Richard J. Agnello, Lawrence P. Donnelley,
... https://doi.org/10.3389/fmars.2020.00053Yutaro Sakai, Hiroki Wakamatsu, Tsutom Miyata , Aquaculture Economics & Management 23, no. ... https://doi.org/10.1080/13657305.2018.1466934Yutaro Sakai, Hiroki Wakamatsu, Tsutom Miyata Impact of the Great East ...
Tópico(s): Sustainable Industrial Ecology
1975 - University of Chicago Press | The Journal of Law and Economics
Shigeyuki Yamashita, Tokiko Suzuki, Keisuke Iguchi, Takuya Sakamoto, Kengo Tomita, Hiroki Yokoo, Mari Sakai, Hiroki Misawa, Kohshi Hattori, Toshi Nagata, Yasuhide Watanabe, Naoyuki Matsuda, Naoki Yoshimura, Yuichi Hattori,
Tópico(s): Mechanical Circulatory Support Devices
2018 - Springer Science+Business Media | Naunyn-Schmiedeberg s Archives of Pharmacology
Munetoshi Sakai, Hiroki Kono, Akira Nakajima, Hideki Sakai, Masahiko Abe, Akira Fujishima,
On a superhydrophobic surface, the internal fluidity of water droplets with different volumes (15, 30 microL) and their horizontal motion in an external electric field were evaluated using particle image velocimetry (PIV). For driving of water droplets on a superhydrophobic coating between parallel electrodes, it was important to place them at appropriate positions. Droplets moved with slipping. Small droplets showed deformation that is more remarkable. Results show that the dielectrophoretic force ...
Tópico(s): Electrohydrodynamics and Fluid Dynamics
2009 - American Chemical Society | Langmuir
Munetoshi Sakai, Hiroki Kono, Akira Nakajima, Xintong Zhang, Hideki Sakai, Masahiko Abe, Akira Fujishima,
In this study, we prepared various superhydrophobic surfaces using ZnO nanorod arrays (ZnO-NR) of different diameters. The contact angle was equivalent to the calculated value if it is assuming that the topmost surface of the rods is a solid-liquid contact area. On the superhydrophobic ZnO-NR surfaces, the 5 microL water droplets slid down by constant acceleration motion. Sliding acceleration was governed by the solid area fraction. The resistance force of the actual measurement was consistent with ...
Tópico(s): Fluid Dynamics and Heat Transfer
2009 - American Chemical Society | Langmuir
Tomoharu Ohta, Kosuke Sakai, Hiroki Taniguchi, Benjamin Driesen, Yoshinori Okada, Kensuke Kobayashi, Yasuhiro Niimi,
We have fabricated thin films of a van der Waals (vdW) ferromagnetic metal Fe5GeTe2 and characterized them by measuring the anomalous Hall effect. While the bulk Fe5GeTe2 does not exhibit a perpendicular magnetic anisotropy (PMA) unlike Fe3GeTe2, PMA emerges in the thin film devices. Furthermore, the PMA is enhanced with decreasing thickness of Fe5GeTe2. In particular, a thin film (5 unit-cell layer) device fabricated with Fe5GeTe2 quenched at 1050 K has two times larger coercive field than that prepared ...
Tópico(s): Graphene research and applications
2020 - Institute of Physics | Applied Physics Express
K Sakai, Hiroki Kawada, Osamu Takamatsu, Hiro Matsuda, Ken Eguchi, T. Nakagiri,
Abstract Electrical memory switching has been observed in the metal/Langmuir-Blodgett (LB) film/metal sandwich structure with a noble metal base electrode. Switching from a non-conducting OFF state to a conducting ON state (WRITE operation) and/or switching back to the OFF state (ERASE) are/is possible by applying adequate voltage; however, when the voltage is reduced, both OFF and ON states remain the same. A memory system utilizing an LB film and a scanning tunnelling microscope, has been proposed.
Tópico(s): Electrochemical Analysis and Applications
1989 - Elsevier BV | Thin Solid Films
Hiroyuki Imachi, Sanae Sakai, Hiroki Nagai, Takashi Yamaguchi, Ken Takai,
A novel methane-producing archaeon, designated strain HASUT, was isolated from a lotus field. Cells were Gram-negative, non-motile, irregular cocci, 2–3 μm in diameter, and occurred singly. Growth was observed at 15–40 °C (optimum, 37 °C) and pH 6.5–7.5 (optimum, pH 7.0). The G+C content of the genomic DNA was 60.9 mol%. Strain HASUT utilized ethanol, 1-propanol, 1-butanol, hydrogen and formate for growth and methane production. It converted ethanol to methane and acetate. Based on comparative 16S rRNA ...
Tópico(s): Genomics and Phylogenetic Studies
2009 - Microbiology Society | INTERNATIONAL JOURNAL OF SYSTEMATIC AND EVOLUTIONARY MICROBIOLOGY
Ryuichi Sakai, Hiroki Matsubara, Keiko Shimamoto, M. Jimbo, Hisao Kamiya, Michio Namikoshi,
The bioassay-guided fractionation of the water-soluble extract of the marine sponge Cribrochalina olemda collected in Palau resulted in the isolation of a new amino acid cribronic acid (1): (2S,4R,5R)-5-hydroxy-4-sulfooxypiperidine-2-carboxylic acid. However, aqueous extracts of Stylotella aurantium and Axinella carteri collected in Yap State, Micronesia, afforded a known N-methyl-d-aspartic acid (NMDA)-type glutamate receptor agonist, (2S,4S)-4-sulfooxypiperidine-2-carboxylic acid (2), as a common active ...
Tópico(s): Ion channel regulation and function
2003 - American Chemical Society | Journal of Natural Products
Takashi Uchiyama, Hirokazu Takahashi, Michiko Sugiyama, Eiji Sakai, Hiroki Endo, Kunihiro Hosono, Kyoko Yoneda, Masato Yoneda, Masahiko Inamori, Yoji Nagashima, Yoshiaki Inayama, Koichiro Wada, Atsushi Nakajima,
The possible role of leptin in colorectal tumors has been investigated in previous studies; however, to date, the conclusions remain under debate. Therefore, we investigated the serum leptin levels in colorectal adenoma patients. In addition, expression of the leptin receptor, and the leptin receptor-mediated signaling pathways were investigated in biopsy specimens collected from human patients with colorectal adenoma. No significant difference in the mean serum leptin level was observed between ...
Tópico(s): Biochemical Analysis and Sensing Techniques
2010 - Wiley | Cancer Science
Hirokazu Takahashi, Kunihiro Hosono, Takashi Uchiyama, Michiko Sugiyama, Eiji Sakai, Hiroki Endo, Shin Maeda, Katherine L. Schaefer, Hitoshi Nakagama, Atsushi Nakajima,
Activating synthetic ligands for peroxisome proliferator-activated receptor gamma (PPARgamma), such as pioglitazone, are commonly used to treat persons with diabetes mellitus with improvement of insulin resistance. Several reports have clearly demonstrated that PPARgamma ligands could inhibit colorectal cancer cell growth and induce apoptosis. Meanwhile, aberrant crypt foci (ACF) have come to be established as a biomarker of the risk of CRC in azoxymethane-treated mice and rats. In humans, ACF can ...
Tópico(s): Cancer, Lipids, and Metabolism
2010 - Hindawi Publishing Corporation | PPAR Research
Masahiro Sonoshita, Masahiro Aoki, Haruhiko Fuwa, Koji Aoki, Hisahiro Hosogi, Yoshiharu Sakai, Hiroki Hashida, Arimichi Takabayashi, Makoto Sasaki, Sylvie Robine, Kazuyuki Itoh, Kiyoko Yoshioka, Fumihiko Kakizaki, Takanori Kitamura, Masanobu Oshima, Makoto M. Taketo,
Summary Metastasis is responsible for most cancer deaths. Here, we show that Aes (or Grg5 ) gene functions as an endogenous metastasis suppressor. Expression of Aes was decreased in liver metastases compared with primary colon tumors in both mice and humans. Aes inhibited Notch signaling by converting active Rbpj transcription complexes into repression complexes on insoluble nuclear matrix. In tumor cells, Notch signaling was triggered by ligands on adjoining blood vessels, and stimulated transendothelial ...
Tópico(s): Epigenetics and DNA Methylation
2011 - Cell Press | Cancer Cell
We investigate the $S=1/2$ quantum spin antiferromagnets on the triangular and Kagome lattices in magnetic field, using the numerical exact diagonalization. Particularly we focus on an anomalous magnetization behavior of each system at 1/3 of the saturation magnetization. The critical exponent analyses suggest that it is a conventional magnetization plateau on the triangular lattice, while an unconventional phenomenon, called the magnetization ramp, on the Kagome lattice.
Tópico(s): Organic and Molecular Conductors Research
2011 - American Physical Society | Physical Review B
Eiji Sakai, Hiroki Endo, Leo Taniguchi, Yasuo Hata, Akiko Ezuka, Hajime Nagase, Eiji Yamada, Hidenori Ohkubo, Takuma Higurashi, Yusuke Sekino, Tomoko Koide, Hiroshi Iida, Kunihiro Hosono, Takashi Nonaka, Hirokazu Takahashi, Masahiko Inamori, Shin Maeda, Atsushi Nakajima,
Aim To identify the predictive factors for the presence of small bowel lesions in patients with obscure gastrointestinal bleeding ( OGIB ). Methods A total of 242 patients with OGIB (overt 149: occult 93) were retrospectively included in the present study. Capsule endoscopy ( CE ) was carried out to investigate the small bowel, and detected lesions were classified according to the P0 ‐ P2 system. Only P2 lesions were defined as significant lesions. Univariate and multivariate logistic regression analyses were ...
Tópico(s): Platelet Disorders and Treatments
2012 - Wiley | Digestive Endoscopy
Masanori Sakai, Hiroki Iguma, Katsufumi Kondo, Tetsuya Aizawa,
Tópico(s): Biodiesel Production and Applications
2012 - | SAE technical papers on CD-ROM/SAE technical paper series
Tae YAMASHITA, Hisaya Hiramatsu, Naoto Sakai, Hiroki Namba,
A 37-year-old man with C4-5 spinal cord injury (SCI) presented with abnormally high blood pressure after vesicocutaneous catheter exchange and was treated with antihypertensive agents. Two weeks later, he developed headache and visual disturbance, and presented with fluctuating blood pressure. Multiple subcortical hemorrhages in the left occipital and right frontal lobes occurred on the next day, and he died of increased intracranial pressure 3 weeks later. Based on the symptoms and computed tomography ...
Tópico(s): Spinal Dysraphism and Malformations
2012 - Japan Neurological Society | Neurologia medico-chirurgica
Eiji Sakai, Hiroki Endo, Shingo Kato, Tetsuya Matsuura, Wataru Tomeno, Leo Taniguchi, Takashi Uchiyama, Yasuo Hata, Eiji Yamada, Hidenori Ohkubo, Takuma Higrashi, Kunihiro Hosono, Hirokazu Takahashi, Atsushi Nakajima,
Abstract Background Capsule endoscopy with flexible spectral imaging color enhancement (CE-FICE) has been reported to improve the visualization and detection of small-bowel lesions, however, its clinical usefulness is still not established. Therefore, we conducted a study to evaluate whether CE-FICE contributes to improve the detectability of small-bowel lesions by CE trainees. Methods Four gastroenterology trainees without prior CE experience were asked to read and interpret 12 CE videos. Each of ...
Tópico(s): Esophageal and GI Pathology
2012 - BioMed Central | BMC Gastroenterology
Ayako Sakai, Hiroki Tanaka, Yoshiko Konishi, Ryo Hanazawa, Toshiko OTA, Yoshiyuki Nakahara, Shoji Sekiguchi, Emi OSHIDA, Masahiko Takino, Masakatsu Ichinoe, Kunie Yoshikawa, Takumi YOSHIZAWA, Kosuke Takatori,
平成14年産(前年産)市販玄米100検体と平成13年産政府保有備蓄玄米15検体の真菌フローラを平成15年4~6月に試験した.前年産米では,真菌が着生している米粒の割合が 20% 以下の検体が大部分であったが,備蓄米では好乾性真菌が 80% 以上の米粒に着生している検体が半数を超えた.前年産米に着生していた真菌は,Penicillium, Alternaria 属のものが多く,備蓄米では,Aspergillus, Penicillium, Eurotium 属のものが多かった.マイコトキシン関連真菌として P. islandicum, A. versi-color, A. ochraceus などを分離した.P. islandicum は,国産米から分離されることは珍しいとされるが,3検体から分離され,うち1検体では 82% の米粒から検出された.HPLCの結果から分離した P. islandicum は,すべてルテオスカイリンを産生する可能性があることが示唆された.
Tópico(s): Plant Pathogens and Fungal Diseases
2005 - Japanese Society for Food Hygiene and Safety | Food Hygiene and Safety Science (Shokuhin Eiseigaku Zasshi)
Shinji Sakai, Hiroki Masuhara, Yusuke Yamada, Tsutomu Ono, Hiroyuki Ijima, Koei Kawakami,
The rupture forces of porous alginate scaffolds seeded with hepatocytes or fibroblast-like cells increased during 3 d of culture and then decreased. The phenomenon was independent of the number of viable cells within the scaffolds, but dependent on protein adsorption to the alginate as well as a reduction in the degree of crosslinks of the calcium-alginate gel.
Tópico(s): Bone Tissue Engineering Materials
2005 - Elsevier BV | Journal of Bioscience and Bioengineering
Yi Zhou, Kouji Nagata, Yasuhiko Sakai, Hiroki Suzuki, Y. Ito, Osamu TERASHIMA, Toshiyuki Hayase,
In this paper, direct numerical simulations are carried out to study single-square grid-generated turbulence at a Reynolds number \documentclass[12pt]{minimal}\begin{document}$Re_{L_0}$\end{document}ReL0 = 20 000 (based on the inlet velocity Uin and the length of grid bar L0). Different from the regular grid and the multiscale/fractal grid, here only single large square grid is placed at the center near the inlet. First, we investigate the evolutions of turbulence characteristics (e.g., mean streamwise ...
Tópico(s): Fluid Dynamics and Vibration Analysis
2014 - American Institute of Physics | Physics of Fluids
Eiji Sakai, Hiroki Endo, Masataka Taguri, Harunobu Kawamura, Leo Taniguchi, Yasuo Hata, Akiko Ezuka, Hajime Nagase, Takaomi Kessoku, Ken Ishii, Jun Arimoto, Eiji Yamada, Hidenori Ohkubo, Takuma Higurashi, Tomoko Koide, Takashi Nonaka, Hirokazu Takahashi, Atsushi Nakajima,
Small bowel angioectasia is reported as the most common cause of bleeding in patients with obscure gastrointestinal bleeding. Although the safety and efficacy of endoscopic treatment have been demonstrated, rebleeding rates are relatively high. To establish therapeutic and follow-up guidelines, we investigated the long-term outcomes and clinical predictors of rebleeding in patients with small bowel angioectasia.A total of 68 patients were retrospectively included in this study. All the patients ...
Tópico(s): Esophageal and GI Pathology
2014 - BioMed Central | BMC Gastroenterology
Kentaro Iwata, Asako Doi, Takahiko Fukuchi, Goh Ohji, Yuko Shirota, Tetsuya Sakai, Hiroki Kagawa,
Although it has received a degree of notoriety as a cause for antibiotic-associated enterocolitis (AAE), the role of methicillin resistant Staphylococcus aureus (MRSA) in the pathogenesis of this disease remains enigmatic despite a multitude of efforts, and previous studies have failed to conclude whether MRSA can cause AAE. Numerous cases of AAE caused by MRSA have been reported from Japan; however, due to the fact that these reports were written in the Japanese language and a good portion lacked ...
Tópico(s): Antimicrobial Resistance in Staphylococcus
2014 - BioMed Central | BMC Infectious Diseases
Yi Zhou, Kouji Nagata, Yasuhiko Sakai, Hiroki Suzuki, Y. Ito, Osamu TERASHIMA, Toshiyuki Hayase,
Direct numerical simulations were carried out to study the turbulence generated by a fractal square grid at a Reynolds number of \documentclass[12pt]{minimal}\begin{document}$Re_{L_0}$\end{document}ReL0 = 20000 (based on the inlet velocity Uin and length of the largest grid bar L0). We found that in the near-field region, the fractal square grid can generate much higher turbulence levels and has a better mixing performance than the single square grid. However, the current numerical results show that ...
Tópico(s): Fluid Dynamics and Vibration Analysis
2014 - American Institute of Physics | Physics of Fluids
Alistair R. R. Forrest, Hideya Kawaji, Michael Rehli, J. Kenneth Baillie, Michiel de Hoon, Vanja Haberle, Timo Lassmann, Ivan V. Kulakovskiy, Marina Lizio, Masayoshi Itoh, Robin Andersson, Chris Mungall, Terrence F. Meehan, Sebastian Schmeier, Nicolas Bertin, Mette Jørgensen, Emmanuel Dimont, Peter Arner, Christian Schmidl, Ulf Schaefer, Yulia A. Medvedeva, Charles Plessy, Morana Vitezic, Jessica Severin, Colin A. Semple, Yuri Ishizu, Robert S. Young, Margherita Francescatto, Intikhab Álam, Davide Albanese, Gabriel M. Altschule, Takahiro Arakawa, John A. C. Archer, Peter Arner, Magda Babina, Sarah Rennie, Piotr J. Balwierz, Anthony G Beckhouse, Swati Pradhan-Bhatt, Judith A. Blake, Antje Blumenthal, Beatrice Bodega, Alessandro Bonetti, James Briggs, Frank Brombacher, A. Maxwell Burroughs, Andrea Califano, Carlo Vittorio Cannistraci, Daniel Carbajo, Yun Chen, Marco Chierici, Yari Ciani, Hans Clevers, Emiliano Dalla, Carrie Davis, Michael Detmar, Alexander D. Diehl, Taeko Dohi, Finn Drabløs, Albert S.B. Edge, Matthias Edinger, Karl Ekwall, Mitsuhiro Endoh, Hideki Enomoto, Michela Fagiolini, Lynsey Fairbairn, Hai Fang, Mary C. Farach‐Carson, Geoffrey J. Faulkner, Alexander V. Favorov, Malcolm E Fisher, Martin C. Frith, Rie Fujita, Shiro Fukuda, Cesare Furlanello, Masaaki Furuno, Jun Furusawa, Teunis B. H. Geijtenbeek, Andrew P. Gibson, T Gingeras, Dan Goldowitz, Julian Gough, Sven Guhl, Reto Guler, Stefano Gustincich, Thomas J Ha, Masahide Hamaguchi, Mitsuko Hara, Matthias Harbers, Jayson Harshbarger, Akira Hasegawa, Yuki Hasegawa, Takehiro Hashimoto, Meenhard Herlyn, Kelly J Hitchens, Shannan J. Ho Sui, Oliver Hofmann, Ilka Hoof, Fumi Hori, Łukasz Huminiecki, Kei Iida, Tomokatsu Ikawa, Boris R. Janković, Hui Jia, Anagha Joshi, Giuseppe Jurman, Bogumił Kaczkowski, Chieko Kai, Kaoru Kaida, Ai Kaiho, Kazuhiro Kajiyama, Mutsumi Kanamori-Katayama, Artem S. Kasianov, Takeya Kasukawa, Shintaro Katayama, Sachi Kato, Shuji Kawaguchi, Hiroshi Kawamoto, Yuki I. Kawamura, Tsugumi Kawashima, Judith Kempfle, Tony Kenna, Juha Kere, Levon M. Khachigian, Toshio Kitamura, S. Peter Klinken, Alan J. Knox, Miki Kojima, Soichi Kojima, Naoto Kondo, Haruhiko Koseki, Shigeo Koyasu, Sarah Krampitz, Atsutaka Kubosaki, Andrew T. Kwon, Jeroen F. J. Laros, Weon-Ju Lee, Andreas Lennartsson, Kang Li, Berit Lilje, Leonard Lipovich, Alan Mackay‐Sim, R Manabe, Jessica C. Mar, Benoı̂t Marchand, Anthony Mathelier, Niklas Mejhert, Alison Meynert, Yosuke Mizuno, David Morais, Hiromasa Morikawa, Mitsuru Morimoto, Kazuyo Moro, Efthymios Motakis, Hozumi Motohashi, Christine L. Mummery, Mitsuyoshi Murata, Sayaka Nagao-Sato, Yutaka Nakachi, Fumio Nakahara, Toshiyuki Nakamura, Yukio Nakamura, Kenichi Nakazato, Erik van Nimwegen, Noriko Ninomiya, Hiromi Nishiyori, Shohei Noma, Tadasuke Nozaki, Soichi Ogishima, Naganari Ohkura, Hiroko Ohmiya, Hiroshi Ohno, Mitsuhiro Ohshima, Mariko Okada, Yasushi Okazaki, Valerio Orlando, Dmitry A. Ovchinnikov, Arnab Pain, Robert Passier, Margaret Patrikakis, Helena Persson, Silvano Piazza, James Prendergast, Owen J. L. Rackham, Jordan A. Ramilowski, Mamoon Rashid, Timothy Ravasi, Patrizia Rizzu, Marco Roncador, Sugata Roy, Morten Beck Rye, Eri Saijyo, Antti Sajantila, Akiko Saka, Shimon Sakaguchi, Mizuho Sakai, Hiroki Sato, Hironori Satoh, Suzana Savvi, Alka Saxena, Claudio Schneider, Erik Schultes, Gundula Schulze‐Tanzil, Anita Schwegmann, Thierry Sengstag, Guojun Sheng, Hisashi Shimoji, Yishai Shimoni, Jay W. Shin, Christophe Simon, Daisuke Sugiyama, Takaaki Sugiyama, Masanori Suzuki, Naoko Suzuki, Rolf Swoboda, Peter A.C. ‘t Hoen, Michihira Tagami, Naoko Takahashi Tagami, Jun Takai, Hiroshi Tanaka, Hideki Tatsukawa, Zuotian Tatum, Mark Thompson, Hiroo Toyoda, Tetsuro Toyoda, Eivind Valen, Marc van de Wetering, Linda Berg, Roberto Verardo, Dipti Vijayan, Ilya E. Vorontsov, Wyeth W. Wasserman, Shoko Watanabe, Christine A. Wells, Louise N Winteringham, Ernst J. Wolvetang, Emily J. Wood, Yoko Yamaguchi, Masayuki Yamamoto, Misako Yoneda, Yohei Yonekura, Shigehiro Yoshida, Susan E. Zabierowski, Peter Zhang, Xiaobei Zhao, S. Zucchelli, Kim Summers, Harukazu Suzuki, Carsten O. Daub, Jun Kawai, Peter Heutink, Yoshihide Hayashizaki, Tom C. Freeman, Boris Lenhard, Vladimir B. Bajić, Martin S. Taylor, Vsevolod J. Makeev, Albin Sandelin, David Hume, Piero Carninci, Yoshihide Hayashizaki,
Regulated transcription controls the diversity, developmental pathways and spatial organization of the hundreds of cell types that make up a mammal. Using single-molecule cDNA sequencing, we mapped transcription start sites (TSSs) and their usage in human and mouse primary cells, cell lines and tissues to produce a comprehensive overview of mammalian gene expression across the human body. We find that few genes are truly ‘housekeeping’, whereas many mammalian promoters are composite entities composed ...
Tópico(s): RNA modifications and cancer
2014 - Nature Portfolio | Nature
Asako Matsushima, Yuich Kuroki, Shinji Nakajima, Tomohiko Sakai, Hiroki Kojima, Masashi Ueyama,
Toxic shock syndrome (TSS) caused by methicillin-resistant Staphylococcus aureus (MRSA) nosocomial infection is a growing concern in both adult and pediatric patients. The reason why TSS appears in only some patients with MRSA infection remains unclear. In this study, we analyzed serial TSS toxin-1 (TSST-1) antibody in patients with burn injury to investigate the mechanisms of TSS caused by MRSA nosocomial infection. This study comprised of patients with burn injury in our burn care unit from September, ...
Tópico(s): Nosocomial Infections in ICU
2014 - Oxford University Press | Journal of Burn Care & Research
Hiromasa Morikawa, Naganari Ohkura, Alexis Vandenbon, Masayoshi Itoh, Sayaka Nagao-Sato, Hideya Kawaji, Timo Lassmann, Piero Carninci, Yoshihide Hayashizaki, Alistair R. R. Forrest, Daron M. Standley, Hiroshi Date, Shimon Sakaguchi, Alistair R. R. Forrest, Hideya Kawaji, Michael Rehli, J. Kenneth Baillie, Michiel de Hoon, Vanja Haberle, Timo Lassmann, Ivan V. Kulakovskiy, Marina Lizio, Masayoshi Itoh, Robin Andersson, Chris Mungall, Terrence F. Meehan, Sebastian Schmeier, Nicolas Bertin, Mette Jørgensen, Emmanuel Dimont, Peter Arner, Christian Schmidl, Ulf Schaefer, Yulia A. Medvedeva, Charles Plessy, Morana Vitezic, Jessica Severin, Colin A. Semple, Yuri Ishizu, Margherita Francescatto, Intikhab Alam, Davide Albanese, Gabriel Altschuler, John A. C. Archer, Peter Arner, Magda Babina, Sarah Baker, Piotr J. Balwierz, Anthony G Beckhouse, Swati Pradhan-Bhatt, Judith A. Blake, Antje Blumenthal, Beatrice Bodega, Alessandro Bonetti, James Briggs, Frank Brombacher, A. Maxwell Burroughs, Andrea Califano, Carlo Vittorio Cannistraci, Daniel Carbajo, Yun Chen, Marco Chierici, Yari Ciani, Hans Clevers, Emiliano Dalla, Carrie Davis, Bart Deplancke, Michael Detmar, Alexander D. Diehl, Taeko Dohi, Finn Drabløs, Albert S.B. Edge, Matthias Edinger, Karl Ekwall, Mitsuhiro Endoh, Hideki Enomoto, Michela Fagiolini, Lynsey Fairbairn, Hai Fang, Mary C. Farach‐Carson, Geoffrey J. Faulkner, Alexander V. Favorov, Malcolm E Fisher, Martin C. Frith, Rie Fujita, Shiro Fukuda, Cesare Furlanello, Masaaki Furuno, Jun-ichi Furusawa, Teunis B. H. Geijtenbeek, Andrew Gibson, T Gingeras, Dan Goldowitz, Julian Gough, Sven Guhl, Reto Guler, Stefano Gustincich, Thomas J Ha, Masahide Hamaguchi, Mitsuko Hara, Matthias Harbers, Jayson Harshbarger, Akira Hasegawa, Yuki Hasegawa, Takehiro Hashimoto, Meenhard Herlyn, Kelly J Hitchens, Shannan J. Ho Sui, Oliver Hofmann, Ilka Hoof, Fumi Hori, Łukasz Huminiecki, Kei Iida, Tomokatsu Ikawa, Boris R. Janković, Hui Jia, Anagha Joshi, Giuseppe Jurman, Bogumił Kaczkowski, Chieko Kai, Kaoru Kaida, Ai Kaiho, Kazuhiro Kajiyama, Mutsumi Kanamori-Katayama, Artem S. Kasianov, Takeya Kasukawa, Shintaro Katayama, Sachi Kato, Shuji Kawaguchi, Hiroshi Kawamoto, Yuki I. Kawamura, Tsugumi Kawashima, Judith Kempfle, Tony Kenna, Juha Kere, Levon M. Khachigian, Toshio Kitamura, S. Peter Klinken, Alan J. Knox, Miki Kojima, Soichi Kojima, Naoto Kondo, Haruhiko Koseki, Shigeo Koyasu, Sarah Krampitz, Atsutaka Kubosaki, Andrew T. Kwon, Jeroen F. J. Laros, Weon-Ju Lee, Andreas Lennartsson, Kang Li, Berit Lilje, Leonard Lipovich, Alan Mackay‐Sim, Ri‐Ichiroh Manabe, Jessica C. Mar, Benoı̂t Marchand, Anthony Mathelier, Niklas Mejhert, Alison Meynert, Yosuke Mizuno, David Anderson de Lima Morais, Hiromasa Morikawa, Mitsuru Morimoto, Kazuyo Moro, Efthymios Motakis, Hozumi Motohashi, Christine L. Mummery, Mitsuyoshi Murata, Sayaka Nagao-Sato, Yutaka Nakachi, Fumio Nakahara, Toshiyuki Nakamura, Yukio Nakamura, Kenichi Nakazato, Erik van Nimwegen, Noriko Ninomiya, Hiromi Nishiyori, Shohei Noma, Tadasuke Nozaki, Soichi Ogishima, Naganari Ohkura, Hiroko Ohmiya, Hiroshi Ohno, Mitsuhiro Ohshima, Mariko Okada, Yasushi Okazaki, Valerio Orlando, Dmitry A. Ovchinnikov, Arnab Pain, Robert Passier, Margaret Patrikakis, Helena Persson, Silvano Piazza, James Prendergast, Owen J. L. Rackham, Jordan A. Ramilowski, Mamoon Rashid, Timothy Ravasi, Patrizia Rizzu, Marco Roncador, Sugata Roy, Morten Beck Rye, Eri Saijyo, Antti Sajantila, Akiko Saka, Shimon Sakaguchi, Mizuho Sakai, Hiroki Sato, Hironori Satoh, Suzana Savvi, Alka Saxena, Claudio Schneider, Erik Schultes, Gundula Schulze‐Tanzil, Anita Schwegmann, Thierry Sengstag, Guojun Sheng, Hisashi Shimoji, Yishai Shimoni, Jay W. Shin, Christophe Simon, Daisuke Sugiyama, Takaaki Sugiyama, Masanori Suzuki, Rolf Swoboda, Peter A.C. ‘t Hoen, Michihira Tagami, Takahashi Naoko, Jun Takai, Hiroshi Tanaka, Hideki Tatsukawa, Zuotian Tatum, Mark Thompson, Hiroo Toyoda, Tetsuro Toyoda, Eivind Valen, Marc van de Wetering, Linda Berg, Roberto Verardo, Dipti Vijayan, Ilya E. Vorontsov, Wyeth W. Wasserman, Shoko Watanabe, Christine A. Wells, Louise N Winteringham, Ernst J. Wolvetang, Emily J. Wood, Yoko Yamaguchi, Masayuki Yamamoto, Misako Yoneda, Yohei Yonekura, Shigehiro Yoshida, Suzan E. Zabierowski, Peter Zhang, Xiaobei Zhao, S. Zucchelli, Kim Summers, Harukazu Suzuki, Carsten O. Daub, Jun Kawai, Peter Heutink, Yoshihide Hayashizaki, Tom C. Freeman, Boris Lenhard, Vladimir B. Bajić, Martin S. Taylor, Vsevolod J. Makeev, Albin Sandelin, David Hume, Piero Carninci, Yoshihide Hayashizaki,
Naturally occurring regulatory T (Treg) cells, which specifically express the transcription factor forkhead box P3 (Foxp3), are engaged in the maintenance of immunological self-tolerance and homeostasis. By transcriptional start site cluster analysis, we assessed here how genome-wide patterns of DNA methylation or Foxp3 binding sites were associated with Treg-specific gene expression. We found that Treg-specific DNA hypomethylated regions were closely associated with Treg up-regulated transcriptional ...
Tópico(s): T-cell and B-cell Immunology
National Academy of Sciences | Proceedings of the National Academy of Sciences
Mitsutaro Umehara, Yasuhiko Takeda, Tomoyoshi Motohiro, Takenobu Sakai, Hiroki Awano, Ryosuke Maekawa,
We have fabricated Cu2Sn1-xGexS3 thin-film solar cells by cosputtering deposition of Cu and Sn followed by sulfurization in S and GeS2 vapors. The conversion efficiency was significantly improved to be as high as 6.0% compared with the values of Cu2SnS3 solar cells similarly fabricated. Scanning electron microscopy observation revealed that alloying with Ge accelerated the grain growth during the sulfurization process, contributing to the improvement in the conversion efficiency. The bandgap energy ...
Tópico(s): Copper-based nanomaterials and applications
2013 - Institute of Physics | Applied Physics Express
Eiji Yamada, Hidenori Ohkubo, Takuma Higurashi, Eiji Sakai, Hiroki Endo, Hirokazu Takahashi, Eri Uchida, Emi Tanida, Nobuyoshi Izumi, Akira Kanesaki, Yasuo Hata, Tetsuya Matsuura, Nobutaka Fujisawa, Kazuto Komatsu, Shin Maeda, Atsushi Nakajima,
Background/Aims: Left-sided diverticulitis is increasing in Japan, and many studies report that left-sided diverticulitis is more likely to be severe.Therefore, it is important to identify the features and risk factors for left-sided diverticulitis.We hypothesized that left-sided diverticulitis in Japan is related to obesity and conducted a study of the features and risk factors for this disorder in Japan.Methods: Right-sided diverticulitis and left-sided diverticulitis patients (total of 215) were ...
Tópico(s): Appendicitis Diagnosis and Management
2013 - Korean Association for the Study of the Liver | Gut and Liver
Takayuki Sato, Toshio Heike, Haruyuki Fujita, Makoto Iwata, Tomonori Iyoda, Kayo Inaba, Toshiaki Ohteki, Suguru Hasegawa, Kenji Kawada, Yoshiharu Sakai, Hiroki Ikeuchi, Hiroshi Nakase, Akira Niwa, Akifumi Takaori‐Kondo, Norimitsu Kadowaki,
All-trans-retinoic acid (RA) plays a critical role in maintaining immune homeostasis. Mouse intestinal CD103⁺ dendritic cells (DCs) produce a high level of RA by highly expressing retinal dehydrogenase (RALDH)2, an enzyme that converts retinal to RA, and induce gut-homing T cells. However, it has not been identified which subset of human DCs produce a high level of RA. In this study, we show that CD1c⁺ blood myeloid DCs (mDCs) but not CD141(high) mDCs or plasmacytoid DCs exhibited a high level of RALDH2 ...
Tópico(s): T-cell and B-cell Immunology
2013 - American Association of Immunologists | The Journal of Immunology
Yoshinori Inoue, T. Sakai, Hiroki Kumagai,
A combined system of inductively coupled plasma mass spectrometry (ICP-MS) with ion chromatography (IC) was used for the speciation of the chromium (Cr) species. After chelation with ethylenediaminetetraacetic acid (EDTA), Cr(III) and Cr(VI) were separated by anion-exchange chromatography. Subsequently, eluates from a separation column were directly introduced into the ICP-MS and detected at m/z 52 and 53. Separation parameters were optimized for the chromium species. Excelpak ICS-A23 (75 × 4.6 mm I.D.) ...
Tópico(s): Electrochemical Analysis and Applications
1995 - Elsevier BV | Journal of Chromatography A
Hiromichi Mitsuyasu, Naotsugu Hirata, Yasunari Sakai, Hiroki Shibata, Yasuhiko Takeda, Hideaki Ninomiya, Hiroaki Kawasaki, N. Tashiro, Y Fukumaki,
The human dopamine D4 receptor (DRD4) is of major interest in molecular studies of schizophrenia and personality traits. We examined the association of schizophrenia and polymorphisms in the upstream region of the DRD4 gene (−768G>A in the negative modulator region; −521C>T, −376C>T, and −291C>T in the cell type-specific promoter region; and −616C>G between the two regions) in 208 schizophrenic patients and 210 normal controls. No significant difference in genotype and allele frequencies was observed between ...
Tópico(s): Neurotransmitter Receptor Influence on Behavior
2001 - Springer Nature | Journal of Human Genetics