... Editorial: Has Stewart Finally Arrived in the Clinic? Helio Autran de Morais DVM, PhD, DACVIM (Internal Medicine and Cardiology), Helio Autran de Morais DVM, PhD, DACVIM (Internal Medicine and Cardiology) Clinical ... WI 53706Search for more papers by this author Helio Autran de Morais DVM, PhD, DACVIM (Internal Medicine and Cardiology), Helio Autran de Morais DVM, PhD, DACVIM (Internal Medicine and Cardiology) Clinical ...
Tópico(s): Cardiac, Anesthesia and Surgical Outcomes
2005 - Wiley | Journal of Veterinary Internal Medicine

A. Carvalho, C. A. Krug, J. E. T. Mendes, H. Antunes Filho, Hélio de Morais, João Aloisi Sobrinho, Mário Vieira de Morais, Túlio Ribeiro Rocha,
Em um conjunto de cafeeiros existentes em Mundo Novo, hoje Urupês, na região Araraquarense do Estado de São Paulo, foram feitas seleções de vários cafeeiros baseando-se no seu aspecto vegetativo, na produção existente na época da seleção e na provável produção do ano seguinte. Estudou-se a origem da plantação inicial desse café, tanto em Urupês como em Jaú, chegando-se à conclusão de que é provavelmente originário desta última localidade. Progênies do café "Mundo Novo", anteriormente conhecido por " ...
Tópico(s): Rural Development and Agriculture
1952 - INSTITUTO AGRONÔMICO DE CAMPINAS | Bragantia
Sophie Dennison, Frances M. D. Gulland, Martin Haulena, Helio de Morais, Kathleen M. Colegrove,
Nephrolithiasis has rarely been reported in marine mammals. During 2004 and 2005, two cases of nephrolithiasis were diagnosed during routine necropsy examination, one in a northern elephant seal (Mirounga angustirostris) and one in a California sea lion (Zalophus californianus). Nephroliths were found throughout both kidneys during necropsy examination, varying in size from 1–10 mm in diameter in the northern elephant seal and from 1–15 mm in diameter in the California sea lion. Necropsy and histopathology ...
Tópico(s): Reproductive Physiology in Livestock
2007 - American Association of Zoo Veterinarians | Journal of Zoo and Wildlife Medicine
Igor Yankin, Sarah Nemanic, Silvia Funes, Helio de Morais, Elena Gorman, Craig G. Ruaux,
Abstract Background Splenic nodules and heterogeneous parenchyma are seen frequently in abdominal ultrasound examinations of dogs, but the clinical importance of these lesions remains unclear. Objectives To determine whether specific ultrasonographic findings correlate with clinically relevant cytologic diagnoses and determine what sonographic features are correlated with these diagnoses. Another objective was to develop a scoring rubric to help clinicians make decisions on whether or not certain ...
Tópico(s): Virus-based gene therapy research
2019 - Wiley | Journal of Veterinary Internal Medicine

José Tavares‐Neto, Amélia P. A. Travassos da Rosa, Meire Ataide, Hélio Morais-Souza, Pedro Vasconcelos, Jorge Travassos da Rosa,
Na cidade de Uberaba, Estado de Minas Gerais, dos 162 doadores de sangue, 13 (8,0%) apresentaram anticorpos neutralizantes contra o vesiculovirus Piry. Nos indivíduos positivos foi estatisticamente mais freqüente o relato de residência anterior em área rural (p < 0,0001) e em cidades do Estado de São Paulo (p < 0,05).
Tópico(s): Respiratory viral infections research
1990 - UNIVERSIDADE DE SÃO PAULO | Revista do Instituto de Medicina Tropical de São Paulo

Alexander Welker Biondo, Andrea Pires dos Santos, Ana M. S. Guimarães, Rafael Felipe da Costa Vieira, Odilon Vidotto, Daniel de Barros Macieira, Nádia Regina Pereira Almosny, Marcelo Beltrão Molento, Jorge Timenetsky, Helio Autrán de Morais, Félix González, Joanne B. Messick,
Recent studies have been conducted in Brazil using molecular techniques for the detection of hemotrophic mycoplasmas in several mammals. In domestic cats, Mycoplasma haemofelis, "Candidatus M. haemominutum", and "Candidatus M. turicensis" infections have been identified. These species have also been found in free-ranging and captive neotropical felid species. Two canine hemoplasmas, Mycoplasma haemocanis and "Candidatus Mycoplasma haematoparvum", have been identified in dogs. In commercial swine populations, ...
Tópico(s): Viral Infections and Vectors
2009 - Colégio Brasileiro de Parasitologia Veterinaria | Revista Brasileira de Parasitologia Veterinária/Brazilian Journal of Veterinary Parasitology
Helio Autrán de Morais, Jonathan F. Bach, Stephen P. DiBartola,
The recognition and management of acid-base disorders is a commonplace activity in the critical care unit, and the role of weak and strong acids in the genesis of metabolic acid-base disorders is reviewed. The clinical approach to patients with metabolic alkalosis and metabolic acidosis is discussed in this article.
Tópico(s): Potassium and Related Disorders
2008 - Elsevier BV | Veterinary Clinics of North America Small Animal Practice

C. A. V. Serafini, Ghislaine Rosa, Ana M. S. Guimarães, Helio Autrán de Morais, Alexander Welker Biondo,
Animal population estimates are essential for public health services to ensure the success of zoonoses control programmes. Canine and feline populations vary among different regions mainly because of local human income status and type of human residence. Accordingly, the present study estimated the pet population size living in apartments of a vertical neighbourhood in Curitiba, Brazil. We chose a neighbourhood with a predominance of apartment buildings. All apartment buildings were visited, and ...
Tópico(s): Human-Animal Interaction Studies
2008 - Wiley | Zoonoses and Public Health

Andrea Pires dos Santos, Rodrigo Pires dos Santos, Alexander Welker Biondo, José Miguel Dora, Luciano Z. Goldani, Simone Tostes de Oliveira, Ana M. S. Guimarães, Jorge Timenetsky, Helio Autrán de Morais, Félix González, Joanne B. Messick,
Abstract Hemotrophic mycoplasmas infect a variety of mammals. Although infection in humans is rarely reported, an association with an immunocompromised state has been suggested. We report a case of a Mycoplasma haemofelis–like infection in an HIV-positive patient co-infected with Bartonella henselae.
Tópico(s): Vector-borne infectious diseases
2008 - Centers for Disease Control and Prevention | Emerging infectious diseases

Helio Autrán de Morais, Ana M. S. Guimarães, Odilon Vidotto, Aline Baumann, Alexander Welker Biondo, Joanne B. Messick,
The two most common haemotropic Mycoplasma of cats, Mycoplasma haemofelis and 'Candidatus Mycoplasma haemominutum' have been identified using molecular techniques in all continents, except Antarctica. We report the first molecular characterization in South America of a dual infection with M haemofelis and 'Candidatus Mycoplasma haemominutum' in three domestic cats. The 16S ribosomal RNA gene was amplified in three anaemic cats in which haemoplasma organisms were seen attached to the erythrocytes in ...
Tópico(s): Rabies epidemiology and control
2007 - SAGE Publishing | Journal of Feline Medicine and Surgery

Rafael Felipe da Costa Vieira, Alexander Welker Biondo, Ana M. S. Guimarães, Andrea Pires dos Santos, Rodrigo Pires dos Santos, Leonardo Hermes Dutra, Pedro Paulo Vissotto de Paiva Diniz, Helio Autrán de Morais, Joanne B. Messick, Marcelo B. Labruna, Odilon Vidotto,
Ehrlichiosis is a disease caused by rickettsial organisms belonging to the genus Ehrlichia. In Brazil, molecular and serological studies have evaluated the occurrence of Ehrlichia species in dogs, cats, wild animals and humans. Ehrlichia canis is the main species found in dogs in Brazil, although E. ewingii infection has been recently suspected in five dogs. Ehrlichia chaffeensis DNA has been detected and characterized in mash deer, whereas E. muris and E. ruminantium have not yet been identified ...
Tópico(s): Dermatological diseases and infestations
2011 - Colégio Brasileiro de Parasitologia Veterinaria | Revista Brasileira de Parasitologia Veterinária/Brazilian Journal of Veterinary Parasitology

Márcia Mery Kogika, Helio Autrán de Morais,
Hypokalemia is more common than hyperkalemia and usually is caused by excessive losses of potassium from the kidneys or gastrointestinal tract. Serum potassium should be investigated in patients developing chronic or frequent vomiting or diarrhea, marked polyuria, muscle weakness, or unexpected cardiac arrhythmias, as well as in those undergoing therapy with insulin, diuretics, or total parenteral nutrition. Clinical signs develop when serum potassium deficit is moderate or severe.
Tópico(s): Ion Transport and Channel Regulation
2016 - Elsevier BV | Veterinary Clinics of North America Small Animal Practice

Helio Autrán de Morais, Andrea Pires dos Santos, Naíla Cannes do Nascimento, Louise Bach Kmetiuk, David Soeiro Barbosa, Paulo Eduardo Brandão, Ana M. S. Guimarães, Christina Pettan-Brewer, Alexander Welker Biondo,
Severe respiratory syndrome coronavirus 2 (SARS-CoV-2), responsible for the Coronavirus disease 2019 (COVID-19), is the causative infectious agent of the current pandemic. As researchers and health professionals are still learning the capabilities of this virus, public health concerns arise regarding the zoonotic potential of SARS-CoV-2. With millions of people detected with SARS-CoV-2 worldwide, reports of companion animals possibly infected with the virus started to emerge. Therefore, our aim is ...
Tópico(s): Viral gastroenteritis research and epidemiology
2020 - Frontiers Media | Frontiers in Veterinary Science
Jennifer A. Kaae, Helio Autrán de Morais,
This article serves as a quick reference for the anion gap and strong ion gap. Guidelines for analysis and interpretation of changes are presented.
Tópico(s): Electrolyte and hormonal disorders
2008 - Elsevier BV | Veterinary Clinics of North America Small Animal Practice
William W. Muir, Helio S. De Morais Autran, Peter D. Constable,
To evaluate the effects of a hemoglobin-based oxygen carrier (HBOC-301) on left ventricular preload, afterload, contractility, and ventriculo-arterial coupling in anesthetized dogs.A prospective experimental study.Seven adult male dogs weighing 2.3 to 2.7 kg.The study was performed on intact, closed-chest, chloralose-anesthetized dogs. Heart rate, left ventricular end-systolic and end-diastolic volume and pressure, cardiac output, stroke volume, blood resistivity, mean arterial pressure (MAP), dP/ ...
Tópico(s): Nitric Oxide and Endothelin Effects
2000 - Wiley | Veterinary Surgery

Altina Bruna de Souza Barbosa, Louise Bach Kmetiuk, Otávio Carvalho, Ana Pérola Drulla Brandão, Fernando Rodrigo Doline, Sibele Rejane Rangel Silveira Lopes, Douglas Adamoski Meira, Emanuel Maltempi de Souza, Edvaldo da Silva Trindade, Valter A. Baura, David Soeiro Barbosa, Daniel Friguglietti Brandespim, Juliana Arena Galhardo, Christina Pettan-Brewer, Ana M. S. Guimarães, Valéria Dutra, Helio Autrán de Morais, Luciano F. Huergo, Andrea Pires dos Santos, Alexander Welker Biondo,
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-positive pet owners are reported to be a risk factor for infection of their pets; however, the influence of the viral load and associated risks has not been fully established. This study aimed to assess potential association of viral load in owners with the presence of SARS-CoV-2 infection in their dogs. Of 20 SARS-CoV-2-positive pet owners from 13 families in Curitiba, Brazil, 5 of 22 (22.7%) dogs were positive for SARS-CoV-2. Viral presence ...
Tópico(s): Animal Virus Infections Studies
2022 - Elsevier BV | Research in Veterinary Science
Andrea Bohn, Helio Autrán de Morais,
Chloride is an essential element, playing important roles in digestion, muscular activity, regulation of body fluids, and acid-base balance. As the most abundant anion in extracellular fluid, chloride plays a major role in maintaining electroneutrality. Chloride is intrinsically linked to sodium in maintaining osmolality and fluid balance and has an inverse relationship with bicarbonate in maintaining acid-base balance. It is likely because of these close ties that chloride does not get the individual ...
Tópico(s): Renal function and acid-base balance
2016 - Elsevier BV | Veterinary Clinics of North America Small Animal Practice

Helio S. Autran de Morais, Stephen P. DiBartola,
Summary Ventilatory and metabolic compensation to acid‐base disturbances is reviewed. The mechanisms for compensation as well as the values obtained from several studies using normal dogs and dogs with experimentally induced diseases are provided. Compensation is not the same in dogs and human beings. Dogs have a better ability to adapt to most respiratory disorders, and human beings adapt better to metabolic acidosis. In metabolic alkalosis and chronic respiratory acidosis there is no difference ...
Tópico(s): Respiratory Support and Mechanisms
1991 - Wiley | Journal of Veterinary Emergency and Critical Care

Summary The Physiology of chioride ion and its relationship to clinical disorders in small animall practice is reviewed. Chioride is the major anion in the extracellular fluid and is important in the metabolic regulation of acid‐base balance. A new clinical approach is used to assess chloride ion changes after accounting for changes in free water. Using this approach chloride disorders can be divided into corrected and artifactual. Changes in free water are solely responsible for the chioride ion ...
Tópico(s): Animal health and immunology
1992 - Wiley | Journal of Veterinary Emergency and Critical Care
Alexander Welker Biondo, Zonglin L. Liu, Charles E. Wiedmeyer, Helio S. Autran de Morais, D. David Sisson, Philip F. Solter,
Objective—To determine the nucleotide and amino acid sequence of atrial natriuretic peptide (ANP) in cats and its typical regions of cardiac expression. Animals—5 healthy adult mixed-breed cats. Procedure—Total RNA was extracted from samples obtained from the left and right atrium, left and right ventricle, and interventricular septum of each cat. The RNA was used to produce cDNA for sequencing and northern blot analysis. Genomic DNA was extracted from feline blood samples. Polymerase chain reaction ...
Tópico(s): Pulmonary Hypertension Research and Treatments
2002 - American Veterinary Medical Association | American Journal of Veterinary Research

Alexander Welker Biondo, E. J. Ehrhart, D. David Sisson, Barret J. Bulmer, Helio S. Autran de Morais, Phil F. Solter,
Atrial natriuretic peptide (ANP) and brain natriuretic peptide (BNP) are cardiac hormones involved in electrolyte and fluid homeostasis. Our laboratory has investigated the use of ANP and BNP as diagnostic markers of cardiac disease in cats. We hypothesize that the cardiac distribution of ANP and BNP increases in cats with hypertrophic cardiomyopathy (HCM). Accordingly, we evaluated the immunohistochemical distribution of ANP and BNP in hearts of four cats with naturally occurring HCM relative to five ...
Tópico(s): Congenital Heart Disease Studies
2003 - SAGE Publishing | Veterinary Pathology

Ana Sílvia Dagnone, Helio S. Autran de Morais, Marilda Carlos Vidotto, Flávio Shigueru Jojima, Odilon Vidotto,
Tópico(s): Viral Infections and Vectors
2003 - Elsevier BV | Veterinary Parasitology

Pedro Diniz, Helio S. Autran de Morais, Edward B. Breitschwerdt, Denise Saretta Schwartz,
Background: Ehrlichiosis is a multisystemic disease with the potential to cause cardiomyocyte injury in naturally infected dogs. Hypothesis: Myocardial injury occurs in dogs infected with Ehrlichia canis . Animals: One‐hundred and ninety‐four dogs from Brazil with clinical and laboratory abnormalities indicative of ehrlichiosis. Sixteen healthy dogs served as controls. Methods: Electrocardiogram, echocardiogram, noninvasive blood pressure measurement, and serum cardiac troponin I (cTnI) concentrations ...
Tópico(s): Bird parasitology and diseases
2008 - Wiley | Journal of Veterinary Internal Medicine
Pedro Paulo Vissotto de Paiva Diniz, Denise Saretta Schwartz, Helio S. Autran de Morais, Edward B. Breitschwerdt,
For many vector-borne organisms, dogs can be used as sentinels to estimate the risk of human infection. The objective of this study was to use dogs as sentinels for multiple vector-borne organisms in order to evaluate the potential for human infection with these agents in southeastern Brazil. Blood from 198 sick dogs with clinicopathological abnormalities consistent with tick-borne infections were selected at the São Paulo State University Veterinary Teaching Hospital in Botucatu and tested for ...
Tópico(s): Vector-borne infectious diseases
2007 - Mary Ann Liebert, Inc. | Vector-Borne and Zoonotic Diseases

Sílvia Manduca Trapp, Ana Sílvia Dagnone, Odilon Vidotto, Roberta Lemos Freire, Alexandre Mendes Amude, Helio S. Autran de Morais,
Canine ehrlichiosis and babesiosis have a worldwide distribution with geographic variation in prevalence and main clinical manifestations. We prospectively determined seroprevalence of canine babesiosis and ehrlichiosis, and risk factors for seropositivity. Three hundred and eighty-one dogs were randomly selected to represent the canine population at a Veterinary Teaching Hospital in south Brazil (latitude 23 degrees S). Dogs were tested with a point-of-care ELISA for Ehrlichia canis antibodies and ...
Tópico(s): Mosquito-borne diseases and control
2006 - Elsevier BV | Veterinary Parasitology

Sílvia Manduca Trapp, Joanne B. Messick, Odilon Vidotto, Flávio Shigueru Jojima, Helio S. Autran de Morais,
Babesia gibsoni was first recognized in India in 1910. Analysis of 18S rRNA has shown that there are at least three distinct isolates that are morphologically identical. Although organisms similar to B. gibsoni have been identified in peripheral blood smears from one dog in Brazil, this isolate has not been molecularly characterized. Accordingly, we obtained blood samples from 16 dogs with intraerythrocytic inclusion bodies. DNA was extracted and amplified with primers that detect a segment of the ...
Tópico(s): Viral Infections and Vectors
2006 - Elsevier BV | Veterinary Parasitology
Minta L. Keyes, John E. Rush, Helio S. Autran de Morais, C. Guillermo Couto,
Summary The records of 73 dogs with splenic masses were evaluated retrospectively to determine whether ventricular arrhythmias, in the absence of clinically apparent underlying heart disease, were a common clinical finding. Associated clinical, laboratory, and pathologic findings were evaluated to search for clinical predictors of ventricular arrhythmias. Age, breed, weight, sex, coagulation abnormalities, electrolyte abnormalities, and hemoabdomen were unrelated to the development of arrhythmias ( ...
Tópico(s): Cardiac Structural Anomalies and Repair
1993 - Wiley | Journal of Veterinary Emergency and Critical Care

Taís B. Saito, Amauri Alcindo Alfieri, Sheila Rezler Wosiacki, Fábio Juliano Negrão, Helio S. Autran de Morais, Alice Fernandes Alfieri,
In a prospective study we evaluated the use of the reverse transcriptase-polymerase chain reaction (RT-PCR) in urine samples to diagnose canine distemper virus in dogs with progressive neurological disease. A fragment of the nucleoprotein gene of canine distemper virus was amplified from the urine of 22 distemper dogs. The body fluids and leukocytes of 12 asymptomatic dogs were RT-PCR negative. RT-PCR of urine samples was more sensitive than serum and leukocytes and at least as sensitive as cerebrospinal ...
Tópico(s): Animal Disease Management and Epidemiology
2005 - Elsevier BV | Research in Veterinary Science

John M. MacGregor, Maria L. E. Faria, Antony S. Moore, Anthony H. Tobias, Donald D. Brown, Helio S. Autran de Morais,
Abstract Objective —To determine clinical characteristics and clinicopathologic findings, including results of pericardial fluid analysis, and determine the outcome associated with pericardial effusion caused by cardiac lymphoma in dogs. Design —Retrospective case series. Animals —12 dogs. Procedure —Medical records of affected dogs were reviewed for echocardiographic findings, radiographic findings, results of pericardial fluid analysis, clinicopathologic findings, treatment protocols, and outcomes. ...
Tópico(s): Virus-based gene therapy research
2005 - American Veterinary Medical Association | Journal of the American Veterinary Medical Association
Helio S. Autran de Morais, Stephen P. DiBartola, Dennis J. Chew,
Objective To evaluate clinical and pathologic findings in Golden Retrievers with renal dysplasia. Design Retrospective study. Animals 12 young Golden Retrievers with chronic renal disease. Procedure Medical records of affected dogs were evaluated on the basis of clinical findings, laboratory test results, and histologic findings. Results Common clinical findings were vomiting, anorexia, weight loss, polydipsia, and polyuria. Common laboratory findings were azotemia, hyperphosphatemia, hypercholesterolemia, ...
Tópico(s): Pediatric Urology and Nephrology Studies
1996 - American Veterinary Medical Association | Journal of the American Veterinary Medical Association