Produção Nacional
Revisado por pares
Bruna Matiuzzi Rodrigues, Henrique F.V. Victória, Guilherme Leite, Klaus Krambrock, Otávio Augusto Chaves, Diego França de Oliveira, Rafael de Q. Garcia, Leonardo De Boni, Luiz Antônio S. Costa, Bernardo A. Iglesias,
We report the synthesis and characterization of new tri-cationic corrole derivatives, containing Pt(II) or Pd(II) complexes attached at the peripheral position of thienyl moieties. Corrole derivatives were characterized through microanalysis, electrochemical, spectrometry and spectroscopy analysis. Singlet and triplet excited-states are investigated by photophysical/theoretical calculation methods and photobiological parameters were also evaluated spectroscopic techniques (UV–Vis and EPR). Also, ...
Tópico(s): Metal complexes synthesis and properties
2023 - Elsevier BV | Journal of Inorganic Biochemistry
Produção Nacional
Revisado por pares
Rafael Aparecido Carvalho Souza, Waleska R. P. Costa, Eduardo de Franca Faria, Meliza Arantes de Souza Bessa, Ralciane deP. Menezes, Carlos Henrique Gomes Martins, Pedro I. S. Maia, Victor M. Deflon, Carolina G. Oliveira,
Considering the promising previous results on the remarkable activity exhibited by cobalt(III) and manganese(II) thiosemicarbazone compounds as antibacterial agents, the present study aimed to prepare and then evaluate the antibacterial activity of two different types of Cu(II) complexes based on a 2-acetylpyridine-N(4)-methyl-thiosemicarbazone ligand (Hatc-Me), a monomer complex [CuCl(atc-Me)] and a novel dinuclear complex [{Cu(μ-atc-Me)}2μ-SO4]. The compounds were characterized by infrared spectra, ...
Tópico(s): Computational Drug Discovery Methods
2021 - Elsevier BV | Journal of Inorganic Biochemistry
Produção Nacional
... a participação dos indígenas brasileiros levados para a França em 1550 na entrada do rei Henrique II na cidade de Rouen.
Tópico(s): Literature, Culture, and Criticism
2011 - UNIVERSIDADE FEDERAL DO PARANÁ | Revista Cadernos de Clio
Produção Nacional
... a participação dos indígenas brasileiros levados para a França em 1550 na entrada do rei Henrique II na cidade de Rouen.
Tópico(s): History of Colonial Brazil
2011 - UNIVERSIDADE FEDERAL DO PARANÁ | Revista Cadernos de Clio
Produção Nacional
Revisado por pares
Rafael Aparecido Carvalho Souza, Vito Labruna Cunha, Jonathan Henrique de Souza, Carlos Henrique Gomes Martins, Eduardo de Faria Franca, Marcos Pivatto, Javier Ellena, Leandro A. Faustino, Antonio Otávio T. Patrocínio, Victor M. Deflon, Pedro I. S. Maia, Carolina G. Oliveira,
In the present work, the synthesis, characterization, antifungal activity, molecular docking study and in silico approach of five thiosemicarbazone derivatives and their corresponding zinc(II) complexes are described. The compounds were characterized by elemental analysis, IR, UV-Vis and NMR spectroscopic measurements, molar conductivity measurements, emission spectra, high-resolution mass spectrometry and X ray study. The antifungal activity of the free ligands and synthesized compounds was preliminarily ...
Tópico(s): Organometallic Compounds Synthesis and Characterization
2022 - Elsevier BV | Journal of Inorganic Biochemistry
... Micbel de Montaigne. Os Índios brasileiros, do reino de Henrique II ao do Rei Sol, foram na França os únicos representantes do Novo Mundo; foram o ...
Tópico(s): History of Colonial Brazil
1993 - UNIVERSIDADE DE SÃO PAULO | Revista de História
Produção Nacional
... compreender as articulações entre gênero e poder na França Renascentista a partir da trajetória biográfica e política da rainha-mãe Catarina de Médici, esposa de Henrique II e regente de seu filho, o rei Carlos IX (1560-1574). Pretende-se analisar as particularidades do exercício do poder e da influência exercida por Catarina no contexto político das guerras de religião na França, primeiro como esposa, mas especialmente como viúva e ...
Tópico(s): Historical Gender and Feminism Studies
2021 - UNIVERSIDADE DE SÃO PAULO | Epígrafe
Produção Nacional
Revisado por pares
Patrícia S.V.B. de Almeida, Henrique Jefferson de Arruda, Gleyton Leonel Silva Sousa, Felipe Vitório Ribeiro, José Aleixo de Azevedo-França, Larissa A. Ferreira, Guilherme P. Guedes, Heveline Silva, Arthur Eugen Kümmerle, Amanda P. Neves,
Cationic Ru II complexes derived from coumarin hybrids and bipyridine have shown greater cytotoxicity than the free ligands. Our findings have been associated to the strongest ability of the complexes to interact with DNA.
Tópico(s): Synthesis and Characterization of Heterocyclic Compounds
2021 - Royal Society of Chemistry | Dalton Transactions
... Cardoso», [1957] 1985, p. 140. 51. J.-A. França, «Amadeo de Souza Cardoso», [1957] 1985, p. 140. 52. See particuarly Raquel Henriques da Silva, «Os anos do Orpheu e de Portugal Futurista», História da Arte Portuguesa, 1999, pp. 374–375; Bernardo Pinto de Almeida, Pintura Portuguesa do século XX, 2002, pp. 32–35; Maria Helena de Freitas, «Amadeo de Souza-Cardoso 1887–1918», Catálogo Raisonné Amadeo Souza Cardoso (Pintura – Vol. II), 2008, pp. 34–35; and João Pinharanda, «O ...
Tópico(s): History, Culture, and Society
2013 - Taylor & Francis | Konsthistorisk tidskrift/Journal of Art History
Produção Nacional
Lucas Gonçalves Santos, Marcos Paulo Valadares Silva, Raphael Dutra de Resende Mendonça, Isabelle Cristina Garcia Júlio, Henrique Campos Eto, Esdras de Campos França,
A compreensão e tratamento das más oclusões de Classe II representam um desafio substancial na ortodontia, exigindo análises minuciosas e estratégias terapêuticas personalizadas. A Classe II se caracteriza pela significativa discrepância anteroposterior entre as arcadas dentárias, podendo ser abordada em uma ou duas fases distintas. Este estudo teve como propósito revisar a literatura para comparar a eficácia dessas abordagens, enfatizando suas vantagens, desvantagens e efetividade. A revisão bibliográfica ...
Tópico(s): Dental Implant Techniques and Outcomes
2024 - Servicios Academicos Intercontinentales | Contribuciones a las Ciencias Sociales
Produção Nacional
Revisado por pares
Rafael Aparecido Carvalho Souza, Waleska R. P. Costa, Eduardo de Faria Franca, Meliza Arantes de Souza Bessa, Ralciane de Paula Menezes, Carlos Henrique Gomes Martins, Pedro I. S. Maia, Victor M. Deflon, Carolina G. Oliveira,
Tópico(s): Synthesis and Characterization of Heterocyclic Compounds
2021 - Elsevier BV | Journal of Inorganic Biochemistry
Produção Nacional
Franziska Schoeppe, Juçara Ribeiro Franca, Wilson Fandino, Adailson Siqueira, Alawiya Gadallah, Andrea Castillo Medina, Antoinette Oliveira Blackman, Ejaz Nadeem, Fabiana F. Gonçalves, Judith Sánchez-Raya, Hani Abdalla, J.I. Garrido González, Odimary Silva, Paula Kataguiri, Paulo Henrique Rosado-de-Castro, Regina Ruiz López, Sandro Pereira, Sol Calero, Lotfi B. Merabet,
Background and Aim: Diabetic macular edema (DME) is one of the leading causes of visual impairment among working-aged people responsible for more than 10,000 new cases of blindness per year. Although there are some therapeutical options for this disease, most of them are invasive, expensive, subject to a range of side effects, and may not be accessible to the entire population. In addition, conventional eye drops are not able to adequately deliver the drug to the posterior chamber of the eye, where ...
Tópico(s): Advanced Glycation End Products research
2017 - | Principles and Practice of Clinical Research Journal
... Habsburgos lutaram contra os reis franceses pela herança de Borgonha (1477-1493), a extensão dessas lutas à Itália, em que a França e a Espanha eram os verdadeiros adversários (1494-1516) e, acumulando os antagonismos antigos entre a Borgonha e a França, assim como entre a Espanha e a França, as cinco guerras entre Carlos V e Francisco I, inclusive os seus filhos herdeiros e sucessores Felipe II e Henrique II, pela hegemonia da Itália e do mundo ( ...
Tópico(s): Historical Education and Society
2003 - UNIVERSIDADE FEDERAL DO PARANÁ | História Questões & Debates
Produção Nacional
Revisado por pares
Diego Mariano, Carmelina Figueiredo Vieira Leite, Lucianna Helene Santos, Luís Fernando Marins, Karina Machado, Adriano Velasque Werhli, Leonardo Henrique França de Lima, Raquel C. de Melo-Minardi,
β-glucosidases are enzymes that catalyze the hydrolysis of oligosaccharides and disaccharides, such as cellobiose. These enzymes play a key role in cellulose degrading, such as alleviating product inhibition of cellulases. Consequently, they have been considered essential for the biofuel industry. However, the majority of the characterized β-glucosidases is inhibited by glucose. Hence, glucose-tolerant β-glucosidases have been targeted to improve the production of second-generation biofuels. In ...
Tópico(s): Enzyme Catalysis and Immobilization
2014 - Research Foundation of Ribeirão Preto | Genetics and Molecular Research
Produção Nacional
Revisado por pares
Leonice Dos Reis-Costa, Andreimar M. Soares, Suzelei de Castro França, Henrique C. Trevisan, Timothy K. Roberts,
Lipases are versatile enzymes regarding the range of reactions they catalyse and substrates on which they act. They are as well important as catalyst in organic synthesis. Their immobilization on appropriate supports confer them greater stability besides the possibility of operating in continuous reactors. In order to explore these abilities, the reactions involving hydrolysis of p-nitrophenyl acetate (PNPA) and transesterification of PNPA with n-butanol were chosen. Lipases from two different sources ...
Tópico(s): Pharmacological Effects and Assays
2003 - Bentham Science Publishers | Protein and Peptide Letters
Produção Nacional
Revisado por pares
Pedro Henrique França Gois, Daniele Canale, Weverton Machado Luchi, Rildo Aparecido Volpini, Mariana Matera Veras, Natália de Souza Xavier Costa, Maria Heloísa Massola Shimizu, Antônio Carlos Seguro,
Abstract Objectives To evaluate the occurrence of systemic and renal abnormalities in the offspring of Wistar rats exposed to tenofovir disoproxil fumarate (DF) during pregnancy. Methods Female Wistar rats received a standard diet, with or without addition of tenofovir DF (100 mg/kg diet), 1 week before mating and during pregnancy. Offspring from the tenofovir DF group were placed with an untreated foster mother during breastfeeding and compared with offspring from rats maintained on a standard diet ...
Tópico(s): Folate and B Vitamins Research
2014 - Oxford University Press | Journal of Antimicrobial Chemotherapy
Produção Nacional
Revisado por pares
Júlia Assunção de Castro Oliveira, Letícia Aline Fernandes, Karolina Gomes de Figueiredo, Eduardo José Azevedo Corrêa, Leonardo Henrique França de Lima, Dejane Santos Alves, Suzan Kelly Vilela Bertolucci, Geraldo Andrade Carvalho,
Spodoptera frugiperda control methods have proved to be inefficient, which justifies the search for new control measures. In this search for botanical insecticides for controlling S. frugiperda, the following were evaluated: (i) the toxicity of essential oils (EOs) from Cinnamodendron dinisii, Eugenia uniflora, and Melaleuca armillaris; (ii) the effect of EOs on life table parameters against S. frugiperda; (iii) the chemical characterization of EOs; and (iv) the in silico interaction of the chemical ...
Tópico(s): Insect-Plant Interactions and Control
2024 - Multidisciplinary Digital Publishing Institute | Plants
Produção Nacional
Revisado por pares
Thaís Ferreira Isabel, Guilherme Nunes Moreira Costa, Isabela B. Pacheco, Luana Gonçalves Barbosa, Célio Dias Santos Júnior, Fernando P.P. Fonseca, Johara Boldrini-França, Flávio Henrique‐Silva, Kelly Aparecida Geraldo Yoneyama, Renata Santos Rodrigues, Veridiana de Melo Rodrigues,
Snake venom serine proteases (SVSPs) are enzymes capable of interfering at several points of hemostasis. Some serine proteases present thrombin-like activity, which makes them targets for the development of therapeutics agents in the treatment of many hemostatic disorders. In this study, a recombinant thrombin-like serine protease, denominated rBpSP-II, was obtained from cDNA of the Bothrops pauloensis venom gland and was characterized enzymatically and biochemically. The enzyme rBpSP-II showed clotting ...
Tópico(s): Biochemical and Structural Characterization
2016 - Elsevier BV | Toxicon
Produção Nacional
Revisado por pares
Josencler L. Ribas Ferreira, María Noelia Lonné, Thiago A. França, Naiana Ribeiro Maximilla, Thiago Henrique Lugokenski, Patrícia Gomes Costa, Gilberto Fillmann, Félix Alexandre Antunes Soares, Fernando R. de la Torre, José María Monserrat,
Compounds from the nanotechnology industry, such as carbon-based nanomaterials, are strong candidates to contaminate aquatic environments because their production and disposal have exponentially grown in a few years. Previous evidence shows that fullerene C60, a carbon nanomaterial, can facilitate the intake of metals or PAHs both in vivo and in vitro, potentially amplifying the deleterious effects of these toxicants in organisms. The present work aimed to investigate the effects of fullerene C60 ...
Tópico(s): Nanoparticles: synthesis and applications
2013 - Elsevier BV | Aquatic Toxicology
Theodore C. Pierson, Barney S. Graham,
... De Oliveira W.T. do Carmo G.M. Henriques C.M. Coelho G.E. Araújo de França G.V. Increase in Reported Prevalence of Microcephaly ...
Tópico(s): Malaria Research and Control
2016 - Cell Press | Cell
Produção Nacional
Revisado por pares
Roberta de Oliveira Sousa Wanderley, Rossana Maria Feitosa de Figueirêdo, Alexandre José de Melo Queiroz, Francislaine Suélia dos Santos, Aline Priscila de França Silva, Yaroslávia Ferreira Paiva, Henrique Valentim Moura, Eugênia Telis de Vilela Silva, A. J. de B. Araújo, Marcos dos Santos Lima, Ana Regina Nascimento Campos, Mailson Gonçalves Gregório, Antônio Gilson Barbosa de Lima,
The aim of this study was to evaluate the effect of drying temperature on the quality of pomegranate peel (PPF) and seed (PSF) flours. The flours were obtained after drying the peel and seed at temperatures of 50, 60 and 70 °C until they reached hygroscopic equilibrium, were crushed and characterized in terms of phenolic compound profile, antioxidant activity and hygroscopic behaviour using water adsorption isotherms. Seventeen individual phenolic compounds were identified, quantified in PSF and 21 ...
Tópico(s): Nanocomposite Films for Food Packaging
2023 - Elsevier BV | LWT
Produção Nacional
Revisado por pares
Luiz Pinheiro, Carolina Nunes França, Maria Cristina de Oliveira Izar, Simone P. Barbosa, Henrique Tria Bianco, Soraia H. Kasmas, Gustavo Duarte Mendes, Rui Póvoa, Francisco Antônio Helfenstein Fonseca,
Significant decrease in outcomes with statins administration in the first 24 h of an acute myocardial infarction [1Spencer F.A. Fonarow G.C. Frederick P.D. Wright R.S. Every N. Goldberg R.J. et al.National Registry of Myocardial Infarction. Early withdrawal of statin therapy in patients with non-ST-segment elevation myocardial infarction: national registry of myocardial infarction.Arch Intern Med. 2004; 164: 2162-2168Crossref PubMed Scopus (113) Google Scholar, 2Fonarow G.C. Wright R.S. Spencer F. ...
Tópico(s): Acute Myocardial Infarction Research
2012 - Elsevier BV | International Journal of Cardiology
Produção Nacional
Revisado por pares
Norival A. Santos‐Filho, Johara Boldrini-França, Ludier Kesser Santos-Silva, Danilo L. Menaldo, Flávio Henrique‐Silva, Tiago Sampaio de Sousa, Adélia C.O. Cintra, Carla Cristine Neves Mamede, Fábio de Oliveira, Eliane Candiani Arantes, Lusânia Maria Greggi Antunes, Eduardo Maffud Cilli, Suely Vilela Sampaio,
Venomous and non-venomous snakes possess phospholipase A2 (PLA2) inhibitory proteins (PLIs) in their blood serum. This study shows the expression and biochemical and functional characterization of a recombinant alpha inhibitor from Bothrops alternatus snake, named rBaltMIP. Its expression was performed in Pichia pastoris heterologous system, resulting in an active recombinant protein. The expressed inhibitor was tested regarding its ability to inhibit the phospholipase activity of different PLA2s, ...
Tópico(s): Marine Invertebrate Physiology and Ecology
2014 - Elsevier BV | Biochimie
Produção Nacional
Revisado por pares
Luciana Souza de Aragão-França, Viviane C. J. Rocha, André Cronemberger Andrade, Fábio Henrique Brasil da Costa, Juliana Fraga Vasconcelos, Daniel Abensur Athanazio, Daniela Nascimento Silva, Everaldo Silvino dos Santos, Cássio Santana Meira, Cintia Figueiredo de Araújo, Jéssica Vieira Cerqueira, Fabı́ola Cardillo, Neuza Maria Alcântara‐Neves, Milena Botelho Pereira Soares, Lain Carlos Pontes-de-Carvalho,
The use of tolerogenic dendritic cells (TolDCs) to control exacerbated immune responses may be a prophylactic and therapeutic option for application in autoimmune and allergic conditions. The objective of this work was to evaluate the effects of TolDC administration in a mouse model of allergic airway inflammation caused by mite extract.Mouse bone marrow-derived TolDCs were induced by incubation with granulocyte-macrophage colony-stimulating factor (GM-CSF) and dexamethasone, and then characterized ...
Tópico(s): Immunotherapy and Immune Responses
2018 - | Allergy Asthma and Immunology Research
Produção Nacional
Revisado por pares
Lucas Borges Ferreira, Fernando França da Cunha, Gustavo Henrique da Silva, Flávio Bastos Campos, Santos Henrique Brant Dias, JANNAYTON E.O. SANTOS,
The Penman-Monteith equation is recommended for the estimation of reference evapotranspiration (ETo). However, it requires meteorological data that are commonly unavailable. Thus, this study evaluates artificial neural network (ANN), multivariate adaptive regression splines (MARS), and the original and calibrated Hargreaves-Samani (HS) and Penman-Monteith temperature (PMT) equations for the estimation of daily ETo using temperature. Two scenarios were considered: (i) local, models were calibrated/developed ...
Tópico(s): Hydrological Forecasting Using AI
2021 - Brazilian Academy of Sciences | Anais da Academia Brasileira de Ciências
Produção Nacional
Revisado por pares
Ludmila Barbosa de Souza Balsimelli, Jamille Costa de Oliveira, Flora Ávila Adorno, Clarissa A. Brites, Giuliano Stefanello Bublitz, Lara Cristina de Carvalho Tavares, Karina Munhoz de Paula Alves Coelho, Jaqueline Stall, Paulo Henrique Condeixa de França,
<b><i>Objective:</i></b> Intraoperative examination is a highly valuable tool for the evaluation of central nervous system (CNS) lesions, helping the neurosurgeon to determine the best surgical management. This study aimed to evaluate the accuracy and to analyze the diagnostic disagreements and pitfalls of the intraoperative examinations through correlation with the final histopathological diagnosis in CNS lesions. <b><i>Study Design:</i></b> Retrospective ...
Tópico(s): Brain Metastases and Treatment
2019 - Karger Publishers | Acta Cytologica
Produção Nacional
Revisado por pares
Rafael E. O. Rocha, Diego Mariano, Tiago Silva Almeida, Leon Sulfierry CorrêaCosta, Pedro Fischer, Lucianna Helene Santos, Ernesto R. Caffarena, Carlos Henrique da Silveira, Leonida M. Lamp, Monica L. Fernández‐Quintero, Klaus R. Liedl, Raquel C. de Melo-Minardi, Leonardo Henrique França de Lima,
Abstract β‐glucosidases play a pivotal role in second‐generation biofuel (2G‐biofuel) production. For this application, thermostable enzymes are essential due to the denaturing conditions on the bioreactors. Random amino acid substitutions have originated new thermostable β‐glucosidases, but without a clear understanding of their molecular mechanisms. Here, we probe by different molecular dynamics simulation approaches with distinct force fields and submitting the results to various computational ...
Tópico(s): Enzyme Structure and Function
2022 - Wiley | Proteins Structure Function and Bioinformatics
Produção Nacional
Revisado por pares
João Henrique Lopes, Carla Giometti França, Marisa Masumi Beppu,
The ternary membrane-forming system based on the silk fibroin (SF), glycerol (GLY) and sol-gel precursor of 58S bioactive glass (BG) was studied for the preparation of novel and multifunctional hybrid membranes. The morphology of membranes was observed by scanning electron microscopy (SEM) and spectral imaging, by X-ray mapping technique, were performed in order to investigate the chemical homogeneity of elements. The results show that there is a critical limit for the concentration of GLY and BG for ...
Tópico(s): Collagen: Extraction and Characterization
2019 - Elsevier BV | European Polymer Journal
Produção Nacional
Revisado por pares
Terry Ruas, Charles Henrique Porto Ferreira, William I. Grosky, Fabrício Olivetti de França, Débora Maria Rossi de Medeiros,
The relationship between words in a sentence often tells us more about the underlying semantic content of a document than its actual words, individually. In this work, we propose two novel algorithms, called Flexible Lexical Chain II and Fixed Lexical Chain II. These algorithms combine the semantic relations derived from lexical chains, prior knowledge from lexical databases, and the robustness of the distributional hypothesis in word embeddings as building blocks forming a single system. In short, ...
Tópico(s): Text and Document Classification Technologies
2020 - Elsevier BV | Information Sciences
Produção Nacional
Revisado por pares
Clarissa A. Brites, Ludmila B. S. Balsimelli, Karina M. P. A. Coelho, Hercílio Fronza-Júnior, Jaqueline Stall, Paulo Henrique Condeixa de França,
Introduction:The thyroid cytopathologic classification based on The Bethesda System for Reporting Thyroid Cytopathology (TBSRTC) standardized results derived from fine-needle aspiration (FNA).It has facilitated communication among clinicians, seems to reduce the number of unnecessary thyroidectomies and also improves the quality of malignancy detection.Objective: To evaluate the correlation between cytopathological samples classified according to TBSRTC and their histological finding after specimen ...
Tópico(s): Thyroid Cancer Diagnosis and Treatment
2018 - Sociedade Brasileira de Patologia Clínica | Jornal Brasileiro de Patologia e Medicina Laboratorial