
Sheila Cristina Ouriques Martins, F. Mont’alverne, Letícia Costa Rebello, Daniel Giansante Abud, Gisele Sampaio Silva, Fabrício Oliveira Lima, Bruno S.M. Parente, Guilherme Seizem Nakiri, Mário B. Faria, Michel Eli Frudit, João José Freitas de Carvalho, Eduardo Waihrich, José Antônio Fiorot Júnior, Fabrício Bruno Cardoso, Raquel C.T. Hidalgo, Viviane Flumignan Zétola, Fernanda Carvalho, Ana Cláudia de Souza, Francisco Antunes Dias, Diego Bandeira, Maramélia Miranda, Mário Bernardes Wagner, Leonardo Augusto Carbonera, Jamary Oliveira‐Filho, Daniel C. Bezerra, David S. Liebeskind, Joseph P. Broderick, Carlos A. Molina, José E. Fogolin Passos, Jeffrey L. Saver, Octávio Marques Pontes‐Neto, Raul G. Nogueira,
Randomized trials involving patients with stroke have established that outcomes are improved with the use of thrombectomy for large-vessel occlusion. These trials were performed in high-resource countries and have had limited effects on medical practice in low- and middle-income countries.
Tópico(s): Cerebrovascular and Carotid Artery Diseases
2020 - Massachusetts Medical Society | New England Journal of Medicine

Aline Lopes Chagas, Ângelo Alves de Mattos, Flair José Carrilho, Paulo Lisboa Bittencourt, Denise Cerqueira Paranaguá‐Vezozzo, Natally Horvat, Manoel de Souza Rocha, Venâncio Avancini Ferreira Alves, Gabriela Perdomo Coral, Mário Reis Álvares‐da‐Silva, Fábio Marinho do Rego Barros, Marcos Roberto de Menezes, Lucas Moretti Monsignore, Fabrício Ferreira Coelho, Renato Ferreira da Silva, Rita de Cássia Martins Alves da Silva, I.F.S.F. Boin, Luiz Augusto Carneiro D’Albuquerque, José Huygens Parente Garcia, Guilherme Eduardo Gonçalves Felga, Airton Mota Moreira, Maria Ignez Braghiroli, Paulo M. Hoff, Vivianne Mello, Mariana Fonseca Dottori, Tiago Pugliese Branco, Leonardo de Lucca Schiavon, Thaisa de Fatima Almeida Costa,
Hepatocellular carcinoma (HCC) is one of the leading causes of cancer-related mortality worldwide. The Brazilian Society of Hepatology (SBH) published in 2015 its first recommendations about the management of HCC. Since then, new data have emerged in the literature, prompting the governing board of SBH to sponsor a single-topic meeting in August 2018 in São Paulo. All the invited experts were asked to make a systematic review of the literature reviewing the management of HCC in subjects with cirrhosis. ...
Tópico(s): Liver Disease and Transplantation
2020 - Instituto Brasileiro de Estudos e Pesquisas de Gastroenterologia (IBEPEGE) | Arquivos de Gastroenterologia

Paula Soares de Mattos Carneiro Valente, Carolina Lyra Barreira Carneiro, Ridson Guilherme Parente de Aguiar, Francisco Emanoel Albuquerque de Souza Júnior, Alex Andrade Maciel, Edgar Marçal, José Barbosa, João Crispim Moraes Lima Ribeiro,
Glaucoma is a progressive optic neuropathy that requires continuous monitoring. The purpose of the study was to develop and evaluate the usability of a mobile application, for iOS and Android platforms, containing functionalities to improve patients' knowledge about glaucoma and facilitate their treatment. The application was developed by a multidisciplinary team using an adapted version of a co-design methodology. Volunteers were selected, among patients and patients' relatives, from the Instituto ...
Tópico(s): Ophthalmology and Visual Impairment Studies
2021 - Springer Science+Business Media | International Ophthalmology

Ricardo Schechtman, Valéria Salomão Garcia, Sérgio Mikio Koyama, Guilherme Cronemberg Parente,
The new Basel II Capital Accord has demanded a lot of attention from regulatory and regulated entities due to its innovations in determining capital requirements, particularly in the area of credit risk. This paper simulates the application of Basel II IRB foundation approach for the computation of capital and provision requirements relative to the credit risk of major Brazilian banks' corporate credit portfolios. The IRB necessary parameters of probabilities of default are estimated using variables ...
Tópico(s): Financial Distress and Bankruptcy Prediction
2004 - RELX Group (Netherlands) | SSRN Electronic Journal
Pedro Pereira, Miguel Mascarenhas, Tiago Ribeiro, João Afonso, João Ferreira, Filipe Vilas‐Boas, Marco Parente, Renato Natal Jorge, Guilherme Macedo,
Background and study aims Indeterminate biliary strictures pose a significative clinical challenge. Dilated, irregular, and tortuous vessels, often described as tumor vessels, are frequently reported in biliary strictures with high malignancy potential during digital single-operator cholangioscopy (D-SOC). In recent years, the development of artificial intelligence (AI) algorithms for application to endoscopic practice has been intensely studied. We aimed to develop an AI algorithm for automatic detection ...
Tópico(s): Esophageal and GI Pathology
2022 - Thieme Medical Publishers (Germany) | Endoscopy International Open
João Afonso, Miguel Mascarenhas, João Ferreira, Hélder Cardoso, Tiago Ribeiro, Patrícia Andrade, Marco Parente, Renato Natal Jorge, Guilherme Macedo,
Tópico(s): Gastric Cancer Management and Outcomes
2022 - Springer Science+Business Media | Medical & Biological Engineering & Computing
Miguel Mascarenhas, João Ferreira, Helena Cardoso, João Afonso, Tiago Ribeiro, Patrícia Andrade, Marco Parente, Renato Natal Jorge, Guilherme Macedo,
Tópico(s): AI in cancer detection
2021 - Springer Science+Business Media | Techniques in Coloproctology
Miguel Mascarenhas, João Ferreira, Hélder Cardoso, João Afonso, Tiago Ribeiro, Patrícia Andrade, Marco Parente, Renato Natal Jorge, Guilherme Macedo,
Abstract Colon capsule endoscopy (CCE) is a minimally invasive alternative to conventional colonoscopy. Most studies on CCE focus on colorectal neoplasia detection. The development of automated tools may address some of the limitations of this diagnostic tool and widen its indications for different clinical settings. We developed an artificial intelligence model based on a convolutional neural network (CNN) for the automatic detection of blood content in CCE images. Training and validation datasets ...
Tópico(s): Gastrointestinal Bleeding Diagnosis and Treatment
2021 - Thieme Medical Publishers (Germany) | Endoscopy International Open
Miguel Mascarenhas, Tiago Ribeiro, João Afonso, João Ferreira, Hélder Cardoso, Patrícia Andrade, Marco Parente, Renato Natal Jorge, Guilherme Macedo,
Capsule endoscopy has revolutionized the management of patients with obscure gastrointestinal bleeding. Nevertheless, reading capsule endoscopy images is time-consuming and prone to overlooking significant lesions, thus limiting its diagnostic yield. We aimed to create a deep learning algorithm for automatic detection of blood and hematic residues in the enteric lumen in capsule endoscopy exams.A convolutional neural network was developed based on a total pool of 22,095 capsule endoscopy images ( ...
Tópico(s): Gastric Cancer Management and Outcomes
2021 - Karger Publishers | GE Portuguese Journal of Gastroenterology

Eduardo Varela Parente, Guilherme Lacerda, Marcelo Galindo Silvares,
Class III malocclusion is one of the most common deformities that requires correction through orthodontic-surgical treatment. These patients present different facial patterns depending on the occlusal plane angulation. These patients may benefit from surgical manipulation of the occlusal plane, because only bite correction does not always lead to the improvement of the facial deformity. The purpose of this paper is to show the surgical manipulation of the occlusal plane in Class III patients based ...
Tópico(s): Facial Rejuvenation and Surgery Techniques
2014 - Scientific Research Publishing | Open Journal of Stomatology

Karine Martins de Oliveira, Benedito Rodrigues da Silva Neto, Juliana Alves Parente, Roosevelt Alves da Silva, Guilherme Oliveira Quintino, Aline Raquel Voltan, Maria José Soares Mendes‐Giannini, Célia Maria de Almeida Soares, Maristela Pereira,
Abstract Background The fungus Paracoccidioides spp is the agent of paracoccidioidomycosis (PCM), a pulmonary mycosis acquired by the inhalation of fungal propagules. Paracoccidioides malate synthase ( Pb MLS) is important in the infectious process of Paracoccidioides spp because the transcript is up-regulated during the transition from mycelium to yeast and in yeast cells during phagocytosis by murine macrophages. In addition, Pb MLS acts as an adhesin in Paracoccidioides spp . The evidence for the ...
Tópico(s): Fungal Infections and Studies
2013 - BioMed Central | BMC Microbiology

Casandra Genoveva Rosales Martins Ponce de Leon, Leandro Yukio Mano, Danielle da Silva Fernandes, Rayanne Augusta Parente Paula, Guilherme da Costa Brasil, Laiane Medeiros Ribeiro,
ABSTRACT Objective: to assess nursing students’ emotions undergoing maternal-child clinical simulation. Methods: an observational study, carried out between June and July 2019. The Focus Group technique was used, with 28 nursing students, randomly distributed into three groups, with qualitative (Bardin technique) and quantitative data (Artificial Intelligence) analysis, to analyze emotions through facial expressions, tone of voice and description of speeches. Results: we defined two categories: “It ...
Tópico(s): Nursing Diagnosis and Documentation
2023 - Associação Brasileira de Enfermagem | Revista Brasileira de Enfermagem
Miguel Mascarenhas, Tiago Ribeiro, João Afonso, João Ferreira, Hélder Cardoso, Patrícia Andrade, Marco Parente, Renato Natal Jorge, Miguel Mascarenhas, Guilherme Macedo,
Background and study aims Colon capsule endoscopy (CCE) is a minimally invasive alternative to conventional colonoscopy. However, CCE produces long videos, making its analysis time-consuming and prone to errors. Convolutional neural networks (CNN) are artificial intelligence (AI) algorithms with high performance levels in image analysis. We aimed to develop a deep learning model for automatic identification and differentiation of significant colonic mucosal lesions and blood in CCE images. Patients ...
Tópico(s): Gastric Cancer Management and Outcomes
2022 - Thieme Medical Publishers (Germany) | Endoscopy International Open
João Ferreira, Miguel José da Quinta e Costa de Mascarenhas Saraiva, João Afonso, Tiago Ribeiro, Hélder Cardoso, Ana Patrícia Andrade, Miguel Nuno Gameiro de Mascarenhas Saraiva, Marco Parente, Renato Natal Jorge, Susana Lopes, Guilherme Manuel Gonçalves de Macedo,
Capsule endoscopy is a central element in the management of patients with suspected or known Crohn's disease. In 2017, PillCam™ Crohn's Capsule was introduced and demonstrated to have greater accuracy in the evaluation of extension of disease in these patients. Artificial intelligence [AI] is expected to enhance the diagnostic accuracy of capsule endoscopy. This study aimed to develop an AI algorithm for the automatic detection of ulcers and erosions of the small intestine and colon in PillCam™ Crohn' ...
Tópico(s): Colorectal Cancer Screening and Detection
2021 - Oxford University Press | Journal of Crohn s and Colitis
Miguel Mascarenhas, Tiago Ribeiro, João Ferreira, Filipe Vilas‐Boas, João Afonso, Ana Luísa Santos, Marco Parente, Renato Natal Jorge, Pedro Pereira, Guilherme Macedo,
The diagnosis and characterization of biliary strictures (BSs) is challenging. The introduction of digital single-operator cholangioscopy (DSOC) that allows direct visual inspection of the lesion and targeted biopsy sampling significantly improved the diagnostic yield in patients with indeterminate BSs. However, the diagnostic efficiency of DSOC remains suboptimal. Convolutional neural networks (CNNs) have shown great potential for the interpretation of medical images. We aimed to develop a CNN-based ...
Tópico(s): Pancreatic and Hepatic Oncology Research
2021 - Elsevier BV | Gastrointestinal Endoscopy
Miguel Mascarenhas, João Afonso, Tiago Ribeiro, João Ferreira, Hélder Cardoso, Ana Patrícia Andrade, Marco Parente, Renato Natal Jorge, Miguel Mascarenhas, Guilherme Macedo,
Objective Capsule endoscopy (CE) is pivotal for evaluation of small bowel disease. Obscure gastrointestinal bleeding most often originates from the small bowel. CE frequently identifies a wide range of lesions with different bleeding potentials in these patients. However, reading CE examinations is a time-consuming task. Convolutional neural networks (CNNs) are highly efficient artificial intelligence tools for image analysis. This study aims to develop a CNN-based model for identification and differentiation ...
Tópico(s): Gastric Cancer Management and Outcomes
2021 - BMJ | BMJ Open Gastroenterology

Raphael Câmara Medeiros Parente, Eduardo Faerstein, Roger Keller Celeste, Guilherme Loureiro Werneck,
Increasing life expectancy has made it ever more important to study the factors that influence the age at the menopause, given that when it is reached outside of the normal range, it is associated with increased risk of osteoporosis and cardiovascular diseases, among other conditions. Among the factors studied in relation to early menopause, smoking is prominent. Destruction of the ovarian follicles is one of the mechanisms postulated for this effect. The aim of this study was to review and describe ...
Tópico(s): Cancer Risks and Factors
2008 - Elsevier BV | Maturitas

Sérgio Luiz Arruda Parente Filho, Pedro Eduardo Andrade de Carvalho Gomes, Guilherme Aguiar Forte, Laio Ladislau Lopes Lima, Geraldo Bezerra da Silva, Gdayllon Cavalcante Meneses, Alice Maria Costa Martins, Elizabeth De Francesco Daher,
The excessive chase for beauty standards and the rise of muscle dysmorphia have ultimately led to an increase in androgenic–anabolic steroids (AAS) and intramuscular injections of vitamins A, D and E (ADE) abuse, which is associated with several adverse effects and has become a public health issue. This review of literature discusses kidney injury associated with the use of AAS and ADE, highlighting the mechanisms of acute and chronic renal lesion, such as direct renal toxicity, glomerular hyperfiltration ...
Tópico(s): Muscle and Compartmental Disorders
2019 - Elsevier BV | Nefrología

Walter B. Mors, Maria Célia do Nascimento, José Paz Parente, Maria Helena da Silva, Paulo A. Melo, Guilherme Suarez‐Kurtz,
Ethanolic extracts of the aerial parts of Eclipta prostrata L. (Asteraceae) neutralized the lethal activity of the venom of South American rattlesnake (Crotalus durissus terrificus) when mixed in vitro before i.p. injection into adult Swiss mice. Samples of ethanolic extract corresponding to 1.8 mg of dry extract per animal neutralized up to four lethal doses of the venom (LD50 = 0.08 micrograms venom/g animal). Three substances isolated from the plant--wedelolactone (0.54 mg/animal), sitosterol (2.3 mg/ ...
Tópico(s): Healthcare and Venom Research
1989 - Elsevier BV | Toxicon
Tiago Ribeiro, Miguel Mascarenhas, João Afonso, João Ferreira, Filipe Vilas‐Boas, Marco Parente, Renato Natal Jorge, Pedro Pereira, Guilherme Macedo,
Characterization of biliary strictures is challenging. Papillary projections (PP) are often reported in biliary strictures with high malignancy potential during digital single-operator cholangioscopy. In recent years, the development of artificial intelligence (AI) algorithms for application to endoscopic practice has been intensely studied. We aimed to develop an AI algorithm for automatic detection of PP in digital single-operator cholangioscopy images.A convolutional neural network (CNN) was developed. ...
Tópico(s): Pancreatic and Hepatic Oncology Research
2021 - Lippincott Williams & Wilkins | Clinical and Translational Gastroenterology
Miguel Mascarenhas, João Afonso, Tiago Ribeiro, João Ferreira, Hélder Cardoso, Patrícia Andrade, Raquel Gonçalves, Pedro Cardoso, Marco Parente, Renato Natal Jorge, Guilherme Macedo,
capsule endoscopy (CE) revolutionized the study of the small intestine. Nevertheless, reviewing CE images is time-consuming and prone to error. Artificial intelligence algorithms, particularly convolutional neural networks (CNN), are expected to overcome these drawbacks. Protruding lesions of the small intestine exhibit enormous morphological diversity in CE images. This study aimed to develop a CNN-based algorithm for the automatic detection small bowel protruding lesions.a CNN was developed using ...
Tópico(s): Gastric Cancer Management and Outcomes
2021 - Arán Ediciones | Revista Española de Enfermedades Digestivas

Ezequiel Aguiar Parente, Guilherme Emílio Ferreira, Beatriz de Cavalcante Almeida, José Isnack Ponte de Alencar Filho, Jéssica nascimento de Souza, José Wellington Oliveira Lima, Gilson Holanda Almeida,
Introduction: The use of psychoactive drugs in the world population increased until 2011 as well the alcohol consumption of university students. Many studies have appointed factors that may aggravate the problem. Objective: To evaluate the alcohol use by medical students in a private medical institution in Fortaleza, Ceará. Methods: A quantitative, cross-sectional study developed from July of 2015 to May 2016. Two instruments for collecting data were used: one related to socioeconomic, demographic, ...
Tópico(s): Health, Nursing, Elderly Care
2017 - CENTRO UNIVERSITÁRIO CHRISTUS | Journal of Health & Biological Sciences

Edmar Maciel Lima, Tereza de Jesus Pinheiro Gomes Bandeira, Marcelo José Borges de Miranda, Guilherme Emílio Ferreira, Ezequiel Aguiar Parente, Nelson Sarto Piccolo, Manoel Odorico De Moraes Flho,
Introduction: Fish are usually exposed to higher microbial loads than land or air animals. The microbiota of fish mostly consists of Pseudomonas spp., Aeromonas spp., Shewanella putrefasciens, Acinetobacter spp. and Moraxella spp. The objective of this study was to analyze the oral cavity, and skin tissue microbiota on the Nile tilapia (Oreochromis niloticus), a fish species raised commercially in Brazil. Methods: Samples were collected from the oral cavity and skin of 20 Nile tilapia specimens (Oreochromis ...
Tópico(s): Microbial Metabolism and Applications
2016 - CENTRO UNIVERSITÁRIO CHRISTUS | Journal of Health & Biological Sciences

Felipe Simões Canavez, Guilherme Loureiro Werneck, Raphael Câmara Medeiros Parente, Roger Keller Celeste, Eduardo Faerstein,
Tópico(s): Menopause: Health Impacts and Treatments
2009 - Springer Science+Business Media | Archives of Gynecology and Obstetrics

Frederico Guilherme Graeff, Alexandre Castelo Branco Vaz Parente, Cristina Marta Del‐Ben, Francisco Silveira Guimarães,
This review covers the effect of drugs affecting anxiety using four psychological procedures for inducing experimental anxiety applied to healthy volunteers and patients with anxiety disorders. The first is aversive conditioning of the skin conductance responses to tones. The second is simulated public speaking, which consists of speaking in front of a video camera, with anxiety being measured with psychometric scales. The third is the Stroop Color-Word test, in which words naming colors are painted ...
Tópico(s): Mental Health Research Topics
2003 - Associação Brasileira de Divulgação Científica | Brazilian Journal of Medical and Biological Research

Alexandre Castelo Branco Vaz Parente, Cybele Garcia-Leal, Cristina Marta Del‐Ben, Francisco Silveira Guimarães, Frederico Guilherme Graeff,
Drug-free symptomatic panic patients, drug-treated nonsymptomatic patients and healthy controls were submitted to simulated public speaking. Subjective anxiety, cognitive impairment and discomfort measured by the visual analog mood scale as well as skin conductance level were higher in symptomatic patients than in controls at the beginning of the experimental session, nonsymptomatic patients lying in between. Subjective sedation, spontaneous fluctuations of skin conductance, heart rate and blood ...
Tópico(s): Neural and Behavioral Psychology Studies
2005 - Elsevier BV | European Neuropsychopharmacology

Carla Peluso, Fernando Luiz Affonso Fonseca, Itatiana Ferreira Rodart, Viviane Cavalcanti, Guilherme Gastaldo, Denise Maria Christofolini, Caio Parente Barbosa, Bianca Bianco,
Ovarian reserve tests provide knowledge of a possible response to controlled ovarian hyperstimulation in patients undergoing assisted reproduction treatment, allowing management and alteration of treatment protocol with the appropriate dose of gonadotrophin. Several parameters have been used as predictors of ovarian response. The basal FSH serum level on the third day of the menstrual cycle seemed to be the best predictor, but with significant intraindividual variability from one cycle to another. ...
Tópico(s): Assisted Reproductive Technology and Twin Pregnancy
2014 - Elsevier BV | Clinica Chimica Acta

Antonio Luis Eiras-Araújo, Daniella Braz Parente, Alexandre Cerqueira da Silva, Guilherme Rezende, Gustavo Braga Mendes, Ronir Raggio Luiz, Rebecca de Oliveira Souza, Stéfanos Generalis, Rosana Souza Rodrigues, Renata Mello Perez,
Tópico(s): Hepatocellular Carcinoma Treatment and Prognosis
2023 - Springer Science+Business Media | European Radiology

Felipe Padovani Trivelato, Daniel Giansante Abud, Alexandre Cordeiro Ulhôa, Eduardo Waihrich, Thiago Giansante Abud, Luis Henrique Castro Afonso, Guilherme Seizem Nakiri, Guilherme Duarte de Castro, Bruno de Sousa Mendes Parente, Rodrigo dos Santos Silva, Luciano Bambini Manzato, Lucas Eduardo Bonadio, Dinark Conceição Viana, José Ricardo Vanzin, Carlos Eduardo Baccin, Marco Túlio Salles Rezende,
Background and Purpose— Flow diverter technology improvements are necessary to provide safe and good results and enable the treatment of a larger variety of aneurysms. We report a nationwide experience with the Derivo Embolization Device in the treatment of intracranial aneurysms. Methods— BRAIDED (Brazilian Registry of Aneurysms Assigned to Intervention With the Derivo Embolization Device) is a multicenter, prospective, interventional, single-arm trial of the Derivo Embolization Device for the treatment ...
Tópico(s): Cerebrovascular and Carotid Artery Diseases
2019 - Lippincott Williams & Wilkins | Stroke

David Nunes de Lima, Ridson Guilherme Parente de Aguiar, Bruna Sobreira Kubrusly, Danielle S. Macêdo, Marcos Kubrusly, Danilo Lopes Ferreira Lima, Lia Lira Olivier Sanders,
Spirituality and altruism may be critical coping strategies to minimize emotional pain during period of crisis. Here we aim to investigate how spirituality and altruism are related and whether they influence medical students' levels of stress during the COVID-19 pandemic. Data were collected when most Brazilian states had already been promoting social isolation in response to the COVID-19 pandemic using self-reported measures: the Perceived Stress Scale 4, the Self-Spirituality Rating Scale, and ...
Tópico(s): Death Anxiety and Social Exclusion
2022 - Grupo de Pesquisa Metodologias em Ensino e Aprendizagem em Ciências | Research Society and Development