Produção Nacional
Revisado por pares
Guilherme Harada, Mariane Tami Amano, F Antonácio, Marina Henkin Behar, Pedro Henrique Xavier Nabuco de Araújo, Carlos Alberto Buchpiguel, Gilberto de Castro,
Immunotherapy based on immune checkpoint inhibitors (ICIs) either alone or in combination with platinum-based chemotherapy has dramatically changed the therapeutic scenario in non-small cell lung cancer. However, only a subset of patients derives clinical benefits. Although programmed death-ligand 1 (PD-L1) and tumor mutational burden (TMB) are known to be prognostic and demonstrated utility in selecting patients for immunotherapy response, they are imperfect biomarkers. Recent evidence demonstrates ...
Tópico(s): Neuroendocrine Tumor Research Advances
2021 - Elsevier BV | Clinical Lung Cancer
Produção Nacional
Revisado por pares
Simone D. Henkin, Márcio Martins Silveira, Henrique Lannerhirt, Flávia Meyer, Luiz Fernando Martins Kruel,
Dehydration has a deleterius effect on exercise performance. Because athletes in aquatic environment have a greater opportunity to dissipate heat through conduction and convection, dehydration is seldom considered a problem in aquatic sports. PURPOSE to examine the effects of water and a sport drink intake on hematocrit concentrations, urine specific gravity (Usg) and voluntary drinking in trained acclimatized swimmers. METHODS eight boys (age 17,2 ± 3,2 years, body fat 13,6 ± 2,1%) performed two 2-h ...
Tópico(s): Thermoregulation and physiological responses
2005 - Lippincott Williams & Wilkins | Medicine & Science in Sports & Exercise
Produção Nacional
Revisado por pares
Simone D. Henkin, M rcio Martins Silveira, Henrique Lannerhirt, Fl via Meyer, Luiz Fernando Martins Kruel,
Dehydration has a deleterius effect on exercise performance. Because athletes in aquatic environment have a greater opportunity to dissipate heat through conduction and convection, dehydration is seldom considered a problem in aquatic sports. PURPOSE to examine the effects of water and a sport drink intake on hematocrit concentrations, urine specific gravity (Usg) and voluntary drinking in trained acclimatized swimmers. METHODS eight boys (age 17,2 ± 3,2 years, body fat 13,6 ± 2,1%) performed two 2-h ...
Tópico(s): Cardiovascular and exercise physiology
2005 - Lippincott Williams & Wilkins | Medicine & Science in Sports & Exercise
Kinga Kamieniarz-Gdula, Nicholas Proudfoot,
... 679-682PubMed Google Scholar, 101.Sherwood A.V. Henkin T.M. Riboswitch-mediated gene regulation: novel RNA ... 679-682PubMed Google Scholar, 101.Sherwood A.V. Henkin T.M. Riboswitch-mediated gene regulation: novel RNA ... median half-lives of paused Pol II [30.Henriques T. et al.Stable pausing by RNA polymerase ...
Tópico(s): CRISPR and Genetic Engineering
2019 - Elsevier BV | Trends in Genetics