Guilherme Dias de Melo, Florian Sonthonnax, Gabriel Lepousez, Grégory Jouvion, Andrea Minola, Fabrizia Zatta, Florence Larrous, Lauriane Kergoat, Camille Mazo, Carine Moigneu, Roberta Aiello, Angela Salomoni, Élise Brisebard, Paola De Benedictis, Davide Corti, Hervé Bourhy,
... of two human monoclonal antibodies cures symptomatic rabies Guilherme Dias de Melo Guilherme Dias de Melo orcid.org/0000-0003-0747-7760 ... France Search for more papers by this author Guilherme Dias de Melo Guilherme Dias de Melo orcid.org/0000-0003-0747-7760 ... for more papers by this author Author Information Guilherme Dias de Melo1,‡, Florian Sonthonnax1,2,‡, Gabriel Lepousez3, Grégory ...
Tópico(s): Poxvirus research and outbreaks
2020 - Springer Nature | EMBO Molecular Medicine
Guilherme Dias de Melo, Françoise Lazarini, Florence Larrous, Lena Feige, Étienne Kornobis, Sylvain Levallois, Agnès Marchio, Lauriane Kergoat, David Hardy, Thomas Cokelaer, Pascal Pineau, Marc Lecuit, Pierre‐Marie Lledo, Jean‐Pierre Changeux, Hervé Bourhy,
... outcomes during SARS-CoV-2 infection by ivermectin Guilherme Dias de Melo Guilherme Dias de Melo orcid.org/0000-0003-0747-7760 ... France Search for more papers by this author Guilherme Dias de Melo Guilherme Dias de Melo orcid.org/0000-0003-0747-7760 ... for more papers by this author Author Information Guilherme Dias Melo1, Françoise Lazarini2, Florence Larrous1, Lena Feige1, Etienne ...
Tópico(s): COVID-19 and Mental Health
2021 - Springer Nature | EMBO Molecular Medicine
Produção Nacional
Revisado por pares
Heyder Pereira Neves, Gabriel Max Dias Ferreira, Guilherme Max Dias Ferreira, Leandro Rodrigues de Lemos, Guilherme Dias Rodrigues, Versiane Albis Leão, Aparecida Barbosa Mageste,
The rare earth elements, a group of metals consisting of the lanthanide series, together with yttrium and scandium, are increasingly important in high technology industries worldwide. Given the need to expand production of these elements, there is a search for processes to obtain them that are less environmentally damaging, since the rare earths production chain is associated with several environmental problems and concerns. Solvent extraction, one of the important steps involved in the obtaining ...
Tópico(s): Radioactive element chemistry and processing
2021 - Elsevier BV | Separation and Purification Technology
Produção Nacional
Revisado por pares
Héctor Azpúrua, Adriano M. C. Rezende, Guilherme Potje, Gilmar Pereira da Cruz Júnior, Rafael Fernandes, Victor R. F. Miranda, Levi Welington de Resende Filho, Jacó Dias Domingues, Filipe Augusto Santos Rocha, Frederico Luiz Martins de Sousa, Luiz Guilherme Dias de Barros, Erickson R. Nascimento, Douglas G. Macharet, Gustavo Pessin, Gustavo Freitas,
Tópico(s): Modular Robots and Swarm Intelligence
2021 - Springer Science+Business Media | Journal of Intelligent & Robotic Systems
Produção Nacional
Revisado por pares
Sílvia Juliana Barros e Silva, Gabriel Max Dias Ferreira, Leandro Rodrigues de Lemos, Guilherme Dias Rodrigues, Aparecida Barbosa Mageste,
The study of aqueous two-phase systems (ATPSs) formed by ionic liquids based on the choline cation and nonionic surfactants has received attention in recent years because of the biodegradability and nontoxicity of their components. In this work, liquid–liquid equilibrium data were obtained for ATPSs composed of Triton X (Triton X-100, Triton X-165, and Triton X-305), choline chloride, and water, at 298.15, 313.15, and 328.15 K. In general, these systems presented a top phase rich in choline chloride ...
Tópico(s): Crystallization and Solubility Studies
2019 - American Chemical Society | Journal of Chemical & Engineering Data
Produção Nacional
Revisado por pares
Gabriella Alexandre Borges, Gabriel Max Dias Ferreira, Kisla P.F. Siqueira, Anderson Dias, Keirom Osmany Nàjera Navarro, Sílvia Juliana Barros e Silva, Guilherme Dias Rodrigues, Aparecida Barbosa Mageste,
An evaluation was made of the use of MgAl-LDH with incorporated nitroprusside as an adsorbent to remove inorganic arsenic (As(III) and As(V)) and organic arsenic (DMA) from aqueous matrices. The material was synthesized by the co-precipitation method at constant pH and was characterized by Raman spectroscopy, infrared spectroscopy, thermogravimetry, X-ray diffraction, and high-resolution transmission electron microscopy, before and after use in the adsorption process. The effects on adsorption of ...
Tópico(s): Clay minerals and soil interactions
2020 - Elsevier BV | Journal of Colloid and Interface Science
Produção Nacional
Revisado por pares
Luiz Simeão do Carmo, Ricardo Souza Dias, Valter R. Linardi, Maria José de Sena, Deise Aparecida dos Santos, M Eduardo de Faria, Eronilda Castro Pena, Marti Jett, Luíz Guilherme Dias Heneine,
In February and May of 1999, the sanitary services of the Health Board in the cities of Manhuaçu and Passa-Quatro, Minas Gerais, Brazil, were notified of two food poisoning outbreaks involving a total of 378 individuals. In the first outbreak, 50 individuals became ill after eating Minas cheese. The symptoms of food poisoning (diarrhoea, vomiting, dizziness, chills, and headaches) appeared within 2 h of the individuals ingesting the cheese. The second outbreak affected 328 individuals, who presented ...
Tópico(s): Probiotics and Fermented Foods
2002 - Elsevier BV | Food Microbiology
Produção Nacional
Revisado por pares
Luíz Guilherme Dias Heneine, Valbert Nascimento Cardoso, JoséP. Daniel, Ibrahim F. Heneine,
L. G. D. Heneine, V. N. Cardoso, J. P. Daniel and I. F. Heneine. Detoxification of the T2 fraction from a scorpion (Tityus serrulatus, Lutz and Mello) venom by iodination and some immunogenic properties of the derivatives. Toxicon24, 501 – 505, 1986. — The iodination of the T2 fraction abolished its lethal capacity, and doses up to 30 times the ld50 were injected i.p. in mice without noticeable toxic effects. The modified fraction retained its immunological properties. Antibodies generated against the ...
Tópico(s): Nicotinic Acetylcholine Receptors Study
1986 - Elsevier BV | Toxicon
Produção Nacional
Revisado por pares
Guilherme Dias de Melo, Mary Marcondes, Rosemeri de Oliveira Vasconcelos, Gisele Fabrino Machado,
In dogs, there is an association of chronic visceral leishmaniasis with neurological symptoms, and very few publications have investigated whether these neurological manifestations correlate with specific alterations in brain. A total of 42 mixed-breed adult dogs were selected from the Veterinary Hospital of UNESP-Araçatuba and the Control Zoonosis Center in Araçatuba, São Paulo State, Brazil, which is an endemic area for visceral leishmaniasis. Animals presenting positive ELISA and/or positive ...
Tópico(s): Trypanosoma species research and implications
2009 - Elsevier BV | Veterinary Parasitology
Produção Nacional
Revisado por pares
Leandro Rodrigues de Lemos, Igor José Boggione Santos, Guilherme Dias Rodrigues, Gabriel Max Dias Ferreira, Luís Henrique Mendes da Silva, Maria do Carmo Hespanhol da Silva, Raquel Moreira Maduro de Carvalho,
The phase compositions in liquid−liquid equilibria of aqueous two-phase systems (ATPS) composed of the poly(ethylene oxide)− poly(propylene oxide)−poly(ethylene oxide) (PEO−PPO−PEO) triblock copolymer L35 and various salt solutions (sodium carbonate, sodium succinate, sodium acetate, ammonium citrate, and ammonium sulfate) at several temperatures, (283.15, 298.15, and 313.15) K, are presented. The influence of temperature in the binodal position was pronounced for almost all of the ATPS's, with the ...
Tópico(s): Process Optimization and Integration
2009 - American Chemical Society | Journal of Chemical & Engineering Data
Produção Nacional
Revisado por pares
Guilherme Dias Rodrigues, Leandro Rodrigues de Lemos, Luís Henrique Mendes da Silva, Maria do Carmo Hespanhol da Silva, Luís Antônio Minim, Jane Sélia dos Reis Coimbra,
A greener and more sensitive spectrophotometric procedure has been developed for the determination of phenol and o-cresol that exploits an aqueous two-phase system (ATPS) using a liquid-liquid extraction technique. An ATPS is formed mostly by water and does not require organic solvent. Other ATPS components used in this study were the polymer, polyethylene oxide, and some salts (i.e., Li(2)SO(4), Na(2)SO(4) or K(2)HPO(4)+KOH). The method is based on the reaction between phenol, sodium nitroprusside ( ...
Tópico(s): Analytical Chemistry and Sensors
2009 - Elsevier BV | Talanta
Produção Nacional
Revisado por pares
Guilherme Dias Rodrigues, Maria do Carmo Hespanhol da Silva, Luís Henrique Mendes da Silva, Leonel da Silva Teixeira, Vivianne Molica de Andrade,
Liquid−liquid equilibrium data of aqueous two-phase systems (ATPS) formed by mixture of aqueous solutions of triblock copolymer poly(ethylene oxide-b-propylene oxide-b-ethylene oxide), L64, and sulfate salts were obtained. L64 + lithium sulfate + water, L64 + magnesium sulfate + water, L64 + sodium sulfate + water, and L64 + zinc sulfate + water were formed at (278.15, 288.15, and 298.15) K. The influence of temperature in the binodal position was pronounced. The phase separation process was endothermic for the L64 + ...
Tópico(s): Extraction and Separation Processes
2009 - American Chemical Society | Journal of Chemical & Engineering Data
Produção Nacional
Revisado por pares
Guilherme Dias Rodrigues, Leonel da Silva Teixeira, Gabriel Max Dias Ferreira, Maria do Carmo Hespanhol da Silva, Luís Henrique Mendes da Silva, Raquel Moreira Maduro de Carvalho,
Phase diagrams of aqueous two-phase systems (ATPS) composed of F68 triblock copolymer + salt + water were constructed at different temperatures. The ATPS composed of F68 + (NH4)3C6H5O7 + H2O was investigated at (278.15, 288.15, and 298.15) K, and the F68 + Na3C6H5O7 + H2O, F68 + Na2C4H4O6 + H2O, F68 + Na2CO3 + H2O, and F68 + Na2C4H4O4 + H2O systems were examined at (283.15, 298.15, and 313.15) K. For all ATPS, the position of the binodal curve was affected by temperature, evidence of the enthalpic contribution to the formation ...
Tópico(s): Thermodynamic properties of mixtures
2009 - American Chemical Society | Journal of Chemical & Engineering Data
Produção Nacional
Revisado por pares
José Bento Alves, Cynthia Lopes Ferreira, Aline Fagundes Martins, Gerluza A.B. Silva, Guilherme Dias Alves, Tony P. Paulino, Pietro Ciancaglini, Geraldo Thedei, Marcelo Henrique Napimoga,
It has long been demonstrated that epidermal growth factor (EGF) has catabolic effects on bone. Thus, we examined the role of EGF in regulating mechanically induced bone modeling in a rat model of orthodontic tooth movement.The maxillary first molars of rats were moved mesially using an orthodontic appliance attached to the maxillary incisor teeth. Rats were randomly divided into 4 groups: (G1) administration of PBS (phosphate buffer saline) solution (n=24); (G2) administration of empty liposomes (n=24); ( ...
Tópico(s): Bone health and osteoporosis research
2009 - Elsevier BV | Life Sciences
Jón R. Blöndal, Chiara Goretti, Jens Kromann Kristensen,
... 2002 visit to OECD Headquarters in Paris, Mr. Guilherme DIAS, the Minister of Planning, Budget and Management, requested ...
Tópico(s): Fiscal Policy and Economic Growth
2003 - Organization for Economic Cooperation and Development | OECD Journal on Budgeting
Produção Nacional
Revisado por pares
Guilherme Dias Rodrigues, Maria do Carmo Hespanhol da Silva, Luís Henrique Mendes da Silva, Fernanda Jürgensen Paggioli, Luís Antônio Minim, Jane Sélia dos Reis Coimbra,
Tópico(s): Extraction and Separation Processes
2008 - Elsevier BV | Separation and Purification Technology
Produção Nacional
Revisado por pares
Karina Renata Gomes Cimini Saddi, Guilherme Dias Alves, Tony P. Paulino, Pietro Ciancaglini, José Bento Alves,
To evaluate the effects of local administration of epidermal growth factor (EGF) located within liposomes on recruitment of osteoclasts during mechanical force in rats.An orthodontic elastic band was inserted between the left upper first and second molars, to move mesially the first molar. Rats were randomly divided into 4 groups (n = 8): EGF (2 ng/microL) located within liposomes (group 1), liposomes only (group 2), soluble EGF (2 ng/microL; group 3), or vehicle alone (group 4). The solutions were injected ...
Tópico(s): Oral microbiology and periodontitis research
2008 - E.H Angle Education and Research Foundation | The Angle Orthodontist
Produção Nacional
Revisado por pares
Luís Henrique Mendes da Silva, Maria do Carmo Hespanhol da Silva, Rita de Cássia Superbi de Sousa, João Paulo Martins, Guilherme Dias Rodrigues, Jane Sélia dos Reis Coimbra, Luís Antônio Minim,
Surface excess enthalpy, ΔHσ, associated with the interfacial formation process was determined at 298.15 K for five different aqueous two-phase systems (ATPS): L35 + Li2SO4 + H2O, PEO1500 + Na2SO4 + H2O, PEO1500 + Li2SO4 + H2O, PEO1500 + citrate + H2O, and PEO4000 + Na2SO4 + H2O. Where L35 is one triblock copolymer denominated poly(oxide ethylene)-block-poly(oxide propylene)-block-poly(oxide ethylene) with molar mass 1900 mol·g−1 and 50 % EO, PEO1500 is poly(oxide ethylene) with molar mass 1500 mol·g−1 and PEO4000 is ...
Tópico(s): Extraction and Separation Processes
2008 - American Chemical Society | Journal of Chemical & Engineering Data
Produção Nacional
Revisado por pares
Guilherme Dias de Melo, Natalia Marangoni, Mary Marcondes, Valéria Marçal Felix de Lima, Gisele Fabrino Machado,
The hallmark microscopic lesion in canine visceral leishmaniosis is the accumulation of lymphocytes and macrophages parasitized by amastigotes of Leishmania in the lymphoid organs. Matrix metalloproteinase (MMP)-2 and MMP-9 are important for leukocyte migration as they degrade the type IV collagen in the basal lamina. Sera from 65 dogs, 53 with serological diagnosis of visceral leishmaniosis and 12 healthy ones, were analysed by gelatin-zymography to detect MMP-2 and MMP-9 activity. The infected ...
Tópico(s): Protease and Inhibitor Mechanisms
2010 - Elsevier BV | The Veterinary Journal
Produção Nacional
Revisado por pares
Gisele Fabrino Machado, Guilherme Dias de Melo, Olívia C. Moraes, Milena S. Souza, Mary Marcondes, Silvia Perri, Rosemeri de Oliveira Vasconcelos,
Canine visceral leishmaniasis is an important emerging disease with a multitude of clinical symptoms, including neurological alterations. Matrix metalloproteinases (MMP) are proteases implicated with the extracellular matrix remodelling and, within the central nervous system, these enzymes are involved with blood–brain-barrier disruption and inflammation. To establish the involvement of MMP-2 and -9 within the nervous tissue of dogs with spontaneous visceral leishmaniasis, fragments of nervous tissue ...
Tópico(s): Blood Coagulation and Thrombosis Mechanisms
2010 - Elsevier BV | Veterinary Immunology and Immunopathology
Produção Nacional
Revisado por pares
Valéria Spyridion Moustacas, Fabiane Gilli Zaffalon, M. A. Lagares, A.M. Loaiza-Eccheverri, F.C. Varago, Mariana Machado‐Neves, Luíz Guilherme Dias Heneine, Rubens Paes de Arruda, M. Henry,
The objective was to evaluate the suitability of using natural or lyophilized low density lipoproteins (LDL), in lieu of whole egg yolk, in extenders for cryopreserving ram semen. Once extragonadal sperm reserves were depleted in 10 fertile Santa Inês cross rams, two ejaculates per ram were collected for cryopreservation. Nine extenders were used: Tris-16% egg yolk extender with 5% glycerol as a control (T1), and substitution of whole egg yolk with 8, 12, 16 or 20% natural LDL (T2-T5, respectively), ...
Tópico(s): Male Reproductive Health Studies
2010 - Elsevier BV | Theriogenology
Produção Nacional
Revisado por pares
Guilherme Dias Rodrigues, Luís Henrique Mendes da Silva, Maria do Carmo Hespanhol da Silva,
The restricted availability of water sources suitable for consumption and high costs for obtaining potable water has caused an increase of the conscience concerning the use.Thus, there is a high demand for "environmentally safe methods" which are according to the principles of Green Chemistry.Moreover, these methods should be able to provide reliable results for the analysis of water quality for various pollutants, such as phenol.In this work, greener alternatives for sample preparation for phenol ...
Tópico(s): Analytical chemistry methods development
2010 - Brazilian Chemical Society | Química Nova
Produção Nacional
Revisado por pares
João Paulo Martins, Carolina de Paula Carvalho, Luís Henrique Mendes da Silva, Jane Sélia dos Reis Coimbra, Maria do Carmo Hespanhol da Silva, Guilherme Dias Rodrigues, Luís Antônio Minim,
Phase diagrams of aqueous two-phase systems composed of poly(ethylene) glycol (PEG) 1500, lithium sulfate, or magnesium sulfate were determined at (283.15, 298.15, and 313.15) K and of PEG 1500 + sodium sulfate were obtained at (278.15, 298.15, 305.65, and 313.15) K. The temperature effect on the position of the binodal curves was negligible, indicating a small enthalpic contribution to the phase separation process. The ability of the three salts to induce the formation of a biphasic system with PEG ...
Tópico(s): Crystallization and Solubility Studies
2007 - American Chemical Society | Journal of Chemical & Engineering Data
Produção Nacional
Revisado por pares
Maria Helena Santos, Patrícia Valério, A. M. Goes, M. Fátima Leite, Luíz Guilherme Dias Heneine, Herman S. Mansur,
In this work, novel composites based on calcium phosphates (CaP)/collagen (COL) doped with Zn+2 have been synthesized. They were characterized by SEM coupled to EDS microprobe in order to evaluate their morphology and chemical composition, respectively. The biocompatibility of these synthetic CaP/COL nanocomposites doped and undoped with Zn+2 was investigated through osteoblast cell culture assay. Calcium phosphates were produced via aqueous precipitation routes where two different phases were obtained, ...
Tópico(s): Collagen: Extraction and Characterization
2007 - IOP Publishing | Biomedical Materials
Produção Nacional
Maria Helena Santos, Luíz Guilherme Dias Heneine, Herman S. Mansur,
Composites were developed using calcium phosphate (CaP)/collagen (COL) doped with Zn+2 to attempt the materials association with adequate properties for biological applications in the recovery of the bone tissue by trauma or pathogenies. Hydroxyapatite (HAP) and hydroxyapatite-βtricalcium phosphate (HAPβTCP) were synthesized and doped with zinc nitrate. High purity grade type I collagen was extracted and purified from bovine pericardium. CaP doped and undoped with Zn+2 were produced with COL and the ...
Tópico(s): Titanium Alloys Microstructure and Properties
2007 - Elsevier BV | Materials Science and Engineering C
Produção Nacional
Revisado por pares
Vivianne Molica de Andrade, Guilherme Dias Rodrigues, Raquel Moreira Maduro de Carvalho, Luís Henrique Mendes da Silva, Maria do Carmo Hespanhol da Silva,
Phase diagrams of two-phase systems (ATPS) composed by the triblock copolymer L64 + organic salt (sodium tartrate, sodium succinate, sodium citrate, or ammonium citrate) + water, at different temperatures (278, 288, and 298 K) are presented in this work. Contrary to behavior of ATPS formed by inorganic salts, the study of the temperature influence in the liquid–liquid equilibrium behavior of L64–organic salts ATPS showed an exothermic character for phase separation process. Microcalorimetric measurements ...
Tópico(s): Crystallization and Solubility Studies
2011 - Elsevier BV | Chemical Engineering Journal
Produção Nacional
Revisado por pares
Natalia Marangoni, Guilherme Dias de Melo, Olívia C. Moraes, Milena S. Souza, S. H. V. Perri, Gisele Fabrino Machado,
Inflammation causes increases in the level of matrix metalloproteinases (MMPs), which, in central nervous system (CNS), are associated with neuroinflammation and disruption of blood-brain barrier. Analysis of cerebrospinal fluid (CSF) is pivotal for detecting diseases in CNS and, although a specific diagnosis may not be achieved, this analysis is helpful to confirm the diagnosis or to rule out relevant differential diagnoses. This study examined the levels of MMP-2 and MMP-9 in the CSF of dogs using ...
Tópico(s): Trypanosoma species research and implications
2011 - Wiley | Parasite Immunology
Produção Nacional
Revisado por pares
Leandro Rodrigues de Lemos, Pamela da Rocha Patrício, Guilherme Dias Rodrigues, Raquel Moreira Maduro de Carvalho, Maria do Carmo Hespanhol da Silva, Luís Henrique Mendes da Silva,
Tópico(s): Thermodynamic properties of mixtures
2011 - Elsevier BV | Fluid Phase Equilibria
Produção Nacional
Revisado por pares
Guilherme Dias de Melo, Gisele Fabrino Machado,
Tópico(s): Galectins and Cancer Biology
2011 - Springer Science+Business Media | Cell and Tissue Research
Produção Nacional
Revisado por pares
Beatriz M. Borelli, Inayara Cristina Alves Lacerda, Luciana R. Brandão, CM Vianna, M.C. Ferreira, Fátima C. O. Gomes, Luiz Simeão do Carmo, Luíz Guilherme Dias Heneine, C.A.R. Rosa,
The population dynamics of Staphylococcus spp. was studied during the ripening of Canastra Minas cheese at three farms located in the State of Minas Gerais, Brazil. The presence of coagulase (coa), thermonuclease (nuc), and enterotoxin (sea, seb, sec, and sed) genes was investigated in Staphylococcus strains isolated during the 60-day cheese-ripening period. The presence of the staphylococcal enterotoxins A, C, and D was also investigated in the cheese samples. Cheese samples that were matured for ...
Tópico(s): Milk Quality and Mastitis in Dairy Cows
2011 - UNIVERSIDADE FEDERAL DE MINAS GERAIS | Arquivo Brasileiro de Medicina Veterinária e Zootecnia