Bin Lin, Martin Braster, Boris M. van Breukelen, Henk W. van Verseveld, Hans V. Westerhoff, Wilfred F. M. Röling,
Relationships between community composition of the iron-reducing Geobacteraceae, pollution levels, and the occurrence of biodegradation were established for an iron-reducing aquifer polluted with landfill leachate by using cultivation-independent Geobacteraceae 16S rRNA gene-targeting techniques. Numerical analysis of denaturing gradient gel electrophoresis (DGGE) profiles and sequencing revealed a high Geobacteraceae diversity and showed that community composition within the leachate plume differed ...
Tópico(s): Mine drainage and remediation techniques
2005 - American Society for Microbiology | Applied and Environmental Microbiology
Liang Yu, Joachim Rozemeijer, Ype van der Velde, Boris M. van Breukelen, Maarten Ouboter, Hans Peter Broers,
Urban areas in coastal lowlands host a significant part of the world's population. In these areas, cities have often expanded to unfavorable locations that have to be drained or where excess rain water and groundwater need to be pumped away in order to maintain dry feet for its citizens. As a result, groundwater seepage influences surface water quality in many of such urban lowland catchments. This study aims at identifying the flow routes and mixing processes that control surface water quality ...
Tópico(s): Hydrology and Watershed Management Studies
2019 - Elsevier BV | The Science of The Total Environment
Stefanie Lutz, Ilja van Meerveld, M. J. Waterloo, Hans Peter Broers, Boris M. van Breukelen,
Abstract. Compound-specific stable isotope analysis (CSIA) has, in combination with model-assisted interpretation, proven to be a valuable approach to quantify the extent of organic contaminant degradation in groundwater systems. CSIA data may also provide insights into the origin and transformation of diffuse pollutants, such as pesticides and nitrate, at the catchment scale. While CSIA methods for pesticides have increasingly become available, they have not yet been deployed to interpret isotope ...
Tópico(s): Pharmaceutical and Antibiotic Environmental Impacts
2013 - Copernicus Publications | Hydrology and earth system sciences
Wilfred F. M. Röling, Boris M. van Breukelen, Frank J. Bruggeman, Hans V. Westerhoff,
Summary Identification of the functional groups of microorganisms that are predominantly in control of fluxes through, and concentrations in, microbial networks would benefit microbial ecology and environmental biotechnology: the properties of those controlling microorganisms could be studied or monitored specifically or their activity could be modulated in attempts to manipulate the behaviour of such networks. Herein we present ecological control analysis (ECA) as a versatile mathematical framework ...
Tópico(s): Microbial bioremediation and biosurfactants
2006 - Wiley | Environmental Microbiology
Liang Yu, Joachim Rozemeijer, Boris M. van Breukelen, Maarten Ouboter, Corné van der Vlugt, Hans Peter Broers,
Abstract. The Amsterdam area, a highly manipulated delta area formed by polders and reclaimed lakes, struggles with high nutrient levels in its surface water system. The polders receive spatially and temporally variable amounts of water and nutrients via surface runoff, groundwater seepage, sewer leakage, and via water inlets from upstream polders. Diffuse anthropogenic sources, such as manure and fertiliser use and atmospheric deposition, add to the water quality problems in the polders. The major ...
Tópico(s): Groundwater and Isotope Geochemistry
2018 - Copernicus Publications | Hydrology and earth system sciences
Liang Yu, Joachim Rozemeijer, Hans Peter Broers, Boris M. van Breukelen, Jack J. Middelburg, Maarten Ouboter, Ype van der Velde,
Abstract. Eutrophication of water bodies has been a problem causing severe degradation of water quality in cities. To gain mechanistic understanding of the temporal dynamics of nitrogen (N) and phosphorus (P) in a groundwater-fed low-lying urban polder, we applied high-frequency monitoring in Geuzenveld, a polder in the city of Amsterdam. The high-frequency monitoring equipment was installed at the pumping station where water leaves the polder. From March 2016 to June 2017, total phosphorus (TP), ammonium ( ...
Tópico(s): Hydrology and Watershed Management Studies
2021 - Copernicus Publications | Hydrology and earth system sciences
D.F. van Breukelen-van der Stoep, D. van Zeben, Boudewijn Klop, Gert‐Jan M. van de Geijn, Hans J. W. Janssen, Noëlle van der Meulen, Marijke A. de Vries, M. Hazes, Erwin Birnie, Manuel Castro Cabezas,
Objective . To investigate the prevalence of underdiagnosis and undertreatment of traditional cardiovascular risk factors in RA patients. Methods . RA patients ⩽70 years of age without cardiovascular disease (CVD) or diabetes mellitus were included. Systolic blood pressure and a fasting lipid profile were measured. The 10-year CVD risk was estimated using the Dutch Cardiovascular Risk Management (CVRM) guideline and EULAR modifications of the Systemic Coronary Risk Evaluation tables. Results . A total of ...
Tópico(s): Hepatitis C virus research
2016 - Oxford University Press | Lara D. Veeken
D.F. van Breukelen-van der Stoep, D. van Zeben, Boudewijn Klop, Gert‐Jan M. van de Geijn, Hans J. W. Janssen, M. Hazes, Erwin Birnie, Noëlle van der Meulen, Marijke A. de Vries, Manuel Castro Cabezas,
Objectives Rheumatoid arthritis (RA) has been identified as an independent cardiovascular risk factor. The importance of risk factors such as hypertension and hyperlipidemia in the generation of atherosclerosis in RA patients is unclear. This study analyzed clinical parameters associated with carotid intima media thickness (cIMT) in patients with RA. Methods Subjects with RA and healthy controls without RA, both without known cardiovascular disease, were included. Participants underwent a standard ...
Tópico(s): Atherosclerosis and Cardiovascular Diseases
2015 - Public Library of Science | PLoS ONE
Rainer U. Meckenstock, Martin Elsner, Christian Griebler, Tillmann Lueders, Christine Stumpp, Jens Aamand, Spiros N. Agathos, Hans‐Jørgen Albrechtsen, Leen Bastiaens, Poul Løgstrup Bjerg, Nico Boon, Winnie Dejonghe, Wei E. Huang, Susanne I. Schmidt, Erik Smolders, Sebastian R. Sørensen, Dirk Springael, Boris M. van Breukelen,
... Lueders○, Christine Stumpp○, Jens Aamand‡, Spiros N. Agathos§, Hans-Jørgen Albrechtsen∥, Leen Bastiaens⊥, Poul L. Bjerg∥, Nico Boon∇, Winnie Dejonghe⊥, Wei E. Huang◆, Susanne I. Schmidt¶, Erik Smolders∞, Sebastian R. Sørensen‡, Dirk Springael∞, and Boris M. van Breukelen#View Author Information† University of Duisburg-Essen, Biofilm ...
Tópico(s): Groundwater flow and contamination studies
2015 - American Chemical Society | Environmental Science & Technology
Chunxia Song, Mingliang Ye, Zexian Liu, Han Cheng, Xinning Jiang, Guanghui Han, Zhou Songyang, Yexiong Tan, Hongyang Wang, Jian Ren, Yu Xue, Hanfa Zou,
... ra39Crossref PubMed Scopus (160) Google Scholar, 25Boekhorst J. van Breukelen B. Heck Jr., A. Snel B. Comparative phosphoproteomics reveals evolutionary and functional conservation of phosphorylation across eukaryotes.Genome Biol. 2008; 9: R144Crossref PubMed Scopus (65) Google Scholar). Furthermore, we combined a new multidimensional separation approach using reversed-phase-reversed-phase liquid chromatography (RP-RPLC) (22Song C. Ye M. Han G. Jiang X. Wang F. Yu Z. Chen ...
Tópico(s): Glycosylation and Glycoproteins Research
2012 - Elsevier BV | Molecular & Cellular Proteomics
Deborah Van Breukelen-van der Stoep, J. van Zeben, Boudewijn Klop, Marijke A. de Vries, N. van der Meulen, Josi Arend, Gert‐Jan van de Geijn, Hans W. Janssen, C. van Casteren-Messidoro, Erwin Birnie, Johanna M W Hazes, Manuel Castro Cabezas,
Objectives: Rheumatoid arthritis (RA) is recognized as an independent cardiovascular risk factor. Guidelines for cardiovascular risk (CVR) management, advise aggressive treatment in RA. Tight treatment for CVR factors in RA is not standard care and there are no prospective data. The aim of the study is to investigate the efficacy of CVR intervention in RA patients participating in the FRANCIS study. FRANCIS is a prospective, randomized, single centre study in RA, initiated before the guidelines advocating ...
Tópico(s): Rheumatoid Arthritis Research and Therapies
2014 - Elsevier BV | Atherosclerosis
D.F. van Breukelen-van der Stoep, Jan Zijlmans, D. van Zeben, N. van der Meulen, Boudewijn Klop, Marijke A. de Vries, Josi Arend, C. van Casteren-Messidoro, G.J.M. van de Geijn, Hans W. Janssen, Erwin Birnie, Johanna M W Hazes, Manuel Castro Cabezas,
Objectives: Patients with Rheumatoid Arthritis (RA) have an elevated cardiovascular (CV) risk. Recent guidelines suggest strict treatment of CV risk factors. Adherence to therapy, especially in the case of primary prevention, is frequently inadequate (aroud 50%). The aim of this study is to evaluate the self-reported adherence to CV prevention strategies by patients with RA participating in the FRANCIS study, a long term, randomized, single centre intervention study investigating the need for strict ...
Tópico(s): Systemic Lupus Erythematosus Research
2014 - Elsevier BV | Atherosclerosis
Kiran Altaf, Junjie Xiong, Daniel de la Iglesia, L Hickey, A Kaul, Edgar M. Wong‐Lun‐Hing, Ronald M. van Dam, Gerard van Breukelen, Pieter J. Tanis, Francesca Ratti, Richard van Hillegersberg, Gerrit D. Slooter, J. De Wilt, Kenichiro Uemura, Sohei Satoi, Fuyuhiko Motoi, Masanori Kwon, Michiaki Unno, Yoshiaki Murakami, Erik Stenberg, Éva Szabó, Johan Ottosson, Ingmar Näslund, Katsunori Imai, M.-A. Allard, Carlos Castro Benítez, Éric Vibert, A.A. Cunha, Daniel Cherqui, D. Castaing, Hideo Baba, R. Adam,
Antecedentes: El esófago de Barrett (Barrett's Oesophagus, BO) es un precursor para el desarrollo del adenocarcinoma de esófago (oesophageal adenocarcinoma, OAC).El objetivo de este estudio fue clarificar a través de un metaanálisis el papel de los biomarcadores genéticos, cromosómicos y de proliferación que han sido objeto de múltiples estudios.Métodos: Se realizó una búsqueda en las bases de datos MEDLINE, EMBASE y Cochrane Library de estudios clínicos que evaluasen el valor de p53, p16, Ki-67 y ...
2017 - Oxford University Press | British journal of surgery
Ian de Bus, Han Zuilhof, Renger F. Witkamp, Michiel G.J. Balvers, Bauke Albada,
... dryness using a speedyvac concentrator (Salm and Kipp, Breukelen, The Netherlands) and were redissolved in 100 μl ...
Tópico(s): Cannabis and Cannabinoid Research
2019 - Elsevier BV | Journal of Lipid Research
Piero Giansanti, Matthew P. Stokes, Jeffrey C. Silva, Arjen Scholten, Albert J. R. Heck,
... M.W. Mohammed S. Gouw J.W. van Breukelen B. Vos H.R. Heck A.J. Highly ... L.Y. Ding V.M. Lemeer S. van Breukelen B. Philp R. Boekhorst J. Snel B. den ... L.Y. Ding V.M. Lemeer S. van Breukelen B. Philp R. Boekhorst J. Snel B. den ... K. Wu L. Eng J.K. Rodionov V. Han D.K. Quantitative phosphoproteomic analysis of T cell ...
Tópico(s): Receptor Mechanisms and Signaling
2013 - Elsevier BV | Molecular & Cellular Proteomics
Benjamin Ruprecht, Heiner Koch, Guillaume Médard, Max Mundt, Bernhard Küster, Simone Lemeer,
... W.H. Mohammed S. Gouw J.W. van Breukelen B. Vos H.R. Heck A.J.R. ...
Tópico(s): Monoclonal and Polyclonal Antibodies Research
2014 - Elsevier BV | Molecular & Cellular Proteomics
Scott B. Ficarro, Yi Zhang, Marlene J. Carrasco-Alfonso, Brijesh K. Garg, Guillaume Adelmant, James T. Webber, Chance John Luckey, Jarrod A. Marto,
... M.W. Mohammed S. Gouw J.W. van Breukelen B. Vos H.R. Heck A.J. Highly ... 20Lemeer S. Pinkse M.W. Mohammed S. van Breukelen B. den Hertog J. Slijper M. Heck A. ...
Tópico(s): Blood disorders and treatments
2011 - Elsevier BV | Molecular & Cellular Proteomics
Sophie Verheyden, Dominique Genty, Olivier Cattani, M.R. van Breukelen,
Speleothem fluid inclusions are a potential paleo-precipitation proxy to reconstruct past rainwater isotopic composition (δ18O, δD). To get a better insight in the extraction of inclusion water from heated speleothem calcite, we monitored the water released from crushed and uncrushed speleothem calcite, heated to 900 °C at a rate of 300 °C/h, with a quadrupole mass spectrometer. Crushed calcite released water in three not well individualised peaks between 25 and 360 °C, 360 and 650 °C and between 650 ...
Tópico(s): Karst Systems and Hydrogeology
2007 - Elsevier BV | Chemical Geology
R. A. Nelson, Wahner Hw, J. D. Jones, Ellefson Rd, Zollman Pe,
... Molecular Aspects of Metabolic Plasticity in MammalsFrank van Breukelen and Sandra L. Martin1 July 2015 | Physiology, Vol. ...
Tópico(s): Meat and Animal Product Quality
1973 - American Physiological Society | American Journal of Physiology-Legacy Content