Srikumar Sen, Boxing Correspondent, Victoria McKee, Frances Gibb, Legal Affairs Correspondent, David Tytler, Nicholas Wood, Political Correspondent, Thomson Prentice Medical Correspondent, Christopher Warman, Property Correspondent, Barbara Lamb, Jasper Rees, Tim Judah, Mark Souster, Geraldine Bedell, Andrew Warren, Director, K. Beere, Michael Horsnell and Ian Murray, S. M. Cretney, Zahid Hussein, Angela MacKay, H. Elwyn Jones, Philip Howard, Sally Brompton, Jeremy Kingston, Clive Davis, Carol Leonard, Louis Muinzer, Albert Dormer, Stuart Jones Football Correspondent, Simon Wilde, Joe Joseph, Martin Fletcher, Mitchell Platts, Golf Correspondent, Bruce Clark, David Hanney, Allen Carter, Norman Hammond, Archaeology Correspondent, Peter Ball, Louise Taylor, Alexandra King, Martin Barrow, Alan Hamilton, Robin Young, Nicholas Watt, Michael McCarthy, Environment Correspondent, Michael Clark, Philip Robinson, David Pearce, Alexei I. Tsiurupa Deputy Chairman, Tom Burke, Denis Vaughan, David Hands, Charles Bremner, Joseph Connolly, Quentin Cowdry Home Affairs Correspondent, Jane Wyatt, Sally Jones, George Rae, H. S. Eisner (Editor), Neil Kelly, Sydney Friskin, Dennis Signy, David Miller, Robin Oakley Political Editor, Gillian Bowditch, Marthin Jacques, Kerry Gill, Jonathan Prynn, David Brewerton Executive Editor, Robert Worcester, Nicholas Beeston, Raymond Keene, Chess Correspondent, Craig Brown, Paul Wilkinson, Steve Acteson, Peter Bryan, Richard Evans, Michael Wright, Craig Seton, M. G. Al-Rumaihi, Chairman, Dan White, Barry Pickthall, Brian Beel, Michael Hornsby, Agriculture Correspondent, David Hands Rugby Correspondent, David Brewerton, Richard Duce, Christopher Warman Property Correspondent, John Goodbody, Michael Gray, Colin Narbrough, Economics Correspondent, Mel Webb, Clive White, Michael Seely, Andrew Duncan, Owen Jenkins, Michael Austin, Brian Buchanan, Thomson Prentice, Medical Correspondent, Brian Roycroft (Director of Social Services), Peter Victor, Michael Knipe, Diplomatic Correspondent, John Lewis, Philip Pangalos, George Chesterton, Benedict Nightingale, Michael Charlesworth, Richard Morrison, Anne McElvoy, Michael Evans, Robin E. Gurney Secretary, Matthew Bond, Jan Raath, Philip Jacobson,
... Campaign to compensate victims of child abuse (US): Larsen the leader Jet falls 30,000ft Medal stolen ... festival devoted to the work of Norwegian playwright Henrik Ibsen, as Louis Muinzer reports Times Atlases Theatre ...
1990 - Gale Group | TDA
Claus Scheuer-Larsen, Henrik M. Pfundheller, Jesper Wengel,
... into a Novel Class of Nucleoside AnalogsClaus Scheuer-Larsen, Henrik M. Pfundheller, and Jesper WengelCite this: J. Org. ...
Tópico(s): HIV/AIDS drug development and treatment
1995 - American Chemical Society | The Journal of Organic Chemistry
... org/10.1002/job.2160Morten Frederiksen, Christian A Larsen, Henrik L Lolle Education and trust, Acta Sociologica 59, ...
Tópico(s): Privacy, Security, and Data Protection
1996 - University of Chicago Press | Ethics
Peter Nystrup, Bo William Hansen, Henrik Olejasz Larsen, Henrik Madsen, Erik Lindström,
This article investigates whether regime-based asset allocation can effectively respond to changes in financial regimes at the portfolio level in an effort to provide better long-term results when compared to a static 60/40 benchmark. The potential benefit from taking large positions in a few assets at a time comes at the cost of reduced diversification. The authors analyze this trade-off in a multi-asset universe with great potential for static diversification. The regime-based approach is centered ...
Tópico(s): Complex Systems and Time Series Analysis
2017 - Euromoney Institutional Investor | The Journal of Portfolio Management
Reimar W. Thomsen, Marie Germund Nielsen, Mette Nørgaard, Henriette Thisted Horsdal, Til Stürmer, Finn Breinholt Larsen, Henrik Toft Sørensen,
... of North Carolina Chapel Hill, NC Finn Breinholt Larsen Public Health and Quality Improvement Central Denmark Region Aarhus, Denmark Henrik Toft Sørensen Department of Clinical Epidemiology Institute of ...
Tópico(s): Pharmaceutical Economics and Policy
2013 - Lippincott Williams & Wilkins | Epidemiology
Caroline Schmidt Laugesen, Christoffer Ostri, Troels Brynskov, Henrik Lund‐Andersen, Michael Larsen, Henrik Vorum, Torben Lykke Sørensen,
There is little information about the efficacy of intravitreal vascular endothelial growth factor (VEGF) inhibition in vitrectomized eyes. This study aimed to evaluate the efficacy of anti-VEGF (ranibizumab) on diabetic macular oedema in previously vitrectomized eyes.A nationwide retrospective review of medical records from 2010 to 2013.We identified 33 previously vitrectomized eyes in 28 patients treated with ranibizumab injections for diabetic macular oedema. Median follow-up was 323 days (interquartile ...
Tópico(s): Retinal Imaging and Analysis
2016 - Wiley | Acta Ophthalmologica
... Nordic States, London: Routledge, 2002. 8. Nina Græger, Henrik Larsen and Hanna Ojanen (eds), The ESDP and the ... Dimension: A "troops-for-influence" Strategy', in Græger, Henrik Larsen and Hanna Ojanen (eds.) The ESDP and the ...
Tópico(s): European Union Policy and Governance
2007 - Taylor & Francis | International Peacekeeping
Niels Hadrup, Katrin Loeschner, Anders Bergström, Andrea Wilcks, Xueyun Gao, Ulla Vogel, Henrik Lauritz Frandsen, Erik H. Larsen, Henrik Rye Lam, Alicja Mortensen,
Tópico(s): Trace Elements in Health
2011 - Springer Science+Business Media | Archives of Toxicology
Efstathios Vassiliadis, Sanne Skovgård Veidal, Natasha Barascuk, Jhinuk Basu Mullick, Rikke Elgaard Clausen, Lise Larsen, Henrik Toft Simonsen, Dorthe Vang Larsen, Anne‐Christine Bay‐Jensen, Toni Segovia‐Silvestre, Diana Julie Leeming, M.A. Karsdal,
The current study utilized a Bleomycin-induced model of skin fibrosis to investigate the neo-epitope CO3-610 (KNGETGPQGP), a fragment of collagen III released during matrix metalloproteinase-9 (MMP9) degradation of the protein, we have previously described as a novel biomarker for liver fibrosis. The aim was to investigate CO3-610 levels in another well characterised model of fibrosis, to better describe the biomarker in relation to additional fibrotic pathologies.Skin fibrosis was induced by daily ...
Tópico(s): Wnt/β-catenin signaling in development and cancer
2011 - Springer Science+Business Media | BMC Dermatology
Niels Hadrup, Katrin Loeschner, Karen Mandrup, Gitte Ravn‐Haren, Henrik Lauritz Frandsen, Erik H. Larsen, Henrik Rye Lam, Alicja Mortensen,
Selenium (Se) nanoparticles have been proposed as food supplements. However, the particle formulation may exert unexpected toxicity. The aim was therefore to compare toxicity of low doses of Se nanoparticles and the dissolved, ionized Se species selenite. Female rats were dosed orally for 28 d with either: 0.05, 0.5, or 4 mg Se/kg body weight (bw)/day as 20 nm Se nanoparticles or 0.05 or 0.5 mg Se/kg bw/day as sodium selenite. Male rats were dosed 4 mg Se/kg bw/day as Se nanoparticles. Body weight ...
Tópico(s): Trace Elements in Health
2018 - Taylor & Francis | Drug and Chemical Toxicology
Henrik Larsen, Jens Benn Sørensen,
... adjuvant chemotherapy of pulmonary blastoma: A case report Henrik Larsen M.D., Corresponding Author Henrik Larsen M.D. Department of Oncology Finsen Center, National ... Copenhagen, DenmarkSearch for more papers by this author Henrik Larsen M.D., Corresponding Author Henrik Larsen M.D. Department of Oncology Finsen Center, National ...
Tópico(s): Medical Imaging and Pathology Studies
1996 - Wiley | Cancer
C. Engler, Hans‐Henrik Parving, Elisabeth R. Mathiesen, Michael Larsen, Henrik Lund‐Andersen,
Abstract We assessed the acute effect of ACE‐inhibition (captopril) on blood‐retina barrier (BRB) permeability in 10 hypertensive insulin‐dependent diabetic patients with background retinopathy in a double‐masked placebo controlled cross‐over study. All patients underwent ophthalmological examination, fundus photography, fluorescein angiography, vitreous fluorometry, and continuous blood pressure recording within 3 h of the drug/placebo administration. The decrease in mean arterial blood presure, ...
Tópico(s): Blood Pressure and Hypertension Studies
1991 - Wiley | Acta Ophthalmologica
Karin Groenbæk, Henrik Friis, Max Hansen, Helmer Ring‐Larsen, Henrik Krarup,
To assess the effect of antioxidant supplementation on hepatitis C viral load, transaminases and oxidative status.We performed a randomized, placebo-controlled, double-blind trial to assess the effect of antioxidant supplementation on serum alanine aminotransferase, plasma hepatitis C viral load as well as oxidative and antioxidant markers in patients with hepatitis C virus infection. The participants received a daily dose of ascorbic acid (500 mg), D-alpha-tocopherol (945 IU) and selenium (200 microg) ...
Tópico(s): Drug-Induced Hepatotoxicity and Protection
2006 - Lippincott Williams & Wilkins | European Journal of Gastroenterology & Hepatology
Frederik Bock, Eva Lin, Claus Larsen, Henrik Jensen, Kasper Huus, Susan Weng Larsen, Jesper Østergaard,
Therapeutic proteins and peptides are mainly administrated by subcutaneous injection. In vitro release testing of subcutaneous injectables performed using methods that take the structure and environment of the subcutaneous tissue into account may improve predictability of the in vivo behavior and thereby facilitate establishment of in vitro in vivo correlations. The aim of the study was to develop a biopredictive flow-through in vitro release method with a gel-type matrix for subcutaneously administered ...
Tópico(s): Advancements in Transdermal Drug Delivery
2020 - Elsevier BV | European Journal of Pharmaceutical Sciences
Troels Haxholdt Lunn, B. Kristensen, Lasse Andersen, Henrik Husted, Kristian Stahl Otte, Lissi Gaarn-Larsen, Henrik Kehlet,
BackgroundTotal knee arthroplasty (TKA) is associated with severe pain and inflammation despite an extensive multimodal analgesic approach, but the effect of high-dose glucocorticoid administration has not been studied.MethodsForty-eight patients undergoing unilateral TKA were included in a randomized, double-blind, placebo-controlled trial receiving preoperative methylprednisolone (MP) 125 mg i.v. or saline. All surgery was performed under lumbar spinal anaesthesia and patients received a standardized, ...
Tópico(s): Pain Management and Opioid Use
2010 - Elsevier BV | British Journal of Anaesthesia
Lasse Andersen, Henrik Husted, B. Kristensen, Kristian Stahl Otte, Lissi Gaarn-Larsen, Henrik Kehlet,
The optimal site for wound delivery of local anaesthetic after total knee arthroplasty is undetermined. Sixty patients having total knee arthroplasty received intra-operative infiltration analgesia with ropivacaine 0.2% and were then were randomly assigned to receive either intracapsular or intra-articular catheters with 20 ml ropivacaine 0.5% given at 6 h and again at 24 h, postoperatively. Analgesic efficacy was assessed for 3 h after each injection, using a visual analogue score, where 0 = no pain ...
Tópico(s): Total Knee Arthroplasty Outcomes
2010 - Wiley | Anaesthesia
Lasse Andersen, Henrik Husted, B. Kristensen, Kristian Stahl Otte, Lissi Gaarn-Larsen, Henrik Kehlet,
High-volume wound local infiltration analgesia is effective in knee arthroplasty, but the analgesic efficacy of subcutaneous wound infiltration has not been evaluated.In a randomised, double-blind, placebo-controlled trial in 16 patients undergoing bilateral knee arthroplasty with high-volume local infiltration analgesia in the deeper layers, saline or ropivacaine 2 mg/ml was infiltrated into the subcutaneous part of the wound in each knee along with the placement of multi-fenestrated catheters ...
Tópico(s): Shoulder Injury and Treatment
2010 - Wiley | Acta Anaesthesiologica Scandinavica
Niels Hadrup, Henrik Rye Lam, Katrin Loeschner, Alicja Mortensen, Erik H. Larsen, Henrik Lauritz Frandsen,
ABSTRACT Metabolomic investigation of rat urine was employed to identify mammalian metabolites affected by ionic or nanoparticulate silver. Female and male Wistar rats were administered silver nanoparticles (2.25, 4.5 or 9.0 mg kg −1 body weight per day) or ionic silver (silver acetate, 9.0 mg silver kg −1 bw per day) by oral gavage for 28 days. On day 18, urine was collected for 24 h and subjected to metabolomics with high performance liquid chromatography–quadropole time‐of‐flight mass spectrometry ( ...
Tópico(s): Vitamin C and Antioxidants Research
2012 - Wiley | Journal of Applied Toxicology
Peter Larsen, Henrik Bangsø Nielsen, Christoffer Lund, Daniel S. Sørensen, Birgit Tine Larsen, Mark Matthews, Bill Vicenzino, Rasmus Elsøe,
Assessment of ankle joint movement in a weight bearing position has important clinical implications. The lunge ankle dorsiflexion measurement device (LAD) has been developed with the aim of facilitating ease of and standardisation of the measurement of ankle joint movement. The literature lacks studies evaluating the reliability of weight bearing measurements of the ankle joint in study groups with ankle disabilities. The objective of this study was to examine the intra- and inter-tester reliability ...
Tópico(s): Orthopedic Surgery and Rehabilitation
2016 - Elsevier BV | Foot and Ankle Surgery
Axel Diederichsen, Niels Peter Rønnow Sand, Bjarne Linde Nørgaard, Jess Lambrechtsen, Jesper Møller Jensen, Henrik Munkholm, Ahmed Abdel Aziz, Oke Gerke, Kenneth Egstrup, Mogens Lytken Larsen, Henrik Petersen, Poul Flemming Høilund‐Carlsen, Hans Mickley,
Background: Coronary artery calcification (CAC) is an independent and incremental risk marker. This marker has previously not been compared to the HeartScore risk model. Design: A random sample of 1825 citizens (men and women, 50 or 60 years of age) was invited for screening. Methods: Using the HeartScore model, the 10-year risk of fatal cardiovascular events based on gender, age, smoking, systolic blood pressure, and total cholesterol was estimated. A low risk was defined as <5%. The CAC score was ...
Tópico(s): Acute Myocardial Infarction Research
2011 - Oxford University Press | European Journal of Preventive Cardiology
Grit Elster Legaard, Camilla S. Feineis, Mette Y. Johansen, Katrine Bagge Hansen, Allan Vaag, Emil List Larsen, Henrik E. Poulsen, Thomas Almdal, Kristian Karstoft, Bente Klarlund Pedersen, Mathias Ried‐Larsen,
This secondary analysis aimed to investigate the effects of a 12 months intensive exercise-based lifestyle intervention on systemic markers of oxidative stress in persons with type 2 diabetes. We hypothesized lifestyle intervention to be superior to standard care in decreasing levels of oxidative stress. The study was based on the single-centre, assessor-blinded, randomised, controlled U-turn trial (ClinicalTrial.gov NCT02417012). Persons with type 2 diabetes ˂ 10 years, ˂ 3 glucose lowering medications, ...
Tópico(s): Diet and metabolism studies
2022 - Elsevier BV | Free Radical Biology and Medicine
Troels Haxholdt Lunn, Henrik Husted, Søren Solgaard, B. Kristensen, Kristian Stahl Otte, Anne Grete Kjersgaard, Lissi Gaarn-Larsen, Henrik Kehlet,
High-volume local infiltration analgesia (LIA) is widely applied as part of a multimodal pain management strategy in total hip arthroplasty (THA). However, methodological problems hinder the exact interpretation of previous trials, and the evidence for LIA in THA remains to be clarified. Therefore, we evaluated whether intraoperative high-volume LIA, in addition to a multimodal oral analgesic regimen, would further reduce acute postoperative pain after THA.Patients scheduled for unilateral, primary ...
Tópico(s): Pain Management and Opioid Use
2011 - BMJ | Regional Anesthesia & Pain Medicine
J. Thomsen, K.-I. Meistrup-Larsen, P. K. Larsen, Henrik Toft Sørensen, Niels Mygind,
The effect of peroral penicillin V (55 mg/kg/day) on acute otitis media was investigated in 149 children between the ages of one and ten years in a double-blind, placebo-controlled investigation. The parameters of the disease employed were symptom scores for earache, the use of analgetics, otoscopy, as well as tympanometry. The children were followed up for three months. Penicillin had a significant effect on pain on the second day of treatment. The acute course of the disease was satisfactory in ...
Tópico(s): Ocular Infections and Treatments
1980 - SAGE Publishing | Annals of Otology Rhinology & Laryngology
G Stafanger, Hans‐Walther Larsen, Henrik Post Hansen, K. Serensen,
The pharmacokinetics of ketoprofen were studied in 7 volunteers and in 5 patients suffering from varying degrees of renal insufficiency. All the subjects received a single oral dose (50 mg) of ketoprofen. Plasma concentrations were measured up to 24 hours after administration and urinary excretion for 2 days. Ketoprofen concentrations were determined by mass-fragmentography with a minimum level of detection of 0.02 mg/1. As expected, a reduction of the [51Cr]EDTA clearance was correlated with an increase ...
Tópico(s): Antibiotics Pharmacokinetics and Efficacy
1981 - Taylor & Francis | Scandinavian Journal of Rheumatology
K.-I. Meistrup-Larsen, Henrik Toft Sørensen, N. J. Johnsen, J. Thomsen, Niels Mygind, J Sederberg-Olsen,
103 children between 1 and 10 years of age participated in a double-blind placebo-controlled trial testing the effect of penicillin-V, 55 mg/kg/day, for two days versus seven days in acute otitis media. No significant differences could be demonstrated with regard to earache, healing of the tympanic membrane, tympanometry, fever or common cold symptoms. 76% in the group treated for seven days had a satisfactory course of the disease, compared to 71 % in the group treated for two days (p>0.1). In spite ...
Tópico(s): Streptococcal Infections and Treatments
1983 - Taylor & Francis | Acta Oto-Laryngologica
Jesper Larsen, Henrik Lund‐Andersen, Bent Krogsaa,
Tópico(s): Protein Interaction Studies and Fluorescence Analysis
1983 - Springer Science+Business Media | Bulletin of Mathematical Biology
John Larsen, Henrik Lund‐Andersen, Bent Krogsaa,
Tópico(s): Drug Transport and Resistance Mechanisms
1983 - Springer Science+Business Media | Bulletin of Mathematical Biology
Bent Krogsaa, Hans C. Fledelius, Jesper Larsen, Henrik Lund‐Andersen,
Photometric oculometry is a slit‐lamp technique, which makes possible an estimation of intraocular axial distances and axial length. The technique is based on a transformation of a sagittal slit‐lamp movement into intraocular axial distances when the slit‐lamp focal plane is moved in the optical axis from retina to cornea. Determination of the axial length in 50 eyes (refractive range +4.75 to −5.25 D) showed that the axial length varied from 21.9mm in hypermetropic eyes to 26.0 mm in myopic eyes, ...
Tópico(s): Glaucoma and retinal disorders
1984 - Wiley | Acta Ophthalmologica
C. Kirkegaard, Kirsten Nørgaard, Ole Snorgaard, Toke Bek, Michael Larsen, Henrik Lund‐Andersen,
Abstract. Growth hormone is assumed to be involved in the development of diabetic retinopathy. In a randomized study we evaluated the possible effects of one year treatment with a somatostatin (SRIH) analogue, octreotide, on early retinopathy and on metabolism in Type I (insulin-dependent) diabetes mellitus. Eleven patients were allocated to treatment with a continuous sc infusion of 400 μg octreotide per day and 9 served as controls. Only 7 patients from each group completed the study. Three octreotide- ...
Tópico(s): Retinal Diseases and Treatments
1990 - Oxford University Press | European Journal of Endocrinology
R. Berger, N.W. Larsen, Henrik Svanholt, Michel Pouchard, Paul Hagenmuller, Arne F. Andresen,
Tópico(s): MXene and MAX Phase Materials
1977 - Royal Society of Chemistry | Acta chemica Scandinavica/Acta chemica Scandinavica. B, Organic chemistry and biochemistry/Acta chemica Scandinavica. A, Physical and inorganic chemistry/Acta chemica Scandinavica. Series B. Organic chemistry and biochemistry/Acta chemica Scandinavica. Series A, Physical and inorganic chemistry