Akira Hara, Makoto Nakagawa, Hiroyuki Taniguchi, Hideo Sawada,
... author on: Oxford Academic PubMed Google Scholar Hiroyuki Taniguchi, Hiroyuki Taniguchi Department of Biochemistry, Gifu Pharmaceutical UniversityMitahora-higashi, Gifu, ...
Tópico(s): Pharmacogenetics and Drug Metabolism
1989 - Oxford University Press | The Journal of Biochemistry
Hitoshi Taniguchi, Hiroyuki Hatano, Hideo Hasegawa, Tetsuo Maruyama,
... radical with amino acid derivatives and related compoundsHitoshi Taniguchi, Hiroyuki Hatano, Hideo Hasegawa, and Tetsuo MaruyamaCite this: J. ...
Tópico(s): Radical Photochemical Reactions
1970 - American Chemical Society | The Journal of Physical Chemistry
Midori Shimada, Hirokazu Taniguchi, Hiroyuki Yamaguchi, Hiroshi Gyotoku, Daisuke Sasaki, Norihito Kaku, Chikako Senju, Hiroaki Senju, Erika Imamura, Shinnosuke Takemoto, Kazuko Yamamoto, Noriho Sakamoto, Yasushi Obase, Tomoshi Tsuchiya, Minoru Fukuda, Hiroshi Soda, Kazuto Ashizawa, Junya Fukuoka, Takeshi Nagayasu, Katsunori Yanagihara, Hiroshi Mukae,
Midori Shimada, Hirokazu Taniguchi, Hiroyuki Yamaguchi, Hiroshi Gyotoku, Daisuke Sasaki, Norihito Kaku, Chikako Senju, Hiroaki Senju, Erika Imamura, Shinnosuke Takemoto, Kazuko Yamamoto, Noriho Sakamoto, ...
Tópico(s): Neuroblastoma Research and Treatments
2023 - AME Publishing Company | Translational Lung Cancer Research
Takashi Higuchi, Norio Yamamoto, Hideji Nishida, Katsuhiro Hayashi, Akihiko Takeuchi, Hiroaki Kimura, Shinji Miwa, Hiroyuki Inatani, Shingo Shimozaki, Takashi Kato, Yu Aoki, Kensaku Abe, Yuta Taniguchi, Hiroyuki Tsuchiya,
To preserve the joint structure in order to maintain good limb function in patients with osteosarcoma, we perform epiphyseal or metaphyseal osteotomy and reconstruction using frozen autografts that contain a tumour treated with liquid nitrogen. There are two methods of using liquid nitrogen-treated autografts: the free-freezing method and the pedicle-freezing method. The purpose of this study was to evaluate the results of intentional joint-preserving reconstruction using the free-freezing method ...
Tópico(s): Bone Tumor Diagnosis and Treatments
2017 - Springer Science+Business Media | International Orthopaedics
Satoshi Ito, Keishi Akaiwa, Yusuke Funabashi, Hiroki Nishikawa, Xiangbo Kong, Ittetsu Taniguchi, Hiroyuki Tomiyama,
Delivery drones have been attracting attention as one of the promising technologies to deliver packages. Several research studies on routing problems specifically for drone delivery scenarios have extended Vehicle Routing Problems (VRPs). Most existing VRPs are based on Traveling Salesman Problems (TSPs) for minimizing the overall distance. On the other hand, VRPs for drone delivery have been aware of energy consumption due to the consideration of battery capacity. Despite hovering motions with loading ...
Tópico(s): Robotic Path Planning Algorithms
2022 - Multidisciplinary Digital Publishing Institute | Drones
Keigo Chida, Akihito Kawazoe, Masahito Kawazu, Toshihiro Suzuki, Yoshiaki Nakamura, Tetsuya Nakatsura, Takeshi Kuwata, Toshihide Ueno, Yasutoshi Kuboki, Daisuke Kotani, Takashi Kojima, Hiroya Taniguchi, Hiroyuki Mano, Masafumi Ikeda, Kohei Shitara, Itaru Endo, Takayuki Yoshino,
This study performed a comprehensive molecular characterization of microsatellite instability-high (MSI-H)/mismatch repair-deficient (dMMR) gastrointestinal (GI) tumors to elucidate predictors of response to PD-1 blockade.Forty-five patients with MSI-H/dMMR GI tumors, including gastric cancer, colorectal cancer, cholangiocarcinoma, small intestine cancer, pancreatic cancer, and duodenal cancer, receiving PD-1 blockade were analyzed. We conducted the genomic profiling of GI tumors by whole-exome sequencing ...
Tópico(s): Gastric Cancer Management and Outcomes
2021 - American Association for Cancer Research | Clinical Cancer Research
Michio Inoue, S. Noguchi, Kyuto Sonehara, Keiko Nakamura‐Shindo, Akira Taniguchi, Hiroyuki Kajikawa, Hisayoshi Nakamura, Keiko Ishikawa, Megumu Ogawa, Shinichiro Hayashi, Yukinori Okada, Satoshi Kuru, Aritoshi Iida, Ichizo Nishino,
Tópico(s): Nuclear Structure and Function
2021 - Springer Science+Business Media | Acta Neuropathologica
Shinji Miwa, Toshiharu Shirai, Norio Yamamoto, Katsuhiro Hayashi, Akihiko Takeuchi, Kaoru Tada, Yoshitomo Kajino, Takashi Higuchi, Kensaku Abe, Hisaki Aiba, Yuta Taniguchi, Hiroyuki Tsuchiya,
Use of an implant is one of the risk factors for surgical site infection (SSI) after malignant bone tumor resection. We developed a new technique of coating titanium implant surfaces with iodine to prevent infection. In this retrospective study, we investigated the risk factors for SSI after malignant bone tumor resection and to evaluate the efficacy of iodine-coated implants for preventing SSI.Data from 302 patients with malignant bone tumors who underwent malignant bone tumor resection and reconstruction ...
Tópico(s): Sarcoma Diagnosis and Treatment
2019 - BioMed Central | BMC Cancer
Akihiko Takeuchi, Norio Yamamoto, Katsuhiro Hayashi, Hidenori Matsubara, Hiroaki Kimura, Shinji Miwa, Takashi Higuchi, Kensaku Abe, Yuta Taniguchi, Hiroyuki Tsuchiya,
Epiphyseal-preservation surgery for osteosarcoma is an alternative method which has been indicated carefully to selected patients. The tumor-devitalised autograft treated with liquid nitrogen procedure is one of the biological reconstruction method to reconstruct the defect after tumor excision. The limb length discrepancy is usually appeared in children with their growth after limb-sparing surgery. This study was aimed to investigated the growth of residual epiphysis following epiphyseal-preservation ...
Tópico(s): Musculoskeletal synovial abnormalities and treatments
2018 - BioMed Central | BMC Musculoskeletal Disorders
Mamer S. Rosario, Katsuhiro Hayashi, Norio Yamamoto, Akihiko Takeuchi, Shinji Miwa, Yuta Taniguchi, Hiroyuki Tsuchiya,
Reports showing high recurrence rates for intralesional curettage and bone grafting have made the current treatment principle for fibrous dysplasia controversial. This study aimed to report the postoperative clinical outcomes from three minimally invasive surgical strategies we use for monostotic fibrous dysplasia (MFD).Twelve patients with MFD presenting with no pathologic fracture or deformity and treated with one of three surgical strategies-plain open biopsy, plain alpha-tricalcium phosphate ( ...
Tópico(s): Oral and Maxillofacial Pathology
2017 - BioMed Central | World Journal of Surgical Oncology
Kotomi Taniguchi, Hiroyuki Ozeki, Masao Saito,
Abstract We observed the <?CDATA $J=5-4$?> rotational lines of the normal species and three 13 C isotopologues of HC 3 N at the 45 GHz band toward two low-mass starless cores, L1521B and L134N (L183), using the Nobeyama 45 m radio telescope in order to study the main formation pathways of HC 3 N in each core. The abundance ratios of the three 13 C isotopologues in L1521B are derived to be [H 13 CCCN]:[HC 13 CCN]:[HCC 13 CN] = 0.98 (±0.14):1.00:1.52 (±0.16) ( <?CDATA $1\sigma $?> ). The fractionation pattern is consistent ...
Tópico(s): Atmospheric Ozone and Climate
2017 - IOP Publishing | The Astrophysical Journal
Gotaro Kojima, Steve Iliffe, Yu Taniguchi, Hiroyuki Shimada, Hiromi Rakugi, Kate Walters,
Japan's population is aging more rapidly than that of any other country. Frailty has recently been recognized as an important priority. Understanding the basic epidemiology of frailty in Japan, which is an example of a rapidly aging society, will be beneficial for Japan as well as other countries expecting an aging population. A systematic literature search of 11 electronic databases was conducted in March 2016 using a comprehensive set of Medical Subject Heading and text terms for any studies published ...
Tópico(s): Health Systems, Economic Evaluations, Quality of Life
2016 - Japan Epidemiological Association | Journal of Epidemiology
Masahiro Sugiyama, Shinichiro Asayama, Takanobu Kosugi, Atsushi Ishii, Seita Emori, Jiro Adachi, Keigo Akimoto, Masatomo Fujiwara, Tomoko Hasegawa, Yasushi Hibi, Kimiko Hirata, Toru Ishii, Takeshi Kaburagi, Yuki Kita, Shigeki Kobayashi, Atsushi Kurosawa, Manabu Kuwata, Kooiti Masuda, Makoto Mitsui, Taku Miyata, Hiroshi Mizutani, Sumie Nakayama, Kazuyo Oyamada, Takaaki Sashida, Miho Sekiguchi, Kiyoshi Takahashi, Yukari Takamura, Taki Junichi, Taketoshi Taniguchi, Hiroyuki Tezuka, Takahiro Ueno, Shingo Watanabe, Rie Watanabe, Naoyuki Yamagishi, Go Yoshizawa,
Tópico(s): Climate Change and Health Impacts
2016 - Springer Science+Business Media | Sustainability Science
Atsunobu Masuno, Norimasa Nishiyama, Fumio Sato, Naoyuki Kitamura, Takashi Taniguchi, Hiroyuki Inoue,
Silica glasses permanently densified at high temperatures show unexpected increase of both the refractive index and the Abbe number. Glasses densified at a higher temperature underwent homogeneous evolution of their intermediate structural ordering.
Tópico(s): Silicon Nanostructures and Photoluminescence
2016 - Royal Society of Chemistry | RSC Advances
Kotomi Taniguchi, Hiroyuki Ozeki, Masao Saito, Nami Sakai, Fumitaka Nakamura, Seiji Kameno, Shuro Takano, Satoshi Yamamoto,
We observed the J = 9-8 and 16-15 rotational transitions of the normal species and five 13C isotopologues of HC5N to study its formation mechanisms toward the cyanopolyyne peak in Taurus Molecular Cloud-1, with the 45-m radio telescope of Nobeyama Radio Observatory. We detected the five 13C isotopologues with high signal-to-noise ratios between 12 and 20, as well as the normal species. The abundance ratios of the five 13C isotopologues of HC5N are found to be 1.00:0.97:1.03:1.05:1.16 (0.19) for [H13CCCCCN]:[ ...
Tópico(s): Atmospheric Ozone and Climate
2016 - IOP Publishing | The Astrophysical Journal
Takaaki Taniguchi, Hiroyuki Yokoi, Masaki Nagamine, Hikaru Tateishi, Asami Funatsu, Kazuto Hatakeyama, Chikako Ogata, Masao Ichida, Hiroaki Ando, Michio Koinuma, Yasumichi Matsumoto,
Optical and magnetic properties of graphene oxide (GO) have been intensively investigated because of the promising applications of GO-related materials in various technical fields. So far, the optical and magnetic properties of GO have been discussed independently. However, localized electronic states in reduced GO may simultaneously add optical transitions and spin moments in sp2 nanodomains in GO nanosheets. In the present study, the structural, optical, and magnetic properties of graphene oxide ( ...
Tópico(s): Carbon and Quantum Dots Applications
2014 - American Chemical Society | The Journal of Physical Chemistry C
Yuma Fukutomi, Masami Taniguchi, Hiroyuki Nakamura, Kohki Akiyama,
Abstract Background Recent studies have highlighted the importance of extra‐intestinal routes of sensitization to food‐related allergens as the cause of epidemics of food allergy. Instances of Japanese women developing food allergy to wheat after exposure to hydrolyzed wheat protein ( HWP ) present in facial soap have been reported. However, the epidemiologic impact of these ingredients as a cause of food allergy has not been well studied. Methods To clarify the epidemiological relationship between ...
Tópico(s): Allergic Rhinitis and Sensitization
2014 - Wiley | Allergy
Hisaaki Zaimoku, H Nishide, Asami Nishibata, Naoya Goto, Tsuyoshi Taniguchi, Hiroyuki Ishibashi,
The first total syntheses of (±)-serratine, (±)-lycoposerramine T, and (±)-lycopoclavamine B have been accomplished. The functionalized octahydroindane skeleton of these natural products was constructed by an efficient Diels–Alder reaction of an α-alkynylcyclopentenone and the stereoselective introduction of a tertiary hydroxyl group. Two of these natural products were divergently synthesized from the same synthetic intermediate at a later stage.
Tópico(s): Phytochemical compounds biological activities
2013 - American Chemical Society | Organic Letters
Daisuke Hirose, Tsuyoshi Taniguchi, Hiroyuki Ishibashi,
Aerobic recycling: A catalytic amount of a hydrazine reagent is sufficient to promote Mitsunobu reactions in the presence of triphenylphosphine, an iron catalyst, and air. The active form of the catalyst, an azo species, can be readily generated by iron-catalyzed aerobic oxidation. MS=molecular sieves, Pc=phthalocyanine. As a service to our authors and readers, this journal provides supporting information supplied by the authors. Such materials are peer reviewed and may be re-organized for online ...
Tópico(s): Metal-Catalyzed Oxygenation Mechanisms
2013 - Wiley | Angewandte Chemie International Edition
Daisuke Hirose, Tsuyoshi Taniguchi, Hiroyuki Ishibashi,
Aerobes Recycling: Eine katalytische Menge eines Hydrazinreagens genügt, um Mitsunobu-Reaktionen in Gegenwart von Triphenylphosphan, einem Eisen-Katalysator und Luft zu vermitteln. Die aktive Form des Katalysators, eine Azo-Spezies, kann einfach durch Eisen-katalysierte aerobe Oxidation erzeugt werden. MS=Molekularsieb, Pc=Phthalocyanin.
Tópico(s): Metal-Catalyzed Oxygenation Mechanisms
2013 - Wiley | Angewandte Chemie
Hisaaki Zaimoku, Takashi Hatta, Tsuyoshi Taniguchi, Hiroyuki Ishibashi,
A new method for direct α-functionalization of 2,3-disubstituted indoles has been developed. The present reaction provides α-acetoxy indole derivatives regioselectively under mild conditions using commercially available and nontoxic iodine reagents. This reaction is a useful synthetic tool because obtained α-acetoxy products can be transformed into various functionalized indoles by substitution reactions with nucleophiles.
Tópico(s): Synthesis and Catalytic Reactions
2012 - American Chemical Society | Organic Letters
Fumiya Taniguchi, Hiroyuki Fukuoka, J. Tanaka,
Tea is one of the most popular beverages in the world and the tea plant, Camellia sinensis (L.) O. Kuntze, is an important crop in many countries. To increase the amount of genomic information available for C. sinensis, we constructed seven cDNA libraries from various organs and used these to generate expressed sequence tags (ESTs). A total of 17,458 ESTs were generated and assembled into 5,262 unigenes. About 50% of the unigenes were assigned annotations by Gene Ontology. Some were homologous to ...
Tópico(s): Plant and Fungal Interactions Research
2012 - Japanese Society of Breeding | Breeding Science
Hisaaki Zaimoku, Tsuyoshi Taniguchi, Hiroyuki Ishibashi,
A synthetic study of actinophyllic acid based on an original strategy has been described. A transannular acyl radical cyclization allowed us to obtain a key bicyclo[3.3.2] framework, and construction of a core of the target alkaloid has been accomplished by subsequent introduction of a C2 unit.
Tópico(s): Alkaloids: synthesis and pharmacology
2012 - American Chemical Society | Organic Letters
Hisaji Taniguchi, Hiroyuki Hashimoto, Asao Hosoda, Takashi Kometani, Takuo Tsuno, Shuji Adachi,
Consuming rice as the staple, 0.95 million tons of rice bran is produced annually in Japan as a by-product from the rice milling process. Bran is used in several applications such as animal feed and fertilizer for mushroom cultivation, but most of it has been discarded as an agricultural waste although it contains various functional substances, such as γ-oryzanol, ferulic acid, sterol, wax, ceramide, phytin, inositol and protein. It could be considered a scarcely used but promising resource. As ...
Tópico(s): Fermentation and Sensory Analysis
2012 - Japanese Society for Food Science and Technology | Nippon Shokuhin Kagaku Kogaku Kaishi
Takeshi Taniguchi, Hiroyuki Usuki, Jun-Ichi Kikuchi, Muneto Hirobe, Naoko Miki, Kenji Fukuda, Guosheng Zhang, Linhe Wang, Ken Yoshikawa, Norikazu Yamanaka,
Tópico(s): Biocrusts and Microbial Ecology
2011 - Springer Science+Business Media | Mycorrhiza
Agustín F. Fernández, Yassen Assenov, José I. Martín‐Subero, Balázs Bálint, Reiner Siebert, Hiroaki Taniguchi, Hiroyuki Yamamoto, Manuel Hidalgo, Aik Choon Tan, Oliver Galm, Isidró Ferrer, Montse Sánchez‐Céspedes, Alberto Villanueva, F. Javier Carmona, José V. Sánchez‐Mut, María Berdasco, Vı́ctor Moreno, Gabriel Capellà, David Monk, Esteban Ballestar, Santiago Ropero, Ramón Martínez, Marta Sänchez‐Carbayo, Felipe Prósper, Xabier Agirre, Mario F. Fraga, Osvaldo Graña‐Castro, Luis A. Pérez‐Jurado, Jaume Mora, Susana Puig, Jaime Prat, Lina Badimón, Annibale Alessandro Puca, Stephen J. Meltzer, Thomas Lengauer, John Bridgewater, Christoph Bock, Manel Esteller,
Most of the studies characterizing DNA methylation patterns have been restricted to particular genomic loci in a limited number of human samples and pathological conditions. Herein, we present a compromise between an extremely comprehensive study of a human sample population with an intermediate level of resolution of CpGs at the genomic level. We obtained a DNA methylation fingerprint of 1628 human samples in which we interrogated 1505 CpG sites. The DNA methylation patterns revealed show this ...
Tópico(s): Cancer-related gene regulation
2011 - Cold Spring Harbor Laboratory Press | Genome Research
Yuma Fukutomi, Masami Taniguchi, Hiroyuki Nakamura, Satoshi Konno, Masaharu Nishimura, Yukio Kawagishi, Chiharu Okada, Yasushi Tanimoto, Kiyoshi Takahashi, Akira Akasawa, Kazuo Akiyama,
Increasing amounts of data have shown that some Asian populations are more susceptible to increased weight and development of noncommunicable disease than Western populations. However, little is known about the association between increased weight, particularly within the normal range, and the development of asthma among Asian populations.To examine the association between increased body mass index (BMI) and asthma among Japanese adults, data from a nationwide population-based cross-sectional survey ...
Tópico(s): Obesity, Physical Activity, Diet
2011 - Karger Publishers | International Archives of Allergy and Immunology
Tetsuji Aoyagi, Nobuko Yamamoto, Mochammad Hatta, D. Tanno, Akiko Miyazato, Keiko Ishii, Kazuo Suzuki, Toshinori Nakayama, M. Taniguchi, Hiroyuki Kunishima, Yoichi Hirakata, M. Kaku, Kazuyoshi Kawakami,
Invariant NK T (iNKT) cells are known to play a critical role in the regulation of inflammatory responses in various clinical settings. In the present study, we assessed the contribution of iNKT cells to the development of acute lung injury (ALI), which was caused by intra-tracheal administration of LPS. Jα18 gene-disrupted mice lacking these cells underwent neutrophilic inflammatory responses in lungs at an equivalent level as control mice. Next, mice were sensitized intra-tracheally with α-galactosylceramide, ...
Tópico(s): Pediatric health and respiratory diseases
2010 - Oxford University Press | International Immunology
Hiroya Tamaki, Yoshiro Naito, Masaaki Lee‐Kawabata, Yuki Taniguchi, Hiroyuki Hao, Seiichi Hirota, Seiki Hasegawa, Tohru Masuyama, Hiroyasu Ogawa,
Tópico(s): Coagulation, Bradykinin, Polyphosphates, and Angioedema
2010 - Springer Science+Business Media | International Journal of Hematology
Kazumasa Muramoto, Kazuhiro Ohta, Kyoko Shinzawa‐Itoh, K. Kanda, Maki Taniguchi, Hiroyuki Nabekura, Eiki Yamashita, Tomitake Tsukihara, Shinya Yoshikawa,
The O 2 reduction site of cytochrome c oxidase (CcO), comprising iron (Fe a 3 ) and copper (Cu B ) ions, is probed by x-ray structural analyses of CO, NO, and CN - derivatives to investigate the mechanism of the complete reduction of O 2 . Formation of the derivative contributes to the trigonal planar coordination of and displaces one of its three coordinated imidazole groups while a water molecule becomes hydrogen bonded to both the CN - ligand and the hydroxyl group of Tyr244. When O 2 is bound to , it is negatively ...
Tópico(s): Electrochemical Analysis and Applications
2010 - National Academy of Sciences | Proceedings of the National Academy of Sciences