Enrique Canessa, Livio Tenze, Armando Pisani,
... discuss the implementation of this affordable technology in high schools (www.opendante.com), in pre-PhD diploma courses (www.ictp.tv) and at some universities in developing countries (www.dxd.tv).
Tópico(s): Multimedia Communication and Technology
2016 - De Gruyter | European Journal of Open Distance and E-Learning
J. Stacey Klutts, Steven B. Levery, Tamara L. Doering,
... with an N-linked glycosylation site and two DXD motifs. These latter motifs are believed to coordinate ... activity of glycosyltransferases. Site-directed mutagenesis of one DXD motif abolished Cxt1p activity, even though this activity ... all are conserved with respect to the essential DXD motif. These proteins represent a new family of ... with an N-linked glycosylation site and two DXD motifs. These latter motifs are believed to coordinate ... activity of glycosyltransferases. Site-directed mutagenesis of one DXD motif abolished Cxt1p activity, even though this activity ...
Tópico(s): Plant Pathogens and Fungal Diseases
2007 - Elsevier BV | Journal of Biological Chemistry
Premkumar Dinadayala, Davinder Kaur, Stefan Berg, Anita G. Amin, Varalakshmi Vissa, Delphi Chatterjee, Patrick J. Brennan, Dean C. Crick,
... integral membrane GTs (GT-C), that have modified DxD signatures in the first extracellular loop (22.Liu ...
Tópico(s): Carbohydrate Chemistry and Synthesis
2006 - Elsevier BV | Journal of Biological Chemistry
Nuno Borges, Joey D. Marugg, Nuno Empadinhas, Milton S. da Costa, Helena Santos,
... deduced amino acid sequence is also shown. The DXD motif common to several glycosyltransferase families is highlighted ...
Tópico(s): Enzyme Structure and Function
2004 - Elsevier BV | Journal of Biological Chemistry
Louis N. Gastinel, Christophe Bignon, A. Misra, Ole Hindsgaul, Joël H. Shaper, David H. Joziasse,
... exposed sequence D225VD227, which was identified as the DXD motif, known to be well conserved in many ...
Tópico(s): Glycosylation and Glycoproteins Research
2001 - Springer Nature | The EMBO Journal
Kohji Mori, Yoshihiro Nihei, Thomas Arzberger, Qihui Zhou, Ian R. Mackenzie, Andreas Hermann, Frank Hanisch, Frits Kamp, Brigitte Nuscher, Denise Orozco, Dieter Edbauer, Christian Haass,
... NLS). mCherry-fused hnRNPA3WT, its RNA binding mutant (DxD), and hnRNPA2 are almost completely nuclear. Scale bar, ...
Tópico(s): Neurogenetic and Muscular Disorders Research
2016 - Springer Nature | EMBO Reports
Αngeliki Andrikopoulou, Flora Zagouri, Kallirroi Goula, Dimitrios Haidopoulos, Nikolaos Thomakos, Anna Svarna, Meletios Α. Dimopoulos, Michalis Liontos,
... target in gynecological malignancies. Recently, Trastuzumab-Deruxtecan (T-DXd) has shown substantial efficacy in HER2 overexpressing carcinomas, ... patients. We have examined the efficacy of T-DXd in patients with metastatic endometrial, ovarian and cervical ... by immunohistochemistry (IHC) that were treated with T-DXd were retrospectively identified. Patients received T-DXd intravenously at a dose of 5.4 mg/ ... Results In total, 10 patients treated with T-DXd for recurrent/metastatic disease were identified. Regarding histology, ...
Tópico(s): Ovarian cancer diagnosis and treatment
2024 - BioMed Central | BMC Cancer
John R. Benson, Dorin Dumitru, Ismail Jatoi,
... K et al. Pharmacokinetics of trastuzumab deruxtecan (T-DXd), a novel anti-HER2 antibody-drug conjugate, in ...
Tópico(s): Cancer Genomics and Diagnostics
2021 - Future Medicine | Future Oncology