Richard Harries, Chairman, Arthur Leathley, Transport Correspondent, R. Kristiansen, Ken Hughes, Nick Nuttall Environment Correspondent, Robert Cole, Michael Aylwin, Catherine Riley, Andrew Pierce, Olu Abiola, Chairman, Stephen Farrell and Arthur Leathley, Transport Correspondent, Rob Hughes, Simon Barnes, Alison ELLIOTCovernor, Julian Lee, Paul Hoggart, Claire McDonald, Bernard Kaukas, Frances Gibb, Legal Editor, Reports from the Bar Conference, Michael Evans Defence Editor, Philip Howard, Hilary Finch, Steve Branley, Norman De Mesquita, Mark Benham and Adam Sherwin, Uri Geller, Michael Paterson, Carla Quirighetti, James Landale, Political Correspondent, Michael Evans, Defence Editor, Eduard Fuller, David Robinson and Perry Cleveland-Peck, Tony Patrick, Stewart Tendler, Crime Correspondent, Jorge Elias, Tim Rodber, Fraser Nelson, Retail Correspondent, Robert Sheehan, Bridge Correspondent, Ernest A. Hounsell, Mark Benham, Pat Gibson, David McVay, Ruth Gledhill, Religion Correspondent, Nick Martin, Donald Hutera, Ruth Gledhill, Shirley English, John O'leary, Education Editor, Alasdair Reid, Michael Forrest, Raymond Keene Chess Correspondent, Keith Dugdale, Ross Dunn, Audrey Magee Ireland Correspondent, Rita Carter, Alan Hamilton, Robin Young, Mark Inglefield, Rodney Milnes, Alice Lagnado, Frederick Hutchinson, Tony Blair, James Landale Political Correspondent, Helen Rumbelow Medical Reporter, Ian Hughes, Keith Pike, Alix Ramsay, Tennis Correspondent, David Hands, Jean Glavany, Mark Giles, Gerald CORBETTChief Exeutive, Rodney Mlines, Lisa Armstrong Fashion Editor, Peter Barnard, Michael Howard, Christopher Pinsent, Paula Hawkins, Russell Kempson, Paul Durman, David Lister, Nicholas Harling, John Hopkins, Arthur Leathley and Clive Mathieson, Rob Wright, Stephen Wood, David Watts, Stuart Miles, Adam Jones, Raymond Keene, Adam Sage, Clive Mathieson, Matthew Pryor, Richardson of Calow Moderator, Matt Dickinson, Alison Kervin Rugby Editor, David Coffey, General Secretary, Oliver Holt, Richard Owen, Damian Whitworth, Jeremy Fletcher, Mick Hume, Roger Boyes, Nigel Hawkes, Science Editor, Martin Woods, Paul Fitzapatrick, Nick Hasell, Sydney Friskin and Cathy Harris, Oliver Holt, Football Correspondent, Christopher Massey, David Hands Rugby Correspondent, Roger Bootle, Jennifer O'Neill, Nick Szczepanik, John Goodbody, Simon Munk, Alan Copps, Alex O'Connell, Mel Webb, Witold Gutt, Kevin McCarra, Jennai Cox, Sean Hargrave, George Caulkin, Chris McGrath, Tim Wapshott, Walter Gammie, Peter Riddell, Oliver Chastney, Ray Hatley, Ian Brodie, Edward Karam, Tony Dawe, Michael Dynes, Fraser Nelson, Lea Paterson, Mark Henderson, Chris Ayres, Mark Baldwin, Roger Rowberry, Benedict Nightingale, Peter Smith Chairman, Nigel Powell, John B. Sheldon, Stephen Dalton, Bill Edgar, Valerie Grove, Adam Sherwin, Alex O'connell, Carl Mortished and David Lister, Richard Ford, John Bennett, Christopher Irvine, Christine Buckley, Industrial Correspondent,
... entertaining Sonic's bright new world Saga's hedgehog hits a new level, says Tim ... What is a Games Engine? Cutting edge of graphics Down in the Valley, ...
1999 - Gale Group | TDA
Evelyne Lima‐Fernandes, Alex Murison, Tiago da Silva Medina, Yadong Wang, Anqi Ma, Cherry Leung, Genna M. Luciani, Jennifer Haynes, Aaron Pollett, Constanze Zeller, Shili Duan, Antonija Kreso, Dalia Baršytė-Lovejoy, Bradly G. Wouters, Jian Jin, Daniel D. De Carvalho, Mathieu Lupien, C.H. Arrowsmith, Catherine O’Brien,
Abstract In embryonic stem cells, promoters of key lineage-specific differentiation genes are found in a bivalent state, having both activating H3K4me3 and repressive H3K27me3 histone marks, making them poised for transcription upon loss of H3K27me3. Whether cancer-initiating cells (C-ICs) have similar epigenetic mechanisms that prevent lineage commitment is unknown. Here we show that colorectal C-ICs (CC-ICs) are maintained in a stem-like state through a bivalent epigenetic mechanism. Disruption ...
Tópico(s): Genomics and Chromatin Dynamics
2019 - Nature Portfolio | Nature Communications
Bernard Merivale, James Parish, Virginia Cherrill, J. M. Scott, P. H. A. Scott, Mary Herbert, Doreen Wallace, James Agate, Mark Hambourg, E. L., Katherine M. Buck, Eiluned Lewis, Eleanor Graham, Bernard J. King, B. M., Hungarian, Francis Deverell, J. Landfear Lucas, Sir F. G. Hopkins, St. Andrew's, John Brophy, Hamilton Price, J. Wentworth Day, Col. De La Rocque, Mr. M. J. Savage, Mr. Morrison, H. M. Abrahams, King George, Evan W. H. Fyers (Major), H. A. Spowart, A. T. Johnson, G. W. B., L. Bus-Fekete, F. R. H., Hugh de Selincourt, J. J. R., Frank Rutter, Milward Kennedy, S. Vatcher, H. E. Vallentin (Lieut.-Col), R. A. L. Hartman, D. R. Gent, Llewelyn Powys, J. M. Fleming, Desmond MacCARTHY, Derek Patmore, H. F., Basil Tozer, Jowett, Sir Edgar Britten, A. H. N., "Autolycus", E. B. Maunsell (Colonel), Rowan Boone, Ernest Newman, Mr. MacDONALD, A. Ernest Whtting, J. E. Forrest, Georgiana Curzon's, Ralph Straus, E. V. Lucas, Mr. J. Whitehead, E. V. Lucas., R. Bruce Lockhart, Muriel Beckwith, Sydney W. Carroll, Sir Eric Geddes, C. H. P. Lamond, Victoria Hopper, Edward Shanks, Dilys Powell, Oscar Teichman, H. E. Symons, Crown Prince, J. Paton, Elmer Rice, R. J. Barrett Financial Editor, Ashley Sampson, Sir Arthur Keith, Hubert J. Norman, F. R. Ridley, Henry Longhurst, A. Brooker, E. N., A. R. Cripps, Yarborough, Horace Shipp, L. A. G. Strong, J. M. Bulloch, P. Hann, George W. Bishop, David Hunter Blair, S. E. Winbolt, Sarah Gertrude Millin, Sir John Squire,
... 2s.) For ages 4-6 Adventures of Horace Hedgehog. By P. B. and E. C. Ardley. (Collins. ...
1935 - Gale Group | Sunday Times HA GDA
Margarita E. Carrasco, Roman Thaler, Gino Nardocci, Amel Dudakovic, André J. van Wijnen,
Bivalent epigenomic regulatory domains containing both activating histone 3 lysine 4 (H3K4me3) and repressive lysine 27 (H3K27me3) trimethylation are associated with key developmental genes. These bivalent domains repress transcription in the absence of differentiation signals but maintain regulatory genes in a poised state to allow for timely activation. Previous studies demonstrated that enhancer of zeste homolog 2 (Ezh2), a histone 3 lysine 27 (H3K27) methyltransferase, suppresses osteogenic differentiation ...
Tópico(s): Genomics and Chromatin Dynamics
2023 - Elsevier BV | Journal of Biological Chemistry
FROM OUR RACING CORRESPONDENT, FROM OUR NEWMARKET CORRESPONDENT, FROM OUR SPECIAL CORRESPONDENT, FROM OUR BILLIARDS CORRESPONDENT, FROM OUR GOLF CORRESPONDENT, FROM OUR BISLEY CORRESPONDENT, Professor Norman Bentwich, A correspondent, GEORGE SHEE., PAIGE ARNOLD, GUARDIAN., EDWARD PERCY, HESKETH BELL., COSMO CANTUAR:, P. E. MITCHELL (Governor of Uganda), CYRIL UGANDA, LUGARD., FROM OUR CORRESPONDENT, FROM OUR OWN CORRESPONDENT, By CALLISTHENES, From Our Special Correspondent, FROM OUR LEAGUE CORRESPONDENT, From Our Correspondent, FROM OUR NAVAL CORRESPONDENT, From Our Own Correspondent, FROM OUR DIPLOMATIC CORRESPONDENT, From Our Parliamentary Correspondent, From Our Aeronautical Correspondent, CECIL HARMSWORTH., E. G. SELWYN., J. M. KEYNES., FRANK FLETCHER., B. H. STREETER, KENNETH M. CHANCE., P. S. SPOKES, F. A. BEARN, From Our Riga Correspondent, FROM A CORRESPONDENT, FROM OUR MONTEVIDEO CORRESPONDENT,
... Time For Apathy Severance Of Trade Relations, A Hedgehog On The Hearth, The Voluntary Hospitals Recruits For ...
1937 - Gale Group | TDA
Christine L. Chaffer, Nemanja D. Marjanovic, Tong Lee, George W. Bell, Celina G. Kleer, Ferenc Reinhardt, Ana C. D’Alessio, Richard A. Young, Robert A. Weinberg,
The recent discovery that normal and neoplastic epithelial cells re-enter the stem cell state raised the intriguing possibility that the aggressiveness of carcinomas derives not from their existing content of cancer stem cells (CSCs) but from their proclivity to generate new CSCs from non-CSC populations. Here, we demonstrate that non-CSCs of human basal breast cancers are plastic cell populations that readily switch from a non-CSC to CSC state. The observed cell plasticity is dependent on ZEB1, ...
Tópico(s): Cancer Genomics and Diagnostics
2013 - Cell Press | Cell
Jonathan Swift, L. J. Corbett, Kenneth M. King, J. J. R. Trethowan, E. Colston Shepherd The Sunday Times Air Correspondent, Katharine Monkswell, Monsignor R. A. Knox, (Rev.) Arthur Morton Director, Stephen Coulter Representative of The Sunday Times, Elizabeth Nicholas, Francis Iles, Harold Hobson, Eoin O'Keeffe, Victor West Secretary, Allan Chappelow, Basil Dean, Kenneth Pearson, O. G. W. Stallybrass, Nicholas Carroll The Sunday Times Diplomatic Correspondent, Elleen Griffin, E. M. C., R. C. Johnston, J. D. Moody, Cyril Beaumont, L. Scottish, John Culmer The Sunday Times Representative, H. D. F. Kitto, John Russell, Elizabeth David, Mary Dunbar, C. M. Grosett, Vivian Jenkins, Marie Scott-James, Iain Lang Foreign Editor of The Sunday Times, Theo. A. Stephens, K. P., Antony Terry The Sunday Times Representative, F. A., Cyril Connolly, Ian Fleming, E. M. Gordon, M. S-J., Rose MaCaulay, Charles E. Gayton The Sunday Times Political Correspondent, Raymond Mortimer, W. Mayo, Alan Chalkley The Sunday Times Representative, Arthur Mizener, Ernest Newman, J. B. Slade-Baker The Sunday Times Special Representative, Henry Brandon Representative of The Sunday Times, Susan Noel, Betty Miller, Roger Mortimer, Norman Crump The Sunday Times City Editor, Ernestine Carter, Michael Hadley, Alan McGregor The Sunday Times Representative, Alken McClelland, John Hayes Assistant Keeper, R. L. Hollands, Patrick Leigh Fermor, Joseph Mostyn The Sunday Times Representative, Colonel G. A. Tokaev In an exclusive Question and Answer interview with The Sunday Times, Terence Lyons The Sunday Times Representative, Harold Abrahams, Felix Aprahamian, Maurice Cranston, Michael Sadleir, Robert Robinson, Henry Longhurst, V. W. Garratt, Godfrey Smith, Iain Lang, C. H. O'd. Alexander, George Schwartz, Maurice Wiggin, Atticus, Jacquetta Hawkes, (Rev.) W. J. S. Weir, Kenneth Konstam, Lady Diana Cooper, H. E. Bates,
... Editor Cruelty to Children Marriage and Divorce The Hedgehog Literary Spans Associated Electrical Industries Ltd. Scotch Boats ...
1956 - Gale Group | Sunday Times HA GDA
Eiki Koyama, Christina Mundy, Cheri Saunders, Juliet Chung, Sarah E. Catheline, Danielle Rux, Masahiro Iwamoto, Maurizio Pacifici,
ABSTRACT The growth plates are key engines of skeletal development and growth and contain a top reserve zone followed by maturation zones of proliferating, prehypertrophic, and hypertrophic/mineralizing chondrocytes. Trauma or drug treatment of certain disorders can derange the growth plates and cause accelerated maturation and premature closure, one example being anti-hedgehog drugs such as LDE225 (Sonidegib) used against pediatric brain malignancies. Here we tested whether such acceleration and closure in LDE225-treated mice ...
Tópico(s): Epigenetics and DNA Methylation
2020 - Oxford University Press | Journal of Bone and Mineral Research
Giles Smith, Andrew Robson, Gabriele Marcotti, Jonathan Kearney, Raymond Snoddy Media Editor, Ranulph Fiennes and Mike Stround, Thair Shaikh, Catherine Riley, Andrew Pierce, DJM, Grace Bradberry, Adam Sherwin Media Reporter, Frances Gibb Legal Editor, Peter Lansley, Laurie Arle, Paul Hoggart, Mark Souster, William Cumber, Richard Hobson, Lisa Melton, Michael Evans Defence Editor, Philip Howard, Hilary Finch, Jennal Cox Fitness Editor, David Chater, James Bone, James Ducker, Carl Mortished, Dominique Searle, Patrick Barkham, Paul Nicolson, Martin Drent, David Mattin and Jonathan Richards, David Sharrock, Martin Fletcher, Ben Webster Transport Correspondent, Pat Gibson, Valerie Elliott Countryside Editor, David McVay, James Gaussen, Nigel Israel, Dominic Walsh, James Doran Wall Street Correspondent, Debra Craine, Gary Jacob, Jill Dupleix, Phoebe Greenwood, Richard Ford Home Correspondent, Robin Young, Stephen Farrell, Douglas Brewer, Phil Gordon, Roland Watson, Keith Pike, David Hands, Roland Watson, James Hider and Richard Beeston, David Charter, Nicholas Wapshott, Norman Giller, Raj Kothari, Ben Heap, Ronan McGreevy, Bryan Cassidy, Michael Theodoulou, Rick Broadbent, John Hopkins, Gabriella Gamini, Elaine Monaghan, John Muir, Neil Harman Tennis Correspondent, David Powell Athletics Correspondent, Marcus Binney, Raymond Keene, Ian Evans, Christine Buckley, Jane Cambridge, Matthew Pryor, Christine Buckley Industrial Editor, Nick McIVER, Nigel Hawkes, Ronan McGreevy and Laura Peek, Burhan Wazir, Michael 'Ned' Kelly, Russell Hotten, Cathy Harris, David Hands and Owen Slot, Mick Hume, Clem Cecil, Emily Davies, Jon Ashworth and Glen Owen, Peter Dixon, David Hands Rugby Correspondent, Owen Slot Chief Sports Reporter, Tony Cascarino, Julian Muscat, Paul Simons, Paul Chesters, Tom Dart, Earl Beal, Michael Bor, William Rees-Mogg, Nell Harman Tennis Correspondent, Nick Szczepanik, John Goodbody, Giles Whittell, Melissa Kite Political Correspondent, Christopher Walker, Robert Maxwell, Peter Lansely, Jane Shilling, Tim Hames, Ian Johns, Michael Wilson, Mike Rosewell, Sam Allardyce, Robert Richardson, Michael Austin, Iain Catto, Walter Gammie, David McVAY, Ian Forsyth, Richard Beeston, Brian Clarke, David Charter Chief Political Correspondent, Lea Peterson, David Sinclair, Lea Paterson, Lewis Stuart, Gary Duncan Economics Correspondent, Martin Waller, Chris Ayres, James Jackson, David Charter and Christine Buckley, Nigel Hawkes Health Editor, Sarah Butler, Ashling O'Connor, Lenny Henry, Stephen Dalton, Dr Thomas Stuttaford, Stephen Gardiner, Ben Hoyle, Leo Lewis, Richard Morrison, Bill Edgar, Alyson Rudd, James Christopher, Paul Connolly, Courtenay Griffiths, Linda Dobbs, Oba Nsugbe, Mark Venables, Matthew Connolly, John Phillips, Alan Lee Racing Correspondent, Owen Slot, Edward Gorman Sailing Correspondent, Christopher Irvine,
... Life Expectancy Will Plummet to that of a Hedgehog Crossing the M25, Says Paul Hoggart TV Review ...
2003 - Gale Group | TDA
... Good to Great, to help organizations identify a hedgehog concept, or primary reason for their existence: (1) What are we deeply passionate about? (2) What can we be the best in the world at? and/or What can we not be the best in the world at? (3) What drives our resource engine? By drawing on ideas from physical education scholars to answer these questions, this article shows that providing a large quantity of quality opportunities for students to learn to play is a legitimate hedgehog concept for physical education.
Tópico(s): Children's Physical and Motor Development
2014 - Taylor & Francis | Journal of Physical Education Recreation & Dance
John Huxley, Thomas Keneally, John Shirley, Stephen Dodgson, Paul Theroux, Charles Raw, Steve Jones, John Forsyth, Bel Mooney, Jon Swain, Peter Gillman, Athole Still, John Peter, Chris Tighe, Kenneth Allsop, Nick Gilbert Deputy City Editor, Peter Calvocoressi, Berry Ritchie, Graham Rose, J. W. Lambert, Barry Foster, David Beake, Robin Morgan, John Whale Religious Affairs Correspondent, Dalbert Hallenstein, Jason Tomas, Henry Porter, Jancis Robinson, Philip Oakes, John Lawless, Raymond Williams professor, John Coates, Rosemary Fox Honorary Secretary, John Veltom farmer, J. S. P. Roberton, Mick Brown, Deryk Brown, Keith Botsford, Robin Wright, David Dougill, Misha Do. . ., Joe Irving, Stanley Sadie, Nicholas Shrimpton, David Puttnam, Brian Montgomery, Nigel Hawthorne, Jon Wynne-Tyson Writer, Ken Russell, David Cairns, Peter Kerrigan, David Rossall, Norman Harris, Donald Macintyre Labour Editor, David Blundy, Donald Macintyre, Jon Connell, Giles Merritt, Geoff Whitten, St Ethelwold, Peter Ackroyd, Lionel Barber, Geoffrey Cannon, Robin Marlar, Bob Marley, Tony Willard, John Bromley, John Sheppard, mullahs, Brian Moynahan, G S Whittet, Patrick Forman, John Keegan, Roger Eglin, Ann Boyd, Kenneth Austen prisoner, Woodrow Wyatt, Tana de Zulueta, Peter Shearlock, Sean French, Michael Croft Director, George Rosie, David Hughes, Claire Tomalin, Anthony Storr, Kathy Robinson Teacher and writer, Nick Gilbert, John Hopkins, Brian Sewell, David Lipsey Economics Editor, John Barry, John Barnes, Jill Neville, Eric Marsden, John Whitley, Don McPherson, Hugo Young Political Editor, Bryan Silcock, Simon Freeman, Jack Berry, Gareth Huw Davies, Philip Pilling, Malcolm Winton, Hannah Charlton, Elaine Potter, Simon Frith, Stephen Jones, Hirsh Goodman, Desmond Shawe-Taylor, Tony Levene, Roger Bolton, Russell Davies, Michael Wood, David Welch, Martin Kettle, V. S. Naipaul, Kathy J. Moores Mother, David Lodge, David Lipsey, Chris Salewicz, Pete Townshend, Brough Scott, Bill Cater, Gavin Millar, Plus Raymond, Geoffrey Palmer, Oliver Gillie Medical Correspondent, Tony Osman, Zandra Rhodes, Kim Fletcher, Dr Margaret Maison, Dudley Doust, Felix Aprahamian, Philip Kleinman, Peter Wilby, Gitta Sereny, Rosmary Righter, Lewis Chester, Peter Shearlock City Editor, Mihir Bose, Angela Neustatter, Peter Clarke, Godfrey Smith, Suzanne Lowry, Brian Glanville, John Carey, Georgina Howell, Cindy Polemis, James Fenton, Michael Green, Nicholas Shakespeare, Will Elsworth-Jones, Charles Gans, Michael Jones Political Correspondent, Douglas Bell, Marina Vaizey, Amir Taheri, Phillip Knightley, Roy Foster, Philip Jacobson, Nicholas Kenyon, Harry Coen, Patience Wheatcroft, Joan Smith, Leslie Geddes-Brown, Isabel Hilton, Boris Schapiro, Gordon P Getty,
... Second David Welch Council Officer Take one diced hedgehog and a cup of warm water The sky ...
1983 - Gale Group | Sunday Times HA GDA
Sung-Won Jin, Ki-Bum Sim, Sang-Dae Kim,
Understanding the development of a skull deformity requires an understanding of the normal morphogenesis of the cranium. Craniosynostosis is the premature, pathologic ossification of one or more cranial sutures leading to skull deformities. A review of the English medical literature using textbooks and standard search engines was performed to gather information about the prenatal development and growth of the cranial vault of the neurocranium. A process of morphogenic sequencing begins during prenatal ...
Tópico(s):
2016 - Korean Neurosurgical Society | Journal of Korean Neurosurgical Society
Malcolm Harper, Director, Andrew Ailes, Victoria McKee, Anthony Harris, Tunku Varadarajan, Gerald Isaaman, Paul Heiney, Le Gallois, Andrew Pierce, Ronald Geddes, Rob Hughes, Anthony J. Roberts, Simon Barnes, Rob Hughes, football correspondent, Jan Morris, Alexandra Frean, Media Correspondent, Gabriella Gamini, South America Correspondent, Janet Bush, Economics Correspondent, Harvey Elliott, John Diamond, Walkman, Donald Foreman, Secretary, T. V., Philip Howard, Matthew D'Ancona, Eric Mawer, Michael Binyon, George Sivell, Jane Laldlaw, Michael Chichester, P. Popplewell, Chief Rent Officer, Carl Mortished, Srikumar Sen, Diane Modahl, Morag Preston, Kevin Eason, J. St Clair, Stuart Jones Tennis Correspondent, Geoff Brown, Jeremy Seal, Ian Pratt, Robert Miller, Martin Fletcher, Mary Keenan, Secretary, Donald C. Flatt, Robert Sheehan, Dayanita Singh, Bernard Beatty, (Academic Editor), Robson Green, Ruth Gledhill, Jo Cutmore, Debra Craine, Alice Thomson Political Reporter, John McLeod, Richard Evans, Racing Correspondent, Thomas De Waal, Lucy Partington, Alan Hamilton, John Stidolph, Timothy Rice, Michael Clark, Jeremy Laurance, Health Correspondent, Barry Overend, Denis Christian, Doug Sager, Frances Bissell, David Hands, Anna Blundy, Peter Cleveland-Peck, Sarah Bagnall, Belinda Harley, Peter Barnard, David Charter, Ros Drinkwater, Derwent May, Gerald Kaufman, Justin Cartwright, Graham Wood, Lizanne Rose, Russell Kempson, Richard Cork, Jessica Gorst-Williams, Stephen Anderton, Jayne Lynds, Lenny Kravitz, Michael Munro, Helen Chislett, Adam Sage and Stewart Tendler, Crime Correspondent, Matthew Perry, Gabriella Gamini, Jill Insley, Andy Thompson, Mitch Jenkins, George Plumptre, Gillian Bowditch, Scotland Correspondent, Raymond Keene, Vaughan Freeman, Christine Buckley, David Robinson, Nicole Daniels, Jonathan Prynn Transport Correspondent, Emma Wilkins, Alistair McIntosh, James Bartholomew, Peter Capelia, Jenny McClean, Paul Wilkinson, P. H. S, Clare Riley, Stephanie Lewis, M. C. Fitzpatrick, Richard Evans, Michael Arditti, Joan O. E. Atkins, Roger Boyes, Nigel Hawkes, Science Editor, Oliver August, Hugh Johnson, Julian Muscat, Christopher Thomas, Anne Ashworth, John Goodbody, Jane Bidder, Sara McConnell, Alan Copps, Christopher Walker, James Pringle, Robert Crampton, S. A., Desmond Heap, Julie Andrews, Janet Mattacks, Tim Wapshott, V. Dyer, Helen Mound, Jane Owen, Robert Boyd, Ben MacIntyre, Helen Pridham, Graham Lord, Richard Beeston, David Sinclair, Simon Jenkins, Kate Bassett, Michael Horsnell, Gillian Bowditch and Magnus Linklater, Lisa Verrico, Jill Parkin, Caroline Owens, Arthur Leathley and James Landale, Tom Rhodes, Marianne Curphey, Jill Sherman, Political Correspondent, Hugh Thompson, Jill Crawshaw, John Stanier (Constable), Michael Evans Defence Correspondent, Jonathan Meades, Bill Frost and Richard Duce, Richard Morrison, David Powell, Elizabeth Buchan, D. J. Riddett, Michael Henderson, Anne McElvoy, Mark Wallinger, James Gilbey, John Phillips, Alasdair Murray, Penny Perrick, Derek R. W. Wood, Dr Dashboard, David Hands, Rugby Correspondent, William Mellor, Christopher Irvine, Ed Harris, Michael Argyle, Melvyn Marckus,
... farm Farmer's Diary How to save a hedgehog on Guy Fawkes Night Hedgehogs are known to ... when Christopher Thomas rides on the footplate of Engine 2233 he finds no one to lament its ...
1995 - Gale Group | TDA
Samara Ginzburg, Joanne M. Willey, Carole Lynne Bates, Sally A. Santen, David Battinelli, Lawrence Smith,
... framework designed to transform companies—to UME. The hedgehog concept is defined by the intersection of an organization’s passion, area of expertise, and economic and resource engines. Focusing on this single concept can guide key decisions, reject what does not align conceptually, and drive overall organizational success. The authors use the hedgehog concept to frame the programmatic development of the ... systems-based care; and the economic and resource engine of faculty time, financial and infrastructure support, and reputation building. The success of this approach is assessed at Zucker SOM through student and graduate outcomes data. The authors suggest that this hedgehog concept is generalizable to other UME programs whose ...
Tópico(s): Empathy and Medical Education
2019 - Lippincott Williams & Wilkins | Academic Medicine
Susan D'arcy, Michael Prescott, Julia Pascal, Barbara Hall, Annie Chaplin, Toby Young, Tony Birtley, Paul Nelson, Richard Ellis, Seosamh O Murchú, John Davison, Peter Frank, Helen Davidson, Debbie Moore, diana Wright, John Peter, Mark Reason, John Harlow Transport Correspondent, Jonathan Miller, Eric Dymock, Norman MacRae, Lesley White, Dr Mary Henry, Bill Gates, Tony Francis, Susan d'Arcy, John Akers, John Diamond, Graham Rose, Diana Wright Personal Finance Editor, Alistair Scott, Sally Payne, David Smith, Nicholas Hinton Director-general, Adam Nicolson, Nick Pitt, Taylor, Frederic Raphael, Charles Hymas, Edward Welsh, Richard Guilliatt, Caroline Lees Arts Correspondent, Tony Allen-Mills, Martin James, Robert Sandall, Joanne Harris, Benedic Hayhoe, Ivan Allen Exhibition Director, Iain Johnstone, Nilgin Yusuf, Irwin Stelzer, Ivan Fallon, Deryk Brown, Isabel Wolff, David Dougill, Cliff Temple, Ally McCoist, Ingrid Millar, Harvey Porlock, Hugh Canning, Margarette Driscoll, Peter Kemp, Sean Ryan, Geoff Whitten, Peter Millar, Caroline Lees, Ismail Merchant, Peter Kellner, Richard Dawood, George Perry, John Cassidy, Kristle Hamilton, Mark Skipworth, Anatole Kaletsky, Nick Gardner, Lynne Routledge, Stewart Roberts, Jonathan Margolis, Christine Toomey, Richard Lloyd Parry, Bernard Cafferty, David Bowie, Stuart Wavell, Roger Eglin, Paul Donovan, Paul Eastman, Christopher Llyod, Jeff Randall, Shelley von Strunkel, James Bethell, R Nicholson-Morton, James Adams, Paul Driver, Margaret Dibben, Charlie Bubbles, Nicholas Fraser, Tim Rayment, Peter Plant, Kirstie Hamilton, Rufus Olins, David Lawrenson, Brian Sewell, Martin Jacques, Nicola Lang, Dave Thomas, Christopher Lloyd, Derek Hudson, Helen Fielding, kristie Hamilton, Lois Rogers, Margaret Campbell, John Karter, Jack Aspinall, Malcolm Winton, Peter Hall, Greg Hadfield, Diana Wright, Craig Brown, Stephen Jones, Imogen Edwards-Jones, Andrew Grice Chief Political Correspondent, Quentin Crisp, Andrew Grice, Irwin Steizer, Julie Cohen, Keith Wheatley, Annie Murphy, Ian Birrell, Anthony Quinn, Marcel Berlins, Safa Haeri, Lois Rogers Medical Correspondent, Chris Jones, Andrew Hogg, Bruce Johnston, R Scheer, T Rac Smith, Richard Woods, Garth Alexander, Paul Kennedy, Peter Johnson, David Churchill, Alan Dershowitz, Maurice Chittenden, Sarah-Rhiannon Barber, N E Gayle, Dr Richard Sakwa, David Oates, Kristie Hamilton, Dai Jeffries, Julie Burchill, David, Michael Jones Political Editor, Roger Clarke, Rebecca Fowler, Nicholas Archer, David Hunn, John Bowman, Berry Tomalin Head of Marketing, D J Taylor, Mihir Bose, John Harlow, Matthew Lynn, Michael Austin, Hugh Fearnley-Whittingstall, Andrew Alderson, Alastair Burnet, Matthew Campbell, Stan Levenson, John Carey, Brian Innes, Christopher Summerfield, Chrissy Iley, Robert Leyshon, Lauren St John, Tom Tickell, Gilbert Adair, John Furbisher, Liam Clarke, David Wickers, Alan Ruddock, Goliath, Victor Bryant, Chris Lightbown, Mia Farrow, Nigel Roebuck, Jeff Randall City Editor, Hugh Pearman, David Smith Economics Editor, Penny Perrick, Tony Hetherington, Walter Ellis, Joanna Simon, kirstie Hamilton, Iain Jenkins, Janine di Giovanni, Boris Schapiro,
... their former hero, asks Alan Ruddock Sonic the Hedgehog Stogecoach Holdings plc Swansea Centre for Trade & Industry ... bonus schemes the best thing since the jet engine, writes David Wickers Gateways to Uncle Sam's ...
1993 - Gale Group | Sunday Times HA GDA
... are 96 "popular" FAQ indexes covering everything from hedgehogs to the Bee Gees. A search engine directs visitors to an even larger group of ...
Tópico(s): Environmental DNA in Biodiversity Studies
2010 - Future Science Ltd | BioTechniques
Tijuca Rio de Janeiro, Taki, Tara Palmer-Tomkinson's, Waldemar Januszczak, John Dugdale, Michael Prescott, Victoria McKee, Christopher Middleton, Barney Spender, Barbara Hall, Aa Gill, Royal Ballet, Donald MacGillivray, Michelene Wandor, Ellie Giles, Lewis Reed, John Peter, Emma Moore, Surf bikinis, Anthony Edwards, Alicia Wyllie Deputy Money Editor, Lesley White, John Jay, Christopher Somerville, Phillip Taylor, Emine Saner, Monica Crowley, Ivo Tennant, Abbey, Ferdinand Mount, Addison de Witt, S C Peterborough, Dr C Cole, Allan Brown, Lars Persson, David Smith, Ed Wallis's, David Eden, Edin Hamzic, Sally Payne, Chris Dignan, Nick Pitt, Donu Kogbara, Neil Wormald, E Warmington, Andrew Sullivan, Ruport stolner, Clive Davis, Vincent Kearney, Carol Sarler, Mary Wilson, Karen Robinson, K R, Dr Roger Henderson, Ivo Pogorelich, Andrew Grice Political Editor, Thrasy Petropolous, Peter Wardley, Tony Allen-Mills, Simon Wilde, Martin James, Robert Sandall, Eleanor Mills, Anthony Sattin, Steve Farrar, Andrew Nebel Director of Marketing, Robert Hewison, Peter Wilson, Roger Anderson, Angela Mollard, Philip Flaxton, Lucas Black, Norman Davies, Ann Widdecombe, Darcey Bussell, Philip Kingsley, L P, Damon Hill, Bill Hagerty, Sarah Toyne, David Hewson, Harvey Porlock, Yvonne Ridley, Margaret Coles, Hugh Canning, David Caims, Jeremy Clarkson, Peter Kemp, Edward Porter, Stewart Lee, John Waples Deputy City Editor, Michael Jones, Ms L B Peterborough, George Perry, Robin Marlar, Graham Otway, Hugh McManners Defence Correspondent, Nick Gardner, Shelley von Strunckel, Cl-P, A Francis, Naomi Campbell, Paul Ham, Stuart Wavell, Maggie Gee, Paul Donovan, William Shawcross, Veronica Masters, Sue Lawrence, Justin Cartwright, Sandra Kasalo, Stan Labovitch, Paul Driver, Derek Clements, L G, Peter Windsor, Ian Hawkey, Ian Chadband, Alex Ferguson, Christopher Morgan, Alicia Wyllie, Dr Tom Parry, John Ashelford Director, Michael Prescott Chief Political Correspondent, Tom Shone, Mark Edwards, Sarah Gracie, Susan Clark, Fiona McHugh, Mark Austin, Jack Epstein, Hugh McLlvanney, Nicholas Rufford Home Affairs Editor, Malcolm Gloak, Edward Crabtree, Phil Baker, Michael Riding, John Harlow Arts Correspondent, Hugo Barnacle, Lois Rogers, Bob Graham, Raymond Keene, John Karter, Stanley Stewart, Cosmo Landesman, Peter Davison, Andrew Roberts, Andrew Butcher, Tony Fernandes, Debbie Hill, Diana Wright, Andrew Ritchie, M Carmichael, Simon Willis, Nicholas Tucker, Chris Partridge, Stephen Jones, Richard Evans, Nick Cain, Fiery Donald, M Lowe, Natalie Graham, Andrew Smith, Paul Nuki, David Pleat, Pere Ubu, Amenda Ursell, Keith Wheatley, Claire Oldfield, David Walsh, Caroline Gascoigne, John Stern, Trevor Lewis, Jack Grimston, Ruport Steiner, Barry Simms, Rasselas, S F G, Stephen Armstrong, Christopher Goodwin, John Carlos, Paul Kavanagh, Josh Salzmann, R W Johnson, Sheryl Garratt, Diana, Roland White, Miss Jean Brodie, Dr John Hemming, Chatterley, Ruport Stolner, Rachel Cooke, John Travolta, Maurice Chittenden, Kevin Pratt, Andrew Lorenz Business Editor, Kevin Donovan, Judith O'Reilly, Ray Hutton, John Wilcockson, Jon Ungoed-Thomas, Andrew Rogers, Peter Watts, Susan Elkin, George Orwell, Michael Sheridan, Redgrave Crew, Sean Hargrave, Fay Weldon, David Starkey, John Harlow, Christine Webb, Matthew Lynn, Godfrey Smith, Ted Hughes, Ian Thomson, Bob Davis, Nia Williams, Mary Chalaye, J A, Andrew Alderson, John Waples, Gareth Jenkins, Roy Hattersley, A A Gill, Jeremy Hart, Andrew Stephen, Matthew Campbell, Lloyd Webber, John Carey, David Hutcheon, Rajeev Syal, Neil Hamilton, Nadine Meisner, Robert Johnston, Jim Clark, Stephen Pettitt, Trushar Barot, Cherry Norton, Robert Prior, Andrew Lorenz, Liam Clarke, David Wickers, Emily Jewsbury, Mark Hodson, Mary Henderson, Ray Perry, Rupert Steiner, Ali Stewart, Chris Lightbown, Lucy Broadbent, Hugh Pearman, Dave Selby, David Parsley, John Phillips, John Burns, David Smith Economics Editor, J R, Simon Trump, Zoe Linkson, Richard Nixon, Jonathan Aitken, Frank Taylor, Carey Scott, Stephen Boyd, Joanna Simon, Simon Howard, Dan Pearson, Dominic Rushe, Boris Schapiro, Adam Parsons,
... flag Saab Cambridge honours its forgotten women Sonic hedgehog alarm keeps death off roads Teletubby creator to ... online version for the speed of its search engine Robots bid for World Cup glory Automation Copier ...
1998 - Gale Group | Sunday Times HA GDA
George Virich, V. Gudi, Alessandra Canal,
Extramammary Paget's disease (EMPD) is a rare intraepithelial adenocarcinoma, affecting mainly 50–70-year-olds with a female preponderance of 3:1. Exposure to polyaromatic hydrocarbons (PAHs) is associated with a substantial risk of skin cancer. We report a case of 64-year-old male with longstanding occupational exposure to used engine oil presenting with EMPD of the left scrotum and groin.
Tópico(s):
2007 - Elsevier BV | Journal of Plastic Reconstructive & Aesthetic Surgery
By Hugh Noyes Parliamentary Correspondent, From Hugh Mabbett, By Our Labour Staff, By Maurice Corina Industrial Editor, From Michael Knipe, By John Young Planning Reporter, By Peter Evans and Marcel Berlius, By Penny Symon Political Staff, From Our Correspondent, By Our Home Affairs Correspondent, By Arthur Reed Air Correspondent, From Stewart Tendler Belfast, By Kenneth Gosling Arts Reporter, From Trevor Fishlock Criccieth, By David Leigh, By Our Social Services Correspondent, From Harry Golombek chess Correspondent, By a Staff Reporter, By Hugh Clayton Agricultural Correspondent, By Diana Geddes, From John Chartres, By Our Agricultural Correspondent, By John Young, By Neville Hodgkinson, From Richard Wigg, From Our Own Correspondent, From Peter Hazelhurst, From Frank Vogl, From Mario modiano, From Patrick Brogan, From Eric Marsden, By John Woodcock Cricket Correspondent, By John Nicholls, By Neil Allen Athletics Correspondent, By Peter Ryde Golf Correspondent, By Michael Phillips Racing Correspondent, Katie Stewart, Irving Wardle, Stanley Sadie, Joan Chissell, Paul Griffiths, Charles Lewsen, William Gaunt, Alan Coren, Roy Lewis, Dessa Trevisan, PHS, Pearce Wright Science Editor, Ian Gilmour and Dennis Walters, E. O. LANE, , MARGARET HIGGINSON, , PAUL SANDERSON, , MALIN SORSBIE, , ALASTAIR BURNET, , ELIZABETH HARRISON, , LEONARD SCHAPIRO, , A. CAMERON, , C. J. YONGE, , HARRY O. MORTON, , JEAN B. PATEMAN, , By Our Horticultural Correspondent, A correspondent, E. F., Norman Collins, By Peter Hill Industrial Correspondent, By Andrew Goodrick-Clarke Financial Editor, By Malcolm Brown, By Our Economics Staff, From Peter Norman, Bv Tim Congdon, From David Cross, By Christopher Wilkins, By Our Financial Staff, By Peter Hill, Patricia Tisdall, By David Young, David Levack, VICTOR ROSS, , ALAN G. DARBY, , A. R. SWANNACK, , J. R. PARR, , By Arthur Reed, R. N. COHEN, , BY THE FINANCIAL EDITOR, Arthur Reed,
... the growing nuclear peril?, The Times Diary Some hedgehog mysteries remain, Farmers' report appeals for easing of ... it alone on tighter code, Rolls and Pratt engine proposal, Shotton men see Mr Foot, EEC informal ...
1975 - Gale Group | TDA
... allow for homeostasis are mostly preserved from embryogenesis; Hedgehog, Notch, BMP, and Wnt pathways all fire up their engines—although some undergo age-dependent decline—with injury. ...
Tópico(s): Hip disorders and treatments
2015 - Lippincott Williams & Wilkins | Clinical Orthopaedics and Related Research
FROM OUR RACING CORRESPONDENT, FROM OUR SQUASH RACKETS CORRESPONDENT, FROM OUR BOXING CORRESPONDENT, FROM OUR SPECIAL CORRESPONDENT, FROM OUR BILLIARDS CORRESPONDENT, FROM OUR CORRESPONDENT, FROM OUR OWN CORRESPONDENT, FROM OUR CORRESPONDENTS, FROM OUR AERONAUTICAL CORRESPONDENT, FROM OUR ARCHITECTURAL CORRESPONDENT, PATRICK ABERCROMBIE., RICHARD F. PHILLIMORE, PERCY J. WALDRAM., WILLIAM PALMER, JAMES JOHNSTON ABRAHAM, STANLEY CASSON., FROM OUR MOTORING CORRESPONDENT, FROM OUR LABOUR CORRESPONDENT, By CALLISTHENES, FROM OUR NEW YORK CORRESPONDENT, From Our Helsingfors Correspondent, FROM OUR DIPLOMATIC CORRESPONDENT, FROM OUR LEAGUE CORRESPONDENT, From Our Parliamentary Correspondent, J. VERNON BARTLET., ABE BAILEY., E. DENISON ROSS., JAMES MARCHANT., A. H. POLLEN, S. HODGSON., READING, By W. Roberts, A correspondent, Mr. George Corner, Mr. Alfred Thornton, Major Sir Algernon Tudor-Craig, A friend, FROM OUR WEATHER CORRESPONDENT, FROM OUR PARLIAMENTARY CORRESPONDENT, Our Parliamentary Correspondent, FROM OUR BRIDGE CORRESPONDENT, FROM A CORRESPONDENT,
... Interpreting Democracy To The World, Jemima A Friendly Hedgehog, Road Transport Wages State Control Opposed, Suspense In ...
1936 - Gale Group | TDA
Chahat Garg, Heena Khan, Amarjot Kaur, Thakur Gurjeet Singh, Vivek Sharma, Sachin Kumar Singh,
... A systemic review was conducted through various search engines to understand the molecular nature of Shh Pathway in Metabolic Disorders and its therapeutic implication in the future. However, we could find that by studying the crosstalk between various pathways, such as Wnt/ β-catenin, TGF (transforming growth factor β), mTOR, and notch with Sonic hedgehog, a close link between the pathogenesis of different ...
Tópico(s): Ethics and Legal Issues in Pediatric Healthcare
2022 - Elsevier BV | Pharmacological Research
Anna Dahlén, Christopher D.�M. Fletcher, Fredrik Mertens, Jonathan A. Fletcher, Antonio R. Pérez‐Atayde, John Hicks, Maria Dębiec‐Rychter, Raf Sciot, Johan Wejde, Rikard Wedin, Nils Mandahl, Ioannis Panagopoulos,
... oncogene is an important step in the sonic hedgehog signaling pathway, and leads to, eg, tissue-specific ... SMOH (smoothened) genes, encoding components of the sonic hedgehog pathway, or by amplification of GLI. Herein, we ... oncogene is an important step in the sonic hedgehog signaling pathway, and leads to, eg, tissue-specific ... SMOH (smoothened) genes, encoding components of the sonic hedgehog pathway, or by amplification of GLI. Herein, we ... constitute the last known step in the sonic hedgehog (SHH) signaling pathway, and they thus function as ...
Tópico(s): Oral and gingival health research
2004 - Elsevier BV | American Journal Of Pathology
... Archilochus, 'The fox knows many things, but the hedgehog knows one big thing.' For Berlin, the hedgehog stands for the type of thinkers who 'relate ... In this sense, Mancur Olson was the ultimate hedgehog of the social sciences. Most of his research ... bucolic' bees pollinating flowers, and sparks from railway engines setting fire to fields. Olson played a substantial ...
Tópico(s): Economic theories and models
1999 - Oxford University Press | The Economic Journal
Jarema Malicki, Colin A. Johnson,
... compartment for Gli–Sufu complexes, the effectors of Hedgehog signaling. Examples of cilia from a variety of ... compartment for Gli–Sufu complexes, the effectors of Hedgehog signaling. Examples of cilia from a variety of ... Figure II) [96Jahn R. Scheller R.H. SNAREs–engines for membrane fusion.Nat. Rev. Mol. Cell Biol. ...
Tópico(s): Microtubule and mitosis dynamics
2016 - Elsevier BV | Trends in Cell Biology
Pamela Jo Harris, Giovanna Speranza, Claudio Dansky Ullmann,
The embryonic signaling pathways (ESP), Hedgehog, Notch and Wnt, are critical for the regulation of normal stem cells and cellular development processes. They are also activated in ... The data sources utilized are several database search engines (PubMed, Google, Clinicaltrials.gov), and the authors' involvement ...
Tópico(s): Cancer-related Molecular Pathways
2012 - Taylor & Francis | Expert Opinion on Therapeutic Targets
Heinrich Taegtmeyer, Antony Rodríguez,
... et al. Drosophila genome-wide obesity screen reveals hedgehog as a determinant of brown versus white adipose ...
Tópico(s): Genetics, Aging, and Longevity in Model Organisms
2012 - Lippincott Williams & Wilkins | Circulation Research
Produção Nacional
Revisado por pares
Héctor N. Seuánez, J.L. Armada, C.M. Barroso, Cleiton Fantin Rezende, V.F. da Silva,
... comparison was made between the Algerian and Asian hedgehogs, where marked differences in the content of constitutive ...
Tópico(s): Genetic diversity and population structure
1983 - Karger Publishers | Cytogenetic and Genome Research
Cristina Correia, Taylor M. Weiskittel, Choong Yong Ung, José C. Villasboas, Daniel D. Billadeau, Scott H. Kaufmann, Li Hu,
... including signaling pathways (for example, WNT, Notch and Hedgehog), cell surface molecules that interact with cellular niche ... envision how systems pharmacology can become a major engine for discovery of novel targets and drug candidates ...
Tópico(s): 3D Printing in Biomedical Research
2022 - Frontiers Media | Frontiers in Cell and Developmental Biology
Zhen Yan, Sangdun Choi, Xuebin Liu, Mei Zhang, Jeoffrey Schageman, Sun Young Lee, Rebecca Hart, Ling Lin, Frederick A. Thurmond, R. Sanders Williams,
... box phosphate-buffered saline retinoblastoma reverse transcription sonic hedgehog tibialis anterior Skeletal muscles are damaged and repaired ... primer pairs were designed using a Primer3 search engine at www-genome.wi.mit.edu. The screened ...
Tópico(s): GDF15 and Related Biomarkers
2003 - Elsevier BV | Journal of Biological Chemistry