Ferrés, Gonzalo Greif, Gregorio Iraola, Luis Collado,
Abstract Background Helicobacter valdiviensis is a recently described enterohepatic species isolated from wild bird's fecal samples. Currently, its pathogenic potential and clinical significance are unknown mainly due to the lack of whole‐genome sequences to compare with other helicobacters and the absence of specific screenings to determine its prevalence in humans. Materials and Methods The species type strain ( WBE 14 T ) was whole‐genome‐sequenced, and comparative analyses were carried out including ...
Tópico(s): Viral gastroenteritis research and epidemiology
2017 - Wiley | Helicobacter
Javier Guerra Casanova, Carmen Sánchez Ávila, Alberto de Santos Sierra, Gonzalo Bailador del Pozo, Vicente Jara Vera,
In this article an in-air signature biometric technique is proposed. Users would authenticate themselves by performing a 3-D gesture invented by them holding a mobile device embedding an accelerometer. All the operations involved in the process are carried out inside the mobile device, so no additional devices or connections are needed to accomplish this task. In the article, 34 different users have invented and repeated a 3-D gesture according to the biometric technique proposed. Moreover, three ...
Tópico(s): Hand Gesture Recognition Systems
2010 - Springer Science+Business Media | Communications in computer and information science
José Granell, Javier Gavilanes, Javier Herrero, Juan L. Sánchez-Jara, María José Martín Velasco, Gonzalo Martín,
La relación coste-efectividad de los programas de cribado universal de la hipoacusia infantil es objeto de una constante revisión. En este contexto, el objetivo del presente trabajo es valorar el rendimiento de los potenciales evocados auditivos de tronco cerebral (PEATC) frente a las emisiones otoacústicas (EOA) como prueba de cribado. Estudio observacional retrospectivo sobre un programa de cribado universal iniciado en 1998. Realizamos un análisis comparativo entre dos grupos de recién nacidos ...
Tópico(s): Vestibular and auditory disorders
2008 - Elsevier BV | Acta Otorrinolaringológica Española
Patricio González‐Hormazábal, Diana Peláez, Maher Musleh, Marco Bustamante, Juan Stambuk, R Pisano, H Valladares, Enrique Lanzarini, H Chiong, José Suazo, Luis A. Quiñones, Nelson Varela, V. Gonzalo Castro, Lilian Jara, Zoltán Berger,
Helicobacter pylori is detected by pathogen recognition receptors including toll-like receptors (TLR) and nucleotide-binding oligomerization domain (NOD)-like receptors, eliciting an innate immune response against this bacteria. The aim of this study was to assess if polymorphisms of TLR2, TLR4, TLR5, NOD1 and NOD2 genes are associated with gastric cancer, in particular in individuals infected with H. pylori.A case-control study of 297 gastric cancer patients and 300 controls was performed to assess ...
Tópico(s): Veterinary medicine and infectious diseases
2021 - BioMed Central | Biological Research
Howard E. Gendelman, R. Lee Mosley, Michael D. Boska, JoEllyn McMillan,
... and brain cancerJohanna Catalan-Figueroa, Sujey Palma-Florez, Gonzalo Alvarez, Hans F Fritz, Miguel O Jara & Javier O Morales11 December 2015 | Nanomedicine, Vol. 11, ...
Tópico(s): Neurological disorders and treatments
2014 - Future Medicine | Nanomedicine