
Carlos Henrique Corrêa dos Santos, Izabeau Pontes Borges, Virgínia Cláudia da Silva, Paulo Teixeira de Sousa, Nair Honda Kawashita, Amanda Martins Baviera, Mário Geraldo de Carvalho,
Context Siolmatra brasiliensis (Cogn.) Baill (Cucurbitaceae) is a climbing plant widely used for the treatment of diabetes mellitus symptoms.Objective This work evaluates the antidiabetic activity of an extract of S. brasiliensis in streptozotocin-diabetic rats and promotes the phytochemical investigation to isolate the major compounds of the same extract.Materials and methods Male Wistar rats were divided into normal (N) and diabetic rats (DC) treated with water; diabetic rats treated with 3U insulin ( ...
Tópico(s): Natural product bioactivities and synthesis
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