Produção Nacional
Revisado por pares
Talita da Silva Mendes de Farias, Ariclécio Cunha de Oliveira, Sandra Andreotti, Fernanda Gaspar do Amaral, Patrícia Chimin, André Ricardo Alves de Proença, Francisco Leonardo Torres‐Leal, Rogério Antônio Laurato Sertié, Amanda Baron Campaña, Andressa Bolsoni Lopes, Arnaldo Henrique de Souza, José Cipolla‐Neto, Fábio Bessa Lima,
Melatonin, the main hormone produced by the pineal gland, is secreted in a circadian manner (24-hr period), and its oscillation influences several circadian biological rhythms, such as the regulation of clock genes expression (chronobiotic effect) and the modulation of several endocrine functions in peripheral tissues. Assuming that the circadian synchronization of clock genes can play a role in the regulation of energy metabolism and it is influenced by melatonin, our study was designed to assess ...
Tópico(s): Neurobiology and Insect Physiology Research
2015 - Wiley | Journal of Pineal Research
Produção Nacional
Revisado por pares
Rodrigo D. Requião, Henrique José Araujo de Souza, Silvana Rossetto, Tatiana Domitrovic, Fernando L. Palhano,
It has been proposed that polybasic peptides cause slower movement of ribosomes through an electrostatic interaction with the highly negative ribosome exit tunnel. Ribosome profiling data-the sequencing of short ribosome-bound fragments of mRNA-is a powerful tool for the analysis of mRNA translation. Using the yeast Saccharomyces cerevisiae as a model, we showed that reduced translation efficiency associated with polybasic protein sequences could be inferred from ribosome profiling. However, an ...
Tópico(s): Viral Infections and Immunology Research
2016 - Taylor & Francis | RNA Biology
Produção Nacional
Revisado por pares
Rodrigo D. Requião, Luiza Fernandes, Henrique José Araujo de Souza, Silvana Rossetto, Tatiana Domitrovic, Fernando L. Palhano,
As proteins are synthesized, the nascent polypeptide must pass through a negatively charged exit tunnel. During this stage, positively charged stretches can interact with the ribosome walls and slow the translation. Therefore, charged polypeptides may be important factors that affect protein expression. To determine the frequency and distribution of positively and negatively charged stretches in different proteomes, the net charge was calculated for every 30 consecutive amino acid residues, which ...
Tópico(s): Protein Structure and Dynamics
2017 - Public Library of Science | PLoS Computational Biology
Produção Nacional
Revisado por pares
Tiago Henrique de Souza, José Antonio Hersan Nadal, Roberto José Negrão Nogueira, Ricardo Pereira, Marcelo Barciela Brandão,
The coronavirus disease 2019 (COVID-19) outbreak is an unprecedented global public health challenge, leading to thousands of deaths every day worldwide. Despite the epidemiological importance, clinical patterns of children with COVID-19 remain unclear. The aim of this study was to describe the clinical, laboratorial, and radiological characteristics of children with COVID-19.The Medline database was searched between December 1st 2019 and April 6th 2020. No language restrictions were applied. Inclusion ...
Tópico(s): Kawasaki Disease and Coronary Complications
2020 - Wiley | Pediatric Pulmonology
Produção Nacional
Revisado por pares
Tiago Henrique de Souza, José Antonio Hersan Nadal, Andressa Oliveira Peixoto, Ricardo Pereira, Marina Pavan Giatti, Ana Carolina Siqueira Soub, Marcelo Barciela Brandão,
Tópico(s): Atomic and Subatomic Physics Research
2019 - Springer Science+Business Media | European Journal of Pediatrics
Produção Nacional
Revisado por pares
Lívia Noronha Coelho-de-Souza, José Henrique Leal‐Cardoso, Francisco José de Abreu Matos, Saad Lahlou, Pedro Jorge Caldas Magalhães,
The effects of the essential oil of Eucalyptus tereticornis Sm. (EOET) on guinea-pig tracheal smooth muscle were investigated. EOET (10 - 1000 μg/mL) relaxed the tracheal basal tonus with an EC50 value of 125.3 [52.2 - 300.9] μg/mL. Its maximal relaxation (40 ± 6 %) was significantly lower than that evoked by aminophylline (209 ± 34 %). The K+-(60 mM)-induced contractions were significantly reduced by both EOET (200 - 1000 μg/mL) and its main constituent 1,8-cineole (600 - 1000 μg/mL). Acetylcholine (1 μM)-induced contractions ...
Tópico(s): Traditional Chinese Medicine Analysis
2005 - Thieme Medical Publishers (Germany) | Planta Medica
Produção Nacional
Revisado por pares
Daniel José Silva Oliveira, Paulo Henrique de Souza Bermejo, José Roberto Pereira, Daniely Aparecida Barbosa,
Resumo A análise de sentimento é uma técnica de descoberta de conhecimento por meio da mineração de dados, sua finalidade é revelar a opinião das pessoas sobre temas específicos. Essa é uma técnica apropriada para aplicação em fontes de dados não estruturados, como as mídias sociais, que abarcam informações sobre diversos temas, inclusive política e administração pública. O objetivo deste estudo foi identificar se a análise de sentimento pode refletir a opinião pública e, assim, trazer contribuições ...
Tópico(s): Internet Traffic Analysis and Secure E-voting
2019 - FUNDAÇÃO GETÚLIO VARGAS | Revista de Administração Pública
Produção Nacional
Revisado por pares
Michel Henriques de Souza, José Domingos Pereira Júnior, Skarlet De Marco Steckling, Jussara Mencalha, Fabíola dos Santos Dias, João Romero do Amaral Santos de Carvalho Rocha, Pedro Crescêncio Souza Carneiro, José Eustáquio de Souza Carneiro,
The evaluation of cultivars using multi-environment trials (MET) is an important step in plant breeding programs. One of the objectives of these evaluations is to understand the genotype by environment interaction (GEI). A method of determining the effect of GEI on the performance of cultivars is based on studies of adaptability and stability. Initial studies were based on linear regression; however, these methodologies have limitations, mainly in trials with genetic or statistical unbalanced, heterogeneity ...
Tópico(s): Plant pathogens and resistance mechanisms
2020 - Public Library of Science | PLoS ONE
Produção Nacional
Revisado por pares
Gustavo da Silveira, Fernando Irajá Félix de Carvalho, Antônio Costa de Oliveira, Igor Pirez Valério, Giovani Benin, Guilherme Ribeiro, Maraisa Crestani Hawerroth, Henrique de Souza Luche, José Antônio Gonzalez da Silva,
Os objetivos do trabalho foram determinar a adaptabilidade e estabilidade do rendimento de grãos de dez genótipos de trigo (Triticum aestivum L.), contrastantes para o caráter potencial de afilhamento, implantados em diferentes densidades de semeadura. Os experimentos foram realizados nas safras agrícolas de 2005, 2006 e 2007, no município de Capão do Leão (RS) e na safra de 2007 nos municípios de Pato Branco (PR) e Ijuí (RS) Utilizou-se o delineamento de parcelas divididas, com a parcela composta pelo ...
Tópico(s): Soil Management and Crop Yield
2010 - INSTITUTO AGRONÔMICO DE CAMPINAS | Bragantia
Produção Nacional
Revisado por pares
Maraisa Crestani Hawerroth, Solange Ferreira da Silveira Silveira, Elisane Weber Tessmann, Itamara Mezzalira, Henrique de Souza Luche, José Antonio Gonzalez da Silva, Luiz Carlos Gutkoski, Fernando Irajá Félix de Carvalho, Antônio Costa de Oliveira,
Tópico(s): Genetics and Plant Breeding
2012 - Springer Science+Business Media | Euphytica
Produção Nacional
Revisado por pares
Nildo Antônio Arruda de Abreu, Vander Mendonça, Breno Gonçalves Ferreira, Glauco Antônio Teixeira, Henrique Antunes de Souza, José Darlan Ramos,
Conduziu-se este experimento com o objetivo de avaliar o crescimento de mudas tipo pé-franco de pitangueira em diferentes substratos com utilização de superfosfato simples conduzidos em um viveiro de formação de mudas localizado no Campus da Universidade Federal de Lavras (UFLA), Minas Gerais. Foram estudadas quatro doses de superfosfato simples 0; 2,5; 5 e 10 kg m-3 de substrato e duas misturas de substratos: A (composto orgânico + areia + solo, na proporção de 1:1:3 em volume) e B (Plantmax® + areia + solo, ...
Tópico(s): Pineapple and bromelain studies
2005 - UNIVERSIDADE FEDERAL DE LAVRAS | Ciência e Agrotecnologia
Produção Nacional
Revisado por pares
Henrique de Souza Luche, José Antônio Gonzalez da Silva, Luciano Carlos da Maia, Antônio Costa de Oliveira,
Looking at the new demands of the global agricultural scenario, the search for more productive, efficient and stress adapted genotypes has attracted attention of plant breeders regarding plants with improved physiological characteristics. Therefore, the stay-green trait has taken proeminence as an important strategy to overcome the current yield plateaus allied with yield adaptability and stability. This review has aimed to bring light the main aspects of the stay-green character, showing their ...
Tópico(s): Plant Genetic and Mutation Studies
2015 - UNIVERSIDADE FEDERAL DE SANTA MARIA | Ciência Rural
Produção Nacional
Revisado por pares
Edson Lopes da Ponte, Paloma Leão Sousa, Maria Valdenir A.P. Rocha, Pedro Marcos Gomes Soares, Andrelina Noronha Coelho‐de‐Souza, José Henrique Leal‐Cardoso, Ana Maria Sampaio Assreuy,
Tópico(s): Essential Oils and Antimicrobial Activity
2012 - Elsevier BV | Pharmacological Reports
Produção Nacional
Revisado por pares
Alisson Barbosa de Souza, Paulo A. L. Rêgo, Vinay Chamola, Tiago Carneiro, Paulo Henrique Gonçalves Rocha, José Neuman de Souza,
Complex vehicular applications, such as automatic driving and augmented reality are delay sensitive and require massive computational resources. Despite being more connected and smarter, vehicles still cannot appropriately meet the demands of these applications. By allowing neighboring vehicles and edge servers coupled to base stations to share their available computing resources, vehicular edge computing systems help to handle these applications. Then, vehicles can use the task offloading technique ...
Tópico(s): Transportation and Mobility Innovations
2023 - Institute of Electrical and Electronics Engineers | IEEE Systems Journal
Produção Nacional
Revisado por pares
Nayara Mussi Monteze, Breno Bernardes‐Souza, Henrique José de Paula Alves, Fernando Luiz Pereira de Oliveira, José M. Oliveira, Sílvia Nascimento de Freitas, Raimundo Marques do Nascimento Neto, Maria Lilian Sales, Gabriela Guerra Leal Souza,
In order to investigate the response of heart rate variability (HRV) components to postural change and their association with cardiovascular risk factors in shift workers, a cross-sectional study with 438 Brazilian males rotating shift workers was done. Anthropometric, body composition, and clinical measures were collected. Electrocardiogram was recorded for 3 minutes, in the supine and orthostatic position, and HRV components were extracted. Descriptive analyses showed that mean values of body mass ...
Tópico(s): Non-Invasive Vital Sign Monitoring
2015 - Hindawi Publishing Corporation | BioMed Research International
Produção Nacional
Revisado por pares
José Borges-Pereira, José Adail Fonseca de Castro, José Henrique Furtado Campos, José de Souza Nogueira, Patrícia Lago Zauza, Patrícia Marques, Maria Angélica Cardoso, Constança Britto, Adauto Araújo,
In order to investigate aspects of the infection and morbidity of Chagas' disease in the municipality of João Costa, Piauí State, Brazil, we carried out a serological survey to detect anti-Trypanosoma cruzi antibodies in 2,080 individuals, by indirect immunofluorescence, indirect hemagglutination and ELISA. A total of 189 seropositive and 141 seronegative patients were evaluated by anamnesis, physical exam and electrocardiogram (EKG). The parasitaemia of 106 chagasic patients was evaluated by indirect ...
Tópico(s): Parasites and Host Interactions
2002 - Brazilian Society of Tropical Medicine | Revista da Sociedade Brasileira de Medicina Tropical
Produção Nacional
Revisado por pares
Marcellus Henrique Loiola Ponte de Souza, José Maurício Mota, R. B. Oliveira, Fernando Q. Cunha,
Tópico(s): Helicobacter pylori-related gastroenterology studies
2008 - Springer Science+Business Media | Inflammation Research
Produção Nacional
Revisado por pares
Jacilane Ximenes Mesquita, Tarcísio Vieira de Brito, Thais Pontes Carvalho Fontenelle, Renan O. Silva, Marcellus Henrique Loiola Ponte de Souza, José Luiz de Souza Lopes, Leila Maria Beltramini, André Luiz dos Reis Barbosa, Ana Lúcia Ponte Freitas,
Tópico(s): Phytochemical compounds biological activities
2020 - Elsevier BV | International Journal of Biological Macromolecules
Produção Nacional
Revisado por pares
Dieniffer Peixoto‐Neves, Kerly Shamyra da Silva‐Alves, Maria Diana Moreira Gomes, Felipe Crescêncio Lima, Saad Lahlou, Pedro Jorge Caldas Magalhães, Vânia Marilande Ceccatto, Andrelina Noronha Coelho‐de‐Souza, José Henrique Leal‐Cardoso,
Abstract Various essential oils are rich in carvacrol, a monoterpenic phenol isomeric with thymol. This study was undertaken to assess the vasorelaxant effects of thymol and carvacrol in rat isolated aorta and the putative mechanisms underlying these effects. Thymol and carvacrol produced a concentration‐dependent relaxation on the aortic ring preparations pre‐contracted using KCl (IC 50 value of 64.40 ± 4.41 and 78.80 ± 11.91 μ m , respectively) or using phenylephrine (PHE, 0.1 μ m ) (IC 50 value of 106.40 ± ...
Tópico(s): Phytochemistry and Biological Activities
2009 - Wiley | Fundamental and Clinical Pharmacology
Produção Nacional
Revisado por pares
Pergentino José C. Sousa, Cybelle Façanha Barreto Medeiros Linard, D. Azevedo-Batista, Ariclécio Cunha de Oliveira, Andrelina Noronha Coelho‐de‐Souza, José Henrique Leal‐Cardoso,
Mentha x villosa Huds (Labiatae) is an aromatic herb widely used in folk medicine. Since the essential oil of the herb has many pharmacological activities, including antispasmodic effects, we determined whether the oil and its major constituent, piperitenone oxide (PO), have antinociceptive activity. The essential oil of M. x villosa (EOMV) and PO administered orally at 200 mg/kg (vehicle: 0.1% Tween 80 in water) significantly reduced the writhings induced by acetic acid from control values of 59.5 ± ...
Tópico(s): Olfactory and Sensory Function Studies
2009 - Associação Brasileira de Divulgação Científica | Brazilian Journal of Medical and Biological Research
Produção Nacional
Revisado por pares
Rebeca Peres Moreno Maia-Joca, Humberto C. Joca, Francisca Jéssica Penha Ribeiro, Renata Vieira do Nascimento, Kerly Shamyra da Silva‐Alves, Jáder Santos Cruz, Andrelina Noronha Coelho‐de‐Souza, José Henrique Leal‐Cardoso,
This study investigated the mechanisms underlying the vascular effects of terpinen-4-ol in isolated rat aortic ring preparations.The thoracic aortae of healthy rats were submitted to isometric tension recording. Membrane resting potential and input membrane resistance were measured by conventional microelectrode technique.Terpinen-4-ol reversibly relaxed endothelium-containing preparations pre-contracted with high K(+) and phenylephrine with IC50 values of 421.43 μM and 802.50 μM, respectively. ...
Tópico(s): Electrochemical Analysis and Applications
2014 - Elsevier BV | Life Sciences
Produção Nacional
Revisado por pares
R. T. H. Fogaça, A. D. A. Cavalcante, A. K. L. Serpa, Pergentino José C. Sousa, Andrelina Noronha Coelho‐de‐Souza, José Henrique Leal‐Cardoso,
The effects of the essential oil of Mentha x villosa (EOMV) was investigated in saponin-permeabilized fibres and in intact sartorius muscle of the toad. In intact muscle EOMV at concentrations from 1 to 100 μg/mL blocked the contraction induced by high (80 mM) potassium and induced potentiation of caffeine-induced muscle contraction. From 1 to 6 mg/mL EOMV elicited contraction in both depolarized (by 110 mM K+) and non-depolarized (4 mM K+) muscle fibres. This contraction was blocked by procaine. At ...
Tópico(s): Muscle activation and electromyography studies
1997 - Wiley | Phytotherapy Research
Produção Nacional
Revisado por pares
Alisson Silva Souza, André Márcio de Lima Curvello, Flávio Luís dos Santos de Souza, Henrique José da Silva,
Based on the E-noe 6 project, this paper developed with the purpose to reduce damages and losses caused by flood in urban centers, through the cheap flood warning system to authorities and population. The system monitors the water level of a runway or river and according to the risk with the level, triggers emergency alerts to the authorities through telephone calls and SMS messages. For the population, there are light beacons that define the situation of the river. The data is collected in cloud ...
Tópico(s): Water Quality Monitoring Technologies
2017 - Elsevier BV | Procedia Computer Science
Produção Nacional
Revisado por pares
Ana Carolina Cardoso-Teixeira, Francisco Walber Ferreira‐da‐Silva, Dieniffer Peixoto‐Neves, Klausen Oliveira-Abreu, Átila Pereira-Gonçalves, Andrelina Noronha Coelho‐de‐Souza, José Henrique Leal‐Cardoso,
The present study used isometric tension recording to investigate the vasorelaxant effect of limonene (LM), carveol (CV), and perillyl alcohol (POH) on contractility parameters of the rat aorta, focusing in particular on the structure-activity relationship. LM, CV, and POH showed a reversible inhibitory effect on the contraction induced by electromechanical and pharmacomechanical coupling. In the case of LM, but not CV and POH, this effect was influenced by preservation of the endothelium. POH and ...
Tópico(s): Eicosanoids and Hypertension Pharmacology
2018 - Multidisciplinary Digital Publishing Institute | Molecules
Produção Nacional
Revisado por pares
Kesley A.O. Pontes, Leandro S. Silva, Edgleyson C. Santos, Alessandro S. Pinheiro, Douglas E. Teixeira, Diogo B. Peruchetti, Rodrigo P. Silva‐Aguiar, Camila Wendt, Kildare Miranda, Andrelina Noronha Coelho‐de‐Souza, José Henrique Leal‐Cardoso, Celso Caruso‐Neves, Ana Acácia S. Pinheiro,
Malaria is a parasitic disease that compromises the human host. Currently, control of the Plasmodium falciparum burden is centered on artemisinin-based combination therapies. However, decreased sensitivity to artemisinin and derivatives has been reported, therefore it is important to identify new therapeutic strategies. We used human erythrocytes infected with P. falciparum and experimental cerebral malaria (ECM) animal model to assess the potential antimalarial effect of eugenol, a component of ...
Tópico(s): Mosquito-borne diseases and control
2020 - Elsevier BV | Biochimica et Biophysica Acta (BBA) - General Subjects
Produção Nacional
Revisado por pares
Crystianne Calado Lima, Camille Maria de Holanda-Angelin-Alves, Átila Pereira-Gonçalves, Emanuel Kennedy-Feitosa, Eder Evangelista-Costa, Maria Amélia Carneiro Bezerra, Andrelina Noronha Coelho‐de‐Souza, José Henrique Leal‐Cardoso,
Croton zehntneri is a plant well adapted to the semi-arid climate of northeastern region of Brazil. The essential oil of C. zehntneri (EOCz) has been described to have several pharmacologic properties, including effect on airflow resistance of in vivo respiratory system. For this reason, we investigated the hypothesis that EOCz and its major constituents, anethole and estragole, have antispasmodic activity on tracheal muscle. In tracheal rings of Wistar rats, maintained in Krebs-Henseleit's solution, ...
Tópico(s): Insect Pheromone Research and Control
2020 - Elsevier BV | Heliyon
Produção Nacional
Revisado por pares
Kerly Shamyra da Silva‐Alves, Francisco Walber Ferreira‐da‐Silva, Dieniffer Peixoto‐Neves, Kátia Virginia Viana-Cardoso, Luiz Moreira‐Júnior, Morgana Barroso Oquendo, Klausen Oliveira-Abreu, A.A.C. Albuquerque, Andrelina Noronha Coelho‐de‐Souza, José Henrique Leal‐Cardoso,
Estragole is a volatile terpenoid, which occurs naturally as a constituent of the essential oils of many plants. It has several pharmacological and biological activities. The objective of the present study was to investigate the mechanism of action of estragole on neuronal excitability. Intact and dissociated dorsal root ganglion neurons of rats were used to record action potential and Na+ currents with intracellular and patch-clamp techniques, respectively. Estragole blocked the generation of action ...
Tópico(s): Plant-based Medicinal Research
2013 - Associação Brasileira de Divulgação Científica | Brazilian Journal of Medical and Biological Research
Produção Nacional
Revisado por pares
Francisco Walber Ferreira‐da‐Silva, Kerly Shamyra da Silva‐Alves, Thaís Antônia Alves-Fernandes, Andrelina Noronha Coelho‐de‐Souza, José Henrique Leal‐Cardoso,
1,8-Cineole is a terpenoid present in many essential oil of plants with several pharmacological and biological effects, including antinociceptive, smooth muscle relaxant and ion channel activation. Also, 1,8-cineole blocked action potentials, reducing excitability of peripheral neurons. The objective of this work was to investigate effects of 1,8-cineole on Na+ currents (INa+) in dissociated superior cervical ganglion neurons (SCG). Wistar rats of both sexes were used (10–12 weeks old, 200–300 g). ...
Tópico(s): Olfactory and Sensory Function Studies
2015 - Elsevier BV | Neuroscience Letters
Produção Nacional
Revisado por pares
Átila Pereira-Gonçalves, Francisco Walber Ferreira‐da‐Silva, Camille Maria de Holanda-Angelin-Alves, Ana Carolina Cardoso-Teixeira, Andrelina Noronha Coelho‐de‐Souza, José Henrique Leal‐Cardoso,
Tópico(s): Ion Channels and Receptors
2018 - Springer Science+Business Media | Pflügers Archiv - European Journal of Physiology
Produção Nacional
Revisado por pares
Marcelo Sacardi Bíudes, George L. Vourlitis, Maísa Caldas Souza Velasque, Nadja Gomes Machado, Victor Hugo de Morais Danelichen, Vagner Marques Pavão, Paulo Henrique Zanella de Arruda, José de Souza Nogueira,
Gross primary production (GPP) is the total amount of fixed carbon and depends on vegetation health and water and energy availability. GPP has been monitored worldwide by flux towers and models that are coupled with remotely sensed data, such as by Moderate Resolution Imaging Spectroradiometer (MODIS). However, models have not been evaluated for tropical savanna, which presumably represent a challenge because of large spatial and seasonal variation in GPP. Thus, our goal was to evaluate the Vegetation ...
Tópico(s): Land Use and Ecosystem Services
2021 - Elsevier BV | Agricultural and Forest Meteorology