Hokuto Kamon, Takaya Kawabe, Hidemitsu Kitamura, Jihye Lee, Daisuke Kamimura, Tsuneyasu Kaisho, Shizuo Akira, Akihiro Iwamatsu, Hisashi Koga, Masaaki Murakami, Toshio Hirano,
... that is critical for CD4 T-cell activation Hokuto Kamon Hokuto Kamon Laboratory of Developmental Immunology, Graduate School of ... Japan Search for more papers by this author Hokuto Kamon Hokuto Kamon Laboratory of Developmental Immunology, Graduate School of ... for more papers by this author Author Information Hokuto Kamon1,‡, Takaya Kawabe1,‡, Hidemitsu Kitamura2, Jihye Lee1, Daisuke ...
Tópico(s): Immunotherapy and Immune Responses
2006 - Springer Nature | The EMBO Journal
Hokuto Iwatani, Moriaki Yasuhara, Yair Rosenthal, Braddock K. Linsley,
... during the past 15,000 years: Ostracod evidence Hokuto Iwatani; Hokuto Iwatani * 1School of Biological Sciences and Swire Institute ... Pokfulam Road, Hong Kong SAR, China *E-mails: hokuto.iwatani@gmail.com; moriakiyasuhara@gmail.com Search for ... Pokfulam Road, Hong Kong SAR, China *E-mails: hokuto.iwatani@gmail.com; moriakiyasuhara@gmail.com Search for ... Tools Icon Tools Get Permissions Search Site Citation Hokuto Iwatani, Moriaki Yasuhara, Yair Rosenthal, Braddock K. Linsley; ...
Tópico(s): Maritime and Coastal Archaeology
2018 - Geological Society of America | Geology
Michihiko Aramaki, Isamu Hokuto, Tadashi Matsumoto, Hitoshi Ishimoto, Makoto Inoue, Takehiro Kimura, Yoichi Oikawa, Kazushige Ikeda, Yasunori Yoshimura, Takao Takahashi, Kenjiro Kosaki,
... Tokyo, JapanSearch for more papers by this authorIsamu Hokuto, Isamu Hokuto Department of Pediatrics, Keio University School of Medicine, ... Tokyo, JapanSearch for more papers by this authorIsamu Hokuto, Isamu Hokuto Department of Pediatrics, Keio University School of Medicine, ...
Tópico(s): Genomic variations and chromosomal abnormalities
2005 - Wiley | American Journal of Medical Genetics Part A
Nobuyoshi Kurihara, Masayuki Miwa, Yohei Matsuzaki, Isamu Hokuto, Haruto Kikuchi, Shinji Katano, Kazushige Ikeda,
... of NeonatologySearch for more papers by this authorIsamu Hokuto, Isamu Hokuto Department of Pediatrics, Division of NeonatologySearch for more ... of NeonatologySearch for more papers by this authorIsamu Hokuto, Isamu Hokuto Department of Pediatrics, Division of NeonatologySearch for more ...
Tópico(s): Congenital Heart Disease Studies
2011 - Wiley | Pediatrics International
Yasuo Takahashi, Hiroyuki Kubota, Sawako Shigeto, Takahiro Yoshida, Yoshiki Yamagata,
... of migration expressed by the migrants arrived in Hokuto City, a Japanese rural municipality experiencing pervasive population ... areas. Statistical analyses of 868 responses to a Hokuto City's migrant survey between April 2017 and ... values of migration to rural areas, such as Hokuto City, will be useful to inform regional land ...
Tópico(s): Urban Transport and Accessibility
2021 - Elsevier BV | Journal of Rural Studies
Shumpei P. Yasuda, Shusaku Minato, Koichiro Tsuchiya, Hitoshi Suzuki,
... this authorS. Minato, S. Minato KEEP Dormouse-Museum, Hokuto, JapanSearch for more papers by this authorK. Tsuchiya, ... this authorS. Minato, S. Minato KEEP Dormouse-Museum, Hokuto, JapanSearch for more papers by this authorK. Tsuchiya, ... protected], [email protected]; Shusaku Minato, KEEP Dormouse-museum, Hokuto 407-0311, Japan. E-mail: [email protected]; Kimiyuki ...
Tópico(s): Yersinia bacterium, plague, ectoparasites research
2007 - Wiley | Journal of Zoological Systematics & Evolutionary Research
Hiroko Ejiri, Yukita Sato, Kyeong Soon Kim, Yoshio Tsuda, Koichi Murata, Keisuke Saito, Yukiko Watanabe, Yoshiharu Shimura, Masayoshi Yukawa,
... Saito 5Institute for Raptor Biomedicine Japan, 2-2101 Hokuto, Kushiro, Hokkaido, Japan. Search for other works by ... Watanabe 5Institute for Raptor Biomedicine Japan, 2-2101 Hokuto, Kushiro, Hokkaido, Japan. Search for other works by ...
Tópico(s): Mosquito-borne diseases and control
2011 - Oxford University Press | Journal of Medical Entomology
Donald Massaro, G. D. Massaro,
... 20–27, 2004.Crossref | PubMed | ISI | Google Scholar20 Hokuto I, Perl AK, and Whitsett JA. Prenatal, but ... Times, April 19, 2003.Google Scholar43 Perl AK, Hokuto I, Impagnatiello MA, Christofori G, and Whitsett JA. ...
Tópico(s): Chronic Obstructive Pulmonary Disease (COPD) Research
2004 - American Physical Society | AJP Lung Cellular and Molecular Physiology
Hiroo Konishi, Ryo Tanaka, Toshiyuki Shiraki,
... tests are carried out in two sites of Hokuto City, Yamanashi Prefecture and Wakkanai City, Hokkaido. The ... targets and some of studying results of the Hokuto mega-solar project (HMSP) are introduced in this ...
Tópico(s): Photovoltaic Systems and Sustainability
2009 - Elsevier BV | Solar Energy Materials and Solar Cells
Masataro Hayakawa, Tomonori Nakano,
Abstract Das Quellsediment der Thermen von Hokuto, Taiwan besteht hauptsächlich wie schon bekannt aus Angleso‐Baryt, aber es enthält noch dazu die kleinen Mengen von Cer und Lanthan außer ...
Tópico(s): Metallurgy and Cultural Artifacts
1912 - Wiley | Zeitschrift für anorganische und allgemeine Chemie
Yasuo Takahashi, Takahiro Yoshida, Sawako Shigeto, Hiroyuki Kubota, Brian Johnson, Yoshiki Yamagata,
... urban to rural areas by studying residents in Hokuto City, a popular urban-to-rural migration destination ... way migrants, chose their present home location in Hokuto City, indicating their intention to increase QoL by ...
Tópico(s): Migration, Aging, and Tourism Studies
2024 - Springer Science+Business Media | Sustainability Science
Hokuto Ohtsuka, Kazuki Imada, Takafumi Shimasaki, Hirofumi Aiba,
Abstract The fission yeast Schizosaccharomyces pombe employs two main strategies to adapt to the environment and survive when starved for nutrients. The strategies employ sporulation via sexual differentiation and extension of the chronological lifespan. When a cell is exposed to nutrient starvation in the presence of a cell of the opposite sex, the cells undergo fusion through conjugation and sporulation through meiosis. S. pombe spores are highly resistant to diverse stresses and may survive for ...
Tópico(s): Biofuel production and bioconversion
2022 - Wiley | MicrobiologyOpen
Daichi Yamada, Masato Hiwatari, Daiju Narita, Peter Hangoma, Bona Chitah, Hokuto Nakata, Shouta M.M. Nakayama, John Yabe, Mayumi Ito, Toshifumi Igarashi, Mayumi Ishizuka, Golden Zyambo,
Lead (Pb) pollution has been one of the major environmental problems of worldwide significance. It is a latent factor for several fatal illnesses, whereas the exposure to lead in early childhood causes a lifetime IQ loss. The social cost is the concept to aggregate various adverse effects in a single monetary unit, which is useful in describing the pollution problem and provides foundation for the design of interventions. However, the assessment of the social cost is scarce for developing countries. ...
Tópico(s): Mining and Resource Management
2022 - Elsevier BV | The Science of The Total Environment
Hokuto Nakayama, Aaron R. Leichty, Neelima Sinha,
Abstrvact The basic mechanisms of leaf development have been revealed through a combination of genetics and intense analyses in select model species. The genetic basis for diversity in leaf morphology seen in nature is also being unraveled through recent advances in techniques and technologies related to genomics and transcriptomics, which have had a major impact on these comparative studies. However, this has led to the emergence of new unresolved questions about the mechanisms that generate the ...
Tópico(s): Plant and animal studies
2022 - Oxford University Press | The Plant Cell
We show how the families Seiberg-Witten invariants of a family of smooth $4$-manifolds can be recovered from the families Bauer-Furuta invariant via a cohomological formula. We use this formula to deduce several properties of the families Seiberg-Witten invariants. We give a formula for the Steenrod squares of the families Seiberg-Witten invariants leading to a series of mod $2$ relations between these invariants and the Chern classes of the spin$^c$ index bundle of the family. As a result we discover ...
Tópico(s): Advanced Operator Algebra Research
2022 - Wiley | Journal of Topology
Takahiro Matsuyama, Yoshiharu Ohno, Kaori Yamamoto, Masato Ikedo, Masao Yui, Minami Furuta, Reina Fujisawa, Satomu Hanamatsu, Hiroyuki Nagata, Takahiro Ueda, Hirotaka Ikeda, Saki Takeda, Akiyoshi Iwase, Takashi Fukuba, Hokuto Akamatsu, Ryota Hanaoka, Ryoichi Kato, Kazuhiro Murayama, Hiroshi Toyama,
Tópico(s): Advanced MRI Techniques and Applications
2022 - Springer Science+Business Media | European Radiology
Hiroshi Nakagomi, Takahiko Mitsui, Hiroshi Shimura, Tatsuya Ihara, Satoru Kira, Norifumi Sawada, Masayuki Takeda,
Abstract Background We assessed the efficacy and safety of mirabegron, a β 3 -adrenoceptor agonist, in older adults (≥ 80 years old) with overactive bladder (OAB). Methods OAB patients aged ≥ 80 years were enrolled in this prospective, single-arm observational study. OAB was diagnosed based on the OAB symptom score (OABSS); i.e., a total score of ≥ 3 points and an urgency score of ≥ 2 points. Patients who received 50 mg mirabegron once daily were evaluated at the baseline and at 4, 8, and 12 weeks. The changes ...
Tópico(s): Urinary Tract Infections Management
2022 - BioMed Central | BMC Urology
Hokuto Nakayama, Hiroyuki Koga, Yuchen Long, Olivier Hamant, Ali Ferjani,
ABSTRACT The above-ground organs in plants display a rich diversity, yet they grow to characteristic sizes and shapes. Organ morphogenesis progresses through a sequence of key events, which are robustly executed spatiotemporally as an emerging property of intrinsic molecular networks while adapting to various environmental cues. This Review focuses on the multiscale control of leaf morphogenesis. Beyond the list of known genetic determinants underlying leaf growth and shape, we focus instead on ...
Tópico(s): Plant Reproductive Biology
2022 - The Company of Biologists | Journal of Cell Science
Min-Yao Jhu, Moran Farhi, Li Wang, R. N. Philbrook, Michael S. Belcher, Hokuto Nakayama, Kristina Zumstein, Steven D. Rowland, M. Ron, Patrick M. Shih, Neelima Sinha,
Cuscuta species (dodders) are agriculturally destructive, parasitic angiosperms. These parasitic plants use haustoria as physiological bridges to extract nutrients and water from hosts. Cuscuta campestris has a broad host range and wide geographical distribution. While some wild tomato relatives are resistant, cultivated tomatoes are generally susceptible to C. campestris infestations. However, some specific Heinz tomato (Solanum lycopersicum) hybrid cultivars exhibit resistance to dodders in the ...
Tópico(s): Plant Gene Expression Analysis
2022 - Oxford University Press | PLANT PHYSIOLOGY
Akinori Minagi, Hokuto Hirano, Kazuhiro Takemoto,
Transfer learning from natural images is used in deep neural networks (DNNs) for medical image classification to achieve a computer-aided clinical diagnosis. Although the adversarial vulnerability of DNNs hinders practical applications owing to the high stakes of diagnosis, adversarial attacks are expected to be limited because training datasets (medical images), which are often required for adversarial attacks, are generally unavailable in terms of security and privacy preservation. Nevertheless, ...
Tópico(s): COVID-19 diagnosis using AI
2022 - Multidisciplinary Digital Publishing Institute | Journal of Imaging
Yared Beyene Yohannes, Shouta M.M. Nakayama, John Yabe, Haruya Toyomaki, Andrew Kataba, Hokuto Nakata, Kaampwe Muzandu, Yoshinori Ikenaka, Kennedy Choongo, Mayumi Ishizuka,
Interindividual genetic variations determine human's susceptibility to heavy metal-induced toxicity. Thus, we analyzed blood concentrations of lead (Pb) and cadmium (Cd) in 140 lead-exposed children. Genotyping of the glutathione S-transferase (GST) genes, GSTM1, GSTT1, and GSTP1 genes, was carried out to investigate their possible association with heavy metal concentrations and the risk of susceptibility to Pb toxicity. Exposure to both heavy metals was prevalent among the children. The blood Pb level ...
Tópico(s): Glutathione Transferases and Polymorphisms
2021 - Springer Science+Business Media | Environmental Science and Pollution Research
Yuanyuan Hong, Moriaki Yasuhara, Hokuto Iwatani, Anne Chao, Paul G. Harnik, Chih‐Lin Wei,
Natural and anthropogenic factors shape present-day benthic marine ecosystems. Understanding their combined influence on benthic communities is limited, however, by a lack of biological monitoring. Using a conservation paleobiology approach, this study establishes biological baselines and assesses the effects of natural and anthropogenic environmental change on benthic communities in an urbanized subtropical seascape. We compared subsurface (“past”, covering approximately the last 50–100 years) and ...
Tópico(s): Marine animal studies overview
2021 - Elsevier BV | Anthropocene
Yuanyuan Hong, Moriaki Yasuhara, Hokuto Iwatani, Paul G. Harnik, Anne Chao, Jonathan D. Cybulski, Yuan Liu, Yuefei Ruan, Xiangdong Li, Chih‐Lin Wei,
Tópico(s): Marine and coastal plant biology
2021 - Elsevier BV | Marine Micropaleontology
Hokuto Hirano, Akinori Minagi, Kazuhiro Takemoto,
Abstract Background Deep neural networks (DNNs) are widely investigated in medical image classification to achieve automated support for clinical diagnosis. It is necessary to evaluate the robustness of medical DNN tasks against adversarial attacks, as high-stake decision-making will be made based on the diagnosis. Several previous studies have considered simple adversarial attacks. However, the vulnerability of DNNs to more realistic and higher risk attacks, such as universal adversarial perturbation ( ...
Tópico(s): PARP inhibition in cancer therapy
2021 - BioMed Central | BMC Medical Imaging
Hokuto Nakayama, Steven D. Rowland, Zizhang Cheng, Kristina Zumstein, Julie Kang, Yohei Kondo, Neelima Sinha,
Domesticated plants display diverse phenotypic traits. However, the influence of breeding effort on this phenotypic diversity remains unknown. Here, we demonstrate that a single nucleotide deletion in the homeobox motif of BIPINNATA, a BEL-LIKE HOMEODOMAIN gene, led to a highly complex leaf phenotype in an heirloom tomato (Solanum lycopersicum), Silvery Fir Tree (SiFT), which is used as a landscaping and ornamental plant. A comparative gene network analysis revealed that repression of SOLANIFOLIA, ...
Tópico(s): Plant Reproductive Biology
2021 - Elsevier BV | Current Biology
Hokuto Nakata, Shouta M.M. Nakayama, John Yabe, Kaampwe Muzandu, Haruya Toyomaki, Yared Beyene Yohannes, Andrew Kataba, Golden Zyambo, Yoshinori Ikenaka, Kennedy Choongo, Mayumi Ishizuka,
Tópico(s): Heavy metals in environment
2021 - Elsevier BV | Chemosphere
Hokuto Arase, Shunsuke Yamada, Hiroto Hiyamuta, Masatomo Taniguchi, Masanori Tokumoto, Kazuhiko Tsuruya, Toshiaki Nakano, Takanari Kitazono,
Abstract Modified creatinine (Cr) index, calculated by age, sex, pre-dialysis serum Cr concentration, and Kt/V for urea, is an indicator of skeletal muscle mass in hemodialysis (HD) patients. It remains unknown whether the modified Cr index predicts infection-related mortality in this population. We investigated the association between the modified Cr index and infection-related mortality. A total of 3046 patients registered in the Q-Cohort Study, a multicenter, observational study of HD patients, ...
Tópico(s): Iron Metabolism and Disorders
2020 - Nature Portfolio | Scientific Reports
Hokuto Ushijima, Junichiro Kawamura, Kazuki Ueda, Yoshinori Yane, Yasumasa Yoshioka, Koji Daito, Tadao Tokoro, Jin‐ichi Hida, Kiyotaka Okuno,
Abstract Intraoperative visualization of lymphatic flow could guide surgeons performing laparoscopic colon cancer surgery on the extent of intestinal resection required. The purpose of this study was to investigate indocyanine green fluorescence imaging for intraoperative detection of lymphatic flow and nodes in such patients. All patients undergoing elective laparoscopic surgery for colorectal cancer from October 2016 to July 2017 were included in this study. Indocyanine green was injected submucosally ...
Tópico(s): Colorectal Cancer Screening and Detection
2020 - Nature Portfolio | Scientific Reports
Skye Yunshu Tian, Moriaki Yasuhara, Yuanyuan Hong, Huai-Hsuan May Huang, Hokuto Iwatani, Wing‐Tung Ruby Chiu, Briony Mamo, Hisayo Okahashi, Tine L. Rasmussen,
Better understanding of deglacial meltwater pulses (MWPs) is imperative for future predictions of human-induced warming and abrupt sea-level change because of their potential for catastrophic damage. However, our knowledge of the second largest meltwater pulse MWP-1B that occurred shortly after the start of the Holocene interglacial remains very limited. Here, we studied fossil ostracods as paleoenvironmental indicators of water depth, salinity, and temperature in two marine sediment cores from Storfjorden, ...
Tópico(s): Methane Hydrates and Related Phenomena
2020 - Elsevier BV | Quaternary Science Reviews
Yukari Yada, Akihide Ohkuchi, Katsufumi Otsuki, Keiji Goishi, Mari Takahashi, Naohiro Yonemoto, Shigeru Saito, Satoshi Kusuda, Hajime Ota, Kiyotaka Kosugiyama, Kazuhiko Okuyama, Masato Mizushima, H. Negishi, Shinichi Koshida, Mayumi Kasai, Motonari Okabe, Akira Sato, Hiroyuki Adachi, Michio Banzai, Kazuhiro Akaba, Rika Suzuki, Naohisa Ishibashi, Takashi Watanabe, Yoshio Kasuga, Takashi Kameda, Toru Fujiu, Takeshi Takagi, Kenichi Maruyama, Masahiko Higashino, Tomomi Naito, Yoshimasa Kamei, Tetsuya Kunikata, Yoshinori Iitsuka, Harumi Otsuka, Yuka Yamamoto, Mie Yamada, Masaki Daigo, Hironobu Hyodo, Ayumi Sato, Noriko Kataoka, Satoko Yamanaka, Aya Okahashi, Yuki Kojima, Shigenori Kabashima, Yoshie Nakamura, Rina Okuno, Seiko Hirose, Koichi Sugahara, Satsuki Okamoto, Sumiko Hara, Wakako Shima, Takeshi Suzuki, Hideyuki Kagawa, Kenichiro Fujioka, Akiko Kurasaki, Ayako Miura, Isamu Hokuto, Toru Arase, Nobuhiko Taguchi, Kazuki Sekiguchi, Tomoyo Matsuo, Emi Ohnuma, Kana Fujiwara, Miyuki Ogawa, Azusa Uozumi, Noriyuki Yokomichi, Akane Hirose, Mika Okuda, Ayako Fukuyama, Hitoshi Ishimoto, Kanako Mitsuzuka, Shinya Kondo, Miyuki Kitazawa, Norihiko Kikuchi, Yumiko Miyashita, Chiharu Tsutsumi, Shuhei Terada, Shigeru Ohki, Takakazu Kawamura, Masako Yasuda, Yoshiki Soeno, Takumi Kurabayashi, Yoshihisa Nagayama, Satoshi Yoneda, Tomomi Shiga, Seiji Hayashi, Hiroyuki Tsuda, Makoto Oshiro, Takafumi Ushida, Teruyuki Mizutani, H. Asada, Ryousuke Miura, Ryō Tanaka, Noriko Kato, Yuko Sasaki, Takehiko Yokoyama, T Hirooka, Takaharu Yamada, Kaori Maruwaka, Syunsuke Nagara, Satoko Fukaya, Mari Koroki, Taihei Tanaka, Shigehiko Morikawa, Shigeru Honda, Haruki Sassa, Takeshi Sahashi, Hiroko Torii, Tadahiro Yasuo, Nozomi Kuriyama, J Okada, Moe Kano, Noriyoshi Oki, Mieko Inagaki, Yousuke Mizuno, Masayo Fujisaka, Akihiro Takatera, Takeo Mure, Katsuhiko Yoshii, Yasuko Furuichi, Akiko Kanto, On Fukui, Shusaku Hayashi, Hitomi Ono, Eri Fujikawa, Masayuki Someya, Makiko Ikeda, Kentaro Nakanishi, Akiko Yamashita, Haruna Kawaguchi, Ryo Yamamoto, Jun Sasahara, Takeshi Kanagawa, Satoshi Yamamoto, Yosuke Imanishi, Misuzu Yoshida, Eri Yano, Ayumi Murayama, Kazue Morikawa, Natsuko Tabata, Ryosuke Araki, Eriko Iwasaki, Narutaka Mochizuki, Akiko Kobayashi, Akiko Takeda, Akiko Kobayashi, Masaya Hirose, Nao Taguchi, Hiroshi Satō, Kenji Oida, Rie Sakai‐Bizmark, Saeko Imai, Reona Shiro, Minami Okudate, Yoko Matsuda, Yoshinobu Nishida, Aya Toyofuku, Shigeto Hara, Hiroko Kurioka, Tomoya Mizunoe, Syouhei Eto, Takahiro Nobuzane, Kousyou Higuchi, Terumi Miwa, Keiko Hasegawa, Yuko Matsubara, Masaaki Ohta, Takafumi Watanabe, Takako Ohmaru‐Nakanishi, Kana Kashinoura, Maki Goto, Hiroshi Kanda, Kiyomi Tsukimori, Yasushi Takahata, Makoto Nomiyama, T Takayanagi, Syuichiro Yoshimura, Kouhei Kotera, Hisanobu Fukuda, Hiroko Hiraki, Noriko Nagata, Kazuhisa Nakashima, Junya Miyoshi, Takafumi Obara, Kentaro Kai, Yuichi Furukawa, Satoshi Eto, Tomoko Oishi, Misaki Nakashima, Aya Yamauchi, Yuki Kodama, Takako Ohata, Haruka Arakaki, Kei Miyakoshi, Mariko Hida,
Our aim was to evaluate the association between ritodrine and magnesium sulfate (MgSO4) and the occurrence of neonatal hyperkalemia or hypoglycemia among late preterm infants in a retrospective cohort study. We used a nationwide obstetrical database from 2014. A total of 4,622 live preterm infants born at 32-36 gestational weeks participated. Fourteen risk factors based on both clinical relevance and univariate analysis were adjusted in multivariable logistic regression analyses. Neonatal hyperkalemia ...
Tópico(s): Infant Health and Development
2020 - Nature Portfolio | Scientific Reports