Richard Flectcher, Jonathan Northcroft, David Wood, John Dugdale, Paul Theroux, Barbara Hall, Gemma Levine, Jim Munro, Sally Brock, Jack C Smith, Rob Hughes, Jason Dawe, John Peter, V S, Professor Gideon Garter, John Waples Business Editor, Susan d'Arcy, Frank Whitford, Nicolette Jones, Matt Wolf, Kathryn Cooper, Peter Salter, David Smith, David Cracknell Political Editor, Vivienne Westwood, Andrew Sullivan, Clive Davis, John Bramall, Craig Newcombe, Flora Bagenal, Brian Lewis, Denise Boutall, Damlan Barr, Simon Wilde, Robert Sandall, Robert Winnett, Micheal Smith, Irwin Stelzer, Peter Wilson, Rosie Millard, David Dougill, Christopher Hart, Alison Thomson, Lois Roger, Stuart Barnes, Jason Allardyce, Paul Flynn, Anne Enright, Jamie Rickers, Joe Habbab, Hugh Canning, Jeremy Clarkson, Victoria Segal, Edward Porter, David Cairns, Stewart Lee, Claire Newell, Michael Portillo, Bob Walker, Alan Harpley, Sarah Dempster, Greg Gordon, Dave Pollard, Richard Fletcher, Greg Struthers, Lydia Slater, Jeremy Guscott, Graham Keeley, Paul Ham, Christopher Silvester, Paul Donovan, Ali Rifat, Jeremy Clark, Giles Hattersley, Paul Kimmage, Chris Woodhead, Steve Boyd, Jasper Gerard, Aggie MacKenzie, Paul Driver, Alan Brown John, William Holland, Richard Brooks, Caroline Scott, Shelley Von Strunckel, Christopher Morgan, David Leppard, Paul Durman, Bridget Freer, Joan Woodhall, Mark Edwards, Judith le Fleming, Heston Blumenthal, Stephen Amidon, Flora Begenal, P Kemp, Patrick Stewart, Phil Baker, Hugo Barnacle, John Chamberlin, Catherine Baudrand, Lois Rogers, Sean Newsom, Raymond Keene, Joanna Lumley, Rod Liddle, Dominic Lutyens, David Cracknell, Robbie Hudson, Cosmo Landesman, Rod Dreher, Gavin Conway, Benji Wilson, B R J Simpson, Peter Koenig, Louise Armitstead, Uzi Mahnaimi, Nazi Justice, Nick Cain, Stephen Bleach, Lucy Atkins, Natalie Graham, John Cardosi, Tim Moorey, Nick Rennison, Jeremy Lewis, Rob Ryan, Miranda Seymour, David Walsh, Ian Critchley, Helen Brown, Ivo Tonnant, John Martin, De Carter, Trevor Lewis, Bryan Appleyard, Colin McDowell, Stephen Armstrong, John Elliott, Ron Clarke, Michael Palin's, Mark Anstead, Gary Bibby, Michael Sheridan Far East Correspondent, Dave Pearce, R W Johnson, Kate Suiter, Roland White, Steven Swinford, Paul Duffy, Shane Watson, Waldemar Januszozak, Abul Taher, Maurice Chittenden, Richard Brooks Arts Editor, Joby Williams, Linda Burrows, Richard Rae, Mark Franchetti, Jon Ungoed-Thomas, Lucy Ewing, M E, Clare Francis, Desmond Dekker, Michael Smith, Barry Collins, Chris Haslam, Peter Johns, Mark Kleinman, John Waples, Paul Rowan, A A Gill, Kara O'Reilly, Peter O'Reilly, Brian Glanville, Simon Jenkins, Stephen Pettitt, Claudia Croft, Will Iredale, Jonathan Calvert, Jessica Bown, R H, Rajiv Radhakrishnan, Sally Kinnes, Sean O'brien, Peter Almond, Brian Doogan, Michael Clower, Simon Buckland, Minette Marrin, John Aizlewood, Clifford Bishop, Robert Service, Simon Kurs, Graham Norwood, Andrew Frankel, Joe Lovejoy, Jonathan Futrell, David Budworth, Andrew Davidson, Dan Cairns, Pete Oliver, Mrs Mills, David Smith Economics Editor, Penny Perrick, Sarah Baxter, Brian Schofield, Carey Scott, Kate Spicer, Matthew Goodman, India Knight, Jonothan Northcroft, Barry Newcombe, Dominic Rushe, Richard Lewis, Karen Robinson, Helen Stewart,
... football fans. I … Bolton's enigmatic Japanese midfielder Hidetoshi Nakata stands apart from his fellow players both on ...
2006 - Gale Group | Sunday Times HA GDA
H. Hatori, Yasuhiro Yamada, Minoru Shiraishi, Hidetoshi Nakata, Suehiko Yoshitomi,
Tópico(s): Silicone and Siloxane Chemistry
1992 - Elsevier BV | Carbon
Jonathan James-Moore, Michael Prescott, Steve Pittard, Margaret James, Matthew Wall, Mo Shapiro, Don Taylor, C Thibaut, John Follain, Barbara Hall, Frank Parker, Daniela Paudice, J B, Christine McGourty, Francois Pienaar, Fred Redwood, Carole Dawson, Aady Knott, Jon Swain, John Perter, James Clark, Nicholas Rufford, John Peter, Pam Barrett, Jan Ladbrooke, Amanda Ursell, Emma Moore, Lorraine Harvey, Miranda Innes, Lance Jenkins, John Jay, J D, Sally Thomson, Frank Whitford, Ivo Tennant, Martin Butler, M Bibal, Sam Gilpin, Sally O'Reilly, Tanya, David Smith, Graham Henry, Richard Bond, caroline Donald, Melanie Phillips, Nick Pitt, Neil Wormald, E P, Andrew Sullivan, Dave Ferris, Clive Davis, Preston King, Mary Wilson, Sarah Keighley, Hywel Williams, Ella, Clive Woodward, William Brittain, Tony Allen-Mills, Martin James, Isabella Blow, John Gardner, Tom Walker, Anthony Sattin, Robert Winnett, Nick Gardber, Irwin Stelzer, Charles Nicholl, Tom English, Robert Hewison, Peter Wilson, Roger Anderson, Simon Fanshawe, Lawrence Dallaglio, David Dougill, York Membery, John Mortimer, John Evans, Philip Kingsley, Cathy Cooper, Sue Clayton, David Hewson, J Alexander, Tania Alexander, Cath Sylvester, Cary L Cooper, Margaret Coles, Hugh Canning, Alasdair Reid, Hugh Mcllvanney, Margarette Driscoll, Martin Davies, Jeremy Clarkson, Peter Watson, Nigel Williams, Dorothy Andrew, Christine Stopp, Louise Taylor, John Waples Deputy City Editor, Edward Porter, Max Anderson, Stewart Lee, Peter Kemp, K E Mawardy, Eben Black, Nick Newman's, Brian Rowe, Lynne Wallis, Graham, Tony Misiolek, Phil Craigie, Adam Nathan, James Bailey, Phil Greening, Nick Gardner, Robert Howlett, Phillip Oppenheim, Stuart Wavell, Stella Bingham, Josephine Smit, Alastair Hendy, Neil Back, Sir Richard Sykes, Clive Jacobs, Lisa Jardine, Simon Mills, Cosmo Landerson, James Clark Home Affairs Correspondent, Smita Talati, Paul Driver, Paul Bray, Malcolm Farrow, Gillian Taylforth, John Humphrys, Andrew Hagley, Maeve Sheehan, Nicholas Hellen, Peter Windsor, Richard Brooks, Ian Hawkey, David Thomas, Steve, Christopher Morgan, Rob Lane editor, Shelley Von Strunckel, Tim Rayment, Brian Jackman, Geoffrey Holmes, Antonella Lazzeri, Sue Beenstock, Mark Edwards, Duncan Lawson, Sarah Gracie, Susan Clark, Ken Livingstone, Mark Austin, David Lawrenson, Eben Black Chief Political Correspondent, Liz Reld, Matt Dawson, Rose, Danny O'Brien, T W, Jennifer Asiama, Alan Combes, Sue Reid, Raymond Keene, Senay Boztas, Zoe Brennan, Cosmo Landesman, Diana Wright, Kipper Williams, S N, David Orr, Chris Partridge, Stephen Jones, Richard Evans, Peta Bee, Melanie Philips, Arnaud Bani, Bill Turque, M J, Gary Buchanan, Rob Ryan, Dr John Greensmith, Claire Oldfield, David Walsh, Trevor Lewis, Jack Grimston, S P, Bryan Appleyard, Lois Rogers Medical Correspondent, Colin McDowell, Stephen Armstrong, F C, Ron Clarke, Christopher Goodwin, Josh Salzmann, Bethan Cole, Mark Prigg, Victoria O'brien, Roland White, Garth Alexander, Robert Henderson, Kim Fletcher, David Young, Maurice Chittenden, Alex Fortune, Kevin Pratt, Richard Brooks Arts Editor, Richard Rae, Mark Franchetti, Jonathan Powell, Ray Hutton, Jon Ungoed-Thomas, Andrew Oakes, Andrew Rogers, Michele Kirsch, Deborah Williams, Jonathan Leake, S J, John Crossland, Michael Sheridan, Christine Webb, Alison Steed, Godfrey Smith, Wendy Worviell, Jacqueline Champ, Camp Beaumont, Hilary Lowe, Trevor Rees-Jones, John Waples, Jeremy Hart, Hunter Davies, A A Gill, Anna Selby, Matthew Campbell, Brian Glanville, Anthony Croft, Tom Robbins, Stephen Pettitt, Jonathan Leake Science Editor, Karen MacGregor, Jeremy Langmead, R H, Eric McGraw, Andrew Lorenz, Sally Kinnes, Naomi Caine, Hazel Courteney, Nicholas Hellen Media Editor, David Wickers, Silvia Rodgers, Roger Dobson, Tom Rhodes, John Chambers, Len Tyler, John Aizlewood, Mrs J Hughes, Emma Penn, Mark Hodson, Graham Norwood, Joe Lovejoy, Jonathan Futrell, Mark Porter, Rupert Steiner, David Parstey, Dan Cairns, David Grylls, David Parsley, Allan Hall, Thomas Gilchrist, Brian Alexis, Claire Burston, David Smith Economics Editor, Ken Ellis, Mrs D Brooker, Simon Crerar, Anthony Howard, Helen Vandevelde, Martin Booth, Bob Dwyer, Walter Ellis, Joanna Simon, India Knight, Stephen Peters, Steve Grant, Simon Howard, Danny Danziger, Dan Pearson, Lisa Verrico, Dominic Rushe, Boris Schapiro, Karen Robinson,
... son shines Roma's clever £16m signing of Hidetoshi Nakata opens up a huge commercial market Chelsea must ...
2000 - Gale Group | Sunday Times HA GDA
H. Hatori, Yasuhiro Yamada, Minoru Shiraishi, Hidetoshi Nakata, Suehiko Yoshitomi,
Tópico(s): Silicone and Siloxane Chemistry
1992 - Elsevier BV | Carbon
Hidekazu Koike, Haruki Nakazato, Nobuaki Ohtake, Hiroshi Matsui, Hironobu Okugi, Yasuhiro Shibata, Seiji Nakata, Hidetoshi Yamanaka, Kazuhiro Suzuki,
Tópico(s): Pharmacogenetics and Drug Metabolism
2008 - Springer Science+Business Media | International Urology and Nephrology
Tatsuya Okubo, Shinobu Nakata, Hidetoshi Nagamoto, Manabu Ihara, Hiroshi Komiyama,
The grain density of chemical vapor deposition (CVD) diamond film is greatly enhanced via controlled surface pretreatment in hexane medium under ultrasonic irradiation. Surface treatment of the substrate prior to the deposition is essential for continuous diamond film formation by CVD processing. Generally the pretreatment is carried out using diamond powder dispersed in alcohol or acetone medium under ultrasonic irradiation. In this study we used hexane as a dispersion medium, and synthesized diamond ...
Tópico(s): Semiconductor materials and devices
1993 - Institute of Physics | Japanese Journal of Applied Physics
Hiroshi Matsui, Kazuhiro Suzuki, Nobuaki Ohtake, Seiji Nakata, Toshiyuki Takeuchi, Ituro Inoue, Hidetoshi Yamanaka,
... Population Hiroshi Matsui, Kazuhiro Suzuki, Nobuaki Ohtake, Seiji Nakata, Toshiyuki Takeuchi, Ituro Inoue, and Hidetoshi Yamanaka Hiroshi MatsuiHiroshi Matsui , Kazuhiro SuzukiKazuhiro Suzuki , Nobuaki OhtakeNobuaki Ohtake , Seiji NakataSeiji Nakata , Toshiyuki TakeuchiToshiyuki Takeuchi , Ituro InoueIturo Inoue , and Hidetoshi YamanakaHidetoshi Yamanaka View All Author Informationhttps://doi.org/ ... Nobuaki Ohtake More articles by this author Seiji Nakata More articles by this author Toshiyuki Takeuchi More articles by this author Ituro Inoue More articles by this author Hidetoshi Yamanaka More articles by this author Expand All ...
Tópico(s): Prostate Cancer Treatment and Research
2004 - Lippincott Williams & Wilkins | The Journal of Urology
Tomoya Uchimura, Toshifumi Asano, Takao Nakata, Akitsu Hotta, Hidetoshi Sakurai,
Duchenne muscular dystrophy (DMD) is a muscle degenerating disease caused by dystrophin deficiency, for which therapeutic options are limited. To facilitate drug development, it is desirable to develop in vitro disease models that enable the evaluation of DMD declines in contractile performance. Here, we show MYOD1-induced differentiation of hiPSCs into functional skeletal myotubes in vitro with collagen gel and electrical field stimulation (EFS). Long-term EFS training (0.5 Hz, 20 V, 2 ms, continuous ...
Tópico(s): Tissue Engineering and Regenerative Medicine
2021 - Elsevier BV | Cell Reports Medicine
Kenya Nakata, Tatsuya Tokumaru, Hidetoshi Iwamoto, Yutaka Nishigaichi, Isamu Shiina,
Seventh heaven: The enantiodivergent synthesis of (+)- and (−)-centrolobines was achieved in a total of seven steps by using an asymmetric esterification in the presence of catalytic (R)-(+)-N-methylbenzoguanidine as the key reaction.
Tópico(s): Axial and Atropisomeric Chirality Synthesis
2013 - Wiley | Asian Journal of Organic Chemistry
Lilong Zhou, D Liu, Kazuya Nakata, Takuya Tsumura, Hidetoshi Fujii, Kenji Ikeuchi, Y. Michishita, Yasuyuki Fujiya, M. Morimoto,
A new technique of self-refilling friction stir welding (SRFSW) relying on non-consumable joining tool has been developed to repair the keyhole left at the end of 316L stainless steel friction stir welding/friction stir processing (FSW/FSP) seam. The conventional FSW process was transformed by adopting a series of non-consumable tools with gradual change in geometry to create a solid state refilled joint step by step. Using the combined plastic deformation and flow of the material around the keyhole, ...
Tópico(s): Aluminum Alloy Microstructure Properties
2012 - Maney Publishing | Science and Technology of Welding & Joining
Kazuhiro Suzuki, Haruki Nakazato, Hiroshi Matsui, Hidekazu Koike, Hironobu Okugi, Bunzo Kashiwagi, Masahiro Nishii, Nobuaki Ohtake, Seiji Nakata, Kazuto Ito, Hidetoshi Yamanaka,
Abstract BACKGROUND Estrogen is one of the crucial hormones participating in the proliferation and carcinogenesis of the prostate glands. Genetic polymorphisms in the estrogen metabolism pathway might be involved in the risk of prostate carcinoma development. The authors evaluated the association between genetic polymorphisms in estrogen‐related enzymes and receptors and the risk of developing familial prostate carcinoma. METHODS In the current study, 101 cases with prostate carcinoma whose first‐ ...
Tópico(s): Glutathione Transferases and Polymorphisms
2003 - Wiley | Cancer
Hiroshi Matsui, Kazuhiro Suzuki, Nobuaki Ohtake, Seiji Nakata, Toshiyuki Takeuchi, Hidetoshi Yamanaka, Ituro Inoue,
Prostate cancer (PC) is one of the most common causes of cancer mortality in Western countries, and familial aggregation of PC is well known. Multiple PC susceptibility loci have been reported in Western countries, but attempts to confirm the loci in independent data sets have proven to be inconsistent. We performed a genomewide linkage analysis with 53 affected sib pairs to identify genetic loci related to PC in a Japanese population. Two linkage analyses, GENEHUNTER-PLUS and SIBPAL, were applied ...
Tópico(s): Genetic Associations and Epidemiology
2003 - Springer Nature | Journal of Human Genetics
Masamitsu Konno, Hideshi Ishii, Jun Koseki, Nobuhiro Tanuma, Naohiro Nishida, Koichi Kawamoto, Tatsunori Nishimura, Asuka Nakata, Hidetoshi Matsui, Kozou Noguchi, Miyuki Ozaki, Yuko Noguchi, Hiroshi Shima, Noriko Gotoh, Hiroaki Nagano, Yuichiro� Doki, Masaki Mori,
The M2 isoform of pyruvate kinase, the final rate-limiting enzyme of aerobic glycolysis, is expressed during embryonic development. In contrast, the M1 isoform is expressed in differentiated cells due to alternative splicing. Here we investigated murine embryonic stem cells (ESCs) with Pkm1 or Pkm2 knock-in alleles. Pkm1 allele knock-in resulted in excessive oxidative phosphorylation and induced the formation of cysteine-thiol disulfide-dependent complexes of forkhead box class-O (FOXO) transcription ...
Tópico(s): Pancreatic function and diabetes
2015 - Elsevier BV | Regenerative Therapy
Li Zhou, Kazuya Nakata, Takuya Tsumura, Hidetoshi Fujii, Kenji Ikeuchi, Y. Michishita, Yasuyuki Fujiya, M. Morimoto,
Tópico(s): Aluminum Alloy Microstructure Properties
2014 - Springer Science+Business Media | Journal of Materials Engineering and Performance
Kazuya Nakata, Y.G. Kim, Hidetoshi Fujii, Takuya Tsumura, T. Komazaki,
Tópico(s): Aluminum Alloy Microstructure Properties
2006 - Elsevier BV | Materials Science and Engineering A
Daniel Makori Menge, Emi Kameoka, Mana Kano‐Nakata, Akira Yamauchi, Shuichi Asanuma, Hidetoshi Asai, Mayumi Kikuta, Roel Rodriguez Suralta, Takuya Koyama, Thiem Thi Tran, J. Siopongco, Shiro Mitsuya, Yoshiaki Inukai, Daigo Makihara,
To identify differences in root plasticity patterns of two upland New Rice for Africa (NERICA) varieties, NERICA 1 and 4, in response to drought under conditions with contrasting soil profile characteristics, soil moisture gradients were imposed using a sloping bed system with depths ranging 30–65 cm and a line-source sprinkler system with a uniformly shallow soil layer of 20 cm depth. Varietal differences in shoot and root growths were identified only under moderate drought conditions, 11–18% v/ ...
Tópico(s): Plant nutrient uptake and metabolism
2016 - Taylor & Francis | Plant Production Science
Yuta Matsumura, Tomohiro Yamashita, Atsushi Sasaki, Eriko Nakata, Keita Kohno, Takahiro Masuda, Hidetoshi Tozaki‐Saitoh, Toshiyasu Imai, Yasushi Kuraishi, Makoto Tsuda, Kazuhide Inoue,
Accumulating evidence indicates that purinergic P2X4 receptors (P2X4R: cation channels activated by extracellular ATP) expressed in spinal microglia are crucial for pathological chronic pain caused by nerve damage, suggesting a potential target for drug discovery. We identified NP-1815-PX (5-[3-(5-thioxo-4H-[1,2,4]oxadiazol-3-yl)phenyl]-1H-naphtho[1, 2-b][1,4]diazepine-2,4(3H,5H)-dione) as a novel antagonist selective for P2X4R with high potency and selectivity compared with other P2XR subtypes. In ...
Tópico(s): Nerve injury and regeneration
2016 - Nature Portfolio | Scientific Reports
Toru Fujisawa, Hidetoshi Nakata, Masao Aizawa,
Tópico(s): Liquid Crystal Research Advancements
1998 - Institute of Electronics, Information and Communication Engineers | IEICE Transactions on Electronics
Seiji Nakata, Hidetoshi Yamanaka,
We analyzed mortality data (1973-84) associated with 19 major cancers in Japan. The standardized mortality ratio (SMR) for prostate cancer was high in prefectures clustered in the Kanto-Chubu and Kyusyu regions, and that for renal cancer was high in prefectures scattered over eastern Japan. On the other hand, the SMR for prostate cancer was low in prefectures in the Kinki and Shikoku regions. In males, the SMR for bladder cancer was low in the Kanto and Chubu regions, and that for renal cancer was ...
Tópico(s): Bladder and Urothelial Cancer Treatments
1994 - Wiley | International Journal of Urology
Keiji Terao, Daisuke Nakata, Hiroshi Fukumi, G. M. Schmid, Hidetoshi Arima, Fumitoshi Hirayama, Kaneto Uekama,
The objective of this study was to determine the effect of molecular encapsulation of coenzyme Q10 (CoQ10) by complexation with γ-cyclodextrin (γ-CD) (CoQ10-γ-CD) compared with a mixture of CoQ10 with microcrystalline cellulose (CoQ10-MCC) on absorption and bioavailability of CoQ10 in supplement form in healthy adults. Twenty-two volunteers received a single dose of a 150-mg capsule containing 30 mg CoQ10 under fasting conditions in an open-label, crossover design with a 2-week washout period. Blood ...
Tópico(s): Pharmaceutical studies and practices
2006 - Elsevier BV | Nutrition Research
Yousuke Kawahito, Yousuke Uemura, Yuichiro Doi, Masami Mizutani, Kouji Nishimoto, Hiroshi Kawakami, Manabu Tanaka, Hidetoshi Fujii, Kazuhiro Nakata, Seiji Katayama,
This research was performed with the objective of clarifying the effect of welding speed on melt flows during melt-run welding of SUS304 stainless steel plates with a 6-kW power laser beam on the basis of three-dimensional X-ray transmission in situ observation. As welding speed increased from 25 to 250 mm/s, three kinds of welds characterized by porosity formation and no defects or underfilling due to spatters were produced. The average and the maximum values of measured melt flow velocity were ...
Tópico(s): Hydrogen embrittlement and corrosion behaviors in metals
2016 - Taylor & Francis | Welding International
Yufeng Sun, Youngsu Ji, Hidetoshi Fujii, Kazuhiro Nakata, Kiyoshi Nogi,
Zr55Cu30Al10Ni5 bulk metallic glass (BMG) plate and pure copper plates with 2 mm in thickness were successfully joined by friction stir butt welding. Microstructure characterization revealed that a clear interface between the two materials was formed in the stir zone and no crystallization from the amorphous phase can be detected. On the copper side in the stir zone, a transitional microstructure of refined elongated grain structure, refined equiaxial grain structure and coarse equiaxial grain structure ...
Tópico(s): Metallic Glasses and Amorphous Alloys
2010 - Elsevier BV | Materials Science and Engineering A
K.H. Song, Hidetoshi Fujii, Kazuya Nakata,
In order to evaluate the properties of a friction stir welded Ni base alloy, Inconel 600 (single phase type) was selected. Sound friction stir welds without weld defect were obtained at 150 and 200 mm/min in welding speed, however, a groove like defect occurred at 250 mm/min. The electron back scattered diffraction (EBSD) method was used to analyze the grain boundary character distribution. As a result, dynamic recrystallization was observed at all conditions, and the grain refinement was achieved ...
Tópico(s): Aluminum Alloy Microstructure Properties
2009 - Elsevier BV | Materials & Design (1980-2015)
Kuk Hyun Song, Hidetoshi Fujii, Kazuhiro Nakata,
To evaluate the dynamic recrystallization aspect and microstructures, electron back scattered diffraction (EBSD) analysis on friction stir welded Inconel 600 was employed. Friction stir welding (FSW) led to the dynamic recrystallization in all conditions as high angle grain boundaries were distributed more than 85% in fraction, with equiaxed grains, and the grain refinement was accelerated from average grain size of 19 μm in the base material to 3.4 μm in the stir zone by increasing the welding speed. ...
Tópico(s): Aluminum Alloy Microstructure Properties
2009 - | MATERIALS TRANSACTIONS
Yuji Tokunaga, Takashi Ito, Hidetoshi Sugawara, Ryuji Nakata,
This Letter describes an efficient method for constructing a C3-symmetric [4]rotaxane through hydrogen bond-guided self-assembly and boroxine formation. The reactions proceed under mild conditions in solution, with entropically driven forces promoting the formation of the [4]rotaxane.
Tópico(s): Supramolecular Self-Assembly in Materials
2008 - Elsevier BV | Tetrahedron Letters
Nobuaki Ohtake, Motoaki Hatori, Hidetoshi Yamanaka, Seiji Nakata, Masaharu Sada, Takayuki Tsuji,
Familial prostate cancer has been studied in Europe and the United States. This study was conducted to clarify the clinical features and incidence of the human leukocyte antigen (HLA) in familial prostate cancer in patients seen at hospitals in Japan.The age at diagnosis, clinical stage, histologic differentiation, prognosis, cause of death and family history were compiled from 43 patients from 20 families with familial prostate cancer (group F) and compared in patients with sporadic prostate cancer ( ...
Tópico(s): Cancer-related molecular mechanisms research
1998 - Wiley | International Journal of Urology
K. Nogi, Yasuhiro Aoki, Hidetoshi Fujii, Kazuya Nakata,
In order to investigate the effect of gravity on the behavior of bubbles in a weld, gas tungsten arc (GTA) welding was performed with an argon–1% hydrogen mixed shielding gas both in a microgravity environment and in a terrestrial environment. The microgravity environment was produced for 10 s with less than 10−5 G by a drop-shaft type microgravity system. The material used was an aluminum alloy. By classifying pores into blowholes and wormholes with the shape factor of pores and comparing the results ...
Tópico(s): Mercury impact and mitigation studies
1998 - Elsevier BV | Acta Materialia
Seiji Nakata, Jin Satō, Kyoichi Imai, Hidetoshi Yamanaka, Yoshio Ichinose,
Prostate cancer is rare in Asia, but the number of patients is increasing in Japan. We conducted an epidemiological study of prostate cancer in Gunma Prefecture, Japan, to investigate the trends and characteristics of the disease.The subjects were 1,411 prostate cancer patients newly diagnosed between 1985 and 1992, and 656 patients who died from prostate cancer between 1981 and 1992. The incidence and mortality rates were calculated by year, demographic region and age.The yearly incidence rate ...
Tópico(s): Bladder and Urothelial Cancer Treatments
1995 - Wiley | International Journal of Urology
Kiyoshi Nogi, Yasuhiro Aoki, Hidetoshi Fujii, Kazuhiro Nakata, Shoichiro Kaihara,
In order to investigate the effect of gravity on the formation of a weld, gas tungsten arc (GTA) welding was performed both in a microgravity environment and in a terrestrial environment. The microgravity environment was produced for 10 sec with less than 10-5 G by a drop-shaft type microgravity system at Japan Microgravity Center (JAMIC). The material used was an aluminum alloy. It has become clear that in the microgravity environment, the weld bead is formed flatly and a large amount of metal can ...
Tópico(s): Gas Dynamics and Kinetic Theory
1998 - The Iron and Steel Institute of Japan | ISIJ International
Shaochuan Zhang, Bisei Ohkawara, Mikako Ito, Zhizhou Huang, Fei Zhao, Tomohiko Nakata, T Takeuchi, Hidetoshi Sakurai, Hirofumi Komaki, Masayoshi Kamon, Toshiyuki Araki, Kinji Ohno,
Abstract At the neuromuscular junction, the downstream of tyrosine kinase 7 (DOK7) enhances the phosphorylation of muscle-specific kinase (MuSK) and induces clustering of acetylcholine receptors (AChRs). We identified a patient with congenital myasthenic syndrome (CMS) with two heteroallelic mutations in DOK7, c.653-1G>C in intron 5 and c.190G>A predicting p.G64R in the pleckstrin homology domain. iPS cells established from the patient (CMS-iPSCs) showed that c.653-1G>C caused in- ...
Tópico(s): 3D Printing in Biomedical Research
2022 - Oxford University Press | Human Molecular Genetics