Angeles Castro, José M. Miguel del Corral, Marina Gordaliza, Concepción Grande, Antonia Gómez-Zurita, Dolores Garcı́a-Grávalos, Arturo San Feliciano,
Tópico(s): Biological Activity of Diterpenoids and Biflavonoids
2003 - Elsevier BV | European Journal of Medicinal Chemistry
Benedicto Jiménez, Marı́a Concepción Grande, Josefa Anaya, Pascual Torres, M. Grandé,
Four new coumarins, (+)-senecioylprangol, (−)-3′-senecioyloxymarmesin, (+)-3′-hydroxyprantschimgin and (+)-2″-senecioyloxymarmesin, besides 12 known coumarins have been isolated from two Ferulago species. Their structures have been established by spectroscopic methods and partial synthesis. New synthetic 3′-oxocoumarins are also described. There is a remarkable difference in the contents of the most abundant coumarins found in the roots of both species: osthol and aurapten are specific to F. capillaris and F. brachyloba, ...
Tópico(s): Advanced Synthetic Organic Chemistry
2000 - Elsevier BV | Phytochemistry
Pascual Torres, Concepción Grande, Josefa Anaya, M. Grandé,
Jacaranone (1), the related new dimethoxy derivative 2, and known triterpenoids were isolated from the aerial parts of Senecio minutus. The aerial parts and the rhizomes of Senecio boissieri afforded the furanoeremophilanes 3 and 4 and known triterpenoids.
Tópico(s): Sesquiterpenes and Asteraceae Studies
2000 - Elsevier BV | Fitoterapia
Pascual Torres, Juan H. Ayala, Concepción Grande, Josefa Anaya, M. Grandé,
The aerial parts of Senecio flavus contain besides known eremophilane derivatives, four new furanoeremophilanes oxidized at C-3 and a new eremophilenone lactam. The rhizomes of the plant also contain the same ketoeremophilenes found in the aerial parts and a new epoxyeremophilanolide. The structure of these compounds has been established by spectroscopic methods.
Tópico(s): Sesquiterpenes and Asteraceae Studies
1999 - Elsevier BV | Phytochemistry
Pascual Torres, Juan H. Ayala, Concepción Grande, Maria J. Macías, M. Grandé,
The roots of Senecio auricula var. major yielded, in addition to known compounds, four new eremophilane derivatives: the furanoeremophilanes 6β-(2-methylbutyryloxy)-10αH-furanoeremophilan-1-one, 6β-isobutyryloxysenberginone, 6β-(2-methylbutyryloxy)-senberginone and the bakkenolide 11β,12β-epoxy-6β-(2-methylbutyryloxy)-Δ1(10)-7-epidihydrobakkenolide A (senauricolide). Alkaline hydrolysis of senberginone esters gave, apart from the expected alcohols, the isomeric new 1β-hydroxy-10βH-furanoremophilan- ...
Tópico(s): Sesquiterpenes and Asteraceae Studies
1998 - Elsevier BV | Phytochemistry
M.P. Maqua, A.C.G. Vines, Esther Caballero, Marı́a Concepción Grande, Manuel Medarde, I.S. Bellido,
Apart from other already known components, two-eudesmane-type alcohols, two coumarins and a new spiroketalenolether-type acetylene were isolated from S. rosmarinifolia, subspp. rosmarinifolia and canescens. The structures assigned were based on their spectral properties. The relative stereochemistries of the new acetylene at C-11 and that of the known spiranic acetylenes were assigned by NMR-NOE experiments.
Tópico(s): Biological Activity of Diterpenoids and Biflavonoids
1988 - Elsevier BV | Phytochemistry
... de los problemas de las ciudades es la concepción de grandes proyectos urbanos que son ideados bajo políticas con ...
Tópico(s): Public Health and Environmental Issues
2016 - Catholic University of Colombia | Revista de Arquitectura
... foundress of the new convent of La Purísima Concepción (San Miguel el Grande) and her abbesses struggled to ensure that their ... during this period, the convent of La Purísima Concepción, founded in 1754 in San Miguel el Grande. The vida común reforms did not directly affect ...
Tópico(s): Latin American history and culture
2005 - Duke University Press | Hispanic American Historical Review
Magdalena Ahumada, Elisa Ansoleaga, Álvaro Castillo‐Carniglia,
... metropolitanas do Chile (Grande Santiago, Grande Valparaíso e Grande Concepción) selecionados ao acaso, em três etapas (quarteirão, unidades ...
Tópico(s): Occupational Health and Safety Research
2021 - Escola Nacional de Saúde Pública, Fundação Oswaldo Cruz | Cadernos de Saúde Pública
Concepción Violán, Gonzalo Grandes Odriozola, Edurne Zabaleta‐del‐Olmo, Enrique Gavilán Moral,
La atención primaria de salud ofrece grandes oportunidades para la investigación. Constituye un área de conocimiento propio, que es necesario desarrollar para mejorar la calidad de sus servicios y la salud de los pacientes. Estas oportunidades son únicas para la investigación clínica de base poblacional, con un enfoque de promoción de la salud y de prevención de la enfermedad, ya sea primaria, secundaria o terciaria. Es prioritario investigar en el desarrollo del modelo biopsicosocial de atención, ...
Tópico(s): Healthcare cost, quality, practices
2011 - Elsevier BV | Gaceta Sanitaria
Pablo Concepcion-Grande, A. González, Eva Chamorro, José Miguel Cleva, José Alonso, José A. Gómez‐Pedrero,
The purpose of this study is to determine if there is any correlation between the characteristics of the user’s eye movements (EMs) and the preference of the user when wearing different Progressive power lenses (PPLs) distributions. An eye-tracker system with a sample rate of 120Hz and temporal resolution of 8.3ms (Tobii-X3-120) was used to register EMs of 38 PPL users when reading in a computer screen with 2 types of PPLs (PPL-soft and PPL-hard). Number of fixations, complete fixation time, fixation ...
Tópico(s): Ophthalmology and Visual Impairment Studies
2022 - Bern Open Publishing | Journal of Eye Movement Research
R. Rial‐Otero, B. Cancho-Grande, Concepción Pérez Lamela, Jesús Simal‐Gándara, Manuel Arias‐Estévez,
A method based on solid-phase extraction (on silica cartridges) and high-performance liquid chromatography (HPLC) followed by diode array UV detection is presented as an analytical tool for screening diquat (DQ) and paraquat (PQ) in drinking waters. The method is useful for quality control laboratories of water companies and beverage industries. Absolute recoveries of DQ and PQ from drinking water (25 mL in all cases), spiked at levels between 0.1, 1.0, and 5.0 µg/L, range from 91% to 103%. Relative ...
Tópico(s): Microfluidic and Capillary Electrophoresis Applications
2006 - Oxford University Press | Journal of Chromatographic Science
Pablo Fuentes Retamal, Leonel Pérez,
La consolidación de la
Tópico(s): Latin American Urban Studies
2012 - University of Concepción | Atenea
Hugo Capellà Miternique, Pascale Marcotte,
... sont pas construites de toutes pièces pour eux. Concepción, la deuxième plus grande ville du Chili, est un bel exemple de ...
Tópico(s): Urbanism, Landscape, and Tourism Studies
2014 - | Téoros Revue de recherche en tourisme
Carlos E. Castano, A. Ortíz Sánchez, J. A. Grande, Concepción Paz,
Tópico(s): Refrigeration and Air Conditioning Technologies
2007 - | SAE technical papers on CD-ROM/SAE technical paper series
Marta Álvarez, Clara Benedí‐García, Pablo Concepcion-Grande, Paulina Dotor, A González González, Eva Chamorro, José Miguel Cleva,
Early detection and treatment of refractive defects during school age are essential to avoid irreversible future vision loss and potential school problems. Previously, vision screening of preschool children used methods based on subjective visual acuity; however, technologies such as photorefraction have promoted the detection of refractive errors quickly and easily. In this study, 1347 children from 10 schools in Madrid aged 4 to 12 years participated in a program of early detection of visual problems, ...
Tópico(s): Retinal Diseases and Treatments
2022 - Multidisciplinary Digital Publishing Institute | International Journal of Environmental Research and Public Health
Mariagiulia Dal Cero, Marta Román, Luís Grande, María Concepción Yárnoz Irazábal, Fernando Estremiana, Amaia Gantxegi, Clara Codony, Yanina Gobbini, Elisenda Garsot, Dulce Momblán, Marta González, Alexis Luna, Noelia Pérez, Aurora Aldeano, Sonia Fernández, Carles Olona, Judit Hermoso, Laura Pulido, J.J. Sánchez-Cano, Mercè Güell, David Salazar, Marta Gimeno, Manuel Pera,
The concept of textbook outcome (TO) has been proposed for analyzing quality of surgical care. This study assessed the incidence of TO among patients undergoing curative gastric cancer resection, predictors for TO achievement, and the association of TO with survival.All patients with gastric and gastroesophageal junction cancers undergoing curative gastrectomy between January 2014-December 2017 were identified from a population-based database (Spanish EURECCA Registry). TO included: macroscopically ...
Tópico(s): Colorectal Cancer Screening and Detection
2021 - Elsevier BV | European Journal of Surgical Oncology
Concepción González‐Palacios, JM Fregeneda-Grandes, José‐Miguel Aller‐Gancedo,
Abstract The probiotic activity of 15 bacterial isolates that inhibit Saprolegnia parasitica in vitro was tested for the biocontrol of saprolegniosis in rainbow trout ( Oncorhynchus mykiss Walbaum), adding the bacteria to tank water for 14 days at a concentration of 10 6 bacteria ml −1 water. Pseudomonas fluorescens LE89 and Pseudomonas fluorescens LE141 were effective in controlling experimental infection with S. parasitica since of the fish treated with LE89, 24.5% ± 16.27% ( p < 0.05) became infected, ...
Tópico(s): Myxozoan Parasites in Aquatic Species
2018 - Wiley | Journal of Fish Diseases
MT Carbajal-González, JM Fregeneda-Grandes, Concepción González‐Palacios, J.M. Aller-Gancedo,
Biological control of saprolegniosis with bacteria might be an alternative to the use of chemical compounds. Among criteria for the selection of such bacteria are their absence of pathogenicity to fish and their ability to prevent adhesion of the pathogen to the skin mucus. The pathogenicity to rainbow trout of 21 bacterial isolates with in vitro inhibitory activity against Saprolegnia parasitica was studied. Fifteen of the isolates, identified as Aeromonas sobria, Pantoea agglomerans, Pseudomonas ...
Tópico(s): Parasite Biology and Host Interactions
2013 - Inter-Research | Diseases of Aquatic Organisms
Pablo Concepcion-Grande, Eva Chamorro, José Miguel Cleva, José Alonso, José A. Gómez‐Pedrero,
Due to the lack of sensitivity of visual acuity (VA) measurement to quantify differences in visual performance between progressive power lenses (PPLs), in this study, we propose and evaluate an eye-tracking-based method to assess visual performance when wearing PPLs. A wearable eye-tracker system (Tobii-Pro Glasses 3) recorded the pupil position of 27 PPL users at near and distance vision during a VA test while wearing three PPL designs: a PPL for general use (PPL-Balance), a PPL optimized for near ...
Tópico(s): Tactile and Sensory Interactions
2023 - Multidisciplinary Digital Publishing Institute | Applied Sciences
Pablo Concepcion-Grande, Eva Chamorro, José Miguel Cleva, José Alonso, José A. Gómez‐Pedrero,
Objective The purpose of this study is to evaluate reading time and characteristics of fixations at different distances when looking through different areas of progressive power lenses (PPL) with different power distributions by means of eye-tracking technology. Method A wearable eye tracker system (Tobii-Pro Glasses 3) was used to record the pupil position of 28 PPL subjects when reading at near and distance vision while using 3 different PPL designs: a PPL optimized for distance vision (PPL-Distance), ...
Tópico(s): Ergonomics and Musculoskeletal Disorders
2023 - Public Library of Science | PLoS ONE
Johannes Delgado‐Ospina, Carlos David Grande‐Tovar, Juan Carlos Menjívar Flores, Manuel Salvador Sánchez Orozco,
The composition of essential oils extracted from plants can present great variability, even between individuals of the same species due to different conditions, such as extraction methods, climate and soil composition, among others.Most methods available for the determination of essential oil composition, such as gas chromatography-mass spectrometry (GC/MS), are expensive and time consuming, which prevents farmers or producers from determining the true value of their product or performing in-line ...
Tópico(s): Essential Oils and Antimicrobial Activity
2016 - University of Concepción | Chilean journal of agricultural & animal science
Albert Oriol, Susana Vives, Jesús María Hernández‐Rivas, Mar Tormo, I. Heras, C Rivas, Concepción Bethencourt, Federico Moscardó, Joan Pijoan, Carlos Grande, Eloy del Potro, R. Guardia, Salut Brunet, Juan Bergua, Teresa Bernal, M.J. Donáte Moreno, Carlota Calvo, Pilar Bastida, Evarist Feliú, Josep‐María Ribera,
Background About one half of adults with acute lymphoblastic leukemia are not cured of the disease and ultimately die. The objective of this study was to explore the factors influencing the outcome of adult patients with relapsed acute lymphoblastic leukemia.Design and Methods We analyzed the characteristics, the outcome and the prognostic factors for survival after first relapse in a series of 263 adult patients with acute lymphoblastic leukemia (excluding those with mature B-cell acute lymphoblastic ...
Tópico(s): Chronic Myeloid Leukemia Treatments
2010 - Ferrata Storti Foundation | Haematologica
... y, muy en particular, sobre Gregorio Mayans, cuya concepción de la religiosidad tenía grandes afinidades con la del Biliotecario de Modena. Antonio ...
Tópico(s): Libraries, Manuscripts, and Books
1997 - University of Alicante | Revista de Historia Moderna
JM Fregeneda-Grandes, Concepción González‐Palacios, Tania Pérez, Daniel Padilla, F. Real, José‐Miguel Aller‐Gancedo,
Previous studies have demonstrated that the strains Enterococcus gallinarum L1, Vagococcus fluvialis L21 and Lactobacillus plantarum CLFP3 are probiotics against vibriosis or lactococosis in sea bass or rainbow trout. In this study, the utility of these bacterial strains in the control of saprolegniosis was evaluated. For this purpose, both in vitro inhibition studies and competition for binding sites against Saprolegnia parasitica and in vivo tests with experimentally infected rainbow trout were ...
Tópico(s): Aquaculture Nutrition and Growth
2023 - Multidisciplinary Digital Publishing Institute | Animals
Gemma Tur, Santos Urbina Ramírez,
... una profunda revision teorica en torno a la concepcion de e-portafolio sustentada, resultando siete criterios, agrupados en tres grandes apartados: la estructura del eportafolio, los elementos de ...
Tópico(s): Educational Technology in Learning
2016 - University of Seville | Pixel-Bit Revista de Medios y Educación
... en Chile, en torno a la ciudad de Concepción, parecía confirmarla de manera absoluta. Al igual que el Norte Grande con el salitre y el cobre, esta zona ...
Tópico(s): Political and Social Dynamics in Chile and Latin America
2012 - Duke University Press | Hispanic American Historical Review
Josep‐María Ribera, Albert Oriol, Miguel Á. Sanz, Mar Tormo, Pascual Fernández, Eloy del Potro, Eugenia Abellá, Javier Bueno, Ricardo Parody, Pilar Bastida, Carlos Grande, Inmaculada Heras, Concepción Bethencourt, Evarist Feliú, Juan-José Ortega,
Retrospective studies have shown that adolescents and young adults with acute lymphoblastic leukemia (ALL) treated with pediatric protocols have better outcomes than similarly aged patients treated with adult protocols, but prospective studies comparing adolescents and young adults using pediatric schedules are scarce. The ALL-96 protocol was addressed to compare the toxicity and results of a pediatric-based protocol in adolescents (age 15-18 years) and young adults (age 19-30 years) with standard- ...
Tópico(s): Lymphoma Diagnosis and Treatment
2008 - Lippincott Williams & Wilkins | Journal of Clinical Oncology
A.J. Foppiano, E. Ovalle, K. Bataille, M. V. Stepanova,
... primero las observaciones de la foF2 hechas sobre Concepción (36.8°S; 73.0°W), antes de los dos grandes terremotos de Chile del 21 y 22 de ...
Tópico(s): earthquake and tectonic studies
2008 - National Autonomous University of Mexico | Geofísica Internacional
... fácil obtener una eficiente transmisión óptica dadas las grandes distancias que se encuentran en una concepción multimegawatt. En función de la ubicación del heliostato la distancia de transmisión puede variar desde algunos cientos a miles de pies. Las condiciones de diseño que influyen la transmisión óptica en estas grandes distancias son: Orientación precisa del heliostato; la dispersión ...
Tópico(s): solar cell performance optimization
1977 - Elsevier BV | Solar Energy