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Artigo Revisado por pares

Hiromitsu Kiriyama, Michiaki Mori, Yoshiki Nakai, Takuya Shimomura, H. Sasao, Manabu Tanoue, Shuhei Kanazawa, Daisuke Wakai, Fumitaka Sasao, Hajime Okada, I. Daito, Masatoshi Suzuki, S. Kondo, K. Kondo, A. Sugiyama, Paul R. Bolton, Akira Yokoyama, Hiroyuki Daido, S. Kawanishi, T. Kimura, T. Tajima,

Optical parametric chirped-pulse amplification (OPCPA) operation with low gain by seeding with high-energy, clean pulses is shown to significantly improve the contrast to better than 10(-10) to 10(-11) in a high-intensity Ti:sapphire laser system that is based on chirped-pulse amplification. In addition to the high-contrast broadband, high-energy output from the final amplifier is achieved with a flat-topped spatial profile of filling factor near 77%. This is the result of pump beam spatial profile ...

Tópico(s): High-pressure geophysics and materials

2010 - Optica Publishing Group | Optics Letters

Artigo Revisado por pares

Ken Yamada, Ji-Hu Zhang, Xiaoling Xie, Juergen Reinhardt, Amy Qiongshu Xie, Daniel LaSala, Darcy Kohls, David Yowe, Debra Burdick, Hajime Yoshisue, Hiromichi Wakai, Isabel Schmidt, Jason Gunawan, Kayo Yasoshima, Q. Kimberley Yue, Mitsunori Kato, Muneto Mogi, Neeraja Idamakanti, Natasha Kreder, Peter Drueckes, Pramod S. Pandey, Toshio Kawanami, Waanjeng Huang, Yukiko Yagi, Zhan Deng, Hyi-Man Park,

Protein kinases are known for their highly conserved adenosine triphosphate (ATP)-binding site, rendering the discovery of selective inhibitors a major challenge. In theory, allosteric inhibitors can achieve high selectivity by targeting less conserved regions of the kinases, often with an added benefit of retaining efficacy under high physiological ATP concentration. Although often overlooked in favor of ATP-site directed approaches, performing a screen at high ATP concentration or stringent hit ...

Tópico(s): Diabetes Treatment and Management

2016 - American Chemical Society | ACS Chemical Biology

Artigo Acesso aberto

Kazunao Hayashi, Kenya Kamimura, Kazunori Hosaka, Satoshi Ikarashi, Junji Kohisa, Kazuya Takahashi, Kentaro Tominaga, Ken‐ichi Mizuno, Satoru Hashimoto, Junji Yokoyama, Satoshi Yamagiwa, Kazuyasu Takizawa, Toshifumi Wakai, Hajime Umezu, Shuji Terai,

Duodenal gastrointestinal stromal tumors (GISTs) are extremely rare disease entities, and the extraluminal type is difficult to diagnose.These tumors have been misdiagnosed as pancreatic tumors; hence, pancreaticoduodenectomy has been performed, although partial duodenectomy can be

Tópico(s): Gastric Cancer Management and Outcomes

2017 - Baishideng Publishing Group | World Journal of Gastrointestinal Endoscopy

Artigo Acesso aberto Revisado por pares

Tae Sasakabe, Hajime Haimoto, Umegaki, Wakai,

Background: Reports have shown that visceral adipose tissue (VAT) is more closely linked to cardiovascular risk factors (CRFs) than subcutaneous adipose tissue (SAT). We aimed to elucidate preferential abdominal fat loss and the correlations between abdominal fat reductions and changes in CRFs achieved with a moderate low-carbohydrate diet (LCD) in patients with type 2 diabetes (T2DM). Patients and methods: Fifty-two outpatients (28 men and 24 women, mean age ± SD: 60.0 ± 10.5 years) with hemoglobin A 1c ( ...

Tópico(s): Diabetes, Cardiovascular Risks, and Lipoproteins

2011 - Dove Medical Press | Diabetes Metabolic Syndrome and Obesity

Artigo Acesso aberto Revisado por pares

Toshifumi Wakai, Yoshihiro Shirai, Naoyuki Yokoyama, Shigenori Nagakura, Hajime Watanabe, K Hatakeyama,

This study was designed to address whether gallbladder cancer invading the muscle layer (stage pT(1b)) is a local disease and whether radical resection is necessary.A retrospective analysis of 25 patients with pT(1b) gallbladder tumours, 13 of whom underwent simple cholecystectomy and 12 radical resection with regional lymph node dissection, was performed. A total of 147 regional lymph nodes was examined for metastasis. The median follow-up time was 95 months.No patient had blood vessel or perineural ...

Tópico(s): Viral-associated cancers and disorders

2001 - Oxford University Press | British journal of surgery

Artigo Revisado por pares

Tae Sasakabe, Hajime Haimoto, Hiroyuki Umegaki, Kenji Wakai,

The effectiveness of a moderate low-carbohydrate diet (M-LCD) has been demonstrated in terms of glycemic control, body weight and serum lipid profiles. We investigated the effect of a 3-month M-LCD on visceral adipose tissue (VAT) and subcutaneous adipose tissue (SAT), and examined an association between decrease in carbohydrate intake and reduction in abdominal fat among patients with Type 2 diabetes mellitus (T2DM).Seventy-six patients (45 men and 31 women; mean age ± SD: 59.5 ± 11.1 years) with T2DM were ...

Tópico(s): Bariatric Surgery and Outcomes

2015 - Elsevier BV | Metabolism

Artigo Acesso aberto Revisado por pares

Hajime Haimoto, Tae Sasakabe, Kenji Wakai, Hiroyuki Umegaki,

We previously demonstrated that a loosely restricted 45%-carbohydrate diet led to greater reduction in hemoglobin A1c (HbA1c) compared to high-carbohydrate diets in outpatients with mild type 2 diabetes (mean HbA1c level: 7.4%) over 2 years. To determine whether good glycemic control can be achieved with a 30%-carbohydrate diet in severe type 2 diabetes, 33 outpatients (15 males, 18 females, mean age: 59 yrs) with HbA1c levels of 9.0% or above were instructed to follow a low-carbohydrate diet (1852 ...

Tópico(s): Diet, Metabolism, and Disease

2009 - BioMed Central | Nutrition & Metabolism

Artigo Revisado por pares

Hajime Haimoto, Mitsunaga Iwata, Kenji Wakai, Hiroyuki Umegaki,

The aim was to assess the long-term effect of a loose restriction of carbohydrate intake (carbohydrate-reduced diet: CARD) compared to a conventional diet (CD) in type 2 diabetes. One hundred and thirty-three type 2 diabetic outpatients followed the CD (n = 57, 1734 ± 410 kcal, carbohydrate:protein:fat ratio = 57:16:26) or CARD (n = 76, 1773 ± 441 kcal, carbohydrate:protein:fat ratio = 45:18:33) according to their own will, and were followed up for 2 years. Glycemic control, body mass index (BMI), serum cholesterols ...

Tópico(s): Muscle metabolism and nutrition

2007 - Elsevier BV | Diabetes Research and Clinical Practice

Artigo Revisado por pares

K. Abe, B. R. Ko, Y. Arai, Y. Asano, M. Chiba, Yasuo Chiba, M. Daigo, T. Emura, I. Endo, M. Fukawa, T. Fukui, Y. Fukushima, J. Haba, D. Haidt, I. Hayashibara, Y. Hemmi, M. Higuchi, T. Hirose, Y. Hojyo, Y. Homma, Y. Hoshi, Y. Ikegami, N. Ishihara, T. Kamitani, Nobuyuki Kanematsu, J. Kanzaki, R. Kikuchi, T. Kondo, T. Koseki, K. Kubo, H. Kurashige, Takayuki Matsui, M. Minami, K. Miyake, Shigeki Mori, Y. Nagashima, T. Nakamura, I. Nakano, S. Odaka, K. Ogawa, T. Ohama, T. Ohsugi, A. Ono, H. Osabe, Hitoshi Saitô, H. Sakae, H. Sakamoto, S. Sakamoto, M. Sakano, M. Sakuda, N. Sasao, M. Sato, M. Shioden, J. Shirai, F. Suekane, S. Sugimoto, T. Sumiyoshi, Y. Suzuki, Yoshihisa Takada, F. Takasaki, A. Taketani, N. Tamura, R. Tanaka, K. Tobimatsu, T. Tsuboyama, Akira Tsukamoto, S. Uehara, Y. Unno, M. Wakai, Takashi Watanabe, Y. Watase, Y. Yamada, T. Yamagata, T. Yamashita, Hajime Yoshida,

A search for sequential charged leptons decaying into massive neutrinos has been performed at ${E}_{\mathrm{c}.\mathrm{m}.}=56$ GeV at the KEK colliding-beam accelerator TRISTAN. We have found no evidence for the production of the charged heavy leptons for an integrated luminosity of 5.3 ${\mathrm{pb}}^{\ensuremath{-}1}$. A search for stable charged leptons was also conducted yielding null results. A new mass limit on the charged heavy leptons was obtained as a function of the mass of the associated ...

Tópico(s): Neutrino Physics Research

1988 - American Physical Society | Physical Review Letters

Artigo Acesso aberto Revisado por pares

Hajime Haimoto, Sasakabe, Umegaki, Wakai,

Introduction: Urinary albumin excretion (UAE) is a marker of the early phase of diabetic nephropathy. Although a low-carbohydrate diet (LCD) has been shown to effectively improve glycemic control in patients with type 2 diabetes (T2DM), its effects on UAE remain unknown. Patients and methods: A total of 124 patients (mean age ± standard deviation, 61.6 ± 9.2 years) with T2DM were instructed to consume a moderate LCD (1734 ± 416 kcal/d; % carbohydrate:fat:protein = 38:37:19) for 12 months. We measured the levels ...

Tópico(s): Liver Disease Diagnosis and Treatment

2012 - Dove Medical Press | Diabetes Metabolic Syndrome and Obesity

Artigo Revisado por pares

VENUS Collaboration, Koya Abe, Katsuya Amako, Y. Arai, Y. Asano, H. Boerner, M. Chiba, Yasuo Chiba, Motomasa Daigo, T. Emura, I. Endo, M. Fukawa, Toru Fukui, Y. Fukushima, J. Haba, I. Hayashibara, Y. Hemmi, M. Higuchi, T. Hirose, Y. Hojyo, Yasuhiro Homma, Yoshimoto Hoshi, Y. Ikegami, N. Ishihara, T. Kamitani, Nobuyuki Kanematsu, J. Kanzaki, Ryusaburo Kikuchi, Takahiko Kondo, Tadashi Koseki, K. Kubo, H. Kurashige, Keisuke Maehata, Takayuki Matsui, M. Minami, K. Miyake, Shigeki Mori, Yorikiyo Nagashima, Yuji Nakagawa, T. Nakamura, Itsuo Nakano, Yoshiei Noguchi, S. Odaka, Kazuo Ogawa, T. Ohama, Takashi Ohsugi, A. Ono, H. Osabe, Hitoshi Saitô, H. Sakae, H. Sakamoto, S. Sakamoto, M. Sakano, M. Sakuda, N. Sasao, Minoru Sato, M. Shioden, J. Shirai, F. Suekane, Shojiro Sugimoto, T. Sumiyoshi, Y. Suzuki, Yoshihisa Takada, Fumihiko Takasaki, Atsushi Taketani, Norio Tamura, R. Tanaka, Yoshiki Teramoto, Keijiro Tobimatsu, Toru Tsuboyama, Akira Tsukamoto, S. Uehara, Yoshinobu Unno, M. Wakai, M. Wake, Takashi Watanabe, Y. Watase, Yoshikazu Yamada, T. Yamagata, nameToshihiro Yamashita, Hajime Yoshida,

A result of the search for the top quark in e + e - annihilation into hadrons at \(\sqrt{s}=50\) GeV is presented. The experiment has been perforrnxed using the VENUS detector at TRISTAN. No evidence has been found for the production of the top quark. From the study using the event shape of the multihadron events, the upper limit of the production cross section is found to be 16 pb at thcc 95% confidence level.

Tópico(s): Quantum Chromodynamics and Particle Interactions

1987 - Physical Society of Japan | Journal of the Physical Society of Japan

Artigo Revisado por pares

K. Abe, B. R. Ko, Y. Arai, Y. Asano, M. Chiba, Yasuo Chiba, M. Daigo, T. Emura, M. Fukawa, T. Fukui, Y. Fukushima, J. Haba, Y. Hemmi, M. Higuchi, T. Hirose, Y. Hojyo, Y. Homma, Y. Hoshi, Y. Ikegami, N. Ishihara, T. Kamitani, Nobuyuki Kanematsu, J. Kanzaki, R. Kikuchi, T. Kondo, T. Korhonen, T. Koseki, H. Kurashige, Takayuki Matsui, M. Minami, K. Miyake, Shumpei Mori, Y. Nagashima, T. Nakamura, I. Nakano, Y. Narita, S. Odaka, K. Ogawa, T. Ohama, T. Ohsugi, A. Okamoto, A. Ono, Takashi Oyama, H. Sakamoto, M. Sakuda, N. Sasao, M. Sato, M. Shioden, J. Shirai, M. Shirakata, S. Sugimoto, T. Sumiyoshi, A. Suzuki, Y. Suzuki, Yoshihisa Takada, F. Takasaki, A. Taketani, M. Takita, N. Tamura, R. Tanaka, N. Terunuma, K. Tobimatsu, T. Tsuboyama, S. Uehara, Y. Unno, M. Utsumi, M. Wakai, T. Watanabe, Y. Watase, F. Yabuki, Yoichi M. A. Yamada, T. Yamagata, Yasushige Yonezawa, Hajime Yoshida,

We have studied four-jet angular distributions using data collected with the VENUS detector at the KEK ${\mathit{e}}^{+}$${\mathit{e}}^{\mathrm{\ensuremath{-}}}$ collider at TRISTAN at c.m. energies between 54 and 64 GeV. The obseved angular distributions are consistent with QCD, but are inconsistent with the Abelian gluon model at the 5% significance level. We have further obtained 95%-confidence experimental bounds on the fundamental parameters of the SU(${\mathit{N}}_{\mathit{c}}$) local color symmetry.

Tópico(s): Quantum Chromodynamics and Particle Interactions

1991 - American Physical Society | Physical Review Letters

Artigo Revisado por pares

K. Abe, K. Amako, Y. Arai, Y. Asano, M. Chiba, Yasuo Chiba, M. Daigo, T. Emura, I. Endo, M. Fukawa, T. Fukui, Y. Fukushima, J. Haba, I. Hayashibara, Y. Hemmi, M. Higuchi, T. Hirose, Y. Hojyo, Y. Homma, Y. Hoshi, Y. Ikegami, N. Ishihara, T. Kamitani, Nobuyuki Kanematsu, J. Kanzaki, R. Kikuchi, T. Kondo, T. Koseki, K. Kubo, H. Kurashige, Takayuki Matsui, M. Minami, K. Miyake, Shigeki Mori, Y. Nagashima, T. Nakamura, I. Nakano, Y. Narita, S. Odaka, K. Ogawa, T. Ohama, T. Ohsugi, A. Okamoto, A. Ono, H. Osabe, Takashi Oyama, Hitoshi Saitô, H. Sakae, H. Sakamoto, S. Sakamoto, M. Sakano, M. Sakuda, N. Sasao, M. Sato, M. Shioden, J. Shirai, M. Shirakata, F. Suekane, S. Sugimoto, T. Sumiyoshi, A. Suzuki, Y. Suzuki, Yoshihisa Takada, F. Takasaki, A. Taketani, M. Takita, N. Tamura, R. Tanaka, N. Terunuma, K. Tobimatsu, T. Tsuboyama, Akira Tsukamoto, S. Uehara, Y. Unno, M. Utsumi, M. Wakai, Takashi Watanabe, Y. Watase, F. Yabuki, Y. Yamada, T. Yamagata, T. Yamashita, Yasushige Yonezawa, Hajime Yoshida,

We have tested extra Z models in the reactions e+e−→μ+μ−, τ+τ− and hadrons in the energy range 50<s<64GeV using the VENUS detector at the TRISTAN e+e− storage ring. Our data are in good agreement with the standard model prediction (χ2NDf=2.931)). We have obtained 90% confidence-level lower limits of 105, 125 and 231 GeV for the masses of ZΨ, Zη and Zχ bosons which are expected from the E6 grand unified theory. We also place a 90% confidence-level lower limit of 426 GeV for the mass of an extra-Z ...

Tópico(s): Neutrino Physics Research

1990 - Elsevier BV | Physics Letters B

Artigo Acesso aberto Revisado por pares

Yosuke Tajima, Hitoshi Kameyama, Saki Yamada, Ryoma Yagi, Masato Nakano, Masayuki Nagahashi, Yoshifumi Shimada, Jun Sakata, Takashi Kobayashi, Hajime Umezu, Toshifumi Wakai,

Meigs’ syndrome is defined as the co-existence of benign ovarian fibroma or fibroma-like tumor, ascites, and pleural effusion. In contrast, pseudo-Meigs’ syndrome is defined as the co-existence of other ovarian or pelvic tumors, ascites, and pleural effusion. In Meigs’ and pseudo-Meigs’ syndromes, ascites and pleural effusion resolve promptly after the complete resection of the ovarian or pelvic tumor(s). Secondary ovarian tumors from colorectal gastrointestinal metastases rarely cause pseudo-Meigs’ ...

Tópico(s): Hepatocellular Carcinoma Treatment and Prognosis

2016 - BioMed Central | World Journal of Surgical Oncology

Artigo Revisado por pares

K. Abe, B. R. Ko, Y. Arai, Y. Asano, M. Chiba, Yasuo Chiba, M. Daigo, T. Emura, I. Endo, M. Fukawa, T. Fukui, Y. Fukushima, J. Haba, D. Haidt, I. Hayashibara, Y. Hemmi, M. Higuchi, T. Hirose, Y. Hojyo, Y. Homma, Y. Hoshi, Y. Ikegami, N. Ishihara, T. Kamitani, Nobuyuki Kanematsu, J. Kanzaki, R. Kikuchi, T. Kondo, T. Koseki, H. Kurashige, Takayuki Matsui, M. Minami, K. Miyake, Shigeki Mori, Y. Nagashima, T. Nakamura, I. Nakano, Y. Narita, S. Odaka, K. Ogawa, T. Ohama, T. Ohsugi, A. Okamoto, A. Ono, H. Osabe, Takashi Oyama, Hitoshi Saitô, H. Sakae, H. Sakamoto, S. Sakamoto, M. Sakano, M. Sakuda, N. Sasao, M. Sato, M. Shioden, J. Shirai, S. Shirakata, S. Sugimoto, T. Sumiyoshi, S. Suzuki, Y. Suzuki, Yoshihisa Takada, F. Takasaki, A. Taketani, M. Takita, N. Tamura, R. Tanaka, N. Terunuma, K. Tobimatsu, T. Tsuboyama, Akira Tsukamoto, S. Uehara, Y. Unno, M. Utsumi, M. Wakai, Takashi Watanabe, Y. Watase, F. Yabuki, Y. Yamada, T. Yamagata, T. Yamashita, Yasushige Yonezawa, Hajime Yoshida,

A study of single photon events, produced in association with light neutrinos or other weakly interacting neutral particlaes in e+e− collisions, has been performed at √s=54.0–61.4 GeV with the VENUS detector at TRISTAN. No anomalous signal has been observed in a data sample corresponding to an integrated luminosity of 28.2 pb−1. This result indicates that the upper limit on the number of light neutrinos, Nν, is 11 (15) at a 90 (95)% confidence level. Combining this with published results from other ...

Tópico(s): High-Energy Particle Collisions Research

1989 - Elsevier BV | Physics Letters B

Artigo Revisado por pares

K. Abe, K. Amako, Y. Arai, Y. Asano, M. Chiba, Yasuo Chiba, M. Daigo, T. Emura, I. Endo, M. Fukawa, T. Fukui, Y. Fukushima, J. Haba, D. Haidt, I. Hayashibara, Y. Hemmi, M. Higuchi, T. Hirose, Y. Hojyo, Y. Homma, Y. Hoshi, Y. Ikegami, N. Ishihara, T. Kamitani, Nobuyuki Kanematsu, J. Kanzaki, R. Kikuchi, T. Kondo, T. Koseki, K. Kubo, H. Kurashige, Takayuki Matsui, M. Minami, K. Miyake, Shigeki Mori, Y. Nagashima, T. Nakamura, I. Nakano, Y. Narita, S. Odaka, K. Ogawa, T. Ohama, T. Ohsugi, A. Okamoto, Akira Ono, H. Osabe, Takashi Oyama, Hitoshi Saitô, H. Sakae, H. Sakamoto, S. Sakamoto, M. Sakano, M. Sakuda, N. Sasao, M. Sato, M. Shioden, J. Shirai, S. Shirakata, F. Suekane, S. Sugimoto, T. Sumiyoshi, S. Suzuki, Y. Suzuki, Yoshihisa Takada, F. Takasaki, A. Taketani, M. Takita, N. Tamura, R. Tanaka, N. Terunuma, K. Tobimatsu, T. Tsuboyama, Akira Tsukamoto, S. Uehara, Y. Unno, M. Utsumi, M. Wakai, Takashi Watanabe, Y. Watase, F. Yabuki, Y. Yamada, T. Yamagata, T. Yamashita, Yasushige Yonezawa, Hajime Yoshida,

A charge asymmetry has been measured in hadron jets from e+e− annihilation at energies between 52 and 61.4 geV (〈√s〉=57.6 GeV). The measured asymmetry is A=11.4%±2.2%±2.1% and is consistent with the prediction of the standard model of the electroweak theory. By using the differential cross section, lower limits of the compositeness scale in eeqq contact interactions have been determined to be typically a few TeV at 95% CL.

Tópico(s): Quantum Chromodynamics and Particle Interactions

1989 - Elsevier BV | Physics Letters B

Artigo Acesso aberto Revisado por pares

Hiroyuki Isayama, Susumu Tazuma, Norihiro Kokudo, Atsushi Tanaka, Toshio Tsuyuguchi, Takahiro Nakazawa, Kenji Notohara, Suguru Mizuno, Nobuhisa Akamatsu, Masahiro Serikawa, Itaru Naitoh, Yoshiki Hirooka, Toshifumi Wakai, Takao Itoi, Tomoki Ebata, Shinji Okaniwa, Terumi Kamisawa, Hiroki Kawashima, Atsushi Kanno, Keiichi Kubota, Masami Tabata, Michiaki Unno, Hajime Takikawa,

Abstract Background Primary sclerosing cholangitis (PSC) is relatively rare disease and pathogenesis and methods of treatments were still not established. Then, we had conducted the making clinical guidelines to manage patients with PSC based on the literature review and expert opinions. These clinical guidelines were made for the medical doctors on the management of PSC, except child case of PSC. Methods We had employed modified Delphi method. The production committee decided guidelines, strength ...

Tópico(s): Cholangiocarcinoma and Gallbladder Cancer Studies

2018 - Springer Science+Business Media | Journal of Gastroenterology

Artigo Acesso aberto Revisado por pares

Kazuki Moro, Hitoshi Kameyama, Kaoru Abe, Junko Tsuchida, Yosuke Tajima, Hiroshi Ichikawa, Masato Nakano, Mayuko Ikarashi, Masayuki Nagahashi, Yoshifumi Shimada, Kaori Kato, Takeshi Okamoto, Hajime Umezu, Emmanuel Gabriel, Masanori Tsuchida, Toshifumi Wakai,

Neurofibromatosis type 1 (NF1) is an autosomal dominant disease of the skin and soft tissue. Aneurysms associated with NF1 can occur, but a secondary aneurysm rupture is very rare, with very few cases reported in literature. We describe the case of a 67-year-old female with NF1 who underwent endovascular aneurysm repair (EVAR) for an abdominal aortic aneurysm (AAA) rupture. She developed a type Ib endoleak requiring a redo-EVAR. Eighteen days after her primary operation, she was found to have two new ...

Tópico(s): Aortic aneurysm repair treatments

2019 - Springer Nature | Surgical Case Reports

Artigo Acesso aberto Revisado por pares

Hajime Haimoto, Tae Sasakabe, Hiroyuki Umegaki, Kenji Wakai,

A low-carbohydrate diet (LCD) achieves good glycemic control in type 2 diabetes (T2DM) compared with a high-carbohydrate diet. With respect to energy metabolism, acute metabolic responses to high-carbohydrate meals (HCMs) have not been determined in LCD patients with T2DM.We enrolled 31 subjects with T2DM (mean age: 62 yrs, mean hemoglobin A1c level: 6.9%), of whom 13 were on a strict LCD (26% carbohydrate diet), and 18 a moderate one (44% carbohydrate diet). Two isocaloric meals were administered to ...

Tópico(s): Metabolism, Diabetes, and Cancer

2009 - BioMed Central | Nutrition & Metabolism

Artigo Acesso aberto

Hiromitsu Kiriyama, Michiaki Mori, Yoshiki Nakai, Takuya Shimomura, H. Sasao, Momoko Tanaka, Yoshihiro Ochi, Manabu Tanoue, Hajime Okada, Shuji Kondo, Shuhei Kanazawa, A. Sagisaka, I. Daito, Daisuke Wakai, Fumitaka Sasao, Masayuki Suzuki, Hideyuki Kotakai, K. Kondo, A. Sugiyama, S. V. Bulanov, Paul R. Bolton, Hiroyuki Daido, Shunichi Kawanishi, John Collier, Cristina Hernandez–Gomez, C. J. Hooker, Klaus Ertel, Toyoaki Kimura, Toshiki Tajima,

We have developed a femtosecond high-intensity laser system that combines both Ti:sapphire chirped-pulse amplification (CPA) and optical parametric CPA (OPCPA) techniques and produces more than 30 J broadband output energy, indicating the potential for achieving peak powers in excess of 500 TW. With a cleaned high-energy seeded OPCPA preamplifier as a front end in the system, for the compressed pulse without pumping the final amplifier, we found that the temporal contrast in this system exceeds 1010 ...

Tópico(s): High-pressure geophysics and materials

2010 - Optica Publishing Group | Applied Optics

Artigo Revisado por pares

H. Kotaki, I. Daito, M. Kando, Y. Hayashi, K. Kawase, Takashi Kameshima, Yuji Fukuda, Takayuki Homma, J. Ma, L.-M. Chen, T. Zh. Esirkepov, A. S. Pirozhkov, James Koga, Anatory Ya. Faenov, С. А. Пикуз, Hiromitsu Kiriyama, Hajime Okada, Takuya Shimomura, Yoshiki Nakai, Manabu Tanoue, H. Sasao, Daisuke Wakai, H. Matsuura, S. Kondo, Shuhei Kanazawa, A. Sugiyama, Hiroyuki Daido, S. V. Bulanov,

A high stability electron bunch is generated by laser wakefield acceleration with the help of a colliding laser pulse. The wakefield is generated by a laser pulse; the second laser pulse collides with the first pulse at 180° and at 135° realizing optical injection of an electron bunch. The electron bunch has high stability and high reproducibility compared with single pulse electron generation. In the case of 180° collision, special measures have been taken to prevent damage. In the case of 135° ...

Tópico(s): Laser-induced spectroscopy and plasma

2009 - American Physical Society | Physical Review Letters

Artigo Revisado por pares

VENUS Collaboration, Koya Abe, Katsuya Amako, Y. Arai, Y. Asano, H. Boerner, M. Chiba, Yasuo Chiba, Motomasa Daigo, T. Emura, I. Endo, M. Fukawa, Toru Fukui, Y. Fukushima, J. Haba, I. Hayashibara, Y. Hemmi, M. Higuchi, T. Hirose, Y. Hojyo, Yasuhiro Homma, Yoshimoto Hoshi, Y. Ikegami, N. Ishihara, T. Kamitani, Nobuyuki Kanematsu, J. Kanzaki, Ryusaburo Kikuchi, Takahiko Kondo, Tadashi Koseki, K. Kubo, H. Kurashige, Keisuke Maehata, Takayuki Matsui, M. Minami, K. Miyake, Shigeki Mori, Yorikiyo Nagashima, Yuji Nakagawa, T. Nakamura, Itsuo Nakano, Yoshiei Noguchi, S. Odaka, Kazuo Ogawa, T. Ohama, Takashi Ohsugi, A. Ono, H. Osabe, Hitoshi Saitô, H. Sakae, H. Sakamoto, S. Sakamoto, M. Sakano, M. Sakuda, N. Sasao, Minoru Sato, M. Shioden, J. Shirai, F. Suekane, Shojiro Sugimoto, T. Sumiyoshi, Y. Suzuki, Yoshihisa Takada, Fumihiko Takasaki, Atsushi Taketani, Norio Tamura, R. Tanaka, Yoshiki Teramoto, Keijiro Tobimatsu, Toru Tsuboyama, Akira Tsukamoto, S. Uehara, Yoshinobu Unno, M. Wakai, M. Wake, Takashi Watanabe, Y. Watase, Yoshikazu Yamada, T. Yamagata, To shihiro Yamashita, Hajime Yoshida,

The differential cross sections for e + e - → e + e - and e + e - →γγ have been measured at the highest energy of \(\sqrt{s}=52\) GeV in e + e - collisions.The process e + e - → e + e - is well understood within the framework of the standard model of electroweak interactions. The reaction e + e - →γγ is found to be in good agreement with QED. The 95% confidence limits obtained for the QED cut-off parameters are \(\varLambda_{+}>61\) GeV and \(\varLambda_{-}>72\) GeV for e + e - →γγ.

Tópico(s): Quantum Chromodynamics and Particle Interactions

1987 - Physical Society of Japan | Journal of the Physical Society of Japan

Artigo Revisado por pares

K. Abe, K. Amako, Y. Arai, Y. Asano, M. Chiba, Yasuo Chiba, M. Daigo, T. Emura, I. Endo, M. Fukawa, T. Fukui, Y. Fukushima, J. Haba, D. Haidt, I. Hayashibara, Y. Hemmi, M. Higuchi, T. Hirose, Y. Hojo, Y. Homma, Y. Hoshi, Y. Ikegami, N. Ishihara, T. Kamitani, Nobuyuki Kanematsu, J. Kanzaki, R. Kikuchi, T. Kondo, T. Koseki, H. Kurashige, Takayuki Matsui, M. Minami, K. Miyake, Shumpei Mori, Y. Nagashima, T. Nakamura, I. Nakano, Y. Narita, S. Odaka, K. Ogawa, T. Ohama, T. Ohsugi, A. Okamoto, A. Ono, H. Osabe, Takashi Oyama, Hitoshi Saitô, H. Sakae, H. Sakamoto, S. Sakamoto, M. Sakano, M. Sakuda, N. Sasao, M. Sato, M. Shioden, J. Shirai, S. Sugimoto, T. Sumiyoshi, Y. Suzuki, Yoshihisa Takada, F. Takasaki, A. Taketani, N. Tamura, R. Tanaka, N. Terunuma, K. Tobimatsu, T. Tsuboyama, Akira Tsukamoto, S. Uehara, Y. Unno, M. Utsumi, M. Wakai, T. Watanabe, Y. Watase, Y. Yamada, T. Yamagata, T. Yamashita, Yasushige Yonezawa, Hajime Yoshida,

A search for a new charge -(1/3 quark has been carried out at the KEK ${e}^{+}$${e}^{\mathrm{\ensuremath{-}}}$Collider TRISTAN under the assumption of its photonic decay through a flavor-changing neutral current (FCNC). The observed number of multihadronic events with isolated photons is consistent with that expected from the known five quark flavors. Including the usual charged-current decays, limits on the absolute photonic branching ratio and FCNC processes were obtained.

Tópico(s): Quantum Chromodynamics and Particle Interactions

1989 - American Physical Society | Physical Review Letters

Artigo Acesso aberto Revisado por pares

Hajime Haimoto, Shiho Watanabe, Masashi Komeda, Kenji Wakai,

Although postprandial glucose levels largely depend on carbohydrate intake, the impact of carbohydrate and its sources on hemoglobin A1c (HbA1c) levels has not been demonstrated in patients with type 2 diabetes (T2DM) probably because, in previous studies, more than 50% of patients were taking anti-diabetic medication, and the researchers used energy percent of carbohydrate as an indicator of carbohydrate intake.We recruited 125 Japanese men (mean age 58±12 years) and 104 women (mean age 62±10 years) ...

Tópico(s): Nutritional Studies and Diet

2018 - Dove Medical Press | Diabetes Metabolic Syndrome and Obesity

Artigo Revisado por pares

A. Yogo, Katsutoshi Sato, Masaharu Nishikino, M. Mori, T. Teshima, Hodaka Numasaki, M. Murakami, Yusuke Demizu, Shinsuke Akagi, Shin Nagayama, Koichi Ogura, A. Sagisaka, Satoshi Orimo, Mamiko Nishiuchi, A. S. Pirozhkov, M. Ikegami, M. Tampo, H. Sakaki, Kenji Suzuki, I. Daito, Y. Oishi, Hironori Sugiyama, Hiromitsu Kiriyama, Hajime Okada, Shuhei Kanazawa, S. Kondo, Takuya Shimomura, Yoshiki Nakai, Manabu Tanoue, H. Sasao, Daisuke Wakai, Paul R. Bolton, Hiroyuki Daido,

We report the demonstrated irradiation effect of laser-accelerated protons on human cancer cells. In vitro (living) A549 cells are irradiated with quasimonoenergetic proton bunches of 0.8–2.4 MeV with a single bunch duration of 15 ns. Irradiation with the proton dose of 20 Gy results in a distinct formation of γ-H2AX foci as an indicator of DNA double-strand breaks generated in the cancer cells. This is a pioneering result that points to future investigations of the radiobiological effects of laser- ...

Tópico(s): Nuclear Physics and Applications

2009 - American Institute of Physics | Applied Physics Letters