Jeffrey D. Sachs, Salim S. Abdool Karim, Lara B. Aknin, Joseph R. Allen, Kirsten Brosbøl, Gabriela Cuevas Barron, Peter Daszak, María Fernanda Espinosa, Vítor Gaspar, Alejandro Gaviría, Andy Haines, Peter J. Hotez, Phoebe Koundouri, Felipe Larraín Bascuñán, Jong‐Koo Lee, Muhammad Ali Pate, Paul Polman, Srinath Reddy, Ismaïl Serageldin, Raj Shah, John Thwaites, Vaira Vīķe-Freiberga, Chen Wang, Miriam Were, Lan Xue, Min Zhu, Chandrika Bahadur, María Elena Bottazzi, Yanis Ben Amor, Lauren Barredo, Özge Karadağ Çaman, Guillaume Lafortune, Emma Torres, Ismini Ethridge, Juliana G E Bartels,
The Lancet COVID-19 Commission was launched on July 9, 2020, to assist governments, civil society, and UN institutions in responding effectively to the COVID-19 pandemic. The Commission aims to offer practical solutions to the four main global challenges posed by the pandemic: suppressing the pandemic by means of pharmaceutical and non-pharmaceutical interventions; overcoming humanitarian emergencies, including poverty, hunger, and mental distress, caused by the pandemic; restructuring public and ...
Tópico(s): COVID-19 Clinical Research Studies
2020 - Elsevier BV | The Lancet
Jeffrey D. Sachs, Salim S. Abdool Karim, Lara B. Aknin, Joseph R. Allen, Kirsten Brosbøl, Gabriela Cuevas Barron, Peter Daszak, María Fernanda Espinosa, Vítor Gaspar, Alejandro Gaviría, Andy Haines, Peter J. Hotez, Phoebe Koundouri, Felipe Larraín B., Jong‐Koo Lee, Muhammad Ali Pate, Paul Polman, Gabriela Ramos, K. Srinath Reddy, Ismaïl Serageldin, Rajiv Shah, John Thwaites, Vaira Vīķe-Freiberga, Chen Wang, Miriam Were, Lan Xue, Min Zhu, María Elena Bottazzi, Francesca Colombo, George Laryea-Adjei, Yanis Ben Amor, Özge Karadağ Çaman, Guillaume Lafortune, Emma Torres, Ismini Ethridge, Juliana G E Bartels,
The Lancet COVID-19 Commission calls for three urgent actions in the COVID-19 response (our broader overview is available on our website). First, all regions with high rates of new COVID-19 cases, including the USA and the European Union (EU), should intensify measures to minimise community transmission alongside rapid deployment of COVID-19 vaccines. Second, governments should urgently and fully fund WHO and the Access to COVID-19 Tools (ACT) Accelerator,1 including COVAX. Third, the G20 countries ...
Tópico(s): Viral Infections and Outbreaks Research
2021 - Elsevier BV | The Lancet
Jeffrey D. Sachs, Salim S. Abdool Karim, Lara B. Aknin, Joseph R. Allen, Kirsten Brosbøl, Francesca Colombo, Gabriela Cuevas Barron, María Fernanda Espinosa, Vítor Gaspar, Alejandro Gaviría, Andy Haines, Peter J. Hotez, Phoebe Koundouri, Felipe Larraín Bascuñán, Jong‐Koo Lee, Muhammad Ali Pate, Gabriela Ramos, K. Srinath Reddy, Ismaïl Serageldin, John Thwaites, Vaira Vīķe-Freiberga, Chen Wang, Miriam Were, Lan Xue, Chandrika Bahadur, María Elena Bottazzi, Chris Bullen, George Laryea-Adjei, Yanis Ben Amor, Özge Karadağ Çaman, Guillaume Lafortune, Emma Torres, Lauren Barredo, Juliana G E Bartels, Neena Joshi, Margaret Hellard, Uyen Kim Huynh, Shweta Khandelwal, Jeffrey V. Lazarus, Susan Michie,
As of May 31, 2022, there were 6·9 million reported deaths and 17·2 million estimated deaths from COVID-19, as reported by the Institute for Health Metrics and Evaluation (IHME; throughout the report, we rely on IHME estimates of infections and deaths; note that the IHME gives an estimated range, and we refer to the mean estimate). This staggering death toll is both a profound tragedy and a massive global failure at multiple levels. Too many governments have failed to adhere to basic norms of institutional ...
Tópico(s): Climate Change and Health Impacts
2022 - Elsevier BV | The Lancet
Pascale Jeannin, Barbara Bottazzi, Marina Sironi, Andrea Doni, Marco Rusnati, Marco Presta, Virginia Maina, Giovanni Magistrelli, Jean François Haeuw, Guillaume Hoeffel, Nathalie Thiéblemont, Nathalie Corvaı̈a, Cecília Garlanda, Yves Delneste, Alberto Mantovani,
Outer membrane protein A (OmpA) is a conserved major component of the outer membrane of Enterobacteriaceae. Here, we report that OmpA from Klebsiella pneumoniae (KpOmpA) activates macrophages and dendritic cells (DCs) in a TLR2-dependent way. However, TLR2 does not account for binding of KpOmpA to innate immune cells. KpOmpA binds the scavenger receptors (SRs) LOX-1 and SREC-I, but not other members of the same family. LOX-1 colocalizes and cooperates with TLR2 in triggering cellular responses. The ...
Tópico(s): Inflammasome and immune disorders
2005 - Cell Press | Immunity
Jakub Fronczek, Kamil Polok, Dylan W. de Lange, Christian Jung, Michael Beil, Andrew Rhodes, Jesper Fjølner, Jacek Górka, Finn H. Andersen, Antonio Artigas, Maurizio Cecconi, Steffen Christensen, Michael Joannidis, Susannah Leaver, Brian Marsh, Alessandro Morandi, Rui P. Moreno, Sandra Oeyen, Christina Agvald‐Öhman, Bernardo Bollen Pinto, Joerg C. Schefold, Andreas Valentin, Sten Walther, Ximena Watson, Tilemachos Zafeiridis, Sigal Sviri, Peter Vernon van Heerden, Hans Flaatten, Bertrand Guidet, Wojciech Szczeklik, René Schmutz, Fabian Wimmer, Philipp Eller, Michael Joannidis, Pieter De Buysscher, Nikolaas De Neve, Sandra Oeyen, Walter Swinnen, Bernardo Bollen Pinto, Paul Abraham, Leila Hergafi, Joerg C. Schefold, Ewelina Biskup, Pinilla Roman Hervey Piza, I. Taliadoros, Jesper Fjølner, Nilanjan Dey, Christoffer Sølling, Bodil Steen Rasmussen, Steffen Christensen, Xavier Forceville, Guillaume Besch, Hervé Mentec, P. Michel, Philippe Mateu, P. Michel, Lucie Vettoretti, Jérémy Bourenne, Nathalie Marin, Max Guillot, Nadia Aïssaoui, Cyril Goulenok, Nathalie Thieulot-Rolin, Jonathan Messika, Lionel Lamhaut, Bertrand Guidet, Cyril Charron, Alexander Lauten, Anne Lena Sacher, Thorsten Brenner, Marcus Franz, Frank Bloos, Henning Ebelt, Stefan J. Schaller, Kristina Fuest, Christian Rabe, Thorben Dieck, Stephan Steiner, Tobias Graf, Amir M. Nia, Chul Won Jung, Rolf Alexander Jánosi, Patrick Meybohm, Philipp Simon, Stefan Utzolino, Tim Rahmel, Eberhard Barth, Chul Won Jung, Michael Schuster, Zoi Aidoni, Stavros Aloizos, P. Tasioudis, Klairi Lampiri, V. Zisopoulou, Ifigenia Ravani, E. Pagaki, Anna Antoniou, Θεόδωρος Κατσούλας, A. Kounougeri, Giorgos Marinakis, Fotios Tsimpoukas, Αikaterini Spyropoulou, Paris Zygoulis, Aikaterini Kyparissi, Mrigank S. Gupta, Mohan Gurjar, imatinibem mají, Ian Hayes, Brian Marsh, Yvelynne P. Kelly, Andrew Westbrook, G Fitzpatrick, M. Maheshwari, Catherine Motherway, Giampiero Negri, Savino Spadaro, Giuseppe Nattino, M. Pedeferri, Annalisa Boscolo, Silvia Rossi, Giuseppe Calicchio, L. Cubattoli, Gabriella Di Lascio, Mario Barbagallo, F. Berruto, Daniela Codazzi, Andrea Bottazzi, P Fumagalli, G. Negro, Gabriele Lupi, Francesco Savelli, G. A. Vulcano, Roberto Fumagalli, Andrea Marudi, Ugo Lefons, Rosalba Lembo, M. Babini, A. Paggioro, Vieri Parrini, M. Zaccaria, Stefano Clementi, C. Gigliuto, Francesca Facondini, S Pastorini, Sara Munaron, Italo Calamai, A. Bocchi, Andrea Adorni, Maria Grazia Bocci, Andrea Cortegiani, Tiziana Casalicchio, S. Mellea, Emauele Graziani, Massimo Barattini, Elisabetta Brizio, Marianna Rossi, Michael Hahn, Hans Flaatten, N. Kemmerer, Hans Frank Strietzel, Knut Dybwik, T. Legernaes, Pål Klepstad, Elinor Jeanette Olaussen, Keith M. Olsen, O. M. Brresen, G. Bjorsvik, Fahimeh Andersen, S. Maini, Lutz Fehrle, Mirosław Czuczwar, Paweł Krawczyk, Mirosław Ziętkiewicz, Łukasz R. Nowak, Katarzyna Kotfis, Katarzyna Cwyl, Ryszard Gajdosz, Jowita Biernawska, Romuald Bohatyrewicz, Ryszard Gawda, Paweł Grudzień, Paweł Nasiłowski, Natalia Popek, Waldemar Cyrankiewicz, Katarzyna Wawrzyniak, Marek Wnuk, Dariusz Maciejewski, Dorota Studzińska, Maciej Żukowski, Szymon Bernas, Mariusz Piechota, Wojciech Szczeklik, Ilona Nowak, Jakub Fronczek, Marta Serwa, Waldemar Machała, Jan Stefaniak, Maria Wujtewicz, Paul K. Maciejewski, Małgorzata Szymkowiak, Barbara Adamik, Kamil Polok, Jacek Górka, Nuno Catorze, Miguel Castelo-Branco, Nélson Barros, Iliene Carolina Barros, Andriy Krystopchuk, Teresa Honrado, Cardoso de Sousa, F. García Muñoz, M. Rebêlo, R. Gomes, José Pedro L. Nunes, Celeste Dias, Ângela Fernandes, Cristina Petrişor, Bendelic Constantin, Vladislav Belskiy, B. Boskholov, E. Rodríguez, Gerardo Aguilar, G. Masdeu, Marián Irazábal Jaimes, Adriana Mira, María Bodí, Jason A. Mendoza, Sonia López‐Cuenca, Mauricio Guzmán, Jesús Rico‐Feijoo, Mercedes Ibarz, Josep Trenado, Rafael Kawati, Joakim Sivik, Jessica Nauska, Daniel Smole, Fredric Parenmark, J. Lyrén, Klaus Juergen Rockstroh, Sara Rydén, Martin Spångfors, Morten Strinnholm, Sten Walther, Lina De Geer, P.-J. Nordlund, S. Pålsson, Harald Zetterquist, Annette Nilsson, Klara Thiringer, Mårten Jungner, Björn P. Bark, B. Nordling, Helena Sköld, Caroline Brorsson, Sofia Persson, Annika Bergström, Johan Berkius, Jessica Holmström, I. van Dijk, L. E. M. van Lelyveld-Haas, Tim C. Jansen, Fleur G. C. A. Nooteboom, Peter H. J. van der Voort, Dylan W. de Lange, Willem Dieperink, M. C. de Waard, Annemieke Smet, Laura Bormans, Tom Dormans, Ged Dempsey, Sunny Mathew, Ashok Raj, Irina Grecu, Jason Cupitt, Tom Lawton, Ross A. Clark, Mihai Popescu, Nick Spittle, Maria Faulkner, Amanda Cowton, Patricia Williams, E. Elloway, Michael Reay, Srikanth Chukkambotla, R. Kumar, Nawaf Al-Subaie, L. Kent, Tamm Ti, Istvan Kajtor, Kathleen Burns, Richard Pugh, Marlies Ostermann, Elisa Kam, H. Bowyer, Nina Smith, M. Templeton,
Abstract Background The Clinical Frailty Scale (CFS) is frequently used to measure frailty in critically ill adults. There is wide variation in the approach to analysing the relationship between the CFS score and mortality after admission to the ICU. This study aimed to evaluate the influence of modelling approach on the association between the CFS score and short-term mortality and quantify the prognostic value of frailty in this context. Methods We analysed data from two multicentre prospective ...
BioMed Central
Christoph Höeller, Burkhard Jansen, Elisabeth Heere‐Ress, Tom Pustelnik, Ulrike Mossbacher, Hermine Schlagbauer‐Wadl, Klaus Wolff, Hubert Pehamberger,
... model system employed (Mantovani et al., 1992Mantovani A. Bottazzi B. Colotta F. Sozzani S. Ruco L. Origin ... al., 1992Avril M.F. Carpentier P. Margulis A. Guillaume J.C. Regression of primary melanoma with metastases. ...
Tópico(s): T-cell and B-cell Immunology
2001 - Elsevier BV | Journal of Investigative Dermatology
David J. Mahoney, Katalin Mikecz, Tariq Ali, Guillaume Mabilleau, Dafna Benayahu, Anna Plaas, Caroline M. Milner, Anthony J. Day, A Sabokbar,
... C. Hirsch E. De Acetis M. Maccagno A. Bottazzi B. Doni A. Bastone A. Mantovani G. Beck ...
Tópico(s): Bone health and treatments
2008 - Elsevier BV | Journal of Biological Chemistry
Alexander M. Kusmanoff, Josephine Martell, Amanda D. Rodewald, Jennifer McGowan, Rob Weary, Leah Carriere, Edward T. Game, Joanna Smith, Melissa Garvey, Hugh P. Possingham, Emma Wiik, Julia Jones, Edwin Pynegar, Patrick Bottazzi, Nigel Asquith, James Gibbons, Andreas Kontoleon, Bron Taylor, Guillaume Chapron, Helen Kopnina, Ewa H. Orlikowska, Joe W. Gray, John Piccolo, Arian D. Wallach, Chelsea Batavia, Marc Bekoff, Shelley M. Alexander, Liv Baker, Louise Boronyak, Adam P. A. Cardilin, Yohay Carmel, Danielle Celermajer, Simon Coghlan, Yara Dahdal, Jonatan J. Gómez, Gisela Kaplan, Oded Keynan, Anton Khalilieh, William S. Lynn, Yamini Narayanan, Sophie Riley, Francisco J. Santiago‐Ávila, Esty Yanco, Miriam A. Zemanova, Daniel Ramp, Reconsidering Humaneness, Jordan O. Hampton, Penny Fisher, Bruce Warburton, Michael L. Nelson, Robert R. Montgomery, Kendi Borona, Herbert Kasozi, Tutilo Mudumba, Mordecai Ogada, Fiona Fidler, Ascelin Gordon, Georgia E. Garrard, Sarah A. Bekessy, Mi Young Yoon, Sung‐Won Son, Sonia Herrando‐Moraira, Cindy G. Tang, Masayuki Maki, Young‐Dong Kim, Jordi López‐Pujol, J. L. Hamrick, Myong Chung, Christian Riisager‐Simonsen, Olivia Rendón, Anders Galatius, Morten Tange Olsen, Nicola Beaumont, Lily M. van Eeden, Kristina M. Slagle, Thomas M. Newsome, Mathew S. Crowther, Chris R. Dickman, Jeremy T. Bruskotter, G. Murray McDonald, M. Roy Wilson, Diogo Veríssimo, Rebecca Twohey, Michaela Clemence, Dean Apistar, Stephen J. Box, Peter C. Butler, Cesar Cadiz, Stuart Campbell, Courtney Cox, Micah Effron, Steven D. Gaines, Raymond Jakub, Roquelito Mancao, Pablo Rojas, Rocky Tirona, Gabriel M. Vianna, Kirsten M. Leong, Ashley Gramza, Christopher A. Lepczyk, Magdalena Lenda, Piotr Skórka, Błażej Mazur, William J. Sutherland, Piotr Tryjanowski, Dawid Moroń, Erik Meijaard, Kerrie A. Wilson, Ariel G. Spanowicz, Fernanda Teixeira, Jochen Jaeger, Krista Kemppinen, Pamela Y. Collins, David Hole, Christopher A. Wolf, William J. Ripple, Leah R. Gerber, Nadiah P. Kristensen, W. B. Seah, Yan Kwek, Yi Chong, T.S. Yeoh, L.S.K. Fung, Hui Berman, Ryan Joseph Tan, Viktor Baranov, Jonas Jourdan, Francesca Pilotto, Rüdiger Wagner, Peter Haase, Jeremy Bird, Robert W. Martin, H. Reşi̇t Akçakaya, James J. Gilroy, Ian J. Burfield, Stephen T. Garnett, Andy Symes, Joseph Taylor, Çafjan Şekercioglu, Stuart H. M. Butchart, Christopher G. Goodchild, Kevin Grisham, Jason B. Belden, Sarah M. Durant, Juan Gallego‐Zamorano, Ana Benítez‐López, Luca Santini, Jelle P. Hilbers, Mark A. J. Huijbregts, Aafke M. Schipper, Javier Nori, Rafael Loyola, Fabricio Villalobos, Kumar P. Mainali, Trevor J. Hefley, Leslie Ries, William F. Fagan, Ron Efrat, Ohad Hatzofe, Oded Berger‐Tal, Efrat Santangeli, Marco Girardello, Evan R. Buechley, André Botha, Enrico Di Minin, Atte Moilanen, Jan Pergl, Petr Pyšek, Franz Essl, Jonathan M. Jeschke, Franck Courchamp, Juergen Geist, Martin Hejda, Ingo Kowarik, Aileen C. Mill, Camille Musseau, Pavel Pipek, Wolf‐Christian Saul, Von Schmalensee, David L. Strayer,
Conservation BiologyVolume 34, Issue 5 p. 1057-1060 Issue InformationFree Access Issue Information - TOC First published: 24 September 2020 https://doi.org/10.1111/cobi.13358AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable ...
Tópico(s): Environmental Sustainability and Technology
2020 - Wiley | Conservation Biology
Guillaume Coqueret, Bertrand Tavin,
We extend the model of Anufriev and Bottazzi (2010) to the case with many assets. We show that under the procedural equilibrium, all assets with nonzero aggregate demand must have the ...
Tópico(s): Economic theories and models
2017 - RELX Group (Netherlands) | SSRN Electronic Journal