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62 resultados

Acesso aberto

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Imagens Acesso aberto

... Name Is the Legend of a Discourse about "Hannya"(Prajna) between the Priest Seikutsu and Matsudaira Fumai, ...

0000 - Gale Group | NCCO Photography

Artigo Acesso aberto

N. Yamazaki, Koji YAWATA, H Hannya, Eiichi KIMURA,

A case of relapsing polychondritis complicated with aortic insufficiency is described in detail.Clinical characteristics of this disease are systemic inflammatory involvement of cartilages, often complicated with conjunctivitis, scleritis, iritis, otitis interna and otitis media. Acute exacerbation and spontaneous remission of systemic chondritis are characteristic.The etiology is still obscure, but according to Pearson, an unusual hypersensitive direct reaction to cartilage, sclera and membranes ...

Tópico(s): Coagulation, Bradykinin, Polyphosphates, and Angioedema

1966 - Japanese Heart Journal Assoc | Japanese Heart Journal

Imagens Acesso aberto

... Umagaeshi along the Zigzag Slope. On the Way, Hannya Falls and Hoto Falls Can Be Seen. The ...

0000 - Gale Group | NCCO Photography

Artigo Acesso aberto Revisado por pares

Asuka Hannya, Taku Nishimura, Isao Matsushita, Jun Tsubota, Yoshikazu Kawata,

The alkaliphilic, halophilic bacterium Halomonas sp. KM-1 can utilize glucose for the intracellular storage of the bioplastic poly-(R)-3-hydroxybutyric acid (PHB) and extracellular secretion of pyruvate under aerobic conditions. In this study, we investigated the effects of sodium chloride concentration on PHB accumulation and pyruvate secretion in the KM-1 strain and, unexpectedly, observed that oxaloacetate, an important intermediate chemical in the TCA cycle, glycogenesis, and aspartic acid biosynthesis, ...

Tópico(s): Enzyme Production and Characterization

2017 - Springer Nature | AMB Express

Artigo Acesso aberto Revisado por pares

Kengo Sasaki, Daisuke Sasaki, Asuka Hannya, Jun Tsubota, Akihiko Kondo,

Abstract The ketone body D-β-hydroxybutyrate (DBHB) has gained attention owing to its cellular signalling function; however, its effect on the human colonic microbiota remains unclear. Here, DBHB dynamics in the human colon were investigated using an in vitro colonic microbiota model, which maintained most of the operational taxonomic units detected in the original faeces. Over 54% of 0.41% (w/v) DBHB was metabolised by microbiota models originating from seven faecal samples after 30 h of fermentation ( ...

Tópico(s): Digestive system and related health

2020 - Nature Portfolio | Scientific Reports

Artigo Acesso aberto Revisado por pares

Georgina I. López-Cortés, Miryam Palacios-Pérez, Gabriel S. Zamudio, Hannya F. Veledíaz, Enrique Ortega, Marco V. José,

Abstract As the SARS-CoV-2 has spread and the pandemic has dragged on, the virus continued to evolve rapidly resulting in the emergence of new highly transmissible variants that can be of public health concern. The evolutionary mechanisms that drove this rapid diversity are not well understood but neutral evolution should open the first insight. The neutral theory of evolution states that most mutations in the nucleic acid sequences are random and they can be fixed or disappear by purifying selection. ...

Tópico(s): Viral gastroenteritis research and epidemiology

2021 - Nature Portfolio | Scientific Reports

Artigo Acesso aberto Revisado por pares

Georgina I. López-Cortés, Miryam Palacios-Pérez, Hannya F. Veledíaz, Margarita M. Hernández-Aguilar, Gerardo R. López-Hernández, Gabriel S. Zamudio, Marco V. José,

The global scale of the COVID-19 pandemic has demonstrated the evolution of SARS-CoV-2 and the clues of adaptation. After two years and two months since the declaration of the pandemic, several variants have emerged and become fixed in the human population thanks to extrinsic selective pressures but also to the inherent mutational capacity of the virus. Here, we applied a neutral substitution evolution test to the spike (S) protein of Omicron’s protein and compared it to the others’ variant of concern ( ...

Tópico(s): Protein Structure and Dynamics

2022 - Multidisciplinary Digital Publishing Institute | Vaccines

Revisão Acesso aberto Revisado por pares

David A. Smith, Sohan Jheeta, Hannya V. Fuentes, Miryam Palacios-Pérez,

Non-communicable diseases are those conditions to which causative infectious agents cannot readily be assigned. It is increasingly likely that at least some of these conditions are due to the breakdown of the previously mutualistic intestinal microbiota under the influence of a polluted, biocide-rich, environment. Following the mid-20th century African studies of Denis Burkitt, the environmental cause of conditions such as obesity has been ascribed to the absence of sufficient fibre in the modern ...

Tópico(s): Digestive system and related health

2022 - Multidisciplinary Digital Publishing Institute | Life

Artigo Acesso aberto Revisado por pares

Kohji Yamada, Ryusuke Kizawa, Ayano Yoshida, Rei Koizumi, Saya Motohashi, Yuya Shimoyama, Yoshito Hannya, Saishu Yoshida, Tsunekazu Oikawa, Masayuki Shimoda, Kiyotsugu Yoshida,

Protein kinase C delta (PKCδ) is a multifunctional PKC family member and has been implicated in many types of cancers, including liver cancer. Recently, we have reported that PKCδ is secreted from liver cancer cells, and involved in cell proliferation and tumor growth. However, it remains unclear whether the extracellular PKCδ directly regulates cell surface growth factor receptors. Here, we identify epidermal growth factor receptor (EGFR) as a novel interacting protein of the cell surface PKCδ in ...

Tópico(s): PI3K/AKT/mTOR signaling in cancer

2022 - Wiley | Cancer Science

Artigo Revisado por pares

Masayo Hirano, Hiromi Ogita‐Nakanishi, Wakako Miyachi, Natsuki Hannya, Yumiko Yamamoto‐Kimoto, Kanji Sakurai, Masako Miyoshi‐Higashino, Junko Tashiro‐Yamaji, Ryuji Kato, Yoshio Ijiri, Kazuhiko Tanaka, Atsuko Kanazawa, Tetsuya Terada, Ryo Kawata, Hiroshi Takenaka, Takahiro Kubota, Ryotaro Yoshida,

The production of allergen-specific IgE antibodies (Abs) in allergen-sensitized patients or animals has a mutual relationship with the immunologic response leading to allergic rhinitis. We recently reported that, after an intranasal injection of cedar pollen into mice, an interleukin-4 (IL-4)-dependent increase in serum nonspecific IgE Abs was a prerequisite for the production of serum allergen-specific IgE Abs. Here, we explored which lymphoid organs were responsive to the intranasally injected allergen ...

Tópico(s): Dermatology and Skin Diseases

2012 - Wiley | Microbiology and Immunology

Artigo Acesso aberto Revisado por pares

Yusni Atifah, Mutiara Lubis, Laila Tussifah Lubis, Amsar Maulana,

... Residu pestisida pada Sungai Batang Gadis yang ditemukan hannya pada titik lokasi yang ditemukan daerah pertanian disepanjang ...

Tópico(s): Dengue and Mosquito Control Research

2019 - UHAMKA Press | BIOEDUSCIENCE

Artigo Acesso aberto

Hiroya Enomoto, Katsuhito Suwa, Nana Takeuchi, Yoshito Hannya, Yuhei Tsukazaki, Takuro Ushigome, Tomoyoshi Okamoto, Ken Eto,

The outlet obstruction (OO) rate is 5.4-18.4% after defunctioning ileostomy (DI) following rectal cancer resection to reduce the incidence and severity of anastomotic leakage; OO affects a patient's quality of life and prolongs hospitalization.A retrospective analysis was performed of patients who underwent anterior rectal resection and DI for rectal cancer.Among 100 patients undergoing anterior rectal resection with DI for rectal cancer, 28 (28%) developed OO. Anastomotic leakage and a rectus abdominis ...

Tópico(s): Anorectal Disease Treatments and Outcomes

2021 - | Cancer Diagnosis & Prognosis

Revisão Acesso aberto Revisado por pares

Georgina I. López-Cortés, Miryam Palacios-Pérez, Margarita M. Hernández-Aguilar, Hannya F. Veledíaz, Marco V. José,

Coronaviruses interact with protein or carbohydrate receptors through their spike proteins to infect cells. Even if the known protein receptors for these viruses have no evolutionary relationships, they do share ontological commonalities that the virus might leverage to exacerbate the pathophysiology. ANPEP/CD13, DPP IV/CD26, and ACE2 are the three protein receptors that are known to be exploited by several human coronaviruses. These receptors are moonlighting enzymes involved in several physiological ...

Tópico(s): Lung Cancer Research Studies

2023 - Multidisciplinary Digital Publishing Institute | Vaccines

Artigo Acesso aberto

Shojun Hatsuzaki,

Tópico(s): Pharmacy and Medical Practices

1962 - Japanese Association of Indian and Buddhist Studies | JOURNAL OF INDIAN AND BUDDHIST STUDIES (INDOGAKU BUKKYOGAKU KENKYU)

Artigo Acesso aberto

Shokan OSAWA,

Tópico(s): Urban and spatial planning

2008 - Japanese Association of Indian and Buddhist Studies | JOURNAL OF INDIAN AND BUDDHIST STUDIES (INDOGAKU BUKKYOGAKU KENKYU)

Artigo Acesso aberto

Haruo Isono, Go YOKOZAWA, Takato KURODA, Apurva Kumar,

Tópico(s): EEG and Brain-Computer Interfaces

2014 - Japan Human Factors and Ergonomics Society | The Japanese Journal of Ergonomics

Artigo Acesso aberto

Nobuyuki Nakajima, Yuko HANNYA,

ファジィ理論の応用は工学の分野から始まったが, 最近では非工学分野への進出に目ざましいものがある.ことに, 評価, すなわち, 個々の項目に対する評価を統合して1つの総合評価値とするための方法としてファジィ理論の有用性が注目されるようになってきている. 本論文では評価へのファジィ推論法の応用について報告する.ことに制御と推論の質的相違について論じ, その相違がファジィ推論法およびルールの設計にどのような差をもたらすかについてくわしく調べる.また, 応用例「満足度を考慮したデータ検索システム」を紹介する.

Tópico(s): Educational Technology and Assessment

1993 - | Journal of Japan Society for Fuzzy Theory and Systems

Artigo Acesso aberto

Motomasa Daigo, Nobuyuki Nakajima, Yuko HANNYA,

本論文では, 顧客の購買行動について分析し, それを支援する商品購入支援システムの構築について論じる。これは前論文で提案した商品検索システムを発展させて, 顧客の選択に便利な様に, 希望条件を自動的に変更して再検索を行い, 提示物件数を適正な数に調節する機能を持つ様にしたシステムである。また, 応用例「中古車購入支援システム」の試作を行ったので, その紹介も併せて行う。

Tópico(s): Big Data and Business Intelligence

1995 - | Journal of Japan Society for Fuzzy Theory and Systems

Artigo Acesso aberto Brasil Produção Nacional Revisado por pares

Maria Inês Gandolfo Conceição, Hannya Herrera Cardona, Jaqueline Tavares de Assis, Rebeca Rocha Mohr, María Fátima Olivier Sudbrack, Carol Strike,

RESUMO Objetivando identificar o perfil de pacientes ambulatoriais que procuram tratamento para problemas relacionados com crack em Brasília, 132 usuários que recebem serviços psicológicos preencheram o Questionário sobre o Perfil de Consumo de Crack e o Cocaine Craving Questionnaire-Brief. Os participantes eram homens (83,6%), solteiros (38,8%) e possuíam residência (100%). O primeiro uso foi motivado pela curiosidade (65,9%), influência dos pares (58,3%) e fácil acesso (50,8%). A maioria (65,2%) relatou ...

Tópico(s): Psychology and Mental Health

2016 - UNIVERSIDADE DE BRASÍLIA | Psicologia Teoria e Pesquisa

Artigo Revisado por pares

Yayah Karyanah,

... the respondents, but who regularly do antenatal care hannya 22%. The need for increased counseling by the ... dari responden, namun yang teratur melakukan antenatal care hannya 22%. Perlunya peningkatan materi penyuluhan oleh Dinas Kesehatan ...

Tópico(s): Methodologies in Health Research and Practice

2018 - UNIVERSIDADE FEDERAL DE PELOTAS | Journal of Nursing and Health

Artigo Acesso aberto Revisado por pares

Kohji Yamada, Yoshito Hannya, Tsunekazu Oikawa, Ayano Yoshida, Kuniko Katagiri, Saishu Yoshida, Rei Koizumi, Naoko Tago, Yuya Shimoyama, Akira Kawamura, Yuta Mochimaru, Ken Eto, Kiyotsugu Yoshida,

Extended-synaptotagmin 1 (E-Syt1) is an endoplasmic reticulum membrane protein that is involved in cellular lipid transport. Our previous study identified E-Syt1 as a key factor for the unconventional protein secretion of cytoplasmic proteins in liver cancer, such as protein kinase C delta (PKCδ); however, it is unclear whether E-Syt1 is involved in tumorigenesis. Here, we showed that E-Syt1 contributes to the tumorigenic potential of liver cancer cells. E-Syt1 depletion significantly suppressed the ...

Tópico(s): Cellular transport and secretion

2023 - Multidisciplinary Digital Publishing Institute | Molecules

Artigo Acesso aberto Revisado por pares

Yuya Shimoyama, Kohji Yamada, Saishu Yoshida, Akira Kawamura, Yoshito Hannya, Yuta Imaizumi, Tomotaka Kumamoto, Yasuhiro Takeda, Masayuki Shimoda, Ken Eto, Kiyotsugu Yoshida,

Protein kinase C delta (PKCδ) is a multifunctional serine-threonine kinase implicated in cell proliferation, differentiation, tumorigenesis, and therapeutic resistance. However, the molecular mechanism of PKCδ in colorectal cancer (CRC) remains unclear. In this study, we showed that PKCδ acts as a negative regulator of cellular senescence in p53 wild-type (wt-p53) CRC. Immunohistochemical analysis revealed that PKCδ levels in human CRC tissues were higher than those in the surrounding normal tissues. ...

Tópico(s): Telomeres, Telomerase, and Senescence

2023 - Wiley | Cancer Science

Artigo Acesso aberto Revisado por pares

T. Nogami,

... etc.), and Demon masks (Beshimi, Shikami, Shishi-guchi, Hannya, fa, etc.). These are, generally speaking, imitation of ...

Tópico(s): Italian Fascism and Post-war Society

1929 - The Japanese Psychological Association | The Japanese journal of psychology

Artigo

Susan Flakes,

... Japanese discipline, performed their synthesis of those disciplines, Hannya Shingyo (Beyond Wisdom), on the Anspacher stage at ...

Tópico(s): Korean Peninsula Historical and Political Studies

1975 - The MIT Press | The Drama Review TDR

Artigo Acesso aberto

Nobuyuki Nakajima, Motomasa Daigo, Yuko HANNYA,

近年ファジィ理論を用いた商品選択支援システムの開発が目につくようになった.本論文ではこれらのシステムを, 商品の選択を支援するシステムという観点から論じる.商品選択支援システムはデータ検索システムと意思決定支援システムの2つの側面をもち, しかもそのどちらとも異なるシステムである.それらの相違点について考察し, 商品選択支援システムの一般的な構築法について論じる.

Tópico(s): Multi-Criteria Decision Making

1996 - | Journal of Japan Society for Fuzzy Theory and Systems

Artigo Revisado por pares

Yayah Karyanah,

... the respondents, but who regularly do antenatal care hannya 22%. The need for increased counseling by the ...

Tópico(s): Global Maternal and Child Health

2018 - UNIVERSIDADE FEDERAL DE PELOTAS | Journal of Nursing and Health

Artigo Acesso aberto

Iskandar Yasin, Agus Priyanto,

... serpihan yang tidak berfungsi lagi sehingga oleh masyarakat hannya dibuang atau untuk kayu bakar. Jika sampah-sampah ...

Tópico(s): Geotechnical and construction materials studies

2019 - | Science Tech Jurnal Ilmu Pengetahuan dan Teknologi

Artigo Revisado por pares

Gary Watt,

... his actor son, Luca. The third is the hannya mask of traditional Japanese Noh theatre, which is ...

Tópico(s): Law in Society and Culture

2021 - | Law/text/culture

Artigo Revisado por pares

Chrystyna Dail,

... duality is perhaps best represented through the Japanese Hannya mask present in Noh and in Balinese performances ...

Tópico(s): Folklore, Mythology, and Literature Studies

2021 - | Theatre history studies