Rainer Glaser, Mary Beth Jost,
... the thermochemistry and of the kinetics of the HOBrO disproportionation reaction 2HOBrO (2) ⇄ HOBr (1) + HBrO(3) ( ... reaction and considering the acidities of HBr and HOBrO(2). The structures were determined of ten dimeric aggregates 4 of bromous acid, (HOBrO)(2), of eight mixed aggregates 5 formed between the products of disproportionation, (HOBr)(HOBrO(2)), and of four transition states structures 6 ... It was found that the condensation of two HOBrO molecules provides facile access to bromous acid anhydride ...
Tópico(s): Molecular spectroscopy and chirality
2012 - American Chemical Society | The Journal of Physical Chemistry A
Sujata Guha, Joseph S. Francisco,
... state for the process of isomerization of HOOBr→HOBrO has been located theoretically, using ab initio molecular ... not to facilitate the isomerization of HOOBr to HOBrO.
Tópico(s): Advanced Chemical Physics Studies
2000 - Elsevier BV | Chemical Physics Letters
Sujata Guha, Joseph S. Francisco,
... barrier for the isomerization of HOOBr to form HOBrO is high enough (67.2 kcal mol−1) to not allow the interconversion of HOOBr to HOBrO (and vice versa). Thus, HOOBr and HOBrO are the intermediates that can be formed during ...
Tópico(s): Industrial Gas Emission Control
1999 - Elsevier BV | Chemical Physics
Michael S. Block, Brian G. Rowan,
... PubMed Scopus (164) Google Scholar, 33Mourad K.A. Hobro S. Developing chlorine-based antiseptic by electrolysis.Sci ... iodinated salt, water, and electricity,33Mourad K.A. Hobro S. Developing chlorine-based antiseptic by electrolysis.Sci ...
Tópico(s): Retinal and Optic Conditions
2020 - Elsevier BV | Journal of Oral and Maxillofacial Surgery
Cristina Maria P. Santos, Roberto B. Faria, Juan O Machuca-Herrera, Sérgio de Paula Machado,
... K, present the following order: HOBr < HBrO; HOOBr < HOBrO < HBrO 2 ; HOOOBr < HOBrO 2 < HOOBrO < HBrO 3 . The HBrO x heat ...
Tópico(s): Atmospheric Ozone and Climate
2001 - NRC Research Press | Canadian Journal of Chemistry
James Hobro, S. C. Singh, T. A. Minshull,
A tomographic inversion method is presented for the determination of 3-D velocity and interface structure from a wide range of body-wave seismic traveltime data types. It is applicable to refraction, wide-angle reflection, normal-incidence and multichannel seismic data, and is best suited to a combination of these that provides good independent constraints on seismic velocities and interface depths. The inversion process seeks a layer–interface minimum-structure model that is able to explain the ...
Tópico(s): Methane Hydrates and Related Phenomena
2003 - Oxford University Press | Geophysical Journal International
Khaldoon A. Mourad, Sture Hobro,
The use of Alcohol-based antiseptics is efficient and approved, however it has some limitations. This paper examined the possibility of using hypochlorite water as a chlorine-based antiseptic for handwashing in public buildings and healthcare facilities. The electrolysis method was used, which produces Hypochlorous acid (HOCl) from mixing drinking water with small amounts of sodium hydroxide. Hypochlorous acid is usually produced by blood cells to surround pathogens when the skin is cut and exposed ...
Tópico(s): Healthcare and Environmental Waste Management
2019 - Elsevier BV | The Science of The Total Environment
Nicolas Pavillon, Alison J. Hobro, Shizuo Akira, Nicholas I. Smith,
We present a method enabling the noninvasive study of minute cellular changes in response to stimuli, based on the acquisition of multiple parameters through label-free microscopy. The retrieved parameters are related to different attributes of the cell. Morphological variables are extracted from quantitative phase microscopy and autofluorescence images, while molecular indicators are retrieved via Raman spectroscopy. We show that these independent parameters can be used to build a multivariate ...
Tópico(s): Image Processing Techniques and Applications
2018 - National Academy of Sciences | Proceedings of the National Academy of Sciences
Alison J. Hobro, Nicholas I. Smith,
Although live cell imaging is desirable, it is not always feasible and in many situations cells are fixed in order to provide a 'snapshot' of the nature and distribution of molecules within a cell while minimising changes from cell movement, sample degradation etc. There is a wide range of fixation methods available that act via different mechanisms, and on different cell components. Each method has advantages and disadvantages and a choice of what fixation method to choose for a particular experiment ...
Tópico(s): Ion-surface interactions and analysis
2016 - Elsevier BV | Vibrational Spectroscopy
Alison J. Hobro, Yutaro Kumagai, Shizuo Akira, Nicholas I. Smith,
Unactivated lymphocytes are morphologically identical and biochemically relatively similar, making them difficult to distinguish from one another with conventional light microscopy. Here, we use Raman spectroscopy to provide biochemical information on the composition of different lymphocyte cell lines. As could be expected, the biochemical differences measured with Raman spectroscopy between lymphocyte cell lines are small, but in combination with partial least squares discriminant analysis it is ...
Tópico(s): Digital Imaging for Blood Diseases
2016 - Royal Society of Chemistry | The Analyst
Alison J. Hobro, Nicolas Pavillon, Katsumasa Fujita, Müge Özkan, Cevayir Coban, Nicholas I. Smith,
Raman spectroscopy highlights biochemical changes that are spectrally or spatially related to the presence of the malaria pigment, hemozoin, inside macrophage cells, during the initial stages of exposure.
Tópico(s): Malaria Research and Control
2015 - Royal Society of Chemistry | The Analyst
Chris Chapman, James Hobro, Johan O. A. Robertsson,
Finite-difference simulations are an important tool for studying elastic and acoustic wave propagation, but remain computationally challenging for elastic waves in three dimensions. Computations for acoustic waves are significantly simpler as they require less memory and operations per grid cell, and more significantly can be performed with coarser grids, both in space and time. In this paper, we present a procedure for correcting acoustic simulations for some of the effects of elasticity, at a ...
Tópico(s): Geophysical Methods and Applications
2014 - Oxford University Press | Geophysical Journal International
James Hobro, Chris Chapman, Johan O. A. Robertsson,
We present a new method for correcting the amplitudes of arrivals in an acoustic finite-difference simulation for elastic effects. In this method, we selectively compute an estimate of the error incurred when the acoustic wave equation is used to approximate the behavior of the elastic wave equation. This error estimate is used to generate an effective source field in a second acoustic simulation. The result of this second simulation is then applied as a correction to the original acoustic simulation. ...
Tópico(s): Geophysical Methods and Applications
2014 - Society of Exploration Geophysicists | Geophysics
Nicholas I. Smith, Kentaro Mochizuki, Hirohiko Niioka, Satoshi Ichikawa, Nicolas Pavillon, Alison J. Hobro, Jun Ando, Katsumasa Fujita, Yutaro Kumagai,
Nanoparticle manipulation is of increasing interest, since they can report single molecule-level measurements of the cellular environment. Until now, however, intracellular nanoparticle locations have been essentially uncontrollable. Here we show that by infusing a gold ion solution, focused laser light-induced photoreduction allows in situ fabrication of gold nanoparticles at precise locations. The resulting particles are pure gold nanocrystals, distributed throughout the laser focus at sizes ranging ...
Tópico(s): Photoreceptor and optogenetics research
2014 - Nature Portfolio | Nature Communications
Alison J. Hobro, Daron M. Standley, Shandar Ahmad, Nicholas I. Smith,
RNA molecules are involved in many pathways within the cell and their sequence composition, structure, conformational transitions and interactions with other molecules are all important factors in determining RNA function. Here we present a method for systematically and quantitatively determining characteristics of RNA using Raman spectroscopy. This method can be used to assess the composition and structure of a given RNA molecule, including ribose-phosphate sugar-pucker conformation, face-to-face ...
Tópico(s): thermodynamics and calorimetric analyses
2013 - Royal Society of Chemistry | Physical Chemistry Chemical Physics
Nicolas Pavillon, Alison J. Hobro, Nicholas I. Smith,
Abstract We show how Raman imaging can be combined with independent but simultaneous phase measurements of unlabeled cells, with the resulting data providing information on how the light is retarded and/or scattered by molecules in the cell. We then show, for the first time to our knowledge, how the chemistry of the cell highlighted in the Raman information is related to the cell quantitative phase information revealed in digital holographic microscopy by quantifying how the two sets of spatial information ...
Tópico(s): Cell Image Analysis Techniques
2013 - Elsevier BV | Biophysical Journal
Alison J. Hobro, Aki Konishi, Cevayir Coban, Nicholas I. Smith,
In this study Raman spectroscopy has been used to monitor the changes in erythrocytes and plasma during Plasmodium infection in mice, following malaria disease progression over the course of 7 days. The Raman spectra of both samples are dominated by the spectra of hemoglobin and hemozoin, due to their resonant enhancement. In plasma samples, due to the inherently low heme background, heme-based changes in the Raman spectra could be detected in the very early stages of infection, as little as one ...
Tópico(s): Bee Products Chemical Analysis
2013 - Royal Society of Chemistry | The Analyst
Katherine Lau, Alison J. Hobro, Tim Smith, Thomas Thurston, Bernhard Lendl,
Here we present Fourier transform infrared (FTIR) and Raman images of Steinernema kraussei nematode worms and, in conjunction with chemometric analysis. We also distinguished the biochemical differences associated with different regions of these images. The nematodes are complex, multicellular organisms that have a simple, but defined body plan with distinct digestive, muscular and reproductive systems. As such, nematodes have often been used as model organisms for the study of biological processes ...
Tópico(s): thermodynamics and calorimetric analyses
2012 - Elsevier BV | Vibrational Spectroscopy
Muhammad Rafique, Shazia Bashir, W. Husinsky, Alison J. Hobro, Bernhard Lendl,
Ultra fast electronic and thermal processes for energy deposition mechanism during femtosecond laser ablation of CaF2 have been identified by means of Atomic Force Microscopy (AFM) and Raman scattering technique. For this purpose, a single crystal CaF2 (1 1 1) was exposed with 800 nm, 25 fs Ti: Sapphire laser pulses at different laser fluences both in air and under UHV condition. Various nano and microstructures on the surface of the irradiated samples are revealed by a detailed surface topography ...
Tópico(s): Laser Material Processing Techniques
2011 - Elsevier BV | Applied Surface Science
Bernhard Zachhuber, Georg Ramer, Alison J. Hobro, Engelene t. H. Chrysostom, Bernhard Lendl,
Tópico(s): Laser-induced spectroscopy and plasma
2011 - Springer Science+Business Media | Analytical and Bioanalytical Chemistry
Nobuyuki Akai, Daisuke Wakamatsu, Takeo Yoshinobu, Akio Kawai, Kazuhiko Shibuya,
Tópico(s): Spectroscopy and Laser Applications
2010 - Elsevier BV | Chemical Physics Letters
Alison J. Hobro, Julia Kuligowski, Markus Döll, Bernhard Lendl,
Tópico(s): Wood and Agarwood Research
2010 - Springer Science+Business Media | Analytical and Bioanalytical Chemistry
Alison J. Hobro, Bernhard Lendl,
Stand-off Raman spectroscopy, where the instrumentation is physically separated from the sample under investigation, can be extremely advantageous for analysis of dangerous, fragile or inaccessible samples. We first review common aspects of stand-off Raman instruments, including laser, optical lay-out, wavelength dispersion and detection, and how their characteristics can affect overall performance. We then provide an overview of applications of stand-off Raman spectroscopy in different fields, ...
Tópico(s): Laser-induced spectroscopy and plasma
2009 - Elsevier BV | TrAC Trends in Analytical Chemistry
Sara Wallin, Anna Pettersson, Henric Östmark, Alison J. Hobro,
Tópico(s): Terahertz technology and applications
2009 - Springer Science+Business Media | Analytical and Bioanalytical Chemistry
Alison J. Hobro, Mansour Rouhi, Graeme L. Conn, Ewan W. Blanch,
Abstract Raman and Raman optical activity (ROA) spectroscopies are well suited to the study of ribonucleic acids (RNA) as they are both sensitive to a large amount of structural information and applicable to most RNAs and experimental conditions. As such, they can fill the current gap between high- and low-resolution techniques currently used by RNA biologists. In this study we illustrate the complementarity of Raman and ROA spectroscopies by their application to two functional RNAs, a 37 nucleotide ...
Tópico(s): Viral Infections and Immunology Research
2007 - Elsevier BV | Vibrational Spectroscopy
Alison J. Hobro, M. Rouhi, Ewan W. Blanch, Graeme L. Conn,
Raman and Raman optical activity (ROA) spectra were collected for four RNA oligonucleotides based on the EMCV IRES Domain I to assess the contributions of helix, GNRA tetraloop, UÁC mismatch base pair and pyrimidine-rich bulge structures to each.Both Raman and ROA spectra show overall similarities for all oligonucleotides, reflecting the presence of the same base paired helical regions and GNRA tetraloop in each.Specific bands are sensitive to the effect of the mismatch and asymmetric bulge on the ...
Tópico(s): DNA and Nucleic Acid Chemistry
2007 - Oxford University Press | Nucleic Acids Research
Steven M. Reddy, Nicholas E. Timms, Patrick Trimby, Peter D. Kinny, Craig Buchan, Kevin Blake,
... Trimby 2HKL Technology A/S, Majsmarken 1, 9500 Hobro, Denmark Search for other works by this author ...
Tópico(s): High-pressure geophysics and materials
2006 - Geological Society of America | Geology
James Hobro, T. A. Minshull, S. C. Singh, Shyam Chand,
Methane hydrate bottom‐simulating reflectors (BSRs) are widespread on the northern Cascadia margin offshore Vancouver Island. We conducted a three‐dimensional tomographic seismic study of the hydrate stability zone in an area around Ocean Drilling Program Site 889 using two deployments of five ocean bottom hydrophones and air gun shots along a series of closely spaced profiles in various orientations. Further constraints on reflector geometry come from coincident single‐channel reflection profiles. ...
Tópico(s): Seismic Waves and Analysis
2005 - American Geophysical Union | Journal of Geophysical Research Atmospheres
Cristina Dal Bosco, Lina Lezhneva, Alexander Biehl, Dario Leister, Heinrich Strotmann, G. Wanner, Jörg Meurer,
... plants were efficiently selected on rock wool (Grodan, Hobro, Denmark) immersed in 10 mg/liter sulfadiazine prior ...
Tópico(s): Mitochondrial Function and Pathology
2004 - Elsevier BV | Journal of Biological Chemistry
Nadine Solveig Hobro, John Weinman, Matthew Hankins,
The pain literature indicates that, despite extensive investigations and recommendations, treatment outcomes can be poor. This study assesses whether a theoretical approach using the self-regulatory model (SRM) could usefully categorise chronic pain patients on the basis of their illness representations, since these have been shown to influence outcomes for other health-related conditions. One hundred and thirty newly referred patients of a pain relief clinic completed the revised Illness Perceptions ...
Tópico(s): Mindfulness and Compassion Interventions
2004 - Lippincott Williams & Wilkins | Pain