Keita Gooh, Minako Ueda, Kana Aruga, Jong-Ho Park, Hideyuki Arata, Tetsuya Higashiyama, Daisuke Kurihara,
Intercellular communications are essential for cell proliferation and differentiation during plant embryogenesis. However, analysis of intercellular communications in living material in real time is difficult owing to the restricted accessibility of the embryo within the flower. We established a live-embryo imaging system to visualize cell division and cell fate specification in Arabidopsis thaliana from zygote division in real time. We generated a cell-division lineage tree for early embryogenesis ...
Tópico(s): Plant tissue culture and regeneration
2015 - Elsevier BV | Developmental Cell
Seok Jin Kim, Dok Hyun Yoon, Hye Jin Kang, Jung Yong Hong, Ho Sup Lee, Sung Yong Oh, Ho‐Jin Shin, Jee Hyun Kong, Jun Ho Yi, Kana Sakamoto, Young Hyeh Ko, Jooryung Huh, Seung‐Sook Lee, Kengo Takeuchi, Dong‐Yeop Shin, Cheolwon Suh, Won Seog Kim,
Abstract Background The upregulated expression of the JAK/STAT pathway promotes tumor growth in Hodgkin lymphoma (HL) and primary mediastinal large B-cell lymphoma (PMBCL). Based on the hypothesis that JAK2 is a therapeutic target, we performed a prospective pilot study using ruxolitinib. Methods Relapsed or refractory patients with HL or PMBCL were eligible for this study, and JAK2 amplification was assessed by fluorescence in situ hybridization. Ruxolitinib was administered orally at a dose of 20 ...
Tópico(s): Viral-associated cancers and disorders
2019 - BioMed Central | BMC Cancer
Sven Hennig, Geraldine Kong, Taro Mannen, Agata Sadowska, Simon Kobelke, Amanda Blythe, Gavin J. Knott, K. Swaminathan Iyer, Diwei Ho, Estella A. Newcombe, Kana Hosoki, Naoki Goshima, Tetsuya Kawaguchi, Danny M. Hatters, Laura Trinkle‐Mulcahy, Tetsuro Hirose, Charles S. Bond, Archa H. Fox,
Prion-like domains (PLDs) are low complexity sequences found in RNA binding proteins associated with the neurodegenerative disorder amyotrophic lateral sclerosis. Recently, PLDs have been implicated in mediating gene regulation via liquid-phase transitions that drive ribonucleoprotein granule assembly. In this paper, we report many PLDs in proteins associated with paraspeckles, subnuclear bodies that form around long noncoding RNA. We mapped the interactome network of paraspeckle proteins, finding ...
Tópico(s): Prion Diseases and Protein Misfolding
2015 - Rockefeller University Press | The Journal of Cell Biology
Atsushi Kobayashi, Daisuke Yamamoto, Hiroyuki Horiki, Kana Sawaguchi, Takeshi Matsumoto, Kiyohiko Nakajima, Ho‐Chol Chang, Masako Kato,
Photoreactivities of Ni(II)- and Pt(II)-hydrazone complexes, [NiCl(L)] (Ni1) and [PtCl(L)] (Pt1), respectively [HL = 2-(diphenylphosphino)benzaldehyde-2-pyridylhydrazone], were investigated in detail via UV-vis absorption, (1)H nuclear magnetic resonance (NMR) spectroscopy, and electrospray ionization time-of-flight (ESI-TOF) mass spectrometry; the two photoproducts obtained from the photoreaction of Pt1 were also successfully identified via X-ray analysis. The absorption bands of the Ni1 and Pt1 complexes ...
Tópico(s): Metal complexes synthesis and properties
2014 - American Chemical Society | Inorganic Chemistry
Akane Takemura, Kana Hashimoto, Alex Ho, Michele Bessinger, Sandra Law, Robert E. Schifferle, Sebastian G. Ciancio,
To evaluate the efficacy of a new oral rinse containing sodium hyaluronate and other functional ingredients in reducing xerostomia-associated symptoms.In this 8-week, double-blind crossover study, xerostomia subjects used all three of GUM®HYDRAL™ Oral Rinse, placebo rinse, and Biotene® Oral Rinse as active control. Visual Analog Scale, a dry mouth questionnaire, Oral Health Impact Profile-14, unstimulated saliva flow rate (USFR), and Revised Oral Assessment Guide (ROAG) were assessed before and after ...
Tópico(s): Oral Health Pathology and Treatment
2022 - Wiley | Oral Diseases
Martin Ho Kwan Ip, Kana Imuta, Virginia Slaughter,
Correct counting respects the stable order principle whereby the count terms are recited in a fixed order every time. The 4 experiments reported here tested whether precounting infants recognize and prefer correct stable-ordered counting. The authors introduced a novel preference paradigm in which infants could freely press two buttons to activate videos of counting events. In the "correct" counting video, number words were always recited in the canonical order ("1, 2, 3, 4, 5, 6"). The "incorrect" ...
Tópico(s): Reading and Literacy Development
2018 - American Psychological Association | Developmental Psychology
Xiaoting Ye, Kana Morikawa, Shih‐Hsin Ho, Michihiro Araki, Keiji Nishida, Tomohisa Hasunuma, Kiyotaka Y. Hara, Akihiko Kondo,
Measurement of mitochondrial ATP synthesis is a critical way to compare cellular energetic performance. However, fractionation of mitochondria requires large amounts of cells, lengthy purification procedures, and an extreme caution to avoid damaging intact mitochondria, making it the highest barrier to high-throughput studies of mitochondrial function. To evaluate 45 genes involved in oxidative phosphorylation in Saccharomyces cerevisiae, we aimed to develop a simple and rapid method to measure ...
Tópico(s): Photosynthetic Processes and Mechanisms
2015 - BioMed Central | Microbial Cell Factories
Andrew J. Laster, TJ Palker, EA Harden, W Ho, Kana Naito, B DuPont, BF Haynes,
Abstract Antibody 3–40 defines a 35- to 40-kd surface antigen present on T lymphoblastic leukemia (T-ALL) cells that is absent on normal hematopoietic cells (Naito et al, Blood 62:852, 1983). Using immunoblot analysis of cytoskeletal proteins and indirect immunofluorescence of cell lines treated with various cytoskeletal inhibitors, in this report we have demonstrated that antibody 3–40 also identifies vimentin intermediate filaments (IMF) within the HSB-2 (T-ALL) cell line as well as in normal thymocytes, ...
Tópico(s): Cutaneous lymphoproliferative disorders research
1985 - Elsevier BV | Blood
Elke Dworatzek, Shokoufeh Mahmoodzadeh, Cindy Schriever, Kana Kusumoto, Lisa Krämer, Gabriela Leão Santos, Daniela Fliegner, Yuet‐Kin Leung, Shuk‐Mei Ho, Wolfram‐Hubertus Zimmermann, Susanne Lutz, Vera Regitz‐Zagrosek,
Abstract Aims Sex differences in cardiac fibrosis point to the regulatory role of 17β-Estradiol (E2) in cardiac fibroblasts (CF). We, therefore, asked whether male and female CF in rodent and human models are differentially susceptible to E2, and whether this is related to sex-specific activation of estrogen receptor alpha (ERα) and beta (ERβ). Methods and results In female rat CF (rCF), 24 h E2-treatment (10−8 M) led to a significant down-regulation of collagen I and III expression, whereas both collagens ...
Tópico(s): Protease and Inhibitor Mechanisms
2018 - Oxford University Press | Cardiovascular Research
Hiroshi Orihara, Kana Tanabu, Yang Ho Na,
We have investigated the scaling properties of immiscible fluid blends in shear flow and electric fields. Scaling relations were derived by dimensional analysis. For example, when they are subjected to a step electric field at a constant shear rate, transient apparent viscosity depends only on strain, as long as \(\dot{\gamma}/E^{2}\) is constant, where \(\dot{\gamma}\) and E are, respectively, the shear rate and electric field. Another scaling property was derived for the characteristic length of the ...
Tópico(s): Theoretical and Computational Physics
2008 - Physical Society of Japan | Journal of the Physical Society of Japan
Jun Wang, Georgia E. Hodes, Hongxing Zhang, Song Zhang, Wei Zhao, Sam A. Golden, Weina Bi, Caroline Ménard, Veronika Kana, Marylène Leboeuf, Marc Xie, Dana Bregman, Madeline L. Pfau, Meghan E. Flanigan, Adelaida Esteban‐Fernández, Shrishailam Yemul, Ali Sharma, Lap Ho, Richard A. Dixon, Miriam Mérad, Ming‐Hu Han, Scott J. Russo, Giulio Maria Pasinetti,
Abstract Major depressive disorder is associated with abnormalities in the brain and the immune system. Chronic stress in animals showed that epigenetic and inflammatory mechanisms play important roles in mediating resilience and susceptibility to depression. Here, through a high-throughput screening, we identify two phytochemicals, dihydrocaffeic acid (DHCA) and malvidin-3′- O -glucoside (Mal-gluc) that are effective in promoting resilience against stress by modulating brain synaptic plasticity and ...
Tópico(s): Neuroinflammation and Neurodegeneration Mechanisms
2018 - Nature Portfolio | Nature Communications
Julia Rieke Hagemann, Frank Lamy, Helge W. Arz, Lester Lembke‐Jene, Alexandra Auderset, Naomi Harada, Sze Ling Ho, Shinya Iwasaki, Jérôme Kaiser, Carina B. Lange, Masafumi Murayama, Kana Nagashima, Norbert R Nowaczyk, Alfredo Martínez‐García, Ralf Tiedemann,
Terrestrial glacial records from the Patagonian Andes and New Zealand Alps document quasi-synchronous Southern Hemisphere–wide glacier advances during the late Quaternary. However, these records are inherently incomplete. Here, we provide a continuous marine record of western–central Patagonian ice sheet (PIS) extent over a complete glacial–interglacial cycle back into the penultimate glacial (~140 ka). Sediment core MR16-09 PC03, located at 46°S and ~150 km offshore Chile, received high terrestrial ...
Tópico(s): Methane Hydrates and Related Phenomena
2024 - National Academy of Sciences | Proceedings of the National Academy of Sciences
Bum-Ho Bin, Jinhyuk Bhin, Mikiro Takaishi, Koh‐éi Toyoshima, Saeko Kawamata, Kana Ito, Takafumi Hara, Takashi Watanabe, Tarou Irié, Teruhisa Takagishi, Su-Hyon Lee, Haeng-Sun Jung, Sangchul Rho, Juyeon Seo, Dong‐Hwa Choi, Daehee Hwang, Haruhiko Koseki, Osamu Ohara, Shigetoshi Sano, Takashi Tsuji, Kenji Mishima, Toshiyuki Fukada,
Significance Although the epidermis of the skin is the first tissue to manifest a zinc deficiency, the mechanisms underlying zinc-mediated epidermal formation are largely unknown. We demonstrated that the zinc transporter ZIP10, which is highly expressed in the outer root shelf of hair follicles, is essential for epidermal formation. Ablating Zip10 caused epidermal hypoplasia by down-regulating the transcriptional activity of p63, whereas ZIP10-mediated zinc influx promoted p63 transactivation to ...
Tópico(s): Skin and Cellular Biology Research
2017 - National Academy of Sciences | Proceedings of the National Academy of Sciences
Seok Jin Kim, Hye Jin Kang, Shin Dong-Yeop, Ho Sup Lee, Sung Yong Oh, Ho‐Jin Shin, Dok Hyun Yoon, Jung Yong Hong, Jee Hyun Kong, Kana Sakamoto, Young Hyeh Ko, Kengo Takeuchi, Cheolwon Suh, Won Seog Kim,
Abstract Background JAK2 expression and activity increased in classical Hodgkin lymphoma (HL) and primary mediastinal large B-cell lymphoma (PMBCL) because both of them were reported to have chromosome 9p24.1/JAK2 amplification. Thus, JAK2 has been suggested as a potential therapeutic target in both disease having similar clinical and genetic features, and a previous in vitro and in vivo study showed cHL and PMBCL with JAK2 amplification were sensitive to JAK2 inhibition. However, the efficacy of ...
Tópico(s): Chronic Lymphocytic Leukemia Research
2016 - Elsevier BV | Blood
Tina S. Alster, Steven R. Kohn,
... Ann Plast Surg 1987; 18: 47–50. 140 Kana, JS, Hutschenreiter, G, Haina, D, et al. Effects of low-power density laser radiation on healing of open skin wounds in rats. Arch Surg 1981; 116: 293–296. 141 Basford, JR, Hallman, HO, Sheffield, CG, et al. Comparison of cold-quartz ...
Tópico(s): Nail Diseases and Treatments
1992 - Wiley | International Journal of Dermatology
Kana Orihashi, Akio Yamauchi, Saiya Fujiwara, Mizue Asada, Toshikazu Nakamura, Joseph Ka‐Ho Hui, Nobuo Kimizuka, Kenichiro Tateishi, Т. Уесака, Nobuhiro Yanai,
The generation of spin polarization is key in quantum information science and dynamic nuclear polarization. Polarized electron spins with long spin–lattice relaxation times (T1) at room temperature are important for these applications but have been difficult to achieve. We report the realization of spin-polarized radicals with extremely long T1 at room temperature in a metal–organic framework (MOF) in which azaacene chromophores are densely integrated. Persistent radicals are generated in the MOF ...
Tópico(s): Organic and Molecular Conductors Research
2023 - American Chemical Society | Journal of the American Chemical Society
... issue with her gender expression, her older sister, Kana, is frustrated that Ho'onani won't act more like a girl. ...
Tópico(s): Research in Social Sciences
2019 - Johns Hopkins University Press | Bulletin of the Center for Children's Books./Bulletin of the Center for Children's Books
Tamami Fujiki, Fumiaki Ando, Kana Murakami, Kiyoshi Isobe, Takayasu Mori, Koichiro Susa, Naohiro Nomura, Eisei Sohara, Tatemitsu Rai, Shinichi Uchida,
Abstract Tolvaptan, a vasopressin type 2 receptor antagonist initially developed to increase free-water diuresis, has been approved for the treatment of autosomal dominant polycystic kidney disease in multiple countries. Furthermore, tolvaptan has been shown to improve the renal functions in rodent models of chronic kidney disease (CKD); however, the underlying molecular mechanisms remain unknown. CKD is characterized by increased levels of oxidative stress, and an antioxidant transcription factor— ...
Tópico(s): Dialysis and Renal Disease Management
2019 - Nature Portfolio | Scientific Reports
Tomoaki Terasako, Kana Hashimoto, Y Nomoto, Sho Shirakata, Shigehiro Isomura, Eiki Niwa, K. Masumoto,
Doping of Ho into AgGaS2 has been carried out by the thermal diffusion of Ho element into the undoped crystal. Sharp photoluminescence (PL) lines related to the 5S2→5I8 and 5F3→5I7 transitions in the Ho3+ ion are observed in the energy regions 2.23–2.28 and 1.85–1.93 eV, respectively. Temperature dependence and excitation wavelength dependence of the PL indicate the existence of at least four types of Ho-related luminescence centers. Moreover, it is found that PL lines from different Ho-related luminescence ...
Tópico(s): Luminescence Properties of Advanced Materials
2000 - Elsevier BV | Journal of Luminescence
Raymond Y. Kwong, Yin Ge, Kevin Steel, Scott E. Bingham, Shuaib Abdullah, Kana Fujikura, Wei Wang, Ankur Pandya, Yi-Yun Chen, J. Ronald Mikolich, Sebastian Boland, Andrew E. Arai, W. Patricia Bandettini, Sujata M. Shanbhag, Amit R. Patel, Akhil Narang, Afshin Farzaneh‐Far, Benjamin Romer, John F. Heitner, Jean Ho, Jaspal Singh, Chetan Shenoy, Andrew Hughes, Steve Leung, Meera Marji, Jorge A. González, Sandeep Mehta, Dipan J. Shah, Dany Debs, Subha V. Raman, Avirup Guha, Victor A. Ferrari, Jeanette Schulz‐Menger, Rory Hachamovitch, Matthias Stuber, Orlando P. Simonetti,
Stress cardiac magnetic resonance imaging (CMR) has demonstrated excellent diagnostic and prognostic value in single-center studies.This study sought to investigate the prognostic value of stress CMR and downstream costs from subsequent cardiac testing in a retrospective multicenter study in the United States.In this retrospective study, consecutive patients from 13 centers across 11 states who presented with a chest pain syndrome and were referred for stress CMR were followed for a target period ...
Tópico(s): Medical Imaging Techniques and Applications
2019 - Elsevier BV | Journal of the American College of Cardiology
Panos Deloukas, M. E. Earthrowl, Darren Grafham, Marc Rubenfield, Lisa French, Charles A. Steward, Sarah Sims, Matthew C. Jones, S. Searle, Carol Scott, Kevin Howe, Sarah Hunt, T. Daniel Andrews, James Gilbert, David Swarbreck, Jennifer Ashurst, Amy Taylor, J K Battles, Christine Bird, R. Ainscough, J. P. Almeida, R. I. S. Ashwell, K. D. Ambrose, Anne Babbage, C. L. Bagguley, J. Bailey, Ruby Banerjee, K. Bates, Helen Beasley, S. Bray-Allen, Andrew Brown, J. Y. Brown, D. C. Burford, W. Burrill, J.H. Burton, Patrick Cahill, D. Camire, N. P. Carter, J. C. Chapman, S. Y. Clark, Geraldine M Clarke, Chris M. Clee, S. Clegg, N. Corby, Alan Coulson, Pawandeep Dhami, Ireena Dutta, Matt Dunn, L. Faulkner, Adam Frankish, Julie Frankland, P. Garner, J. Garnett, Susan Gribble, Chris Griffiths, Russell Grocock, Erik Gustafson, S. Austin Hammond, Joanna Harley, Elizabeth A. Hart, P. D. Heath, T. P. Ho, Barbara Hopkins, Jane Anne Horne, Philip Howden, Elizabeth J. Huckle, Catherine Hynds, Christopher M. Johnson, David J. Johnson, A. Kana, Mike Kay, A. M. Kimberley, J. K. Kershaw, Maria Kokkinaki, Gavin K. Laird, Stephanie Lawlor, H. M. Lee, Daniel Leongamornlert, Gavin K. Laird, Christine Lloyd, David Lloyd, Jane Loveland, J. Lovell, Stuart McLaren, K. E. McLay, Amanda A. McMurray, M. Mashreghi-Mohammadi, L. Matthews, Sarah Milne, T. Nickerson, Minh Quang Nguyen, E. K. Overton-Larty, Sophie Palmer, A. V. Pearce, A. I. Peck, Sarah Pelan, Benjamin Phillimore, Keith Porter, Catherine M. Rice, Andrea Rogosin, M. T. Ross, Theologia Sarafidou, Harminder Sehra, R. Shownkeen, C. D. Skuce, Michelle Smith, Lorraine S. Standring, Neil Sycamore, J. Tester, A. Thorpe, W. Torcasso, Alan Tracey, A. Tromans, Jason M. Tsolas, M. Wall, Justine Walsh, H. Wang, Keith G. Weinstock, Anthony P. West, David L. Willey, Siobhan Whitehead, Laurens Wilming, P. W. Wray, Lynn Young, Y. Chen, Ruth C. Lovering, Nicholas Κ. Moschonas, Reiner Siebert, Kim Fechtel, D. R. Bentley, Richard Durbin, Tim Hubbard, Lynn Doucette‐Stamm, Stephan Beck, Doug Smith, Jane Rogers,
Tópico(s): Genomic variations and chromosomal abnormalities
2004 - Nature Portfolio | Nature
Toru Takahashi, Hiroko Shimizu, Kazuyoshi Inoue, Hiroshi Morimatsu, Kana Umeda, Emiko Omori, Reiko Akagi, Kiyoshi Morita,
昨今の生命科学の進歩は薬理学の研究をより病態に応じた新薬の開発へと向かわせている.しかし,肝不全,腎不全,多臓器不全など,急性臓器不全は高い死亡率を示すにもかかわらず,その治療において決め手となる薬物は未だ開発されていない.これら急性臓器不全の組織障害の病態生理は完全に明らかでないが,好中球の活性化や虚血・再潅流にともなう酸化ストレスによる細胞傷害が大きな役割を果たしている.酸化ストレスはヘムタンパク質からヘムを遊離させる.遊離ヘムは脂溶性の鉄であることから,活性酸素生成を促進して細胞傷害を悪化させる.この侵襲に対抗するために,ヘム分解の律速酵素:Heme Oxygenase-1(HO-1)が細胞内に誘導される.HO-1によるヘム分解反応産物である一酸化炭素,胆汁色素には,抗炎症・抗酸化作用がある.したがって,遊離ヘム介在性酸化ストレスよって誘導されたHO-1は酸化促進剤である遊離ヘムを除去するのみならず,これらの代謝産物の作用を介して細胞保護的に機能する.一方,HO-1の発現抑制やHO活性の阻害は酸化ストレスによる組織障害を悪化させる.この,HO-1の細胞保護作用に着目して,HO-1誘導を酸化ストレスによる組織障害の治療に応用する試みがなされている. ...
Tópico(s): Hemoglobin structure and function
2007 - Japanese Pharmacological Society | Folia Pharmacologica Japonica
Hiroshi Orihara, Kana Tanabu, Yang Ho Na,
Tópico(s): Electrohydrodynamics and Fluid Dynamics
2008 - Physical Society of Japan | Journal of the Physical Society of Japan
Pang Li, Eric Stahl, Kana Fujikura, Michelle Chen, Weijia Li, Ming Zhang, Jeffrey M. Levsky, Mark I. Travin, Edwin Ho, Ythan Goldberg, Cynthia C. Taub,
(1) Background: This study sought to explore how the novel coronavirus (COVID-19) pandemic affected the echocardiography (TTE) laboratory operations at a high volume medical center in New York City. Changes in cardiac imaging study volume, turn-around time, and abnormal findings were analyzed and compared to a pre-pandemic period. (2) Methods: Volume of all cardiac imaging studies and TTE reports between 11 March 2020 to 5 May 2020 and the same calendar period in 2019 were retrospectively identified ...
Tópico(s): Ultrasound in Clinical Applications
2020 - Multidisciplinary Digital Publishing Institute | Healthcare
Sho Uchida, Shunsuke Uno, Masahiro Kondo, Yoshifumi Uwamino, Ho Namkoong, Tomoyasu Nishimura, Kana Misawa, Shoko Kashimura, Kei Yamato, Tamami Ishizaka, Kengo Nagashima, Yuko Kitagawa, Naoki Hasegawa,
Abstract Understanding the factors that influence people’s decisions regarding vaccination is essential to promote vaccination. We aimed to clarify the motivations for receiving booster vaccines. We conducted a paper-based questionnaire distributed during January–February 2022 involving students and faculty staff who received the first COVID-19 vaccination at the mass vaccination program during June–September 2021 at Keio University. A total of 1725 participants were enrolled, and all completed ...
Tópico(s): Psychology of Moral and Emotional Judgment
2024 - Nature Portfolio | Scientific Reports
Richard C. Centore, Luis M. Soares, Rishi G. Vaswani, Kana Ichikawa, Zhifang Li, Hong Fan, J.W. Setser, David L. Lahr, Laura E. Zawadzke, Xueying Chen, Kimberly D. Barnash, Jordana Muwanguzi, Neville J. Anthony, Gabriel J. Sandoval, Katharine Feldman, Ammar Adam, David C.S. Huang, Shawn Schiller, Kevin Wilson, Johannes Voigt, Martin Hentemann, David S. Millan, Ho Man Chan, Steven F. Bellon, Carl P. Decicco, Lan Xu,
... C. Centore, Luis M. Soares, Rishi G. Vaswani, Kana Ichikawa, Zhifang Li, Hong Fan, Jeremy Setser, David L. Lahr, Laura Zawadzke, Xueying Chen, Kimberly D. Barnash, Jordana Muwanguzi, Neville Anthony, Gabriel J. Sandoval, Katharine Feldman, Ammar Adam, David Huang, Shawn Schiller, Kevin Wilson, Johannes Voigt, Martin Hentemann, David S. Millan, Ho Man Chan, Steven F. Bellon, Carl P. Decicco, ...
Tópico(s): Cancer Mechanisms and Therapy
2021 - American Association for Cancer Research | Cancer Research
Manuel Perea, Chie Nakatani, Cees van Leeuwen,
... we conducted a silent reading experiment in Japanese Kana—a script in which orthography and phonology can ... preview was a replacement-mora nonword (a.ka.ho.ka [アカホカ] –a.me.ri.ka [アメリカ]). More ...
Tópico(s): Hearing Impairment and Communication
2010 - Springer Science+Business Media | Memory & Cognition
Shin-ichiro KANA, Jeong-Eun Cheon, Koon Ho Rha, Y.G. Lee, Tae-Jung Kwon, S.C. Park, Sungwoo Kang, Seung-Yong Jung, Ki-Woong Sung, H.H. Kim,
Tópico(s): Urological Disorders and Treatments
2010 - Elsevier BV | European Urology Supplements
Hankil Lee, Jun Yong Park, Ho Kim, Kana Kawagishi, Kaoru Yokoyama, Kiyonori Kobayashi, E Kim, Byung Ik Jang, K Kim, E Kim, Soyoung Jeon, H Lee, Jun Heo, Yong‐Jae Lee,
during a thromboembolic event.Thromboembolic events occurred in 5 (86%) of the 7 patients with thrombophilia, and 1 in a patient without thrombophilia.In addition, 4 ischaemic strokes, 1 central retinal artery thrombosis, 1 venous sinus thrombosis, 1 jugular venous thrombosis, and 1 transient ischaemic attack were recorded.In addition, 1 patient showed positive anti-β2 microglobulin antibody; 3 showed positive lupus anticoagulant with MTHFR C677T homozygosity; 1 MTHFR C677T homozygosity, 1 positive ...
Tópico(s): Diverticular Disease and Complications
2016 - Oxford University Press | Journal of Crohn s and Colitis
Kana Umeda, Toru Takahashi, Kazuyoshi Inoue, Hiroko Shimizu, Shigeru Maeda, Hiroshi Morimatsu, Emiko Omori, Reiko Akagi, Hiroshi Katayama, Kiyoshi Morita,
... that causes intestinal tissue injury. Heme oxygenase 1 (HO-1) is induced by oxidative stress and is ... induced tissue injury site in the intestine because HO-1 induction is the lowest at this site. ... also previously demonstrated that glutamine (GLN) significantly induced HO-1 in the lower intestinal tract. In the ... induced intestinal tissue injury in the ileum by HO-1 induction. Treatment of rats with GLN (0.75 g/kg, i.v.) markedly induced functional HO-1 protein in mucosal epithelial cells in the ... treatment with tin mesoporphyrin, a specific inhibitor of HO activity, abolished the beneficial effect of GLN pretreatment. ...
Tópico(s): Thermal Regulation in Medicine
2008 - Lippincott Williams & Wilkins | Shock