Barry Anscombe, Dan Lyle, Waldemar Januszczak, Banca del Gottardo, Trevor Cousins, David Mills, Sally Brock, Professor Gideon Garter, Amanda Ursell, Giles Newton, Jonathan Miller, Gareth Walsh, Ferdinand Mount, Sam Gilpin, Neil Wormald, David James Smith, Richard Simpson, Martin James, David O'Connell, Rosie Millard, David Hewson, Hugh Canning, James Turner, Andrew Stone, Peter Kemp, Hilary Clarke, David Marriott, Charlie Finn, Alistair McGowan, Danny Wallace, John Humphrys, Nicholas Hellen, Brown, Christopher Morgan, Mark Ludlow, Alicia Wyllie, Bernice Foreman, Toru Kurihara, Gitangeli Sapra, David Campese, Uzi Mahnaimi, Michael Wright, Michael Arditti, Chris Harris, Nick Rennison, Olivier Magne, Gareth Southgate, John Elliott, Sarah Allan, Mireille Hess, Laurence Phillips, Richard Brooks Arts Editor, Adrian Moorhouse, Brendan Simms, Godfrey Smith, Clare Rewcastle, Michael Powell, Matthew Campbell, David Hutcheon, Mary Braid, Liam Clarke, Graham Norwood, David Budworth, William Lewis Business editor, Rev Marcus Braybrooke, Ian Leeming, Susannah Price, Sarah Baxter, Victoria Stanley, Dan Pearson, Jason Dawe, Alfred Uluinayau, Sian Griffiths, Jonathan Northcroft, Hala Jaber, Matthew Wall, Graham Martin-Royle, N J, Francois Pienaar, Felice Hardy, Peter Whittle, Andrew Longmore, Lesley White, Jo Whiley, Jonny Wilkinson, E P, Peter Woodcock, Andrew Sullivan, Clive Davis, Woke Afeani, Tom Otley, Nick Miller, Barry McCanna, Nick Speed, Cally Law, David Bond, Alasdair Reid, Victoria Segal, Edward Porter, Anthony Peregrine, Eben Black, Dave Pollard, Pam Barren, Adam Nathan, Shelley von Strunckel, Michael Preston, Sir Sigmund Sternberg, Paul Donovan, Zoe Thomas, Steve Boyd, Hugh McIlvanney, Julie Earle-Levine, Sylvia Davies, Stuart Andrews, David Leppard, Joss Bolton, Michael Sweeney, Peter Whirtle, Cheddar Man, Gareth Huw Davies, David Cracknell, Katrina Manson, Diana Wright, Robbie Burns, Peter Koenig, Natalie Graham, David Scott, Jessica Brinton, David Walsh, Sarah Keenlyside, Stephen Armstrong, Boby Trolley, Mark Anstead, Bethan Cole, Ray Hutton, … Zedginidze, A A Gill, Andrew Shaw, Matt Phillips, Keith Phillips, Lorraine Hadley, Nigel Powell, Brian Doogan, Ben Dowell, Jonathan Futrell, Hugh Pearman, Maia Dunphy, Richard Lewis, Helen Stewart, Jason Robinson, John Dugdale, Barbara Hall, Nigel Botherway, Jon Swain, Rob Hughes, John Peter, Phil Read, Donna Leon, Josh Lewsey, David Smith, Gerry Bucke, Tim Richards, Patton Howell, David Cracknell Political Editor, J M Coetzee, Dean Richards, Mary Sheridan, Dipesh Gadher Transport Correspondent, Bryan Redpath, Lawrence Dallaglio, Nicholas Hellen Social Affairs Editor, John Eilliott, Peter Watson, Stewart Lee, Peter Conradi, Helen Kenny, Patricia Nicol, John O'Donnell, Sir Richard Branson, Jeremy Guscott, Hannah Sealey, Sir John Walsh, Khaled Abu Toameh, Joe Van Niekerk, Vincent Crump, Jilly Cooper, Chris Woodhead, Alen Glanville, Brendan Russell, Mark Nickless, Keith Pattison, Alex Clark, Phil Keith-Roach, Mark Edwards, Rachel Bridge, Susan Clark, Stuart Miles, Jonathan Carr-Brown Health Correspondent, Sean Newsom, Sheikh Dr. M Zaki Badawi, Raymond Keene, Dick Best, C Williams, Stephen Jones, Louise Armitstead, Nick Cain, Frankel, Trevor Lewis, Andrew Sanger, Collin McDowell's, Roland White, Sarah Hughes, Peter Hardy, Richard Rae, Mark Franchetti, Jon Ungoed-Thomas, Michael Sheridan, Barry Collins, Rani Singh, John Waples, Ros Dodd, Lois Wilson, Stephen Pettitt, Maria McErlane, Jonathan Calvert, Will Ramsay, Justin Sparks, Joe Lovejoy, Dan Cairns, David Smith Economics Editor, Helen Vandevelde, Chris Feetenby, Kevin Beeston's, Bill McLaren, Simon Howard, Dominic Rushe, Dr Philip Bramley, Karen Robinson, Marilyn Woozley, Robin Cook, Scott Athorne, Alpay Ozalan, Trevor Leota, Helen Davies, Frank Whitford, Jack Lynes, Kathryn Cooper, William Lewis, P D, Andy Woodman, Humphrey Carpenter, Lynne Truss, Andrew Porter, Tony Allen-Mills, Simon Wilde, Robert Winnett, John Rogers, Irwin Stelzer, Robert Hewison, Peter Wilson, Mark Maguire, David Dougill, Gloria Edwards, Rob Maul, Nigel Melville, Jeremy Clarkson, David Cairns, Philip Smith, Dean Nelson, Peter Upton, Bob Walker, Norman Hoffman, Joy Wolfe, Kate Stone, Jason Leonard, Greg Struthers, Karena Batstone, Paula Robinson, Roger Eglin, Dominique Coughlin, Lucinda Kemeny, Jasper Gerard, Derek Clements, Paul Driver, Wstin Pichot, Ian Hawkey, Paul Durman, Lisa Grainger, Arnie Wilson, Lisa Armstrong, Sean Edwards, Alex Codling, Mick Dennis, David Beckham, Denise Van Outen, Christina Lamb, Victoria O'Brien, Rod Liddle, Cosmo Landesman, Sean O'Flynn, Dominic O'Connell, Lesley Young, Rachel Causier, Caroline Donald, Rustam Kaliyev, Colin McDowell, Joe Colombo, Judith O'Reilly, Ashley Potter, James Simpson Daniel, Simon Bell, John Harlow, Lesley Knight, Martin Brasher, James Foxall, Martin Wroe, Byron Kelleher, Malcolm O'kelly, Lewis Stuart, Claudia Croft, Will Iredale, Jonathan Leake Science Editor, Sally Kinnes, Naomi Caine, David Wickers, Minette Marrin, Andrew Davidson, Paul Stephen Lubicz, David Robertson, Matthew Goodman, India Knight, Stephen Tumim, Kingston Smith, Paul,
... Britney Spears or Justin From Japanese games masters Hideo Kojima and Yoji We've been going on about ...
2003 - Gale Group | Sunday Times HA GDA
... rearing literature from the Tokugawa period on by Kojima Hideo reveals a persistent emphasis on providing the before ... New York: W. H. Freeman & Co., 1986). 34. Kojima Hideo, Childrearing Concepts as a Belief-Value System of ...
Tópico(s): Japanese History and Culture
1989 - Cambridge University Press | Journal of Japanese Studies
Neil J. Salkind, Hideo Kojima, Tamar Zelniker,
SALKIND, NEIL J.; KOJIMA, HIDEO; and ZELNIKER, TAMAR. Cognitive Tempo in American, Japanese, and Israeli Children. CHILD DEVELOPMENT, 1978, 49, 1024-1027. Data on ...
Tópico(s): Cognitive Abilities and Testing
1978 - Wiley | Child Development
... film Battles without Honor or Humanity (1973), and Kojima Hideo's videogame Metal Gear Solid (1998). Fukasaku's opening sequence employs photographic stills of the mushroom cloud, burnt-out ruins, and the black market to set the violence of yakuza gangs against the political-military violence of the United States. A generation later, Kojima's game used photographic stills of the atomic ...
Tópico(s): Multimedia Communication and Technology
2019 - Taylor & Francis | Japanese Studies
G. Kojima, Hideo Kojima, Y. Tabata,
Abstract (1) A process to produce C2F4-C3H6 copolymer of molecular weight over 150 000 was established by exploiting a new catalyst which permits low temperature polymerization. (2) A vulcanization recipe, comprised of peroxide and TAIC, was established to give the copolymer superior vulcanizate properties. (3) Polymer structure and properties were elucidated, and the high potential as a heat-resistant elastomer was shown. (4) The resultant vulcanizate has been proved to be a unique fluoroelastomer ...
Tópico(s): Polymer Nanocomposites and Properties
1977 - American Chemical Society | Rubber Chemistry and Technology
Hajime Takayama, Nobukata Shinohara, Akemi Koyanagi, Yoshiko Someya, Satoko Hanaoka, Hidefumi Kojima, Hideo Yagita, Ko Okumura, Yoichi Shinkai,
... Oxford Academic PubMed Google Scholar Hidefumi Kojima, Hidefumi Kojima Search for other works by this author on: Oxford Academic PubMed Google Scholar Hideo Yagita, Hideo Yagita 1Department of Immunology, Juntendo University ...
Tópico(s): CAR-T cell therapy research
1991 - Oxford University Press | International Immunology
Masataka Kuwana, Y. Kurata, K Fujimura, K Fujisawa, Hideo Wada, Toshiro Nagasawa, Shosaku� Nomura, Tetsuhito Kojima, Hideo Yagi, Y. Ikeda,
We proposed diagnostic criteria for immune thrombocytopenic purpura (ITP) by modifying the existing guidelines for diagnosis of ITP and by incorporating laboratory tests found useful for predicting its diagnosis, for example erythrocyte count, leukocyte count, anti-GPIIb/IIIa antibody-producing B cells, platelet-associated anti-GPIIb/IIIa antibodies, percentage of reticulated platelets, and plasma thrombopoietin.To validate our criteria, we conducted a multi-center prospective study involving 112 ...
Tópico(s): Autoimmune Bullous Skin Diseases
2006 - Elsevier BV | Journal of Thrombosis and Haemostasis
Forced vibrations of a simply supported beam having an attached non-linear dynamic vibration absorber and excited by sinusoidal motion of its supporting base are investigated analytically. The absorber produces a hardening spring force in the form of a cubic curve. The governing partial differential equation reduces to the well-known Duffing equation, which is solved by the harmonic balance method. Besides the simple harmonic motion solution, the third order superharmonic and one-third order subharmonic ...
Tópico(s): Mechanical Engineering and Vibrations Research
1983 - Elsevier BV | Journal of Sound and Vibration
Keiko Kita, Nobutsugu Hiraoka, Fusao Kimizuka, Akira Ôbayashi, Hiroyuki Kojima, Hideo Takahashi, Hiuga Saito,
The kinetic constants of the site-specific endonuclease, ScaI, for various substrates were determined. We estimated Vmax and Km for octa-, deca-, dodeca-, and hexadecanucleotides and for plasmid pBR322 DNA. Vmax for these substrates were close, but Km were quite different (in decreasing order, octa- greater than deca-, dodeca-, hexadeca- greater than pBR322). The results were discussed with respect to the tertiary structure of substrate.
Tópico(s): RNA and protein synthesis mechanisms
1985 - Oxford University Press | Nucleic Acids Research
Hisashi Kojima, Hideo Tominaga, Shigeki Sato, Haruo Ogura,
Three new pentacyclic triterpenes together with several known triterpenes have been isolated as their methyl esters from the roots of Prunella vulgaris.
Tópico(s): Plant Toxicity and Pharmacological Properties
1987 - Elsevier BV | Phytochemistry
Hisashi Kojima, Hideo Tominaga, Shigeki Sato, Hiroaki Takayanagi, Haruo Ogura,
Abstract Two new hexacyclic triterpenoids, isolated as their methyl esters from the roots of Prunella vulgaris , were established by spectroscopic evidence and chemical correlation to be (12 R ,13 S )-2α,3α,24-trihydroxy-12,13-cyclotaraxer-14-en-28-oic acid and (13 S ,14 R )-2α,3α,24-trihydroxy-13,14-cyclo-olean-11-en-28-oic acid.
Tópico(s): Plant biochemistry and biosynthesis
1988 - Elsevier BV | Phytochemistry
Akira Hashimoto, Hiroshi Yamaguchi, Takayoshi Suzuki, Kazuo Kashiwabara, Masaaki Kojima, Hideo D. Takagi,
Abstract Nickel(II) complexes containing P–N‐type bidentate hybrid ligands of 2‐aminoethylphosphanes (RR′Pea; RR′ = Ph 2 or MePh) or 8‐quinolylphosphanes (RR′Pqn), namely [Ni(P–N) 2 ](BF 4 ) 2 [P–N = Ph 2 Pea ( 1 ), MePhPea ( 2 ), Ph 2 Pqn ( 3 ), or MePhPqn ( 4 )] have been prepared, and their structural, spectroscopic, and electrochemical properties determined. The crystal structure analysis indicates that the 2‐aminoethylphosphane complexes ( 1 and 2 ) have a square‐planar coordination geometry around the Ni II center with a cis ( ...
Tópico(s): Magnetism in coordination complexes
2009 - Wiley | European Journal of Inorganic Chemistry
Osamu Okazaki, Chieko Kojima, Hideo Hakusui, M Nakashima,
The enantioselective disposition of ofloxacin (OFLX) was studied in healthy subjects after oral administration of (+/-)-OFLX at a dose of 200 mg. S-(-)-OFLX and R-(+)-OFLX concentrations in serum and urine were measured separately by high-performance liquid chromatography, and various pharmacokinetic parameters were calculated from the data. The ratio of S-(-) to R-(+) enantiomer concentrations in serum showed a increase with time, with S/R ratios of 1.01 at 2 h and 1.31 at 24 h. The terminal elimination ...
Tópico(s): Cancer therapeutics and mechanisms
1991 - American Society for Microbiology | Antimicrobial Agents and Chemotherapy
Taiji Furukawa, Fumio Konishi, Kazuhisa Shitoh, Masayuki Kojima, Hideo Nagai, Toshihiko Tsukamoto,
Abstract BACKGROUND The Amsterdam criteria are used worldwide for the clinical diagnosis of hereditary nonpolyposis colorectal carcinoma (HNPCC). In Japan, clinical criteria (JCC) have been proposed to identify as many HNPCC cases as possible, but the suitability of the JCC remains uncertain. In this article, the authors evaluate retrospectively whether the JCC are adequate to diagnose HNPCC compared with the Bethesda guidelines (BG) and also investigated useful screening methods for HNPCC. METHODS ...
Tópico(s): Digestive system and related health
2002 - Wiley | Cancer
Taichi Matsumoto, Yasushi Takayama, Noriyuki Wada, Hiroaki Onoda, Kazuo Kojima, Hideo Yamada, Hajimu Wakabayashi,
Poly-organo-siloxane spherical particles were synthesized by a sol–gel method from methyltrimethoxysilane (MTMS) using a W/O emulsion comprising of sorbitantrioleate (SPAN85), n-octane, and H2O. MTMS was hydrolyzed and condensed without acid and/or basic catalysts in this W/O emulsion at room temperature. The size of the spherical silica particle depends on both the composition of the emulsion and the reaction time, ranging from 1 to 80 µm in diameter. A W/O emulsion comprising 10 wt% SPAN85, 60 wt% ...
Tópico(s): Polyoxometalates: Synthesis and Applications
2003 - Royal Society of Chemistry | Journal of Materials Chemistry
Tomonari Akamatsu, Yoshimi Hatakeyama, Takahito Kojima, Hideo Soeda,
A bstract The rate of occurrence of click trains of two harbor porpoises ( Phocoena phocoena ) were counted during 14 nights. We developed an echolocation signal detection system that was harnessed to a porpoise and activated a light when the animal emitted an echolocation signal. This device, referred to as a click‐light, detects echolocation signals above 150 dB re 1 μPa in the 28–180 kHz range. Echolocation rates, i.e., occurrences of click trains, changed frequently, ranging from 0 to 25 per minute. ...
Tópico(s): Bat Biology and Ecology Studies
1994 - Wiley | Marine Mammal Science
Yoichi Maekawa, Yoshiaki Minato, Chieko Ishifune, Takeshi Kurihara, Akiko Kitamura, Hidefumi Kojima, Hideo Yagita∥, Mamiko Sakata‐Yanagimoto, Takashi Saito, Ichiro Taniuchi, Shigeru Chiba, Saburo Sone, Koji Yasutomo,
Tópico(s): Cancer-related molecular mechanisms research
2008 - Nature Portfolio | Nature Immunology
Rui Gan, Yumiko Yamanaka, Takaaki Kojima, Hideo Nakano,
Abstract We developed a method for coupling protein to its coding DNA on magnetic microbeads using emulsion PCR and cell‐free protein synthesis in emulsion. A PCR mixture containing streptavidin‐coated microbeads was compartmentalized by water‐in‐oil (w/o) emulsion with estimated 0.5 template molecules per droplet. The template molecules were amplified and immobilized on beads via bead‐linked reverse primers and biotinylated forward primers. After amplification, the templates were sequentially labeled ...
Tópico(s): Bacteriophages and microbial interactions
2008 - American Chemical Society | Biotechnology Progress
Keishi Makino, Ryota Kojima, Hideo Nakamura, Motohiro Morioka, Ken-ichi Iyama, Kazuto Shigematsu, Jun‐ichi Kuratsu,
Ectopic adrenal cortical neoplasms are extremely rare; few involve the central nervous system (CNS). We report a 17-month-old girl with spinal adrenal cortical neoplasms. She was unable to crawl or stand and was irritable at night. Her appearance was asymmetrical; the right side of her face and her lower right leg were enlarged. In addition, she manifested hyperplasia of the thymus, fibrous hyperplasia of the bladder, and hamartoma in the liver. However, all abnormalities were asymptomatic. Magnetic ...
Tópico(s): Glioma Diagnosis and Treatment
2010 - Springer Science+Business Media | Brain Tumor Pathology
Nariaki Inoue, Hiromi Watanabe, Shigeaki Kojima, Hideo Sekiguchi,
Tópico(s): Parasite Biology and Host Interactions
2007 - Springer Science+Business Media | Fisheries Science
Takayoshi Suzuki, Hiroshi Yamaguchi, Akira Hashimoto, Koichi Nozaki, Mototsugu Doi, Naoya Inazumi, Noriaki Ikeda, Satoshi Kawata, Masaaki Kojima, Hideo D. Takagi,
The tetrafluoroborate salt of bis{8-(diphenylphosphino)quinoline}copper(I), [Cu(Ph(2)Pqn)(2)]BF(4), afforded orange prismatic (2O) or yellow columnar (2Y) crystals, dependent on the solvent and concentration of the recrystallization solution used. X-ray analysis revealed that crystals of 2O and 2Y had the same composition and exhibited different crystal systems: 2O was triclinic, with space group P ̅1 and Z = 2, and 2Y was monoclinic with space group P2(1)/c and Z = 4. In these crystals, the tetrahedral ...
Tópico(s): Crystallography and molecular interactions
2011 - American Chemical Society | Inorganic Chemistry
Hisanaga Horie, Masaki Okada, Masayuki Kojima, Hideo Nagai,
Tópico(s): Colorectal Cancer Surgical Treatments
2006 - Springer Science+Business Media | Surgery Today
Ryosuke Kojima, Hideo Takakura, Takeaki Ozawa, Yukio Tada, Tetsuo Nagano, Yasuteru Urano,
Shine on: A new rational design strategy for near-infrared-emitting firefly luciferins that are available in vivo has been developed using intramolecular bioluminescence resonance energy transfer (BRET). The emission wavelength could be freely tuned by the choice of BRET acceptor, and NIR bioluminescence could be detected in living cells and mice without the need for luciferase manipulation. Bioluminescence, especially that of the firefly, is widely used as an analytical tool in the life sciences, ...
Tópico(s): Cell Image Analysis Techniques
2012 - Wiley | Angewandte Chemie International Edition
Ikuho Kojima, Hideo Mogami, Hiroshi Shibata, Etsuro Ogata,
We previously reported that insulin-like growth factor-I (IGF-I) stimulated calcium entry (Kojima, I., Matsunaga, H., Kurokawa, K., Ogata, E., and Nishimoto, I. (1988) J. Biol. Chem. 263, 16561-16567) and production of 1,2-diacylglycerol in IGF-responsive Balb/c 3T3 cells (Kojima, I., Kitaoka, M., and Ogata, E. (1990) J. Biol. Chem. 265, 16846-16850). The present study was conducted to determine a role of protein kinase C (PKC) in the progression activity of IGF-I. To monitor the activity of PKC in intact ...
Tópico(s): Growth Hormone and Insulin-like Growth Factors
1993 - Elsevier BV | Journal of Biological Chemistry
Itaru Kojima, Hideo Mogami, Norio Kawamura, Horoshi Yasuda, Hiroshi Shibata,
Activin A is a homodimerie protein structurally related to transforming growth factor-β. The present study was conducted to examine the effect of activin A on the growth of rat vascular smooth muscle cells (VSMC) in culture. When serum-deprived cells were incubated with activin A, nuclear labeling of bromodeoxy-uridine occurred after a 12-h lag period. The effect of activin A on nuclear labeling was dose-dependent, being maximal at 10-9M. Activin A also increased the number of VSMC after 30 h of ...
Tópico(s): Growth Hormone and Insulin-like Growth Factors
1993 - Elsevier BV | Experimental Cell Research
Hiroyuki Kawahigashi, Sakiko Hirose, Kenjirou Ozawa, Yoshiko Ido, Misaki Kojima, Hideo Ohkawa, Yasunobu Ohkawa,
Tópico(s): Plant tissue culture and regeneration
2005 - Springer Science+Business Media | Transgenic Research
Kenichi Kumasaka, Takashi Kojima, Hideo Honda, Kayo Doi,
Screening and quantitative analysis for six sulfonylurea-type oral antidiabetic agents (SU-OADs), tolbutamide (TOL), acetohexamide (ACE), chlorpropamide (CHL), gliclazide (GLC), glibenclamide (GLB), and glimepiride (GLM), in adulterated health food has been developed. The SU-OADs were extracted with acetone and then the extract was subjected to thin-layer chromatography (TLC) and high-performance liquid chromatography (HPLC). In the TLC analysis, good separation was achieved with a mixture of n-butyl acetate ...
Tópico(s): Pharmacy and Medical Practices
2005 - Pharmaceutical Society of Japan | JOURNAL OF HEALTH SCIENCE
Akihiko Ishijima, H Kojima, Hideo Higuchi, Yoshie Harada, Takashi Funatsu, Toshio Yanagida,
Tópico(s): Neuroscience and Neural Engineering
1996 - Elsevier BV | Biophysical Journal
Lei Gao, Keisuke Kojima, Hideo Nagashima,
Hyperbranched polystyrene bearing ammonium salts (HPS-NR3+Cl−) behaves as an excellent stabilizer of ruthenium, rhodium, iridium, palladium, and platinum nanoparticles from 1 to 3 nm in size uniformly dispersed in the polymer matrix. The catalytic performance of the resulting metal-polymer composites, M@HPS-NR3+Cl−, is dependent on the metal. This dependence was investigated by assessing the hydrogenation of alkenes and arenes. The utility of M@HPS-NR3+Cl− as reusable catalysts in aqueous/organic ...
Tópico(s): Gold and Silver Nanoparticles Synthesis and Applications
2015 - Elsevier BV | Tetrahedron
Ryosuke Kojima, Hideo Takakura, Mako Kamiya, Eiji Kobayashi, Toru Komatsu, Tasuku Ueno, Takuya Terai, Kenjiro Hanaoka, Tetsuo Nagano, Yasuteru Urano,
Abstract A sensitive bioluminogenic probe for highly reactive oxygen species (hROS), SO 3 H‐APL, was developed based on the concept of dual control of bioluminescence emission by means of bioluminescent enzyme‐induced electron transfer (BioLeT) and modulation of cell‐membrane permeability. This probe enables non‐invasive visualization of physiologically relevant amounts of hROS generated deep inside the body of living rats for the first time. It is expected to serve as a practical analytical tool ...
Tópico(s): Electrochemical sensors and biosensors
2015 - Wiley | Angewandte Chemie