Produção Nacional
Revisado por pares
Rita Hilário de Carvalho, Ederson da Conceição Jesus, Vinício Oliosi Favero, Rosângela Straliotto, Adelson Paulo Araújo,
Tópico(s): Nematode management and characterization studies
2020 - Springer Science+Business Media | Journal of soil science and plant nutrition
Produção Nacional
Revisado por pares
Daniela Perroni Frias, Raquel Labiapari Nunes Gomes, Kelly Yoshizaki, Regiani Carvalho-Oliveira, Monique Matsuda, Mara de Souza Junqueira, Walcy Rosólia Teodoro, Pérola de Castro Vasconcellos, Daniela Pereira, Paulo Roberto da Conceição, Paulo Hilário Nascimento Saldiva, Thaís Mauad, Mariângela Macchione,
Abstract Diesel exhaust particles (DEP) are known to generate reactive oxygen species in the respiratory system, triggering cells to activate antioxidant defence mechanisms, such as Keap1-Nrf2 signalling and autophagy. The aim of this study was to investigate the relationship between the Keap1-Nrf2 signalling and autophagy pathways after DEP exposure. BEAS-2B cells were transfected with silencing RNA (siRNA) specific to Nrf2 and exposed to DEP. The relative levels of mRNA for Nrf2, NQO1, HO-1, LC3B, ...
Tópico(s): Genomics, phytochemicals, and oxidative stress
2020 - Nature Portfolio | Scientific Reports
Produção Nacional
Gisele Braziliano de Andrade, G. S. Montes, Gleice M.S. Conceição, Paulo Hilário Nascimento Saldiva,
The state of collagen aggregation in hepatic granulomas produced in experimental murine schistosomiasis and harvested at different phases of the disease was estimated by staining histological sections in Picrosirius and studying them under polarized light. Two different types of collagenous fibres appeared successively during granuloma evolution, the first population, of thin, weakly birefringent, greenish fibres being replaced by thicker collagen fibres which display a stronger yellow-red birefringence. ...
Tópico(s): Dermatological and Skeletal Disorders
1999 - Maney Publishing | Annals of Tropical Medicine and Parasitology
Produção Nacional
Revisado por pares
Mariana de Moura e Dias, Vinícius da Silva Duarte, Lúcio Flávio Macêdo Mota, Gabriela de Cássia Ávila Alpino, Sandra dos Reis Louzano, L. D. H. C. S. Da Conceição, Hilário Cuquetto Mantovani, Solange Silveira Pereira, Leandro Licursi de Oliveira, Talita Kesly Ferreira de Souza Mendes, Davide Porcellato, Maria do Carmo Gouveia Pelúzio,
Gut microbiota imbalance is associated with the occurrence of metabolic diseases such as obesity. Thus, its modulation is a promising strategy to restore gut microbiota and improve intestinal health in the obese. This paper examines the role of probiotics, antimicrobials, and diet in modulating gut microbiota and improving intestinal health. Accordingly, obesity was induced in C57BL/6J mice, after which they were redistributed and fed with an obesogenic diet (intervention A) or standard AIN-93 diet ( ...
Tópico(s): Clostridium difficile and Clostridium perfringens research
2023 - Multidisciplinary Digital Publishing Institute | Foods
Entrevistei Hilario Rosario da Conceicao em 2007. Encontrava-me nessa altura a meio de um projecto de doutoramento sobre Lourenco Marques. O ...
Tópico(s): Literature, Culture, and Criticism
2013 - ISCTE – Lisbon University Institute | Cadernos de Estudos Africanos
Produção Nacional
Revisado por pares
Marcos Abdo Arbex, György Böhm, Paulo Hilário Nascimento Saldiva, Gleice M.S. Conceição, Arden Pope, Alfésio Luı́s Ferreira Braga,
ABSTRACT This study was designed to evaluate the association between sugar cane plantation burning and hospital visits in Araraquara in the state of São Paulo, Brazil. From June 1 to August 31, 1995, the daily number of visits of patients who needed inhalation therapy in one of the main hospitals of the city was recorded and used as health impairment estimation. Sedimentation of particle mass (the amount of particles deposited on four containers filled with water) was measured daily. The association ...
Tópico(s): Air Quality and Health Impacts
2000 - Taylor & Francis | Journal of the Air & Waste Management Association
Produção Nacional
Revisado por pares
Sônia Cendon, Cláudia Naves Battlehner, Geraldo Lorenzi‐Filho, Marisa Dohlnikoff, Priscilla Maria Rodrigues Pereira, Gleice M.S. Conceição, Osvaldo Shigueomi Beppu, Paulo Hilário Nascimento Saldiva,
We describe a short time model for inducing experimental emphysema in rats by chronic tobacco smoke inhalation. Three groups of male Wistar rats (6 months old) were studied: controls (N = 8), rats intoxicated for 45 days (s-45, N = 7) or for 90 days (s-90, N = 8). The exposed animals were intoxicated 3 times a day (10 cigarettes per exposure period), 5 days a week. Pulmonary damage was assessed by means of functional tests and quantitative pathological examination of the airways and lung parenchyma. The s- ...
Tópico(s): Respiratory Support and Mechanisms
1997 - Associação Brasileira de Divulgação Científica | Brazilian Journal of Medical and Biological Research
Produção Nacional
Revisado por pares
Anna Cabral, Gleice M.S. Conceição, Paulo Hilário Nascimento Saldiva, Marco A. Martins,
Individual ability to perceive airway obstruction varies substantially. The factors influencing the perception of asthma are probably numerous and not well established in children. The present study was designed to examine the influence of asthma severity, use of preventive medication, age and gender on the association between respiratory symptoms (RS) and peak expiratory flow (PEF) rates in asthmatic children. We followed 92 asthmatic children, aged 6 to 16 years, for five months. Symptom scores ...
Tópico(s): Allergic Rhinitis and Sensitization
2002 - Associação Brasileira de Divulgação Científica | Brazilian Journal of Medical and Biological Research
Produção Nacional
Gisele Braziliano de Andrade, G. S. Montes, Gleice M.S. Conceição, Paulo Hilário Nascimento Saldiva,
The state of collagen aggregation in hepatic granulomas produced in experimental murine schistosomiasis and harvested at different phases of the disease was estimated by staining histological sections in Picrosirius and studying them under polarized light. Two different types of collagenous fibres appeared successively during granuloma evolution, the first population, of thin, weakly birefringent, greenish fibres being replaced by thicker collagen fibres which display a stronger yellow-red birefringence. ...
Tópico(s): Alkaline Phosphatase Research Studies
1999 - Maney Publishing | Annals of Tropical Medicine and Parasitology
Produção Nacional
Revisado por pares
Tatiane Mantovano, Leidiane Pereira Diniz, Eliezer de Oliveira da Conceição, Jonathan Rosa, Cláudia Cósta Bonecker, Dayani Bailly, José Hilário Delconte Ferreira, Thiago F. Rangel, Fábio Amodêo Lansac‐Tôha,
Tópico(s): Leech Biology and Applications
2020 - Springer Science+Business Media | Hydrobiologia
Produção Nacional
Revisado por pares
Fernando Korn Malerbi, Lourdes Conceição Martins, Paulo Hilário Nascimento Saldiva, Alfésio Luı́s Ferreira Braga,
Even though air pollutants exposure is associated with changes in the ocular surface and tear film, its relationship to the clinical course of blepharitis, a common eyelid disease, had not yet been investigated. Our objective was to investigate the correlation between air pollution and acute manifestations of blepharitis.We recorded all cases of changes in the eyelids and ocular surface, and rated clinical findings on a scale from zero (normal) to two (severe alterations). Daily values of carbon monoxide, ...
Tópico(s): Nasal Surgery and Airway Studies
2011 - Elsevier BV | Environmental Research
C Hoelz, Eva Negri, A.J.F.C. Lichtenfels, Gleice M.S. Conceição, Carmen Sílvia Valente Barbas, Paulo Hilário Nascimento Saldiva, Vera Luíza Capelozzi,
Tópico(s): Chronic Obstructive Pulmonary Disease (COPD) Research
2001 - Elsevier BV | Pathology - Research and Practice
Produção Nacional
Revisado por pares
Christiane Hoelz, Eva Negri, A.J.F.C. Lichtenfels, G CONCEICAO, Carmen Sílvia Valente Barbas, Paulo Hilário Nascimento Saldiva, Vera Luíza Capelozzi,
The present study was undertaken in order to describe the morphological differences between pulmonary lesions in acute respiratory distress syndrome originating from direct pulmonary injury (ARDSp) and those originating from extrapulmonary injury (ARDSexp). We investigated a total of 38 ARDS-patients (27 males) ranging in age from 19 to 75 years, classified according to underlying disease in pulmonary (ARDSp) and extrapulmonary disease (ARDSexp). The extent of acute diffuse alveolar damage was assessed ...
Tópico(s): Cardiac Arrest and Resuscitation
2001 - Elsevier BV | Pathology - Research and Practice
Produção Nacional
Revisado por pares
Suelem Missagia, Camila Alves Silva do Amaral, Alessandra Santos de Jesus, Marcos Abdo Arbex, Ubiratan de Paula Santos, Carmem Diva Saldiva de André, Paulo André, Paulo Hilário Nascimento Saldiva, Lourdes Conceição Martins, Alfésio Luı́s Ferreira Braga, Luiz Alberto Amador Pereira,
High particulate matter (PM10) concentrations are associated with increased incidence of respiratory symptoms and decreased lung function. This study evaluates the air pollution effects in children's and adolescents' lung function using peak expiratory flow (PEF) measurements over a given period, in an area exposed to industrial emissions.This was a panel study. The effects of air pollution on respiratory symptoms and PEF were investigated in 117 children and adolescents from three public schools ...
Tópico(s): Air Quality Monitoring and Forecasting
2018 - ASSOCIAÇÃO BRASILEIRA DE SAÚDE COLETIVA | Revista Brasileira de Epidemiologia
Produção Nacional
Revisado por pares
Sônia Cendon, Luiz Alberto Amador Pereira, Alfésio Luı́s Ferreira Braga, Gleice M.S. Conceição, A Cury, H Romaldini, Antônio Carlos Lopes, Paulo Hilário Nascimento Saldiva,
Myocardial infarction is an acute and severe cardiovascular disease that generally leads to patient admissions to intensive care units and few cases are initially admitted to infirmaries. The objective of the study was to assess whether estimates of air pollution effects on myocardial infarction morbidity are modified by the source of health information.The study was carried out in hospitals of the Brazilian Health System in the city of São Paulo, Southern Brazil. A time series study (1998-1999) ...
Tópico(s): Global Health Care Issues
2006 - UNIVERSIDADE DE SÃO PAULO | Revista de Saúde Pública
Produção Nacional
Revisado por pares
Marcos Abdo Arbex, Ubiratan de Paula Santos, Lourdes Conceição Martins, Paulo Hilário Nascimento Saldiva, Luiz Alberto Amador Pereira, Alfésio Luı́s Ferreira Braga,
A poluição atmosférica encontra-se presente nos mais diferentes cenários ao longo dos últimos 250 anos, desde que a Revolução Industrial acelerou o processo de emissão de poluentes que, até então, estava limitado ao uso doméstico de combustíveis vegetais e minerais e às emissões vulcânicas intermitentes. Hoje, aproximadamente 50% da população do planeta vivem em cidades e aglomerados urbanos e estão expostas a níveis progressivamente maiores de poluentes do ar. Este estudo é uma revisão não sistemática ...
Tópico(s): Energy and Environment Impacts
2012 - Sociedade Brasileira de Pneumologia e Tisiologia | Jornal Brasileiro de Pneumologia
Produção Nacional
Revisado por pares
Chin An Lin, Luiz Alberto Amador Pereira, Gleice Margarete de Souza Conceição, Humberto S. Kishi, Rodolfo Milani, Alfésio Luı́s Ferreira Braga, Paulo Hilário Nascimento Saldiva,
This study observed the relationship between air pollutants and ischemic cardiac diseases such as angina and acute myocardial infarction in a representative cardiovascular center emergency room in São Paulo, Brazil. Daily emergency room admissions to the Institute of the Heart of the University of São Paulo, as well as data concerning daily air pollutant levels and meteorological variables, were collected from January 1994 to August 1995. Generalized additive Poisson regressions were fitted to the ...
Tópico(s): Noise Effects and Management
2003 - Elsevier BV | Environmental Research
Produção Nacional
Revisado por pares
Tatiane Mantovano, Dayani Bailly, José Hilário Delconte Ferreira, Eliezer de Oliveira da Conceição, Fernanda A. S. Cassemiro, Ramiro de Campos, Roger Paulo Mormul, Thiago F. Rangel, Fábio Amodêo Lansac‐Tôha,
Abstract Climate change and species invasions pose serious threats to biodiversity. Daphnia lumholtzi Sars, 1885, a cladoceran species native to Africa, Asia, and Oceania, has successfully invaded large sections of North and South America, there is evidence that the increase in the Earth's temperature and the number of reservoirs have facilitated this process. In this context, our study evaluated the effects of climate change on the invasive potential of D. lumholtzi , identifying the environmental ...
Tópico(s): Aquatic Ecosystems and Biodiversity
2020 - Wiley | Freshwater Biology
Produção Nacional
Revisado por pares
Sylvia Costa Lima Farhat, Rodrigo Locatelli Pedro Paulo, Tomoko Shimoda, Gleice M.S. Conceição, Chin An Lin, Alfésio Luı́s Ferreira Braga, M.P.N. Warth, Paulo Hilário Nascimento Saldiva,
In order to assess the effect of air pollution on pediatric respiratory morbidity, we carried out a time series study using daily levels of PM10, SO2, NO2, ozone, and CO and daily numbers of pediatric respiratory emergency room visits and hospital admissions at the Children's Institute of the University of São Paulo Medical School, from August 1996 to August 1997. In this period there were 43,635 hospital emergency room visits, 4534 of which were due to lower respiratory tract disease. The total ...
Tópico(s): Global Health Care Issues
2005 - Associação Brasileira de Divulgação Científica | Brazilian Journal of Medical and Biological Research
Produção Nacional
Revisado por pares
Gleice Margarete de Souza Conceição, Paulo Hilário Nascimento Saldiva, Júlio M. Singer,
Este estudo, descreve e compara duas classes de modelos - os Modelos Lineares Generalizados (MLG) e os Modelos Aditivos Generalizados (MAG) - que podem ser utilizadas para avaliar a associação entre poluição atmosférica e marcadores de morbi-mortalidade. Enfoca os MAG como uma alternativa para a modelagem de relações não lineares não especificadas, e mostra que essa classe de modelos constitui uma boa opção para representar tanto a sazonalidade quanto a relação entre o desfecho e as variáveis meteorológicas. ...
Tópico(s): Air Quality Monitoring and Forecasting
2001 - ASSOCIAÇÃO BRASILEIRA DE SAÚDE COLETIVA | Revista Brasileira de Epidemiologia
Produção Nacional
Revisado por pares
Maluf Filho, Luiz Alberto Amador Pereira, Flávio F. Arbex, Marcos Abdo Arbex, Gleice Margarete de Souza Conceição, Ubiratan de Paula Santos, Antônio Carlos Lopes, Paulo Hilário Nascimento Saldiva, Alfésio Luı́s Ferreira Braga, Sônia Cendon,
Type 2 diabetes increases the risk of cardiovascular mortality and these patients, even without previous myocardial infarction, run the risk of fatal coronary heart disease similar to non-diabetic patients surviving myocardial infarction. There is evidence showing that particulate matter air pollution is associated with increases in cardiopulmonary morbidity and mortality. The present study was carried out to evaluate the effect of diabetes mellitus on the association of air pollution with cardiovascular ...
Tópico(s): COVID-19 impact on air quality
2008 - Associação Brasileira de Divulgação Científica | Brazilian Journal of Medical and Biological Research
Produção Nacional
Revisado por pares
Maria Eduarda Hilarino Drumond, Maria Cândida Trindade Costa de Seabra,
... características afins – os alunos da escola estadual “Professora Conceição Hilário” não estavam isentos da influência da construção de pressupostos.
Tópico(s): Science and Education Research
2020 - UNIVERSIDADE FEDERAL DO AMAPÁ | Letras Escreve
Produção Nacional
Revisado por pares
Lourdes Conceição Martins, Luiz Alberto Amador Pereira, Chin An Lin, Ubiratan de Paula Santos, Gildeoni Prioli, Olinda do Carmo Luiz, Paulo Hilário Nascimento Saldiva, Alfésio Luı́s Ferreira Braga,
To assess the lag structure between air pollution exposure and elderly cardiovascular diseases hospital admissions, by gender.Health data of people aged 64 years or older was stratified by gender in São Paulo city, Southeastern Brazil, from 1996 to 2001. Daily levels of air pollutants (CO, PM10, O3, NO2, and SO2) , minimum temperature, and relative humidity were also analyzed. It were fitted generalized additive Poisson regressions and used constrained distributed lag models adjusted for long time ...
Tópico(s): Global Health Care Issues
2006 - UNIVERSIDADE DE SÃO PAULO | Revista de Saúde Pública
Produção Nacional
Revisado por pares
Marcos Abdo Arbex, Gleice Margarete de Souza Conceição, Sônia Cendon, Flávio F. Arbex, Antônio Carlos Lopes, E P Moyses, Silvia Leticia Santiago, Paulo Hilário Nascimento Saldiva, Luiz Alberto Amador Pereira, Alfésio Luı́s Ferreira Braga,
Background: Patients with chronic obstructive pulmonary disease (COPD) can have recurrent disease exacerbations triggered by several factors, including air pollution. Visits to the emergency respiratory department can be a direct result of short-term exposure to air pollution. The aim of this study was to investigate the relationship between the daily number of COPD emergency department visits and the daily environmental air concentrations of PM 10 , SO 2 , NO 2 , CO and O 3 in the City of São Paulo, Brazil. Methods: ...
Tópico(s): Noise Effects and Management
2009 - BMJ | Journal of Epidemiology & Community Health
Produção Nacional
Revisado por pares
Marcos Abdo Arbex, Lourdes Conceição Martins, Luiz Alberto Amador Pereira, Fernanda Negrini, Arnaldo Alves Cardoso, Wanessa R. Melchert, R.F. Arbex, Paulo Hilário Nascimento Saldiva, Antonella Zanobetti, Alfésio Luı́s Ferreira Braga,
Studies of cooking-generated NO2 effects are rare in occupational epidemiology. In the present study, we evaluated the lung function of professional cooks exposed to NO2 in hospital kitchens. We performed spirometry in 37 cooks working in four hospital kitchens and estimated the predicted FVC, FEV1 and FEF(25-75), based on age, sex, race, weight, and height, according to Knudson standards. NO2 measurements were obtained for 4 consecutive days during 4 different periods at 20-day intervals in each ...
Tópico(s): Indoor Air Quality and Microbial Exposure
2007 - Associação Brasileira de Divulgação Científica | Brazilian Journal of Medical and Biological Research
Produção Nacional
Revisado por pares
Fabiana Nitz, Bruna Oliveira de Melo, Luís Cláudio Nascimento da Silva, Andrea de Souza Monteiro, Sirlei Garcia Marques, Valério Monteiro‐Neto, Rosimary de Jesus Gomes Turri, Antônio Dantas Silva, Patrícia Cristina Ribeiro Conceição, Hilário José Cardoso Magalhães, Adrielle Zagmignan, Thiago Azevedo Feitosa Ferro, Maria Rosa Quaresma Bomfim,
Pseudomonas aeruginosa has caused high rates of mortality due to the appearance of strains with multidrug resistance (MDR) profiles. This study aimed to characterize the molecular profile of virulence and resistance genes in 99 isolates of P. aeruginosa recovered from different clinical specimens. The isolates were identified by the automated method Vitek2, and the antibiotic susceptibility profile was determined using different classes of antimicrobials. The genomic DNA was extracted and amplified ...
Tópico(s): Pharmaceutical and Antibiotic Environmental Impacts
2021 - Multidisciplinary Digital Publishing Institute | Microorganisms
Produção Nacional
Revisado por pares
Eliezer de Oliveira da Conceição, Jéssica Magon Garcia, Gustavo Henrique Zaia Alves, Driele Delanira-Santos, Daiany de Fátima Corbetta, Tânia Camila Crivelari Betiol, Ricardo Pacífico, Mariza Barion Romagnolo, Valéria Flávia Batista da Silva, Dayani Bailly, José Hilário Delconte Ferreira, Edivando Vítor do Couto,
Brazilian biodiversity is undergoing numerous attacks and misguided policies that aim to reduce protected areas (PAs) with the main argument of expanding agribusiness to improve the country's economic performance. An example is the draft law (DL) 527/2016, which aimed to reduce approximately 70% of the Devonian Escarpment Environmental Protection Area (DEEPA), a large PA in southern Brazil, hosts two biodiversity hotspot biomes. This study shows the possible downsizing damages to biodiversity and landscape ...
Tópico(s): Economic and Environmental Valuation
2021 - Elsevier BV | Land Use Policy
Produção Nacional
Revisado por pares
Eliezer de Oliviera da Conceição, Tatiane Mantovano, Ramiro de Campos, Edivando Vítor do Couto, José Hilário Delconte Ferreira, Thiago F. Rangel, Koen Martens, Dayani Bailly, Janet Higuti,
Tópico(s): Subterranean biodiversity and taxonomy
2023 - Springer Science+Business Media | Hydrobiologia
Produção Nacional
Maria Eduarda Bezerra do Nascimento, Ana Beatriz Oliveira de Melo, Elter Alves Faria, Alysson Fellipe Alves de Souza, Marcos Antonio da Conceição, A. Hilario, Marcos Antônio Souto Maior Neto, Marinalva Martins dos Santos, Leny Norder Spoladori, Paulo Henrique Costa Pires, J.F. de Lima, David F. Silva,
A Esclerose Lateral Amiotrófica (ELA) é uma doença neurodegenerativa progressiva e fatal que compromete os neurônios motores responsáveis pelo controle dos músculos voluntários. Os avanços na pesquisa têm contribuído para uma melhor compreensão dos mecanismos subjacentes à doença, incluindo fatores genéticos, celulares e moleculares que influenciam seu desenvolvimento e progressão. O diagnóstico da ELA ainda apresenta desafios, e biomarcadores emergentes, como proteínas específicas no líquido cefalorraquidiano ...
Tópico(s): Neurogenetic and Muscular Disorders Research
2024 - | Brazilian Journal of Implantology and Health Sciences
Kaoany Ferreira da Silva, Rita Hilário de Carvalho, Luan Valladares dos Santos França Ferreira, Adelson Paulo Araújo, Ederson da Conceição Jesus,
Tópico(s): Plant pathogens and resistance mechanisms
2024 - Editora da Universidade Estadual de Maringá (Eduem) | Acta Scientiarum Agronomy