Jost Ludwig, Heinrich Terlau, Frank Wunder, Andrea Brüggemann, Luis A. Pardo, Annette Marquardt, Walter Stühmer, Olaf Pongs,
We have cloned a mammalian (rat) homologue of Drosophila ether á go-go (eag) cDNA, which encodes a distinct type of voltage activated potassium (K) channel. The derived Drosophila and rat eag polypeptides share > 670 amino acids, with a sequence identity of 61%, exhibiting a high degree of similarity at the N-terminus, the hydrophobic core including the pore forming P region and a potential cyclic nucleotide binding site. Rat eag mRNA is specifically expressed in the central nervous system. In the Xenopus ...
Tópico(s): Cardiac electrophysiology and arrhythmias
1994 - Springer Nature | The EMBO Journal
Vadim O. Chagin, Britta Reinhart, Annette Becker, Oliver Mortusewicz, Katharina Laurence Jost, Alexander Rapp, Heinrich Leonhardt, M. Cristina Cardoso,
Constitutive heterochromatin is considered as a functionally inert genome compartment, important for its architecture and stability. How such stable structure is maintained is not well understood. Here, we apply four different visualization schemes to label it and investigate its dynamics during DNA replication and repair. We show that replisomes assemble over the heterochromatin in a temporally ordered manner. Furthermore, heterochromatin undergoes transient decompaction locally at the active sites ...
Tópico(s): Bacterial Genetics and Biotechnology
2019 - Taylor & Francis | Nucleus
C. A. M. Brenninkmeijer, Paul J. Crutzen, Hubertus Fischer, H. Güsten, W. Hans, G. Heinrich, Jost Heintzenberg, M. Hermann, T. Immelmann, D. Kersting, Manfred Maiss, Michael Nölle, A. Pitscheider, H. Pohlkamp, D. Scharffe, K. Specht, Alfred Wiedensohler,
The deployment of measurement equipment in passenger aircraft for the observation of atmospheric trace constituents is described. The package of automated instruments that is installed in a one-ton-capacity aircraft freight container positioned in the forward cargo bay of a Boeing 767 ER can register a vast amount of atmospheric data during regular long-distance flights. The air inlet system that is mounted on the fuselage directly below the container comprises an aerosol inlet, a separate inlet ...
Tópico(s): Atmospheric and Environmental Gas Dynamics
1999 - American Meteorological Society | Journal of Atmospheric and Oceanic Technology
Three Jewish Historians: Isaak Markus Jost – Heinrich Graetz – Eugen Taeubler Get access Georg Herlitz Georg Herlitz Search for other works by this author on: Oxford Academic Google Scholar ...
1964 - Oxford University Press | The Leo Baeck Institute Year Book
Heinrich Terlau, Jost Ludwig, Rüdiger Steffan, Olaf Pongs, Walter Stühmer, Stefan H. Heinemann,
Tópico(s): Ion Channels and Receptors
1996 - Springer Science+Business Media | Pflügers Archiv - European Journal of Physiology
Tópico(s): German Literature and Culture Studies
1959 - | Modern Language Notes
Jeffrey L. Sammons, Heinrich Heine, Jost Hermand, Robert C. Holub,
The German Library is a new series of the major works of German literature and thought from medieval times to the present. The volumes have forewords by internationally known writers and introductions by prominent scholars. Here the English-speaking reader can find the broadest possible collection of poetic and intellectual achievements in new as well as great classic translations. Convenient and accessible in format, the volumes of The German Library will form the core of any growing library of ...
1987 - Wiley | Modern Language Journal
Jocelyne Kolb, Heinrich Heine, Jost Hermand, Robert C. Holub,
1987 - Wiley | Die Unterrichtspraxis/Teaching German
Sandrine Koechler, Florence Arsène‐Ploetze, Céline Brochier‐Armanet, Florence Goulhen-Chollet, Audrey Heinrich-Salmeron, Bernard Jost, Didier Lièvremont, Muriel Philipps, Frédéric Plewniak, Philippe Bertin, Marie-Claire Lett,
Pseudomonas xanthomarina S11 is an arsenite-oxidizing bacterium isolated from an arsenic-contaminated former gold mine in Salsigne, France. This bacterium showed high resistance to arsenite and was able to oxidize arsenite to arsenate at concentrations up to 42.72 mM As[III]. The genome of this strain was sequenced and revealed the presence of three ars clusters. One of them is located on a plasmid and is organized as an “arsenic island” harbouring an aio operon and genes involved in phosphorous ...
Tópico(s): Chromium effects and bioremediation
2015 - Elsevier BV | Research in Microbiology
Ulrich Otto, Ingrid Heinrich-Jost, Reinhard Pozorny, Roland Schlink,
1985 - De Gruyter | Jahrbuch für Volksliedforschung
M. Hermann, Jost Heintzenberg, Alfred Wiedensohler, Andreas Zahn, G. Heinrich, Carl A. M. Brenninkmeijer,
Number concentrations of submicrometer aerosol particles at altitudes of 8.5–11.3 km were measured along a single flight route between Germany (∼50°N, ∼10°E) and the Indic (∼5°N, ∼80°E) over 3 years using a commercial aircraft platform (project Civil Aircraft for Regular Investigation of the Atmosphere Based on an Instrument Container (CARIBIC)). During 41 intercontinental flights (∼380 flight hours), more than one million individual particle concentration measurements were made, yielding a comprehensive ...
Tópico(s): Air Quality and Health Impacts
2003 - American Geophysical Union | Journal of Geophysical Research Atmospheres
Andreas Zahn, C. A. M. Brenninkmeijer, Manfred Maiss, D. Scharffe, Paul J. Crutzen, M. Hermann, Jost Heintzenberg, Alfred Wiedensohler, H. Güsten, G. Heinrich, H. Fischer, J. W. M. Cuijpers, P. van Velthoven,
Simultaneous measurements of O 3 , CO, and ultrafine aerosol particles (UFP), conducted on board of a Boeing 767‐ER passenger aircraft flying from Sri Lanka to Germany (project CARIBIC), are used to study two‐way cross‐tropopause mixing near a subtropical tropopause fold. On the equatorward side of the fold, downward mixing of stratospheric air into the upper troposphere is identified by enhanced concentrations of O 3 and 14 CO. Very high UFP number concentrations of up to 1.5×10 4 cm −3 (STP) were encountered ...
Tópico(s): Atmospheric and Environmental Gas Dynamics
2000 - American Geophysical Union | Journal of Geophysical Research Atmospheres
Robert Jütte, Michael Heinrich, Axel Helmstädter, Jost Langhorst, Meng Günter, Wilhelm Niebling, Tanja Pommerening, Hans J. Trampisch,
Aside from the fully licensed herbal medicines there are products on the European pharmaceutical market which are registered by virtue of their longstanding traditional use. The normal registration procedure does not apply to them because presently they do not meet the legal requirements for a full license as set out in the relevant European Union Directive. One of these requirements, "proof of tradition", has so far been dealt with in different ways and fails to meet the criteria of good practice. ...
Tópico(s): Botanical Studies and Applications
2017 - Elsevier BV | Journal of Ethnopharmacology
George F. Peters, Jost Hermand, Robert C. Holub, Heinrich Heine,
Contents: Jeffrey L. Sammons: Who Did Heine Think He Was? - Christhard Hoffmann: History versus Memory: Heinrich Heine and the Jewish Past - Bluma Goldstein: Heine's Hebrew Melodies: A Politics and Poetics of Diaspora - Robert C. Holub: Confessions of an Apostate: Heine's Conversion and Its Psychic Displacement - Hinrich C. Seeba: Keine Systematie: Heine in Berlin and the Origin of the Urban Gaze - Susanne Zantop: Columbus, Humboldt, Heine, or the Rediscovery of Europe - Jennifer Kapczynski/Kristin Kopp/Paul ...
Tópico(s): German Literature and Culture Studies
2000 - German Studies Association | German Studies Review
Congdi Song, Yana Feodorova, Jacky Guy, Leo Peichl, Katharina Laurence Jost, Hiroshi Kimurâ, M. Cristina Cardoso, Adrian Bird, Heinrich Leonhardt, Boris Joffe, Irina Solovei,
Methyl-CpG binding protein 2 (MECP2) is a protein that specifically binds methylated DNA, thus regulating transcription and chromatin organization. Mutations in the gene have been identified as the principal cause of Rett syndrome, a severe neurological disorder. Although the role of MECP2 has been extensively studied in nervous tissues, still very little is known about its function and cell type specific distribution in other tissues. Using immunostaining on tissue cryosections, we characterized ...
Tópico(s): RNA modifications and cancer
2014 - BioMed Central | Epigenetics & Chromatin
Noopur Agarwal, Annette Becker, Katharina Laurence Jost, Sebastian Haase, Basant Kumar Thakur, Alessandro Brero, Tanja Hardt, Shinichi Kudo, Heinrich Leonhardt, M. Cristina Cardoso,
Rett syndrome is a neurological, X chromosomal-linked disorder associated with mutations in the MECP2 gene. MeCP2 protein has been proposed to play a role in transcriptional regulation as well as in chromatin architecture. Since MeCP2 mutant cells exhibit surprisingly mild changes in gene expression, we have now explored the possibility that Rett mutations may affect the ability of MeCP2 to bind and organize chromatin. We found that all but one of the 21 missense MeCP2 mutants analyzed accumulated ...
Tópico(s): Genomic variations and chromosomal abnormalities
2011 - Oxford University Press | Human Molecular Genetics
John B. Franklin, Robert L. Brent,
... M.A. J. Dis. Child., 80: 34–45. Jost, A. 1946 Experiences de decapitation de l'embryon de lapin. C. R. Acad. Sci. (Paris), 140: 461–462. Knese, Karl-Heinrich 1960 Untersuchungen über die Reaktion der Gewebe von ...
Tópico(s): Pluripotent Stem Cells Research
1964 - Wiley | Journal of Morphology
Andreas Zahn, C. A. M. Brenninkmeijer, P. J. Crutzen, D. D. Parrish, D. Sueper, G. Heinrich, H. Güsten, H. Fischer, M. Hermann, Jost Heintzenberg,
In situ trace gas (O 3 , NO, NO 2 , NO y ) and ultrafine aerosol particle data from a passenger aircraft (project CARIBIC) and the NOAA WP‐3D research aircraft are used to identify the origin of “ozone‐rich transients” that occasionally appear in aircraft ozone data sets along flight distances of 5–80 km. Evidence of ozone import from the stratosphere, once suggested as the most likely cause, cannot be found. Our data rather reveal that the majority of the recorded ozone transients are artifacts caused by ...
Tópico(s): Lightning and Electromagnetic Phenomena
2002 - American Geophysical Union | Journal of Geophysical Research Atmospheres
Heinrich Terlau, Stefan H. Heinemann, Walter Stühmer, Olaf Pongs, Jost Ludwig,
Rat eag potassium channels (r‐eag) were expressed in Xenopus oocytes. They gave rise to delayed rectifying K + currents with a strong Cole‐Moore effect. Deletions in the N‐terminal structure of r‐eag either shifted the activation threshold to more negative potentials and slowed the activation kinetics (Δ2–190, Δ2–12 and Δ7–12) or resulted in a shift to more positive potentials and faster activation kinetics (Δ150–162). The impact of the deletion Δ7–12 was investigated in more detail: it almost abolished ...
Tópico(s): Neuroscience and Neuropharmacology Research
1997 - Wiley | The Journal of Physiology
... the nineteenth-century—men such as Isaac M. Jost (1793–1860), Heinrich Graetz (1817–1891), and Simon Dubnow (1860–1941)— ...
Tópico(s): Medieval and Classical Philosophy
2017 - Johns Hopkins University Press | American Jewish history
Jost von Hardenberg, Maike Schwartz, Thorsten Werner, Stefan Fuxius, Markus Müller, Christian Bolenz, Christel Weiß, Elmar Heinrich,
BACKGROUND Abiraterone Acetate (AA) represents a highly effective androgen-receptor (AR) axis targeted agent. Treatment with AA in castration-resistant prostate cancer (CRPC) may partly mediate neuroendocrine differentiation (NED) as an escape mechanism, which may have implications for the choice of sequential therapy in CRPC. We evaluated how treatment with AA influences circulating neuromediators chromogranin A (CGA), neuron-specific enolase (NSE), and pro-gastrin-releasing peptide (Pro-GRP) in chemotherapy- ...
Tópico(s): Radiopharmaceutical Chemistry and Applications
2016 - Wiley | The Prostate
... 1992), while Daniel Magilow examines perpetrator photographs through Heinrich Jöst's Warsaw ghetto pictures; Sven-Erik Rose examines ...
Tópico(s): Photography and Visual Culture
2010 - Purdue University Press | Shofar
... lack' (p. 32). Daniel H. Magilow looks at Heinrich Jost's photographs of theWarsaw ghetto (which firstemerged in ...
Tópico(s): Philosophy, Ethics, and Existentialism
2010 - Modern Humanities Research Association | The Modern Language Review
Katharina Laurence Jost, Andrea Rottach, Manuela Milden, Bianca Bertulat, Annette Becker, Patricia Wolf, Juan Sandoval, Paolo Petazzi, Dori Huertas, Manel Esteller, Elisabeth Kremmer, Heinrich Leonhardt, M. Cristina Cardoso,
Methyl CpG binding protein 2 (MeCP2) binds DNA, and has a preference for methylated CpGs and, hence, in cells, it accumulates in heterochromatin. Even though it is expressed ubiquitously MeCP2 is particularly important during neuronal maturation. This is underscored by the fact that in Rett syndrome, a neurological disease, 80% of patients carry a mutation in the MECP2 gene. Since the MECP2 gene lies on the X chromosome and is subjected to X chromosome inactivation, affected patients are usually ...
Tópico(s): Genomic variations and chromosomal abnormalities
2011 - Public Library of Science | PLoS ONE
Bernd W. Böttiger, Burkhard Dirks, U Jost, U. Kreimeier, Stefan Osche, Markus Roeßler, Karl Heinrich Scholz, Sabine Wingen,
Sudden cardiac death due to out-of-hospital cardiac arrest is the third leading cause of mortality in industrialised nations.1–3 In Europe and in the USA, 800 000 people die every year despite the fact that the emergency medical services initially resuscitate them. The main problem is that emergency medical services take an average of 8 min – and often much more – before they arrive at the scene. The brain tissue, however, commences to die after 3 to 5 min. Therefore, resuscitation procedures initiated ...
Tópico(s): Trauma and Emergency Care Studies
2018 - Lippincott Williams & Wilkins | European Journal of Anaesthesiology
Jost von Hardenberg, Maike Schwartz, Thorsten Werner, Stefan Fuxius, Markus Müller, Thomas Frangenheim, Christian Bolenz, Christel Weiß, Elmar Heinrich,
Aim: Aim of the study was to detect small cell/neuroendocrine (SCNC) transformation in metastatic castration-resistant prostate cancer (mCRPC) that is a challenging procedure. We investigated the role of neuromediator dynamics as potential evidence of SCNC in patients undergoing docetaxel therapy. Patients and Methods: A multi-institutional, prospective observational study was conducted. Patients undergoing docetaxel treatment were included. Chromogranin A (CGA), neuron-specific enolase (NSE), and pro- ...
Tópico(s): Neuroendocrine Tumor Research Advances
2017 - International Institute of Anticancer Research (IIAR) Conferences 1997. Athens, Greece. Abstracts | Anticancer Research
George F. Peters, Jost Hermand,
Tópico(s): Art, Aesthetics, and Perception
1996 - German Studies Association | German Studies Review
Jost von Hardenberg, Maike Schwartz, Thorsten Werner, Stefan Fuxius, Arne Strauß, Thomas Stefan Worst, Philipp Nuhn, Christian Bolenz, Elmar Heinrich,
<b><i>Background:</i></b> Limited data are available for the use of agents in metastatic castration-resistant prostate cancer (mCRPC) beyond the third-line. We provide data during treatment with cabazitaxel (CAB), helping to improve the informed-consent process. <b><i>Patients and Methods:</i></b> We retrospectively reviewed patients treated with fourth-line or beyond CAB for mCRPC after failure of previous therapies with docetaxel, abiraterone acetate, ...
Tópico(s): Radiopharmaceutical Chemistry and Applications
2017 - Karger Publishers | Urologia Internationalis
... a careful observer but was not an experimentalist. (Heinrich) Anton de Bary (1831–1888) was the leading physiological mycologist and a leading phytopathologist of the 1800s and was an outstanding experimentalist (Whetzel 1918:45–47, Jost 1930, Robinson 1971, Sparrow 1978). He was also ...
Tópico(s): Yeasts and Rust Fungi Studies
2012 - Ecological Society of America | Bulletin of the Ecological Society of America
Todd C. Hanlin, Luther Erasmus, Muntzer Erasmus, Reinhard P. Becker, Schlegel Novalis, Schleiermacher Novalis, A. Leslie Willson, Heinrich von Kleist, Walter Hinderer, E. T. A. Hoffmann, Victor Lange, Heinrich Heine, Jost Hermand, Robert C. Holub, Gottfried Keller, Frank G. Ryder, Theodor Fontane, Peter Demetz, Friedrich Dürrenmatt, Volkmar Sander, Hans Magnus Enzensberger, Reinhold Grimm, Bruce K. Armstrong,
1984 - Wiley | Modern Language Journal