Limpar
2.224 resultados

Acesso aberto

Tipo do recurso

Ano de criação

Produção nacional

Revisado por pares

Áreas

Idioma

Editores

Artigo Brasil Produção Nacional Revisado por pares

Priscila Dabaghi-Barbosa, Priscila Dabaghi-Barbosa, Andreia Mariante Rocha, Priscila Dabaghi-Barbosa, Andreia Mariante Rocha, Anderson Franco da Cruz Lima, Priscila Dabaghi-Barbosa, Andreia Mariante Rocha, Anderson Franco da Cruz Lima, Brás Heleno de Oliveira, Priscila Dabaghi-Barbosa, Andreia Mariante Rocha, Anderson Franco da Cruz Lima, Brás Heleno de Oliveira, Maria Benigna Martinelli de Oliveira, Priscila Dabaghi-Barbosa, Andreia Mariante Rocha, Anderson Franco da Cruz Lima, Brás Heleno de Oliveira, Maria Benigna Martinelli de Oliveira, Eva Gunilla Skäre Carnieri, Priscila Dabaghi-Barbosa, Andreia Mariante Rocha, Anderson Franco da Cruz Lima, Brás Heleno de Oliveira, Maria Benigna Martinelli de Oliveira, Eva Gunilla Skäre Carnieri, Sílvia Maria Suter Correia Cadena, Priscila Dabaghi-Barbosa, Andreia Mariante Rocha, Anderson Franco da Cruz Lima, Brás Heleno de Oliveira, Maria Benigna Martinelli de Oliveira, Eva Gunilla Skäre Carnieri, Sílvia Maria Suter Correia Cadena, Maria Eliane Merlin Rocha, Priscila Dabaghi-Barbosa, Andreia Mariante Rocha, Anderson Franco da Cruz Lima, Brás Heleno de Oliveira, Maria Benigna Martinelli de Oliveira, Eva Gunilla Skäre Carnieri, Sílvia Maria Suter Correia Cadena, Maria Eliane Merlin Rocha,

Hispidulin (6-methoxy-5,7,4′-trihydroxyflavone) and eupafolin (6-methoxy-5,7,3′,4′-tetrahydroxyflavone), are flavonoids found in the leaves of Eupatorium litoralle. They have recognized antioxidant and antineoplastic properties, although their action mechanisms have not been previously described. We now report the effects of hispidulin on the oxidative metabolism of isolated rat liver mitochondria (Mit) and have also investigated the prooxidant and antioxidant capacity of both flavonoids. Hispidulin ( ...

Tópico(s): Genomics, phytochemicals, and oxidative stress

2005 - Taylor & Francis | Free Radical Research

Artigo Revisado por pares

G. M. Besana-Ostman, Susana Vilanova, Eliza Nemser, Ana Paula Falcão, Sandra Heleno, H. Ferreira, J. F. B. D. Fonseca,

... by this author on: GSW Google Scholar S. Heleno; S. Heleno Institute for Structures, Engineering, Territory and Construction (ICIST) ... ist.utl.pt (G. M. B.-O.) S. Heleno 1Institute for Structures, Engineering, Territory and Construction (ICIST), ... Vilanova, E. S. Nemser, A. Falcao-Flor, S. Heleno, H. Ferreira, J. D. Fonseca; Large Holocene Earthquakes ...

Tópico(s): Geological and Geochemical Analysis

2012 - Seismological Society of America | Seismological Research Letters

Artigo Revisado por pares

T. B. Mitford,

... intention to devote a special study to the Helenos who governed Cyprus for the Ptolemies (as I ... temple at Old Paphos two new dedications of Helenos himself (our nos. 1 and 4 below); while ... These compel me not merely to ascribe to Helenos both a text which I have wrongly restored ( ... be my final reconstruction of the career of Helenos. Some fresh light will be thrown in the ...

Tópico(s): Classical Antiquity Studies

1959 - Cambridge University Press | The Journal of Hellenic Studies

Revisão Acesso aberto Revisado por pares

Manuel Nogales, Rúben Heleno, Anna Traveset, Pablo Vargas,

... seeds as the most important local seed dispersers (Heleno et al., 2011). So far, it is still ...

Tópico(s): Plant and animal studies

2012 - Wiley | New Phytologist

Artigo

Grégor Marchand,

... partir de 1955 sous la direction de M. Heleno, sans jamais etre publies. Des niveaux de ces ...

Tópico(s): Archaeological and Historical Studies

2001 - | Revista portuguesa de arqueologia

Artigo Acesso aberto Revisado por pares

G. Baur,

... 978-3-319-34052-4_4Susana Chamorro, Ruben Heleno, Jens M. Olesen, Conley K. McMullen, Anna Traveset ... 1501.https://doi.org/10.1093/aob/mcs132Ruben HELENO, Stephen BLAKE, Patricia JARAMILLO, Anna TRAVESET, Pablo VARGAS, ...

Tópico(s): Botany and Geology in Latin America and Caribbean

1891 - University of Chicago Press | The American Naturalist

Artigo Acesso aberto Brasil Produção Nacional

Carlos Roberto da Silveira, Márcia Aparecida Amador Mascia, Luciana Aparecida Silva de Azeredo,

... que momento Asclépio se tornou importante para os helenos? Qual a simbólica do galo para os atenienses? ... qué momento Asclepio se hizo importante para los helenos? ¿Cuál es la simbología del gallo para los ...

Tópico(s): Brazilian cultural history and politics

2021 - | EDUCAÇÃO E FILOSOFIA

Artigo Acesso aberto Brasil Produção Nacional Revisado por pares

Gustavo Cerqueira Guimarães,

Resenha de Nunca houve um homem como Heleno, de Marcos Eduardo Neves.

Tópico(s): Literature, Culture, and Criticism

2012 - UNIVERSIDADE FEDERAL DE MINAS GERAIS | Aletria Revista de Estudos de Literatura

Artigo Brasil Produção Nacional Revisado por pares

Daiane Cristina Sass, Vladimir Constantino Gomes Heleno, Simone Cavalcante, Jader da Silva Barbosa, Ana Carolina Ferreira Soares, Maurício Gomes Constantino,

... Stryker's ReagentDaiane Cristina Sass†, Vladimir Constantino Gomes Heleno‡, Simone Cavalcante†, Jader da Silva Barbosa†, Ana Carolina ...

Tópico(s): Chemistry Education and Research

2012 - American Chemical Society | The Journal of Organic Chemistry

Artigo Acesso aberto Revisado por pares

Izamara de Oliveira, Antonios Chrysargyris, Tiane C. Finimundy, Márcio Carocho, Celestino Santos‐Buelga, Ricardo C. Calhelha, Nikolaos Tzortzakis, Lillian Barros, Sandrina A. Heleno,

Pansy and viola edible flowers were grown hydroponically with different levels of Mg and Mn. The nutritional composition was determined using standard methods. Free sugars, fatty acids, organic acids, tocopherols, and phenolic compounds were analyzed using various HPLC and GC devises. The extract's antimicrobial, antioxidant, cytotoxicity, and anti-inflammatory activity were assessed. The results indicated that Mg enrichment negatively affected plant growth and mineral accumulation but improved ...

Tópico(s): Phytochemicals and Antioxidant Activities

2023 - Elsevier BV | Food Chemistry

Artigo Brasil Produção Nacional Revisado por pares

Marcelo Paradiso Marinovic, Celso Pereira Batista Sousa-Filho, Fernanda Aparecida Heleno Batista, Thayná Mendonça Avelino, Bruno Cogliati, Ana Carolina Migliorini Figueira, Rosemari Otton, Alice Cristina Rodrigues,

We postulated that Green tea (GT) improvements in non-alcoholic fatty liver disease (NAFLD) are dependent on adiponectin action in the liver. Male wild-type and adiponectin knockout (adipoKO) mice were induced to obesity for 8 weeks with a high-fat diet and then treated with GT for the last 12 weeks of the experimental protocol. Glucose and insulin tolerance tests, indirect calorimetry, histologic analysis of liver sections, and quantification of mRNA of hepatic genes related to glucose or fatty acid ...

Tópico(s): Liver Disease Diagnosis and Treatment

2022 - Elsevier BV | The Journal of Nutritional Biochemistry

Artigo Acesso aberto Revisado por pares

Marco Wirtz, Miguel Heleno, Alexandre Moreira, Thomas Schreiber, Dirk Müller,

The adequate planning of district energy systems is a key process to provide communities with proper heating and cooling networks. To find cost-effective planning solutions, this decision-making process is usually formulated as mathematical model, which is optimized to determine where and how many assets should be installed in the network. However, this optimization problem is becoming more complex as district energy systems evolve and become more elaborate. For the 5th generation district heating ...

Tópico(s): Spacecraft and Cryogenic Technologies

2022 - Elsevier BV | Energy Conversion and Management

Artigo Acesso aberto Revisado por pares

Filipa A. Fernandes, Sandrina A. Heleno, José Pinela, Márcio Carocho, Miguel A. Prieto, Isabel C.F.R. Ferreira, Lillian Barros,

The production of citrus juice generates a large quantity of by-products, which are often discarded or used for animal feed. However, several studies have shown its richness in valuable compounds, namely organic acids. Thus, this work intended to valorize orange and lime peels as renewable sources of citric acid. An experimental design combining five levels of the independent variables time (2–45 min), ultrasonic power (50–500 W), and ethanol proportion (0–100%) was implemented and response surface ...

Tópico(s): Botanical Research and Applications

2022 - Multidisciplinary Digital Publishing Institute | Chemosensors

Artigo Acesso aberto Brasil Produção Nacional Revisado por pares

Lucas Pereira Martins, Daniel B. Stouffer, Pedro G. Blendinger, Katrin Böhning‐Gaese, Galo Buitrón‐Jurado, Marta Correia, José Miguel Costa, D. Matthias Dehling, Camila I. Donatti, Carine Emer, Mauro Galetti, Rúben Heleno, Pedro Jordano, Ícaro Menezes, José Carlos Morante‐Filho, Marcia C. Muñoz, Eike Lena Neuschulz, Marco A. Pizo, Marta Quitián, Román A. Ruggera, Francisco Saavedra, Vinicio Santillán, Virginia Sanz D’Angelo, Matthias Schleuning, Luís P. da Silva, Fernanda Ribeiro da Silva, Sérgio Timóteo, Anna Traveset, Maximilian G. R. Vollstädt, Jason M. Tylianakis,

Abstract Species interactions can propagate disturbances across space via direct and indirect effects, potentially connecting species at a global scale. However, ecological and biogeographic boundaries may mitigate this spread by demarcating the limits of ecological networks. We tested whether large-scale ecological boundaries (ecoregions and biomes) and human disturbance gradients increase dissimilarity among plant-frugivore networks, while accounting for background spatial and elevational gradients ...

Tópico(s): Animal Ecology and Behavior Studies

2022 - Nature Portfolio | Nature Communications

Revisão Brasil Produção Nacional Revisado por pares

Natália Lima Lira, Sandro Tonello, Roberto Laridondo Lui, Josiane Baccarin Traldi, Heleno Brandão, Cláudio Oliveira, Daniel Rodrigues Blanco,

Tópico(s): Fish Ecology and Management Studies

2022 - Springer Nature | Molecular Biology Reports

Artigo Acesso aberto Revisado por pares

Beatriz de la Fuente, José Pinela, Filipa Mandim, Sandrina A. Heleno, Isabel C.F.R. Ferreira, Francisco J. Barba, Houda Berrada, Cristina Caleja, Lillian Barros,

The efficiency of the microwave-assisted extraction (MAE) technique on recovering nutritional and bioactive oils from salmon (Salmo salar) side streams was evaluated and compared to Soxhlet extraction. The response surface methodology (RSM) coupled with a central composite rotatable design was used to optimize time, microwave power, and solid/liquid ratio of the MAE process in terms of oil yield. The optimal MAE conditions were 14.6 min, 291.9 W, 80.1 g/L for backbones, 10.8 min, 50.0 W, 80.0 g/L for ...

Tópico(s): Antioxidant Activity and Oxidative Stress

2022 - Elsevier BV | Food Chemistry

Artigo Acesso aberto Brasil Produção Nacional Revisado por pares

Gibson Moreira Praça, Mauro Heleno Chagas, Sarah da Glória Teles Bredt, André Gustavo Pereira de Andrade,

This study aimed to systematically review the influence of the relative area on athletes' physical and physiological responses (outcomes) during small-sided games of soccer which were not matched to the relative area. It also presents a meta-analysis comparing standard small-sided games protocols with different relative areas. We searched the Web of Science and Scopus electronic databases for literature published up to March 2020 following all PRISMA guidelines for selecting articles for a qualitative ...

Tópico(s): Sports injuries and prevention

2022 - De Gruyter Open | Journal of Human Kinetics

Artigo Acesso aberto Revisado por pares

Nabila Ben Derbassi, Mariana C. Pedrosa, Sandrina A. Heleno, Márcio Carocho, Isabel C.F.R. Ferreira, Lillian Barros,

Secondary metabolism of plants produces molecules that are widely used in the food industry for many years. The demand for these molecules has been increasing, and special focus has been given to volatile molecules. The study of secondary metabolites with special focus on the volatile molecules is overviewed, explaining their bioactivities and examples of application in the food industry. Systematic analysis of volatiles and their applications. Specific analysis of volatile components of plants ...

Tópico(s): Allelopathy and phytotoxic interactions

2022 - Elsevier BV | Trends in Food Science & Technology

Artigo Acesso aberto Revisado por pares

Miguel Heleno, Ben Sigrin, Natalie Popovich, Jenny Heeter, Anjuli Jain Figueroa, Michael Reiner, Tony G. Reames,

This paper presents a quantitative framework to support policy decision-making around equitable energy interventions. By combining sociodemographic and techno-economic models in the energy space, we propose a linear programming model to calculate the optimal portfolio of energy investments that explicitly minimizes the energy burden of a given population of energy insecure households. The model is formulated as a multi-objective optimization suitable to support the decisions on weatherization and ...

Tópico(s): Building Energy and Comfort Optimization

2022 - Elsevier BV | Applied Energy

Artigo Acesso aberto

José Ignacio Alonso‐Esteban, Márcio Carocho, Diana Barros, Manuela Vaz‐Velho, Sandrina A. Heleno, Lillian Barros,

Maritime pine (Pinus pinaster Ait.) is native to the western Mediterranean basin and has an economic importance in southwestern Europe. This importance is based on the use of its wood in the construction, furniture, and paper industries. Bark and other parts of the plant, such as resin, needles, and cones, are by-products with potential industrial application. These parts of the tree stand out because of the presence of secondary metabolites, the main ones being phenolic compounds and terpenes. Bark ...

Tópico(s): Plant-Derived Bioactive Compounds

2022 - Springer Science+Business Media | Reviews in Environmental Science and Bio/Technology

Artigo Revisado por pares

Alessandra Durazzo, Márcio Carocho, Sandrina A. Heleno, Lillian Barros, Eliana B. Souto, Antonello Santini, Massimo Lucarini,

Food color is often associated in the collective imagination to properties like flavor, taste, sensory qualities, and genuinity. While synthetic food dyes may cause several harmful effects to human health, and most of them are not used or allowed in food manufacturing according to the regulations of each country, the origin of food dyes are receiving greater attention for their safety, hence being more present in literature studies. This perspective aims at providing a current framework on food ...

Tópico(s): Medicinal Plants and Neuroprotection

2022 - Elsevier BV | Measurement Food

Artigo Acesso aberto Brasil Produção Nacional Revisado por pares

Sérgio Timóteo, Jörg Albrecht, Beatriz Rumeu, Ana Cláudia Norte, Anna Traveset, Carol M. Frost, Elizabete Marchante, Francisco A. López‐Núñez, Guadalupe Peralta, Jane Memmott, Jens M. Olesen, José Miguel Costa, Luís P. da Silva, Luísa G. Carvalheiro, Marta Correia, Michael Staab, Nico Blüthgen, Nina Farwig, Sandra Hervías‐Parejo, Sergey V. Mironov, Susana Rodríguez‐Echeverría, Rúben Heleno,

Abstract Keystone species are disproportionately important for ecosystem functioning. While all species engage in multiple interaction types with other species, keystone species importance is often defined based on a single dimension of their Eltonian niche, that is, one type of interaction (e.g. keystone predator). It remains unclear whether the importance of keystone species is unidimensional or if it extends across interaction types. We conducted a meta‐analysis of tripartite interaction networks ...

Tópico(s): Species Distribution and Climate Change

2022 - Wiley | Functional Ecology

Artigo Acesso aberto Revisado por pares

Ana María, Helena Serra, Bruno Heleno,

Digitization in everyday medical practice has gained importance along with the drive to expand teleconsultations arising from the COVID-19 pandemic. Previous qualitative research on teleconsultations has focused on synchronous communication between patients and clinicians. This study aims to explore physicians' and patients' perspectives on the adoption of teleconsultations between primary care and the referral cardiology department.

Tópico(s): Patient Satisfaction in Healthcare

2022 - Elsevier BV | International Journal of Medical Informatics

Artigo Acesso aberto Brasil Produção Nacional Revisado por pares

Gustavo Fernando Mercaldi, Eduardo Henrique Salviano Bezerra, Fernanda Aparecida Heleno Batista, C.C.C. Tonoli, Adriana Santos Soprano, Jacqueline Farinha Shimizu, Alice Nagai, Jaqueline Cristina da Silva, Helder Veras Ribeiro Filho, Jéssica do Nascimento Faria, Marcos Guilherme da Cunha, Ana Zeri, Andrey Fabricio Ziem Nascimento, José Luiz Proença‐Módena, Marcio C. Bajgelman, Silvana A. Rocco, Paulo Sérgio Lopes de Oliveira, Artur T. Cordeiro, Marjorie Bruder, Rafael Elias Marques, Maurício L. Sforça, Kleber G. Franchini, Celso Eduardo Benedetti, Ana Carolina Migliorini Figueira, Daniela Barretto Barbosa Trivella,

Abstract The nucleocapsid (N) protein plays critical roles in coronavirus genome transcription and packaging, representing a key target for the development of novel antivirals, and for which structural information on ligand binding is scarce. We used a novel fluorescence polarization assay to identify small molecules that disrupt the binding of the N protein to a target RNA derived from the SARS-CoV-2 genome packaging signal. Several phenolic compounds, including L-chicoric acid (CA), were identified ...

Tópico(s): thermodynamics and calorimetric analyses

2022 - Nature Portfolio | Scientific Reports

Revisão Acesso aberto Revisado por pares

Jonata M. Ueda, Mariana C. Pedrosa, Sandrina A. Heleno, Márcio Carocho, Isabel C.F.R. Ferreira, Lillian Barros,

Food waste is one of the fundamental issues when it comes to environmental impacts, and this type of waste results in the food’s loss itself, but also that of water, energy, fertilizers, and other resources used for its production. Many vegetable parts are removed from the final product before reaching retail (peels, roots, and seeds), and these raw materials are rich sources of highly valuable molecules such as phytochemicals, minerals, vitamins, and other compounds with health benefits (prevention ...

Tópico(s): Consumer Attitudes and Food Labeling

2022 - Multidisciplinary Digital Publishing Institute | Sustainability

Artigo Acesso aberto Brasil Produção Nacional Revisado por pares

Helder Veras Ribeiro Filho, Gabriel Ernesto Jara, Fernanda Aparecida Heleno Batista, Gabriel R. Schleder, C.C.C. Tonoli, Adriana Santos Soprano, Samuel Leite Guimarães, Antônio Carlos Borges, Alexandre Cassago, Marcio C. Bajgelman, Rafael Elias Marques, Daniela Barretto Barbosa Trivella, Kleber G. Franchini, Ana Carolina Migliorini Figueira, Celso Eduardo Benedetti, Paulo Sérgio Lopes de Oliveira,

The nucleocapsid (N) protein of the SARS-CoV-2 virus, the causal agent of COVID-19, is a multifunction phosphoprotein that plays critical roles in the virus life cycle, including transcription and packaging of the viral RNA. To play such diverse roles, the N protein has two globular RNA-binding modules, the N- (NTD) and C-terminal (CTD) domains, which are connected by an intrinsically disordered region. Despite the wealth of structural data available for the isolated NTD and CTD, how these domains ...

Tópico(s): Bacteriophages and microbial interactions

2022 - Public Library of Science | PLoS Computational Biology

Artigo Acesso aberto

Vicente G. Cancho, Edwin M. M. Ortega, Heleno Bolfarine,

In this paper the log-exponentiated-Weibull regression model is modified to allow the possibility that long term survivors are present in the data. The modification leads to a log-exponentiated-Weibull regression model with cure rate, encompassing as special cases the log-exponencial regression and log-Weibull regression models with cure rate typically used to model such data. The models attempt to estimate simultaneously the effects of covariates on the acceleration/deceleration of the timing of ...

Tópico(s): Statistical Methods and Inference

2021 - People's University of China | Journal of Data Science

Artigo Acesso aberto Revisado por pares

Custódio Lobo Roriz, Sandrina A. Heleno, Maria José Alves, M. Beatriz P.P. Oliveira, José Pinela, María Inês Días, Ricardo C. Calhelha, Patrícia Morales, Isabel C.F.R. Ferreira, Lillian Barros,

Hylocereus costaricensis peel contains large amounts of betacyanins and can be exploited as a source of natural colorants. This work aimed the chemical characterization and evaluation of bioactive properties of this by-product and the optimization of the ultrasound-assisted extraction (UAE) of betacyanins using the response surface methodology (RSM). Oxalic and malic acids and traces of fumaric acid were detected, as well as the four tocopherol isoforms, predominantly γ-tocopherol. Four betacyanins ...

Tópico(s): Botanical Research and Applications

2021 - Elsevier BV | Food Chemistry

Artigo Brasil Produção Nacional Revisado por pares

R. Heleno, P.A. Montenegro, Hermes Carvalho, Diogo Ribeiro, Rui Calçada, Chris Baker,

The aim of the present study consists of evaluating the influence of the most relevant geometric, mechanical and aerodynamic vehicle properties in the risk of derailment caused by crosswinds. To achieve this objective, a vehicle-structure interaction model is used to carry out non-linear dynamic analyses to assess the train-track coupling behaviour in the presence of winds. By computing the wheel-rail contact forces, the derailment risk is evaluated based on the unloading criterion, as suggested ...

Tópico(s): Fluid Dynamics and Vibration Analysis

2021 - Elsevier BV | Journal of Wind Engineering and Industrial Aerodynamics

Artigo Acesso aberto Revisado por pares

Juan Antonio,

Este artículo procura contribuir a la destrucción de la visión helenocéntrica y eurocéntrica de la historia universal que ha excluido a América Latina de la Antigüedad, la filosofía, la política, la educación y la religión. Así mismo, reforzaremos la tesis de que el origen de la filosofía griega es egipcia, y además es negra. F. Hegel piensa que la historia del espíritu absoluto viene de Oriente a Occidente, el centro es Europa, elimina a África de la historia y América (del Norte) es una posibilidad. ...

Tópico(s): History and Politics in Latin America

2021 - Universidad del Norte, Colombia | Memorias