Jiuan-Miaw Liao, Chih-Feng Lin, Hua Ting, Chi-Chen Chang, Yuh-Jeng Lin, Tzer-Bin Lin,
... investigated in alpha-chloralose anesthetized rats. The acupoint: Hoku (Li-4) was tested with two different stimulation ... elevation of BP were elicited during Ea at Hoku with stimulation intensity of 20 times of motor ... in this study implicated that: (1) Ea at Hoku may activate the sympathetic and simultaneously inhibit the gastric parasympathetic nerve; (2) Ea at Hoku with different stimulation frequencies may elicit distinct mechanism to induce therapeutic effect; (3) Ea at Hoku may ameliorate the hyperactive stomach in clinical therapy.
Tópico(s): Healthcare and Venom Research
2002 - Elsevier BV | Neuroscience Research
Tzer‐Bin Lin, Tsu‐Ching Fu, Chau-Fong Chen, Yuh-Jeng Lin, Chiang-Ting Chien,
... were investigated in urethane-anesthetized rats. The acupoint Hoku (Li-4) was tested with two different stimulation ... BP and RNA was elicited during Ea at Hoku. However, the pressor response induced by low frequency ... HFEa. These results imply that: (1) Ea at Hoku may selectively activate the sympathetic, but not the parasympathetic nervous system, (2) Ea at Hoku with a different stimulation frequency may elicit a ... the sympathetic nervous system and (3) Ea at Hoku may ameliorate the hyperactive bladder in clinical therapy.
Tópico(s): Healthcare and Venom Research
1998 - Elsevier BV | Neuroscience Letters
Tahmineh Salehian, Faranak Safdari Dehcheshmaei, Arezoo Pirak, Afsaneh. Kazemian, Zahra Atarodi, Shahin Dokht Navabi Righi,
... this study was to compare the effect of Hoku Point (LI4) acupressure and San-Yin-Jiao (SP6) ... randomly assigned into 3 equivalent groups (n=30): Hoku, SanYinJiao and control groups. Data of each woman ... for 20 minutes on two feet during contractions. Hoku group received acupressure at Hoku Point (over the area of the web of ...
Tópico(s): Pediatric Pain Management Techniques
2011 - | Scientific Journal of Kurdistan University of Medical Sciences
F Safdari Dehcheshmeh, Hossein Rafiei,
... non-pharmacological pain relief methods "music therapy" and "Hoku point ice massage" on the severity of labor ... group "A" received music therapy, group "B" received Hoku point ice massage, and group "C" received usual ... statistically significant (P > 0.05). Music therapy and Hoku point ice massage are easily available and inexpensive ...
Tópico(s): Anesthesia and Pain Management
2015 - Elsevier BV | Complementary Therapies in Clinical Practice
Hua Ting, Jiuan-Miaw Liao, Chih-Feng Lin, Ping-Yen Chiang, Chi-Chen Chang, Dong-Yih Kuo, Tzer-Bin Lin,
... hemorrhage was investigated in anesthetized rats. Two acupoints, Hoku (Li-4, at the junction of the first ... 20 Hz). In the intact state, Ea at Hoku elicited an elevation of BP in parallel with ... by a low frequency Ea (2 Hz) at Hoku was different than a high frequency one (20 ... conditions. All the results suggested that Ea at Hoku with appropriate stimulation parameters can increase and maintain ...
Tópico(s): Pain Mechanisms and Treatments
2002 - Elsevier BV | Neuroscience Letters
... investigated in anesthetized rats. Tsusanli (St-36) and Hoku (Li-4) were tested with combinations of two ... At Tsusanli, no effect was found, while at Hoku, an elevation of BP in parallel with ANA ... high frequency Ea (HFEa, 30 Hz). When both Hoku were simultaneously stimulated with the same frequency, the ... concluded that a LFEa and a HFEa at Hoku with appropriate stimulation parameters can increase BP which ...
Tópico(s): Pain Mechanisms and Treatments
2000 - Elsevier BV | Neuroscience Letters
... Circular Cross Section H. Ito¯, H. Ito¯ To¯hoku University, Sendai, Japan Search for other works by ... PubMed Google Scholar K. Imai K. Imai To¯hoku University, Sendai, Japan Search for other works by ... Scholar Author and Article Information H. Ito¯ To¯hoku University, Sendai, Japan K. Imai To¯hoku University, Sendai, Japan J. Basic Eng. Sep 1966, ...
Tópico(s): Vibration and Dynamic Analysis
1966 - American Society of Mechanical Engineers | Journal of Basic Engineering
Junfa Wang, Oluwasegun Olamide Fawibe, Kehinde Oluwaseyi Fawibe, Akihiro Isoda,
... Togohybrid 4 (Togo), Himenomochi (Hime), Akidawara (Aki), Hokuriku193 (Hoku), and Bekoaoba (Beko) were evaluated in a 2-year field experiment. Hoku and Beko are multipurpose high-yielding varieties that ... filling period are necessary. Also, the multipurpose varieties (Hoku and Beko) could be cultivated under DI in ...
Tópico(s): Irrigation Practices and Water Management
2022 - Elsevier BV | Field Crops Research
Hsin Hsiu, Wei-Chen Hsu, Bo‐Hung Chen, Chia-Liang Hsu,
... effects of contact pressure stimulation (PS) underneath the Hoku acupoint and its nearby nonacupoint, to improve the ... applied PS (group A, 60 mmHg on the Hoku acupoint; group B, 60 mmHg on a nearby ... B. The improved microcirculatory blood-flow perfusion at Hoku may partly explain why acupressure can exert better ...
Tópico(s): Myofascial pain diagnosis and treatment
2010 - IOP Publishing | Physiological Measurement
Jiuan-Miaw Liao, Hua Ting, Shin‐Da Lee, Chao-Hsun Yang, Ying‐Ming Liou, Mei-Lin Peng, Shih-Jei Tsai, Chih-Feng Lin, Tzer-Bin Lin,
... at the Tsusanli point (St-36) and the Hoku point (Li-4) were tested by a low ... point was stimulated. Whereas, Ea stimulations at the Hoku point elicit chronotropic and pressor effects. The patterns ... effects. We concluded that Ea stimulations, at the Hoku acupoint, with appropriate stimulation parameters can increase and ...
Tópico(s): Healthcare and Venom Research
2006 - Elsevier BV | Autonomic Neuroscience
Tsun-Cheng Kuo, Chii‐Wann Lin, Feng‐Ming Ho,
... medical student volunteers were given acupuncture at the Hoku (LI-4) acupoint as they were resting. During ... show continuous increase of blood flow as did Hoku. Hoku acupuncture also increased palm temperature suggesting that the ...
Tópico(s): Traditional Chinese Medicine Studies
2004 - World Scientific | The American Journal of Chinese Medicine
Monique Ernst, Mathew H.M. Lee,
... procedure used in a previous study using the Hoku hand point. A generalized long-lasting warming (sympathetic ... effect is consistent with the results of the Hoku study and appears to be a central sympathetic ...
Tópico(s): Pain Mechanisms and Treatments
1986 - Elsevier BV | Experimental Neurology
Nobuari Takakura, Arata Kanamaru, Masato Sibuya, Ikuo Homma,
... stainless steel needle was inserted into the right Hoku point and remained inserted (in-situ technique) for ... was significantly decreased by acupuncture at the right Hoku point (% control force of VFR: right, 67.8.%; ...
Tópico(s): Effects of Vibration on Health
1992 - World Scientific | The American Journal of Chinese Medicine
Patrick Karjala, Dean Lodes, Kari Noe, Anna Sikkink, Jason Leigh,
... non-instrument navigators. The first implementation of Kilo Hōkū as a cultural heritage project in virtual reality ...
Tópico(s): Simulation and Modeling Applications
2017 - The MIT Press | PRESENCE Virtual and Augmented Reality
Hsin Hsiu, Wei-Chen Hsu, Chia-Liang Hsu, Shih-Ming Huang, Yuh-Ying Wang Lin,
... responses to the application of homogeneous LH at Hoku and two nearby nonacupoints.Thirty-four trials were ... flux increase following LH were all largest at Hoku.Our results suggest that the application of LH ...
Tópico(s): Infrared Thermography in Medicine
2009 - Mary Ann Liebert, Inc. | Photomedicine and Laser Surgery
Naoya Hamaue, Masaru Minami, Masahiko Hirafuji, Mutsuko Terado, Minoru Machida, Noriko Yamazaki, Mitsuhiro Yoshioka, Akihiko Ogata, Kunio Tashiro,
... Fax: 81-1332-3-1669. E-mail: minami@hoku-iryo-u.ac.jpSearch for more papers by ... Fax: 81-1332-3-1669. E-mail: minami@hoku-iryo-u.ac.jpSearch for more papers by ...
Tópico(s): Synthesis of Organic Compounds
1999 - Wiley | CNS Drug Reviews
Nobuari Takakura, Hajime Ogawa, Satoshi Iijima, Keiichi Nishimura, Arata Kanamaru, Masato Sibuya, Ikuo Homma,
... and after acupuncture. Acupuncture was applied to the Hoku point on both sides. The three techniques, each ...
Tópico(s): Effects of Vibration on Health
1995 - World Scientific | The American Journal of Chinese Medicine
... stimulation as compared to placebo stimulation of the HoKu point in 50 patients suffering acute oro-facial ... study showed that extrasegmental superficial stimulation of the HoKu point alters pain intensity in the patients studied ...
Tópico(s): Myofascial pain diagnosis and treatment
1985 - Lippincott Williams & Wilkins | Pain
Monique Ernst, Mathew H.M. Lee,
... and electrical acupuncture applied to the same hand (Hoku) point. Thermographie measures of superficial skin temperature were ...
Tópico(s): Pain Mechanisms and Treatments
1985 - Lippincott Williams & Wilkins | Pain
Yasuo Gomi, Hiroaki Shirahase, Hideyuki Funato,
... 2-chloro-4-hydroxyphenyl)-2-t-butylaminoethanol hydrochloride (HOKU-81), one of the metabolites of tulobuterol, on ... induced relaxation were in the order of: trimetoquinol>HOKU-81 ^isoproterenol > salbutamol > terbutaline tulobuterol > metaproterenol > clorprenaline. In ... or 3,5-dihydroxyphenyl derivatives and that of HOKU-81,2-chloro-4-hydroxyphenyl derivative, lay between two groups. HOKU-81 showed weak positive chronotropic and inotropic actions and the potency ratio of HOKU-81 to isoproterenol was about 3/100 and ...
Tópico(s): Radical Photochemical Reactions
1979 - Japanese Pharmacological Society | The Japanese Journal of Pharmacology
Elham Davtalab, Sayedali Naji, Shahrzad Shahidi,
... effects of Valsalva maneuver and ice massage at Hoku point on pain intensity during cannulation of arteriovenous ...
Tópico(s): Family and Patient Care in Intensive Care Units
2016 - Sumathi Publications | International Journal of Medical Research & Health Sciences
Nobuari Takakura, Majime Ogawa, Satoshi Iijima, Keiichi Nishimura, Arata Kanamaru, Masato Sibuya, Ikuo Momma,
... finger tip. The acupuncture point was the right Hoku point. Both techniques of acupuncture inhibited VFR in ...
Tópico(s): Myofascial pain diagnosis and treatment
1993 - World Scientific | The American Journal of Chinese Medicine
Masayoshi Tsuruoka, Yoshio Yamakami,
... from the different dermatomes, the Zusanli and the Hoku, was compared using the tail flick reflex in ... not antagonized by naloxone (1 mg/kg). The Hoku stimulation also produced the suppression of the EMG ...
Tópico(s): Sleep and Wakefulness Research
1987 - World Scientific | The American Journal of Chinese Medicine
Naimeh Porramezani, Zahra Imani Goghary, Maryam Firouzabadi, Mohadeseh Balvardi, Fatemeh Irannejad Parizi,
The Effect of Cryotherapy in the Hoku point on the Severity of Pain of Fistula Catheterization in Patients on Hemodialysis
Tópico(s): Anesthesia and Pain Management
2019 - | Journal of Advances in Medical and Biomedical Research
Qianru Jin, Anil Bhatta, Jayson V. Pagaduan, Xing Chen, Hoku West‐Foyle, Jiayu Liu, Annie Hou, Dan E. Berkowitz, Scot C. Kuo, Frederic B. Askin, Thao D. Nguyen, David H. Gracias, Lewis H. Romer,
Biofabricated mass-producible arteries containing layered and aligned cells and matrix exhibit enhanced cellular function.
Tópico(s): Bone Tissue Engineering Materials
2020 - American Association for the Advancement of Science | Science Advances
Alexandra Surcel, Eric S. Schiffhauer, Dustin Thomas, Qingfeng Zhu, Kathleen DiNapoli, Maik Herbig, Oliver Otto, Hoku West‐Foyle, Angela Jacobi, Martin Kräter, Katarzyna Plak, Jochen Guck, Elizabeth M. Jaffee, Pablo A. Iglesias, Robert A. Anders, Douglas N. Robinson,
Metastasis is complex, involving multiple genetic, epigenetic, biochemical, and physical changes in the cancer cell and its microenvironment. Cells with metastatic potential are often characterized by altered cellular contractility and deformability, lending them the flexibility to disseminate and navigate through different microenvironments. We demonstrate that mechanoresponsiveness is a hallmark of pancreatic cancer cells. Key mechanoresponsive proteins, those that accumulate in response to mechanical ...
Tópico(s): Microtubule and mitosis dynamics
2019 - American Association for Cancer Research | Cancer Research
Jr-Ming Yang, Sayak Bhattacharya, Hoku West‐Foyle, Chien‐Fu Hung, T.‐C. Wu, Pablo A. Iglesias, Chuan‐Hsiang Huang,
Abstract The Ras-ERK signaling pathway regulates diverse cellular processes in response to environmental stimuli and contains important therapeutic targets for cancer. Recent single cell studies revealed stochastic pulses of ERK activation, the frequency of which determines functional outcomes such as cell proliferation. Here we show that ERK pulses are initiated by localized protrusive activities. Chemically and optogenetically induced protrusions trigger ERK activation through various entry points ...
Tópico(s): thermodynamics and calorimetric analyses
2018 - Nature Portfolio | Nature Communications
Hoku West‐Foyle, Priyanka Kothari, Jonathan Osborne, Douglas N. Robinson,
The 14-3-3 family comprises a group of small proteins that are essential, ubiquitous, and highly conserved across eukaryotes. Overexpression of the 14-3-3 proteins σ, ɛ, ζ, and η correlates with high metastatic potential in multiple cancer types. In Dictyostelium, 14-3-3 promotes myosin II turnover in the cell cortex and modulates cortical tension, cell shape, and cytokinesis. In light of the important roles of 14-3-3 proteins across a broad range of eukaryotic species, we sought to determine how ...
Tópico(s): Ubiquitin and proteasome pathways
2018 - Elsevier BV | Journal of Biological Chemistry
Background Childbirth is one of the most painful experiences for women during their reproductive life. The aim of this study was to assess the effect of large intestine 4 (LI4) massage with ice on labor duration during the active phase of labor. A randomized controlled trial was adopted for this study. Mothers were recruited from the labor unit at El Manial University Maternity Hospital. A total of 200 laboring women were randomly selected after admission to the labor unit according to certain criteria. ...
Tópico(s): Maternal Mental Health During Pregnancy and Postpartum
2016 - Medknow | Egyptian Nursing Journal