Periódicos nacionais
The Hehe now live mainly in the Iringa and Mufundi districts of Tanzania. Little is known of their early ... Usangu and Ungoni. After Munyigumba/s death the Hehe suffered a temporary set-back when Mwambambe, who ... his father/s lands, and under him the Hehe, who had only recently acquired political unity, had ... Germans' effort to make peace with them, the Hehe persisted in attacking caravans and the people who ... Uhehe. This was ambushed and defeated by the Hehe, who then continued their raids, causing the Germans ...
Tópico(s): African history and culture studies
1968 - Cambridge University Press | The Journal of African History
National Library of Medicine (NCBI)
Zhuangsheng Liu, Lilei Yi, Junhao Chen, Ruqiong Li, Keming Liang, Xiangmeng Chen, Ronggang Li, Wansheng Long,
Abstract Background Comparisons of hepatic epithelioid hemangioendothelioma (HEHE), hepatic hemangioma, and hepatic angiosarcoma (HAS) have rarely been reported. The purpose of our study was to analyze the clinical and magnetic resonance ... of 57 patients (25 with hemangioma, 13 with HEHE, and 19 with HAS) provided hepatic vascular endothelial ... 13), and 31.6% (6/19) for hemangioma, HEHE, and HAS, respectively ( P < 0.001). HAS lesions ... 13), and 36.8% (7/19) for hemangioma, HEHE, and HAS, respectively ( P = 0.014). HEHE and ...
Tópico(s): Vascular Malformations and Hemangiomas
2020 - BioMed Central | BMC Medical Imaging
Hepatic epithelioid hemangioendothelioma (HEHE) is a rare hepatic vascular tumor with unpredictable malignant potential. The etiology, characteristics, diagnosis, treatment, and prognosis of HEHE are not well-understood, and large-scale retrospective ... better this disease.To determine the characteristics of HEHE and identify its optimal treatments and prognostic factors.The clinical data of two patients diagnosed with HEHE at the Fourth Hospital of Hebei Medical University ... and summarized. All cases were pathologically identified as HEHE. Information such as clinical features, laboratory examination findings, ...
Tópico(s): Cardiac tumors and thrombi
2022 - Baishideng Publishing Group | World Journal of Clinical Cases
Mihir Brahmbhatt, Stacey Prenner, Therese Bittermann,
Hepatic epithelioid hemangioendothelioma (HEHE) is a rare vascular tumor with a high mortality rate. HEHE is now a formally recognized indication for exception ... priority in the United States for patients with HEHE remains understudied.This was a retrospective cohort study ... 31, 2018, 131 adults waitlisted for LT with HEHE were identified by free-text entry.Exception point ... 5-237.5). Unadjusted post-LT survival of HEHE recipients at 1-, 3-, and 5-years from ... Unadjusted post-LT patient and graft survival of HEHE patients was not different from patients with hepatocellular ...
Tópico(s): Histiocytic Disorders and Treatments
2019 - Wolters Kluwer | Transplantation
Nobu Oshima, Hiroaki Terajima, Ryo Hosotani,
Hepatic epithelioid hemangioendothelioma (HEHE) is a rare neoplasm of vascular origin. The clinical presentation of HEHE is variable, and the therapeutic criteria are still ... liver. She had undergone segmental hepatectomy for solitary HEHE in segment VII 10 years before. There had ... tumor was diagnosed as a new lesion of HEHE by percutaneous needle liver biopsy, and thereafter repeated hepatectomy was performed. HEHE seems to be resistant to chemotherapy and radiotherapy. ... as a curative treatment for this disease. However, HEHE tends to be detected in multiple lesions, and ...
Tópico(s): Acute Myeloid Leukemia Research
2009 - Karger Publishers | Case Reports in Gastroenterology
Carmine Nudo, Eric M. Yoshida, Vincent G. Bain, Denis Marleau, Phil Wong, Paul J. Marotta, Eberhard L. Renner, Kymberly D. Watt, Marc Deschênes,
Hepatic epithelioid hemangioendothelioma (HEHE) is a rare entity. At the present time, there is no standardized effective therapy. Liver transplantation (LT) has emerged ... To evaluate the outcome of liver transplantation for HEHE at eight centres across Canada.The charts of patients who were transplanted for HEHE at eight centres across Canada were reviewed.A ... women and three men) received a LT for HEHE. All LTs were performed between 1991 and 2005. ... months). Four patients (36.4%) developed recurrence of HEHE with a mean time to recurrence of 25+/- ...
Tópico(s): Histiocytic Disorders and Treatments
2008 - Pulsus Group | Canadian Journal of Gastroenterology
Quirino Lai, E. Feys, Vincent Karam, René Adam, Jürgen Klempnauer, Martin Oliverius, Vincenzo Mazzaferro, Andreas Pascher, Piotr Remiszewski, Helena Isoniemi, Jacques Pirenne, Aksel Foss, B.-G. Ericzon, Saša Marković, Jan Lerut,
Background Hepatic epithelioid hemangioendothelioma (HEHE) is a rare vascular tumor which has an intermediate aggressive behavior. Although the value of liver transplantation (LT) is well established, its place in the management of HEHE is still unclear. The aim of this study ... the value of LT in the management of HEHE and to identify risk factors for post-LT ... Methods The outcome of 149 transplant recipients with HEHE recorded in the European Liver Transplant Registry during ... propensity score analysis, allowed the development of a HEHE-LT score enabling stratification of patients in relation ...
Tópico(s): Occupational and environmental lung diseases
2016 - Wolters Kluwer | Transplantation
Krzysztof Mucha, Bartosz Foroncewicz, Krzysztof Zieniewicz, P Nyckowski, Marek Krawczyk, Anna Cyganek, Leszek Pączek,
... liver, lungs and other organs. Its hepatic form (HEHE) generally behaves as a low-grade malignant tumor ... present a 30-year-old woman with primary HEHE of the liver treated by OLT in 2002. ... of chemotherapy, a laparoscopic biopsy was performed and HEHE diagnosed. Immunohistochemistry revealed positive staining for the factor ... and CD31, which have been previously described as HEHE markers. The patient underwent OLT in March 2002. ... cell markers may facilitate the correct diagnosis of HEHE. After diagnosis, OLT followed by immunosuppressive therapy, consisting ...
Tópico(s): Vascular Malformations and Hemangiomas
2006 - Elsevier BV | Transplantation Proceedings
Lisha Zhou, Minyi Cui, Juxin Xiong, Zhi Dong, Yanji Luo, Hui Xiao, Ling Xu, Kun Huang, Ziping Li, Shi‐Ting Feng,
... resonance imaging(MRI) characteristics of hepatic epithelioid hemangioendothelioma (HEHE).Eleven patients with histopathologically confirmed HEHE via surgical excision or biopsy were included. Imaging ... enhancement, and changes of adjacent tissues were evaluated.HEHE is characterized by multiple lesions in the liver. HEHE could be further categorized as three types when ... 26/32, 81.3%).The imaging findings of HEHE showed some typical imaging features and size-dependent ... can be used for accurate imaging diagnosis of HEHE.
Tópico(s): Eosinophilic Disorders and Syndromes
2015 - BioMed Central | BMC Gastroenterology
Kai Kou, Yuguo Chen, Jianpeng Zhou, Xiaodong Sun, Dawei Sun, Shuxuan Li, Guoyue Lv,
... in every 1 million people, hepatic epithelioid hemangioendothelioma (HEHE) is a rare vascular endothelial cell tumor occurring ... endothelial cells in mucus or a fibrotic matrix. HEHE is characterized as a low-to-moderate grade ... Both the etiology and characteristic clinical manifestations of HEHE are unclear. However, HEHE has a characteristic appearance on imaging including ultrasound, ... literature related to the diagnosis and treatment of HEHE, which provides future perspectives for the clinical management ...
Tópico(s): Cardiac tumors and thrombi
2020 - Baishideng Publishing Group | World Journal of Clinical Cases
Khalid Sharif, Martin English, P Ramani, Daniela Alberti, Jean-Bernard Otte, P. J. McKiernan, Serge Gosseye, Meriel Jenney, Jean de Ville de Goyet,
Hepatic epithelioid haemangio-endothelioma (HEHE) is an endothelium-derived tumour of low-to-medium grade malignancy. It is predominantly seen in adults and is unresponsive ... of three European centres in the management of HEHE in children. A retrospective review of all paediatric patients with HEHE managed in three European centres is presented. Five ... months after the use of platinum-based chemotherapy. HEHE seems more aggressive in children than reported in ... effective. Further studies are necessary to confirm if HEHE progression in children may be influenced by platinum- ...
Tópico(s): Cardiac tumors and thrombi
2004 - Springer Nature | British Journal of Cancer
Jan Lerut, Giuseppe Orlando, Christine Sempoux, Olga Ciecarelli, Bernard E. Van Beers, E. Danse, Yves Horsmans, Jacques Rahier, Francine Roggen,
Abstract Hepatic epithelioid haemangioendotheliomas (HEHEs) are rare, low-grade vascular tumours. Five adults with HEHEs and one adult with a vascular tumour showing combined features of haemangioma and haemangioendothelioma underwent liver transplantation. Two HEHE patients had extrahepatic metastases at the time of ... 195 months). One patient needed resection of a HEHE in the breast 13 years post-transplantation. All ... 166 months after transplantation (median 77 months). One HEHE-patient who had been treated for 8 years ...
Tópico(s): Tuberous Sclerosis Complex Research
2004 - Springer Science+Business Media | Transplant International
Christine Sempoux, Bernard E. Van Beers, E. Danse, Yves Horsmans, Jacques Rahier, Francine Roggen, Jan Lerut, Giuseppe Orlando, Olga Ciccarelli,
Hepatic epithelioid haemangioendotheliomas (HEHEs) are rare, low-grade vascular tumours. Five adults with HEHEs and one adult with a vascular tumour showing combined ... of haemangioma and haemangioendothelioma underwent liver transplantation. Two HEHE patients had extrahepatic metastases at the time of ... 195 months). One patient needed resection of a HEHE in the breast 13 years post-transplantation. All ... 166 months after transplantation (median 77 months). One HEHE-patient who had been treated for 8 years ...
Tópico(s): Tuberous Sclerosis Complex Research
2004 - Springer Science+Business Media | Transplant International
... outcomes of liver transplantation for hepatic epithelioid hemangioendothelioma (HEHE).Between 1989 and August 2013, in the Department ... transplantations (OLTx) were performed, including 72 retransplantations. Unresectable HEHE was an indication for OLTx in 10 patients ( ... was 2:8. Kaplan-Meier survival analysis in HEHE, hepatocellular carcinoma (HCC), and other OLTx recipients groups ... rate at the end of follow-up in HEHE patients was 87.5% compared with 54.3% ... 1.784, df = 2, P = 0.409).Unresectable HEHE, without extrahepatic metastases is an excellent indication for ...
Tópico(s): Histiocytic Disorders and Treatments
2014 - Baishideng Publishing Group | World Journal of Gastroenterology
Xinyan Zhao, MOHMEDMOHSIN ISMAIL AHMED RAKHDA, Sohail Habib, Ali Bihi, Abdullah Muhammad, Tai Ling Wang, Jidong Jia,
Hepatic epithelioid hemangioendothelioma (HEHE) is a rare tumor of vascular origin. Whether HEHE in Chinese patients exhibits similar characteristics compared with Western patients ... present study was to summarize the characteristics of HEHE in Chinese patients and identify its prognostic factors. In total, six patients diagnosed with HEHE at the Beijing Friendship Hospital between 2000 and ... unfavorable outcomes. In contrast to Western patients with HEHE, a larger number of Chinese patients were asymptomatic ...
Tópico(s): Cardiac tumors and thrombi
2014 - Spandidos Publishing | Oncology Letters
Yi Dong, Wen‐Ping Wang, Vito Cantisani, Mirko D’Onofrio, A Ignee, Lorenzo Mulazzani, Adrian Săftoiu, Zeno Spârchez, Ioan Sporea, Christoph F. Dietrich,
... CEUS) features of histologically proven hepatic epithelioid hemangioendothelioma (HEHE) in comparison to other multilocular benign focal liver ... FLL). METHODS:Twenty-five patients with histologically proven HEHE and 45 patients with histologically proven multilocular benign ... assessed the CEUS enhancement pattern in consensus.RESULTS: HEHE manifested as a single (n = 3) or multinodular (n = 22) FLL.On CEUS, HEHE showed rim-like (18/25, 72%) or heterogeneous ... PVLP, CEUS can determine the malignant nature of HEHE.
Tópico(s): Tuberous Sclerosis Complex Research
2016 - Baishideng Publishing Group | World Journal of Gastroenterology
... the rare and intermediately aggressive hepatic epithelioid haemangioendothelioma (HEHE) to the rare and most malignant hepatic haemangiosarcoma ( ... cholangiocellular cancer, the diagnostic and therapeutic approaches to HEHE and HHS are not well developed. The related ... possible, because it is the therapeutic mainstay. In HEHE, LT provides excellent results, with long-term disease- ... Based on the extensive ELITA-ELTR study a HEHE-LT prognostic score has been proposed in order ... important recurrence rate after surgical resection (25% in HEHE and almost 100% in HHS), there is an ...
Tópico(s): Vascular Malformations and Hemangiomas
2018 - AME Publishing Company | Translational Gastroenterology and Hepatology
... in patients with pathologically confirmed hepatic epithelioid hemangioendothelioma (HEHE).Findings from imaging examinations in 8 patients (5 women and 3 men) with pathologically confirmed HEHE were retrospectively reviewed (CT images obtained from 7 ... 39.8 years).There were two types of HEHE: multifocal type (n = 7) and diffuse type (n = ... and MRI.The most important imaging features of HEHE are the target sign and/or progressive enhancement ...
Tópico(s): Occupational and environmental lung diseases
2011 - Baishideng Publishing Group | World Journal of Gastroenterology
Pedro Baron, Thomas Amankonah, Robert F. Cubas, Arputharaj Kore, Arvand Elihu, Michael E. de Vera, Mia C. Perez,
Hepatic epithelioid hemangioendothelioma (HEHE) is an infrequent vascular tumor of endothelial origin that primarily occurs in women in the mid-fifth decade of ... multiple confluent infiltrating bilobar liver masses diagnosed as HEHE. She underwent a successful liver transplant without evidence ... HCV infection. She developed cervical spine (C4-C6) HEHE metastases 4 years after transplant. She underwent surgical ... our knowledge, this is the first report of HEHE that developed in a patient with HCV cirrhosis ...
Tópico(s): CNS Lymphoma Diagnosis and Treatment
2014 - Hindawi Publishing Corporation | Case Reports in Transplantation
Ryan M. Thomas, Thomas A. Aloia, Mark J. Truty, Warren H. Tseng, Eugene A. Choi, Steven A. Curley, Jean‐Nicolas Vauthey, Eddie K. Abdalla,
The biology of hepatic epithelial haemangioendothelioma (HEHE) is variable, lying intermediate to haemangioma and angiosarcoma. Treatments vary owing to the rarity of the disease and frequent misdiagnosis.Between 1989 and 2013, patients retrospectively identified with HEHE from a single academic cancer centre were analysed ... regimens associated with survival.Fifty patients with confirmed HEHE had a median follow-up of 51 months ( ... CI 0.9-10.7), P = 0.02].HEHE frequently follows an indolent course, suggesting that immediate ...
Tópico(s): Cardiac tumors and thrombi
2013 - Elsevier BV | HPB
Kyriakos Neofytou, Andreas Chrysochos, N Charalambous, Menelaos Dietis, Christos Petridis, Charalampos Andreou, Athanasios Petrou,
Malignant hepatic epithelioid hemangioendothelioma (HEHE) is a rare malignant tumor of vascular origin. Nonspecific symptoms and the absence of experience of surgeons, radiologists, and histopathologists due to the rarity of HEHE make the diagnosis of this entity very challenging. ... report a case of a patient suffering from HEHE in which the initial diagnosis was hepatocellular carcinoma ( ... tumors. The last biopsy confirmed the diagnosis of HEHE, and the patient escaped any unnecessary treatment for ...
Tópico(s): Acute Myeloid Leukemia Research
2013 - Hindawi Publishing Corporation | Case Reports in Oncological Medicine
... intermediate malignant potential.1-3 Hepatic epithelioid hemangioendothelioma (HEHE), a rare sarcoma of the liver, usually appears ... carcinoma on the basis of its radiologic manifestations. HEHE is composed of neoplastic endothelial cells that closely ... endothelial cell markers is critical for accurately diagnosing HEHE. In this issue, we present a case of HEHE in a 44-year-old woman and discuss ...
Tópico(s): Cardiac tumors and thrombi
2013 - Korean Association for the Study of the Liver | Clinical and Molecular Hepatology
Hai‐Jie Hu, Yanwen Jin, Qiuyang Jing, Anuj Shrestha, Nan-Sheng Cheng, Fu‐Yu Li,
Hepatic epithelioid hemangioendothelioma (HEHE) is a rare category of vascular tumor with uncertain malignant potential.It commonly presents nonspecific and variable clinical manifestations, ... features also lack specificity in the diagnosis of HEHE.The aim of the present study is to ... dilemma and challenges in the preoperative diagnosis of HEHE, and to enhance awareness of the range of ... hepatic nodular lesions on imaging.In these patients, HEHE should at least be considered in the differential ...
Tópico(s): Vascular Malformations and Hemangiomas
2016 - Baishideng Publishing Group | World Journal of Gastroenterology
Vladislav Třeška, Ondřej Daum, Marián Švajdler, Václav Liška, Jiří Ferda, Jan Baxa,
Hepatic epithelioid haemangio-endothelioma (HEHE) is a very rare malignant tumor of vascular origin and uncertain biological behaviour that is difficult to diagnose using preoperative ... techniques.The authors present here two patients with HEHE of different extent. The first patient had a ... 27 and 5 months respectively following treatment for HEHE.Preoperative radiological diagnosis of HEHE is difficult and immunohistochemical examination of the tumor ...
Tópico(s): Cardiac tumors and thrombi
2017 - Stanford University Highwire Press | In Vivo
Linping Cao, Jiawei Hong, Lingfeng Zhou, Yufu Ye, Yuanxing Liu, Jun Yu, Shusen Zheng,
Hepatic epithelioid hemangioendothelioma (HEHE) is a rare angiogenic tumor with no recognized effective treatment. Treatment options used worldwide include liver transplantation (LT), liver ... the efficacy of different treatment options used for HEHE at our center.The medical charts of 12 patients with HEHE (9 women and 3 men) who were diagnosed ... 15-82 months).There are multiple strategies for HEHE. Considering its indolent course, initial observation for assessment ...
Tópico(s): Vascular Malformations and Hemangiomas
2019 - BioMed Central | World Journal of Surgical Oncology
Constanza Martínez, Jonathan Lai, Daryl Ramai, Antonio Facciorusso, Zu‐Hua Gao,
... liver: hepatic angiosarcomas (HA) and hepatic epithelioid hemangioendotheliomas (HEHE).Data on HA and HEHE between 1975 and 2016 were extracted from the ... overall survival for HA was 2 months. For HEHE, 120 cases were identified, 32.5% were male ... is an aggressive tumor despite intervention. Patients with HEHE tumors have significantly better survival compared to patients ...
Tópico(s): Histiocytic Disorders and Treatments
2021 - Wiley | Cancer Medicine
Christof Kaltenmeier, Silvia Stacchiotti, Alessandro Gronchi, Gonzalo Sapisochín, Hao Liu, Eishan Ashwat, Vikraman Gunabushanam, Dheera Reddy, Ann Thompson, David A. Geller, Samer Tohme, Amer H. Zureikat, Michele Molinari,
... the outcomes of patients with hepatic epithelioid hemangioendothelioma (HEHE) in the United States after stratification by their ... Data Base was used to identify patients with HEHE between 2004 and 2018. Patients were divided in ... outcomes of the largest cohort of patients with HEHE. The longest survival was observed after liver transplantation, ... used for the selection of treatment modalities for HEHE are urgently needed.
Tópico(s): Histiocytic Disorders and Treatments
2022 - Elsevier BV | HPB
Hepatic epithelioid hemangioendothelioma (HEHE) is a rare malignant tumor characterized by its epithelioid structure and vascular endothelium origin. The clinical course of HEHE is variable, ranging from long-term survival without ... has been determined. We present a case of HEHE occurring in a 13-year-old girl, in ...
Tópico(s): Eosinophilic Disorders and Syndromes
2008 - Lippincott Williams & Wilkins | Journal of Pediatric Hematology/Oncology