Thaís Valéria Milanez, Adriana Bugno, Cecília Cristina Marques dos Santos, Cristina Takami Kanamura, Luzia Setuko Umeda Yamamoto, Raquel dos Anjos Fazioli, Sônia França Correia Barbosa, André Gustavo Tempone Cardoso, Márcia Bittar Atuí, Adele Catarino de Araújo, Alexandre J. da Silva, Antônio Ruffino-Netto, Bernadette Dora Gombossy de Melo Franco, Delia Rodrigues Amaya, Eliseu Alves Waldman, Elizabeth Castañeda, Elizabeth de Souza Nascimento, Fernando Schmitt, Gordon S. Shephard, Guilherme Francisco do Prado, Hans P. van Egmond, Heitor Franco de Andrade Júnior, John R. Gilbert, Juan Carlos Palomino, Lígia Bicudo de Almeida-Muradian, Luz Elena Cano Restreppo, Maria José Mendes Gianini, Marluce Bibbo, Martin E. Munk, Myrna Sabino, Paul W. Flinn, Pedro Paulo Chieffi, Regina Maura Bueno Franco, Susana Córdoba, Terezinha de Jesus Andreoli Pinto, Thales de Brito, Vanessa Yardley, Venâncio Avancini Ferreira Alves, V. A. Maihara, Vera Lúcia Garcia Calich,
Tópico(s): Urban and sociocultural dynamics
2007 - | REVISTA DO INSTITUTO ADOLFO LUTZ
Susanne Rath, L Augusto Trivelin, T R Imbrunito, D M Tomazela, M N De Jesus, P Calvo Marzal, H F De Andrade, A Gustavo Tempone,
Tópico(s): Research on Leishmaniasis Studies
2003 - Institute of Electrical and Electronics Engineers | Scopus
Produção Nacional
Revisado por pares
Andréia Vieira Pereira, Gustavo de Barros, Érika G. Pinto, André G. Tempone, Ricardo de Oliveira Orsi, Lucilene Delazari dos Santos, Sueli Aparecida Calvi, Rui Seabra Ferreira, Daniel C. Pimenta, Benedito Barraviera,
Apis mellifera venom, which has already been recommended as an alternative anti-inflammatory treatment, may be also considered an important source of candidate molecules for biotechnological and biomedical uses, such as the treatment of parasitic diseases.Africanized honeybee venom from Apis mellifera was fractionated by RP-C18-HPLC and the obtained melittin was incubated with promastigotes and intracellular amastigotes of Leishmania (L.) infantum. Cytotoxicity to mice peritoneal macrophages was ...
Tópico(s): Insect and Pesticide Research
2016 - BioMed Central | The Journal of venomous animals and toxins including tropical diseases
... Hendrika Maria te Brake Lucia Martins Teixeira Andre Gustavo Tempone Jeanette W. P. Teo Benno Herman ter Kuile ...
Tópico(s): Cancer and biochemical research
2019 - American Society for Microbiology | Antimicrobial Agents and Chemotherapy
Produção Nacional
Revisado por pares
André Gustavo Carlon, Ben Mansour Dia, Luis Espath, Rafael Holdorf Lopez, Raúl Tempone,
Finding the best setup for experiments is the primary concern for Optimal Experimental Design (OED). Here, we focus on the Bayesian experimental design problem of finding the setup that maximizes the Shannon expected information gain. We use the stochastic gradient descent and its accelerated counterpart, which employs Nesterov's method, to solve the optimization problem in OED. We adapt a restart technique, originally proposed for the acceleration in deterministic optimization, to improve stochastic ...
Tópico(s): Advanced Multi-Objective Optimization Algorithms
2020 - Elsevier BV | Computer Methods in Applied Mechanics and Engineering
Produção Nacional
Revisado por pares
Susana Bassol, Sebastián Carranza‐Lira, Cuauhtémoc Celis-González, Samuel Santoyo, Alfonso Murillo, Norma Martínez, Javier Santos, Victoriano Llaca, Fernanda Río de la Loza, Jesus Zarain, Ângela Maggio da Fonseca, Aroldo F. Camargos, Edmund Chada Baracat, Marcos F.da Sá, Juana Bayo, Liliana Adaro, Carlos Gurucharri, Martha Murga, N. Siseles, F. Sayegh, Antônio Tempone, Luis M. Tempone, R Tozzini, Roberto Boccanera, Carlos Naranjo, Fabio Sánchez, Gustavo Gómez, Stella Blanco, Roberto Reyes-Marquez, Gerhard Albrecht, Pedro Cano Ríos,
Objective: The present study was undertaken to assess the impact, effectiveness and safety of a monophasic hormone replacement treatment (HRT) for continuous use with regards to the clinical effects, bleeding patterns and lipid profile of menopausal women in four Latin American countries. Design: Three hundred and six postmenopausal women with natural menopause and uterus present were recruited. This was a multicentre prospective, clinical trial; the participating countries were Brazil (BR), Colombia ( ...
Tópico(s): Phytoestrogen effects and research
2004 - Elsevier BV | Maturitas
Ivanildo A. Brito, Emerson A. Oliveira, Mariana Helena Chaves, Fernanda Thevenard, André F. Rodrigues‐Oliveira, Gustavo Barbosa‐Reis, Patrı́cia Sartorelli, Diogo Oliveira‐Silva, André G. Tempone, Thais A. Costa‐Silva, João Henrique G. Lago,
In the present work five acetylene derivatives (1-5), including three unknowns (1, 3 and 4), were isolated from seeds of Porcelia macrocarpa (Annonaceae).The structures of isolated compounds were determined as docos-13-yn-21-enoic acid (1), 3-hydroxy-4-methylene-2-(eicos-11'-yn-19'-enyl)but-2-enolide (2), 3-hydroxy-4-methylene-2-(octadec-9'-yn-17'-enyl)but-2-enolide (3), 3-hydroxy-4-methylene-2-(hexadec-7'-yn-15'-enyl)but-2-enolide (4), and (2S,3R,4R)-3-hydroxy-4-methyl-2-(eicos-11'-yn-19'-enyl)butanolide ( ...
Tópico(s): Phytochemical compounds biological activities
2020 - Brazilian Chemical Society | Journal of the Brazilian Chemical Society
André Gustavo Carlon, Luis Espath, Raúl Tempone,
Using quasi-Newton methods in stochastic optimization is not a trivial task given the difficulty of extracting curvature information from the noisy gradients. Moreover, pre-conditioning noisy gradient observations tend to amplify the noise. We propose a Bayesian approach to obtain a Hessian matrix approximation for stochastic optimization that minimizes the secant equations residue while retaining the extreme eigenvalues between a specified range. Thus, the proposed approach assists stochastic gradient ...
Tópico(s): Advanced Optimization Algorithms Research
2024 - Taylor & Francis | Optimization methods & software
Produção Nacional
Revisado por pares
Gustavo da Silva, Kevin F. dos Santos, Aline F. Barcellos, Raquel Sousa, André G. Tempone, João Henrique G. Lago, Luciano Caseli,
Tópico(s): Sesquiterpenes and Asteraceae Studies
2024 - Elsevier BV | Bioorganic Chemistry