Produção Nacional
Revisado por pares
R.N. Montanhini, HR Nocko, Antônio Ostrensky,
... reservoirs of the Paranapanema River, Brazil Roberto Montanhini Neto*, Helder Rafael Nocko, Antonio Ostrensky Integrated Group of Aquaculture and Environmental Studies, Federal University of Paraná, 80035-050, Curitiba, Paraná, Brazil *Corresponding author: roberto.neto@ufpr.br ABSTRACT: The goal of this study ...
Tópico(s): Aquatic Ecosystems and Biodiversity
2015 - Inter-Research | Aquaculture Environment Interactions
Produção Nacional
Revisado por pares
Felipe S. Dantas Silva, Emídio P. Neto, Helder Oliveira, Dênis Rosário, Eduardo Cerqueira, Cristiano Bonato Both, Sherali Zeadally, Augusto Neto,
Long-Range Wide-Area Network (LoRaWAN) enables flexible long-range service communications with low power consumption which is suitable for many IoT applications. The densification of LoRaWAN, which is needed to meet a wide range of IoT networking requirements, poses further challenges. For instance, the deployment of gateways and IoT devices are widely deployed in urban areas, which leads to interference caused by concurrent transmissions on the same channel. In this context, it is crucial to understand ...
Tópico(s): Advanced Wireless Communication Technologies
2021 - Institute of Electrical and Electronics Engineers | IEEE Access
Produção Nacional
Revisado por pares
Paulo Henrique Weckwerth, Carlos Alberto de Magalhães Lopes, Marco Antônio Húngaro Duarte, Ana Carolina Villas Bôas Weckwerth, Carlos Henrique Ferreira Martins, Domingos Lamônica Neto, Hélder Aguiar,
To investigate the microbial etiology of suppurative chronic otitis media (SCOM) in patients with complete cleft lip and palate and isolated cleft palate and to determine the sensitivity of isolated microorganisms to antibiotics by drug diffusion from impregnated discs in agar and the minimum inhibitory concentration of each drug to these microorganisms by drug dilution in agar.Effusion samples of SCOM obtained from 40 patients with cleft lip and palate registered at the Hospital for Rehabilitation ...
Tópico(s): Otolaryngology and Infectious Diseases
2009 - SAGE Publishing | The Cleft Palate-Craniofacial Journal
Produção Nacional
Revisado por pares
Diogo de Souza Rabelo, Valder Steffen, Roberto Mendes Finzi Neto, Helder Barbieri Lacerda,
The impedance-based structural health monitoring method has become a promising and attractive tool for damage identification and is considered a nondestructive evaluation technique. However, conventional impedance-based structural health monitoring studies have mainly focused on structural damage identification but not so much on statistical modeling approaches in order to determine a threshold for the decision making of the damage detection system. In this study, the impedance-based structural ...
Tópico(s): Non-Destructive Testing Techniques
2016 - SAGE Publishing | Structural Health Monitoring
Produção Nacional
Revisado por pares
Raimundo C. Rabelo‐Neto, Helder Belato Espindola Sales, Carlos V. M. Inocêncio, Erika Varga, A. Oszkó, András Erdóhelyi, Fábio B. Noronha, Lisiane V. Mattos,
This work investigated the performance of supported LaNiO3 perovskite-type oxides for the CO2 reforming of methane. The methane and CO2 conversion increased at the beginning of reaction for LaNiO3 and LaNiO3/Al2O3 catalysts. On the other hand, conversion remained quite constant for LaNiO3/CeSiO2. in situ XPS experiments under reaction conditions revealed that the metallic Ni particles were oxidized by CO2 from the feed for LaNiO3 and LaNiO3/Al2O3 catalysts. Ceria support was preferentially oxidized, ...
Tópico(s): Catalysis and Oxidation Reactions
2017 - Elsevier BV | Applied Catalysis B Environment and Energy
Produção Nacional
Revisado por pares
Luiz C. Caires-Júnior, Ernesto Goulart, Uirá Souto Melo, Bruno Henrique Silva Araújo, Lucas Alvizi, Alessandra Soares‐Schanoski, Danyllo Oliveira, Gerson Shigeru Kobayashi, Karina Griesi‐Oliveira, Camila Manso Musso, Murilo Sena Amaral, Lucas F. daSilva, Renato Mancini Astray, Sandra Fernanda Suárez-Patiño, Daniella C. Ventini, Sérgio Gomes da Silva, Guilherme Lopes Yamamoto, Suzana Ezquina, Michel Satya Naslavsky, Kayque A. Telles-Silva, Karina Weinmann, Vanessa van der Linden, Hélio van der Linden, João Ricardo Mendes de Oliveira, Nívia Maria Rodrigues Arrais, Adriana Suely de Oliveira Melo, Thalita Figueiredo, Silvana Santos, Joanna Góes Castro Meira, Saulo Duarte Passos, Roque Pacheco de Almeida, Ana Jovina Barreto Bispo, Ésper A. Cavalheiro, Jorge Kalil, Edécio Cunha‐Neto, Helder I. Nakaya, Robert Andreata‐Santos, Luís Carlos de Souza Ferreira, Sergio Verjovski‐Almeida, Paulo Lee Ho, Maria Rita Passos‐Bueno, Mayana Zatz,
Abstract Congenital Zika syndrome (CZS) causes early brain development impairment by affecting neural progenitor cells (NPCs). Here, we analyze NPCs from three pairs of dizygotic twins discordant for CZS. We compare by RNA-Seq the NPCs derived from CZS-affected and CZS-unaffected twins. Prior to Zika virus (ZIKV) infection the NPCs from CZS babies show a significantly different gene expression signature of mTOR and Wnt pathway regulators, key to a neurodevelopmental program. Following ZIKV in vitro ...
Tópico(s): Viral Infections and Vectors
2018 - Nature Portfolio | Nature Communications
Produção Nacional
Thiago Brito Xavier, Gabriela Monteiro Barbosa, Clarina Louis Silva Meira, Nicolau Conte Neto, Hélder Antônio Rebelo Pontes,
epidemiológicos declarados como pandemia.
Tópico(s): Healthcare during COVID-19 Pandemic
2020 - Brazilian Journal of Development | Brazilian Journal of Health Review
Produção Nacional
Revisado por pares
Paula Paccielli Freire, Alexandre H. C. Marques, G. Baiocchi, Lena F. Schimke, Dennyson Leandro M. Fonseca, Ranieri Coelho Salgado, Igor Salerno Filgueiras, Sarah Maria da Silva Napoleão, Desirée Rodrigues Plaça, Karen Tiemi Akashi, Thiago Dominguez Crespo Hirata, Nadia El Khawanky, Lasse M. Giil, Gustavo Cabral‐Miranda, Robson Francisco Carvalho, Luís Carlos de Souza Ferreira, Antônio Condino‐Neto, Helder I. Nakaya, Igor Jurišica, Hans D. Ochs, Niels Olsen Saraiva Câmara, Vera Lúcia Garcia Calich, Otavio Cabral‐Marques,
The fact that the COVID-19 fatality rate varies by sex and age is poorly understood. Notably, the outcome of SARS-CoV-2 infections mostly depends on the control of cytokine storm and the increasingly recognized pathological role of uncontrolled neutrophil activation. Here, we used an integrative approach with publicly available RNA-Seq data sets of nasopharyngeal swabs and peripheral blood leukocytes from patients with SARS-CoV-2, according to sex and age. Female and young patients infected by SARS- ...
Tópico(s): Immune cells in cancer
2021 - American Society for Clinical Investigation | JCI Insight
Gabriel Zanuto Sakita, Paulo de Mello Tavares Lima, Adibe Luiz Abdalla Filho, Thiago Francisco Ventoso Bompadre, Vagner Ovani, Camila de Miranda e Silva Chaves, Beatriz Elisa Bizzuti, Wilian dos Santos da Costa, Tiago do Prado Paim, Tania Sila Campioni, Pedro de Oliva Neto, Hermann Bremer‐Neto, Hélder Louvandini, Adibe Luiz Abdalla,
Food security and climate change concerns are pressing livestock production industry to seek sustainable practices to increase productivity while reducing the intensity of enteric methane (CH 4 ) emissions. In this scenario, the use of enzyme products in ruminant nutrition may be an important alternative to meet future increased demands for animal products with reduced environmental impacts. The objective of this study was to evaluate the effects of treating forage with a fibrolytic enzymes extract ( ...
Tópico(s): Microbial Metabolites in Food Biotechnology
2022 - Elsevier BV | Animal Feed Science and Technology
Produção Nacional
Revisado por pares
Roberto Montanhini Neto, Helder Rafael Nocko, Antônio Ostrensky,
... 80035-050, Curitiba, Paraná, Brazil. E-mail: roberto.neto@ufpr.brSearch for more papers by this authorHelder Rafael Nocko, Helder Rafael Nocko Integrated Group of Aquaculture and Environmental ... 80035-050, Curitiba, Paraná, Brazil. E-mail: roberto.neto@ufpr.brSearch for more papers by this authorHelder Rafael Nocko, Helder Rafael Nocko Integrated Group of Aquaculture and Environmental ...
Tópico(s): Fish Ecology and Management Studies
2016 - Wiley | Aquaculture Research
Produção Nacional
Revisado por pares
Gabriel Zanuto Sakita, Thiago Francisco Ventoso Bompadre, D. Dineshkumar, Paulo de Mello Tavares Lima, Adibe Luiz Abdalla Filho, Tania Sila Campioni, Pedro de Oliva Neto, Herman Bremer Neto, Hélder Louvandini, Adibe Luiz Abdalla,
Abstract During specific times of the year, especially dry seasons, tropical forages typically have poor nutritional value due to high contents of neutral and acid detergent fibres, and low crude protein in their composition, which may reduce productivity of ruminant livestock production and lead to increased enteric methane (CH 4 ) emissions per unit of generated product in forage‐bases systems. In order to increase fibre degradability and the efficiency of energy utilisation from low‐quality forages, ...
Tópico(s): Microbial Metabolites in Food Biotechnology
2020 - Wiley | Journal of Animal Physiology and Animal Nutrition
Produção Nacional
Revisado por pares
João Mariz Guimarães Neto, Helder Nunes da Cunha, José Machado Moita Neto, G. F. Leal Ferreira,
Tópico(s): Electrostatics and Colloid Interactions
2006 - Springer Science+Business Media | Journal of Sol-Gel Science and Technology
Produção Nacional
Revisado por pares
João Augusto Alves Meira‐Neto, Hélder Marcos Nunes Cândido, Ângela Miazaki, Vanessa Pontara, Marcelo Leandro Bueno, Ricardo Solar, Markus Gastauer,
Abstract Questions The growth–survival trade‐off is a central concept for the conflicting strategies of acquisitive species that grow quicker and conservative species that grow slower. Understanding which, and how, cross‐species functional traits contribute to the growth–survival trade‐off is a key topic for understanding the functioning of tropical forests. The present study aimed to: (a) determine if leaf traits, wood density and fruit size influence the growth–survival trade‐off at the community ...
Tópico(s): Plant Water Relations and Carbon Dynamics
2019 - Wiley | Journal of Vegetation Science
Produção Nacional
Revisado por pares
D. M. B. P. Milori, Helder Vinícius Avanço Galeti, Ladislau Martin‐Neto, Jeferson Dieckow, Martha González-Pérez, Cimélio Bayer, J. C. Salton,
Fluorescence spectroscopy relies on the fluorescence emitted by rigid conjugated systems and thus can be used to assess the soil organic matter (SOM) humification. This technique is generally applied to solution samples of humic substances, and so far no information exists about its applicability to whole untreated soil samples. The laser‐induced fluorescence (LIF) spectroscopy is proposed as a novel technique to assess the organic matter humification in whole soil samples. We sampled the 0‐ to 2. ...
Tópico(s): Soil Geostatistics and Mapping
2005 - Wiley | Soil Science Society of America Journal
Produção Nacional
Revisado por pares
Leonardo R. Pacheco, Helder M. E. Tavares, Miguel Moysés Neto, Márcio Dantas, Luís Rocha, Karina Mota Ribeiro, José Fernando de Castro Figueiredo,
OBJETIVO: Avaliar a incidência e evolução da IRA em pacientes que utilizaram aciclovir por via intravenosa. MÉTODOS: Foram revisados, durante um período de sete meses consecutivos, os prontuários médicos de pacientes acima de 13 anos de idade que usaram aciclovir endovenoso (EV) por cinco dias ou mais. A IRA foi considerada quando a creatinina sérica, previamente normal, aumentava acima de 2 mg/dl. Foi analisado o tipo de tratamento instituído nos casos de IRA e sua evolução. RESULTADOS: Oitenta ...
Tópico(s): Hepatitis C virus research
2005 - Brazilian Medical Association | Revista da Associação Médica Brasileira
Produção Nacional
Revisado por pares
Lucas Lacerda de Souza, Flávia Sirotheau Corrêa Pontes, Hélder Antônio Rebelo Pontes, Nicolau Conte Neto, Waldner Ricardo Souza de Carvalho, Douglas Magno Guimarães,
To integrate the available data published on central mucoepidermoid carcinoma (CMC) into a comprehensive analysis of its clinical aspects, histology, treatment, and prognostic factors.An electronic search was undertaken in July 2017. Eligibility criteria for publications included having clinical, histological, treatment, and time of follow-up data to confirm the diagnosis.In addition, gender, histological grade, conservative treatment, and lymph node metastasis were significant independent prognostic ...
Tópico(s): Soft tissue tumors and treatment
2017 - Elsevier BV | Journal of Cranio-Maxillofacial Surgery
Produção Nacional
Revisado por pares
Lucas Cunha Dias de Rezende, Fernando Fumagalli, Marraiana Schiavon Bortolin, Marianne Garcia de Oliveira, Murilo Helder de Paula, Valter Ferreira de Andrade‐Neto, Flávio da Silva Emery,
1,4-Naphthoquinone derivatives are known to have relevant activities against several parasites. Among the treatment options for malaria, atovaquone, a 1,4-naphthoquinone derivative, is widely applied in the treatment and prophylaxis of such disease. Based on the structure simplification of atovaquone, we designed and synthesized four novel naphthoquinoidal derivatives. The compounds were obtained by the underexplored epoxide-opening reaction of 1,4-naphthoquinone using aniline derivatives as nucleophiles. ...
Tópico(s): Malaria Research and Control
2013 - Elsevier BV | Bioorganic & Medicinal Chemistry Letters
Produção Nacional
Revisado por pares
Concepta McManus, Bruno Freitas Pinto, Rafhael Felipe Saraiva Martins, Hélder Louvandini, Samuel Rezende Paiva, José Braccini Neto, Tiago do Prado Paim,
Three production systems for sheep (Low - L, Medium - M and High - H technology), with increasing technological levels, were studied under conditions in the Center-west of Brazil, to determine economic weights and selection indices of important traits. Receipts and costs were simulated using an economic simulator to calculate the structure of the operational costs. Only characteristics that were responsible for more than 10% of the profit were studied, which included: number of weaned lambs, food consumption ( ...
Tópico(s): Sustainable Agricultural Systems Analysis
2011 - Sociedade Brasileira de Zootecnia | Revista Brasileira de Zootecnia
Produção Nacional
Revisado por pares
Ludmila Rodrigues Pinto Ferreira, Frederico Moraes Ferreira, Laurie Laugier, Sandrine Cabantous, Isabela Cunha Navarro, Darlan da Silva Cândido, Vagner Oliveira Carvalho Rigaud, Juliana Monte Real, Glaucia Vilar Pereira, Isabela Resende Pereira, Leonardo Alexandre de Souza Ruivo, Ramendra Pati Pandey, Marilda Savóia Nascimento, Jorge Kalil, Joseli Lannes-Vieira, Helder I. Nakaya, Christophe Chevillard, Edécio Cunha‐Neto,
Chagas disease, caused by the parasite Trypanosoma cruzi, is endemic in Latin America. Its acute phase is associated with high parasitism, myocarditis and profound myocardial gene expression changes. A chronic phase ensues where 30% develop severe heart lesions. Mouse models of T. cruzi infection have been used to study heart damage in Chagas disease. The aim of this study was to provide an interactome between miRNAs and their targetome in Chagas heart disease by integrating gene and microRNA expression ...
Tópico(s): Viral Infections and Immunology Research
2017 - Nature Portfolio | Scientific Reports
Produção Nacional
Revisado por pares
Laurie Laugier, Ludmila Rodrigues Pinto Ferreira, Frederico Moraes Ferreira, Sandrine Cabantous, Amanda Farage Frade, João Paulo Silva Nunes, R. A. Ribeiro, Pauline Brochet, Priscila Camillo Teixeira, Ronaldo Honorato Barros Santos, Edimar Alcides Bocchi, Fernando Bacal, Darlan da Silva Cândido, Vanessa Escolano Maso, Helder I. Nakaya, Jorge Kalil, Edécio Cunha‐Neto, Christophe Chevillard,
Chronic Chagas disease cardiomyopathy (CCC), an especially aggressive inflammatory dilated cardiomyopathy caused by lifelong infection with the protozoan Trypanosoma cruzi, is a major cause of cardiomyopathy in Latin America. Although chronic myocarditis may play a major pathogenetic role, little is known about the molecular mechanisms responsible for its severity. The aim of this study is to study the genes and microRNAs expression in tissues and their connections in regards to the pathobiological ...
Tópico(s): Galectins and Cancer Biology
2020 - Public Library of Science | PLoS neglected tropical diseases
Produção Nacional
Revisado por pares
Luiz C. Caires-Júnior, Ernesto Goulart, Uirá Souto Melo, Bruno Henrique Silva Araújo, Lucas Alvizi, Alessandra Soares‐Schanoski, Danyllo Oliveira, Gerson Shigeru Kobayashi, Karina Griesi‐Oliveira, Camila Manso Musso, Murilo Sena Amaral, Lucas F. daSilva, Renato Mancini Astray, Sandra Fernanda Suárez-Patiño, Daniella C. Ventini, Sérgio Gomes da Silva, Guilherme Lopes Yamamoto, Suzana Ezquina, Michel Satya Naslavsky, Kayque A. Telles-Silva, Karina Weinmann, Vanessa van der Linden, Hélio van der Linden, João Ricardo Mendes de Oliveira, Nívia Maria Rodrigues Arrais, A.O. Melo, Thalita Figueiredo, Silvana Santos, Joanna Góes Castro Meira, Saulo Duarte Passos, Roque Pacheco de Almeida, Ana Jovina Barreto Bispo, Ésper A. Cavalheiro, Jorge Kalil, Edécio Cunha‐Neto, Helder I. Nakaya, Robert Andreata‐Santos, Luís Carlos de Souza Ferreira, Sergio Verjovski‐Almeida, Paulo Lee Ho, Maria Rita Passos‐Bueno, Mayana Zatz,
The original PDF version of this Article contained errors in the spelling of Luiz Carlos Caires-Júnior, Uirá Souto Melo, Bruno Henrique Silva Araujo, Alessandra Soares-Schanoski, Murilo Sena Amaral, Kayque Alves Telles-Silva, Vanessa van der Linden, Helio van der Linden, João Ricardo Mendes de Oliveira, Nivia Maria Rodrigues Arrais, Joanna Goes Castro Meira, Ana Jovina Barreto Bispo, Esper Abrão Cavalheiro, and Robert Andreata-Santos, which were incorrectly given as Luiz Carlos de Caires Jr., UiráSouto ...
Tópico(s): Mosquito-borne diseases and control
2018 - Nature Portfolio | Nature Communications
Produção Nacional
Revisado por pares
Josemar Alves Caetano, Hélder Seixas Lima, Mateus Santos, Humberto Torres Marques-Neto,
This paper proposes an analysis of political homophily among Twitter users during the 2016 American Presidential Election. We collected 4.9 million tweets of 18,450 users and their contact network from August 2016 to November 2016. We defined six user classes regarding their sentiment towards Donald Trump and Hillary Clinton: whatever, Trump supporter, Hillary supporter, positive, neutral, and negative. Next, we analyzed their political homophily in three scenarios. Firstly, we analyzed the Twitter ...
Tópico(s): Misinformation and Its Impacts
2018 - Springer Science+Business Media | Journal of Internet Services and Applications
Produção Nacional
Revisado por pares
Fernanda Crunfli, Victor Corasolla Carregari, Flávio P. Veras, Lucas Scárdua Silva, Mateus Henrique Nogueira, André Saraiva Leão Marcelo Antunes, Pedro Henrique Vendramini, Aline Gazzola Fragnani Valença, Caroline Brandão‐Teles, Giuliana S. Zuccoli, Guilherme Reis‐de‐Oliveira, Lícia C. Silva-Costa, Verônica M. Saia‐Cereda, Bradley J. Smith, Ana Campos Codo, Gabriela Fabiano de Souza, Stéfanie Primon Muraro, Pierina Lorencini Parise, Daniel A. Toledo-Teixeira, Ícaro Maia Santos de Castro, Bruno Marcel Silva de Melo, Glaucia M. Almeida, Egidi Mayara Silva Firmino, Isadora Marques Paiva, Bruna Manuella Souza Silva, Rafaela Mano Guimarães, Niele Dias Mendes, Raíssa L. Ludwig, Gabriel Palermo Ruiz, Thiago L. Knittel, Gustavo Gastão Davanzo, Jaqueline Aline Gerhardt, Patrícia Brito Rodrigues, Julia Forato, Mariene R. Amorim, Natália S. Brunetti, Matheus Cavalheiro Martini, Maíra Nilson Benatti, Sabrina Setembre Batah, Li Siyuan, Rafael Batista João, Ítalo Karmann Aventurato, Mariana Rabelo de Brito, Maria Julia Mendes, Beatriz Amorim Da Costa, Marina K. M. Alvim, José Roberto da Silva, Lívia Liviane Damião, Iêda Maria Pereira de Sousa, Elessandra Dias da Rocha, Solange Maria Gonçalves, Luiz H. Lopes da Silva, Vanessa Bettini, Brunno Machado de Campos, Guilherme Ludwig, Lucas Tavares, Marjorie Cornejo Pontelli, Rosa Maria Mendes Viana, Ronaldo B. Martins, André Schwambach Vieira, José C. Alves‐Filho, Eurico Arruda, Guilherme Gozzoli Podolsky Gondim, Marcelo Volpon Santos, Luciano Neder, André Damásio, Stevens K. Rehen, Marco Aurélio Ramirez Vinolo, Carolina Demarchi Munhoz, Paulo Louzada‐Júnior, Renê Donizeti Ribeiro de Oliveira, Fernando Q. Cunha, Helder I. Nakaya, Thaís Mauad, Amaro Nunes Duarte‐Neto, Luiz Fernando Ferraz da Silva, Marisa Dolhnikoff, Paulo Hilário Nascimento Saldiva, Alessandro S. Farias, Fernando Cendes, Pedro M. Moraes‐Vieira, Alexandre Todorovic Fabro, Adriano Sebollela, José Luiz Proença‐Módena, Clarissa Lin Yasuda, Marcelo A. Mori, Thiago M. Cunha, Daniel Martins‐de‐Souza,
Although increasing evidence confirms neuropsychiatric manifestations associated mainly with severe COVID-19 infection, long-term neuropsychiatric dysfunction (recently characterized as part of "long COVID-19" syndrome) has been frequently observed after mild infection. We show the spectrum of cerebral impact of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, ranging from long-term alterations in mildly infected individuals (orbitofrontal cortical atrophy, neurocognitive impairment, ...
Tópico(s): COVID-19 and Mental Health
2022 - National Academy of Sciences | Proceedings of the National Academy of Sciences
Produção Nacional
Revisado por pares
Débora Botéquio Moretti, Carolina Rodriguez Jimenez, Heloisa M. Trinca, Raul Machado-Neto, Hélder Louvandini,
Cottonseed has been used as a nutritional alternative in animal production. However, consequences of this nutrient in the progeny is not well characterized. Thus, this work evaluated the effect on the immune and antioxidant status of the progeny of feeding Santa Ines ewe with or without cottonseed. Twenty-four Santa Ines ewes were distributed in two feeding regimes: cottonseed (CS) concentrate (n = 12) and soybean (SB) concentrate (n = 12). After birth, lambs remained with their mothers and blood samples ...
Tópico(s): Peanut Plant Research Studies
2018 - Elsevier BV | Comparative Immunology Microbiology and Infectious Diseases
Produção Nacional
Revisado por pares
Jamille Ramos Oliveira, César Remuzgo, Rafael Rahal Guaragna Machado, Jhosiene Y. Magawa, Isabela Pazotti Daher, Alysson H. Urbanski, G. Schmitz, Helen Andrade Arcuri, Marcelo Alves Ferreira, Greyce Luri Sasahara, Giuliana Xavier de Medeiros, Roberto Carlos Vieira Silva Júnior, Edison Luíz Durigon, Silvia Beatriz Boscardin, Daniela Santoro Rosa, Deborah Schechtman, Helder I. Nakaya, Edécio Cunha‐Neto, Gabriele Gadermaier, Jorge Kalil, Verônica Coelho, Keity Souza Santos,
Introduction Considering the likely need for the development of novel effective vaccines adapted to emerging relevant CoV-2 variants, the increasing knowledge of epitope recognition profile among convalescents and afterwards vaccinated with identification of immunodominant regions may provide important information. Methods We used an RBD peptide microarray to identify IgG and IgA binding regions in serum of 71 COVID-19 convalescents and 18 vaccinated individuals. Results We found a set of immunodominant ...
Tópico(s): Animal Virus Infections Studies
2023 - Frontiers Media | Frontiers in Immunology
Produção Nacional
Revisado por pares
Ana Paula Nunes Rodrigues Alves, João Agostinho Machado‐Neto, Priscila Santos Scheucher, Helder Henrique Paiva, Belinda Pinto Simões, Eduardo Magalhães Rego, Fabı́ola Traina,
Chronic myeloid leukemia (CML) is a clonal myeloproliferative neoplasm of the hematopoietic stem cell characterized by presence of the oncoprotein BCR-ABL1, which have constitutive tyrosine kinase activity. BCR-ABL1 activation induces aurora kinase A (AURKA) and aurora kinase B (AURKB) expression, which are serine-threonine kinases that play an important function in chromosome alignment, segregation and cytokinesis during mitosis. Acquisition of resistance to tyrosine kinase inhibitors has emerged ...
Tópico(s): Microtubule and mitosis dynamics
2016 - Elsevier BV | Leukemia Research
Produção Nacional
Revisado por pares
Concepta McManus, Hélder Louvandini, Helena Cristina Rodrigues Carneiro, Paulo Ricardo Martins Lima, José Braccini Neto,
This study examined the effects of crossbreeding low genetic potential cows of Bos indicus origin characterized by Gyr crossed with Holstein-Friesian and Simmental bulls to produce animals in a low input dual purpose system. The farm is situated near Brasilia, in the savannah region of Brazil. The climate of the region is classified as Aw by Köppen. Data was available on 1580 calvings and completed lactations of cows with three genetic types: Gyr, Holstein-Friesian × Gyr and Simmental × Gyr. The bulls ...
Tópico(s): Livestock Management and Performance Improvement
2011 - Sociedade Brasileira de Zootecnia | Revista Brasileira de Zootecnia
Produção Nacional
Revisado por pares
Flávia Sirotheau Corrêa Pontes, Lucas Lacerda de Souza, Lorena Paula de Paula, Elieser de Melo Galvão Neto, P.F.S. Gonçalves, Hélder Antônio Rebelo Pontes,
To integrate the available data published on central odontogenic fibroma (COF) into a comprehensive analysis of its clinical/radiologic/histological features.An electronic search was undertaken in September 2017. Eligibility criteria included publications reporting cases of COF having enough clinical, radiological and histological information to confirm the diagnosis. Demographic data, lesion site and size, treatment approach, and recurrence were analysed. The cases included in the analysis presented ...
Tópico(s): Soft tissue tumor case studies
2018 - Elsevier BV | Journal of Cranio-Maxillofacial Surgery
Produção Nacional
Revisado por pares
João Paulo Silva Nunes, Pauline Andrieux, Pauline Brochet, Rafael Ribeiro Almeida, Eduardo S. Kitano, André Kenji Honda, Leo Kei Iwai, Débora Andrade-Silva, David Goudenège, Karla Deysiree Alcântara Silva, Raquel de Souza Vieira, Débora Levy, Sérgio Paulo Bydlowski, Frédéric Gallardo, Magali Torres, Edimar Alcides Bocchi, Miguel Mano, Ronaldo Honorato Barros Santos, Fernando Bacal, Pablo Maria Alberto Pomerantzeff, Francisco Rafael Martins Laurindo, Priscila Camillo Teixeira, Helder I. Nakaya, Jorge Kalil, Vincent Procaccio, Christophe Chevillard, Edécio Cunha‐Neto,
Infection by the protozoan Trypanosoma cruzi causes Chagas disease cardiomyopathy (CCC) and can lead to arrhythmia, heart failure and death. Chagas disease affects 8 million people worldwide, and chronic production of the cytokines IFN-γ and TNF-α by T cells together with mitochondrial dysfunction are important players for the poor prognosis of the disease. Mitochondria occupy 40% of the cardiomyocytes volume and produce 95% of cellular ATP that sustain the life-long cycles of heart contraction. ...
Tópico(s): Mitochondrial Function and Pathology
2021 - Frontiers Media | Frontiers in Immunology
Produção Nacional
Revisado por pares
Manuel J. L. F. Rodrigues, Christiano J. S. de Matos, Yi Wei Ho, Hélder Peixoto, Rafael E. P. de Oliveira, Hsin‐Yu Wu, A. H. Castro Neto, José Viana‐Gomes,
Optical frequency conversion via the nonlinear effect of third harmonic generation is shown to be resonantly enhanced in few-layer black phosphorus. This feature is believed to be a consequence of exciton-related resonance, as the enhancement is strongly correlated with the observation of exciton-recombination photoluminescence. Few-layer thicknesses are obtained both via mechanical exfoliation and laser thinning. As a service to our authors and readers, this journal provides supporting information ...
Tópico(s): Perovskite Materials and Applications
2016 - | Advanced Materials